{"id":55098,"date":"2023-11-22T09:09:58","date_gmt":"2023-11-22T09:09:58","guid":{"rendered":"https:\/\/medsname.com\/abd-400-albendazole\/"},"modified":"2026-04-30T17:13:31","modified_gmt":"2026-04-30T17:13:31","slug":"abd-400-albendazole","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/abd-400-albendazole\/","title":{"rendered":"ABD 400 (\u0391\u03bb\u03bc\u03c0\u03b5\u03bd\u03b4\u03b1\u03b6\u03cc\u03bb\u03b7)"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is ABD 400?<\/h3>\n<p style=\"margin:0;\"><strong>ABD 400<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>albendazole 400&nbsp;mg<\/strong> oral tablet &mdash; a broad-spectrum antiparasitic active against <strong>roundworm, pinworm, hookworm, whipworm, tapeworm, hydatid disease, and neurocysticercosis<\/strong>. Standard adult dose is a single 400&nbsp;mg tablet for most intestinal worms, repeated at 2 weeks. For hydatid disease and neurocysticercosis, longer courses are required. Take <strong>\u03bc\u03b5 \u03c0\u03bb\u03bf\u03cd\u03c3\u03b9\u03bf \u03c3\u03b5 \u03bb\u03b9\u03c0\u03b1\u03c1\u03ac \u03b3\u03b5\u03cd\u03bc\u03b1<\/strong> &mdash; absorption rises 5-fold.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase:<\/strong> \u2713 \u03a0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc <strong>WHO-GMP \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2<\/strong> \u00b7 \u2713 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u2713 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 \u2713 <strong>1,400+ \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/strong> \u03c3\u03c4\u03bf <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<p><strong>ABD 400<\/strong> is a Zydus <strong>albendazole 400&nbsp;mg<\/strong> oral tablet &mdash; a cornerstone antiparasitic medication for intestinal worms and selected tissue-cyst infections. Albendazole is a <strong>benzimidazole antihelminthic<\/strong> with one of the broadest spectra in its class, effective against adult worms, larvae, and in several cases the egg stage.<\/p>\n<p>ABD 400 is on the <strong>\u03a0\u03c1\u03cc\u03c4\u03c5\u03c0\u03bf \u039a\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf \u0392\u03b1\u03c3\u03b9\u03ba\u03ce\u03bd \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c4\u03bf\u03c5 WHO<\/strong> and is the backbone of most global deworming campaigns, including school-based mass drug administration programmes that have reduced soil-transmitted helminth prevalence in children across Asia, Africa, and Latin America.<\/p>\n<h2 class=\"wp-block-heading\">What Is ABD 400?<\/h2>\n<p>ABD 400 is a prescription <strong>benzimidazole antihelminthic<\/strong> with activity against the organisms that cause most human worm infections:<\/p>\n<ul>\n<li><strong>Nematodes (roundworms):<\/strong> <em>Ascaris lumbricoides<\/em>, <em>Enterobius vermicularis<\/em> (pinworm), <em>Trichuris trichiura<\/em> (whipworm), <em>Ancylostoma duodenale<\/em> \u03ba\u03b1\u03b9 <em>Necator americanus<\/em> (hookworms), <em>Strongyloides stercoralis<\/em><\/li>\n<li><strong>Cestodes (tapeworms):<\/strong> <em>Taenia solium<\/em>, <em>Taenia saginata<\/em>, and tissue cysts in neurocysticercosis and hydatid disease (<em>Echinococcus<\/em>)<\/li>\n<li><strong>Protozoa:<\/strong> some activity against <em>Giardia<\/em> \u03ba\u03b1\u03b9 <em>Microsporidia<\/em><\/li>\n<\/ul>\n<p>ABD 400 is not meaningfully active against trematodes (flukes) &mdash; praziquantel is preferred for schistosomiasis and most fluke infections.<\/p>\n<p>For scabies, head lice, strongyloidiasis, and onchocerciasis, <a href=\"https:\/\/medsbase.com\/el\/ivermectol\/\" rel=\"noopener\">ivermectin<\/a> is the first-line choice. See our comprehensive side-by-side guide: <a href=\"https:\/\/medsbase.com\/el\/ivermectin-vs-albendazole\/\" rel=\"noopener\">Ivermectin vs Albendazole: Which to Choose?<\/a><\/p>\n<h2 class=\"wp-block-heading\">How Does ABD 400 Work?