{"id":59468,"date":"2024-02-28T05:59:35","date_gmt":"2024-02-28T05:59:35","guid":{"rendered":"https:\/\/medsname.com\/terbijohn\/"},"modified":"2026-04-30T10:23:57","modified_gmt":"2026-04-30T10:23:57","slug":"terbijohn","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/terbijohn\/","title":{"rendered":"Terbijohn"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 20px;margin:18px 0;border-radius:6px;\">\n<h3 style=\"margin-top:0;\">\ud83d\udca1 \u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u0391\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7<\/h3>\n<p style=\"margin-bottom:0;\">Terbijohn is terbinafine 250 mg oral tablet \u2014 an allylamine antifungal and the <strong>first-line oral treatment for dermatophyte onychomycosis (toenail \/ fingernail fungus) and tinea capitis<\/strong>. 250 mg once daily \u00d7 6 weeks (fingernails) or 12 weeks (toenails). Concentrates in skin and nails \u2014 persists in the nail bed for weeks after the last dose. Best cure rates of any oral antifungal for dermatophyte infections (~76%). LFT monitoring required; rare but serious hepatotoxicity. Not effective against Candida or non-dermatophyte yeasts \u2014 confirm dermatophyte before starting.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f5f5;border:1px solid #e1e1e1;padding:18px 22px;margin:24px 0;border-radius:8px;display:flex;flex-wrap:wrap;justify-content:space-around;gap:16px;align-items:center;font-size:0.95em;\">\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udfed<br \/><strong>WHO-GMP<\/strong><br \/>certified manufacturer<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83d\udce6<br \/><strong>\u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/strong><br \/>plain envelope<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udf0d<br \/><strong>\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/strong><br \/>to most countries<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\u2b50<br \/><strong>1,400+ customers<\/strong><br \/><a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03b4\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2<\/a><\/div>\n<\/div>\n<h2>\ud83d\udd12 Why order Terbijohn from MedsBase<\/h2>\n<ul>\n<li><strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong> \u2014 sourced from a regulated facility, finished pack with batch number and expiry.<\/li>\n<li><strong>\u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/strong> \u2014 plain envelope, no medication name on the outside.<\/li>\n<li><strong>\u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae<\/strong> to most countries with <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance<\/a>.<\/li>\n<li><strong>Loyalty points<\/strong> \u2014 1 point per $1 spent (excludes peptides\/shipping); 100 points = $5 off your next order.<\/li>\n<\/ul>\n<h2 id=\"uses\">Uses &#038; indications<\/h2>\n<p>Terbijohn (terbinafine 250 mg, Johnlee Pharma) is the standard oral therapy for dermatophyte fungal infections of the skin and nails. It is fungicidal against dermatophytes (Trichophyton, Epidermophyton, Microsporum), fungistatic against most Candida species (so not used for yeast infections), and active against some moulds.<\/p>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Typical regimen<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Onychomycosis \u2014 fingernails<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">250 mg once daily \u00d7 6 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Onychomycosis \u2014 toenails<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">250 mg once daily \u00d7 12 weeks<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tinea capitis (scalp ringworm) \u2014 adults<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">250 mg once daily \u00d7 4 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tinea capitis \u2014 children &gt; 4 y<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Weight-based: 62.5 mg (10\u201320 kg) \/ 125 mg (20\u201340 kg) \/ 250 mg (&gt; 40 kg) once daily \u00d7 4 weeks<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tinea pedis \/ cruris \/ corporis (extensive or topical-refractory)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">250 mg once daily \u00d7 2\u20136 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tinea manuum<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">250 mg once daily \u00d7 2\u20134 weeks<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"how-to-take\">How to take<\/h2>\n<ul>\n<li>Take with or without food \u2014 absorption is not significantly affected.<\/li>\n<li>Take at the same time each day to maintain steady plasma levels.<\/li>\n<li>Do not stop early \u2014 even when the visible nail looks normal, dermatophytes may persist deep in the nail matrix.<\/li>\n<li>The dead, fungus-affected nail will keep growing out for 9\u201312 months after a successful 12-week course. This is normal.<\/li>\n<\/ul>\n<h2 id=\"mechanism\">\u03a0\u03ce\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af<\/h2>\n<p>Terbinafine inhibits squalene epoxidase \u2014 an enzyme earlier in the ergosterol biosynthesis pathway than the CYP51 target of azoles. This causes squalene to accumulate inside the fungal cell (toxic effect) AND ergosterol depletion (membrane disruption) \u2014 the dual mechanism is why terbinafine is fungicidal against dermatophytes. Highly lipophilic \u2014 concentrates in stratum corneum, hair follicles, sebum, and nail at concentrations many times plasma. Persists in the nail for weeks after dosing.