{"id":59954,"date":"2024-02-28T06:25:37","date_gmt":"2024-02-28T06:25:37","guid":{"rendered":"https:\/\/medsname.com\/palip-xr\/"},"modified":"2026-04-30T10:23:52","modified_gmt":"2026-04-30T10:23:52","slug":"palip-xr","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/palip-xr\/","title":{"rendered":"Palip XR"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fff8d6;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<h3 style=\"margin-top:0;\">\u26a1 \u0393\u03c1\u03ae\u03b3\u03bf\u03c1\u03b7 \u0391\u03c0\u03ac\u03bd\u03c4\u03b7\u03c3\u03b7<\/h3>\n<p style=\"margin-bottom:0;\">\u03a4\u03bf Palip XR (Paliperidone 3 \/ 6 \/ 9 mg XR, \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03c3\u03b7\u03c2) \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03ac\u03c4\u03c5\u03c0\u03bf \u03b1\u03bd\u03c4\u03b9\u03c8\u03c5\u03c7\u03c9\u03c3\u03b9\u03ba\u03cc \u03b3\u03b9\u03b1 \u03c3\u03c7\u03b9\u03b6\u03bf\u03c6\u03c1\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c7\u03b9\u03b6\u03bf\u03b1\u03c6\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae. \u0395\u03bd\u03b5\u03c1\u03b3\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7\u03c2, \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1 \u03bc\u03ad\u03c3\u03c9 \u03b4\u03b9\u03c3\u03ba\u03af\u03bf\u03c5 OROS \u03c9\u03c3\u03bc\u03c9\u03c4\u03b9\u03ba\u03ae\u03c2 \u03b1\u03bd\u03c4\u03bb\u03af\u03b1\u03c2. \u0391\u03c0\u03bf\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ac \u2014 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03b4\u03cc\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03bf Palip XR \u03c3\u03c4\u03bf MedsBase \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03b5\u03c5\u03b8\u03b5\u03af\u03b1\u03c2 \u03b1\u03c0\u03cc \u03ad\u03bd\u03b1\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf\u03bd WHO-GMP \u03c3\u03b5 \u03b1\u03c0\u03bb\u03ae, \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> \u2014 \u03c0\u03b1\u03c1\u03ac\u03b8\u03c5\u03c1\u03bf \u03ac\u03c6\u03b9\u03be\u03b7\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd \u03ae \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c7\u03c9\u03c1\u03af\u03c2 \u03c7\u03c1\u03ad\u03c9\u03c3\u03b7 \u2014 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03ba\u03b1\u03b9\u03bf\u03cd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03bf\u03c7\u03ae \u03c3\u03c4\u03bf <a href=\"https:\/\/medsbase.com\/el\/loyalty-points\/\">\u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1 \u03b1\u03c6\u03bf\u03c3\u03af\u03c9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>. \u0394\u03b9\u03b1\u03c4\u03af\u03b8\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c3\u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c0\u03c1\u03bf\u03bf\u03c1\u03b9\u03c3\u03bc\u03bf\u03cd\u03c2.<\/p>\n<h2>\u03a4\u03b9 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf Palip XR \u03ba\u03b1\u03b9 \u03c0\u03ce\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b5\u03af<\/h2>\n<p>\u03a4\u03bf Palip XR \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03b5\u03ba\u03c4\u03b1\u03c4\u03bf\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b1\u03c0\u03bf\u03b4\u03ad\u03c3\u03bc\u03b5\u03c5\u03c3\u03b7\u03c2 \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 Sun Pharma. \u0394\u03b9\u03b1\u03b8\u03ad\u03c3\u03b9\u03bc\u03b5\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2: <strong>3 \/ 6 \/ 9 mg XR<\/strong>. \u0397 \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03ba\u03cd\u03c1\u03b9\u03bf \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b7 \u03c4\u03b7\u03c2 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7\u03c2 (9-\u03c5\u03b4\u03c1\u03bf\u03be\u03c5\u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7). \u03a6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03c0\u03bf\u03bb\u03cd \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u2014 \u03b9\u03c3\u03c7\u03c5\u03c1\u03ae \u03b1\u03bd\u03c4\u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 D2 \u03ba\u03b1\u03b9 5-HT2A \u03c5\u03c0\u03bf\u03b4\u03bf\u03c7\u03b5\u03af\u03c2, \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b1\u03ba\u03c4\u03af\u03bd\u03b7\u03c2, EPS \u03c3\u03b5 \u03c5\u03c8\u03b7\u03bb\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u2014 \u03b1\u03bb\u03bb\u03ac \u03bc\u03b5 \u03b4\u03cd\u03bf \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2: (1) \u03b7 \u03c6\u03cc\u03c1\u03bc\u03bf\u03c5\u03bb\u03b1 \u03b5\u03ba\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b1\u03c0\u03bf\u03b4\u03ad\u03c3\u03bc\u03b5\u03c5\u03c3\u03b7\u03c2 