{"id":57635,"date":"2024-02-27T17:53:27","date_gmt":"2024-02-27T17:53:27","guid":{"rendered":"https:\/\/medsname.com\/antidep\/"},"modified":"2026-04-30T10:24:24","modified_gmt":"2026-04-30T10:24:24","slug":"antidep","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/antidep\/","title":{"rendered":"Antidep"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8d6;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">\u26a1 \u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u0391\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7<\/h3>\n<p style=\"margin-bottom:0;\">Antidep (Imipramine 25 \/ 75 mg) is a tricyclic antidepressant. Used for major depression, panic disorder, and (uniquely) paediatric nocturnal enuresis. Higher tolerability burden than SSRIs \u2014 second-line for most patients.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Antidep at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> \u2014 \u03c0\u03b1\u03c1\u03ac\u03b8\u03c5\u03c1\u03bf \u03ac\u03c6\u03b9\u03be\u03b7\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd \u03ae \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c7\u03c9\u03c1\u03af\u03c2 \u03c7\u03c1\u03ad\u03c9\u03c3\u03b7 \u2014 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03ba\u03b1\u03b9\u03bf\u03cd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03c3\u03c4\u03bf <a href=\"https:\/\/medsbase.com\/el\/loyalty-points\/\">\u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1 \u03b1\u03c6\u03bf\u03c3\u03af\u03c9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>. \u0394\u03b9\u03b1\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03c1\u03bf\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2.<\/p>\n<h2>What Antidep is and how it works<\/h2>\n<p>Antidep is a Imipramine-containing tablet supplied by Intas. Available strengths: <strong>25 \/ 75 mg<\/strong>.<\/p>\n<p>Imipramine was the <strong>first tricyclic antidepressant<\/strong> (Geigy, 1957) and remains a useful agent for major depression where SSRIs have failed, panic disorder, and \u2014 uniquely \u2014 paediatric nocturnal enuresis (bedwetting) where behavioural measures have failed.<\/p>\n<p>Tricyclic antidepressants block the reuptake of serotonin and noradrenaline at presynaptic transporters, similar to SSRIs and SNRIs. Their tolerability disadvantage comes from <strong>off-target receptor blockade<\/strong>: muscarinic (anticholinergic side effects), histaminergic H1 (sedation, weight gain), and \u03b11-adrenergic (orthostatic hypotension). They also block fast sodium channels in cardiac tissue \u2014 the basis for both their analgesic action and their cardiac toxicity in overdose.<\/p>\n<p>Imipramine has the most balanced serotonin-noradrenaline reuptake inhibition of the TCAs and is the historical reference for newer agents.<\/p>\n<h2>\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th>\u0395\u03ba\u03ba\u03af\u03bd\u03b7\u03c3\u03b7<\/th>\n<th>\u03a3\u03c4\u03cc\u03c7\u03bf\u03c2<\/th>\n<th>\u039c\u03ad\u03b3\u03b9\u03c3\u03c4\u03bf<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Major depression (adult)<\/td>\n<td>25\u201350 mg HS<\/td>\n<td>100\u2013200 mg\/day<\/td>\n<td>300 mg<\/td>\n<\/tr>\n<tr>\n<td>Panic disorder<\/td>\n<td>10 mg OD \u00d7 1 wk<\/td>\n<td>50\u2013150 mg\/day<\/td>\n<td>200 mg<\/td>\n<\/tr>\n<tr>\n<td>Paediatric enuresis (\u22656 y)<\/td>\n<td>1.0\u20131.5 mg\/kg HS<\/td>\n<td>1.5\u20132.5 mg\/kg HS<\/td>\n<td>2.5 mg\/kg or 75 mg, whichever lower<\/td>\n<\/tr>\n<tr>\n<td>Older adults<\/td>\n<td>10 mg HS<\/td>\n<td>30\u201350 mg\/day<\/td>\n<td>by tolerability<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c3\u03c6\u03b1\u03bb\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03ba\u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Cardiac risk and overdose toxicity<\/strong><\/p>\n<p style=\"margin-bottom:0;\">TCAs prolong QRS and QT, and overdose is <strong>life-threatening<\/strong> \u2014 historically the most common cause of antidepressant fatalities. Baseline ECG before initiating in patients with known cardiac disease, on QT-prolonging therapy, or in older adults. Do not start in recent MI, conduction abnormality, uncompensated heart failure, or congenital long QT. Limit dispense quantities in patients at suicide risk \u2014 the therapeutic-to-toxic ratio is narrow.<\/p>\n<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>Anticholinergic burden<\/strong><\/p>\n<p style=\"margin-bottom:0;\">Dry mouth, constipation, blurred vision, urinary hesitancy, cognitive slowing \u2014 universal at therapeutic doses. Avoid in narrow-angle glaucoma, BPH with significant retention, and dementia. Pair with chewing gum \/ sugar-free lozenges, fibre + fluid, and stool softeners.