{"id":57275,"date":"2024-02-27T17:34:00","date_gmt":"2024-02-27T17:34:00","guid":{"rendered":"https:\/\/medsname.com\/halox-cream\/"},"modified":"2026-05-01T10:49:13","modified_gmt":"2026-05-01T10:49:13","slug":"halox-cream","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/halox-cream\/","title":{"rendered":"Halox Cream"},"content":{"rendered":"

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⚡ Quick Answer — What is Halox Cream?<\/h3>\n

Halox Cream<\/strong> is a topical halobetasol propionate 0.05%<\/strong> cream from Systopic Laboratories — a super-potent \/ very-potent topical corticosteroid (UK Class IV \/ US Class I, the most potent tier)<\/strong>. It is reserved for severe, short-course, steroid-responsive dermatoses<\/strong> where a potent steroid has failed: thick plaque psoriasis, severe atopic dermatitis flares, lichen simplex chronicus, hypertrophic lichen planus, discoid lupus, cutaneous sarcoidosis. Apply a thin film once or twice daily<\/strong>. Maximum course is 2 weeks at a time, 50 g per week<\/strong> — then step down to a less potent steroid or a steroid-sparing alternative. Absolutely not for face, eyelids, armpits, groin, under occlusion, or in children under 12<\/strong>. Not a rosacea treatment — super-potent steroids on the face cause steroid-induced rosacea, irreversible atrophy, and telangiectasia.<\/p>\n<\/div>\n

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What Is Halox Cream?<\/h2>\n

Halox Cream is a 0.05% halobetasol propionate<\/strong> topical cream, manufactured by Systopic Laboratories and supplied in a 15 g tube. Halobetasol is a synthetic halogenated glucocorticoid classified as a super-potent \/ very-potent topical corticosteroid<\/strong> — the most powerful tier on the topical steroid ladder, alongside clobetasol propionate 0.05%. Super-potent steroids are reserved for severe flares that have not responded to a potent (Class III) steroid<\/strong> like mometasone or betamethasone valerate 0.1%.<\/p>\n

Topical Steroid Potency Ladder<\/h2>\n\n\n\n\n\n\n\n\n
UK Class<\/th>\nUS Class<\/th>\n\u0399\u03c3\u03c7\u03cd\u03c2<\/th>\nExamples<\/th>\n<\/tr>\n<\/thead>\n
I<\/td>\nVII<\/td>\nMild<\/td>\nHydrocortisone 0.5–1%<\/td>\n<\/tr>\n
II<\/td>\nVI-V<\/td>\n\u039c\u03ad\u03c4\u03c1\u03b9\u03bf<\/td>\nClobetasone butyrate, betamethasone valerate 0.025%<\/td>\n<\/tr>\n
III<\/td>\nIII-II<\/td>\nPotent<\/td>\nMometasone 0.1%, fluticasone, betamethasone valerate 0.1%<\/td>\n<\/tr>\n
IV<\/td>\nI<\/td>\nSuper-potent<\/td>\nHalobetasol propionate 0.05% (Halox Cream)<\/strong>, clobetasol propionate 0.05%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Halox Cream is 5–10× more potent<\/strong> than a Class III steroid, with proportionally higher risk of atrophy, telangiectasia, striae, and HPA-axis suppression. It is used in dermatology specifically to deliver a fast, decisive strike on a severe flare — then step down.<\/p>\n

Appropriate Uses<\/h2>\n