OROS \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03b5\u03af \u03bc\u03b9\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b7 \u03ba\u03b1\u03bc\u03c0\u03cd\u03bb\u03b7 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 24 \u03c9\u03c1\u03ce\u03bd (\u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03bd\u03bf\u03c7\u03ae \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 IR), \u03ba\u03b1\u03b9 (2) \u03b7 \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03b5\u03ba\u03ba\u03c1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ac (75%) \u03b1\u03bd\u03c4\u03af \u03bd\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ac, \u03b5\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2 \u03b4\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bb\u03bb\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03b1 CYP \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03b4\u03cc\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1.<\/p>\n<h2>\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th>\u0395\u03ba\u03ba\u03af\u03bd\u03b7\u03c3\u03b7<\/th>\n<th>\u03a3\u03c4\u03cc\u03c7\u03bf\u03c2<\/th>\n<th>\u039c\u03ad\u03b3\u03b9\u03c3\u03c4\u03bf<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u03a3\u03c7\u03b9\u03b6\u03bf\u03c6\u03c1\u03ad\u03bd\u03b5\u03b9\u03b1 (\u03b5\u03bd\u03ae\u03bb\u03b9\u03ba\u03b5\u03c2)<\/td>\n<td>6 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1 \u03c4\u03bf \u03c0\u03c1\u03c9\u03af<\/td>\n<td>3\u201312 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>12 mg<\/td>\n<\/tr>\n<tr>\n<td>\u03a3\u03c7\u03b9\u03b6\u03bf\u03c6\u03c1\u03ad\u03bd\u03b5\u03b9\u03b1 (\u03b5\u03c6\u03ae\u03b2\u03bf\u03c5\u03c2 \u2265 12 \u03b5\u03c4\u03ce\u03bd, \u2265 51 \u03ba\u03b9\u03bb\u03ac)<\/td>\n<td>3 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>3\u201312 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>12 mg<\/td>\n<\/tr>\n<tr>\n<td>\u03a3\u03c7\u03b9\u03b6\u03bf\u03b8\u03c5\u03bc\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae<\/td>\n<td>6 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>3\u201312 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>12 mg<\/td>\n<\/tr>\n<tr>\n<td>\u039d\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 (CrCl 50\u201380)<\/td>\n<td>3 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>\u03ad\u03c9\u03c2 6 mg<\/td>\n<td>6 mg<\/td>\n<\/tr>\n<tr>\n<td>\u039d\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 (CrCl 10\u201350)<\/td>\n<td>1.5 mg \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>\u03ad\u03c9\u03c2 3 mg<\/td>\n<td>3 mg<\/td>\n<\/tr>\n<tr>\n<td>\u039d\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 (CrCl &lt; 10)<\/td>\n<td>\u03b4\u03b5\u03bd \u03c3\u03c5\u03bd\u03b9\u03c3\u03c4\u03ac\u03c4\u03b1\u03b9<\/td>\n<td>\u2014<\/td>\n<td>\u2014<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u03a0\u03b1\u03af\u03c1\u03bd\u03b5\u03c4\u03b5 \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03bf \u2014 \u03bc\u03b7 \u03c3\u03c5\u03bd\u03b8\u03bb\u03af\u03b2\u03b5\u03c4\u03b5, \u03bc\u03b1\u03c3\u03ac\u03c4\u03b5 \u03ae \u03c3\u03c0\u03ac\u03c4\u03b5. \u03a4\u03bf \u03ba\u03ad\u03bb\u03c5\u03c6\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03bb\u03af\u03b1\u03c2 \u03ce\u03c3\u03bc\u03c9\u03c3\u03b7\u03c2 OROS \u03b8\u03b1 \u03c0\u03b5\u03c1\u03ac\u03c3\u03b5\u03b9 \u03ac\u03b8\u03b9\u03ba\u03c4\u03bf \u03c3\u03c4\u03b1 \u03ba\u03cc\u03c0\u03c1\u03b1\u03bd\u03b1 \u2014 \u03b1\u03c5\u03c4\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03b1\u03bd\u03b1\u03bc\u03b5\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf.<\/p>\n<h2>\u03a3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c3\u03c6\u03b1\u03bb\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03ba\u03c4\u03b9\u03bc\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>FDA \u03bc\u03b1\u03cd\u03c1\u03bf \u03ba\u03bf\u03c5\u03c4\u03af \u2014 \u03c8\u03cd\u03c7\u03c9\u03c3\u03b7 \u03c3\u03c7\u03b5\u03c4\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bc\u03b5 \u03ac\u03bd\u03bf\u03b9\u03b1<\/strong><\/p>\n<p style=\"margin-bottom:0;\">\u038c\u03bb\u03b1 \u03c4\u03b1 \u03b1\u03c4\u03c5\u03c0\u03b9\u03ba\u03ac \u03b1\u03bd\u03c4\u03b9\u03c8\u03c5\u03c7\u03c9\u03c3\u03b9\u03ba\u03ac \u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03bc\u03b1\u03cd\u03c1\u03bf\u03c5 \u03ba\u03bf\u03c5\u03c4\u03b9\u03bf\u03cd \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd FDA \u03b3\u03b9\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b8\u03bd\u03b7\u03c3\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 (\u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae \u03ba\u03b1\u03b9 \u03bb\u03bf\u03b9\u03bc\u03ce\u03b4\u03b7\u03c2) \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03c3\u03c5\u03bc\u03c0\u03b5\u03c1\u03b9\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae\u03c2 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae\u03c2 \u03c3\u03b5 \u03b7\u03bb\u03b9\u03ba\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03bc\u03b5 \u03ac\u03bd\u03bf\u03b9\u03b1. <strong>\u03a4\u03b1 \u03b1\u03c4\u03c5\u03c0\u03b9\u03ba\u03ac \u03b4\u03b5\u03bd \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03b3\u03ba\u03c1\u03b9\u03b8\u03b5\u03af \u03b3\u03b9\u03b1 \u03c8\u03cd\u03c7\u03c9\u03c3\u03b7 \u03ae \u03b1\u03bd\u03b1\u03c3\u03c4\u03ac\u03c4\u03c9\u03c3\u03b7 \u03c3\u03c7\u03b5\u03c4\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03b7 \u03bc\u03b5 \u03ac\u03bd\u03bf\u03b9\u03b1.<\/strong>. \u0397 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03cc\u03bd \u03c4\u03bf\u03bd \u03c0\u03bb\u03b7\u03b8\u03c5\u03c3\u03bc\u03cc \u03b5\u03af\u03bd\u03b1\u03b9 \u03b5\u03ba\u03c4\u03cc\u03c2 \u03b5\u03c4\u03b9\u03ba\u03ad\u03c4\u03b1\u03c2, \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03bb\u03cd\u03c3\u03b7, \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b4\u03b9\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c3\u03b1\u03c6\u03ae \u03c3\u03c5\u03b6\u03ae\u03c4\u03b7\u03c3\u03b7 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5-\u03bf\u03c6\u03ad\u03bb\u03bf\u03c5\u03c2.<\/p>\n<\/div>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>\u03a5\u03c0\u03b5\u03c1\u03c0\u03c1\u03bf\u03bb\u03b1\u03ba\u03c4\u03b9\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 (\u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03bc\u03b5 \u03c4\u03b7 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7)<\/strong><\/p>\n<p style=\"margin-bottom:0;\">\u03a9\u03c2 \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7\u03c2, \u03b7 \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b1\u03ba\u03c4\u03af\u03bd\u03b7\u03c2: \u03b1\u03bc\u03b7\u03bd\u03cc\u03c1\u03c1\u03bf\u03b9\u03b1, \u03b3\u03b1\u03bb\u03b1\u03ba\u03c4\u03cc\u03c1\u03c1\u03bf\u03b9\u03b1, \u03c3\u03b5\u03be\u03bf\u03c5\u03b1\u03bb\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03b7 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03c0\u03c5\u03ba\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03c9\u03bd \u03bf\u03c3\u03c4\u03ce\u03bd. \u03a0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03ae\u03c3\u03c4\u03b5 \u03cc\u03c0\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03b7 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7\u00b7 \u03b1\u03bb\u03bb\u03ac\u03be\u03c4\u03b5 \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03b1\u03c4\u03c5\u03c0\u03b9\u03ba\u03cc \u03c0\u03bf\u03c5 \u03b4\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03bb\u03b1\u03ba\u03c4\u03af\u03bd\u03b7 (\u03b1\u03c1\u03b9\u03c0\u03b9\u03c0\u03c1\u03b1\u03b6\u03cc\u03bb\u03b7, \u03ba\u03b5\u03c4\u03b9\u03b5\u03c0\u03af\u03bd\u03b7) \u03b5\u03ac\u03bd \u03b5\u03bc\u03c6\u03b1\u03bd\u03b9\u03c3\u03c4\u03bf\u03cd\u03bd \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1.<\/p>\n<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>EPS \/ \u03b4\u03bf\u03c3\u03bf\u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bc\u03b5\u03bd\u03b1<\/strong><\/p>\n<p style=\"margin-bottom:0;\">\u03a0\u03ac\u03bd\u03c9 \u03b1\u03c0\u03cc 6 mg\/\u03b7\u03bc\u03ad\u03c1\u03b1, \u03c4\u03b1 EPS \u03ba\u03b1\u03b9 \u03b7 \u03b1\u03ba\u03b1\u03b8\u03b9\u03c3\u03af\u03b1 \u03b1\u03c5\u03be\u03ac\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c3\u03c5\u03c7\u03bd\u03cc\u03c4\u03b7\u03c4\u03b1. \u0395\u03be\u03b1\u03c1\u03c4\u03ac\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7.