{"id":60463,"date":"2024-02-28T06:49:57","date_gmt":"2024-02-28T06:49:57","guid":{"rendered":"https:\/\/medsname.com\/maxtan\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"maxtan","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/maxtan\/","title":{"rendered":"Maxtan"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Maxtan?<\/h3>\n<p style=\"margin:0;\"><strong>Maxtan<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>5 mg \/ 10 mg rizatriptan oral tablet<\/strong> \u03b1\u03c0\u03cc \u03c4\u03b7 Sun Pharma \u2014 \u03ad\u03bd\u03b1 <strong>triptan-class abortive medication<\/strong> \u03b3\u03b9\u03b1 <strong>acute migraine attacks, with or without aura, in adults<\/strong>. rizatriptan is a second-generation selective 5-HT<sub>1B\/1D<\/sub> receptor agonist. Take <strong>at the first sign of migraine pain or aura<\/strong> &mdash; the earlier you dose, the higher the probability of full pain freedom. Onset of relief: <strong>30-60 minutes<\/strong>. May repeat after 2 hours if the migraine recurs (common &mdash; ~30% of responders have a 24-hour recurrence). <strong>Maximum 30 mg (max 3 doses; usually limited to 20 mg) in 24 hours<\/strong>. Triptans are <strong>contraindicated in coronary artery disease, previous myocardial infarction, uncontrolled hypertension, Prinzmetal angina, hemiplegic or basilar migraine, recent ergot or MAOI use, and severe hepatic impairment.<\/strong> Use triptans no more than <strong>10 days per month<\/strong> &mdash; over that threshold they cause a paradoxical medication-overuse headache. If you need acute treatment more often, add a preventive drug (<a href=\"https:\/\/medsbase.com\/el\/topicon\/\">\u03c4\u03bf\u03c0\u03b9\u03c1\u03b1\u03bc\u03ac\u03c4\u03b7<\/a>, <a href=\"https:\/\/medsbase.com\/el\/inderal\/\">\u03c0\u03c1\u03bf\u03c0\u03c1\u03b1\u03bd\u03cc\u03bb\u03bf\u03bb\u03b7<\/a>, <a href=\"https:\/\/medsbase.com\/el\/sibelium\/\">flunarizine<\/a>, <a href=\"https:\/\/medsbase.com\/el\/encorate\/\">valproate<\/a>).<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n<h2 class=\"wp-block-heading\">What Is Maxtan?<\/h2>\n<p>Maxtan is an oral oral tablet containing <strong>rizatriptan 5 mg \/ 10 mg<\/strong> from Sun Pharma, supplied in 10-180 tablet packs. Rizatriptan is a second-generation selective 5-HT<sub>1B\/1D<\/sub> receptor agonist &mdash; one of the core drug classes for the <strong>abortive (acute)<\/strong> treatment of migraine headache. Rizatriptan has the fastest oral-tablet onset among triptans (Tmax ~1 hour) and has the highest probability of 2-hour pain freedom in network meta-analysis (Cameron 2015). First choice when speed matters but nasal spray is not tolerated.<\/p>\n<h2 class=\"wp-block-heading\">How rizatriptan Works on Migraine<\/h2>\n<p>Migraine is driven by activation of the <strong>trigeminovascular system<\/strong> &mdash; trigeminal nerve fibres innervating dural and intracranial blood vessels release calcitonin gene-related peptide (CGRP), substance P, and neurokinin A, causing neurogenic inflammation, vasodilation, and central sensitisation.<\/p>\n<p>Triptans like rizatriptan bind selectively to <strong>5-HT<sub>1B<\/sub> receptors<\/strong> on cranial blood vessel smooth muscle (causing vasoconstriction of the dilated pain-producing arteries) and <strong>5-HT<sub>1D<\/sub> receptors<\/strong> on trigeminal nerve endings (inhibiting pro-inflammatory neuropeptide release). The combined vascular + neural action reverses the migraine attack, typically within 30-120 minutes.<\/p>\n<p>Onset from tablet route: <strong>30-60 minutes<\/strong>. Plasma peak: 1-1.5 hours. Elimination half-life: 2-3 hours.