{"id":52869,"date":"2023-09-20T09:39:34","date_gmt":"2023-09-20T09:39:34","guid":{"rendered":"https:\/\/medsname.com\/evalon-cream\/"},"modified":"2026-05-07T16:23:57","modified_gmt":"2026-05-07T16:23:57","slug":"evalon-cream","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/evalon-cream\/","title":{"rendered":"Evalon Cream"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background: #fff8e1; border-left: 4px solid #f5a623; padding: 18px 22px; margin: 18px 0; border-radius: 4px;\">\n<p style=\"margin: 0 0 8px 0;\"><strong>\ud83d\udca1 \u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u0391\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7<\/strong><\/p>\n<p style=\"margin: 0;\"><strong>Evalon Cream<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>vaginal estriol 1 mg\/g cream<\/strong> \u03b3\u03b9\u03b1 <strong>genitourinary syndrome of menopause<\/strong> (vaginal dryness, dyspareunia, recurrent UTIs, vulvar irritation). Estriol is the weakest natural estrogen \u2014 minimal systemic absorption, so concomitant progestin is generally not required even in women with an intact uterus. First-line local therapy for postmenopausal GSM with a favourable safety profile.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background: #f4f8fb; border: 1px solid #d8e3eb; padding: 12px 16px; margin: 16px 0; border-radius: 4px; font-size: 14px;\"><strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size: 14px; color: #444; margin: 8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Our generic medications are sourced from WHO-GMP certified manufacturers and shipped worldwide in discreet, plain packaging \u2014 no medication name on the parcel exterior. Card payments are routed through a regulated processor (statement descriptors include a regulated card-payment processor \u2014 never \u201cMedsBase\u201d or any medication name). Crypto and SEPA bank transfer are also accepted. Every order is backed by our Reshipment Assurance Policy.<\/p>\n<div style=\"background: #f4f8fb; border-left: 4px solid #2c7cb0; padding: 14px 20px; margin: 16px 0; border-radius: 4px; font-size: 0.95em;\"><strong>\ud83d\udd12 \u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03b1\u03b3\u03bf\u03c1\u03ac\u03c3\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd MedsBase:<\/strong> \u0395\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b3\u03bd\u03ae\u03c3\u03b9\u03b1 \u03c0\u03c1\u03bf\u03bc\u03ae\u03b8\u03b5\u03b9\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 \u0391\u03c3\u03c6\u03b1\u03bb\u03ae\u03c2 \u03bf\u03bb\u03bf\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03b1\u03b3\u03bf\u03c1\u03ac\u03c2 (\u03c0\u03b9\u03c3\u03c4\u03c9\u03c4\u03b9\u03ba\u03ae \u03ba\u03ac\u03c1\u03c4\u03b1, \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1) \u00b7 \u0392\u03b1\u03b8\u03bc\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 4.9\u2605 \u03b1\u03c0\u03cc 1,400+ \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2<\/div>\n<h2><strong>What Is Evalon Cream?<\/strong><\/h2>\n<p>Evalon Cream is a <strong>vaginal estriol cream 1 mg\/g<\/strong>, containing the weakest of the three natural estrogens (estriol, estradiol, estrone). Estriol&#8217;s weak potency combined with local application minimises systemic absorption, making it well-suited to genitourinary syndrome of menopause without meaningful systemic estrogenic effects at standard doses. Manufactured by Zydus Cadila.<\/p>\n<h2><strong>\u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u0395\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ad\u03c2<\/strong><\/h2>\n<ul>\n<li><strong>Genitourinary syndrome of menopause (GSM):<\/strong> vaginal dryness, dyspareunia, itching, recurrent urinary tract infections related to vulvar atrophy.<\/li>\n<li><strong>Atrophic vulvovaginitis<\/strong> in premature ovarian insufficiency.<\/li>\n<li><strong>Postmenopausal recurrent UTI prophylaxis<\/strong> \u2014 reduces UTI frequency ~50%.<\/li>\n<li><strong>Post-oophorectomy or post-radiation pelvic atrophy.<\/strong><\/li>\n<\/ul>\n<h2><strong>\u03a0\u03ce\u03c2 \u03bd\u03b1 \u0395\u03c6\u03b1\u03c1\u03bc\u03cc\u03c3\u03b5\u03c4\u03b5<\/strong><\/h2>\n<ol>\n<li>Wash hands. Attach the applicator to the tube; fill to the prescribed mark.<\/li>\n<li><strong>Initial phase (2\u20133 weeks):<\/strong> apply 1 g nightly at bedtime.<\/li>\n<li><strong>\u03a3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7:<\/strong> <strong>2\u20133 times per week<\/strong> (e.g. Monday, Wednesday, Friday).<\/li>\n<li>Apply a small amount externally to the vulva and vestibule if external symptoms are prominent.<\/li>\n<li>Wash the applicator with warm soapy water after each use.<\/li>\n<li>Avoid applying immediately before intercourse (partner absorption minor but best avoided).<\/li>\n<\/ol>\n<h2><strong>Safety and Progestin Question<\/strong><\/h2>\n<p>Estriol&#8217;s weak binding and short action means systemic exposure at standard vaginal doses is low. <strong>Concomitant progestin is generally not required<\/strong> \u2014 even in women with an intact uterus \u2014 because endometrial stimulation at standard doses is minimal. For women on high-dose or prolonged continuous use, endometrial monitoring may be discussed with a clinician.<\/p>\n<h2><strong>\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/strong><\/h2>\n<p><strong>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> transient local itch or burning on first applications, small amount of vaginal discharge, breast tenderness (mild, rare).<\/p>\n<p><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> mood changes, headache, leucorrhoea.<\/p>\n<p><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1:<\/strong> unexpected vaginal bleeding (investigate).