{"id":59908,"date":"2024-02-28T06:23:19","date_gmt":"2024-02-28T06:23:19","guid":{"rendered":"https:\/\/medsname.com\/ondem-injection\/"},"modified":"2026-04-30T10:23:53","modified_gmt":"2026-04-30T10:23:53","slug":"ondem-injection","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/ondem-injection\/","title":{"rendered":"Ondem Injection"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Ondem Injection?<\/h3>\n<p style=\"margin:0;\"><strong>Ondem Injection<\/strong> \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 <strong>ondansetron 2 mg\/ml<\/strong> in 2 ml ampoules (4 mg total) &mdash; a selective serotonin <strong>5-HT3 receptor antagonist<\/strong> used in hospitals to prevent and treat <strong>chemotherapy-induced<\/strong>, <strong>radiation-induced<\/strong>, \u03ba\u03b1\u03b9 <strong>post-operative nausea and vomiting (PONV)<\/strong>. Administered by a healthcare professional intravenously (slow push or short infusion) or intramuscularly. Onset within 5&ndash;10 minutes IV. Manufactured by Alkem Laboratories &mdash; the generic equivalent of Zofran injection. <strong>FDA single-dose cap 16 mg IV<\/strong> due to QT signal at higher doses.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f6f8;border:1px solid #e1e4e8;border-radius:6px;padding:14px 18px;margin:24px 0;font-size:14px;\"><strong>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase:<\/strong> \u2714 <strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong> &#10004; Discreet packaging &#10004; Worldwide shipping &#10004; <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">Verified customer reviews (1,400+ customers)<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\"><strong>&#9888;&#65039; Hospital-only injection &mdash; not for self-administration.<\/strong> Parenteral ondansetron is administered by a healthcare professional in a clinical setting (chemotherapy unit, hospital theatre, emergency department) where ECG and resuscitation equipment are available. Self-administration is not appropriate. Single doses &gt; 16 mg IV have been associated with QT prolongation and torsades-de-pointes &mdash; the FDA dose cap is 16 mg per dose. Avoid in <strong>congenital long-QT syndrome<\/strong>, hypokalaemia, hypomagnesaemia, and with concurrent QT-prolonging drugs (azithromycin, citalopram, methadone, amiodarone, fluoroquinolones, antipsychotics, hydroxychloroquine). Apomorphine is an absolute contraindication.<\/div>\n<h3 class=\"wp-block-heading\">\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Ondem Injection is supplied from a <strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong>. Every order ships discreetly worldwide and is covered by our <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> &mdash; if it does not arrive within 20 business days, we reship at no cost. Ondem Injection is the global standard parenteral 5-HT3 antagonist for inpatient antiemesis. Alkem is one of India&rsquo;s largest WHO-GMP injectable manufacturers and the formulation is bioequivalent to the reference brand.<\/p>\n<h2 class=\"wp-block-heading\">\u039c\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2<\/h2>\n<p>Chemotherapy, radiation, and surgical stress damage gut enterochromaffin cells, releasing massive amounts of <strong>serotonin (5-HT)<\/strong>. The serotonin binds 5-HT3 receptors on vagal afferents and on the chemoreceptor trigger zone (area postrema), generating the strongest known oral\/intestinal emetic stimulus. Ondansetron is a highly selective antagonist at the 5-HT3 receptor &mdash; it interrupts this signal at both peripheral and central sites without affecting D2, H1, muscarinic, or alpha-adrenergic receptors. The clean receptor profile explains the absence of sedation, extrapyramidal reactions, and anticholinergic side effects that limit older antiemetics like prochlorperazine and metoclopramide.<\/p>\n<h2 class=\"wp-block-heading\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>CINV:<\/strong> moderately or highly emetogenic chemotherapy &mdash; usually with dexamethasone &plusmn; aprepitant for highly emetogenic regimens.<\/li>\n<li><strong>Radiation-induced nausea:<\/strong> total body irradiation, high-dose abdominal\/pelvic radiation.<\/li>\n<li><strong>Post-operative nausea and vomiting (PONV):<\/strong> single 4 mg dose at induction or end of surgery; prophylaxis for high-risk patients (Apfel score &ge; 2).<\/li>\n<li><strong>Severe gastroenteritis<\/strong> in patients unable to retain oral fluids.<\/li>\n<li><strong>Refractory hyperemesis gravidarum<\/strong> &mdash; second\/third-line after doxylamine+B6 and metoclopramide.