{"id":54191,"date":"2023-09-20T09:55:39","date_gmt":"2023-09-20T09:55:39","guid":{"rendered":"https:\/\/medsname.com\/supatret-gel\/"},"modified":"2026-04-30T10:25:01","modified_gmt":"2026-04-30T10:25:01","slug":"supatret-gel","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/supatret-gel\/","title":{"rendered":"Supatret Gel"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:20px 0;border-radius:6px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:1.15em;\">\ud83d\udca1 Quick Answer \u2014 What is Supatret 0.04 Aqueous Gel?<\/h3>\n<p style=\"margin:0;\"><strong>Supatret 0.04 Aqueous Gel<\/strong> contains tretinoin 0.04% (microsphere aqueous gel) \u2014 a topical retinoid (vitamin A derivative) for mild-to-moderate acne vulgaris, photoageing (fine lines, uneven tone), and post-inflammatory hyperpigmentation. Apply a pea-sized amount at bedtime to clean dry skin. Start 2\u20133 nights per week for the first 2 weeks; increase frequency as the skin acclimates. Use SPF 30+ daily. Visible improvement takes 8\u201312 weeks. Initial flare (&#8220;retinoid purge&#8221;) at weeks 2\u20134 is normal \u2014 do not stop unless severe.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:6px;font-size:0.95em;\">\n<strong>\ud83c\udfed WHO-GMP certified manufacturer<\/strong> \u00b7 <strong>\ud83d\udce6 Discreet packaging<\/strong> (plain envelope) &middot; <strong>\ud83c\udf0d Worldwide shipping<\/strong> \u03bc\u03b5 <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u00b7 <strong>\u2b50 1,400+ customers<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<h3 class=\"wp-block-heading\">\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Choosing Supatret 0.04 Aqueous Gel from MedsBase:<\/p>\n<ul>\n<li><strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong> \u2014 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c1\u03c5\u03b8\u03bc\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b5\u03b3\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7, \u03bf\u03bb\u03bf\u03ba\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u03bc\u03b5 \u03b1\u03c1\u03b9\u03b8\u03bc\u03cc \u03c0\u03b1\u03c1\u03c4\u03af\u03b4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b7\u03bc\u03b5\u03c1\u03bf\u03bc\u03b7\u03bd\u03af\u03b1 \u03bb\u03ae\u03be\u03b7\u03c2.<\/li>\n<li><strong>\u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/strong> \u2014 \u03b1\u03c0\u03bb\u03cc \u03c6\u03ac\u03ba\u03b5\u03bb\u03bf, \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc.<\/li>\n<li><strong>\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/strong> \u03bc\u03b5 <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u2014 if your parcel does not arrive within 20 business days we re-ship at no cost (subject to policy terms).<\/li>\n<li><strong>\u03a0\u03cc\u03bd\u03c4\u03bf\u03b9 \u03b1\u03c6\u03bf\u03c3\u03af\u03c9\u03c3\u03b7\u03c2<\/strong> \u2014 1 point per $1 spent (excludes peptides); 100 points = $5 off.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">What Supatret 0.04 Aqueous Gel is and how it works<\/h2>\n<p>Supatret 0.04 Aqueous Gel contains <strong>tretinoin 0.04% (microsphere aqueous gel)<\/strong>. Tretinoin (all-trans retinoic acid) binds nuclear retinoic acid receptors (RAR-\u03b1\/\u03b2\/\u03b3) in keratinocytes, regulating transcription of genes that control cell turnover, sebum production, and dermal collagen synthesis. The result: faster shedding of comedone-forming corneocytes, reduced sebum, normalised follicular keratinisation, and over months, increased dermal collagen and improved photoageing. This formulation uses microsphere technology \u2014 tretinoin is encapsulated in porous polymer microspheres that release the drug slowly, reducing irritation while preserving efficacy. Manufacturer: Sun Pharma (WHO-GMP certified).<\/p>\n<h2 class=\"wp-block-heading\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Mild-to-moderate acne vulgaris<\/strong> \u2014 first-line topical for comedonal and inflammatory acne.<\/li>\n<li><strong>Photoageing<\/strong> \u2014 fine lines, uneven pigmentation, roughness, dullness from cumulative UV exposure.<\/li>\n<li><strong>Post-inflammatory hyperpigmentation (PIH)<\/strong> \u2014 dark spots after acne or trauma.<\/li>\n<li><strong>Melasma<\/strong> \u2014 adjunct in Kligman triple combinations.<\/li>\n<li><strong>Keratosis pilaris<\/strong> \u2014 off-label for stubborn cases.