<\/p>\n<\/div>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 18px;margin:18px 0;border-radius:4px;\">\n<strong>\u03a0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc\u03c6\u03c1\u03b1\u03be\u03b7<\/strong><\/p>\n<p style=\"margin-bottom:0;\">\u03a4\u03bf \u03bc\u03b7 \u03c0\u03b1\u03c1\u03b1\u03bc\u03bf\u03c1\u03c6\u03ce\u03c3\u03b9\u03bc\u03bf \u03b4\u03b9\u03c3\u03ba\u03af\u03bf OROS \u03b5\u03af\u03bd\u03b1\u03b9 \u03b8\u03b5\u03c9\u03c1\u03b7\u03c4\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf\u03b2\u03bb\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c3\u03b5 \u03c0\u03c1\u03bf\u03cb\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03c3\u03b5\u03c2 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03c3\u03c4\u03ad\u03bd\u03c9\u03c3\u03b5\u03b9\u03c2 (\u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c3\u03c4\u03ad\u03bd\u03c9\u03b5\u03c2 Crohn, \u03c3\u03c4\u03ad\u03bd\u03c9\u03c3\u03b7 \u03bf\u03b9\u03c3\u03bf\u03c6\u03ac\u03b3\u03bf\u03c5, \u03c0\u03c1\u03bf\u03b7\u03b3\u03bf\u03cd\u03bc\u03b5\u03bd\u03b7 \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ae \u03b5\u03ba\u03c4\u03bf\u03bc\u03ae). \u03a3\u03c0\u03ac\u03bd\u03b9\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac, \u03b1\u03bb\u03bb\u03ac \u03b1\u03be\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c3\u03b7\u03bc\u03b5\u03b9\u03c9\u03b8\u03b5\u03af.<\/p>\n<\/div>\n<h2>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>\u03a5\u03c0\u03b5\u03c1\u03c0\u03c1\u03bf\u03bb\u03b1\u03ba\u03c4\u03b9\u03bd\u03b1\u03b9\u03bc\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b1\u03ba\u03cc\u03bb\u03bf\u03c5\u03b8\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1<\/strong> \u2014 \u03af\u03b4\u03b9\u03bf \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03bc\u03b5 \u03c4\u03b7 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7.<\/li>\n<li><strong>\u0391\u03ba\u03b1\u03b8\u03b9\u03c3\u03af\u03b1, EPS<\/strong> \u2014 \u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7.<\/li>\n<li><strong>\u03a5\u03c0\u03bd\u03b7\u03bb\u03af\u03b1, \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae<\/strong> \u2014 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1.<\/li>\n<li><strong>\u0391\u03cd\u03be\u03b7\u03c3\u03b7 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2<\/strong> \u2014\u2014 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 (2\u20134 kg \/ 6 \u03bc\u03ae\u03bd\u03b5\u03c2).<\/li>\n<li><strong>\u039f\u03c1\u03b8\u03bf\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ae \u03c5\u03c0\u03cc\u03c4\u03b1\u03c3\u03b7<\/strong> \u2014 \u03c3\u03c5\u03c7\u03bd\u03ae \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7.<\/li>\n<li><strong>\u0395\u03c0\u03ad\u03ba\u03c4\u03b1\u03c3\u03b7 QT<\/strong> \u2014 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03b5\u03be\u03b1\u03c1\u03c4\u03ce\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b4\u03cc\u03c3\u03b7.<\/li>\n<\/ul>\n<h2>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<ul>\n<li><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b5\u03c0\u03b7\u03c1\u03b5\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc CYP \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2\/\u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03b9\u03b7\u03c4\u03ad\u03c2<\/strong> \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 (75% \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b5\u03ba\u03ba\u03c1\u03af\u03c3\u03b7).<\/li>\n<li><strong>\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b5\u03c0\u03b9\u03bc\u03b7\u03ba\u03cd\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf QT<\/strong> \u2014 \u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03bf\u03c2 \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2.<\/li>\n<li><strong>\u0391\u03bd\u03c4\u03b9\u03c5\u03c0\u03c1\u03b5\u03c3\u03c3\u03b9\u03ba\u03ac, \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b1\u03bb\u03c4\u03b9\u03ba\u03ac \u03c4\u03bf\u03c5 \u039a\u039d\u03a3, \u03b1\u03bd\u03c4\u03b9\u03ba\u03bf\u03bb\u03b9\u03bd\u03b5\u03c1\u03b3\u03b9\u03ba\u03ac<\/strong> \u2014 \u03b1\u03b8\u03c1\u03bf\u03b9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03bf\u03bc\u03ac\u03b4\u03b1\u03c2.<\/li>\n<li><strong>\u0399\u03c3\u03c7\u03c5\u03c1\u03bf\u03af \u03b5\u03c0\u03b1\u03b3\u03c9\u03b3\u03b5\u03af\u03c2 CYP3A4 + P-gp<\/strong> (\u03ba\u03b1\u03c1\u03b2\u03b1\u03bc\u03b1\u03b6\u03b5\u03c0\u03af\u03bd\u03b7, \u03c1\u03b9\u03c6\u03b1\u03bc\u03c0\u03b9\u03ba\u03af\u03bd\u03b7, \u03c6\u03b1\u03b9\u03bd\u03c5\u03c4\u03bf\u0390\u03bd\u03b7) \u2014 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b5\u03c0\u03b9\u03c0\u03ad\u03b4\u03c9\u03bd \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7\u03c2.