<\/p>\n
Trajenta Duo<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03b9 linagliptin (2.5 mg)<\/strong> \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03c6\u03bf\u03c1\u03bc\u03af\u03bd\u03b7 (500 mg \u03ae 1000 mg)<\/strong> \u03b3\u03b9\u03b1 \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03c4\u03cd\u03c0\u03bf\u03c5 2<\/strong>. It pairs complementary mechanisms: metformin reduces hepatic glucose production and improves insulin sensitivity, while linagliptin (a DPP-4 inhibitor) raises incretin hormones to stimulate glucose-dependent insulin release and suppress glucagon. Expected HbA1c reduction: 1,5\u20132,0 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2<\/strong>. \u039f\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03bf \u03c9\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2<\/strong> and very low hypoglycaemia risk as a combination. Usual dose: one tablet twice daily with meals. Main side effects are metformin GI upset in the first 1–2 weeks. The linagliptin component needs no renal dose adjustment; the metformin component follows standard rules — avoid if eGFR < 30. Avoid in type 1 diabetes, DKA, eGFR < 30, and severe hepatic impairment.<\/p>\n<\/div>\n \ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n \u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n Trajenta Duo is a fixed-dose combination oral antidiabetic tablet containing linagliptin (2.5 mg)<\/strong> \u03ba\u03b1\u03b9 \u03c5\u03b4\u03c1\u03bf\u03c7\u03bb\u03c9\u03c1\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03c6\u03bf\u03c1\u03bc\u03af\u03bd\u03b7 (500 mg \u03ae 1000 mg)<\/strong>, manufactured by Boehringer Ingelheim. Available in packs of 30, 60, 90 or 180 tablets. It is used when monotherapy with either component is not enough, or as initial combination therapy when HbA1c is substantially above target.<\/p>\n Trajenta Duo combines two complementary mechanisms that do not overlap:<\/p>\n \u0395\u03c0\u03b5\u03b9\u03b4\u03ae \u03ba\u03b1\u03bd\u03ad\u03bd\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b1 \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ac \u03b4\u03b5\u03bd \u03b4\u03b9\u03b5\u03b3\u03b5\u03af\u03c1\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03c3\u03b7 \u03b9\u03bd\u03c3\u03bf\u03c5\u03bb\u03af\u03bd\u03b7\u03c2 \u03b1\u03bd\u03b5\u03be\u03ac\u03c1\u03c4\u03b7\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7 \u03c4\u03bf\u03c5 \u03b1\u03af\u03bc\u03b1\u03c4\u03bf\u03c2, \u03bf \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03ad\u03c7\u03b5\u03b9 \u03c0\u03bf\u03bb\u03cd \u03c7\u03b1\u03bc\u03b7\u03bb\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03c5\u03c0\u03bf\u03b3\u03bb\u03c5\u03ba\u03b1\u03b9\u03bc\u03af\u03b1\u03c2. \u03a4\u03c5\u03c0\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 HbA1c: 1,5\u20132,0 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03b9\u03b1\u03af\u03b5\u03c2 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2<\/strong>. \u0395\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2: \u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03b7 \u03ae \u03b5\u03bb\u03b1\u03c6\u03c1\u03ce\u03c2 \u03b1\u03b4\u03c5\u03bd\u03b1\u03c4\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae (\u03b1\u03c0\u03cc \u03c4\u03b7 \u03bc\u03b5\u03c4\u03c6\u03bf\u03c1\u03bc\u03af\u03bd\u03b7).<\/p>\n \u03a3\u03c5\u03bd\u03ae\u03b8\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7:<\/strong> \u03ad\u03bd\u03b1 \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03b4\u03cd\u03bf \u03c6\u03bf\u03c1\u03ad\u03c2 \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1, \u03bc\u03b5 \u03c0\u03c1\u03c9\u03b9\u03bd\u03cc \u03ba\u03b1\u03b9 \u03b4\u03b5\u03af\u03c0\u03bd\u03bf. \u0397 \u03b4\u03cc\u03c3\u03b7 \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03cd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03c4\u03bf\u03bd \u03c3\u03c4\u03cc\u03c7\u03bf HbA1c \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1.<\/p>\n \u0391\u03c0\u03cc \u03c4\u03b7 \u03bc\u03b5\u03c4\u03c6\u03bf\u03c1\u03bc\u03af\u03bd\u03b7 (\u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c4\u03b9\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b5\u03c2 1\u20132 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2):<\/strong><\/p>\n \u0391\u03c0\u03cc \u03c4\u03bf\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ad\u03b1 DPP-4:<\/strong><\/p>\n \u03a3\u03c0\u03ac\u03bd\u03b9\u03bf \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03cc:<\/strong><\/p>\n Store Trajenta Duo below 30°C in a dry place, in the original blister pack. Keep out of reach of children.<\/p>\n \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac, \u03bd\u03b1\u03b9 \u2014 \u03af\u03b4\u03b9\u03b1 \u03bc\u03cc\u03c1\u03b9\u03b1 \u03c3\u03c4\u03b9\u03c2 \u03af\u03b4\u03b9\u03b5\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2. \u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03bc\u03bc\u03cc\u03c1\u03c6\u03c9\u03c3\u03b7, \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf \u03c6\u03bf\u03c1\u03c4\u03af\u03bf \u03c7\u03ac\u03c0\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03ba\u03bf\u03c3\u03c4\u03af\u03b6\u03b5\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03cc \u03c4\u03b1 \u03b4\u03cd\u03bf \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ac \u03c0\u03bf\u03c5 \u03b1\u03b3\u03bf\u03c1\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c7\u03c9\u03c1\u03b9\u03c3\u03c4\u03ac. \u03a4\u03bf \u03bc\u03b5\u03b9\u03bf\u03bd\u03ad\u03ba\u03c4\u03b7\u03bc\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7 \u03b5\u03c5\u03b5\u03bb\u03b9\u03be\u03af\u03b1 \u03c3\u03c4\u03b7 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1.