<\/p>\n<h2 id=\"side-effects\">Side effects &#038; monitoring<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u03a3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Effects<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Very common (\u226510%)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Headache, gastrointestinal symptoms (nausea, abdominal pain, diarrhoea), mild rash<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u03a3\u03c5\u03c7\u03bd\u03ac<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\"><strong>Taste disturbance \/ loss of taste<\/strong> (~3% \u2014 usually reversible over weeks to months but can be persistent), arthralgia, myalgia<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u0391\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03b5\u03c2<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Hepatic enzyme rise, depression, peripheral neuropathy<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Severe hepatotoxicity (idiosyncratic, can be fatal \u2014 discontinue if AST\/ALT &gt; 3\u00d7 ULN or any symptoms), severe skin reactions (SJS, TEN, AGEP), drug-induced lupus, agranulocytosis, neutropenia<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:20px 0;border-radius:6px;\"><strong>Liver function monitoring<\/strong><\/p>\n<div>Check baseline LFTs before starting. Repeat at 4\u20136 weeks if treating &gt; 6 weeks. Stop terbinafine immediately if AST\/ALT &gt; 3\u00d7 ULN, or if symptomatic (jaundice, dark urine, persistent nausea, RUQ pain, severe fatigue). Most cases of severe hepatotoxicity occur within 4\u20136 weeks of starting.<\/div>\n<\/div>\n<h2 id=\"interactions\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<p>Terbinafine has fewer interactions than the azoles, but is a moderate inhibitor of CYP2D6:<\/p>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">Drug class<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u0391\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u0394\u03c1\u03ac\u03c3\u03b7<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Tricyclic antidepressants (amitriptyline, nortriptyline)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Levels rise \u2014 anticholinergic \/ cardiac toxicity<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Reduce dose; monitor<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">SSRIs \/ SNRIs (paroxetine, fluoxetine, venlafaxine, duloxetine)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Levels rise<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Monitor for serotonin syndrome \/ side effects<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Beta-blockers (metoprolol, propranolol, carvedilol)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Levels rise \u2014 bradycardia, hypotension<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Monitor pulse \/ BP<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Antiarrhythmics (flecainide, propafenone)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Levels rise \u2014 proarrhythmia<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Avoid combination if possible<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Codeine, tramadol<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Reduced analgesic effect (CYP2D6 activates these)<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Switch to morphine or non-opioid analgesia<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u03a1\u03b9\u03c6\u03b1\u03bc\u03c0\u03b9\u03ba\u03af\u03bd\u03b7<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Terbinafine clearance increased<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Increase terbinafine dose 50% or extend duration<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u0397 Cimetidine<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Reduces terbinafine clearance<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">No dose change usually needed<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">Caffeine<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Levels rise \u2014 jitteriness<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">Reduce caffeine intake<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"contraindications\">Who should not take oral terbinafine<\/h2>\n<ul>\n<li>Active or chronic liver disease \u2014 particularly cirrhosis, active hepatitis.<\/li>\n<li>Severe renal impairment (CrCl &lt; 50 mL\/min \u2014 limited data).<\/li>\n<li>Hypersensitivity to terbinafine.<\/li>\n<li>Caution in patients with autoimmune disease \u2014 terbinafine can precipitate cutaneous lupus.<\/li>\n<li>Caution in pregnancy and breastfeeding (limited data; defer treatment of onychomycosis until after).<\/li>\n<\/ul>\n<h2 id=\"pregnancy\">Pregnancy &#038; breastfeeding<\/h2>\n<p>Limited human pregnancy data. Animal studies do not show teratogenicity. Onychomycosis is not life-threatening \u2014 defer treatment until after pregnancy and breastfeeding. Terbinafine is excreted in breast milk; not recommended during breastfeeding except if benefit clearly outweighs risk.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>How long until my toenail looks normal?<\/h3>\n<p>The drug clears the fungus within the 12-week course but the dead, discoloured nail keeps growing out from the cuticle. Toenails take 9\u201312 months to look fully normal; fingernails 4\u20136 months. Photo at month 0, 3, 6, 12 to track objectively.<\/p>\n<h3>Why do I have to confirm it&#8217;s a dermatophyte first?<\/h3>\n<p>Terbinafine is highly active against dermatophytes (Trichophyton, Epidermophyton) but only weakly active against Candida and most non-dermatophyte moulds. ~50% of nail discolouration is something other than dermatophyte fungus (psoriasis, lichen planus, trauma, melanoma). A nail clipping for microscopy and culture (or PCR) before starting saves 12 weeks of useless therapy.<\/p>\n<h3>Why am I tasting metal \/ can&#8217;t taste my food?