{"id":60195,"date":"2024-02-28T06:37:55","date_gmt":"2024-02-28T06:37:55","guid":{"rendered":"https:\/\/medsname.com\/prazinec\/"},"modified":"2026-05-09T11:38:18","modified_gmt":"2026-05-09T11:38:18","slug":"prazinec","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/prazinec\/","title":{"rendered":"Prazinec"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Prazinec?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Prazinec<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>praziquantel 600&nbsp;mg<\/strong> \u03b1\u03c0\u03cc <strong>Sun Pharma<\/strong>. Praziquantel is the WHO Essential Medicine for <strong>schistosomiasis, intestinal flukes, liver flukes, and most cestodes including neurocysticercosis<\/strong>. Standard adult dose for schistosomiasis: <strong>40&nbsp;mg\/kg as a single dose<\/strong>; for tapeworm: 5&ndash;10&nbsp;mg\/kg single dose; for neurocysticercosis: 50&nbsp;mg\/kg\/day in 3 divided doses for 14&ndash;30 days under specialist supervision.<\/p>\n<\/div>\n<\/div>\n<p style=\"font-size:14px;margin:12px 0;\">\ud83d\udcd6 <strong>Full guide:<\/strong> <a href=\"\/el\/ivermectin-complete-guide\/\">Buy Ivermectin for Humans Online &#8212; Dosage, Safety &amp; What to Know<\/a><\/p>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase:<\/strong> \u2713 \u03a0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc <strong>WHO-GMP \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c5\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2<\/strong> \u00b7 \u2713 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u2713 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 \u2713 <strong>1,400+ \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/strong> \u03c3\u03c4\u03bf <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<h2 class=\"wp-block-heading\">What is Prazinec?<\/h2>\n<p><strong>Prazinec<\/strong> is praziquantel 600&nbsp;mg from <strong>Sun Pharma<\/strong>. Praziquantel is one of the most important drugs in tropical medicine &mdash; the global standard for schistosomiasis (which affects roughly 240 million people worldwide), and the agent of choice for most cestode and trematode infections. WHO mass-drug-administration programmes have used praziquantel to treat over a billion people since the 1990s.<\/p>\n<h2 class=\"wp-block-heading\">\u039c\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b4\u03c1\u03ac\u03c3\u03b7\u03c2<\/h2>\n<p>Praziquantel <strong>increases calcium permeability<\/strong> across the parasite tegument (outer covering), causing rapid sustained muscle contraction. This paralyses the worm and exposes its surface antigens to host immune attack &mdash; a one-two punch of pharmacological paralysis followed by immune-mediated killing. The mechanism explains why praziquantel works so well in immunocompetent patients and is somewhat less effective in heavily immunosuppressed hosts.<\/p>\n<p>Oral bioavailability is good (~80%) but first-pass hepatic metabolism is heavy &mdash; only about 25% reaches systemic circulation as active drug. Plasma half-life is 1&ndash;1.5 hours.<\/p>\n<h2 class=\"wp-block-heading\">Prazinec indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">\u0395\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">\u0394\u03cc\u03c3\u03b7<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Schedule<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Schistosomiasis (S. mansoni, S. haematobium, S. japonicum)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">40&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose (S. japonicum: 60&nbsp;mg\/kg)<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Intestinal tapeworm (Taenia saginata, T. solium)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">5&ndash;10&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Hymenolepis nana<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, repeat at 1 week<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Liver flukes (Clonorchis, Opisthorchis)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg TID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 1 day (75&nbsp;mg\/kg total)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Lung fluke (Paragonimus)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">25&nbsp;mg\/kg TID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 2 days<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Neurocysticercosis (specialist)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">50&nbsp;mg\/kg\/day in 3 doses<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 14&ndash;30 days WITH steroid cover<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Take with water or a soft drink during or shortly after a meal. Tablets have a bitter taste &mdash; do not chew. Children &gt; 4 years: same weight-based dosing applies.