<\/li>\n<\/ul>\n<h2>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7, \u03b8\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2, \u03c0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae<\/h2>\n<p>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7: \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1\u00b7 \u03b7 \u03ad\u03ba\u03b8\u03b5\u03c3\u03b7 \u03c3\u03c4\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03c3\u03c4\u03ac\u03b4\u03b9\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03ad\u03c3\u03b5\u03b9 \u03bd\u03b5\u03bf\u03b3\u03bd\u03b9\u03ba\u03ac EPS. \u0398\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2: \u03c0\u03b5\u03c1\u03bd\u03ac \u03c3\u03c4\u03bf \u03b3\u03ac\u03bb\u03b1\u00b7 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03cd\u03b8\u03b7\u03c3\u03b7. \u03a0\u03b1\u03b9\u03b4\u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae: \u03b1\u03b4\u03b5\u03b9\u03bf\u03b4\u03bf\u03c4\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc 12 \u03b5\u03c4\u03ce\u03bd (\u03c3\u03c7\u03b9\u03b6\u03bf\u03c6\u03c1\u03ad\u03bd\u03b5\u03b9\u03b1, \u2265 51 kg).<\/p>\n<h2>\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>\u0391\u03c0\u03bf\u03b8\u03b7\u03ba\u03b5\u03cd\u03c3\u03c4\u03b5 \u03c3\u03b5 \u03b8\u03b5\u03c1\u03bc\u03bf\u03ba\u03c1\u03b1\u03c3\u03af\u03b1 15\u201330 \u00b0C \u03c3\u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>\u03a0\u03ce\u03c2 \u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c4\u03bf Palip XR \u03b1\u03c0\u03cc \u03c4\u03b7 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7;<\/h3>\n<p>\u0397 \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03ba\u03cd\u03c1\u03b9\u03bf \u03b5\u03bd\u03b5\u03c1\u03b3\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b7 \u03c4\u03b7\u03c2 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7\u03c2 \u2014 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ac \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b5\u03c2. \u039f\u03b9 \u03b4\u03cd\u03bf \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2: (1) \u03b7 \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1 \u03b4\u03cc\u03c3\u03b7 OROS \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03b9 \u03c0\u03b9\u03bf \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c0\u03bb\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03b1\u03bd\u03bf\u03c7\u03ae \u03c3\u03b5 \u03c3\u03cd\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03bc\u03b5 \u03c4\u03b7 BID \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 IR\u00b7 (2) \u03b7 \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03b5\u03ba\u03ba\u03c1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ac, \u03b5\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2 \u03b4\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03bf\u03cd\u03bd \u03bc\u03b5 \u03c4\u03bf CYP \u03b1\u03bb\u03bb\u03ac \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c4\u03bf \u03ac\u03b4\u03b5\u03b9\u03bf \u03ba\u03ad\u03bb\u03c5\u03c6\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b4\u03b9\u03c3\u03ba\u03af\u03bf\u03c5 \u03c3\u03c4\u03b1 \u03ba\u03cc\u03c0\u03c1\u03b1\u03bd\u03ac \u03bc\u03bf\u03c5;<\/h3>\n<p>\u03a4\u03bf \u03b4\u03b9\u03c3\u03ba\u03af\u03bf OROS (\u03c3\u03cd\u03c3\u03c4\u03b7\u03bc\u03b1 \u03c0\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae\u03c2 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 \u03bc\u03b5 \u03b5\u03bb\u03b5\u03b3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03c3\u03b7 \u03bc\u03b5 \u03c9\u03c3\u03bc\u03c9\u03c4\u03b9\u03ba\u03cc \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc) \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03bc\u03b7 \u03c0\u03b1\u03c1\u03b1\u03bc\u03bf\u03c1\u03c6\u03ce\u03c3\u03b9\u03bc\u03bf \u03ba\u03ad\u03bb\u03c5\u03c6\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03c3\u03b5 \u03bc\u03b9\u03b1 \u03b7\u03bc\u03b9\u03c0\u03b5\u03c1\u03b1\u03c4\u03ae \u03bc\u03b5\u03bc\u03b2\u03c1\u03ac\u03bd\u03b7. \u03a4\u03bf \u03bd\u03b5\u03c1\u03cc \u03b5\u03b9\u03c3\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c1\u03b3\u03ac, \u03c9\u03b8\u03ce\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03bc\u03ad\u03c3\u03b1 \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03c4\u03c1\u03c5\u03c0\u03b7\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b5 \u03bb\u03ad\u03b9\u03b6\u03b5\u03c1 \u03bf\u03c0\u03ae. \u03a4\u03bf \u03ac\u03b4\u03b5\u03b9\u03bf \u03ba\u03ad\u03bb\u03c5\u03c6\u03bf\u03c2 \u03c0\u03b5\u03c1\u03bd\u03ac\u03b5\u03b9 \u03ac\u03b8\u03b9\u03ba\u03c4\u03bf \u2014 \u03b1\u03c5\u03c4\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03c3\u03c7\u03b5\u03b4\u03af\u03b1\u03c3\u03b7, \u03cc\u03c7\u03b9 \u03c0\u03c1\u03cc\u03b2\u03bb\u03b7\u03bc\u03b1. \u039c\u03b7\u03bd \u03b4\u03b9\u03b1\u03ba\u03cc\u03c8\u03b5\u03c4\u03b5 \u03c4\u03bf \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \u03bb\u03cc\u03b3\u03c9 \u03b1\u03c5\u03c4\u03bf\u03cd.