{"id":57812,"date":"2024-02-27T18:02:03","date_gmt":"2024-02-27T18:02:03","guid":{"rendered":"https:\/\/medsname.com\/ivrea-cream\/"},"modified":"2026-05-11T14:13:26","modified_gmt":"2026-05-11T14:13:26","slug":"ivrea-cream","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/ivrea-cream\/","title":{"rendered":"Ivrea Cream"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Ivrea Cream?<\/h3>\n<p style=\"margin:0;\"><strong>Ivrea Cream<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>topical 1% ivermectin<\/strong> preparation in a 30&nbsp;g tube. Its FDA-licensed use is <strong>papulopustular (inflammatory) rosacea<\/strong>, where it reduces the inflammation and redness driven by <em>Demodex folliculorum<\/em> skin mites. It is also used <strong>off-label for head lice and small-area scabies<\/strong> in some regions. Apply a pea-sized amount once daily to affected areas of clean, dry skin for up to 16 weeks. Generic equivalent of Galderma&#8217;s <strong>Soolantra<sup>\u00ae<\/sup><\/strong>.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:6px;font-size:0.95em;\">\n<strong>\ud83c\udfed WHO-GMP certified manufacturer<\/strong> \u00b7 <strong>\ud83d\udce6 Discreet packaging<\/strong> (plain envelope) &middot; <strong>\ud83c\udf0d Worldwide shipping<\/strong> \u03bc\u03b5 <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance<\/strong><\/a> \u00b7 <strong>\u2b50 1,400+ customers<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<p><strong>Ivrea Cream<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>topical ivermectin 1% w\/w cream<\/strong> supplied in a 30&nbsp;g tube. It is designed for <strong>once-daily application to the face<\/strong> to treat the inflammatory papules and pustules of <strong>rosacea<\/strong>, and is also used off-label for certain ectoparasite conditions.<\/p>\n<p>Ivrea Cream contains the same active ingredient and strength as Galderma&#8217;s branded <strong>Soolantra<sup>\u00ae<\/sup><\/strong> &mdash; a first-line topical therapy in current dermatology guidelines for papulopustular rosacea. By combining an <strong>antiparasitic<\/strong> \u03ba\u03b1\u03b9 <strong>anti-inflammatory<\/strong> action on the skin&#8217;s surface, 1% ivermectin directly addresses the two mechanisms believed to drive rosacea-related lesions.<\/p>\n<h2 class=\"wp-block-heading\">What Is Ivrea Cream?<\/h2>\n<p>Ivrea Cream delivers <strong>ivermectin 1%<\/strong> in a moisturising cream base suitable for the face. Topical ivermectin at this concentration has two relevant effects on the skin:<\/p>\n<ul>\n<li><strong>Anti-parasitic<\/strong> &mdash; kills <em>Demodex folliculorum<\/em> mites that live in hair follicles, whose over-population is strongly associated with rosacea flares<\/li>\n<li><strong>\u0391\u03bd\u03c4\u03b9\u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03b5\u03c2<\/strong> &mdash; directly modulates local inflammatory pathways in the skin, reducing the visible redness and papule formation independently of its mite-killing effect<\/li>\n<\/ul>\n<p>Ivrea Cream is used for:<\/p>\n<ul>\n<li><strong>Papulopustular rosacea<\/strong> (inflammatory rosacea) &mdash; the primary and licensed indication<\/li>\n<li><strong>Demodex-associated facial dermatitis \/ demodicosis<\/strong> &mdash; where mite over-population drives itching, redness, or blepharitis<\/li>\n<li><strong>Off-label head lice (pediculosis capitis)<\/strong> &mdash; a single 10-minute application to dry hair and scalp<\/li>\n<li><strong>Off-label small-area scabies<\/strong> &mdash; oral ivermectin or 5% permethrin cream is usually preferred for whole-body treatment; topical 1% ivermectin may be used in limited lesions or adjunctively<\/li>\n<\/ul>\n<p><strong>Ivrea Cream is not the same as high-strength scabies creams.