{"id":52225,"date":"2023-09-20T09:30:34","date_gmt":"2023-09-20T09:30:34","guid":{"rendered":"https:\/\/medsname.com\/temsunol-capsule\/"},"modified":"2026-04-30T16:30:22","modified_gmt":"2026-04-30T16:30:22","slug":"temsunol-capsule","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/temsunol-capsule\/","title":{"rendered":"Temsunol Capsule"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">\u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u03b1\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7<\/h3>\n<p style=\"margin-bottom:0;\"><strong>Temsunol Capsule<\/strong> \u2014 tamsulosin 0.4 mg (Knoll Pharma). Uroselective alpha-1A blocker for benign prostatic hyperplasia (BPH) \u2014 relaxes bladder-neck and prostatic smooth muscle to improve urinary flow. One capsule once daily, 30 minutes after the same meal each day.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f7f7f7;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 6px 0;\"><strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong><\/p>\n<ul style=\"margin:6px 0 0 22px;padding:0;list-style:disc;\">\n<li>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/li>\n<li>\u03a3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u03c3\u03b5 \u03b1\u03c0\u03bb\u03cc \u03c6\u03ac\u03ba\u03b5\u03bb\u03bf \u03c7\u03c9\u03c1\u03af\u03c2 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/li>\n<li>\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/li>\n<li>\u0391\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc 1,400+ \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 (<a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2<\/a>)<\/li>\n<\/ul>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:10px 14px;margin:14px 0;border-radius:3px;\">\ud83d\udce6 <strong>\u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2:<\/strong> \u03b1\u03bd \u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae, \u03c4\u03b7\u03bd \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5 \u03c7\u03c9\u03c1\u03af\u03c2 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03bf \u03ba\u03cc\u03c3\u03c4\u03bf\u03c2. <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u0394\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03b7\u03bd \u03c0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae<\/a>.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Temsunol Capsule ships from a WHO-GMP certified manufacturer in plain packaging, billed through a regulated payment processor (the statement descriptor reads a regulated card-payment processor \u2014 never MedsBase or any medication name). Every order carries our 20-business-day Reshipment Assurance.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:3px;\"><strong>Cataract surgery \u2014 IFIS warning<\/strong><br \/>Tamsulosin causes Intraoperative Floppy Iris Syndrome (IFIS) in up to ~90% of treated patients. Tell any ophthalmologist about tamsulosin use BEFORE cataract or glaucoma surgery \u2014 even years after stopping. The surgeon needs to know to use intracameral phenylephrine, capsular tension rings, or a different surgical approach.<\/div>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:3px;\"><strong>First-dose orthostatic hypotension<\/strong><br \/>First dose can cause sudden drop in BP, especially in dehydrated, elderly, or volume-depleted patients. Take the first dose at bedtime to reduce fall risk. Avoid combining with PDE5 inhibitors (sildenafil\/tadalafil) within 4 hours.<\/div>\n<h2>How tamsulosin works<\/h2>\n<p>Tamsulosin is a uroselective alpha-1A adrenoceptor antagonist. The bladder neck and prostatic smooth muscle are densely populated with alpha-1A receptors; blocking them relaxes the dynamic component of bladder outlet obstruction without significantly affecting vascular alpha-1B receptors (which dominate blood vessels). This is why tamsulosin causes less postural hypotension than older non-selective alpha blockers (prazosin, doxazosin).<\/p>\n<p>Tamsulosin treats <strong>symptoms<\/strong> only \u2014 it does not shrink the prostate. To shrink the gland and reduce long-term progression risk, a 5-alpha-reductase inhibitor (finasteride or dutasteride) is added; combination therapy is superior in glands &gt;30 mL or PSA &gt;1.5 ng\/mL (CombAT trial).