<\/p>\n<h3>\u0395\u03af\u03bd\u03b1\u03b9 \u03b7 \u03bc\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1 LAI \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03b1\u03c0\u03cc \u03c4\u03bf \u03c0\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03ba\u03cc \u03b4\u03b9\u03c3\u03ba\u03af\u03bf;<\/h3>\n<p>\u0397 \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03c0\u03b1\u03bb\u03bc\u03b9\u03c4\u03b9\u03ba\u03cc (Invega Sustenna \u03bc\u03b7\u03bd\u03b9\u03b1\u03af\u03b1, Trinza \u03c4\u03c1\u03b9\u03bc\u03b7\u03bd\u03b9\u03b1\u03af\u03b1, Hafyera \u03b5\u03be\u03b1\u03bc\u03b7\u03bd\u03b9\u03b1\u03af\u03b1) \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf depot \u03b5\u03bd\u03ad\u03c3\u03b9\u03bc\u03bf LAI. \u03a4\u03bf \u03c0\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03ba\u03cc \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03ad\u03bd\u03b1\u03c1\u03be\u03b7, \u03c4\u03bf\u03bd \u03c4\u03b9\u03c4\u03bb\u03bf\u03b4\u03cc\u03c4\u03b7\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03c4\u03b9\u03bc\u03bf\u03cd\u03bd \u03c4\u03b7\u03bd \u03c0\u03c1\u03bf\u03c6\u03bf\u03c1\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1. \u03a4\u03bf LAI \u03b5\u03af\u03bd\u03b1\u03b9 \u03ad\u03bd\u03b1 \u03be\u03b5\u03c7\u03c9\u03c1\u03b9\u03c3\u03c4\u03cc \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd \u03bc\u03b5 \u03be\u03b5\u03c7\u03c9\u03c1\u03b9\u03c3\u03c4\u03ae \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1.<\/p>\n<h3>\u0398\u03b1 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03c3\u03b5\u03b9 \u03c4\u03bf Palip XR \u03c4\u03b7 \u03b3\u03bf\u03bd\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03ac \u03bc\u03bf\u03c5;<\/h3>\n<p>\u0397 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b1\u03ba\u03c4\u03af\u03bd\u03b7\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03b5\u03af\u03bb\u03b5\u03b9 \u03c4\u03b7 \u03b3\u03bf\u03bd\u03b9\u03bc\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03ac\u03bd\u03b4\u03c1\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03b3\u03c5\u03bd\u03b1\u03af\u03ba\u03b5\u03c2. \u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b5\u03c0\u03b9\u03c0\u03c4\u03ce\u03c3\u03b5\u03b9\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03c1\u03ad\u03c8\u03b9\u03bc\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03ae. \u0391\u03bd \u03b5\u03c0\u03b9\u03b8\u03c5\u03bc\u03b5\u03af\u03c4\u03b5 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7, \u03c3\u03c5\u03b6\u03b7\u03c4\u03ae\u03c3\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c3\u03b5 \u03b1\u03c1\u03b9\u03c0\u03b9\u03c0\u03c1\u03b1\u03b6\u03cc\u03bb\u03b7 \u03ae \u03ba\u03b5\u03c4\u03b9\u03b1\u03c0\u03af\u03bd\u03b7.<\/p>\n<h3>\u03a0\u03cc\u03c3\u03bf \u03c7\u03c1\u03cc\u03bd\u03bf \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03bd\u03b1 \u03b1\u03c1\u03c7\u03af\u03c3\u03b5\u03b9 \u03bd\u03b1 \u03b4\u03c1\u03b1 \u03c4\u03bf Palip XR;<\/h3>\n<p>\u039f\u03be\u03b5\u03af\u03b1 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03b1\u03c3\u03c4\u03ac\u03c4\u03c9\u03c3\u03b7 \u03b5\u03bd\u03c4\u03cc\u03c2 \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd. \u0391\u03bd\u03c4\u03b9\u03c8\u03c5\u03c7\u03c9\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b1 \u03b8\u03b5\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c3\u03b5 1\u20132 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2\u00b7 \u03c0\u03bb\u03ae\u03c1\u03b7\u03c2 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03b5 4\u20136 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2.<\/p>\n<h3>\u039c\u03c0\u03bf\u03c1\u03ce \u03bd\u03b1 \u03c3\u03c0\u03ac\u03c3\u03c9 \u03ae \u03bd\u03b1 \u03bb\u03b9\u03ce\u03c3\u03c9 \u03c4\u03bf \u03b4\u03b9\u03c3\u03ba\u03af\u03bf;<\/h3>\n<p>\u038c\u03c7\u03b9 \u2014 \u03c0\u03bf\u03c4\u03ad. \u0397 \u03c6\u03cc\u03c1\u03bc\u03bf\u03c5\u03bb\u03b1 OROS \u03bc\u03b5 \u03c9\u03c3\u03bc\u03c9\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03bb\u03af\u03b1 \u03b2\u03b1\u03c3\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03b5\u03b9 \u03ac\u03b8\u03b9\u03ba\u03c4\u03bf. \u0397 \u03c3\u03cd\u03bd\u03b8\u03bb\u03b9\u03c8\u03b7 \u03ae \u03b7 \u03b4\u03b9\u03b1\u03af\u03c1\u03b5\u03c3\u03b7 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03ad\u03c6\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b5\u03bb\u03b5\u03b3\u03c7\u03cc\u03bc\u03b5\u03bdo \u03b1\u03c0\u03bf\u03b4\u03ad\u03c3\u03bc\u03b5\u03c5\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03ba\u03b1\u03bb\u03b5\u03af \u03ac\u03bc\u03b5\u03c3\u03b7 \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2.