<\/strong> For widespread scabies infestation, <strong>permethrin 5%<\/strong> or oral ivermectin (e.g. <a href=\"https:\/\/medsbase.com\/el\/iverjohn\/\" rel=\"noopener\">Iverjohn<\/a>, <a href=\"https:\/\/medsbase.com\/el\/iverheal\/\" rel=\"noopener\">Iverheal<\/a>) remain first-line.<\/p>\n<h2 class=\"wp-block-heading\">How Does Ivrea Cream Work?<\/h2>\n<p>Ivermectin is a <strong>macrocyclic lactone<\/strong> derived originally from the soil bacterium <em>Streptomyces avermitilis<\/em>. Applied topically at 1%:<\/p>\n<ul>\n<li>It selectively binds <strong>glutamate-gated chloride channels<\/strong> in arthropod and nematode nerve cells, causing hyperpolarisation, paralysis, and death of the target organism<\/li>\n<li>In rosacea skin, it <strong>kills Demodex mites<\/strong> resident in the sebaceous ducts &mdash; reducing the inflammatory stimulus the mites create<\/li>\n<li>Independently, ivermectin has a <strong>direct anti-inflammatory effect<\/strong>: it suppresses LPS-induced inflammatory cytokine production, down-regulates toll-like receptor signalling, and reduces neutrophil activity in the skin<\/li>\n<li>Clinical response typically becomes visible within <strong>4 weeks<\/strong> and peaks by <strong>12\u201316 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong><\/li>\n<\/ul>\n<p>In head lice, a single application is enough to paralyse both adult lice and newly-hatched nymphs &mdash; the cream remains in the hair long enough to kill the nymphs that emerge after treatment.<\/p>\n<h2 class=\"wp-block-heading\">\u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Papulopustular rosacea<\/strong> &mdash; first-line topical, included in global dermatology guidelines (AAD, BAD, German S2k)<\/li>\n<li><strong>Ocular rosacea with blepharitis<\/strong> &mdash; off-label adjunct<\/li>\n<li><strong>Demodex folliculorum overgrowth<\/strong> &mdash; facial or eyelid-margin infestation<\/li>\n<li><strong>Head lice (pediculosis capitis)<\/strong> &mdash; single application to scalp and hair<\/li>\n<li><strong>Localised scabies lesions<\/strong> &mdash; off-label, usually alongside oral or whole-body topical therapy<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Ivrea Cream Dosage and Administration<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th>Amount<\/th>\n<th>Frequency \/ Duration<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Papulopustular rosacea<\/strong><\/td>\n<td>Pea-sized amount per affected area (~5 small dots spread over the face)<\/td>\n<td>Once daily for up to 16 weeks; can repeat 16-week courses<\/td>\n<\/tr>\n<tr>\n<td><strong>Ocular rosacea \/ blepharitis<\/strong><\/td>\n<td>Thin layer applied to eyelid margin (avoid eye)<\/td>\n<td>Once daily for 4&ndash;8 weeks under ophthalmological supervision<\/td>\n<\/tr>\n<tr>\n<td><strong>Head lice<\/strong><\/td>\n<td>Enough to thoroughly coat dry hair and scalp<\/td>\n<td>Single application left in place for 10 minutes, then rinse; repeat in 7&ndash;10 days if needed<\/td>\n<\/tr>\n<tr>\n<td><strong>Localised scabies (adjunct)<\/strong><\/td>\n<td>Thin layer to affected area<\/td>\n<td>Once daily for 7 days &mdash; usually combined with oral ivermectin or permethrin<\/td>\n<\/tr>\n<tr>\n<td><strong>Children<\/strong><\/td>\n<td>Not routinely recommended under 18<\/td>\n<td>Off-label paediatric use under dermatology guidance<\/td>\n<\/tr>\n<tr>\n<td><strong>Elderly<\/strong><\/td>\n<td>\u03a4\u03c5\u03c0\u03b9\u03ba\u03ae \u03b4\u03cc\u03c3\u03b7<\/td>\n<td>No adjustment needed<\/td>\n<\/tr>\n<tr>\n<td><strong>\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/strong><\/td>\n<td>Caution<\/td>\n<td>Systemic absorption of topical