<\/p>\n<\/div>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>\u039c\u03b1\u03cd\u03c1\u03bf \u03c0\u03bb\u03b1\u03af\u03c3\u03b9\u03bf \u03b1\u03c5\u03c4\u03bf\u03ba\u03c4\u03bf\u03bd\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 (\u03ba\u03ac\u03c4\u03c9 \u03c4\u03c9\u03bd 25)<\/strong><\/p>\n<p style=\"margin-bottom:0;\">All antidepressants carry an FDA black-box warning for increased suicidal ideation in patients under 25 \u2014 particularly relevant for clomipramine in adolescent OCD.<\/p>\n<\/div>\n<h2>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>Anticholinergic:<\/strong> dry mouth, constipation, blurred vision, urinary hesitancy.<\/li>\n<li><strong>Sedation:<\/strong> particularly doxepin and clomipramine; bedtime dosing helps.<\/li>\n<li><strong>\u039a\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac:<\/strong> orthostatic hypotension (\u03b11 block), tachycardia, conduction-interval prolongation.<\/li>\n<li><strong>\u039c\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac:<\/strong> weight gain (5\u201310 kg over 12 months in many patients), increased appetite.<\/li>\n<li><strong>Sexual:<\/strong> reduced libido, delayed ejaculation (sometimes used clinically for premature ejaculation), erectile difficulty.<\/li>\n<li><strong>Withdrawal:<\/strong> taper over 4 weeks; abrupt cessation produces flu-like symptoms, GI upset, and sleep disturbance.<\/li>\n<\/ul>\n<h2>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<ul>\n<li><strong>MAOIs<\/strong> \u2014 absolute contraindication. 14-day washout each direction.<\/li>\n<li><strong>SSRIs \/ SNRIs<\/strong> \u2014 additive serotonergic risk; CYP2D6 inhibition by fluoxetine and paroxetine raises TCA levels.<\/li>\n<li><strong>\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03bc\u03b7\u03ba\u03cd\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf QT<\/strong> (azoles, macrolides, amiodarone, sotalol, methadone, ondansetron, antipsychotics) \u2014 additive risk.<\/li>\n<li><strong>Other anticholinergics<\/strong> (oxybutynin, benztropine, antihistamines, clozapine, olanzapine) \u2014 additive burden in older adults.<\/li>\n<li><strong>CNS depressants<\/strong> \u2014 additive sedation.<\/li>\n<li><strong>Tramadol, bupropion, fluoroquinolones<\/strong> \u2014 lower seizure threshold; additive seizure risk.<\/li>\n<\/ul>\n<h2>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7, \u03b8\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2, \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae<\/h2>\n<p>TCAs are FDA pregnancy <strong>category C<\/strong>. Late-pregnancy exposure can produce neonatal anticholinergic withdrawal. Lactation: TCAs pass into breast milk in small amounts; nortriptyline and imipramine are the most-studied. Paediatric: imipramine is licensed from age 6 (enuresis) and clomipramine from age 10 (OCD); doxepin in adolescents only with specialist input.<\/p>\n<h2>\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>Store at 15\u201330 \u00b0C, away from direct sunlight, in original packaging. Keep out of reach of children \u2014 TCA paediatric ingestion is a medical emergency.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>How long until Antidep works?<\/h3>\n<p>TCAs typically show benefit within 2\u20134 weeks. The sleep and anxiety improvements often appear in week 1; the antidepressant effect builds over 4\u20136 weeks. <\/p>\n<h3>Why bedtime dosing?<\/h3>\n<p>Doxepin, clomipramine, and imipramine are all sedating. Bedtime dosing recruits the sedation as a side-effect benefit (sleep) instead of a side-effect burden (daytime drowsiness). It also reduces orthostatic hypotension by sleeping through the peak.<\/p>\n<h3>Is Antidep safe in older adults?<\/h3>\n<p>TCAs are on the Beers Criteria list of potentially inappropriate medications in older adults because of anticholinergic burden, orthostatic hypotension, and cardiac risk. They are not absolutely contraindicated but are generally second-line \u2014 SSRIs\/SNRIs are preferred unless a specific benefit (e.g. pain, sleep) outweighs the risks.<\/p>\n<h3>Can I drink alcohol on Antidep?<\/h3>\n<p>Alcohol amplifies TCA sedation and orthostatic effects. Limit to occasional and modest consumption; avoid binge drinking entirely. The combination is not usually dangerous in moderation but feels worse than either alone.<\/p>\n<h3>What is the overdose risk?<\/h3>\n<p>TCAs are among the most lethal classes of medication in overdose \u2014 <strong>cardiac conduction collapse, seizures, and coma<\/strong> can occur at relatively low multiples of the therapeutic dose. Limit dispense quantities in patients at any suicide risk. If overdose is suspected, present to emergency immediately \u2014 sodium bicarbonate is the antidote for the cardiac toxicity but timing matters.<\/p>\n<h3>Will Antidep affect my driving?<\/h3>\n<p>Sedation and reaction-time impairment are common in the first 1\u20132 weeks. Avoid driving until steady-state tolerability is known. Some patients tolerate full doses indefinitely without driving impairment; others remain too sedated even at low doses.<\/p>\n<h3>Can Antidep be combined with an SSRI?