{"id":55235,"date":"2024-01-12T20:18:33","date_gmt":"2024-01-12T20:18:33","guid":{"rendered":"https:\/\/medsname.com\/stemetil\/"},"modified":"2026-04-30T10:24:50","modified_gmt":"2026-04-30T10:24:50","slug":"stemetil","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/stemetil\/","title":{"rendered":"Stemetil"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Stemetil?<\/h3>\n<p style=\"margin:0;\"><strong>Stemetil<\/strong> is prochlorperazine maleate 5 mg &mdash; a phenothiazine first-generation antipsychotic widely used at low doses for <strong>severe nausea and vomiting, vertigo, Meniere&#8217;s disease, and the labyrinthine vertigo<\/strong> of inner-ear dysfunction. It blocks central D2 dopamine receptors in the chemoreceptor trigger zone (antiemetic) and in the labyrinth (anti-vertigo), and to a lesser extent histamine H1 and muscarinic receptors. Standard dose: <strong>5&ndash;10 mg three times daily orally for nausea or vertigo, max 30 mg\/day<\/strong>; bipolar\/schizophrenia at higher doses is rarely used today given atypical antipsychotic alternatives. WHO-GMP certified manufacturer.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f6f8;border:1px solid #e1e4e8;border-radius:6px;padding:14px 18px;margin:24px 0;font-size:14px;\"><strong>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase:<\/strong> \u2714 <strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong> &#10004; Discreet packaging &#10004; Worldwide shipping &#10004; <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">Verified customer reviews (1,400+ customers)<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\"><strong>&#9888;&#65039; FGA antipsychotic warnings.<\/strong> Prochlorperazine is a typical (first-generation) antipsychotic and shares the class warnings of acute dystonia, akathisia, parkinsonism, neuroleptic malignant syndrome, and tardive dyskinesia. Risk is dose-and-duration dependent; the antiemetic doses used for nausea\/vertigo are lower than antipsychotic doses but extrapyramidal effects still occur (notably in young men and elderly women). Increased mortality has been observed in elderly dementia patients on antipsychotics &mdash; avoid in this population. Avoid in Parkinson&#8217;s disease.<\/div>\n<h3 class=\"wp-block-heading\">\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Stemetil is supplied from a <strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong>. Every order ships discreetly worldwide and is covered by our <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> &mdash; if it does not arrive within 20 business days, we reship at no cost. Stemetil is a long-established antiemetic and vestibular suppressant used worldwide for severe nausea, vertigo, and Meniere&#39;s symptom flares.<\/p>\n<h2 class=\"wp-block-heading\">Mechanism<\/h2>\n<p>Prochlorperazine antagonises central D2 dopamine receptors. In the chemoreceptor trigger zone this produces a strong antiemetic effect (more potent than metoclopramide for severe vomiting). In the inner ear and brainstem vestibular nuclei it suppresses vertigo. H1 antagonism explains the sedation; muscarinic antagonism explains dry mouth. At higher doses it has the typical FGA pharmacology (positive-symptom psychosis suppression).<\/p>\n<h2 class=\"wp-block-heading\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li>Severe nausea and vomiting (chemo, post-op, migraine, gastroenteritis)<\/li>\n<li>Vertigo (vestibular neuronitis, BPPV with severe symptoms, Meniere&#39;s flare)<\/li>\n<li>Meniere&#8217;s disease symptom relief (combined with diuretic \/ dietary salt restriction)<\/li>\n<li>Labyrinthitis<\/li>\n<li>Schizophrenia (rarely &mdash; superseded by atypicals)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0394\u03cc\u03c3\u03b7<\/h2>\n<p>Adults: 5&ndash;10 mg three times daily orally for nausea\/vertigo. Acute migraine-associated nausea: 5&ndash;10 mg single dose. Meniere&#8217;s: 5 mg three times daily, titrate to symptom control (max 30 mg\/day). Children: avoid &lt; 10 kg. Hepatic impairment: reduce dose. Elderly: start at half-dose &mdash; very high EPS risk.<\/p>\n<h2 class=\"wp-block-heading\">\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li>Common: drowsiness, dry mouth, constipation, blurred vision, postural hypotension<\/li>\n<li>Extrapyramidal: acute dystonia (oculogyric crisis, torticollis), akathisia, parkinsonism, tardive dyskinesia<\/li>\n<li>Hyperprolactinaemia: galactorrhoea, menstrual changes<\/li>\n<li>QT prolongation, torsades de pointes (rare)<\/li>\n<li>Photosensitivity skin rash, cholestatic jaundice (idiosyncratic)<\/li>\n<li>Neuroleptic malignant syndrome (rare, life-threatening)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<ul>\n<li>Other dopamine antagonists (metoclopramide, haloperidol, atypicals): additive EPS &mdash; avoid stacking.<\/li>\n<li>QT-prolonging drugs (azithromycin, fluoroquinolones, ondansetron, citalopram, methadone): avoid combination.<\/li>\n<li>CNS depressants (alcohol, opioids, benzodiazepines): additive sedation, hypotension.