<\/p>\n<h2 class=\"wp-block-heading\">\u0395\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c2 \u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Acute treatment of migraine with or without aura<\/strong> in adults 18+ (primary indication)<\/li>\n<li><strong>Menstrual migraine<\/strong> &mdash; same dosing as regular migraine; some evidence for short-term prophylaxis around the menstrual window<\/li>\n<\/ul>\n<p><strong>Triptans are NOT for:<\/strong> tension-type headache (not effective), pain of other origin (sinus, musculoskeletal, trigeminal neuralgia), pre-emptive use without migraine pain, hemiplegic migraine, basilar migraine, ophthalmoplegic migraine, or migrainous infarction.<\/p>\n<h2 class=\"wp-block-heading\">Maxtan Dosage<\/h2>\n<ol>\n<li><strong>Take at first sign of migraine pain or aura.<\/strong> Triptans work best when taken early; taking them late in an established attack reduces response rates by ~30%.<\/li>\n<li>Swallow whole with water; food does not significantly affect absorption.<\/li>\n<li>If you respond but the headache returns within 24 hours, a second dose <strong>2 hours after the first<\/strong> is appropriate.<\/li>\n<li><strong>If the first dose does not work at all, a second dose for the same attack is unlikely to help.<\/strong> Switch to a rescue NSAID (naproxen 500 mg) or combination therapy.<\/li>\n<li>Maximum single dose: <strong>10 mg<\/strong>. Maximum in 24 hours: <strong>30 mg (max 3 doses; usually limited to 20 mg)<\/strong>.<\/li>\n<li><strong>Maximum 10 days per month<\/strong> across all triptans\/ergots\/combination analgesics to avoid medication-overuse headache.<\/li>\n<\/ol>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:18px 0;border-radius:4px;\">\n<strong>&#9888;&#65039; Medication-Overuse Headache Warning.<\/strong> Using acute migraine drugs too frequently causes a paradoxical rebound headache called <em>medication-overuse headache (MOH)<\/em>. Limits: <strong>triptans, ergots, or combination analgesics &le; 10 days per month<\/strong>; <strong>simple NSAIDs or paracetamol &le; 15 days per month<\/strong>. If you need acute treatment more often, you need a <strong>preventive drug<\/strong> (propranolol, topiramate, valproate, flunarizine, amitriptyline, or a CGRP antagonist).\n<\/div>\n<h2 class=\"wp-block-heading\">\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n<p><strong>Common (&gt;5%), usually transient, peaking in the first 30-60 minutes:<\/strong><\/p>\n<ul>\n<li><strong>Triptan sensations<\/strong> &mdash; tingling \/ warmth \/ pressure \/ heaviness in chest, neck, jaw, or limbs. Benign in most users and distinct from ischaemic chest pain, but indistinguishable on a clinical basis &mdash; see &#8220;Chest symptoms&#8221; below.<\/li>\n<li>Dizziness, drowsiness, fatigue<\/li>\n<li>Nausea (separate from migraine-related nausea)<\/li>\n<li>Flushing, warm sensations<\/li>\n<li>\u039e\u03b7\u03c1\u03bf\u03c3\u03c4\u03bf\u03bc\u03af\u03b1<\/li>\n<\/ul>\n<p><strong>\u0391\u03c3\u03c5\u03bd\u03ae\u03b8\u03b9\u03c3\u03c4\u03b5\u03c2:<\/strong> palpitations, anxiety, insomnia, muscle aches, mild hypertension.<\/p>\n<p><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b5\u03c2 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ad\u03c2:<\/strong> coronary vasospasm \/ angina \/ myocardial infarction (mostly in patients with unrecognised coronary disease), ischaemic colitis, stroke, serotonin syndrome (when combined with SSRIs\/SNRIs\/MAOIs &mdash; see Interactions).<\/p>\n<h3 class=\"wp-block-heading\">Chest Symptoms on a Triptan &mdash; What to Do<\/h3>\n<p>Chest tightness, pressure, or discomfort after a triptan dose is <strong>common and usually benign<\/strong> (triptan sensations). However, it is clinically indistinguishable from early angina. <strong>Rules:<\/strong><\/p>\n<ul>\n<li>First triptan dose &mdash; if new chest symptoms appear, get an ECG and cardiology review before the next triptan use. Established cardiac disease must be ruled out.<\/li>\n<li>Any chest pain associated with sweating, breathlessness, arm pain, or lasting &gt;20 minutes &mdash; treat as potential acute coronary syndrome; call emergency services.