{"id":53742,"date":"2023-09-20T09:50:03","date_gmt":"2023-09-20T09:50:03","guid":{"rendered":"https:\/\/medsname.com\/eliquis\/"},"modified":"2026-05-01T10:49:12","modified_gmt":"2026-05-01T10:49:12","slug":"eliquis","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/eliquis\/","title":{"rendered":"Eliquis"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Eliquis?<\/h3>\n<p style=\"margin:0;\"><strong>Eliquis<\/strong> is 2.5 \/ 5 mg apixaban tablets from Bristol-Myers Squibb \/ Pfizer &mdash; a direct oral anticoagulant (DOAC) and direct factor Xa inhibitor. Apixaban was approved by the FDA in 2012 after the ARISTOTLE (AF), AVERROES (aspirin-intolerant AF), AMPLIFY (VTE) and ADVANCE (orthopaedic prophylaxis) trials. Among the DOACs, apixaban has the lowest GI bleeding risk and is generally preferred in older patients, those with renal impairment, and those at higher GI bleeding risk. Standard dose: <strong>5 mg twice daily<\/strong> in non-valvular AF, reduced to <strong>2.5 mg twice daily<\/strong> if at least two of: age &ge;80 years, body weight &le;60 kg, or serum creatinine &ge;1.5 mg\/dL. <strong>VTE treatment:<\/strong> 10 mg twice daily for 7 days, then 5 mg twice daily; extended prophylaxis 2.5 mg twice daily after 6 months. No routine blood monitoring. Reversal: andexanet alfa (specific antidote) where available, or 4-factor prothrombin complex concentrate. Specialist or family-physician supervision is standard.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<h2 class=\"wp-block-heading\">What Is Eliquis?<\/h2>\n<p>Eliquis is 2.5 \/ 5 mg apixaban tablets from Bristol-Myers Squibb \/ Pfizer, supplied in 10-180 tablets. Apixaban was approved by the FDA in 2012 and is the most widely prescribed DOAC in many markets. ARISTOTLE (2011) showed superiority over warfarin for stroke prevention in AF with less major and intracranial bleeding; AMPLIFY (2013) showed non-inferiority to enoxaparin\/warfarin for VTE treatment with less major bleeding.<\/p>\n<h2 class=\"wp-block-heading\">How Apixaban Works<\/h2>\n<p>Apixaban directly and reversibly inhibits factor Xa, the central convergence point of the intrinsic and extrinsic coagulation cascades, reducing thrombin generation and clot formation. Half-life is approximately 12 hours; about 27% renally cleared, the rest hepatic and biliary. Twice-daily dosing maintains stable anticoagulation.<\/p>\n<h2 class=\"wp-block-heading\">\u0395\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Non-valvular atrial fibrillation<\/strong> &mdash; stroke and systemic embolism prevention (ARISTOTLE)<\/li>\n<li><strong>Acute venous thromboembolism (DVT and PE)<\/strong> &mdash; treatment (AMPLIFY)<\/li>\n<li><strong>Extended VTE secondary prevention<\/strong> &mdash; after 6+ months of treatment (AMPLIFY-EXT)<\/li>\n<li><strong>VTE prophylaxis after major orthopaedic surgery<\/strong> &mdash; total hip \/ knee replacement (ADVANCE)<\/li>\n<li><strong>Aspirin-intolerant AF stroke prevention<\/strong> (AVERROES) &mdash; superior to aspirin without increased major bleeding<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0394\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:0 0 22px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th style=\"padding:8px;text-align:left;\">\u0394\u03cc\u03c3\u03b7<\/th>\n<th style=\"padding:8px;text-align:left;\">\u03a3\u03b7\u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9\u03c2<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;\">Non-valvular AF<\/td>\n<td style=\"padding:8px;\">5 mg twice daily<\/td>\n<td style=\"padding:8px;\">Reduce to 2.5 mg BID if &ge;2 of: age &ge;80, weight &le;60 kg, Cr &ge;1.5 mg\/dL<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;\">VTE treatment<\/td>\n<td style=\"padding:8px;\">10 mg BID &times; 7 days, then 5 mg BID<\/td>\n<td style=\"padding:8px;\">Total duration 3-6 months minimum<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;\">Extended VTE prophylaxis<\/td>\n<td style=\"padding:8px;\">2.5 mg BID<\/td>\n<td style=\"padding:8px;\">After 6 months of treatment course<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;\">Hip replacement prophylaxis<\/td>\n<td style=\"padding:8px;\">2.5 mg BID &times; 35 days<\/td>\n<td style=\"padding:8px;\">Start 12-24 hours post-op<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;\">Knee replacement prophylaxis<\/td>\n<td style=\"padding:8px;\">2.5 mg BID &times; 12 days<\/td>\n<td style=\"padding:8px;\">Start 12-24 hours post-op<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Take with or without food. If a dose is missed, take it as soon as possible the same day, then resume the normal twice-daily schedule &mdash; do not double up.