{"id":4462,"count":2,"description":"Hyperthyroidism (overactive thyroid) most commonly caused by Graves' disease (autoimmune TSH-receptor antibody-mediated), toxic multinodular goitre, or solitary toxic adenoma. Symptoms include weight loss with normal\/increased appetite, palpitations, tremor, heat intolerance, anxiety, frequent stools, and (in Graves') eye signs (proptosis, lid lag, ophthalmopathy). The MedsBase Overactive Thyroid Treatment catalogue carries the antithyroid thionamide drugs that block thyroid peroxidase and reduce hormone synthesis.\n\n<strong>Lagerf\u00f8rte muligheder.<\/strong> Methimazol (det moderne foretrukne thionamid - \u00e9n gang daglig dosering, mindre hepatotoksisk end propylthiouracil undtagen i f\u00f8rste trimester af graviditet og thyreotoxisk krise) f\u00f8res som <a href=\"https:\/\/medsbase.com\/da\/methimez\/\">Methimez<\/a>. Carbimazol (prodrug for methimazol, bredt anvendt i UK\/Europa\/Indien\/Asien) som <a href=\"https:\/\/medsbase.com\/da\/neomercazole\/\">Neomercazole<\/a>.\n\n<strong>Brugsanvisning.<\/strong> Initial dose for moderate Graves' disease: methimazole 15\u201330 mg daily or carbimazole 20\u201340 mg daily, titrated based on TSH and free T4 measured every 4\u20136 weeks. Most patients achieve euthyroid state within 6\u201312 weeks. Long-term options: continue antithyroid drug for 12\u201318 months (40% remission rate after stopping in Graves'), radioactive iodine ablation (definitive but causes permanent hypothyroidism), or surgical thyroidectomy. Beta-blockers (propranolol \u2014 see <a href=\"https:\/\/medsbase.com\/da\/heart-blood-pressure\/\">Hjerte &amp; blodtryk<\/a>) til symptomatisk kontrol af hjertebanken, tremor og angst mens man venter p\u00e5 antithyreoide medicinens virkning.\n\n<strong>Vigtigt.<\/strong> <strong>Obligatorisk baseline FBC og LFT'er f\u00f8r behandling.<\/strong> Antithyreoide l\u00e6gemidler for\u00e5rsager agranulocytose hos 0,1\u20130,5% af patienterne (typisk inden for 90 dage, h\u00f8jere dosis \u00f8ger risikoen) - pludselig feber, ondt i halsen, munds\u00e5r kr\u00e6ver \u00f8jeblikkelig FBC og behandlingsoph\u00f8r hvis neutropeni. Hepatotoksicitet - propylthiouracil mere end methimazol; LFT-overv\u00e5gning under tidlig behandling. Graviditet: propylthiouracil foretrukket i f\u00f8rste trimester (mindre teratogen - methimazol-induceret aplasia cutis og choanal atresi), skift derefter til methimazol i andet trimester. Subakut thyreoiditis pr\u00e6senterer med hyperthyreose men reagerer IKKE p\u00e5 antithyreoide l\u00e6gemidler (NSAID'er og betablokkere er passende; thyreoidscanning hj\u00e6lper med differentiering). Alle MedsBase-produkter afsendes fra <strong>WHO-GMP certificerede producenter<\/strong> og er d\u00e6kket af vores <a href=\"https:\/\/medsbase.com\/da\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a>.","link":"https:\/\/medsbase.com\/da\/overactive-thyroid-treatment\/","name":"Behandling af overaktiv skjoldbruskkirtel","slug":"overactive-thyroid-treatment","taxonomy":"product_cat","parent":3223,"meta":[],"menu_order":0,"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_cat\/4462","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_cat"}],"about":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/taxonomies\/product_cat"}],"up":[{"embeddable":true,"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product_cat\/3223"}],"wp:post_type":[{"href":"https:\/\/medsbase.com\/da\/wp-json\/wp\/v2\/product?product_cat=4462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}