{"id":54320,"date":"2023-09-20T09:57:37","date_gmt":"2023-09-20T09:57:37","guid":{"rendered":"https:\/\/medsname.com\/duolin-respules\/"},"modified":"2026-04-30T14:22:10","modified_gmt":"2026-04-30T14:22:10","slug":"duolin-respules","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/duolin-respules\/","title":{"rendered":"Duolin Respules"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Duolin Respules?<\/h3>\n<p><strong>Duolin Respules<\/strong> \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 <strong>ipratropium bromide + levosalbutamol<\/strong>, used as a <strong>reliever for acute bronchospasm<\/strong> in <strong>asthma<\/strong> \u03ba\u03b1\u03b9 <strong>COPD<\/strong>. The combination delivers two complementary bronchodilators in one dose: <strong>\u03bb\u03b5\u03b2\u03bf\u03c3\u03b1\u03bb\u03b2\u03bf\u03c5\u03c4\u03b1\u03bc\u03cc\u03bb\u03b7<\/strong> (a short-acting \u03b22 agonist with rapid 1\u20135 min onset) and <strong>ipratropium<\/strong> (a short-acting muscarinic antagonist with onset by 15 min). Combined, they provide more complete bronchodilation than either alone \u2014 particularly in COPD where parasympathetic tone is the dominant reversible component. Manufactured by <strong>Cipla<\/strong>. Each respules delivers <strong>ipratropium 500 mcg + levosalbutamol 1.25 mg in 2.5 ml<\/strong>.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 \u039a\u03c1\u03c5\u03c0\u03c4\u03bf\u03b3\u03c1\u03b1\u03c6\u03b7\u03bc\u03ad\u03bd\u03b7 \u039f\u03bb\u03bf\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u0391\u03b3\u03bf\u03c1\u03ac\u03c2<\/strong> \u00b7 <strong>\ud83d\udcb3 \u0395\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf\u03c2 \u0395\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c2<\/strong> \u00b7 <strong>\ud83d\ude9a \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u0391\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/strong> \u00b7 <strong>\u2b50 4.9\/5 \u03b1\u03c0\u03cc 1,400+ \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2<\/strong>\n<\/div>\n<h2>What Is Duolin Respules?<\/h2>\n<p>Duolin Respules is a fixed-dose combination of ipratropium and levosalbutamol manufactured by Cipla at WHO-GMP certified facilities. Internationally the same combination is sold as Combivent (DuoNeb).<\/p>\n<h2>How Does Duolin Respules Work?<\/h2>\n<ul>\n<li><strong>Ipratropium<\/strong> blocks M1, M2, and M3 muscarinic receptors on airway smooth muscle, neutralising parasympathetic tone \u2014 onset 15 min, duration 4\u20136 hours.<\/li>\n<li><strong>\u039b\u03b5\u03b2\u03bf\u03c3\u03b1\u03bb\u03b2\u03bf\u03c5\u03c4\u03b1\u03bc\u03cc\u03bb\u03b7<\/strong> (active R-isomer of salbutamol) activates \u03b22 receptors, raising cyclic AMP and producing rapid bronchodilation \u2014 onset 1\u20135 min, duration 4\u20136 hours.<\/li>\n<li><strong>Synergy:<\/strong> the two pathways act in parallel, giving deeper bronchodilation than either alone \u2014 particularly useful in COPD and acute severe asthma.<\/li>\n<\/ul>\n<h2>\u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Acute COPD exacerbations<\/strong> \u2014 first-line bronchodilator alongside or instead of a SABA<\/li>\n<li><strong>Acute severe asthma<\/strong> \u2014 added to high-dose SABA in moderate-to-severe attacks (paediatric and adult)<\/li>\n<li><strong>Chronic COPD symptomatic relief<\/strong> \u2014 when LAMA is unavailable or short-acting cover is preferred<\/li>\n<li><strong>Bronchospasm secondary to viral wheeze, bronchiolitis<\/strong> in young children (case-by-case)<\/li>\n<\/ul>\n<h2>Duolin Respules Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u0391\u03c3\u03b8\u03b5\u03bd\u03ae\u03c2<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u0394\u03cc\u03c3\u03b7<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u03a3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Adults \u2014 acute<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>1 respule<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Every 4\u20136 h; back-to-back \u00d7 3 in severe attacks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03b1\u03b9\u03b4\u03b9\u03ac 6\u201312 \u03b5\u03c4\u03ce\u03bd<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>0.5 respule (half)<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Every 4\u20136 hours<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>How to Use Duolin Respules Properly<\/h3>\n<ul>\n<li>Wash hands; assemble a clean dry nebuliser, cup, and mask or mouthpiece.