ivermectin is minimal, so clinical risk is low<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"wp-block-heading\">How to Apply Ivrea Cream Properly<\/h3>\n<ul>\n<li><strong>Clean<\/strong> the affected skin with a mild, soap-free cleanser and pat dry. Do not apply to wet skin<\/li>\n<li>Dispense a <strong>pea-sized amount<\/strong> and divide it into 5 small dots across forehead, cheeks, chin, and nose<\/li>\n<li>Spread a thin, even layer &mdash; rub in gently until the cream disappears. Do not pile it on<\/li>\n<li>Avoid the <strong>eyes, lips, and mucous membranes<\/strong><\/li>\n<li>Wash hands after application<\/li>\n<li>Allow several minutes to absorb before applying moisturisers, sunscreen, or makeup over it<\/li>\n<li>Continue nightly even if initial response is subtle &mdash; most benefit builds between weeks 4 and 16<\/li>\n<li>Do not combine with other topical rosacea treatments (e.g. metronidazole, azelaic acid) on the same day without medical advice<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Side Effects of Ivrea Cream<\/h2>\n<p>Topical ivermectin is very well tolerated &mdash; systemic absorption is minimal so systemic side effects are rare.<\/p>\n<table>\n<thead>\n<tr>\n<th>\u0392\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1<\/th>\n<th>\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 (\u22651 \u03c3\u03c4\u03bf\u03c5\u03c2 100)<\/strong><\/td>\n<td>Mild burning or stinging on application, dry skin, mild transient itching<\/td>\n<\/tr>\n<tr>\n<td><strong>\u0391\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03b5\u03c2<\/strong><\/td>\n<td>Skin irritation, contact dermatitis, worsening rosacea during the first 1&ndash;2 weeks (&#8220;initial flare&#8221;)<\/td>\n<\/tr>\n<tr>\n<td><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b5\u03c2<\/strong><\/td>\n<td>Allergic contact dermatitis, urticaria, photosensitivity<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Initial flare:<\/strong> some patients see a transient worsening of rosacea in the first 1&ndash;2 weeks as dying Demodex mites release inflammatory contents &mdash; this usually settles and is not a reason to stop treatment. If discomfort is marked, reduce to alternate-day application for the first 2 weeks and resume daily dosing afterward.<\/p>\n<h2 class=\"wp-block-heading\">\u03a0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03ac\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Avoid eye contact.<\/strong> If accidental contact occurs, rinse with plenty of water<\/li>\n<li><strong>Do not swallow.<\/strong> Oral ingestion of topical ivermectin is unlikely to cause serious harm at the quantities in a 30&nbsp;g tube, but seek medical advice if ingestion is significant<\/li>\n<li><strong>Pregnancy.<\/strong> Limited human data &mdash; use only if the potential benefit justifies the risk. Topical absorption is minimal<\/li>\n<li><strong>Breastfeeding.<\/strong> Small amounts of oral ivermectin pass into breast milk; topical exposure is expected to be far lower. Avoid applying to the breast area while breastfeeding<\/li>\n<li><strong>Children under 18.<\/strong> Not routinely recommended &mdash; paediatric use only under dermatology supervision<\/li>\n<li><strong>Sun exposure.<\/strong> Rosacea is worsened by UV &mdash; daily broad-spectrum sunscreen (SPF 30+) alongside Ivrea Cream improves long-term outcomes<\/li>\n<li><strong>Triggers.<\/strong> Continue avoiding rosacea triggers (alcohol, spicy food, temperature extremes, harsh skincare)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications &mdash; Who Should NOT Use Ivrea Cream<\/h2>\n<ul>\n<li>Known hypersensitivity to ivermectin or any excipient<\/li>\n<li>Application to broken, weeping, or severely inflamed skin where another dermatitis is present<\/li>\n<li>Application to mucous membranes or directly into the eye<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<p>Topical ivermectin has minimal systemic absorption, so clinically significant drug interactions are rare.