<\/h3>\n<p>Generally no \u2014 combination raises serotonin syndrome risk and serum TCA levels (particularly with fluoxetine and paroxetine). The combination is sometimes used in refractory OCD or depression under specialist supervision with TDM, never empirically.<\/p>\n<h3>How do I taper Antidep?<\/h3>\n<p>Reduce by approximately 25\u201350% of the dose every 2 weeks. Withdrawal (sometimes called &ldquo;TCA flu&rdquo;) produces malaise, GI upset, and sleep disturbance \u2014 manageable with slower tapers. Talk to the prescriber before stopping.<\/p>\n<h3>Does Antidep cause weight gain?<\/h3>\n<p>Yes \u2014 most TCAs cause meaningful weight gain over 6\u201312 months, often 5\u201310 kg. Doxepin and amitriptyline are the worst; nortriptyline less so. If this is a major concern, raise it before initiation \u2014 an SSRI\/SNRI may be a better fit.<\/p>\n<h3>Can Antidep be used for chronic pain?<\/h3>\n<p>Yes \u2014 TCAs (especially amitriptyline, nortriptyline, and imipramine) at low doses (10\u201375 mg) are first-line for diabetic peripheral neuropathy, post-herpetic neuralgia, and tension-type chronic headache. Sodium-channel blockade is the dominant mechanism. The analgesic effect is independent of the antidepressant effect and appears earlier (1\u20132 weeks).<\/p>\n<h2>\u0386\u03bb\u03bb\u03b1 \u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03a8\u03c5\u03c7\u03b9\u03ba\u03ae\u03c2 \u03a5\u03b3\u03b5\u03af\u03b1\u03c2<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/spectra\/\">Spectra (Doxepin TCA)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/doxin\/\">Doxin (Doxepin TCA)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/antidep\/\">Antidep (Imipramine TCA)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/flunil\/\">Flunil (Fluoxetine SSRI)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/duvanta\/\">Duvanta (Duloxetine SNRI)<\/a><\/li>\n<\/ul>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:0.9em;\">\n<strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd.<\/strong> \u0391\u03c5\u03c4\u03ae \u03b7 \u03c3\u03b5\u03bb\u03af\u03b4\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03ae\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c4\u03bf \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae\u03c2. \u0397 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c8\u03c5\u03c7\u03b9\u03ba\u03ae\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03be\u03b5\u03ba\u03b9\u03bd\u03ac, \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03cc\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c5\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b2\u03bb\u03b5\u03c8\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03ba\u03b1\u03c4\u03b1\u03be\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd. \u0395\u03ac\u03bd \u03b5\u03c3\u03b5\u03af\u03c2 \u03ae \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03c4\u03b5 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03c1\u03af\u03c3\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ba\u03c4\u03bf\u03bd\u03af\u03b1\u03c2, \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03ae\u03c3\u03c4\u03b5 \u03b1\u03bc\u03ad\u03c3\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03c4\u03bf\u03c0\u03b9\u03ba\u03ad\u03c2 \u03c5\u03c0\u03b7\u03c1\u03b5\u03c3\u03af\u03b5\u03c2 \u03ad\u03ba\u03c4\u03b1\u03ba\u03c4\u03b7\u03c2 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7\u03c2 \u03ae \u03ba\u03b1\u03bb\u03ad\u03c3\u03c4\u03b5 \u03c4\u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ba\u03c4\u03bf\u03bd\u03b9\u03ce\u03bd \u03c4\u03b7\u03c2 \u03c7\u03ce\u03c1\u03b1\u03c2 \u03c3\u03b1\u03c2 (\u0397\u03a0\u0391\/\u039a\u03b1\u03bd\u03b1\u03b4\u03ac\u03c2: 988; \u0397\u0392: Samaritans 116 123; \u03b4\u03b9\u03b5\u03b8\u03bd\u03ae\u03c2 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2: <a href=\"https:\/\/findahelpline.com\/\" rel=\"nofollow noopener\" target=\"_blank\">findahelpline.com<\/a>).\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Antidep (Imipramine 25\/75 mg) \u2014 first-generation TCA for depression, panic, paediatric enuresis \u22656 y. reference TCA \u2014 balanced 5-HT\/NA reuptake blockade.<\/p>","protected":false},"featured_media":57636,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3906],"product_tag":[4339,4333],"class_list":{"0":"post-57635","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-mental-health-and-psychiatric-medications","9":"product_tag-antidep","10":"product_tag-imipramine","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/57635","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=57635"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/57636"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=57635"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=57635"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=57635"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=57635"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}