<\/li>\n<li>Twist off the respule top; squeeze contents into the cup.<\/li>\n<li>Switch on the compressor \u2014 fine mist appears within seconds.<\/li>\n<li>Breathe normally with occasional deep breaths; ensure tight mask seal in children.<\/li>\n<li>Continue 5\u201310 minutes until the cup sputters.<\/li>\n<li>Discard any unused respule; rinse cup and mouthpiece, air-dry.<\/li>\n<li><strong>Avoid mist near the eyes<\/strong> \u2014 risk of glaucoma.<\/li>\n<\/ul>\n<h2>Side Effects of Duolin Respules<\/h2>\n<ul>\n<li>Dry mouth (anticholinergic)<\/li>\n<li>Throat irritation, cough<\/li>\n<li>Mild headache<\/li>\n<li>Mild tremor and palpitations (\u03b22 effects from levosalbutamol)<\/li>\n<li>Bitter or metallic taste<\/li>\n<li>Eye irritation if mist contacts eyes<\/li>\n<\/ul>\n<p><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2:<\/strong><\/p>\n<ul>\n<li>Acute angle-closure glaucoma (avoid mist near eyes; use mouthpiece preferred over mask)<\/li>\n<li>Acute urinary retention in patients with prostatic obstruction<\/li>\n<li>\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b1\u03bb\u03bb\u03b5\u03c1\u03b3\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/li>\n<li>\u03a0\u03b1\u03c1\u03b1\u03b4\u03bf\u03be\u03b9\u03ba\u03cc\u03c2 \u03b2\u03c1\u03bf\u03b3\u03c7\u03cc\u03c3\u03c0\u03b1\u03c3\u03bc\u03bf\u03c2<\/li>\n<\/ul>\n<h2>\u03a0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03ac\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Avoid mist near eyes<\/strong> \u2014 risk of acute glaucoma in predisposed patients (narrow anterior chamber, family history). Use mouthpiece rather than mask where possible.<\/li>\n<li><strong>Prostatic obstruction:<\/strong> caution in older men; risk of urinary retention.<\/li>\n<li><strong>\u039a\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03bd\u03cc\u03c3\u03bf\u03c2:<\/strong> caution with arrhythmias and severe coronary disease (\u03b22 component)<\/li>\n<li><strong>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7:<\/strong> low-risk; uncontrolled asthma is more dangerous than the medication.<\/li>\n<li><strong>Carry a SABA reliever for asthma rescue<\/strong> \u2014 ipratropium has slower onset.<\/li>\n<\/ul>\n<h2>\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li>Hypersensitivity to ipratropium, atropine derivatives, levosalbutamol, or excipients<\/li>\n<li>Severe lactose \/ milk-protein hypersensitivity (DPI)<\/li>\n<\/ul>\n<h2>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7\u03c2<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u0391\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u03a4\u03b9 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03b5\u03c4\u03b5<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u039c\u03b7 \u03b5\u03ba\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03ac \u03b2-\u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 (\u03c0\u03c1\u03bf\u03c0\u03c1\u03b1\u03bd\u03cc\u03bb\u03bf\u03bb\u03b7, \u03c3\u03c4\u03b1\u03b3\u03cc\u03bd\u03b5\u03c2 \u03c4\u03b9\u03bc\u03bf\u03bb\u03cc\u03bb\u03b7\u03c2)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0391\u03c0\u03bf\u03ba\u03bb\u03b5\u03af\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b22 \u2014 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc \u03b2\u03c1\u03bf\u03b3\u03c7\u03cc\u03c3\u03c0\u03b1\u03c3\u03bc\u03bf<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0391\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5\u00b7 \u03b5\u03ac\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf, \u03b1\u03bb\u03bb\u03ac\u03be\u03c4\u03b5 \u03c3\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03b5\u03ba\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc \u03b2-\u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0394\u03b9\u03bf\u03c5\u03c1\u03b7\u03c4\u03b9\u03ba\u03ac \u03b2\u03c1\u03cc\u03b3\u03c7\u03bf\u03c5 \u03ae \u03b8\u03b5\u03b9\u03b1\u03b6\u03af\u03b4\u03b7\u03c2<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03c1\u03bf\u03c3\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03ba\u03b1\u03bb\u03b9\u03b1\u03b9\u03bc\u03af\u03b1<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03c3\u03c4\u03b5 \u03c4\u03bf \u03bf\u03c1\u03b9\u03ba\u03cc \u03ba\u03ac\u03bb\u03b9\u03bf \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ad\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b9\u03ba\u03ac \u03ba\u03bf\u03c1\u03c4\u03b9\u03ba\u03bf\u03c3\u03c4\u03b5\u03c1\u03bf\u03b5\u03b9\u03b4\u03ae<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03c1\u03bf\u03c3\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03bf\u03ba\u03b1\u03bb\u03b9\u03b1\u03b9\u03bc\u03af\u03b1 + \u03c5\u03c0\u03b5\u03c1\u03b3\u03bb\u03c5\u03ba\u03b1\u03b9\u03bc\u03af\u03b1<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bb\u03c5\u03c4\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7\u03c2<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0398\u03b5\u03bf\u03c6\u03c5\u03bb\u03bb\u03af\u03bd\u03b7 \/ \u03b1\u03bc\u03b9\u03bd\u03bf\u03c6\u03c5\u03bb\u03bb\u03af\u03bd\u03b7<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03c1\u03bf\u03c3\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c4\u03b1\u03c7\u03c5\u03ba\u03b1\u03c1\u03b4\u03af\u03b1 \u03ba\u03b1\u03b9 \u03c5\u03c0\u03bf\u03ba\u03b1\u03bb\u03b9\u03b1\u03b9\u03bc\u03af\u03b1<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03bb\u03af\u03bf\u03c5<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">MAOI \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b9\u03ba\u03c5\u03ba\u03bb\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c4\u03b1\u03b8\u03bb\u03b9\u03c0\u03c4\u03b9\u03ba\u03ac<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0395\u03bd\u03b9\u03c3\u03c7\u03cd\u03bf\u03c5\u03bd \u03c4\u03b9\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03c1\u03bf\u03c3\u03bf\u03c7\u03ae \u2014 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03c0\u03af\u03b5\u03c3\u03b7\u03c2\/\u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">\u039d\u03c4\u03b9\u03b3\u03ba\u03bf\u03be\u03af\u03bd\u03b7<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0397 \u03c5\u03c0\u03bf\u03ba\u03b1\u03bb\u03b9\u03b1\u03b9\u03bc\u03af\u03b1 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03c4\u03bf\u03be\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03b9\u03b3\u03bf\u03be\u03af\u03bd\u03b7\u03c2<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7 \u03ba\u03b1\u03bb\u03af\u03bf\u03c5\u00b7 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03c2 \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03bf\u03c5 \u03b4\u03b9\u03b3\u03bf\u03be\u03af\u03bd\u03b7\u03c2 \u03b5\u03ac\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<ul>\n<li>\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7 \u03ba\u03ac\u03c4\u03c9 \u03b1\u03c0\u03cc <strong>25\u00b0C<\/strong>, protected from direct light.<\/li>\n<li>Keep respules in their original foil overwrap until immediately before use.<\/li>\n<li>Once a respule is opened, use immediately; discard any remainder.<\/li>\n<li>Do not refrigerate. Keep out of reach of children.<\/li>\n<\/ul>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u039b\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/asthalin-inhaler\/\"><strong>Asthalin Inhaler \u2014 \u03c3\u03b1\u03bb\u03b2\u03bf\u03c5\u03c4\u03b1\u03bc\u03cc\u03bb\u03b7 \u03b3\u03b9\u03b1 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b1\u03bd\u03b1\u03ba\u03bf\u03cd\u03c6\u03b9\u03c3\u03b7<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/budecort-inhaler\/\"><strong>Budecort Inhaler \u2014 \u03b2\u03bf\u03c5\u03b4\u03b5\u03c3\u03bf\u03bd\u03bf\u03af\u03b4\u03b7 ICS \u03b3\u03b9\u03b1 \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/foracort-inhaler\/\"><strong>Foracort Inhaler \u2014 \u03b2\u03bf\u03c5\u03b4\u03b5\u03c3\u03bf\u03bd\u03bf\u03af\u03b4\u03b7 + \u03c6\u03bf\u03c1\u03bc\u03bf\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7 ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tiova-inhaler\/\"><strong>Tiova Inhaler \u2014 \u03c4\u03b9\u03bf\u03c4\u03c1\u03bf\u03c0\u03af\u03bf\u03c5 LAMA \u03b3\u03b9\u03b1 \u03a7\u0391\u03a0<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/montair\/\"><strong>Montair \u2014 \u03c4\u03b1\u03bc\u03c0\u03bb\u03ad\u03c4\u03b1 montelukast LTRA<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>Is Duolin the same as Combivent?<\/h3>\n<p>Combivent (Boehringer Ingelheim) contains ipratropium + albuterol (salbutamol). Duolin (Cipla) contains ipratropium + levosalbutamol \u2014 the active R-isomer. Clinically equivalent at half the levosalbutamol milligram dose, with potentially less tremor.<\/p>\n<h3>When is a SAMA + SABA combination used?