{"id":54146,"date":"2023-09-20T09:55:08","date_gmt":"2023-09-20T09:55:08","guid":{"rendered":"https:\/\/medsname.com\/tretin-cream\/"},"modified":"2026-04-30T10:25:02","modified_gmt":"2026-04-30T10:25:02","slug":"tretin-cream","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/tretin-cream\/","title":{"rendered":"Tretin Cream"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:20px 0;border-radius:6px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:1.15em;\">\ud83d\udca1 Quick Answer \u2014 What is Tretin Cream?<\/h3>\n<p style=\"margin:0;\"><strong>Tretin Cream<\/strong> contains tretinoin 0.025% or 0.05% \u2014 a topical retinoid (vitamin A derivative) for mild-to-moderate acne vulgaris, photoageing (fine lines, uneven tone), and post-inflammatory hyperpigmentation. Apply a pea-sized amount at bedtime to clean dry skin. Start 2\u20133 nights per week for the first 2 weeks; increase frequency as the skin acclimates. Use SPF 30+ daily. Visible improvement takes 8\u201312 weeks. Initial flare (&#8220;retinoid purge&#8221;) at weeks 2\u20134 is normal \u2014 do not stop unless severe.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:6px;font-size:0.95em;\">\n<strong>\ud83c\udfed WHO-GMP certified manufacturer<\/strong> \u00b7 <strong>\ud83d\udce6 Discreet packaging<\/strong> (plain envelope) &middot; <strong>\ud83c\udf0d Worldwide shipping<\/strong> \u03bc\u03b5 <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u00b7 <strong>\u2b50 1,400+ customers<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<h3 class=\"wp-block-heading\">\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Choosing Tretin Cream from MedsBase:<\/p>\n<ul>\n<li><strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong> \u2014 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c1\u03c5\u03b8\u03bc\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b5\u03b3\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7, \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u03bc\u03b5 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03c0\u03b1\u03c1\u03c4\u03af\u03b4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b7\u03bc\u03b5\u03c1\u03bf\u03bc\u03b7\u03bd\u03af\u03b1 \u03bb\u03ae\u03be\u03b7\u03c2.<\/li>\n<li><strong>\u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/strong> \u2014 \u03b1\u03c0\u03bb\u03cc \u03c6\u03ac\u03ba\u03b5\u03bb\u03bf, \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc.<\/li>\n<li><strong>\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/strong> \u03bc\u03b5 <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u2014 if your parcel does not arrive within 20 business days we re-ship at no cost (subject to policy terms).<\/li>\n<li><strong>\u03a0\u03cc\u03bd\u03c4\u03bf\u03b9 \u03b1\u03c6\u03bf\u03c3\u03af\u03c9\u03c3\u03b7\u03c2<\/strong> \u2014 1 point per $1 spent (excludes peptides); 100 points = $5 off.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">What Tretin Cream is and how it works<\/h2>\n<p>Tretin Cream contains <strong>tretinoin 0.025% or 0.05%<\/strong>. Tretinoin (all-trans retinoic acid) binds nuclear retinoic acid receptors (RAR-\u03b1\/\u03b2\/\u03b3) in keratinocytes, regulating transcription of genes that control cell turnover, sebum production, and dermal collagen synthesis. The result: faster shedding of comedone-forming corneocytes, reduced sebum, normalised follicular keratinisation, and over months, increased dermal collagen and improved photoageing. Manufacturer: Pulse Pharma (WHO-GMP certified).<\/p>\n<h2 class=\"wp-block-heading\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Mild-to-moderate acne vulgaris<\/strong> \u2014 first-line topical for comedonal and inflammatory acne.<\/li>\n<li><strong>Photoageing<\/strong> \u2014 fine lines, uneven pigmentation, roughness, dullness from cumulative UV exposure.<\/li>\n<li><strong>Post-inflammatory hyperpigmentation (PIH)<\/strong> \u2014 dark spots after acne or trauma.<\/li>\n<li><strong>Melasma<\/strong> \u2014 adjunct in Kligman triple combinations.<\/li>\n<li><strong>Keratosis pilaris<\/strong> \u2014 off-label for stubborn cases.