<\/h2>\n<p>Albendazole exerts a selective, well-characterised antiparasitic effect:<\/p>\n<ul>\n<li>After absorption, it is rapidly converted in the liver to its active metabolite <strong>\u03b1\u03bb\u03b2\u03b5\u03bd\u03b4\u03b1\u03b6\u03cc\u03bb\u03b7 \u03c3\u03bf\u03c5\u03bb\u03c6\u03bf\u03be\u03b5\u03af\u03b4\u03b9\u03bf<\/strong><\/li>\n<li>The sulfoxide binds to parasite <strong>\u03b2-\u03c4\u03bf\u03c5\u03bc\u03c0\u03bf\u03c5\u03bb\u03af\u03bd\u03b7<\/strong>, inhibiting the polymerisation of microtubules<\/li>\n<li>Without functional microtubules, the parasite cannot maintain its glucose uptake or cellular structure &mdash; worm cells become starved of ATP and die<\/li>\n<li>Mammalian &beta;-tubulin has a different binding site, which is why albendazole is safe for humans at standard doses<\/li>\n<li>Oral absorption is <strong>poor on an empty stomach<\/strong> (&lt;5%) but increases <strong>5-fold<\/strong> with a fatty meal &mdash; critical for tissue-stage infections (hydatid, neurocysticercosis)<\/li>\n<\/ul>\n<p>Plasma half-life of albendazole sulfoxide is 8&ndash;12 hours. For intestinal worms, a single dose is usually enough; for tissue-stage disease, courses of weeks to months are required.<\/p>\n<h2 class=\"wp-block-heading\">\u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Ascariasis (roundworm)<\/strong> &mdash; single 400 mg dose, &gt;95% cure<\/li>\n<li><strong>Enterobiasis (pinworm \/ threadworm)<\/strong> &mdash; single dose, repeat at 2 weeks; treat all household contacts<\/li>\n<li><strong>Hookworm<\/strong> (<em>Ancylostoma<\/em>, <em>Necator<\/em>) &mdash; single dose; 3-day course for heavy load<\/li>\n<li><strong>Trichuriasis (whipworm)<\/strong> &mdash; 400 mg daily for 3 days gives higher cure than single dose<\/li>\n<li><strong>Strongyloidiasis<\/strong> &mdash; albendazole works, but <a href=\"https:\/\/medsbase.com\/el\/ivermectol\/\" rel=\"noopener\">ivermectin<\/a> is preferred as first-line<\/li>\n<li><strong>Taeniasis<\/strong> (tapeworm) &mdash; 400 mg daily for 3 days<\/li>\n<li><strong>Neurocysticercosis<\/strong> (brain cysts from <em>T. solium<\/em>) &mdash; 15 mg\/kg\/day in divided doses for 8&ndash;30 days with corticosteroid cover<\/li>\n<li><strong>Hydatid disease<\/strong> (<em>E. granulosus<\/em>) &mdash; 400 mg twice daily for 28-day courses, often multiple cycles<\/li>\n<li><strong>Giardiasis<\/strong> &mdash; alternative to metronidazole or tinidazole<\/li>\n<li><strong>Mass drug administration programmes<\/strong> &mdash; annual or biannual single-dose deworming in endemic regions<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">ABD 400 Dosage and Administration<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th>Adult Dose<\/th>\n<th>Schedule<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Ascariasis, hookworm, pinworm<\/strong><\/td>\n<td>400 mg<\/td>\n<td>Single dose; repeat at 2 weeks for pinworm to cover egg re-cycling<\/td>\n<\/tr>\n<tr>\n<td><strong>Whipworm (trichuriasis)<\/strong><\/td>\n<td>400 mg<\/td>\n<td>Once daily for 3 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Tapeworm (<em>Taenia<\/em>)<\/strong><\/td>\n<td>400 mg<\/td>\n<td>Once daily for 3 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Strongyloidiasis<\/strong><\/td>\n<td>400 mg<\/td>\n<td>Twice daily for 7 days (ivermectin is preferred first-line)<\/td>\n<\/tr>\n<tr>\n<td><strong>Hydatid disease<\/strong><\/td>\n<td>400 mg<\/td>\n<td>Twice daily &times; 28-day course; typically 3 cycles with 14-day breaks<\/td>\n<\/tr>\n<tr>\n<td><strong>Neurocysticercosis<\/strong><\/td>\n<td>15 mg\/kg\/day<\/td>\n<td>Divided every 12 hours for 8&ndash;30 days; with steroid and anticonvulsant cover<\/td>\n<\/tr>\n<tr>\n<td><strong>Giardiasis<\/strong><\/td>\n<td>400 mg<\/td>\n<td>Once daily for 5 days<\/td>\n<\/tr>\n<tr>\n<td><strong>Children &ge;2 years (intestinal worms)<\/strong><\/td>\n<td>400 mg<\/td>\n<td>Same as adult &mdash; mass-drug-administration dose in school-age children<\/td>\n<\/tr>\n<tr>\n<td><strong>Children 1&ndash;2 years<\/strong><\/td>\n<td>200 mg<\/td>\n<td>Half tablet for pinworm \/ ascariasis<\/td>\n<\/tr>\n<tr>\n<td><strong>\u0397\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/strong><\/td>\n<td>Caution; monitor