{"id":52220,"date":"2023-09-20T09:30:34","date_gmt":"2023-09-20T09:30:34","guid":{"rendered":"https:\/\/medsname.com\/urimax-d\/"},"modified":"2026-04-30T16:30:22","modified_gmt":"2026-04-30T16:30:22","slug":"urimax-d","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/urimax-d\/","title":{"rendered":"Urimax D"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">\u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7<\/h3>\n<p style=\"margin-bottom:0;\"><strong>Urimax D<\/strong> \u2014 tamsulosin 0.4 mg + dutasteride 0.5 mg (Cipla Inc). Combined alpha-1A blocker + dual 5-alpha-reductase inhibitor for moderate-to-severe BPH with prostate &gt;30 mL or PSA &gt;1.5 ng\/mL. Treats symptoms (alpha) AND shrinks the gland over 6-12 months (5ARI).<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f7f7f7;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 6px 0;\"><strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong><\/p>\n<ul style=\"margin:6px 0 0 22px;padding:0;list-style:disc;\">\n<li>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/li>\n<li>\u03a3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u03c3\u03b5 \u03b1\u03c0\u03bb\u03cc \u03c6\u03ac\u03ba\u03b5\u03bb\u03bf \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/li>\n<li>\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/li>\n<li>\u0391\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc 1,400+ \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 (<a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2<\/a>)<\/li>\n<\/ul>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:10px 14px;margin:14px 0;border-radius:3px;\">\ud83d\udce6 <strong>\u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2:<\/strong> \u03b1\u03bd \u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae, \u03c4\u03b7\u03bd \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03bf \u03ba\u03cc\u03c3\u03c4\u03bf\u03c2. <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u0394\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03b7\u03bd \u03c0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae<\/a>.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Urimax D ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor \u2014 never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:3px;\"><strong>Pregnancy red-box \u2014 handle with care<\/strong><br \/>Dutasteride is teratogenic. Pregnant women must NOT handle leaking or crushed capsules \u2014 skin absorption can affect male fetal genital development. Men taking dutasteride must NOT donate blood for at least 6 months after the last dose (5-week half-life). Capsules should be swallowed whole.<\/div>\n<h2>Why combination therapy<\/h2>\n<p>The CombAT trial (Combination of Avodart and Tamsulosin, n=4,844, 4 years) showed that dutasteride + tamsulosin was superior to either monotherapy for moderate-to-severe BPH, particularly in men with:<\/p>\n<ul>\n<li>Prostate volume &gt;30 mL<\/li>\n<li>PSA &gt;1.5 ng\/mL (a marker of prostate volume)<\/li>\n<li>IPSS &gt;13 (moderate-to-severe symptoms)<\/li>\n<\/ul>\n<p>Combination therapy reduced acute urinary retention by 67.8% and BPH-related surgery by 70.6% compared with tamsulosin alone over 4 years.<\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:12px 16px;margin:14px 0;border-radius:3px;\"><strong>PSA halving rule<\/strong><br \/>Dutasteride approximately halves serum PSA after 6 months. When interpreting PSA in a man on dutasteride, double the measured value before applying age-based reference ranges. A PSA that fails to halve, or that rises while on dutasteride, is suspicious for prostate cancer and warrants urology review \u2014 do not assume the rise is benign.<\/div>\n<h2>\u03a7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7<\/h2>\n<p>One capsule once daily, 30 minutes after the same meal each day. Swallow whole \u2014 do NOT crush, chew, or open. Improvement in symptoms (alpha component) is noticeable in 1-2 weeks; gland-shrinkage effect (dutasteride) takes 3-6 months and continues to improve out to 12 months.<\/p>\n<h2>\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>Tamsulosin component:<\/strong> dizziness, retrograde ejaculation (~5-15%), nasal congestion, postural hypotension<\/li>\n<li><strong>Dutasteride component:<\/strong> reduced libido, erectile dysfunction (~4-7%), reduced ejaculate volume, gynaecomastia (rare)<\/li>\n<li><strong>Both:<\/strong> generally well tolerated; sexual side effects are the most common reason for stopping<\/li>\n<li><strong>IFIS:<\/strong> tamsulosin component still causes Intraoperative Floppy Iris Syndrome \u2014 tell any ophthalmologist before cataract surgery<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:3px;\"><strong>IFIS<\/strong><br \/>Tamsulosin causes Intraoperative Floppy Iris Syndrome \u2014 disclose to any ophthalmologist before cataract surgery, even years after stopping.<\/div>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>When will I notice improvement?<\/h3>\n<p>Urinary flow improves within 1-2 weeks (alpha blocker effect). Gland-shrinkage and reduced retention\/surgery risk takes 3-6 months and continues to improve out to 1 year (dutasteride effect).<\/p>\n<h3>Should I keep the alpha blocker forever?<\/h3>\n<p>CombAT data showed continued benefit at 4 years with combination therapy. Some men can later step down to dutasteride alone after symptoms have stabilised on combination, but talk to your urologist before changing \u2014 withdrawal of the alpha blocker can cause flare in flow symptoms.