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u03a0\u03ce\u03c2 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03b5\u03c4\u03b5 \u03b1\u03af\u03c4\u03b7\u03c3\u03b7<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;\">\u0392\u03ae\u03bc\u03b1<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">\u039b\u03b5\u03c0\u03c4\u03bf\u03bc\u03ad\u03c1\u03b5\u03b9\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Cleanse<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Wash with a gentle non-foaming cleanser. Pat dry. Wait 10\u201315 minutes \u2014 applying tretinoin to damp skin amplifies irritation.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Amount<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Pea-sized for the whole face. More is not better \u2014 excess increases irritation without faster results.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Acclimation<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Start 2\u20133 nights per week for 2 weeks, then alternate nights for 2 weeks, then nightly. Buffer with moisturiser if needed (sandwich method).<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Avoid areas<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Eyelids, corners of mouth and nose, lips. Apply at least 5 mm away.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Sun protection<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Mandatory SPF 30+ broad-spectrum every morning. Tretinoin thins the stratum corneum and increases UV sensitivity.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a7\u03c1\u03bf\u03bd\u03bf\u03b4\u03b9\u03ac\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Acne: visible improvement 8\u201312 weeks. Photoageing: 6\u201312 months. Continued daily use is required for benefit to persist.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:16px 20px;margin:22px 0;border-radius:6px;\">\n<p style=\"margin:0;\"><strong>\u2713 The retinoid purge<\/strong> \u2014 During weeks 2\u20134, acne can transiently worsen as comedones surface and inflame. This &#8220;purge&#8221; is normal and reflects the drug working \u2014 micro-comedones that would have appeared over months are accelerated to the surface. Push through unless lesions are severe or painful. Add a non-comedogenic moisturiser to manage irritation; do not stop unless your dermatologist advises.<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>Very common (initial weeks):<\/strong> dryness, redness, peeling, mild burning. Usually subside by weeks 4\u20136 as skin acclimates.<\/li>\n<li><strong>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> sun sensitivity, transient acne worsening (purge), perioral dermatitis if applied too close to mouth.<\/li>\n<li><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> contact allergy to tretinoin or vehicle, post-inflammatory hyperpigmentation in dark skin.<\/li>\n<li><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1:<\/strong> photoallergic reactions.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<p>Avoid concurrent benzoyl peroxide on the same skin (can oxidise tretinoin \u2014 apply at separate times of day, or use a stable BPO + retinoid formulation). Avoid alpha hydroxy acids, glycolic peels, salicylic acid, and microdermabrasion in the same evening. Pause tretinoin 7 days before any chemical peel or laser. Concurrent vitamin A supplements at high dose increase systemic retinoid load.<\/p>\n<h2 class=\"wp-block-heading\">\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Pregnancy (Category X)<\/strong> \u2014 tretinoin is teratogenic; effective contraception is required.<\/li>\n<li>Breastfeeding (limited data; avoid).<\/li>\n<li>Eczema, severe sunburn, broken skin at the application site.<\/li>\n<li>Known sensitivity to retinoids or vehicle.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>Store below 25 \u00b0C, away from direct light. Tretinoin oxidises in light and air \u2014 keep tube cap firmly closed and out of direct sunlight.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">How long before I see results with Tretin Cream?<\/h3>\n<p>Acne improvement at 8\u201312 weeks; photoageing benefits at 6\u201312 months. Continued nightly use is needed to maintain results.<\/p>\n<h3 class=\"wp-block-heading\">My skin is peeling after 1 week \u2014 is this normal?<\/h3>\n<p>Yes. Peeling, mild redness, and dryness are universal in the first 4\u20136 weeks. Buffer with a non-comedogenic moisturiser, reduce frequency to alternate nights, and use a gentle cleanser. If pain, severe burning, or open skin appear \u2014 stop and consult.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Tretin Cream in pregnancy?