LFTs<\/td>\n<td>Albendazole and its metabolite accumulate<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"wp-block-heading\">How to Take ABD 400 Properly<\/h3>\n<ul>\n<li>\u039a\u03b1\u03c4\u03b1\u03c0\u03b9\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf \u03bc\u03b5 \u03bd\u03b5\u03c1\u03cc<\/li>\n<li><strong>Take with a fatty meal<\/strong> &mdash; albendazole absorption rises 5-fold with fat, which is particularly important for hydatid disease and neurocysticercosis<\/li>\n<li>For pinworm, <strong>treat the whole household simultaneously<\/strong> and repeat the dose at 2 weeks &mdash; otherwise re-infection from egg recycling is almost guaranteed<\/li>\n<li>Wash bedding, clothing, and towels in hot water; short fingernails; hand hygiene after toilet and before meals<\/li>\n<li>For long-course therapy (hydatid disease, neurocysticercosis), <strong>monitor liver function and blood count<\/strong> monthly &mdash; reversible hepatotoxicity and bone-marrow suppression can occur<\/li>\n<li>Children with pinworm may need repeated courses because pinworm eggs can survive in bedding and carpets for 2&ndash;3 weeks; deep cleaning reduces re-infection risk<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Side Effects of ABD 400<\/h2>\n<p>Single-dose or short courses of ABD 400 are very well tolerated. Longer courses (hydatid, neurocysticercosis) carry higher risk.<\/p>\n<table>\n<thead>\n<tr>\n<th>\u0392\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1<\/th>\n<th>\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Common (&ge;1 in 100) &mdash; short courses<\/strong><\/td>\n<td>Mild nausea, abdominal discomfort, headache, dizziness, transient rise in liver enzymes<\/td>\n<\/tr>\n<tr>\n<td><strong>Common with long courses (weeks&ndash;months)<\/strong><\/td>\n<td>More pronounced liver enzyme elevation, mild reversible hair loss, leucopenia<\/td>\n<\/tr>\n<tr>\n<td><strong>\u0391\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03b5\u03c2<\/strong><\/td>\n<td>Rash, pruritus, vomiting, fever<\/td>\n<\/tr>\n<tr>\n<td><strong>Neurocysticercosis-specific<\/strong><\/td>\n<td>Inflammatory reaction as cysts die &mdash; worsening headache, seizures, focal neurological symptoms. Always co-administer with corticosteroid cover under specialist supervision<\/td>\n<\/tr>\n<tr>\n<td><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae<\/strong><\/td>\n<td>Severe hepatitis, bone-marrow suppression (pancytopenia, agranulocytosis), Stevens-Johnson syndrome<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u0396\u03b7\u03c4\u03ae\u03c3\u03c4\u03b5 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b2\u03bf\u03ae\u03b8\u03b5\u03b9\u03b1<\/strong> for yellowing of the eyes or skin, severe abdominal pain, unexplained bruising, unusual bleeding, severe widespread rash, or new-onset neurological symptoms during neurocysticercosis treatment.<\/p>\n<h2 class=\"wp-block-heading\">\u03a0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03ac\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7.<\/strong> Albendazole is teratogenic in animal studies. <strong>Avoid in the first trimester<\/strong>. WHO considers single-dose treatment for soil-transmitted helminths acceptable from the second trimester in endemic areas<\/li>\n<li><strong>Pre-pregnancy.<\/strong> Women of childbearing potential should have a negative pregnancy test before starting long courses (hydatid, neurocysticercosis) and use effective contraception throughout treatment and for 1 month after<\/li>\n<li><strong>\u0398\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2.<\/strong> Small amounts pass into breast milk; single-dose treatment is considered acceptable. Avoid long courses while breastfeeding where possible<\/li>\n<li><strong>Long-course monitoring.<\/strong> Monthly full blood count and LFTs during hydatid or neurocysticercosis treatment<\/li>\n<li><strong>Neurocysticercosis.<\/strong> Never initiate without steroid cover &mdash; dying cysts provoke cerebral oedema and can precipitate seizures or obstructive hydrocephalus. Start under specialist supervision in hospital<\/li>\n<li><strong>Hepatic impairment.