\n<\/p>\n
Deplatt<\/strong> is 75 mg clopidogrel tablets from Torrent Pharma — an oral antiplatelet agent in the thienopyridine class. Clopidogrel is an irreversible P2Y12 ADP-receptor antagonist that reduces platelet aggregation. It is a CYP2C19-activated prodrug, half-life of the active metabolite is short but platelet inhibition persists for the platelet’s 7-10 day lifespan. Standard dose is 75 mg once daily, with a 300-600 mg loading dose in acute coronary syndrome and post-PCI. Used as monotherapy for secondary stroke\/TIA and peripheral arterial disease, and as part of dual antiplatelet therapy (DAPT, with low-dose aspirin) for 6-12 months after acute coronary syndrome or coronary stenting. Major bleeding risk ~1-3%\/year as monotherapy, higher on DAPT. Clopidogrel selection is individualised by indication, bleeding risk, CYP2C19 metaboliser status, and concurrent medication. Specialist or family-physician supervision is standard.<\/p>\n<\/div>\n \ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n \u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n Deplatt is 75 mg clopidogrel tablets from Torrent Pharma, supplied in 30-90 tablets. Clopidogrel was approved by the FDA in 1997 and is the most widely used P2Y12 inhibitor worldwide. Landmark trials — CAPRIE<\/strong> (1996, secondary prevention vs aspirin), CURE<\/strong> (2001, ACS without ST elevation), CLARITY\/COMMIT<\/strong> (2005, STEMI) and PCI-CURE<\/strong> — established its role in atherothrombotic disease.<\/p>\n Clopidogrel is a prodrug that requires two-step hepatic activation by CYP2C19 (and to a lesser extent CYP3A4, CYP1A2, CYP2B6) to its active thiol metabolite. The active metabolite irreversibly binds the platelet P2Y12 receptor, blocking ADP-mediated platelet activation and aggregation. Inhibition lasts the lifespan of the affected platelet (7-10 days), so platelet function recovers gradually as new platelets are produced.<\/p>\n \u03a3\u03c5\u03bd\u03c4\u03ae\u03c1\u03b7\u03c3\u03b7:<\/strong> 75 mg once daily, with or without food. ACS \/ PCI loading:<\/strong> 300 mg (often 600 mg in primary PCI) loading dose followed by 75 mg daily. Stroke\/TIA:<\/strong> 75 mg daily as monotherapy; short-course 21-day DAPT with aspirin in minor stroke\/high-risk TIA per CHANCE\/POINT then continue clopidogrel monotherapy. Duration of DAPT after stenting is determined by the cardiologist based on stent type, indication and bleeding risk.<\/p>\n Around 30% of East Asians and 2-15% of Caucasians carry CYP2C19 loss-of-function alleles (*2, *3) that reduce clopidogrel activation and increase ischaemic event rates after PCI. Where genotyping or platelet-function testing identifies poor or intermediate metabolisers, alternative P2Y12 inhibitors (ticagrelor, prasugrel) are typically preferred.<\/p>\n Major bleeding rate is roughly 1-3%\/year on monotherapy and higher on DAPT. No routine blood test is needed for efficacy. Monitor for bruising, epistaxis, gum bleeding, GI bleeding (melaena, haematemesis, fresh rectal blood), haematuria, or unusually heavy menstrual bleeding. Baseline FBC, renal and hepatic function are sensible. Co-prescribed PPI (preferably pantoprazole or rabeprazole) is recommended in patients at increased GI bleeding risk.<\/p>\n Stop clopidogrel 5-7 days<\/strong> before elective surgery with significant bleeding risk. Most simple dental work can be done without stopping. Never stop clopidogrel within the protected DAPT window after coronary stenting without cardiology advice — premature discontinuation is a major cause of in-stent thrombosis and MI.<\/p>\n Pregnancy: limited human data. Use only when benefit clearly outweighs risk; specialist input required. Breastfeeding: avoid — transfer to milk likely.<\/p>\n Store Deplatt below 25°C in the original blister pack. Keep out of reach of children.<\/p>\n No routine test is needed for efficacy. Baseline FBC, renal and hepatic function are sensible. Genotyping or platelet-function testing is reserved for select cardiology cases.<\/p>\n Yes — the clopidogrel + aspirin combination (DAPT) is the standard regimen for 6-12 months after acute coronary syndrome or coronary stenting. Duration is set by your cardiologist.