<\/p>\n<table>\n<thead>\n<tr>\n<th>Agent<\/th>\n<th>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Other topical rosacea therapies (metronidazole gel, azelaic acid, brimonidine)<\/strong><\/td>\n<td>Do not apply at the same time of day; separate by 12 hours or alternate days<\/td>\n<\/tr>\n<tr>\n<td><strong>Retinoids (tretinoin, adapalene, tazarotene)<\/strong><\/td>\n<td>Can be combined if skin tolerates; start on alternate days and build up<\/td>\n<\/tr>\n<tr>\n<td><strong>Cosmetics and sunscreens<\/strong><\/td>\n<td>Apply after Ivrea Cream has absorbed &mdash; allow 5&ndash;10 minutes<\/td>\n<\/tr>\n<tr>\n<td><strong>Corticosteroid creams<\/strong><\/td>\n<td>Do not apply alongside topical steroids; they can trigger rebound rosacea<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Tell your doctor about all skincare products you use, including over-the-counter cleansers, exfoliants, and acid treatments &mdash; these can irritate rosacea-prone skin.<\/p>\n<h2 class=\"wp-block-heading\">\u03a4\u03b9 \u03bd\u03b1 \u039a\u03ac\u03bd\u03b5\u03c4\u03b5 \u03c3\u03b5 \u03a0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03a5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2<\/h2>\n<p>Accidental swallowing of a small amount is unlikely to cause significant toxicity because topical formulations contain dilute active ingredient. In case of large-volume ingestion, contact your local poisons service or emergency department. Skin over-application can cause increased local irritation but not systemic toxicity.<\/p>\n<h2 class=\"wp-block-heading\">\u039f\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2<\/h2>\n<ul>\n<li>\u0391\u03c0\u03bf\u03b8\u03b7\u03ba\u03b5\u03cd\u03c3\u03c4\u03b5 \u03c3\u03b5 \u03b8\u03b5\u03c1\u03bc\u03bf\u03ba\u03c1\u03b1\u03c3\u03af\u03b1 \u03ba\u03ac\u03c4\u03c9 \u03b1\u03c0\u03cc 30\u00b0C \u03c3\u03b5 \u03be\u03b7\u03c1\u03cc \u03bc\u03ad\u03c1\u03bf\u03c2, \u03bc\u03b1\u03ba\u03c1\u03b9\u03ac \u03b1\u03c0\u03cc \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b7\u03bb\u03b9\u03b1\u03ba\u03ae \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b2\u03bf\u03bb\u03af\u03b1<\/li>\n<li>Do not freeze<\/li>\n<li>Recap the tube tightly after use<\/li>\n<li>Discard 6 months after first opening even if product remains<\/li>\n<li>\u039a\u03c1\u03b1\u03c4\u03ae\u03c3\u03c4\u03b5 \u03bc\u03b1\u03ba\u03c1\u03b9\u03ac \u03b1\u03c0\u03cc \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03bf\u03b9\u03ba\u03af\u03b4\u03b9\u03b1<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u039b\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf MedsBase<\/h2>\n<p>Looking for related rosacea, Demodex, or parasite-treatment options?<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/metrogyl\/\" rel=\"noopener\">Metrogyl<\/a> &mdash; metronidazole, an alternative topical rosacea treatment<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/iverjohn\/\" rel=\"noopener\">Iverjohn<\/a> &mdash; oral ivermectin tablets for scabies and widespread demodicosis<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/iverheal\/\" rel=\"noopener\">Iverheal<\/a> &mdash; alternative oral ivermectin tablet brand<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/ivermectol\/\" rel=\"noopener\">Ivermectol<\/a> &mdash; Sun Pharma oral ivermectin<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/lice-scabies-treatment\/\" rel=\"noopener\">Browse all Lice &amp; Scabies treatments &rarr;<\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">What is Ivrea Cream used for?