<\/strong> Use with caution; consider dose reduction and monitor LFTs<\/li>\n<li><strong>Children under 1 year.<\/strong> Limited safety data &mdash; use only if clearly needed<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications &mdash; Who Should NOT Take ABD 400<\/h2>\n<ul>\n<li>Known hypersensitivity to albendazole or any benzimidazole<\/li>\n<li>First trimester of pregnancy<\/li>\n<li>Severe hepatic impairment (relative)<\/li>\n<li>Pre-existing bone-marrow suppression for long-course therapy<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \/ \u03a4\u03ac\u03be\u03b7<\/th>\n<th>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Dexamethasone, prednisolone<\/strong><\/td>\n<td>Commonly co-prescribed in neurocysticercosis &mdash; raise albendazole sulfoxide levels by ~50%, clinically beneficial<\/td>\n<\/tr>\n<tr>\n<td><strong>Praziquantel<\/strong><\/td>\n<td>Raises albendazole sulfoxide levels; often co-prescribed for mixed infections<\/td>\n<\/tr>\n<tr>\n<td><strong>\u0397 Cimetidine<\/strong><\/td>\n<td>Raises albendazole levels &mdash; sometimes used intentionally to boost hydatid cyst penetration<\/td>\n<\/tr>\n<tr>\n<td><strong>Phenytoin, carbamazepine, phenobarbital<\/strong><\/td>\n<td>Induce CYP metabolism &mdash; lower albendazole levels and may reduce efficacy in neurocysticercosis (where these anticonvulsants are often used)<\/td>\n<\/tr>\n<tr>\n<td><strong>Ritonavir<\/strong><\/td>\n<td>Raises albendazole levels &mdash; generally clinically manageable<\/td>\n<\/tr>\n<tr>\n<td><strong>\u0399\u03b2\u03b5\u03c1\u03bc\u03b5\u03ba\u03c4\u03af\u03bd\u03b7<\/strong><\/td>\n<td>No pharmacokinetic concern &mdash; commonly combined for lymphatic filariasis and broad deworming (see <a href=\"https:\/\/medsbase.com\/el\/bandy-plus\/\" rel=\"noopener\">Bandy-Plus<\/a>)<\/td>\n<\/tr>\n<tr>\n<td><strong>\u03a7\u03c5\u03bc\u03cc\u03c2 \u03b3\u03ba\u03c1\u03ad\u03b9\u03c0\u03c6\u03c1\u03bf\u03c5\u03c4<\/strong><\/td>\n<td>Can raise albendazole sulfoxide levels modestly &mdash; avoid large intake with long-course therapy<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Tell your doctor about all prescription and non-prescription medications, including herbal supplements, before starting ABD 400.<\/p>\n<h2 class=\"wp-block-heading\">\u03a4\u03b9 \u03bd\u03b1 \u039a\u03ac\u03bd\u03b5\u03c4\u03b5 \u03c3\u03b5 \u03a0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03a5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2<\/h2>\n<p>Acute overdose typically causes gastrointestinal upset only. There is no specific antidote. Management is supportive. Contact your local poisons service for large ingestions or paediatric accidental overdose.<\/p>\n<h2 class=\"wp-block-heading\">\u039f\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2<\/h2>\n<ul>\n<li>\u0391\u03c0\u03bf\u03b8\u03b7\u03ba\u03b5\u03cd\u03c3\u03c4\u03b5 \u03c3\u03b5 \u03b8\u03b5\u03c1\u03bc\u03bf\u03ba\u03c1\u03b1\u03c3\u03af\u03b1 \u03ba\u03ac\u03c4\u03c9 \u03b1\u03c0\u03cc 30\u00b0C \u03c3\u03b5 \u03be\u03b7\u03c1\u03cc \u03bc\u03ad\u03c1\u03bf\u03c2, \u03bc\u03b1\u03ba\u03c1\u03b9\u03ac \u03b1\u03c0\u03cc \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b7\u03bb\u03b9\u03b1\u03ba\u03ae \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b2\u03bf\u03bb\u03af\u03b1<\/li>\n<li>\u0394\u03b9\u03b1\u03c4\u03b7\u03c1\u03ae\u03c3\u03c4\u03b5 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u03c6\u03c5\u03c3\u03b1\u03bb\u03af\u03b4\u03c9\u03bd<\/li>\n<li>\u039c\u03b1\u03ba\u03c1\u03b9\u03ac \u03b1\u03c0\u03cc \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac<\/li>\n<li>\u039c\u03b7\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b5 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03b5\u03c1\u03bf\u03bc\u03b7\u03bd\u03af\u03b1 \u03bb\u03ae\u03be\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03b3\u03c1\u03ac\u03c6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/li>\n<li>\u0391\u03c0\u03bf\u03c1\u03c1\u03af\u03c8\u03c4\u03b5 \u03c4\u03b1 \u03b1\u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c4\u03b1 \u03b4\u03b9\u03c3\u03ba\u03af\u03b1 \u03bc\u03ad\u03c3\u03c9 \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03c0\u03b9\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae\u03c2 \u03c3\u03b5 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03af\u03bf, \u03cc\u03c0\u03bf\u03c5 \u03b1\u03c5\u03c4\u03cc \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u039b\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf MedsBase<\/h2>\n<p>Looking for related antiparasitic options?