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0394\u03cc\u03c3\u03b7<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th style=\"padding:8px;text-align:left;\">\u0394\u03cc\u03c3\u03b7<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">CINV (highly emetogenic)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">8 mg slow IV (over &gt; 15 min) 30 min before chemo, then 8 mg every 4 h &times; 2 doses, then transition to oral 8 mg every 12 h<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">CINV (moderately emetogenic)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">8 mg slow IV 30 min before chemo, then transition to oral<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">PONV (adult)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">4 mg slow IV at induction or end of surgery (single dose); some protocols 8 mg for high-risk<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Paediatric (CINV)<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">5 mg\/m&sup2; IV before chemo (max 8 mg per dose); weight-based for gastroenteritis<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">Single-dose maximum<\/td>\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">16 mg IV (FDA cap due to QT signal); slow IV push over 30 sec or short infusion 15 min<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border-bottom:1px solid #ddd;\">\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/td>\n<td style=\"padding:8px;\">Maximum 8 mg\/day (Child-Pugh C)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Compatible with 0.9% sodium chloride and 5% dextrose; do not mix in the same syringe with other drugs. Administer slow IV (over 30 seconds for push or 15 min for infusion) &mdash; rapid bolus increases the QT signal.<\/p>\n<h2 class=\"wp-block-heading\">\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> headache (often within minutes of injection), constipation, mild flushing, transient AST\/ALT rise, fatigue<\/li>\n<li><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> dizziness, hot flushes, hiccups, mild bradycardia, hypotension after rapid IV<\/li>\n<li><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b5\u03c2 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2:<\/strong> QT prolongation\/torsades (especially with single doses &gt; 16 mg), serotonin syndrome (with SSRIs\/SNRIs\/triptans), severe hypersensitivity, transient blindness (very rare), arrhythmia<\/li>\n<li><strong>\u0391\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03b5\u03c2:<\/strong> extrapyramidal reactions (rare with ondansetron unlike older antiemetics)<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<ul>\n<li><strong>Apomorphine:<\/strong> ABSOLUTE contraindication &mdash; severe hypotension and loss of consciousness reported.<\/li>\n<li><strong>\u0386\u03bb\u03bb\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03bc\u03b7\u03ba\u03cd\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf QT<\/strong> (azithromycin, clarithromycin, citalopram, escitalopram, methadone, amiodarone, sotalol, fluoroquinolones, hydroxychloroquine, antipsychotics): avoid combination or monitor ECG.<\/li>\n<li><strong>Serotonergic drugs<\/strong> (SSRIs, SNRIs, MAOIs, triptans, tramadol, fentanyl, linezolid, methylene blue): rare serotonin syndrome reported.<\/li>\n<li><strong>\u0399\u03c3\u03c7\u03c5\u03c1\u03bf\u03af \u03b5\u03c0\u03b1\u03b3\u03c9\u03b3\u03b5\u03af\u03c2 CYP3A4<\/strong> (rifampicin, phenytoin, carbamazepine): may lower ondansetron levels and reduce efficacy.<\/li>\n<li><strong>Tramadol:<\/strong> ondansetron may reduce tramadol analgesic effect (5-HT3 blockade interferes with descending pain inhibition).<\/li>\n<\/ul>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">How quickly does Ondem Injection work?<\/h3>\n<p>Onset is within 5&ndash;10 minutes after slow IV push and 15&ndash;30 minutes after IM injection. Antiemetic effect lasts 8&ndash;12 hours. The IV form is preferred for active vomiting where oral routes are unreliable.<\/p>\n<h3 class=\"wp-block-heading\">Why is the IV ondansetron dose capped at 16 mg?<\/h3>\n<p>FDA review of cardiac safety data found that single IV doses &gt; 16 mg significantly increase the risk of QT prolongation and torsades-de-pointes. The 16 mg cap applies to single doses; total daily dose can still be 24 mg given as 8 mg every 8 hours.<\/p>\n<h3 class=\"wp-block-heading\">Can Ondem Injection be given IM?<\/h3>\n<p>Yes &mdash; IM is a reasonable route when IV access is difficult, with onset 15&ndash;30 minutes (slower than IV but faster than oral). The standard IM dose is 4 mg; do not exceed 16 mg per single dose.