<\/p>\n On its own, very rarely. Neither DPP-4 inhibitors nor metformin stimulates insulin release independent of glucose. Hypoglycaemia becomes a concern only when Trajenta Duo is combined with a sulfonylurea, meglitinide, or insulin.<\/p>\n \u038c\u03c7\u03b9. \u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03bf\u03c2 \u03c9\u03c2 \u03c0\u03c1\u03bf\u03c2 \u03c4\u03bf \u03b2\u03ac\u03c1\u03bf\u03c2 \u03ae \u03b5\u03bb\u03b1\u03c6\u03c1\u03ce\u03c2 \u03b1\u03b4\u03c5\u03bd\u03b1\u03c4\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc\u03c2, \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03c0\u03bf\u03c5 \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1\u03c2 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc\u03c2 \u03bb\u03cc\u03b3\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c4\u03b9\u03bc\u03ac\u03c4\u03b1\u03b9 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03ce\u03bd \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03b9\u03c2 \u03c3\u03bf\u03c5\u03bb\u03c6\u03bf\u03bd\u03c5\u03bb\u03bf\u03c5\u03c1\u03af\u03b5\u03c2 \u03c3\u03b5 \u03c5\u03c0\u03ad\u03c1\u03b2\u03b1\u03c1\u03b1 \u03ac\u03c4\u03bf\u03bc\u03b1.<\/p>\n \u0397 \u03b3\u03bb\u03c5\u03ba\u03cc\u03b6\u03b7 \u03bd\u03b7\u03c3\u03c4\u03b5\u03af\u03b1\u03c2 \u03b1\u03c1\u03c7\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03ad\u03c6\u03c4\u03b5\u03b9 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1. \u0397 \u03bc\u03ad\u03b3\u03b9\u03c3\u03c4\u03b7 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd HbA1c \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03b5\u03af\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b9\u03c2 12 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2. \u0395\u03ac\u03bd \u03b7 HbA1c \u03b4\u03b5\u03bd \u03ad\u03c7\u03b5\u03b9 \u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd \u03ba\u03b1\u03c4\u03ac 0,5% \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc 3 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03c3\u03c4\u03b7 \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b4\u03cc\u03c3\u03b7, \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af\u03c4\u03b1\u03b9 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1.<\/p>\n \u0397 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03ba\u03b1\u03c4\u03b1\u03bd\u03ac\u03bb\u03c9\u03c3\u03b7 \u03b1\u03bb\u03ba\u03bf\u03cc\u03bb \u03bc\u03b5 \u03c6\u03b1\u03b3\u03b7\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c3\u03c6\u03b1\u03bb\u03ae\u03c2. \u0391\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5 \u03c4\u03b7\u03bd \u03c5\u03c0\u03b5\u03c1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03b1\u03bd\u03ac\u03bb\u03c9\u03c3\u03b7 \u2014 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae\u03c2 \u03bf\u03be\u03ad\u03c9\u03c3\u03b7\u03c2 (\u03bc\u03b5\u03c4\u03c6\u03bf\u03c1\u03bc\u03af\u03bd\u03b7) \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03ae\u03c0\u03b1\u03c4\u03bf\u03c2.<\/p>\n You can order Trajenta Duo (Linagliptin 2.5 mg + Metformin 500\/1000 mg (twice daily)) from MedsBase in packs of 30, 60, 90 or 180 tablets. We ship worldwide, with discreet packaging and genuine WHO-GMP certified manufacturer stock.<\/p>\n Patients discontinuing the linagliptin component of Trajenta Duo<\/a> while continuing metformin may transition directly to Glycomet SR (metformin hydrochloride 500\u20131000 mg SR)<\/a>, available in the same 500 mg and 1000 mg SR strengths as the original combination tablet.<\/p>\n <\/p>\n \u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 \u03a7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n \u2705 Dual-action control Trajenta Duo contains Linagliptin & Metformin.<\/p>","protected":false},"featured_media":58206,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3230,3231],"product_tag":[3278,3255,4443],"class_list":{"0":"post-58205","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-diabetes","9":"product_cat-diabetes-medication","10":"product_tag-linagliptin","11":"product_tag-metformin","12":"product_tag-trajenta-duo","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/58205","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=58205"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/58206"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=58205"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=58205"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=58205"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=58205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n
What Is Trajenta Duo?<\/h2>\n
How Does Trajenta Duo Work?<\/h2>\n
\n
\u0394\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03a7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7<\/h2>\n
\n
\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n
\n
\n
\n
\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n
\n
Who Should Not Take Trajenta Duo?<\/h2>\n
\n
\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n
\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n
Is Trajenta Duo the same as taking Trajenta and metformin separately?<\/h3>\n
Will Trajenta Duo cause hypoglycaemia?<\/h3>\n
Will I gain weight on Trajenta Duo?<\/h3>\n
How long before Trajenta Duo starts working?<\/h3>\n
Can I drink alcohol while taking Trajenta Duo?<\/h3>\n
Where can I buy Trajenta Duo online?<\/h3>\n
\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03b3\u03b9\u03b1 \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7<\/h2>\n
\n
\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n
\n
\n\u2705 Regulates blood sugar
\n\u2705 Combines two medications
\n\u2705 \u0392\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b9\u03bd\u03c3\u03bf\u03c5\u03bb\u03af\u03bd\u03b7
\n\u2705 Manages type 2 diabetes<\/p>\n