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Neurocysticercosis is a specialist diagnosis.<\/strong> Praziquantel for CNS cysticercosis must be given with concurrent corticosteroid (typically dexamethasone) to suppress the inflammatory response to dying cysts &mdash; otherwise raised intracranial pressure can be catastrophic. Imaging (MRI brain) is mandatory before treatment. Do not self-treat suspected neurocysticercosis.<\/div>\n<h2 class=\"wp-block-heading\">\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<ul>\n<li><strong>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> abdominal discomfort, nausea, malaise, headache, dizziness, drowsiness &mdash; usually within first 24&nbsp;hours, often related to dying parasites rather than the drug<\/li>\n<li><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong> urticaria, fever, transient eosinophilia rebound<\/li>\n<li><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1:<\/strong> bradycardia, transient transaminase rise<\/li>\n<li><strong>Neurocysticercosis-specific:<\/strong> headache, seizures, raised intracranial pressure as cysts die &mdash; the reason for steroid cover<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<ul>\n<li><strong>\u0399\u03c3\u03c7\u03c5\u03c1\u03bf\u03af \u03b5\u03c0\u03b1\u03b3\u03c9\u03b3\u03b5\u03af\u03c2 CYP3A4<\/strong> (rifampicin, carbamazepine, phenytoin, phenobarbital) &mdash; reduce praziquantel levels significantly; avoid combination or use alternative<\/li>\n<li><strong>\u0399\u03c3\u03c7\u03c5\u03c1\u03bf\u03af \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03b5\u03af\u03c2 CYP3A4<\/strong> (ketoconazole, ritonavir, cimetidine) &mdash; raise levels; reduce dose if combination unavoidable<\/li>\n<li><strong>Dexamethasone<\/strong> &mdash; reduces praziquantel levels by ~50%, but the combination is still required for neurocysticercosis (clinical effect retained)<\/li>\n<li><strong>Chloroquine<\/strong> &mdash; reduces praziquantel levels modestly<\/li>\n<li><strong>\u03a7\u03c5\u03bc\u03cc\u03c2 \u03b3\u03ba\u03c1\u03ad\u03b9\u03c0\u03c6\u03c1\u03bf\u03c5\u03c4<\/strong> &mdash; raises levels; avoid during treatment<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 &amp; \u03b8\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2.<\/strong> \u0397 \u03b1\u03bb\u03b2\u03b5\u03bd\u03b4\u03b1\u03b6\u03cc\u03bb\u03b7 \u03ba\u03b1\u03b9 \u03b7 \u03bc\u03b5\u03b2\u03b5\u03bd\u03b4\u03b1\u03b6\u03cc\u03bb\u03b7 \u0394\u0395\u039d \u03c3\u03c5\u03bd\u03b9\u03c3\u03c4\u03ce\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03c4\u03c1\u03af\u03bc\u03b7\u03bd\u03bf (\u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03c4\u03b5\u03c1\u03b1\u03c4\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7\u03c2 \u03b1\u03c0\u03cc \u03b6\u03ce\u03b1). \u0397 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bf\u03b4\u03b5\u03ba\u03c4\u03ae \u03c3\u03c4\u03bf 2\u03bf\/3\u03bf \u03c4\u03c1\u03af\u03bc\u03b7\u03bd\u03bf \u03b3\u03b9\u03b1 \u03bc\u03ad\u03c4\u03c1\u03b9\u03bf \u03ad\u03c9\u03c2 \u03b2\u03b1\u03c1\u03b9\u03ac \u03c6\u03bf\u03c1\u03c4\u03af\u03bf \u03c3\u03ba\u03c9\u03bb\u03ae\u03ba\u03c9\u03bd. \u03a4\u03b1 \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b9\u03b2\u03b5\u03c1\u03bc\u03b5\u03ba\u03c4\u03af\u03bd\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03b9\u03c3\u03bc\u03ad\u03bd\u03b1 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b8\u03b7\u03c3\u03c5\u03c7\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03b5 \u03c0\u03c1\u03bf\u03b3\u03c1\u03ac\u03bc\u03bc\u03b1\u03c4\u03b1 \u03bc\u03b1\u03b6\u03b9\u03ba\u03ae\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u03a0\u039f\u03a5\u00b7 \u03b1\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5 \u03c3\u03c4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03c4\u03c1\u03af\u03bc\u03b7\u03bd\u03bf \u03cc\u03c0\u03bf\u03c5 \u03c5\u03c0\u03ac\u03c1\u03c7\u03bf\u03c5\u03bd \u03b5\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2. \u0397 praziquantel \u03ba\u03b1\u03b9 \u03b7 pyrantel \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03c5\u03bc\u03b2\u03b1\u03c4\u03ad\u03c2 \u03bc\u03b5 \u03c4\u03b7\u03bd \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7.