<\/p>\n<h3>Can I father a child while taking this?<\/h3>\n<p>Dutasteride affects semen parameters and crosses into semen. Most clinicians recommend stopping dutasteride at least 6 months before conception attempts. Discuss with your fertility specialist.<\/p>\n<h3>What about PSA monitoring?<\/h3>\n<p>Dutasteride approximately halves PSA. Double the measured PSA when interpreting against age-based ranges. Any rise from the new baseline warrants prostate cancer evaluation.<\/p>\n<h3>Cataract surgery?<\/h3>\n<p>Tell the ophthalmologist about tamsulosin use even if you stopped years ago \u2014 it causes Intraoperative Floppy Iris Syndrome and changes the surgical approach.<\/p>\n<h3>Sexual side effects \u2014 will they reverse?<\/h3>\n<p>Most reverse on stopping the drug, though some men report persistent symptoms. If sexual side effects are unacceptable, discuss switching to a tamsulosin + finasteride 5 mg combination (similar gland-shrinkage benefit, slightly different side-effect profile).<\/p>\n<h3>Can I take this with sildenafil\/tadalafil for ED?<\/h3>\n<p>Yes, but separate by \u22654 hours to avoid additive hypotension. Daily tadalafil 5 mg has the cleanest profile and is itself approved for BPH symptoms.<\/p>\n<h3>\u03a4\u03b9 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd \u03c7\u03ac\u03c3\u03c9 \u03bc\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7;<\/h3>\n<p>Take it when you remember if it is still close to the normal time. If it is nearly time for the next dose, skip the missed one \u2014 do not double up.<\/p>\n<h3>Why is dutasteride preferred over finasteride here?<\/h3>\n<p>Dutasteride inhibits both type-1 and type-2 5-alpha-reductase isoenzymes, achieving more complete DHT suppression (~95% vs ~70% with finasteride). Some clinicians choose finasteride 5 mg for cost or side-effect reasons; clinical outcomes are broadly similar.<\/p>\n<h3>Does this prevent prostate cancer?<\/h3>\n<p>REDUCE trial showed dutasteride reduced low-grade prostate cancer detection but increased high-grade cancers slightly. It is NOT used for prostate cancer prevention. Continue routine cancer surveillance per local guidance.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Other BPH &#038; Urinary Medications<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/temsunol\/\">Temsunol<\/a> \u2014 tamsulosin 0.4 mg monotherapy \u2014 for symptomatic relief without gland shrinkage<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/temsunol-f\/\">Temsunol F<\/a> \u2014 tamsulosin + finasteride 5 mg \u2014 alternative 5ARI combo, lower cost<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/alfusin\/\">Alfusin<\/a> \u2014 alfuzosin 10 mg \u2014 non-selective alpha blocker<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/silofast\/\">Silofast<\/a> \u2014 silodosin \u2014 most selective alpha-1A; higher retrograde-ejaculation rate<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/finpecia\/\">Finpecia<\/a> \u2014 finasteride 1 mg for hair-loss; 5 mg version for BPH<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:18px 0;border-radius:3px;font-size:.95em;\"><strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u0391\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u0395\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd:<\/strong> \u0391\u03c5\u03c4\u03ae \u03b7 \u03c3\u03b5\u03bb\u03af\u03b4\u03b1 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c4\u03bf \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae\u03c2 \u03b1\u03c0\u03cc \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc. \u03a3\u03c5\u03b6\u03b7\u03c4\u03ae\u03c3\u03c4\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03bd\u03ad\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03bc\u03b5 \u03c4\u03bf\u03bd \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc \u03ae \u03c4\u03bf\u03bd \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03c0\u03bf\u03b9\u03cc \u03c3\u03b1\u03c2.<\/div>","protected":false},"excerpt":{"rendered":"<p>Urimax D (Tamsulosin 0.4 mg + Dutasteride 0.5 mg) \u2014 Cipla brand of the BPH combination therapy targeting both urinary symptoms and prostate gland shrinkage over 3-12 months.<\/p>","protected":false},"featured_media":52221,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3470,3202,3141,3342,3471,3142],"product_tag":[3474,3473,3476],"class_list":{"0":"post-52220","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-alpha-blocker","7":"product_cat-benign-prostatic-hyperplasia-bph-treatment","8":"product_cat-category-overview","9":"product_cat-general-health","10":"product_cat-hair-loss-treatment-for-men","11":"product_cat-mens-health","12":"product_tag-dutasteride","13":"product_tag-tamsulosin","14":"product_tag-urimax-d","16":"first","17":"outofstock","18":"shipping-taxable","19":"purchasable","20":"product-type-variable","21":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/52220","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=52220"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/52221"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=52220"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=52220"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=52220"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=52220"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}