<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/wormentel\/\" rel=\"noopener\">Wormentel<\/a> &mdash; alternative albendazole brand<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/bandy-plus\/\" rel=\"noopener\">Bandy-Plus<\/a> &mdash; albendazole + ivermectin combination for broad-spectrum deworming<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/mebex\/\" rel=\"noopener\">Mebex<\/a> &mdash; mebendazole, a related benzimidazole alternative<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/ivermectol\/\" rel=\"noopener\">Ivermectol<\/a> &mdash; ivermectin, preferred for scabies and strongyloidiasis<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/iverjohn\/\" rel=\"noopener\">Iverjohn<\/a> &mdash; alternative ivermectin brand<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/iverheal\/\" rel=\"noopener\">Iverheal<\/a> &mdash; Healing Pharma ivermectin<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/ivermectin-vs-albendazole\/\" rel=\"noopener\">Guide: Ivermectin vs Albendazole &mdash; which to choose<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/parasitic-infections\/\" rel=\"noopener\">Browse all Parasitic Infection treatments &rarr;<\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">What is ABD 400 used for?<\/h3>\n<p>ABD 400 is an <strong>albendazole 400 mg<\/strong> tablet used for <strong>roundworm, pinworm, hookworm, whipworm, tapeworm, hydatid disease, neurocysticercosis, and giardiasis<\/strong>. It is one of the most widely prescribed antiparasitics worldwide.<\/p>\n<h3 class=\"wp-block-heading\">How should I take ABD 400?<\/h3>\n<p>\u039a\u03b1\u03c4\u03b1\u03c0\u03b9\u03b5\u03af\u03c4\u03b5 \u03c4\u03bf \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf \u03bc\u03b5 \u03ad\u03bd\u03b1 <strong>fatty meal<\/strong> &mdash; this increases absorption 5-fold. For pinworm, repeat the dose at 2 weeks and treat all household contacts simultaneously.<\/p>\n<h3 class=\"wp-block-heading\">Albendazole or ivermectin &mdash; which should I use?<\/h3>\n<p><strong>Albendazole<\/strong> is first-line for intestinal worms (roundworm, pinworm, hookworm, whipworm), tapeworm, hydatid disease, and neurocysticercosis. <strong>\u0399\u03b2\u03b5\u03c1\u03bc\u03b5\u03ba\u03c4\u03af\u03bd\u03b7<\/strong> is first-line for scabies, strongyloidiasis, onchocerciasis, and head lice. For a full comparison see our <a href=\"https:\/\/medsbase.com\/el\/ivermectin-vs-albendazole\/\" rel=\"noopener\">Ivermectin vs Albendazole guide<\/a>.<\/p>\n<h3 class=\"wp-block-heading\">How fast does ABD 400 work?<\/h3>\n<p>For intestinal worms, symptoms usually improve within <strong>24&ndash;72 hours<\/strong>. For tissue-stage disease (hydatid, neurocysticercosis) improvement takes weeks to months and is tracked on imaging, not symptoms.<\/p>\n<h3 class=\"wp-block-heading\">Why do I need a second dose after 2 weeks for pinworm?<\/h3>\n<p>Pinworm eggs can survive in the environment for 2&ndash;3 weeks. The first dose kills the adult worms but may not eliminate larvae that hatch from already-laid eggs. A second dose at 2 weeks catches the next generation before they can lay new eggs.<\/p>\n<h3 class=\"wp-block-heading\">Do I need to treat my whole family?<\/h3>\n<p><strong>Yes for pinworm<\/strong> &mdash; transmission is efficient within households. Everyone in the house should be treated on the same day and the repeat dose given to all simultaneously at 2 weeks. Wash bedding, towels, and clothing on the treatment day.