{"id":54314,"date":"2023-09-20T09:57:36","date_gmt":"2023-09-20T09:57:36","guid":{"rendered":"https:\/\/medsname.com\/duolin-inhaler\/"},"modified":"2026-04-30T10:24:59","modified_gmt":"2026-04-30T10:24:59","slug":"duolin-inhaler","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/duolin-inhaler\/","title":{"rendered":"Duolin Inhaler"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Duolin Inhaler?<\/h3>\n<p><strong>Duolin Inhaler<\/strong> \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 <strong>ipratropium bromide + levosalbutamol<\/strong>, used as a <strong>reliever for acute bronchospasm<\/strong> in <strong>asthma<\/strong> \u03ba\u03b1\u03b9 <strong>COPD<\/strong>. The combination delivers two complementary bronchodilators in one dose: <strong>levosalbutamol<\/strong> (a short-acting \u03b22 agonist with rapid 1\u20135 min onset) and <strong>ipratropium<\/strong> (a short-acting muscarinic antagonist with onset by 15 min). Combined, they provide more complete bronchodilation than either alone \u2014 particularly in COPD where parasympathetic tone is the dominant reversible component. Manufactured by <strong>Cipla<\/strong>. Each inhaler delivers <strong>ipratropium 20 mcg + levosalbutamol 50 mcg per actuation<\/strong>.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Encrypted Checkout<\/strong> \u00b7 <strong>\ud83d\udcb3 Verified Processor<\/strong> \u00b7 <strong>\ud83d\ude9a Worldwide Shipping<\/strong> \u00b7 <strong>\u2b50 4.9\/5 from 1,400+ customers<\/strong>\n<\/div>\n<h2>What Is Duolin Inhaler?<\/h2>\n<p>Duolin Inhaler is a fixed-dose combination of ipratropium and levosalbutamol manufactured by Cipla at WHO-GMP certified facilities. Internationally the same combination is sold as Combivent (DuoNeb).<\/p>\n<h2>How Does Duolin Inhaler Work?<\/h2>\n<ul>\n<li><strong>Ipratropium<\/strong> blocks M1, M2, and M3 muscarinic receptors on airway smooth muscle, neutralising parasympathetic tone \u2014 onset 15 min, duration 4\u20136 hours.<\/li>\n<li><strong>\u039b\u03b5\u03b2\u03bf\u03c3\u03b1\u03bb\u03b2\u03bf\u03c5\u03c4\u03b1\u03bc\u03cc\u03bb\u03b7<\/strong> (active R-isomer of salbutamol) activates \u03b22 receptors, raising cyclic AMP and producing rapid bronchodilation \u2014 onset 1\u20135 min, duration 4\u20136 hours.<\/li>\n<li><strong>Synergy:<\/strong> the two pathways act in parallel, giving deeper bronchodilation than either alone \u2014 particularly useful in COPD and acute severe asthma.<\/li>\n<\/ul>\n<h2>\u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Acute COPD exacerbations<\/strong> \u2014 first-line bronchodilator alongside or instead of a SABA<\/li>\n<li><strong>Acute severe asthma<\/strong> \u2014 added to high-dose SABA in moderate-to-severe attacks (paediatric and adult)<\/li>\n<li><strong>Chronic COPD symptomatic relief<\/strong> \u2014 when LAMA is unavailable or short-acting cover is preferred<\/li>\n<li><strong>Bronchospasm secondary to viral wheeze, bronchiolitis<\/strong> in young children (case-by-case)<\/li>\n<\/ul>\n<h2>Duolin Inhaler Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Patient<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u0394\u03cc\u03c3\u03b7<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u03a3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Adults \u2014 acute<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>2 puffs<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Every 4\u20136 hours; up to 4\u00d7 daily<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Children &gt;6 yr<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1\u20132 puffs<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Every 4\u20136 hours via spacer<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>How to Use Duolin Inhaler Properly<\/h3>\n<ul>\n<li>Shake well; remove the cap.<\/li>\n<li>Breathe out fully away from the device.<\/li>\n<li>Seal lips around the mouthpiece.<\/li>\n<li>Press at the start of a slow deep breath (3\u20135 seconds).<\/li>\n<li>Hold breath 10 seconds, then breathe out gently.<\/li>\n<li>Wait 30 seconds before second puff.<\/li>\n<li>Use a spacer for children, the elderly, and during acute attacks.<\/li>\n<\/ul>\n<h2>Side Effects of Duolin Inhaler<\/h2>\n<ul>\n<li>Dry mouth (anticholinergic)<\/li>\n<li>Throat irritation, cough<\/li>\n<li>Mild headache<\/li>\n<li>Mild tremor and palpitations (\u03b22 effects from levosalbutamol)<\/li>\n<li>Bitter or metallic taste<\/li>\n<li>Eye irritation if mist contacts eyes<\/li>\n<\/ul>\n<p><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2:<\/strong><\/p>\n<ul>\n<li>Acute angle-closure glaucoma (avoid mist near eyes; use mouthpiece preferred over mask)<\/li>\n<li>Acute urinary retention in patients with prostatic obstruction<\/li>\n<li>\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b1\u03bb\u03bb\u03b5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/li>\n<li>Paradoxical bronchospasm<\/li>\n<\/ul>\n<h2>\u03a0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03ac\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Avoid mist near eyes<\/strong> \u2014 risk of acute glaucoma in predisposed patients (narrow anterior chamber, family history). Use mouthpiece rather than mask where possible.<\/li>\n<li><strong>Prostatic obstruction:<\/strong> caution in older men; risk of urinary retention.<\/li>\n<li><strong>Cardiovascular disease:<\/strong> caution with arrhythmias and severe coronary disease (\u03b22 component)<\/li>\n<li><strong>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7:<\/strong> low-risk; uncontrolled asthma is more dangerous than the medication.<\/li>\n<li><strong>Carry a SABA reliever for asthma rescue<\/strong> \u2014 ipratropium has slower onset.