<\/p>\n<h2>\u03a7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:12px 0;\">\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;border:1px solid #ddd;\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th style=\"padding:8px;border:1px solid #ddd;\">\u0394\u03cc\u03c3\u03b7<\/th>\n<th style=\"padding:8px;border:1px solid #ddd;\">\u03a3\u03b7\u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9\u03c2<\/th>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">BPH urinary symptoms<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">0.4 mg once daily<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">30 min after the same meal each day<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Refractory symptoms<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">0.8 mg once daily<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Specialist-supervised; some markets do not approve this dose<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Acute urinary retention<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">0.4 mg\/day \u00d7 7-10 days before catheter trial-without-catheter<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Improves trial-without-catheter success ~25-30%<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Distal ureteric stones (off-label)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">0.4 mg\/day \u00d7 4 weeks<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Medical expulsive therapy for stones &lt;10 mm<\/td>\n<\/tr>\n<\/table>\n<p>Swallow whole \u2014 do not crush, chew, or open the capsule. Improvement in flow rate is typically noticed within 1-2 weeks; full benefit at 4-6 weeks.<\/p>\n<h2>\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>Common (1-10%):<\/strong> dizziness, headache, retrograde or absent ejaculation (~5-15% \u2014 reversible on stopping), nasal congestion (rhinitis), abnormal ejaculation<\/li>\n<li><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> orthostatic hypotension, syncope (especially first dose), palpitations, asthenia, decreased libido<\/li>\n<li><strong>Rare but important:<\/strong> priapism (medical emergency &gt;4 hours), Stevens-Johnson syndrome, IFIS during cataract surgery<\/li>\n<\/ul>\n<h2>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:12px 0;\">\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;border:1px solid #ddd;\">\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf<\/th>\n<th style=\"padding:8px;border:1px solid #ddd;\">\u0391\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/th>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Strong CYP3A4 inhibitors (ketoconazole, ritonavir, clarithromycin)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Up to 3\u00d7 tamsulosin AUC \u2014 avoid combination<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">\u0391\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 PDE5 (\u03c3\u03b9\u03bb\u03b4\u03b5\u03bd\u03b1\u03c6\u03af\u03bb\u03b7, \u03c4\u03b1\u03b4\u03b1\u03bb\u03b1\u03c6\u03af\u03bb\u03b7, \u03b2\u03b1\u03c1\u03b4\u03b5\u03bd\u03b1\u03c6\u03af\u03bb\u03b7)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Additive hypotension \u2014 separate by \u22654 hours; tadalafil 5 mg OD has the cleanest profile if combination is needed<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Other alpha blockers<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Do not combine \u2014 stacked vasodilation<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">\u0397 Cimetidine<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Modest rise in tamsulosin levels \u2014 usually clinically insignificant<\/td>\n<\/tr>\n<\/table>\n<div style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:10px 14px;margin:12px 0;border-radius:3px;\"><strong>\u03a3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae:<\/strong> Stand up slowly, especially first thing in the morning, for the first 1-2 weeks. The orthostatic effect fades as the body adapts.<\/div>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>When will I notice improvement?<\/h3>\n<p>Many men notice better flow within 7-14 days; full effect takes 4-6 weeks. If symptoms have not improved after 6 weeks, discuss with your clinician \u2014 combination with a 5-alpha-reductase inhibitor or alternative therapy may be warranted.<\/p>\n<h3>Can I take Temsunol Capsule on an empty stomach?<\/h3>\n<p>Manufacturer guidance is to take it 30 minutes after the same meal every day. Empty-stomach dosing increases peak plasma levels and the risk of orthostatic hypotension.<\/p>\n<h3>Will tamsulosin shrink my prostate?<\/h3>\n<p>No. Tamsulosin relaxes prostatic smooth muscle and improves urinary flow but does not change gland size. To shrink the prostate, a 5-alpha-reductase inhibitor (finasteride or dutasteride) is needed \u2014 often combined with tamsulosin in larger glands.<\/p>\n<h3>What about retrograde ejaculation?<\/h3>\n<p>About 5-15% of men experience reduced ejaculate volume or retrograde ejaculation (semen passes into the bladder). This is reversible on stopping the drug. It is more common with the 0.8 mg dose. The semen is harmless and reappears in the next urination.<\/p>\n<h3>I am having cataract surgery \u2014 does this matter?