<\/p>\n<h3>\u03a4\u03b9 \u03b3\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c4\u03bf\u03c5 Palip XR;<\/h3>\n<p>\u0397 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03bd\u03c4\u03c1\u03c9\u03bc\u03ad\u03bd\u03b7 \u03c3\u03c4\u03b9\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b5\u03c2 1\u20132 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2. \u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ad\u03c2 \u03b4\u03cc\u03c3\u03b5\u03b9\u03c2 \u03bf\u03b4\u03b7\u03b3\u03bf\u03cd\u03bd \u03ba\u03b1\u03bd\u03bf\u03bd\u03b9\u03ba\u03ac. \u0391\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03bd\u03ac\u03bb\u03c9\u03c3\u03b7 \u03b1\u03bb\u03ba\u03bf\u03cc\u03bb \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03bf\u03b4\u03ae\u03b3\u03b7\u03c3\u03b7.<\/p>\n<h3>\u0398\u03b1 \u03bc\u03b5 \u03ba\u03ac\u03bd\u03b5\u03b9 \u03c4\u03bf Palip XR \u03bd\u03b1 \u03c0\u03ac\u03c1\u03c9 \u03b2\u03ac\u03c1\u03bf\u03c2;<\/h3>\n<p>\u039d\u03b1\u03b9 \u2014 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 2\u20134 \u03ba\u03b9\u03bb\u03ac \u03c3\u03b5 6 \u03bc\u03ae\u03bd\u03b5\u03c2. \u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03bf\u03bb\u03b1\u03bd\u03b6\u03b1\u03c0\u03af\u03bd\u03b7 \u03ae \u03c4\u03b7\u03bd \u03ba\u03b5\u03c4\u03b9\u03b1\u03c0\u03af\u03bd\u03b7\u00b7 \u03c0\u03b1\u03c1\u03cc\u03bc\u03bf\u03b9\u03b1 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7.<\/p>\n<h3>\u039c\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b4\u03b9\u03b1\u03ba\u03bf\u03c0\u03b5\u03af \u03b1\u03c0\u03cc\u03c4\u03bf\u03bc\u03b1 \u03c4\u03bf Palip XR;<\/h3>\n<p>\u039c\u03b5\u03b9\u03ce\u03c3\u03c4\u03b5 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ac \u03c3\u03b5 2\u20134 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2. \u039f \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf\u03c2 \u03c5\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2 \u03c3\u03c4\u03b7 \u03c3\u03c7\u03b9\u03b6\u03bf\u03c6\u03c1\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c7\u03b9\u03b6\u03bf\u03b8\u03c5\u03bc\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03b5\u03af\u03bd\u03b1\u03b9 \u03b7 \u03ba\u03cd\u03c1\u03b9\u03b1 \u03b1\u03bd\u03b7\u03c3\u03c5\u03c7\u03af\u03b1.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03c4\u03bf Palip XR \u03b5\u03af\u03bd\u03b1\u03b9 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03c3\u03b5 \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7;<\/h3>\n<p>\u0397 \u03c0\u03b1\u03bb\u03b9\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03b1\u03c0\u03bf\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03ba\u03c5\u03c1\u03af\u03c9\u03c2 \u03bc\u03b5 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03ad\u03ba\u03ba\u03c1\u03b9\u03c3\u03b7 (75%) \u03c0\u03b1\u03c1\u03ac \u03bc\u03b5 \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03cc \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u2014 \u03b5\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bb\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03b1\u03c0\u03cc \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03bf\u03cd\u03bd \u03bc\u03b5 \u03c4\u03bf CYP. \u03a4\u03bf \u03c4\u03af\u03bc\u03b7\u03bc\u03b1: \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae \u03c4\u03b7\u03c2 \u03b4\u03cc\u03c3\u03b7\u03c2 \u03b3\u03b9\u03b1 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1, \u03b5\u03bd\u03ce \u03b7 \u03c1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7 \u03cc\u03c7\u03b9.<\/p>\n<h2>\u0386\u03bb\u03bb\u03b1 \u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03a8\u03c5\u03c7\u03b9\u03ba\u03ae\u03c2 \u03a5\u03b3\u03b5\u03af\u03b1\u03c2<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/aripicon\/\">Aripicon (\u0391\u03c1\u03b9\u03c0\u03b9\u03c0\u03c1\u03b1\u03b6\u03cc\u03bb\u03b7 \u2014 \u03bc\u03b5\u03c1\u03b9\u03ba\u03cc\u03c2 \u03b1\u03b3\u03c9\u03bd\u03b9\u03c3\u03c4\u03ae\u03c2 D2)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/olanzap\/\">Olanzap (\u039f\u03bb\u03b1\u03bd\u03b6\u03b1\u03c0\u03af\u03bd\u03b7 \u2014 \u03b9\u03c3\u03c7\u03c5\u03c1\u03cc \u03b1\u03bd\u03c4\u03b9\u03c8\u03c5\u03c7\u03c9\u03c3\u03b9\u03ba\u03cc)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/risdone\/\">Risdone (\u03a1\u03b9\u03c3\u03c0\u03b5\u03c1\u03b9\u03b4\u03cc\u03bd\u03b7)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/seroquit\/\">Seroquit (\u039a\u03bf\u03c5\u03b5\u03c4\u03b9\u03b1\u03c0\u03af\u03bd\u03b7 \u2014 \u03b4\u03b9\u03c0\u03bf\u03bb\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03b8\u03bb\u03b9\u03c8\u03b7)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/atlura\/\">Atlura (\u039b\u03bf\u03c5\u03c1\u03b1\u03c3\u03b9\u03b4\u03cc\u03bd\u03b7 \u2014 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac \u03bf\u03c5\u03b4\u03ad\u03c4\u03b5\u03c1\u03b7)<\/a><\/li>\n<\/ul>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:0.9em;\">\n<strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd.