{"id":55256,"date":"2024-01-14T09:11:30","date_gmt":"2024-01-14T09:11:30","guid":{"rendered":"https:\/\/medsname.com\/nimodip-nimodipine\/"},"modified":"2026-05-01T10:49:12","modified_gmt":"2026-05-01T10:49:12","slug":"nimodip-nimodipine","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/nimodip-nimodipine\/","title":{"rendered":"Nimodip (Nimodipine)"},"content":{"rendered":"

<\/p>\n

\n

⚡ Quick Answer — What is Nimodip?<\/h3>\n

\u039d\u03b9\u03bc\u03bf\u03bd\u03c4\u03af\u03c0<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 30 mg nimodipine tablet<\/strong> from a WHO-GMP certified manufacturer — a dihydropyridine CCB with selective cerebrovascular activity calcium-channel blocker (CCB). Introduced 1989 (Bayer as Nimotop<\/strong>) specifically for neurosurgical use. Unlike other DHPs, nimodipine has a high lipophilicity that allows it to cross the blood-brain barrier and act preferentially on cerebral arterial smooth muscle. Plasma half-life 1-2 hours (short) — requires 4-hourly dosing. Nimodipine is NOT a general antihypertensive — it is used specifically to prevent delayed cerebral ischaemia (vasospasm) after aneurysmal subarachnoid haemorrhage (aSAH)<\/strong>. Dose: 60 mg orally every 4 hours for 21 days, started within 96 hours of haemorrhage. For hypertension, use amlodipine<\/a> \u03ae \u03bd\u03b9\u03c6\u03b5\u03b4\u03b9\u03c0\u03af\u03bd\u03b7 \u03b5\u03c0\u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03b7\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2<\/a> \u03b1\u03bd\u03c4\u03af \u03b1\u03c5\u03c4\u03bf\u03cd.<\/p>\n<\/div>\n

\n\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n

\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n

\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n

\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n

What Is Nimodip?<\/h2>\n

Nimodip is an oral 30 mg nimodipine tablet from a WHO-GMP certified manufacturer, supplied in 30-180 tablets. Introduced 1989 (Bayer as Nimotop<\/strong>) specifically for neurosurgical use. Unlike other DHPs, nimodipine has a high lipophilicity that allows it to cross the blood-brain barrier and act preferentially on cerebral arterial smooth muscle.<\/p>\n

Nimodipine belongs to the \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03b7\u03b3\u03bf\u03c1\u03af\u03b1 \u03c4\u03c9\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03c9\u03bd \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03b9\u03b1\u03ba\u03ce\u03bd \u03ba\u03b1\u03bd\u03b1\u03bb\u03b9\u03ce\u03bd \u03b4\u03b9\u03c5\u03b4\u03c1\u03bf\u03c0\u03c5\u03c1\u03b9\u03b4\u03af\u03bd\u03b7\u03c2<\/strong> , \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b9\u03c2 \u03bc\u03b7 \u03b4\u03b9\u03c5\u03b4\u03c1\u03bf\u03c0\u03c5\u03c1\u03b9\u03b4\u03af\u03bd\u03b5\u03c2 (\u03b4\u03b9\u03bb\u03c4\u03b9\u03b1\u03b6\u03ad\u03bc\u03b7<\/a>, \u03b2\u03b5\u03c1\u03b1\u03c0\u03b1\u03bc\u03af\u03bb\u03b7<\/a>) \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03c0\u03b9\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bb\u03b5\u03af\u03bf\u03c5\u03c2 \u03bc\u03c5\u03c2 \u03c4\u03c9\u03bd \u03b1\u03b3\u03b3\u03b5\u03af\u03c9\u03bd \u03bc\u03b5 \u03b5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03b7 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/strong>. \u0391\u03c5\u03c4\u03cc \u03c4\u03bf \u03b5\u03c0\u03b9\u03bb\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc: \u03c4\u03b1 DHP \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03c4\u03bf\u03cd\u03bd \u03bc\u03b5 \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1 \u03bc\u03b5 \u03b2-\u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 (\u03bf \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03cc\u03c4\u03c5\u03c0\u03bf \u03c3\u03c4\u03b7 \u03c3\u03c4\u03b7\u03b8\u03ac\u03b3\u03c7\u03b7), \u03b5\u03bd\u03ce \u03c4\u03b1 \u03bc\u03b7 DHP \u03b4\u03b5\u03bd \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd (\u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b7\u03c2 \u03b2\u03c1\u03b1\u03b4\u03c5\u03ba\u03b1\u03c1\u03b4\u03af\u03b1\u03c2\/\u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b1\u03c3\u03c6\u03c5\u03be\u03af\u03b1\u03c2).<\/p>\n

How Nimodipine Works<\/h2>\n

\u039f\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 \u03b4\u03b9\u03b1\u03cd\u03bb\u03c9\u03bd \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5 \u03b4\u03b5\u03c3\u03bc\u03b5\u03cd\u03bf\u03c5\u03bd \u03c4\u03bf\u03c5\u03c2 \u03b4\u03b9\u03b1\u03cd\u03bb\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5 \u03c4\u03cd\u03c0\u03bf\u03c5 L \u03c0\u03bf\u03c5 \u03c1\u03c5\u03b8\u03bc\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03ac\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03b9\u03c3\u03c1\u03bf\u03ae \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5 \u03c3\u03c4\u03bf \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03bf \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03c0\u03bf\u03c0\u03cc\u03bb\u03c9\u03c3\u03b7\u03c2. \u03a3\u03c4\u03bf\u03c5\u03c2 \u03bb\u03b5\u03af\u03bf\u03c5\u03c2 \u03c4\u03c9\u03bd \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03ce\u03bd<\/strong>, \u03b7 \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03b5\u03af\u03c3\u03bf\u03b4\u03bf\u03c2 \u03b1\u03c3\u03b2\u03b5\u03c3\u03c4\u03af\u03bf\u03c5 \u03c3\u03b7\u03bc\u03b1\u03af\u03bd\u03b5\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03b1\u03ba\u03c4\u03af\u03bd\u03b7\u03c2-\u03bc\u03c5\u03bf\u03c3\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b4\u03b9\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03c9\u03bd \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03ce\u03bd<\/strong> \u2014 \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03b7\u03bd \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03b1\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c1\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03c0\u03af\u03b5\u03c3\u03b7.<\/p>\n

Dihydropyridines are ~10-fold more potent on vascular smooth muscle than on cardiac muscle — so the dominant clinical effect is vasodilation, with minimal direct suppression of cardiac contractility or conduction. The body’s baroreflex can trigger mild reflex tachycardia after fast-onset vasodilation; nimodipine acts centrally on cerebral arteries so reflex effects are less clinically relevant.<\/p>\n

Onset of clinical effect: rapid (15-30 minutes); peak plasma within 1 hour.<\/p>\n

\u0395\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03b1\u03b9 \u0392\u03b1\u03c3\u03b9\u03c3\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c3\u03b5 \u0391\u03c0\u03bf\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n