<\/p>\n
Mesacol<\/strong> \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 mesalamine<\/strong> (also called mesalazine or 5-aminosalicylic acid, 5-ASA) — a topical intestinal anti-inflammatory drug<\/strong> \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 treat ulcerative colitis (UC) and maintain remission<\/strong>. It acts locally<\/em> in the colon lining, suppressing the inflammatory pathways that drive UC flares. \u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc:<\/strong> mesalamine is not a treatment for irritable bowel syndrome (IBS)<\/strong>. UC is a chronic inflammatory disease (IBD); IBS is a functional disorder with no bowel inflammation — different conditions, different drugs. For UC, mesalamine is first-line therapy in mild-to-moderate disease. Typical dose: 400 mg or 800 mg; see dosing section. Once daily (OD\/MMX) or divided doses depending on formulation. Side effects are usually mild — headache, nausea, abdominal discomfort; rare renal effects warrant periodic kidney-function checks.<\/p>\n<\/div>\n \ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n \u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n Mesacol is an oral aminosalicylate (5-ASA)<\/strong> medicine containing mesalamine<\/strong> (400 mg or 800 mg), supplied as delayed-release Eudragit-S enteric-coated tablets. Manufactured by Sun Pharma in packs of 30, 60, 90 or 180 tablets. Mesalamine is the active metabolite of older sulfasalazine — without the sulfapyridine moiety that caused most of sulfasalazine’s systemic side effects.<\/p>\n Mesalamine has been a first-line therapy for mild-to-moderate ulcerative colitis<\/strong> since the 1980s and is recommended as induction and maintenance therapy by ACG, ECCO, and BSG guidelines. The original mesalamine brand Asacol was approved in 1987; today there are several delivery systems (Eudragit-coated, ethylcellulose microgranule, MMX multi-matrix) each designed to release mesalamine at a different point in the gastrointestinal tract.<\/p>\n Mesacol is \u03b4\u03b5\u03bd<\/strong> a treatment for:<\/p>\n Mesalamine is a topical intestinal anti-inflammatory. Its exact mechanism is multifactorial, involving several anti-inflammatory pathways in the colonic mucosa:<\/p>\n Because mesalamine’s target is the colonic mucosa, delivery is critical. The delayed-release Eudragit-S enteric-coated tablets of Mesacol is designed to release active drug in the colon rather than being absorbed prematurely in the small intestine. Eudragit-S coating dissolves at pH ≥ 7 (terminal ileum\/colon); Eudragit-L at pH ≥ 6 (duodenum\/jejunum); ethylcellulose microgranules release continuously; MMX uses a lipophilic\/hydrophilic matrix for controlled colonic release.<\/p>\n Induction of remission in mild-to-moderate UC:<\/strong> 2.4–4.8 g\/day in divided doses. Maintenance of remission:<\/strong> 1.6–2.4 g\/day.<\/p>\n Mesalamine is usually well-tolerated compared with sulfasalazine and immunomodulators.<\/p>\n \u03a3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong><\/p>\n \u03a3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac:<\/strong><\/p>\n Store Mesacol below 25°C in a dry place, in the original blister. Keep out of reach of children. Protect from light and moisture.<\/p>\n Yes — all three names refer to the same molecule (5-aminosalicylic acid). Mesalamine is the US adopted name (USAN); mesalazine is the international non-proprietary name (INN); 5-ASA is the chemical abbreviation. Different brands and regions label it differently.<\/p>\n No — mesalamine does not treat IBS. IBS is a functional disorder; there is no mucosal inflammation for mesalamine to work on. For IBS, first-line treatments are dietary changes (low-FODMAP diet, fibre modification), antispasmodics like mebeverine (Colospa) or hyoscine, and — for IBS-D specifically — short courses of rifaximin (Rifagut). Central modulators (low-dose amitriptyline) are used for refractory IBS pain.<\/p>\n Symptom improvement typically begins within 1–2 weeks; full remission in 4–8 weeks at induction doses. Stool frequency and urgency usually improve first, followed by abdominal pain and finally mucosal healing (visible on colonoscopy at 8–12 weeks).<\/p>\n Most patients with ulcerative colitis need long-term maintenance mesalamine to stay in remission — typically at least 1.6–2.4 g\/day. Stopping after remission is achieved leads to relapse within 6–12 months in most studies. Mesalamine is safe for decades of use when renal function is monitored.<\/p>\n Several mesalamine formulations (particularly MMX “ghost” tablets) pass through largely intact in the stool. This is \u03b1\u03bd\u03b1\u03bc\u03b5\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7<\/em> and the drug has been released inside the colon as designed. If you see the tablet unchanged with no coating damage, check your technique; otherwise no action is needed.<\/p>\n Short paracetamol (acetaminophen) is preferred for pain in UC. Chronic NSAID use can both precipitate UC flares \u03ba\u03b1\u03b9<\/em> increase the renal risk of mesalamine — avoid where possible. Occasional use is usually tolerated.<\/p>\n You can order Mesacol (400 mg or 800 mg) from MedsBase in packs of 30, 60, 90 or 180 tablets. We ship worldwide with discreet packaging and genuine WHO-GMP certified manufacturer stock.<\/p>\n Mesacol is supplied from a \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong>. Every order ships discreetly worldwide and is covered by our \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> — if it does not arrive within 20 business days, we reship at no cost. Mesalamine 400 mg delayed-release is the WHO-recommended first-line for ulcerative colitis induction and maintenance — topical action with minimal systemic exposure.<\/p>\n <\/p>\n Mesacol contains Mesalamine<\/span><\/p>","protected":false},"featured_media":52990,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3542,3342,3565],"product_tag":[3566],"class_list":{"0":"post-52989","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-gastro-health","9":"product_cat-general-health","10":"product_cat-irritable-bowel-syndrome-ibs-treatment","11":"product_tag-mesalamine","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/52989","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=52989"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/52990"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=52989"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=52989"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=52989"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=52989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n
What Is Mesacol?<\/h2>\n
What Is Mesacol Used For?<\/h2>\n
\n
\n
How Does Mesacol Work?<\/h2>\n
\n
\u0394\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03a7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7<\/h2>\n
\n
\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n
\n
\n
\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n
\n
Who Should Not Take Mesacol?<\/h2>\n
\n
\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n
\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n
Is mesalamine the same as mesalazine or 5-ASA?<\/h3>\n
Can I take Mesacol for IBS or general bloating?<\/h3>\n
How long until Mesacol works?<\/h3>\n
Do I need to take Mesacol forever?<\/h3>\n
Why am I seeing intact tablet shells in my stool?<\/h3>\n
Can I take aspirin or NSAIDs with Mesacol?<\/h3>\n
Where can I buy Mesacol online?<\/h3>\n
Related IBS & IBD Medications<\/h2>\n
\n
\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n
Other Gastro Health Medications<\/h3>\n
\n
\u2705 Treats Inflammatory Bowel Disease
\n\u2705 Reduces Intestinal Inflammation
\n\u2705 Relieves Abdominal Pain
\n\u2705 Improves Digestive Health<\/h5>\n