<\/h3>\n<p>Ivrea Cream is a topical <strong>1% ivermectin<\/strong> preparation. Its primary licensed indication is <strong>papulopustular rosacea<\/strong>, where it reduces inflammatory papules, pustules, and redness. It is also used off-label for head lice and localised scabies lesions.<\/p>\n<h3 class=\"wp-block-heading\">How fast does Ivrea Cream work?<\/h3>\n<p>For rosacea, early improvement usually appears by <strong>4 weeks<\/strong>, with peak effect at <strong>12\u201316 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong>. A transient &#8220;initial flare&#8221; in the first 1&ndash;2 weeks is common as Demodex mites die off &mdash; persist through this.<\/p>\n<h3 class=\"wp-block-heading\">Is Ivrea Cream the same as Soolantra?<\/h3>\n<p>Yes in active ingredients and strength &mdash; both contain 1% ivermectin. Ivrea Cream is the generic equivalent of Galderma&#8217;s branded Soolantra<sup>\u00ae<\/sup>, at a fraction of the price.<\/p>\n<h3 class=\"wp-block-heading\">Can Ivrea Cream treat scabies?<\/h3>\n<p>It can help with <strong>small, localised scabies lesions<\/strong>, but it is not the first-line therapy for widespread scabies. For whole-body scabies, <strong>permethrin 5% cream<\/strong> \u03ae <strong>oral ivermectin tablets<\/strong> (e.g. <a href=\"https:\/\/medsbase.com\/el\/iverjohn\/\" rel=\"noopener\">Iverjohn<\/a>) are standard. Always treat household contacts at the same time and decontaminate bedding and clothing.<\/p>\n<h3 class=\"wp-block-heading\">How much should I apply?<\/h3>\n<p>A <strong>pea-sized amount<\/strong> for the whole face. More is not better &mdash; excess cream increases irritation without improving response.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Ivrea Cream with other rosacea treatments?<\/h3>\n<p>Yes, but not at the same time. Many patients use Ivrea Cream at night and a different agent (e.g. brimonidine gel for redness, or azelaic acid) in the morning. Do <strong>\u03b4\u03b5\u03bd<\/strong> combine with topical steroids &mdash; they trigger rebound rosacea.<\/p>\n<h3 class=\"wp-block-heading\">Do I still need to avoid rosacea triggers?<\/h3>\n<p>Yes. Topical ivermectin treats inflammation but does not change underlying skin vascular reactivity. Continue to avoid triggers (alcohol, spicy food, hot drinks, heat, harsh cleansers) and use daily broad-spectrum sunscreen.<\/p>\n<h3 class=\"wp-block-heading\">Is Ivrea Cream safe during pregnancy?<\/h3>\n<p>Topical absorption is minimal, but safety data in pregnancy is limited. Use only if clearly needed and discuss with your doctor. Avoid during breastfeeding on the breast area.<\/p>\n<h3 class=\"wp-block-heading\">How long can I use Ivrea Cream?<\/h3>\n<p>Licensed treatment courses are up to <strong>16 weeks<\/strong>. Repeat courses are common in rosacea, which is a chronic condition. Many patients use it long-term at reduced frequency (e.g. 2&ndash;3 nights weekly) as maintenance, under dermatology guidance.<\/p>\n<h3 class=\"wp-block-heading\">Can I use Ivrea Cream for acne?<\/h3>\n<p>It is not licensed for acne vulgaris, which is a different condition driven by <em>Cutibacterium acnes<\/em> (\u03c0\u03b1\u03bb\u03b1\u03b9\u03cc\u03c4\u03b5\u03c1\u03b1 <em>P. acnes<\/em>) rather than Demodex. If you have overlapping acne and rosacea, discuss a combined approach with a dermatologist.<\/p>\n<h3 class=\"wp-block-heading\">What if my skin stings the first time?<\/h3>\n<p>Mild burning or stinging in the first few applications is common and usually settles. If strong or persistent, reduce to alternate-day application for 1&ndash;2 weeks, use a gentle moisturiser underneath, and rebuild tolerance. Stop if a true contact dermatitis develops (widespread rash, severe burning).