<\/p>\n<h3 class=\"wp-block-heading\">Can Ondem Injection be used in pregnancy?<\/h3>\n<p>Reserved for refractory hyperemesis gravidarum after doxylamine+B6 and metoclopramide have failed. Some observational studies suggest a small first-trimester cardiac and cleft-palate signal &mdash; weigh against the maternal risk of severe untreated hyperemesis. Specialist supervision recommended.<\/p>\n<h3 class=\"wp-block-heading\">Is Ondem Injection safe in children?<\/h3>\n<p>Yes &mdash; weight or BSA-based dosing is well established for paediatric chemotherapy and severe gastroenteritis. The dose is typically 5 mg\/m&sup2; IV before chemo (max 8 mg) or weight-based (0.15 mg\/kg) for gastroenteritis.<\/p>\n<h3 class=\"wp-block-heading\">Why does Ondem Injection cause constipation?<\/h3>\n<p>5-HT3 receptors in the gut wall regulate gut motility &mdash; blocking them reduces peristalsis and slows colonic transit. Constipation is the most clinically meaningful side effect; pre-empt with hydration, fibre, and prophylactic laxatives during multi-day chemo courses.<\/p>\n<h3 class=\"wp-block-heading\">Does Ondem Injection cause sedation?<\/h3>\n<p>No. Unlike promethazine, prochlorperazine, and metoclopramide, ondansetron does not cause sedation, extrapyramidal reactions, or anticholinergic side effects.<\/p>\n<h3 class=\"wp-block-heading\">Can Ondem Injection be mixed with chemotherapy in the same line?<\/h3>\n<p>Ondansetron is incompatible with several chemotherapy agents in the same syringe; flush the line with normal saline between drugs. Compatibility is product-specific and should be checked against pharmacy guidelines for each chemotherapy combination.<\/p>\n<h3 class=\"wp-block-heading\">What if a single dose &gt; 16 mg is needed?<\/h3>\n<p>For highly emetogenic chemotherapy, give 8 mg slow IV every 4 hours rather than a single high dose. Switching to a different 5-HT3 (granisetron, palonosetron) or adding an NK1 antagonist (aprepitant) is usually a better strategy than exceeding the 16 mg single-dose cap.<\/p>\n<h3 class=\"wp-block-heading\">How is Ondem Injection stored?<\/h3>\n<p>Store ampoules at room temperature (15&ndash;25&deg;C), protect from light. Do not freeze. Inspect the solution before use &mdash; it should be clear and colourless.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Other Nausea Treatments<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/ondem\/\">Ondem (ondansetron oral tablet &mdash; oral switch after IV)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/emeset-4-odt\/\">Emeset 4 ODT (oral disintegrating &mdash; transition from IV)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/granicip\/\">Granicip (granisetron &mdash; once-daily 5-HT3)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/dompewal-tablet\/\">Dompewal (domperidone &mdash; alternative class)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/stemetil-md\/\">Stemetil MD (prochlorperazine ODT &mdash; rescue antiemetic)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/nausea-treatment\/\"><strong>Browse all Nausea Treatments<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u0391\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u0395\u03c5\u03b8\u03cd\u03bd\u03b7\u03c2.<\/strong> This page is for informational purposes only and does not replace medical advice from a qualified healthcare professional. Persistent vomiting, blood in vomit, severe abdominal pain, signs of dehydration, suspected pregnancy complications, or chemotherapy-related symptoms require evaluation by a clinician.<\/div>","protected":false},"excerpt":{"rendered":"<p>Ondem Injection (Ondansetron 2 mg\/ml, 4 mg per 2 ml ampoule) \u2014 hospital-administered IV\/IM 5-HT3 antagonist for chemotherapy, radiation, and post-operative nausea. Alkem generic of Zofran injection.<\/p>","protected":false},"featured_media":59909,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3543],"product_tag":[3613,4766],"class_list":{"0":"post-59908","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-nausea-treatment","9":"product_tag-ondansetron","10":"product_tag-ondem-injection","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/59908","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=59908"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/59909"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=59908"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=59908"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=59908"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=59908"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}