<\/div>\n<h2 class=\"wp-block-heading\">\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li>Hypersensitivity to praziquantel<\/li>\n<li>Ocular cysticercosis &mdash; treatment can destroy the eye; specialist surgical assessment first<\/li>\n<li>Children &lt; 4 years &mdash; safety not established<\/li>\n<li>\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>Store Prazinec below 30&deg;C in the original blister, protect from light and moisture.<\/p>\n<h3 class=\"wp-block-heading\">\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Prazinec is supplied from a <strong>\u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf \u03b1\u03c0\u03cc \u03c4\u03b7 WHO-GMP \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae<\/strong>, \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ac, \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03b5\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> \u2014 \u03c0\u03bf\u03c4\u03ad \u03b4\u03b5\u03bd \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03cd\u03bd\u03b5\u03c3\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03bf \u03ba\u03cc\u03c3\u03c4\u03bf\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03c7\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">How quickly does Prazinec work?<\/h3>\n<p>Schistosomes and most flukes are paralysed within hours. Egg shedding stops over the following 1&ndash;2 weeks. For schistosomiasis, urine or stool testing at 4&ndash;6 weeks confirms cure.<\/p>\n<h3 class=\"wp-block-heading\">Why take Prazinec with food?<\/h3>\n<p>Food increases bioavailability roughly 2-fold. For most indications this is helpful. Do not chew &mdash; the bitter taste is intense.<\/p>\n<h3 class=\"wp-block-heading\">Will I see worms in my stool after?<\/h3>\n<p>For tapeworm, expect partial passage of fragmented proglottids over the days following the dose &mdash; the worm is partly digested by host enzymes after praziquantel has done its job. For schistosomiasis the eggs are microscopic; you won&rsquo;t see worms.<\/p>\n<h3 class=\"wp-block-heading\">Is Prazinec safe in pregnancy?<\/h3>\n<p>WHO endorses praziquantel use in pregnancy where infection is symptomatic or the worm burden is significant. The first trimester is preferred to be avoided where alternatives exist. Consult a clinician for individualised guidance.<\/p>\n<h3 class=\"wp-block-heading\">Can children take Prazinec?<\/h3>\n<p>Yes from age 4 with the same weight-based dosing as adults. WHO mass-drug-administration programmes routinely treat school-age children for schistosomiasis with single-dose praziquantel.<\/p>\n<h3 class=\"wp-block-heading\">What if I have neurocysticercosis?<\/h3>\n<p>Treatment requires neurology supervision. MRI imaging, concurrent dexamethasone, and (for ocular involvement) ophthalmology assessment are mandatory. Self-treatment can be catastrophic &mdash; the brain inflammation from dying cysts can cause raised intracranial pressure.<\/p>\n<h3 class=\"wp-block-heading\">Does praziquantel treat ascaris or pinworm?<\/h3>\n<p>No. Praziquantel covers cestodes (tapeworms) and trematodes (flukes including schistosoma). For nematodes (ascaris, pinworm, hookworm, whipworm) use albendazole or mebendazole.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol after the dose?<\/h3>\n<p>Avoid alcohol on the day of treatment &mdash; it amplifies the dizziness and drowsiness common in the first 24&nbsp;hours.<\/p>\n<h3 class=\"wp-block-heading\">Why might Prazinec fail?<\/h3>\n<p>Most common reasons: under-dosing (especially in heavy patients), reinfection from continued exposure (re-entering schistosomiasis-endemic water bodies), or co-administration with strong CYP3A4 inducers (rifampicin, anticonvulsants) that reduce drug levels.<\/p>\n<h3 class=\"wp-block-heading\">Should I retest after treatment?<\/h3>\n<p>For schistosomiasis, retest with urine or stool at 4&ndash;6 weeks. For intestinal tapeworm, retest at 1 and 3 months. For neurocysticercosis, repeat MRI at 3&ndash;6 months under specialist guidance.