<\/p>\n<h2><strong>Who Should Not Use Evalon Cream<\/strong><\/h2>\n<ul>\n<li>Current or history of estrogen-dependent cancer (breast, endometrial) \u2014 discuss individualised risk-benefit with oncologist<\/li>\n<li>Undiagnosed vaginal bleeding<\/li>\n<li>Known hypersensitivity to estriol<\/li>\n<li>Active thromboembolic disease (less concerning than oral HRT, but discuss)<\/li>\n<\/ul>\n<h2><strong>Estriol vs Estradiol Vaginal Products<\/strong><\/h2>\n<p>Both work for GSM. Estriol is the weaker of the two, with even less systemic absorption \u2014 potentially a better choice for women with breast cancer history or VTE concerns (after oncologist review). Estradiol products may give slightly faster symptomatic relief but with marginally higher systemic exposure. Both need clinical selection.<\/p>\n<h2><strong>\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/strong><\/h2>\n<p>Store at room temperature (15\u201325 \u00b0C), away from heat. Replace cap after use. Keep out of reach of children.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">How quickly will I feel relief?<\/h3>\n<p>Vaginal pH and lubrication improve within 2\u20134 weeks. Pain with intercourse typically improves by 6\u201312 weeks. Full response can take 3 months.<\/p>\n<h3 class=\"wp-block-heading\">Do I need to take a progestin with Evalon Cream?<\/h3>\n<p>Usually no \u2014 estriol&#8217;s weak systemic absorption at standard doses does not require endometrial protection. High-dose or prolonged continuous use is a grey area \u2014 discuss with clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Evalon Cream if I had breast cancer?<\/h3>\n<p>Discuss with your oncologist. Low-dose vaginal estriol is often considered when significant GSM symptoms persist despite non-hormonal measures. Some oncologists permit it; others prefer non-estrogenic options (ospemifene, vaginal DHEA, moisturisers).<\/p>\n<h3 class=\"wp-block-heading\">Can I have sex after applying the cream?<\/h3>\n<p>Avoid immediately after application. Apply on non-intercourse nights, or wait 8\u201310 hours. Partner absorption is minor.<\/p>\n<h3 class=\"wp-block-heading\">What if I still have symptoms after 3 months?<\/h3>\n<p>Consider longer trial, higher dose, or switch to estradiol vaginal product. Non-estrogen options (ospemifene, DHEA pessaries, vaginal CO2 laser) are also available. Discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Is estriol safer than estradiol?<\/h3>\n<p>Estriol has lower systemic absorption at standard doses. For women with elevated concerns about estrogen exposure (breast cancer history, VTE risk), estriol is often preferred.<\/p>\n<h3 class=\"wp-block-heading\">Can Evalon Cream reduce my UTI frequency?<\/h3>\n<p>Yes \u2014 postmenopausal recurrent UTIs respond to vaginal estrogen, with ~50% reduction in studies. Vaginal estrogen restores protective lactobacilli and healthy pH.<\/p>\n<h3 class=\"wp-block-heading\">Is Evalon Cream OK for long-term use?<\/h3>\n<p>Years of continuous low-dose vaginal estriol have a strong safety record. Annual clinical review; endometrial monitoring generally not required unless on high-dose or bleeding occurs.<\/p>\n<h3 class=\"wp-block-heading\">Related Women&#8217;s Health Products<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/tamodex\/\">Tamodex (Tamoxifen 10 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tamilong\/\">Tamilong (Tamoxifen 20 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/letroheal\/\">Letroheal (Letrozole 2.5 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/etibo\/\">Etibo (Lapatinib 250 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/duphaston\/\">Duphaston (Dydrogesterone 10 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/deviry\/\">Deviry (Medroxyprogesterone 10 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/naprosyn\/\">Naprosyn (Naproxen 250 mg)<\/a><\/li>\n<\/ul>\n<div style=\"background: #fff3f3; border-left: 4px solid #d9534f; padding: 14px 20px; margin: 16px 0; border-radius: 4px; font-size: 0.9em;\">\n<p style=\"margin: 0;\"><strong>\u2695\ufe0f \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u0391\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u0395\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd:<\/strong> Information is educational and does not replace medical advice. Consult a clinician before starting, stopping, or changing any medication, particularly for cancer therapy, hormonal treatments, and prescription products.<\/p>\n<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 <strong>\u03a5\u03b3\u03b5\u03af\u03b1 \u0393\u03c5\u03bd\u03b1\u03b9\u03ba\u03ce\u03bd<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/cabgolin\/\">Cabgolin<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/cystopen\/\">Cystopen<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/danogen\/\">Danogen<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/primolut-n\/\">Primolut-N<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/premarin-cream\/\">Premarin Cream<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Relieves vaginal dryness<br \/>\n\u2705 Restores vaginal elasticity<br \/>\n\u2705 Alleviates menopausal symptoms<br \/>\n\u2705 Promotes tissue repair<br \/>\n\u2705 Enhances intimate comfort<\/p>\n<p>Evalon Cream contains <strong>Estriol<\/strong>.<\/p>","protected":false},"featured_media":52870,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3141,3538,3502],"product_tag":[3539,3540],"class_list":{"0":"post-52869","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-vaginal-dryness-treatment","8":"product_cat-womens-health","9":"product_tag-estriol","10":"product_tag-estriol-cream","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/52869","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=52869"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/52870"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=52869"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=52869"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=52869"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=52869"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}