{"id":61476,"date":"2024-02-28T07:42:25","date_gmt":"2024-02-28T07:42:25","guid":{"rendered":"https:\/\/medsname.com\/seretra\/"},"modified":"2026-04-30T10:23:34","modified_gmt":"2026-04-30T10:23:34","slug":"seretra","status":"publish","type":"product","link":"https:\/\/medsbase.com\/da\/seretra\/","title":{"rendered":"Seretra"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Seretra?<\/h3>\n<p><strong>Seretra<\/strong> indeholder <strong>seratrodast 80 mg<\/strong>, en <strong>selective thromboxane A2 (TXA2) receptor antagonist<\/strong> used as preventer therapy for asthma and allergic rhinitis. Seratrodast blocks the TXA2 receptor on bronchial smooth muscle, eosinophils, and platelets \u2014 preventing TXA2-mediated bronchoconstriction, eosinophil recruitment, and airway hyperresponsiveness. It was developed and is mainly used in Japan; less widely available outside Asia. Used as add-on preventer alongside ICS in patients with persistent asthma. Onset of preventer benefit takes <strong>1\u20132 uger<\/strong> of daily dosing.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Hvad du f\u00e5r med MedsBase:<\/strong> WHO-GMP certificeret producent \u00b7 Diskret emballage \u00b7 Verdensomsp\u00e6ndende forsendelse \u00b7 1.400+ verificerede <a href=\"https:\/\/medsbase.com\/da\/reviews\/\">kundeanmeldelser<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er d\u00e6kket af vores <a href=\"https:\/\/medsbase.com\/da\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis din pakke ikke ankommer inden for 20 hverdage, sender vi en erstatning.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>Vores generiske medicin kommer fra WHO-GMP certificerede producenter og sendes verdensomsp\u00e6ndende i diskret, neutral emballage \u2014 ingen medicinnavn p\u00e5 pakkens ydre. Kortbetalinger h\u00e5ndteres af en reguleret processor (kontoudtogsbeskrivelser inkluderer en reguleret betalingsprocessor \u2014 aldrig \u201cMedsBase\u201d eller medicinnavn). Crypto og SEPA bankoverf\u00f8rsel accepteres ogs\u00e5. Hver ordre er d\u00e6kket af vores Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Krypteret betaling<\/strong> \u00b7 <strong>\ud83d\udcb3 Verificeret betalingsprocessor<\/strong> \u00b7 <strong>\ud83d\ude9a Verdensomsp\u00e6ndende forsendelse<\/strong> \u00b7 <strong>\u2b50 4,9\/5 fra 1.400+ kunder<\/strong>\n<\/div>\n<h2>What Is Seretra?<\/h2>\n<p>Seretra contains seratrodast \u2014 a niche anti-asthma agent introduced in Japan in 1995. Seratrodast targets the thromboxane A2 (TXA2) receptor \u2014 a contrast to leukotriene receptor antagonists (montelukast) which target the cysteinyl leukotriene receptor. Both TXA2 and leukotrienes are inflammatory mediators released during the allergic cascade.<\/p>\n<h2>How Does Seratrodast Work?<\/h2>\n<ul>\n<li><strong>TXA2 receptor blockade<\/strong> on bronchial smooth muscle prevents TXA2-mediated bronchoconstriction<\/li>\n<li><strong>Reduces eosinophil recruitment<\/strong> to airways<\/li>\n<li><strong>Decreases airway hyperresponsiveness<\/strong> over 1\u20132 weeks of dosing<\/li>\n<li><strong>Mild platelet inhibition<\/strong> \u2014 TXA2 is a potent platelet aggregator; this effect is rarely clinically significant<\/li>\n<\/ul>\n<h2>\u2014 det forst\u00e6rker den normale fysiologiske respons snarere end at udl\u00f8se en kunstigt.<\/h2>\n<ul>\n<li><strong>Persisterende astma<\/strong> \u2014 add-on preventer when ICS alone is inadequate<\/li>\n<li><strong>Allergisk rhinitis<\/strong> \u2014 supplement<\/li>\n<li><strong>Hostevariant astma<\/strong><\/li>\n<li><strong>Aspirin-exacerbated respiratory disease<\/strong> (AERD) \u2014 niche use<\/li>\n<\/ul>\n<h2>Seretra Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Patient<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dosis<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Hyppighed<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Voksne<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>80 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily after dinner<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Leversvigt<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Reducer dosis med 50%<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">En gang dagligt<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Side Effects of Seretra<\/h2>\n<ul>\n<li>Nausea, dyspepsia<\/li>\n<li>Hovedpine<\/li>\n<li>Mild dizziness<\/li>\n<li>Let forh\u00f8jelse af leverenzymer<\/li>\n<li>Rarely: rash, fatigue<\/li>\n<\/ul>\n<p><strong>Alvorligt \u2014 stop og s\u00f8g hj\u00e6lp:<\/strong><\/p>\n<ul>\n<li>Hepatitis (jaundice, dark urine, RUQ pain)<\/li>\n<li>Alvorlig allergisk reaktion<\/li>\n<li>Alvorlig vedvarende opkastning<\/li>\n<\/ul>\n<h2>Advarsler og forholdsregler<\/h2>\n<ul>\n<li><strong>Overv\u00e5gning af leverfunktion:<\/strong> baseline LFTs and periodic monitoring during long-term use.<\/li>\n<li><strong>Forts\u00e6t med ICS<\/strong> if previously prescribed; seratrodast is add-on, not replacement.<\/li>\n<li><strong>Ikke en akutmedicin.<\/strong> Use SABA (Asthalin, Levolin) for acute attacks.<\/li>\n<li><strong>Graviditet og amning:<\/strong> limited data; avoid unless benefit clear.<\/li>\n<li><strong>Bleeding disorders:<\/strong> mild TXA2 inhibition could theoretically prolong bleeding; rarely clinically significant.