<\/li>\n<li>Levodopa, dopamine agonists: each blocks the other&#39;s effect &mdash; avoid in Parkinson&#8217;s.<\/li>\n<li>Anticholinergics: additive dry mouth, urinary retention, constipation.<\/li>\n<\/ul>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">What is Stemetil mainly used for?<\/h3>\n<p>Severe nausea, vomiting, and vertigo. It is more potent than metoclopramide for severe vomiting and is the standard for vestibular vertigo flares.<\/p>\n<h3 class=\"wp-block-heading\">How quickly will it work?<\/h3>\n<p>Antiemetic effect within 30&ndash;60 minutes orally. The IM and rectal routes (5 mg or 25 mg suppositories) act within 30 minutes when the patient cannot keep tablets down.<\/p>\n<h3 class=\"wp-block-heading\">Is it safe to drive on this?<\/h3>\n<p>Drowsiness is common. Do not drive until you know how it affects you. The first 1&ndash;2 weeks are usually most sedating.<\/p>\n<h3 class=\"wp-block-heading\">Can I take it with my migraine medication?<\/h3>\n<p>Yes &mdash; prochlorperazine is often combined with triptans and analgesics during a migraine attack to control nausea. Avoid with QT-prolonging triptan combinations and tell the prescriber.<\/p>\n<h3 class=\"wp-block-heading\">Is it the same as metoclopramide?<\/h3>\n<p>Both are D2 antagonists. Prochlorperazine is more potent for severe vomiting and is preferred for vertigo. Metoclopramide is more prokinetic. Both share extrapyramidal side-effect risk.<\/p>\n<h3 class=\"wp-block-heading\">Why am I getting muscle spasms?<\/h3>\n<p>Acute dystonia is a recognised early side effect &mdash; uncontrolled muscle pulling in the neck, jaw, eyes, or trunk. Stop the drug and seek medical help. Treated with IV anticholinergic (procyclidine).<\/p>\n<h3 class=\"wp-block-heading\">Can I take it long-term for Meniere&#8217;s?<\/h3>\n<p>Short-to-medium courses for symptom flares are typical. Long-term use (months) raises tardive dyskinesia risk &mdash; specialist ENT\/neurology supervision recommended.<\/p>\n<h3 class=\"wp-block-heading\">\u0395\u03af\u03bd\u03b1\u03b9 \u03b1\u03c3\u03c6\u03b1\u03bb\u03ad\u03c2 \u03c3\u03c4\u03b7\u03bd \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7;<\/h3>\n<p>Category C. Sometimes used for severe hyperemesis gravidarum when first-line fails. Discuss with obstetric prescriber.<\/p>\n<h3 class=\"wp-block-heading\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h3>\n<p>Below 25&deg;C, away from light. Keep out of reach of children.<\/p>\n<h3 class=\"wp-block-heading\">\u03a4\u03b9 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03bd \u03c7\u03ac\u03c3\u03c9 \u03bc\u03b9\u03b1 \u03b4\u03cc\u03c3\u03b7;<\/h3>\n<p>Take it as soon as you remember. If close to the next dose, skip it. Do not double up.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Other Gastro Health Medications<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/dompewal-tablet\/\">Dompewal &mdash; Domperidone<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/reglan\/\">Reglan &mdash; Metoclopramide<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/doxinate\/\">Doxinate &mdash; Doxylamine + B6 (NVP-specific)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/zofer\/\">Zofer &mdash; Ondansetron (5-HT3 antiemetic)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/stugeron\/\">Stugeron &mdash; Cinnarizine (vertigo)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/gastro-health\/\"><strong>Browse all Gastro Health Medications<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u0391\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u0395\u03c5\u03b8\u03cd\u03bd\u03b7\u03c2.<\/strong> This page is for informational purposes only and does not replace medical advice from a qualified healthcare professional. Persistent vertigo or vomiting needs assessment for vestibular, cardiac, and neurological causes.<\/div>","protected":false},"excerpt":{"rendered":"<p>Stemetil (Prochlorperazine 5 mg) \u2014 phenothiazine antiemetic and vestibular suppressant for severe nausea, vomiting, vertigo, Meniere&#8217;s disease, and migraine-associated vomiting. WHO-GMP certified manufacturer. Worldwide shipping from MedsBase.<\/p>","protected":false},"featured_media":55236,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3542,3342],"product_tag":[3885,3886],"class_list":{"0":"post-55235","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-gastro-health","8":"product_cat-general-health","9":"product_tag-prochlorperazine-maleate","10":"product_tag-stemetil","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/55235","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=55235"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/55236"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=55235"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=55235"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=55235"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=55235"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}