<\/p>\n<h2 class=\"wp-block-heading\">\u039a\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u0391\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/h2>\n<p>No routine blood monitoring required &mdash; a major practical advantage over warfarin. Check baseline FBC, renal and hepatic function. Recheck renal function at 3-12 month intervals depending on baseline CrCl, age, and acute illness. Apixaban has the lowest GI bleeding rate of the available DOACs. Major bleeding ~2-3%\/year in AF. Watch for melaena, haematemesis, fresh rectal bleeding, haematuria, intracranial bleed symptoms, unexplained anaemia, or unusually heavy menstrual loss.<\/p>\n<h2 class=\"wp-block-heading\">\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li>Major bleeding (~2-3%\/year in AF, lower than warfarin)<\/li>\n<li>Minor bleeding: epistaxis, gum bleeding, bruising, menorrhagia<\/li>\n<li>\u0391\u03bd\u03b1\u03b9\u03bc\u03af\u03b1<\/li>\n<li>\u039d\u03b1\u03c5\u03c4\u03af\u03b1<\/li>\n<li>Hypersensitivity reactions, rare<\/li>\n<li>Hepatotoxicity, rare<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li>Active pathological bleeding<\/li>\n<li>Mechanical heart valve (use warfarin &mdash; RE-ALIGN)<\/li>\n<li>Moderate-to-severe (rheumatic) mitral stenosis (use warfarin)<\/li>\n<li>Antiphospholipid syndrome, especially triple-positive (use warfarin &mdash; TRAPS)<\/li>\n<li>\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 (Child-Pugh B \u03ae C)<\/li>\n<li>End-stage renal failure (CrCl &lt;15 mL\/min) or dialysis &mdash; limited evidence<\/li>\n<li>Concurrent strong dual CYP3A4 + P-gp inhibitors (azole antifungals, HIV protease inhibitors)<\/li>\n<li>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03b8\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<ul>\n<li><strong>Strong CYP3A4 + P-gp dual inhibitors<\/strong> (ketoconazole, itraconazole, ritonavir, clarithromycin) &mdash; substantially raise apixaban levels; contraindicated.<\/li>\n<li><strong>Strong CYP3A4 + P-gp inducers<\/strong> (rifampicin, phenytoin, carbamazepine, St John&rsquo;s wort) &mdash; lower levels; avoid or use alternative.<\/li>\n<li><strong>Other anticoagulants and antiplatelets<\/strong> (warfarin, DOACs, heparins, aspirin, clopidogrel, NSAIDs) &mdash; additive bleeding risk; combine only when clinically indicated.<\/li>\n<li><strong>SSRIs\/SNRIs<\/strong> &mdash; modest additive bleeding risk via platelet serotonin depletion.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Reversal of Anticoagulation<\/h2>\n<p>For major bleeding or urgent surgery, andexanet alfa is the specific reversal agent. Where unavailable, 4-factor prothrombin complex concentrate (4F-PCC, 50 IU\/kg) is used. Activated charcoal within 2 hours of ingestion may be considered. Apixaban has high protein binding so dialysis is not effective.<\/p>\n<h2 class=\"wp-block-heading\">Surgery and Dental Procedures<\/h2>\n<p>For most surgery, stop apixaban <strong>24-48 hours<\/strong> before depending on bleeding risk and renal function (longer for major surgery or impaired renal function). Most simple dental procedures can be done without stopping. Resume 24 hours after low-risk surgery and 48-72 hours after high-risk surgery once haemostasis is secured. Bridging is generally not required.<\/p>\n<h2 class=\"wp-block-heading\">Pregnancy and Breastfeeding<\/h2>\n<p>Pregnancy: contraindicated &mdash; crosses placenta; use LMWH. Breastfeeding: avoid &mdash; transfer to milk likely.<\/p>\n<h2 class=\"wp-block-heading\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>Store Eliquis below 25&deg;C in the original blister pack. Keep out of reach of children.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">Do I need blood tests on Eliquis?<\/h3>\n<p>No routine test for efficacy. Check renal and hepatic function at baseline and at 3-12 month intervals depending on age, baseline CrCl, and acute illness.<\/p>\n<h3 class=\"wp-block-heading\">Why is apixaban dosed twice daily?<\/h3>\n<p>Apixaban has a 12-hour half-life; twice-daily dosing maintains more stable anticoagulation than once-daily alternatives. The trade-off is one extra daily dose for arguably the cleanest bleeding profile of the DOACs.<\/p>\n<h3 class=\"wp-block-heading\">Why does the dose drop to 2.5 mg twice daily for some patients?<\/h3>\n<p>In non-valvular AF, dose-reduce to 2.5 mg BID if any two of: age &ge;80 years, body weight &le;60 kg, or serum creatinine &ge;1.5 mg\/dL (133 micromol\/L). This avoids excessive drug accumulation and bleeding risk in the most vulnerable patients.<\/p>\n<h3 class=\"wp-block-heading\">\u03a4\u03b9 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd \u03c7\u03ac\u03c3\u03c9 \u03bc\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7;<\/h3>\n<p>Take it as soon as possible the same day, then resume the normal twice-daily schedule. If you miss two consecutive doses or skip a whole day, do not double up &mdash; resume the normal schedule and contact your prescriber for advice.