<\/p>\n<h3 class=\"wp-block-heading\">Is ABD 400 safe in pregnancy?<\/h3>\n<p>Avoid in the <strong>first trimester<\/strong> due to teratogenic potential in animal studies. Single-dose treatment in the second and third trimesters is considered acceptable in endemic regions per WHO guidance. Use contraception during long-course therapy and for 1 month after.<\/p>\n<h3 class=\"wp-block-heading\">Can I give ABD 400 to children?<\/h3>\n<p>Yes &mdash; the 400 mg dose is standard for school-age children in mass-drug-administration programmes. For children aged 1&ndash;2 years, halve the dose (200 mg). Below age 1, use only if clearly needed under paediatric guidance.<\/p>\n<h3 class=\"wp-block-heading\">What if my symptoms don&#8217;t resolve?<\/h3>\n<p>Persistent symptoms after a single dose may mean: (a) wrong diagnosis (not a worm), (b) a worm not covered by albendazole (schistosoma &mdash; use praziquantel), (c) re-infection from untreated contacts or environment, (d) heavy infestation needing a 3-day course. Review with your doctor.<\/p>\n<h3 class=\"wp-block-heading\">Does ABD 400 treat scabies?<\/h3>\n<p>No &mdash; scabies is an ectoparasite (mite) and is treated with oral <a href=\"https:\/\/medsbase.com\/el\/ivermectol\/\" rel=\"noopener\">ivermectin<\/a> or topical permethrin. Albendazole has no useful activity against scabies.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol with ABD 400?<\/h3>\n<p>Moderate alcohol intake with short courses is usually fine. Avoid alcohol during long courses (hydatid disease, neurocysticercosis) because of additive hepatotoxic risk.<\/p>\n<p><!-- medsbase-faq-h3-converted --><\/p>\n<p class=\"medsbase-link-boost-2026-04-30\" data-marker=\"mb-link-boost-ivermectin-fenbendazole-combo-pack\">For users running protocols that specifically pair ivermectin with fenbendazole rather than albendazole, our <a href='\/el\/ivermectin-fenbendazole-combo-pack\/'>\u03a3\u03c5\u03bc\u03c0\u03b1\u03ba\u03c4\u03b9\u03ba\u03cc Ivermectin &amp; Fenbendazole<\/a> bundles those two molecules at a combined-pack price.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 <strong>\u0393\u03b5\u03bd\u03b9\u03ba\u03ae \u03a5\u03b3\u03b5\u03af\u03b1<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/placentrex-gel\/\">Placentrex Gel<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/lynx-injection\/\">Lynx Injection<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/clariford\/\">Clariford<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/azopt-eye-drops\/\">Azopt Eye Drops<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/cystone\/\">Cystone<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>ABD 400 (albendazole 400 mg) \u2014 broad-spectrum benzimidazole anthelmintic for pinworm, roundworm, hookworm, whipworm, and tissue-stage hydatid disease. Single-dose adult therapy from a WHO-GMP certified manufacturer.<\/p>","protected":false},"featured_media":55099,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3856],"product_tag":[5715,3857,5716,5707,5719,5722,5723,5718,5717,5721,5720],"class_list":{"0":"post-55098","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-threadworm-treatment","9":"product_tag-abd-400","10":"product_tag-albendazole","11":"product_tag-albenza-generic","12":"product_tag-antiparasitic","13":"product_tag-hookworm","14":"product_tag-hydatid-disease","15":"product_tag-neurocysticercosis","16":"product_tag-pinworm","17":"product_tag-roundworm","18":"product_tag-tapeworm","19":"product_tag-whipworm","21":"first","22":"instock","23":"shipping-taxable","24":"purchasable","25":"product-type-variable","26":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/55098","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=55098"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/55099"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=55098"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=55098"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=55098"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=55098"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}