<\/p>\n<p><!-- medsbase-faq-h3-converted --><\/p>\n<h3 class=\"wp-block-heading\">\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Choosing Ivrea Cream from MedsBase gives you:<\/p>\n<ul>\n<li><strong>WHO-GMP certified<\/strong> \u2014 sourced from inspected manufacturing facilities<\/li>\n<li><strong>\u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/strong> \u2014 plain envelope, no medication name or pharmacy branding visible<\/li>\n<li><strong>\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/strong> \u03bc\u03b5 <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance<\/a> \u2014 every order covered<\/li>\n<li><strong>\u0395\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/strong> \u2014 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">1,400+ reviews<\/a> across the catalogue<\/li>\n<li><strong>Multiple payment options<\/strong> \u2014 including a 10% discount when you pay with cryptocurrency<\/li>\n<\/ul>\n<p class=\"medsbase-link-boost-2026-05-11\" data-marker=\"mb-link-boost-ivrea-shampoo\">Patients already using <a href=\"https:\/\/medsbase.com\/el\/ivrea-cream\/\">Ivrea Cream (ivermectin 1% topical cream)<\/a> for papulopustular rosacea who develop concurrent scalp pediculosis can stay within the same ivermectin platform by adding <a href=\"https:\/\/medsbase.com\/el\/ivrea-shampoo\/\">Ivrea Shampoo (ivermectin 1% shampoo)<\/a>, avoiding the need to introduce a chemically unrelated pediculicide.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 <strong>\u0393\u03b5\u03bd\u03b9\u03ba\u03ae \u03a5\u03b3\u03b5\u03af\u03b1<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/obsenil\/\">Obsenil<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/vermact\/\">Vermact<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/roko\/\">Roko<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tetrafol\/\">Tetrafol<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/permiforce-cream\/\">Permiforce Cream<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Treats skin parasites<br \/>\n\u2705 Topical application<br \/>\n\u2705 Eliminates mites<br \/>\n\u2705 Relieves scabies symptoms<br \/>\n\u2705 Soothes itching<\/p>\n<p><strong>Ivrea Cream<\/strong> \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 <strong>\u0399\u03b2\u03b5\u03c1\u03bc\u03b5\u03ba\u03c4\u03af\u03bd\u03b7<\/strong>.<\/p>","protected":false},"featured_media":57813,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3563,3141,3342,3579],"product_tag":[5690,5691,5686,4363,5689,5688,5692,5687,5685],"class_list":{"0":"post-57812","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-rosacea-treatment","7":"product_cat-category-overview","8":"product_cat-general-health","9":"product_cat-lice-scabies-treatment","10":"product_tag-demodex","11":"product_tag-head-lice","12":"product_tag-ivermectin-cream","13":"product_tag-ivrea-cream","14":"product_tag-papulopustular-rosacea","15":"product_tag-rosacea-treatment","16":"product_tag-scabies","17":"product_tag-soolantra-generic","18":"product_tag-topical-ivermectin","20":"first","21":"instock","22":"shipping-taxable","23":"purchasable","24":"product-type-variable","25":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/57812","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=57812"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/57813"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=57812"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=57812"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=57812"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=57812"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}