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u03a0\u03ce\u03c2 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03b5\u03c4\u03b5 \u03b1\u03af\u03c4\u03b7\u03c3\u03b7<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;\">\u0392\u03ae\u03bc\u03b1<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">\u039b\u03b5\u03c0\u03c4\u03bf\u03bc\u03ad\u03c1\u03b5\u03b9\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Cleanse<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Wash with a gentle non-foaming cleanser. Pat dry. Wait 10\u201315 minutes \u2014 applying tretinoin to damp skin amplifies irritation.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Amount<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Pea-sized for the whole face. More is not better \u2014 excess increases irritation without faster results.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Acclimation<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Start 2\u20133 nights per week for 2 weeks, then alternate nights for 2 weeks, then nightly. Buffer with moisturiser if needed (sandwich method).<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Avoid areas<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Eyelids, corners of mouth and nose, lips. Apply at least 5 mm away.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Sun protection<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Mandatory SPF 30+ broad-spectrum every morning. Tretinoin thins the stratum corneum and increases UV sensitivity.<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a7\u03c1\u03bf\u03bd\u03bf\u03b4\u03b9\u03ac\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Acne: visible improvement 8\u201312 weeks. Photoageing: 6\u201312 months. Continued daily use is required for benefit to persist.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:16px 20px;margin:22px 0;border-radius:6px;\">\n<p style=\"margin:0;\"><strong>\u2713 The retinoid purge<\/strong> \u2014 During weeks 2\u20134, acne can transiently worsen as comedones surface and inflame. This &#8220;purge&#8221; is normal and reflects the drug working \u2014 micro-comedones that would have appeared over months are accelerated to the surface. Push through unless lesions are severe or painful. Add a non-comedogenic moisturiser to manage irritation; do not stop unless your dermatologist advises.<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>Very common (initial weeks):<\/strong> dryness, redness, peeling, mild burning. Usually subside by weeks 4\u20136 as skin acclimates.<\/li>\n<li><strong>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> sun sensitivity, transient acne worsening (purge), perioral dermatitis if applied too close to mouth.<\/li>\n<li><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> contact allergy to tretinoin or vehicle, post-inflammatory hyperpigmentation in dark skin.<\/li>\n<li><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1:<\/strong> photoallergic reactions.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<p>Avoid concurrent benzoyl peroxide on the same skin (can oxidise tretinoin \u2014 apply at separate times of day, or use a stable BPO + retinoid formulation). Avoid alpha hydroxy acids, glycolic peels, salicylic acid, and microdermabrasion in the same evening. Pause tretinoin 7 days before any chemical peel or laser. Concurrent vitamin A supplements at high dose increase systemic retinoid load.<\/p>\n<h2 class=\"wp-block-heading\">\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Pregnancy (Category X)<\/strong> \u2014 tretinoin is teratogenic; effective contraception is required.<\/li>\n<li>Breastfeeding (limited data; avoid).<\/li>\n<li>Eczema, severe sunburn, broken skin at the application site.<\/li>\n<li>Known sensitivity to retinoids or vehicle.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>Store below 25 \u00b0C, away from direct light. Tretinoin oxidises in light and air \u2014 keep tube cap firmly closed and out of direct sunlight.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">How long before I see results with Supatret 0.04 Aqueous Gel?<\/h3>\n<p>Acne improvement at 8\u201312 weeks; photoageing benefits at 6\u201312 months. Continued nightly use is needed to maintain results.<\/p>\n<h3 class=\"wp-block-heading\">My skin is peeling after 1 week \u2014 is this normal?<\/h3>\n<p>Yes. Peeling, mild redness, and dryness are universal in the first 4\u20136 weeks. Buffer with a non-comedogenic moisturiser, reduce frequency to alternate nights, and use a gentle cleanser. If pain, severe burning, or open skin appear \u2014 stop and consult.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Supatret 0.04 Aqueous Gel in pregnancy?