<\/h3>\n<p>Taste disturbance affects ~3% of patients on oral terbinafine. The mechanism is not fully understood. It is usually reversible over weeks to a few months after stopping, but ~10% of cases can be persistent or permanent. If taste change starts during therapy, balance the impact against the cure rate \u2014 sometimes worth completing the course, sometimes worth switching to itraconazole.<\/p>\n<h3>Terbinafine vs itraconazole \u2014 which one for my toenail?<\/h3>\n<p>Terbinafine is first-line for dermatophyte onychomycosis: higher cure rate (~76% vs ~63%), fewer drug interactions, no acid-absorption rule. Itraconazole pulse is preferred for non-dermatophyte mould or mixed Candida onychomycosis, or when terbinafine is contraindicated.<\/p>\n<h3>Can I drink alcohol while taking terbinafine?<\/h3>\n<p>Both alcohol and terbinafine are processed by the liver. Heavy drinking raises hepatotoxicity risk. Light intake is generally accepted; avoid binge-drinking and cut alcohol entirely if you have any pre-existing liver concern. A 12-week treatment course is a reasonable time to reduce alcohol intake.<\/p>\n<h3>What about my child with scalp ringworm?<\/h3>\n<p>Terbinafine is licensed for tinea capitis in children &gt; 4 years (weight-based dosing). For Trichophyton tonsurans (the common UK \/ US cause) it is first-line \u2014 4-week course, higher cure rate than griseofulvin and shorter duration. For Microsporum canis, griseofulvin is preferred.<\/p>\n<h3>I&#8217;ve had alopecia areata before \u2014 does terbinafine make it worse?<\/h3>\n<p>Terbinafine is rarely associated with new-onset hair loss (telogen effluvium). Pre-existing alopecia areata is not a contraindication. If significant hair loss develops, discuss with a dermatologist.<\/p>\n<h3>Why do my muscles ache on terbinafine?<\/h3>\n<p>Myalgia and arthralgia are recognised side effects (~5%). Usually mild and resolve on continuation. Severe muscle pain, dark urine, or weakness \u2014 stop the drug and seek medical advice (rare rhabdomyolysis or drug-induced myopathy).<\/p>\n<h3>Can I exercise on terbinafine?<\/h3>\n<p>Yes \u2014 normal exercise is fine. The mild myalgia some patients experience is not exercise-related. If you develop unusual leg pain or dark urine after exercise, hold the drug and get a CK level.<\/p>\n<h3>Is Terbijohn the same as Lamisil?<\/h3>\n<p>Yes \u2014 Lamisil is the original Novartis brand of terbinafine. Terbijohn contains the same active ingredient, manufactured by Johnlee Pharma under WHO-GMP. Bioequivalent.<\/p>\n<h2 id=\"storage\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>Store tablets at 15\u201330 \u00b0C, away from moisture and light. Keep in original blister. Do not use after expiry. Keep out of reach of children.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>Other Antifungal Medications you may be interested in<\/h2>\n<p>If Terbijohn is unavailable, here are alternatives \u2014 same molecule from a different manufacturer, plus options for indications where terbinafine is not first-line.<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/zimig\/\"><strong>Zimig (terbinafine 250 mg)<\/strong><\/a> \u2014 First-line for dermatophyte onychomycosis; ~76% cure rate.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/sporanox-capsule\/\"><strong>Sporanox (itraconazole 100 mg)<\/strong><\/a> \u2014 Pulse therapy for non-dermatophyte mould or mixed Candida onychomycosis.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/grisovin-fp\/\"><strong>Grisovin FP (griseofulvin)<\/strong><\/a> \u2014 Tinea capitis caused by Microsporum (paediatric).<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/loceryl-nail-liq\/\"><strong>Loceryl (amorolfine 5%)<\/strong><\/a> \u2014 Topical lacquer for mild distal-edge nail fungus.<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/zocon\/\"><strong>Zocon (fluconazole 150 mg)<\/strong><\/a> \u2014 Standard oral therapy for Candida (vaginal, oral, oesophageal thrush).<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 18px;margin:24px 0;font-size:0.95em;\"><strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd.<\/strong> This page is product information for adults ordering antifungal medicine for personal use. It is not a substitute for individual medical advice. Discuss the right antifungal, dose, and treatment duration with a qualified clinician \u2014 particularly if you have liver disease, are pregnant or breastfeeding, take warfarin, take a statin, take immunosuppressants, or have a fungal nail infection that may be a different diagnosis (psoriasis, lichen planus, trauma).<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>\u2705 Combats fungal infections<br \/>\n\u2705 Soothes itching and irritation<br \/>\n\u2705 Improves nail health<br \/>\n\u2705 Treats athlete&#8217;s foot<br \/>\n\u2705 Clears skin disorders<\/p>\n<p>Terbijohn contains Terbinafine.<\/p>","protected":false},"featured_media":59469,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3501,3141,3504,3342],"product_tag":[4701,3629],"class_list":{"0":"post-59468","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-fungal","7":"product_cat-category-overview","8":"product_cat-fungal-infection-treatment","9":"product_cat-general-health","10":"product_tag-terbijohn","11":"product_tag-terbinafine","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/59468","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=59468"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/59469"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=59468"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=59468"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=59468"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=59468"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}