<\/p>\n If you remember within 12 hours, take the missed dose. Otherwise skip and resume the next day — do not double up.<\/p>\n Apply firm direct pressure for 15-20 minutes for cuts. Bruising is common. Bleeding that continues >20 minutes or bleeds through dressings, black stools, blood in urine, or unexplained heavy menstrual bleeding warrants urgent medical review.<\/p>\n Omeprazole and esomeprazole reduce clopidogrel activation and are best avoided. If a PPI is needed for stomach protection, pantoprazole or rabeprazole are preferred.<\/p>\n Inform your surgeon and cardiologist well in advance. Clopidogrel is typically stopped 5-7 days before elective procedures with significant bleeding risk — but never stop without cardiology input if you have a recent coronary stent.<\/p>\n Both contain the same active ingredient, clopidogrel 75 mg. Brand-name Plavix is made by Sanofi\/BMS; Deplatt is the Torrent Pharma brand. The two are bioequivalent generics of the same molecule.<\/p>\n Moderate alcohol is acceptable. Heavy or binge drinking raises GI bleeding risk and is best avoided.<\/p>\n Indefinitely for secondary stroke\/TIA or PAD. After ACS or stenting the DAPT phase is typically 6-12 months, then often clopidogrel monotherapy continues indefinitely if aspirin-intolerant. Your cardiologist sets the duration.<\/p>\n You can buy Deplatt (75 mg clopidogrel, 30-90 tablets) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n \u2705 Prevents blood clots\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n
What Is Deplatt?<\/h2>\n
How Clopidogrel Works<\/h2>\n
\u0395\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n
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\u0394\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1<\/h2>\n
CYP2C19 Genetic Variation<\/h2>\n
\u039a\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u0391\u03b9\u03bc\u03bf\u03c1\u03c1\u03b1\u03b3\u03af\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7<\/h2>\n
\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n
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\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n
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\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n
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Surgery and Dental Procedures<\/h2>\n
Pregnancy and Breastfeeding<\/h2>\n
\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n
\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n
Do I need blood tests on Deplatt?<\/h3>\n
Can I take Deplatt with aspirin?<\/h3>\n
What if I miss a dose of Deplatt?<\/h3>\n
What should I do if I cut myself or bruise easily?<\/h3>\n
Can I take Deplatt with omeprazole?<\/h3>\n
\u03a4\u03b9 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03b1\u03c3\u03c4\u03ce \u03c7\u03b5\u03b9\u03c1\u03bf\u03c5\u03c1\u03b3\u03b5\u03af\u03bf;<\/h3>\n
Is Deplatt the same as Plavix?<\/h3>\n
Can I drink alcohol on Deplatt?<\/h3>\n
How long do I take Deplatt?<\/h3>\n
Where can I buy Deplatt online?<\/h3>\n
Other Anti-Coagulants and Antiplatelets<\/h2>\n
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\n\u2705 Reduces stroke risk
\n\u2705 Manages heart diseases
\n\u2705 Controls chest pain
\n\u2705 Improves blood flow<\/p>","protected":false},"featured_media":53753,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3635,3141,3342],"product_tag":[],"class_list":{"0":"post-53752","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-coagulants","7":"product_cat-category-overview","8":"product_cat-general-health","10":"first","11":"outofstock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/53752","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=53752"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/53753"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=53752"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=53752"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=53752"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=53752"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}