<\/h3>\n<p>Yes \u2014 tell your ophthalmologist immediately. Tamsulosin causes Intraoperative Floppy Iris Syndrome and the surgical approach needs to change. The effect persists for weeks-to-years after stopping, so do not just pause the drug \u2014 the surgeon still needs to know.<\/p>\n<h3>\u039c\u03c0\u03bf\u03c1\u03ce \u03bd\u03b1 \u03c0\u03af\u03bd\u03c9 \u03b1\u03bb\u03ba\u03bf\u03cc\u03bb;<\/h3>\n<p>Modest alcohol is acceptable but increases dizziness and orthostatic hypotension risk. Avoid alcohol when starting therapy or after a dose increase.<\/p>\n<h3>\u03a4\u03b9 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd \u03c7\u03ac\u03c3\u03c9 \u03bc\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7;<\/h3>\n<p>Take it when you remember if you are still close to your normal time. If it is nearly time for the next dose, skip the missed dose \u2014 do not double up.<\/p>\n<h3>Can women take tamsulosin?<\/h3>\n<p>Tamsulosin is sometimes used off-label in women for refractory urinary retention or distal ureteric stones (medical expulsive therapy). It is not a first-line female lower urinary tract symptom drug.<\/p>\n<h3>Does it interact with my BP medication?<\/h3>\n<p>Tamsulosin lowers BP modestly. If you are on multiple antihypertensives (especially other alpha blockers, ACE inhibitors, ARBs, or diuretics), expect a small additional drop. Monitor for postural symptoms; rarely need a dose adjustment of either drug.<\/p>\n<h3>Is the once-daily dose enough?<\/h3>\n<p>Yes \u2014 tamsulosin has a 9-15 hour half-life and once-daily 0.4 mg gives steady symptom control. Splitting the dose adds inconvenience without benefit.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Other BPH &#038; Urinary Medications<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/urimax-d\/\">Urimax D<\/a> \u2014 tamsulosin 0.4 mg + dutasteride 0.5 mg fixed combo for prostates &gt;30 mL<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/alfusin\/\">Alfusin<\/a> \u2014 alfuzosin 10 mg \u2014 alternative non-selective alpha blocker, slightly different side-effect profile<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/silofast\/\">Silofast<\/a> \u2014 silodosin 4\/8 mg \u2014 another uroselective alpha-1A blocker; higher retrograde-ejaculation rate but less BP effect<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/finpecia\/\">Finpecia<\/a> \u2014 finasteride 1 mg \u2014 5ARI for hair loss; 5 mg version for BPH gland shrinkage<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/urotel-xl\/\">Urotel XL<\/a> \u2014 tolterodine 4 mg ER \u2014 for overactive bladder symptoms, NOT for BPH<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:18px 0;border-radius:3px;font-size:.95em;\"><strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u0391\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u0395\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd:<\/strong> \u0391\u03c5\u03c4\u03ae \u03b7 \u03c3\u03b5\u03bb\u03af\u03b4\u03b1 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c0\u03bb\u03b7\u03c1\u03bf\u03c6\u03bf\u03c1\u03af\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c4\u03bf \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae\u03c2 \u03b1\u03c0\u03cc \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc. \u03a3\u03c5\u03b6\u03b7\u03c4\u03ae\u03c3\u03c4\u03b5 \u03ba\u03ac\u03b8\u03b5 \u03bd\u03ad\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03bc\u03b5 \u03c4\u03bf\u03bd \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc \u03ae \u03c4\u03bf\u03bd \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03c0\u03bf\u03b9\u03cc \u03c3\u03b1\u03c2.<\/div>","protected":false},"excerpt":{"rendered":"<p>Temsunol Capsule (Tamsulosin 0.4 mg) \u2014 Knoll Pharma alpha-1A blocker for benign prostatic hyperplasia. Capsule formulation for once-daily use 30 minutes after the same meal each day.<\/p>","protected":false},"featured_media":52226,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3470,3202,3141,3342,3142],"product_tag":[3473,3477],"class_list":{"0":"post-52225","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-alpha-blocker","7":"product_cat-benign-prostatic-hyperplasia-bph-treatment","8":"product_cat-category-overview","9":"product_cat-general-health","10":"product_cat-mens-health","11":"product_tag-tamsulosin","12":"product_tag-temsunol","14":"first","15":"outofstock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/52225","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=52225"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/52226"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=52225"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=52225"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=52225"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=52225"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}