<\/h3>\n<p>Most commonly in acute COPD exacerbations and moderate-to-severe acute asthma. In stable disease, the combination is sometimes used as an as-needed reliever, though modern guidelines favour ICS-formoterol SMART\/MART for asthma.<\/p>\n<h3>How fast does Duolin work?<\/h3>\n<p>Levosalbutamol begins bronchodilation in 1\u20135 minutes; ipratropium adds in 15\u201330 minutes. Total combined duration 4\u20136 hours.<\/p>\n<h3>How often can I use Duolin?<\/h3>\n<p>Up to 4\u00d7 daily routinely; back-to-back every 20 minutes \u00d73 in severe attacks under supervision.<\/p>\n<h3>Can children use Duolin?<\/h3>\n<p>Yes in age-appropriate strength under medical supervision. Often used in paediatric A&#038;E for moderate-severe asthma attacks.<\/p>\n<h3>Is Duolin safe in pregnancy?<\/h3>\n<p>Both molecules have reassuring pregnancy data. Uncontrolled asthma is more dangerous than the combination.<\/p>\n<h3>Why dry mouth on Duolin?<\/h3>\n<p>Anticholinergic effect from ipratropium. Sips of water, gum, oral hygiene help.<\/p>\n<h3>Can I use Duolin Respules with budesonide?<\/h3>\n<p>Yes \u2014 co-nebulising Duolin with Budecort Respules in the same cup is common in moderate-to-severe acute attacks. Empty all respules into the cup; nebulise as one session.<\/p>\n<h3>Is Duolin a maintenance therapy?<\/h3>\n<p>It can be used regularly in COPD as 4\u00d7 daily maintenance, though modern guidelines prefer once-daily LAMA (Tiova, Airz) \u00b1 LABA. For asthma, regular use of SABA-containing relievers is no longer recommended \u2014 switch to ICS-LABA.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03c5\u03b8\u03cd\u03bd\u03b7\u03c2:<\/strong> \u0391\u03c5\u03c4\u03ae \u03b7 \u03c3\u03b5\u03bb\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c0\u03b1\u03b3\u03b3\u03b5\u03bb\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae. \u03a3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03b5\u03c5\u03c4\u03b5\u03af\u03c4\u03b5 \u03c0\u03ac\u03bd\u03c4\u03b1 \u03ad\u03bd\u03b1\u03bd \u03ba\u03b1\u03c4\u03b1\u03bb\u03bb\u03ae\u03bb\u03c9\u03c2 \u03b5\u03be\u03bf\u03c0\u03bb\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b1\u03b3\u03b3\u03b5\u03bb\u03bc\u03b1\u03c4\u03af\u03b1 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 \u03c0\u03c1\u03b9\u03bd \u03be\u03b5\u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03c4\u03b5, \u03c3\u03c4\u03b1\u03bc\u03b1\u03c4\u03ae\u03c3\u03b5\u03c4\u03b5 \u03ae \u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03c4\u03b5 \u03bf\u03c0\u03bf\u03b9\u03bf\u03bd\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b5\u03b9\u03c3\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03ae\u03c1\u03b1 \u03ae \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b1\u03bd \u03ad\u03c7\u03b5\u03c4\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2, \u03c0\u03b1\u03af\u03c1\u03bd\u03b5\u03c4\u03b5 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c3\u03c5\u03bd\u03c4\u03b1\u03b3\u03ad\u03c2, \u03b5\u03af\u03c3\u03c4\u03b5 \u03ad\u03b3\u03ba\u03c5\u03bf\u03c2 \u03ae \u03b8\u03b7\u03bb\u03ac\u03b6\u03b5\u03c4\u03b5, \u03ae \u03b5\u03af\u03c3\u03c4\u03b5 \u03ac\u03bd\u03c9 \u03c4\u03c9\u03bd 65 \u03b5\u03c4\u03ce\u03bd.<\/div>","protected":false},"excerpt":{"rendered":"<h5>\u2705 Effective asthma control<br \/>\n\u2705 Convenient respule format<br \/>\n\u2705 Easy inhalation method<br \/>\n\u2705 \u0392\u03b5\u03bb\u03c4\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b1\u03bd\u03b1\u03c0\u03bd\u03b5\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03ac\u03bd\u03b5\u03c3\u03b7<\/h5>\n<p><span style=\"color: #999999;\">Contains Levosalbutamol and Ipratropium Bromide<\/span><\/p>","protected":false},"featured_media":54321,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[3711,3709,3710],"class_list":{"0":"post-54320","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-duolin-respules","10":"product_tag-ipratropium-bromide","11":"product_tag-levosalbutamol","13":"first","14":"outofstock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/54320","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=54320"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/54321"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=54320"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=54320"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=54320"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=54320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}