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Eliquis for a mechanical heart valve?<\/h3>\n<p>No. The RE-ALIGN trial showed DOACs (dabigatran) caused more thromboembolic and bleeding events than warfarin in mechanical valve patients. Warfarin is the only acceptable oral anticoagulant for mechanical valves and rheumatic mitral stenosis.<\/p>\n<h3 class=\"wp-block-heading\">Can I switch from warfarin to Eliquis?<\/h3>\n<p>Yes &mdash; in non-valvular AF and most VTE indications. Stop warfarin, check the INR, and start apixaban once the INR is &lt;2.0. Speak with your anticoagulation clinic before switching.<\/p>\n<h3 class=\"wp-block-heading\">What if I cut myself while on Eliquis?<\/h3>\n<p>Apply firm direct pressure for 15-20 minutes. Most minor cuts stop normally. Bleeding that continues &gt;20 minutes, black or bloody stools, blood in urine, unusual bruising, severe headache, or unexplained heavy menstrual bleeding warrant urgent medical review.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Eliquis in pregnancy?<\/h3>\n<p>No &mdash; DOACs are contraindicated in pregnancy and breastfeeding. LMWH is the anticoagulant of choice in pregnancy.<\/p>\n<h3 class=\"wp-block-heading\">\u03a4\u03b9 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03ce \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b5\u03af\u03bf;<\/h3>\n<p>Inform your surgeon and anticoagulation clinic well in advance. Apixaban is typically stopped 24-48 hours before surgery depending on bleeding risk and renal function. Bridging with heparin is usually not required.<\/p>\n<h3 class=\"wp-block-heading\">Where can I buy Eliquis online?<\/h3>\n<p>You can buy Eliquis (2.5 \/ 5 mg apixaban, 10-180 tablets) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n<h2 class=\"wp-block-heading\">Other Anti-Coagulants and Antiplatelets<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/warf\/\">Warf &mdash; Warfarin 1\/2\/5 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/waf-5\/\">Waf-5 &mdash; Warfarin 5 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/uniwarfin\/\">Uniwarfin &mdash; Warfarin 5 mg (Unichem)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/xarelto-20\/\">Xarelto 20 &mdash; Rivaroxaban 20 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/plavix\/\">Plavix &mdash; Clopidogrel 75 mg (Sanofi)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/deplatt\/\">Deplatt &mdash; Clopidogrel 75 mg (Torrent)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/anti-coagulants\/\"><strong>Browse all Anti-Coagulants &amp; Antiplatelets<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u0391\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u0395\u03c5\u03b8\u03cd\u03bd\u03b7\u03c2.<\/strong> Direct oral anticoagulants require diagnosis, indication review and bleeding-risk assessment by a doctor. Apixaban is not appropriate for mechanical heart valves, rheumatic mitral stenosis, or triple-positive antiphospholipid syndrome &mdash; use warfarin instead. Always discuss any change in dose, course duration, or planned surgery with your prescriber.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 <strong>\u0393\u03b5\u03bd\u03b9\u03ba\u03ae \u03a5\u03b3\u03b5\u03af\u03b1<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/mozep\/\">Mozep<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tritin\/\">Tritin<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/pilocar-eye-drop\/\">Pilocar Eye Drop<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/oflotas\/\">Oflotas<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/aceret\/\">Aceret<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Prevents blood clots<br \/>\n\u2705 Reduces stroke risk<br \/>\n\u2705 Minimizes DVT occurrence<br \/>\n\u2705 Manages atrial fibrillation<br \/>\n\u2705 Decreases embolism risk<\/p>\n<p>Eliquis contains Apixaban.<\/p>","protected":false},"featured_media":53743,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3635,3141,3342],"product_tag":[3636,3637],"class_list":{"0":"post-53742","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-coagulants","7":"product_cat-category-overview","8":"product_cat-general-health","9":"product_tag-apixaban","10":"product_tag-eliquis","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/53742","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=53742"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/53743"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=53742"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=53742"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=53742"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=53742"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}