<\/h3>\n<p>No. Topical tretinoin is FDA Category X \u2014 teratogenic risk. Stop before conception and use effective contraception throughout treatment.<\/p>\n<h3 class=\"wp-block-heading\">Should I use moisturiser with tretinoin?<\/h3>\n<p>Yes. A non-comedogenic moisturiser before or after tretinoin reduces irritation without significantly reducing efficacy. The &#8220;sandwich method&#8221; \u2014 moisturiser, tretinoin, moisturiser \u2014 is well-established for sensitive skin.<\/p>\n<h3 class=\"wp-block-heading\">Why does my acne look worse after 2 weeks?<\/h3>\n<p>That is the retinoid purge. Comedones that would have surfaced over months are accelerated and inflame. Continue treatment unless severe; the purge resolves by week 4\u20136.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Supatret 0.04 Aqueous Gel with benzoyl peroxide?<\/h3>\n<p>Yes, but apply at separate times \u2014 BPO in the morning, tretinoin at night \u2014 unless you have a stable combination product. BPO can oxidise tretinoin in the same application.<\/p>\n<h3 class=\"wp-block-heading\">How is tretinoin different from retinol?<\/h3>\n<p>Retinol is a precursor that the skin must convert to tretinoin (retinoic acid) \u2014 a process that loses ~90% of activity. Tretinoin is the active form, so it is much faster but more irritating. Retinol is gentler but slower (typically 1 strength of retinol \u2248 1\/10 the strength of tretinoin).<\/p>\n<h3 class=\"wp-block-heading\">Can I use Supatret 0.04 Aqueous Gel for wrinkles?<\/h3>\n<p>Yes \u2014 long-term nightly use over 6\u201312 months produces measurable improvement in fine lines, uneven pigmentation, and skin texture from UV damage. Tretinoin is the gold-standard topical for photoageing.<\/p>\n<h3 class=\"wp-block-heading\">What happens if I miss a few nights?<\/h3>\n<p>No major issue \u2014 resume your usual schedule. Do not double up to &#8220;catch up&#8221; \u2014 that just increases irritation.<\/p>\n<h3 class=\"wp-block-heading\">Is tretinoin the same as isotretinoin (Accutane)?<\/h3>\n<p>No. Tretinoin (Supatret 0.04 Aqueous Gel) is topical and has minimal systemic absorption. Isotretinoin is the oral retinoid for severe acne and has very different (and stronger) systemic effects. Both are teratogenic.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Other Beauty &amp; Skin Care Medications<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/melalite-forte-cream\/\"><strong>Melalite Forte Cream \u2014 hydroquinone 4% for melasma<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/retino-a-cream\/\"><strong>Retino-A Cream \u2014 tretinoin for acne and ageing<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/melacare-cream\/\"><strong>Melacare Cream \u2014 Kligman triple for melasma<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/permite-cream\/\"><strong>Permite Cream \u2014 permethrin 5% for scabies<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tenovate-cream\/\"><strong>Tenovate Cream \u2014 clobetasol 0.05% for severe inflammation<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:6px;font-size:0.95em;\">\n<p style=\"margin:0;\"><strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd.<\/strong> This content is for general information about the product and is not medical advice or a substitute for advice from a qualified healthcare professional. Use any topical or oral medication only under appropriate medical supervision; misuse can cause serious harm.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Acne treatment solution<br \/>\n\u2705 Promotes skin renewal<br \/>\n\u2705 \u039c\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03c4\u03bf\u03c5 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2<br \/>\n\u2705 Minimizes pore blockage<br \/>\n\u2705 Improves skin texture<\/p>","protected":false},"featured_media":54192,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3642,3141,3342],"product_tag":[],"class_list":{"0":"post-54191","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-beauty-skin-care","7":"product_cat-category-overview","8":"product_cat-general-health","10":"first","11":"outofstock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/54191","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=54191"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/54192"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=54191"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=54191"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=54191"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=54191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}