{"id":57281,"date":"2024-02-27T17:34:41","date_gmt":"2024-02-27T17:34:41","guid":{"rendered":"https:\/\/medsname.com\/ashvagandha\/"},"modified":"2026-04-30T10:24:29","modified_gmt":"2026-04-30T10:24:29","slug":"ashvagandha","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/ashvagandha\/","title":{"rendered":"Ashvagandha"},"content":{"rendered":"

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\u26a1 \u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u0391\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7<\/h3>\n

Ashvagandha (Withania somnifera root extract 250 \/ 500 mg root extract) is an Ayurvedic adaptogenic herbal supplement traditionally used for stress, sleep, and general vitality. Modern small RCTs suggest a modest benefit for stress and subjective sleep \u2014 not a substitute for prescription antidepressants or hypnotics in diagnosed disease.<\/p>\n<\/div>\n

\n\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n

\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n

\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n

Ashvagandha at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> \u2014 \u03c0\u03b1\u03c1\u03ac\u03b8\u03c5\u03c1\u03bf \u03ac\u03c6\u03b9\u03be\u03b7\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd \u03ae \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c7\u03c9\u03c1\u03af\u03c2 \u03c7\u03c1\u03ad\u03c9\u03c3\u03b7 \u2014 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03ba\u03b1\u03b9\u03bf\u03cd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03c3\u03c4\u03bf \u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1 \u03b1\u03c6\u03bf\u03c3\u03af\u03c9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>. \u0394\u03b9\u03b1\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03c1\u03bf\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2.<\/p>\n

\nImportant \u2014 supplement, not a substitute for medical treatment<\/strong><\/p>\n

Ashwagandha is a traditional Ayurvedic herb with modest modern trial evidence for stress and subjective sleep quality. It is not a substitute<\/strong> for SSRIs\/SNRIs in major depression, for benzodiazepines or buspirone in diagnosed anxiety disorder, or for sleep hygiene plus appropriate hypnotic in chronic insomnia. If symptoms persist beyond 6\u20138 weeks, see a clinician.<\/p>\n<\/div>\n

What Ashvagandha is and how it might work<\/h2>\n

Ashvagandha is a 250 \/ 500 mg root extract Withania somnifera root extract supplied by Himalaya. Ashwagandha (also called Indian ginseng<\/em> \u03ae winter cherry<\/em>) is an adaptogenic herb used in Ayurvedic medicine for over 3,000 years. The active constituents are withanolides \u2014 steroidal lactones with weak GABAergic activity, antioxidant action, and modulating effects on the HPA axis (the body’s stress-response circuit).<\/p>\n

Modern small RCTs (Chandrasekhar 2012, Lopresti 2019, others) suggest moderate reductions in subjective stress scores, salivary cortisol, and self-rated sleep quality \u2014 but trial sizes are small (40\u2013125 patients), follow-up is short (60\u201390 days), and effect sizes are modest. The herbal-supplement evidence base is far behind the SSRI evidence base.<\/p>\n

\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1<\/h2>\n\n\n\n\n\n\n\n\n
\u03a7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03c4\u03b5<\/th>\nTypical dose<\/th>\n\u03a3\u03b7\u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9\u03c2<\/th>\n<\/tr>\n<\/thead>\n
General stress \/ vitality<\/td>\n300\u2013600 mg\/day extract<\/td>\nLook for standardised withanolide content (\u2265 5%)<\/td>\n<\/tr>\n
Subjective sleep quality<\/td>\n300 mg HS<\/td>\nSome evidence in modern RCTs<\/td>\n<\/tr>\n
Anxiety adjunct (off-label)<\/td>\n500\u2013600 mg\/day in 2 doses<\/td>\nNot a substitute for SSRI in diagnosed GAD<\/td>\n<\/tr>\n
Athletic recovery \/ fatigue<\/td>\n500 mg\/day<\/td>\nMixed evidence<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Take with food. Allow 4\u20138 weeks for subjective effects to develop.<\/p>\n

\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c3\u03c6\u03b1\u03bb\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03ba\u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n
\nPregnancy and breastfeeding \u2014 avoid<\/strong><\/p>\n

Ashwagandha has historical Ayurvedic use as an abortifacient at high doses. Avoid in pregnancy. Insufficient data in lactation \u2014 generally avoided.<\/p>\n<\/div>\n

\nThyroid stimulation<\/strong><\/p>\n

Ashwagandha can raise T3\/T4 levels \u2014 useful in subclinical hypothyroidism but problematic in hyperthyroidism, Graves’ disease, and when on levothyroxine (can raise the effective dose). Check TSH if symptoms suggest thyroid imbalance.<\/p>\n<\/div>\n

\nAutoimmune disease<\/strong><\/p>\n

Ashwagandha is an immunomodulator and may worsen autoimmune flare in lupus, RA, MS, Hashimoto’s. Avoid or use cautiously.<\/p>\n<\/div>\n

\nSedatives, benzodiazepines, barbiturates<\/strong><\/p>\n

Mild GABAergic action \u2014 additive sedation when combined.<\/p>\n<\/div>\n

\nRecent reports of hepatotoxicity<\/strong><\/p>\n

Rare cases of cholestatic hepatitis have been reported with high-dose ashwagandha. Stop and seek medical advice if jaundice, dark urine, or RUQ pain develop.<\/p>\n<\/div>\n

\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n