<\/h3>\n<p>No. Topical tretinoin is FDA Category X \u2014 teratogenic risk. Stop before conception and use effective contraception throughout treatment.<\/p>\n<h3 class=\"wp-block-heading\">Should I use moisturiser with tretinoin?<\/h3>\n<p>Yes. A non-comedogenic moisturiser before or after tretinoin reduces irritation without significantly reducing efficacy. The &#8220;sandwich method&#8221; \u2014 moisturiser, tretinoin, moisturiser \u2014 is well-established for sensitive skin.<\/p>\n<h3 class=\"wp-block-heading\">Why does my acne look worse after 2 weeks?<\/h3>\n<p>That is the retinoid purge. Comedones that would have surfaced over months are accelerated and inflame. Continue treatment unless severe; the purge resolves by week 4\u20136.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Tretin Cream with benzoyl peroxide?<\/h3>\n<p>Yes, but apply at separate times \u2014 BPO in the morning, tretinoin at night \u2014 unless you have a stable combination product. BPO can oxidise tretinoin in the same application.<\/p>\n<h3 class=\"wp-block-heading\">How is tretinoin different from retinol?<\/h3>\n<p>Retinol is a precursor that the skin must convert to tretinoin (retinoic acid) \u2014 a process that loses ~90% of activity. Tretinoin is the active form, so it is much faster but more irritating. Retinol is gentler but slower (typically 1 strength of retinol \u2248 1\/10 the strength of tretinoin).<\/p>\n<h3 class=\"wp-block-heading\">Can I use Tretin Cream for wrinkles?<\/h3>\n<p>Yes \u2014 long-term nightly use over 6\u201312 months produces measurable improvement in fine lines, uneven pigmentation, and skin texture from UV damage. Tretinoin is the gold-standard topical for photoageing.<\/p>\n<h3 class=\"wp-block-heading\">What happens if I miss a few nights?<\/h3>\n<p>No major issue \u2014 resume your usual schedule. Do not double up to &#8220;catch up&#8221; \u2014 that just increases irritation.<\/p>\n<h3 class=\"wp-block-heading\">Is tretinoin the same as isotretinoin (Accutane)?<\/h3>\n<p>No. Tretinoin (Tretin Cream) is topical and has minimal systemic absorption. Isotretinoin is the oral retinoid for severe acne and has very different (and stronger) systemic effects. Both are teratogenic.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Other Beauty &amp; Skin Care Medications<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/melalite-forte-cream\/\"><strong>Melalite Forte Cream \u2014 hydroquinone 4% for melasma<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/retino-a-cream\/\"><strong>Retino-A Cream \u2014 tretinoin for acne and ageing<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/melacare-cream\/\"><strong>Melacare Cream \u2014 Kligman triple for melasma<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/permite-cream\/\"><strong>Permite Cream \u2014 permethrin 5% for scabies<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tenovate-cream\/\"><strong>Tenovate Cream \u2014 clobetasol 0.05% for severe inflammation<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:6px;font-size:0.95em;\">\n<p style=\"margin:0;\"><strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd.<\/strong> This content is for general information about the product and is not medical advice or a substitute for advice from a qualified healthcare professional. Use any topical or oral medication only under appropriate medical supervision; misuse can cause serious harm.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Reduces Acne Breakouts<br \/>\n\u2705 Promotes Skin Renewal<br \/>\n\u2705 Lightens Skin Discoloration<br \/>\n\u2705 Minimizes Fine Lines<br \/>\n\u2705 Improves Skin Texture<\/p>","protected":false},"featured_media":54147,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3642,3141,3342],"product_tag":[],"class_list":{"0":"post-54146","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-beauty-skin-care","7":"product_cat-category-overview","8":"product_cat-general-health","10":"first","11":"outofstock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/54146","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=54146"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/54147"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=54146"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=54146"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=54146"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=54146"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}