<\/strong> \u0391\u03c5\u03c4\u03ae \u03b7 \u03c3\u03b5\u03bb\u03af\u03b4\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c7\u03b1\u03c1\u03b1\u03ba\u03c4\u03ae\u03c1\u03b1 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c5\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c4\u03bf \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae\u03c2. \u0397 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c8\u03c5\u03c7\u03b9\u03ba\u03ae\u03c2 \u03c5\u03b3\u03b5\u03af\u03b1\u03c2 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03be\u03b5\u03ba\u03b9\u03bd\u03ac, \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03b5\u03af\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03cc\u03b6\u03b5\u03c4\u03b1\u03b9 \u03c5\u03c0\u03cc \u03c4\u03b7\u03bd \u03b5\u03c0\u03af\u03b2\u03bb\u03b5\u03c8\u03b7 \u03b5\u03bd\u03cc\u03c2 \u03ba\u03b1\u03c4\u03b1\u03be\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf\u03c5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03bf\u03cd. \u0395\u03ac\u03bd \u03b5\u03c3\u03b5\u03af\u03c2 \u03ae \u03ba\u03ac\u03c0\u03bf\u03b9\u03bf\u03c2 \u03c0\u03bf\u03c5 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03c4\u03b5 \u03b2\u03c1\u03af\u03c3\u03ba\u03b5\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03ba\u03c1\u03af\u03c3\u03b7 \u03b1\u03c5\u03c4\u03bf\u03ba\u03c4\u03bf\u03bd\u03af\u03b1\u03c2, \u03b5\u03c0\u03b9\u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03ae\u03c3\u03c4\u03b5 \u03b1\u03bc\u03ad\u03c3\u03c9\u03c2 \u03bc\u03b5 \u03c4\u03b9\u03c2 \u03c4\u03bf\u03c0\u03b9\u03ba\u03ad\u03c2 \u03c5\u03c0\u03b7\u03c1\u03b5\u03c3\u03af\u03b5\u03c2 \u03ad\u03ba\u03c4\u03b1\u03ba\u03c4\u03b7\u03c2 \u03b1\u03bd\u03ac\u03b3\u03ba\u03b7\u03c2 \u03ae \u03ba\u03b1\u03bb\u03ad\u03c3\u03c4\u03b5 \u03c4\u03b7 \u03b3\u03c1\u03b1\u03bc\u03bc\u03ae \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u03b1\u03c5\u03c4\u03bf\u03ba\u03c4\u03bf\u03bd\u03b9\u03ce\u03bd \u03c4\u03b7\u03c2 \u03c7\u03ce\u03c1\u03b1\u03c2 \u03c3\u03b1\u03c2 (\u0397\u03a0\u0391\/\u039a\u03b1\u03bd\u03b1\u03b4\u03ac\u03c2: 988; \u0397\u0392: Samaritans 116 123; \u03b4\u03b9\u03b5\u03b8\u03bd\u03ae\u03c2 \u03ba\u03b1\u03c4\u03ac\u03bb\u03bf\u03b3\u03bf\u03c2: <a href=\"https:\/\/findahelpline.com\/\" rel=\"nofollow noopener\" target=\"_blank\">findahelpline.com<\/a>).\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Palip XR (Paliperidone 3\/6\/9 mg XR) \u2014 \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf \u03b3\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03b7 \u03b1\u03c0\u03b5\u03bb\u03b5\u03c5\u03b8\u03ad\u03c1\u03c9\u03c3\u03b7, \u03ac\u03c4\u03c5\u03c0\u03bf \u03b1\u03bd\u03c4\u03b9\u03c8\u03c5\u03c7\u03c9\u03c3\u03b9\u03ba\u03cc \u03b3\u03b9\u03b1 \u03c3\u03c7\u03b9\u03b6\u03bf\u03c6\u03c1\u03ad\u03bd\u03b5\u03b9\u03b1 \u03ba\u03b1\u03b9 \u03c3\u03c7\u03b9\u03b6\u03bf\u03b1\u03c6\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae. \u039c\u03b9\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1, \u03b1\u03c0\u03bf\u03b2\u03ac\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b5\u03c6\u03c1\u03b9\u03ba\u03ac \u2014 \u03b4\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03bb\u03bb\u03ac\u03b6\u03bf\u03c5\u03bd \u03c4\u03bf CYP.<\/p>","protected":false},"featured_media":59955,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3906],"product_tag":[4774,4775],"class_list":{"0":"post-59954","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-mental-health-and-psychiatric-medications","9":"product_tag-palip-xr","10":"product_tag-paliperidone","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/59954","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=59954"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/59955"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=59954"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=59954"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=59954"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=59954"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}