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u0386\u03bb\u03bb\u03b1 \u0391\u03bd\u03c4\u03b9\u03c0\u03b1\u03c1\u03b1\u03c3\u03b9\u03c4\u03b9\u03ba\u03ac \u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/niclosig\/\">Niclosig (niclosamide 500 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/prazinec\/\">Prazinec (praziquantel 600 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/abd-400-albendazole\/\">ABD 400 (\u03b1\u03bb\u03b2\u03b5\u03bd\u03b4\u03b1\u03b6\u03cc\u03bb\u03b7 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/mebex\/\">Mebex (mebendazole)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tinvista\/\">Tinvista (tinidazole)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>\u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b1\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b5\u03c5\u03b8\u03c5\u03bd\u03ce\u03bd.<\/strong> \u0391\u03c5\u03c4\u03ae \u03b7 \u03c3\u03b5\u03bb\u03af\u03b4\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b3\u03b9\u03b1 \u03b5\u03ba\u03c0\u03b1\u03b9\u03b4\u03b5\u03c5\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c3\u03ba\u03bf\u03c0\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b5\u03bd \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03b8\u03b9\u03c3\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c0\u03b1\u03b3\u03b3\u03b5\u03bb\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae. \u03a3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03b5\u03c5\u03c4\u03b5\u03af\u03c4\u03b5 \u03ad\u03bd\u03b1\u03bd \u03ba\u03b1\u03c4\u03b1\u03c1\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03cc \u03b3\u03b9\u03b1\u03c4\u03c1\u03cc \u03c0\u03c1\u03b9\u03bd \u03be\u03b5\u03ba\u03b9\u03bd\u03ae\u03c3\u03b5\u03c4\u03b5 \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b1\u03bd\u03b8\u03b5\u03bb\u03bc\u03b9\u03bd\u03b8\u03b9\u03ba\u03cc, \u03b5\u03b9\u03b4\u03b9\u03ba\u03ac \u03b5\u03ac\u03bd \u03b5\u03af\u03c3\u03c4\u03b5 \u03ad\u03b3\u03ba\u03c5\u03bf\u03c2 \u03ae \u03b8\u03b7\u03bb\u03ac\u03b6\u03b5\u03c4\u03b5, \u03b1\u03bd\u03bf\u03c3\u03bf\u03ba\u03b1\u03c4\u03b5\u03c3\u03c4\u03b1\u03bb\u03bc\u03ad\u03bd\u03bf\u03b9, \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03cd\u03b5\u03c4\u03b5 \u03c0\u03b1\u03b9\u03b4\u03af \u03ba\u03ac\u03c4\u03c9 \u03c4\u03c9\u03bd 2 \u03b5\u03c4\u03ce\u03bd \u03ae \u03b5\u03ac\u03bd \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03b1\u03c1\u03b1\u03bc\u03ad\u03bd\u03bf\u03c5\u03bd \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bc\u03b9\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c0\u03bf\u03c1\u03b5\u03af\u03b1. \u0397 \u03b5\u03c9\u03c3\u03b9\u03bd\u03bf\u03c6\u03b9\u03bb\u03af\u03b1, \u03b7 \u03b1\u03c0\u03ce\u03bb\u03b5\u03b9\u03b1 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2, \u03bf \u03b5\u03c0\u03af\u03bc\u03bf\u03bd\u03bf\u03c2 \u03ba\u03bf\u03b9\u03bb\u03b9\u03b1\u03ba\u03cc\u03c2 \u03c0\u03cc\u03bd\u03bf\u03c2 \u03ae \u03c4\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b1\u03be\u03af\u03b4\u03b9\u03b1 \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03b1\u03be\u03b9\u03bf\u03bb\u03cc\u03b3\u03b7\u03c3\u03b7. \u039f\u03b9 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b1\u03c3\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b5\u03c2 (\u03bd\u03b5\u03c5\u03c1\u03bf\u03ba\u03c5\u03c3\u03c4\u03b9\u03ba\u03ad\u03c1\u03ba\u03c9\u03c3\u03b7, \u03c5\u03c0\u03b5\u03c1\u03bb\u03bf\u03af\u03bc\u03c9\u03be\u03b7 \u03c3\u03c4\u03c1\u03bf\u03b3\u03b3\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03ce\u03bd, \u03c3\u03c7\u03b9\u03c3\u03c4\u03bf\u03c3\u03c9\u03bc\u03af\u03b1\u03c3\u03b7 \u03bc\u03b5 \u03b5\u03bc\u03c0\u03bb\u03bf\u03ba\u03ae \u03bf\u03c1\u03b3\u03ac\u03bd\u03c9\u03bd) \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03c9\u03c0\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b5\u03b9\u03b4\u03b9\u03ba\u03cc.<\/div>","protected":false},"excerpt":{"rendered":"<p>Prazinec (praziquantel 600 mg, Sun Pharma) \u2014 WHO essential medicine for schistosomiasis, intestinal and liver flukes, and most cestodes. Standard 40 mg\/kg single dose for schistosomiasis.<\/p>","protected":false},"featured_media":60196,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3856],"product_tag":[4819,4596],"class_list":{"0":"post-60195","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-threadworm-treatment","9":"product_tag-prazinec","10":"product_tag-praziquantel","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/60195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=60195"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/60196"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=60195"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=60195"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=60195"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=60195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}