<\/li>\n<\/ul>\n<h2>\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li>Hypersensitivity to ipratropium, atropine derivatives, levosalbutamol, or excipients<\/li>\n<li>Severe lactose \/ milk-protein hypersensitivity (DPI)<\/li>\n<\/ul>\n<h2>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Interacting drug<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u0391\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u03a4\u03b9 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03b5\u03c4\u03b5<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Non-selective beta-blockers (propranolol, timolol drops)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Block \u03b22 effect \u2014 can precipitate severe bronchospasm<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Avoid; switch to cardioselective beta-blocker if essential<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Loop or thiazide diuretics<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive hypokalaemia<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor serum potassium with high doses<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Systemic corticosteroids<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive hypokalaemia + hyperglycaemia<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor electrolytes and glucose<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Theophylline \/ aminophylline<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Additive tachycardia and hypokalaemia<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor heart rate and potassium<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">MAOIs and tricyclic antidepressants<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Potentiate cardiovascular effects<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Caution \u2014 monitor BP\/HR<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">\u039d\u03c4\u03b9\u03b3\u03ba\u03bf\u03be\u03af\u03bd\u03b7<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Hypokalaemia increases digoxin toxicity risk<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor potassium; check digoxin level if symptomatic<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<ul>\n<li>Store below <strong>25\u00b0C<\/strong>, protected from direct sunlight and heat.<\/li>\n<li>Do not refrigerate. Do not freeze.<\/li>\n<li>Do not puncture the canister; even an empty canister can explode if heated.<\/li>\n<li>Keep out of reach of children. Use within the expiry date printed on the canister.<\/li>\n<\/ul>\n<h2>\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u039b\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/asthalin-inhaler\/\"><strong>Asthalin Inhaler \u2014 salbutamol reliever<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/budecort-inhaler\/\"><strong>Budecort Inhaler \u2014 budesonide ICS preventer<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/foracort-inhaler\/\"><strong>Foracort Inhaler \u2014 budesonide + formoterol ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tiova-inhaler\/\"><strong>Tiova Inhaler \u2014 tiotropium LAMA for COPD<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/montair\/\"><strong>Montair \u2014 montelukast LTRA tablet<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>Is Duolin the same as Combivent?<\/h3>\n<p>Combivent (Boehringer Ingelheim) contains ipratropium + albuterol (salbutamol). Duolin (Cipla) contains ipratropium + levosalbutamol \u2014 the active R-isomer. Clinically equivalent at half the levosalbutamol milligram dose, with potentially less tremor.<\/p>\n<h3>When is a SAMA + SABA combination used?<\/h3>\n<p>Most commonly in acute COPD exacerbations and moderate-to-severe acute asthma. In stable disease, the combination is sometimes used as an as-needed reliever, though modern guidelines favour ICS-formoterol SMART\/MART for asthma.<\/p>\n<h3>How fast does Duolin work?<\/h3>\n<p>Levosalbutamol begins bronchodilation in 1\u20135 minutes; ipratropium adds in 15\u201330 minutes. Total combined duration 4\u20136 hours.<\/p>\n<h3>How often can I use Duolin?<\/h3>\n<p>Up to 4\u00d7 daily routinely; back-to-back every 20 minutes \u00d73 in severe attacks under supervision.<\/p>\n<h3>Can children use Duolin?<\/h3>\n<p>Yes in age-appropriate strength under medical supervision. Often used in paediatric A&#038;E for moderate-severe asthma attacks.<\/p>\n<h3>Is Duolin safe in pregnancy?<\/h3>\n<p>Both molecules have reassuring pregnancy data. Uncontrolled asthma is more dangerous than the combination.<\/p>\n<h3>Why dry mouth on Duolin?<\/h3>\n<p>Anticholinergic effect from ipratropium. Sips of water, gum, oral hygiene help.<\/p>\n<h3>Can I use Duolin Respules with budesonide?<\/h3>\n<p>Yes \u2014 co-nebulising Duolin with Budecort Respules in the same cup is common in moderate-to-severe acute attacks. Empty all respules into the cup; nebulise as one session.<\/p>\n<h3>Is Duolin a maintenance therapy?<\/h3>\n<p>It can be used regularly in COPD as 4\u00d7 daily maintenance, though modern guidelines prefer once-daily LAMA (Tiova, Airz) \u00b1 LABA. For asthma, regular use of SABA-containing relievers is no longer recommended \u2014 switch to ICS-LABA.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medical disclaimer:<\/strong> This page is educational and does not replace professional medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any inhaler or respiratory medication, especially if you have other medical conditions, take other prescriptions, are pregnant or breastfeeding, or are over 65.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 <strong>\u03a7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/pirox-gel\/\">Pirox Gel<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/losatec-h\/\">Losatec H<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/gravitor\/\">Gravitor<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/app-up\/\">App-Up<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/sibelium\/\">Sibelium<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<h5>\u2705 Effective asthma control<br \/>\n\u2705 Quick symptom relief<br \/>\n\u2705 Convenient inhalation method<br \/>\n\u2705 Enhanced respiratory comfort<\/h5>\n<p><span style=\"color: #999999;\">Contains Levosalbutamol and Ipratropium Bromide<\/span><\/p>","protected":false},"featured_media":54315,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[3708,3709,3710],"class_list":{"0":"post-54314","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-duolin-inhaler","10":"product_tag-ipratropium-bromide","11":"product_tag-levosalbutamol","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/54314","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=54314"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/54315"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=54314"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=54314"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=54314"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=54314"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}