<\/li>\n<\/ul>\n<h2>Kontraindikationer<\/h2>\n<ul>\n<li>Hypersensitivity to seratrodast<\/li>\n<li>Sv\u00e6r leversvigt<\/li>\n<li>Active hepatitis<\/li>\n<\/ul>\n<h2>L\u00e6gemiddelinteraktioner<\/h2>\n<ul>\n<li>Aspirin and other antiplatelet agents \u2014 additive bleeding risk (rarely clinically significant)<\/li>\n<li>Warfarin \u2014 monitor INR<\/li>\n<li>Other hepatotoxic drugs \u2014 monitor LFTs<\/li>\n<\/ul>\n<h2>Opbevaring<\/h2>\n<ul>\n<li>Opbevares under <strong>25\u00b0C<\/strong> p\u00e5 et k\u00f8ligt, t\u00f8rt sted v\u00e6k fra direkte sollys.<\/li>\n<li>Opbevar i originalemballage inden brug for at beskytte mod fugt og lys.<\/li>\n<li>Brug ikke efter den udl\u00f8bsdato, der er trykt p\u00e5 strimlen.<\/li>\n<li>Opbevar utilg\u00e6ngeligt for b\u00f8rn.<\/li>\n<\/ul>\n<h2>Relaterede alternativer p\u00e5 MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/da\/asthalin-inhaler\/\"><strong>Asthalin Inhalator \u2014 salbutamol lindrende<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/budecort-inhaler\/\"><strong>Budecort Inhalator \u2014 budesonide ICS forebyggende<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/foracort-inhaler\/\"><strong>Foracort Inhalator \u2014 budesonide + formoterol ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/montair\/\"><strong>Montair \u2014 montelukast LTRA tablet<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/tiova-inhaler\/\"><strong>Tiova Inhalator \u2014 tiotropium LAMA til KOL<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Ofte stillede sp\u00f8rgsm\u00e5l<\/h2>\n<h3>How is seratrodast different from montelukast?<\/h3>\n<p>Both block specific allergic mediators. Montelukast (Montair) blocks the cysteinyl leukotriene CysLT1 receptor. Seratrodast blocks the thromboxane A2 receptor. Different mediators, different targets, similar add-on niche. Montelukast has more global use and a stronger evidence base; seratrodast is mainly used in Japan and parts of Asia.<\/p>\n<h3>Can I take Seretra alongside montelukast?<\/h3>\n<p>Combination is not standard. Discuss with your prescriber \u2014 there is no established additional benefit over ICS-LABA + LTRA.<\/p>\n<h3>How long until Seretra works?<\/h3>\n<p>1\u20132 weeks for noticeable improvement; 4\u20138 weeks for full preventer effect on exacerbation rate.<\/p>\n<h3>Is Seretra a rescue inhaler?<\/h3>\n<p>No \u2014 onset is far too slow. Use a SABA (Asthalin, Levolin) for acute attacks.<\/p>\n<h3>Why monitor liver function?<\/h3>\n<p>Mild liver enzyme elevation is a known side effect. Baseline LFTs and periodic monitoring are recommended.<\/p>\n<h3>Will Seretra replace my inhaler?<\/h3>\n<p>No \u2014 seratrodast is an oral add-on. Continue ICS or ICS-LABA inhaler therapy.<\/p>\n<h3>Is Seretra evidence-based?<\/h3>\n<p>Yes, but mainly through Japanese trials. Evidence base is smaller than for montelukast or ICS-LABA combinations. Reasonable as add-on in selected patients.<\/p>\n<h3>Can children take Seretra?<\/h3>\n<p>Limited paediatric data; specialist supervision required.<\/p>\n<h3>Is Seretra safe in pregnancy?<\/h3>\n<p>Limited data; avoid unless benefit clear.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medicinsk ansvarsfraskrivelse:<\/strong> Denne side er uddannelsesm\u00e6ssig og erstatter ikke professionel medicinsk r\u00e5dgivning. Konsulter altid en kvalificeret sundhedsfaglig person, f\u00f8r du starter, stopper eller \u00e6ndrer enhver inhalator eller respirationsmedicin, is\u00e6r hvis du har andre medicinske tilstande, tager andre receptpligtige l\u00e6gemidler, er gravid eller ammer, eller er over 65 \u00e5r.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Relaterede alternativer<\/h3>\n<p>Andre produkter inden for <strong>Kroniske tilstande<\/strong> som kunder ogs\u00e5 ser:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/da\/tenof-em\/\">Tenof EM<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/headset\/\">Headset<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/maxiflo-rotacaps\/\">Maxiflo Rotacaps<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/neomercazole\/\">Neomercazole<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/da\/tridon\/\">Tridon<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Reducerer luftvejsbet\u00e6ndelse<br \/>\n\u2705 Forbedrer lungefunktion<br \/>\n\u2705 Lindrer astmasymptomer<br \/>\n\u2705 Prevents bronchoconstriction<br \/>\n\u2705 Enhances respiratory health<\/p>\n<p>Seretra contains Seratrodast.<\/p>","protected":false},"featured_media":61477,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[5040,5041],"class_list":{"0":"post-61476","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-seratrodast","10":"product_tag-seretra","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product\/61476","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/comments?post=61476"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/media\/61477"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/media?parent=61476"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_brand?post=61476"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_cat?post=61476"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_tag?post=61476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}