<\/li>\n<li>Benign triptan sensations typically settle within 20-30 minutes of the dose.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications &amp; Precautions<\/h2>\n<p><strong>Absolute contraindications (do NOT take Maxtan):<\/strong><\/p>\n<ul>\n<li>Ischaemic heart disease, history of myocardial infarction, known coronary artery disease<\/li>\n<li>Prinzmetal angina \/ variant angina<\/li>\n<li>Uncontrolled hypertension<\/li>\n<li>Previous stroke (ischaemic or haemorrhagic) or transient ischaemic attack<\/li>\n<li>Peripheral vascular disease<\/li>\n<li>Hemiplegic migraine, basilar migraine, ophthalmoplegic migraine, migrainous infarction<\/li>\n<li>\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 (Child-Pugh C)<\/li>\n<li>Use within <strong>24 hours<\/strong> of another triptan or any ergot alkaloid (dihydroergotamine, ergotamine, methysergide)<\/li>\n<li>Use within <strong>14 days<\/strong> of a monoamine oxidase inhibitor (phenelzine, tranylcypromine, moclobemide, selegiline) for zolmitriptan, rizatriptan, sumatriptan<\/li>\n<li>Hypersensitivity to triptans<\/li>\n<\/ul>\n<p><strong>Caution:<\/strong><\/p>\n<ul>\n<li>Cardiovascular risk factors (hypertension, hyperlipidaemia, smoking, diabetes, postmenopausal women, men &gt;40) &mdash; consider cardiac screening before first triptan use<\/li>\n<li>Moderate hepatic impairment &mdash; dose reduction may be needed<\/li>\n<li>Epilepsy or seizure threshold-lowering conditions<\/li>\n<li>Sulphonamide allergy (for sumatriptan, which has a sulphonyl group &mdash; cross-reaction rare but reported)<\/li>\n<\/ul>\n<p><strong>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7:<\/strong> sumatriptan has the most pregnancy-safety data (FDA Pregnancy Category C; registry data reassuring). Zolmitriptan and rizatriptan have less data. Generally acceptable if the migraine is severe and non-drug measures fail; discuss with your obstetrician.<\/p>\n<p><strong>\u0398\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2:<\/strong> small amounts in breast milk (~3-5% of maternal dose). Generally considered compatible; some advise &#8220;pump and dump&#8221; for 8 hours after a dose as extra caution.<\/p>\n<p><strong>\u03a0\u03b1\u03b9\u03b4\u03b9\u03ac:<\/strong> not routinely used in children under 12. Nasal sumatriptan and rizatriptan ODS have adolescent indications in some jurisdictions; use only under paediatric neurology guidance.<\/p>\n<p><strong>Elderly (over 65):<\/strong> cardiovascular risk is higher; many guidelines discourage first-time triptan use in patients over 65 without cardiac screening.<\/p>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<ul>\n<li><strong>Ergot alkaloids<\/strong> (dihydroergotamine, ergotamine, methysergide) &mdash; do not combine; prolonged vasospasm risk. Separate by at least 24 hours.<\/li>\n<li><strong>Other triptans<\/strong> &mdash; do not combine or use within 24 hours of each other.<\/li>\n<li><strong>MAOIs<\/strong> &mdash; contraindicated (see above).<\/li>\n<li><strong>SSRIs and SNRIs<\/strong> (fluoxetine, sertraline, citalopram, venlafaxine, duloxetine) &mdash; rare serotonin syndrome risk when combined with a triptan. FDA warned 2006 but ongoing real-world evidence suggests the risk is very low and the combination is often acceptable &mdash; monitor for serotonin syndrome symptoms (mental status changes, autonomic instability, neuromuscular hyperactivity).<\/li>\n<li><strong>\u03a0\u03c1\u03bf\u03c0\u03c1\u03b1\u03bd\u03bf\u03bb\u03cc\u03bb<\/strong> &mdash; increases rizatriptan plasma levels ~70%; reduce rizatriptan dose to 5 mg maximum per dose if the patient is also on propranolol.<\/li>\n<li><strong>\u039b\u03b9\u03b8\u03b9\u03bf<\/strong> &mdash; caution; theoretical serotonin syndrome risk.<\/li>\n<li><strong>\u0392\u03cc\u03c4\u03b1\u03bd\u03bf \u03c4\u03bf\u03c5 \u0391\u03b3\u03af\u03bf\u03c5 \u0399\u03c9\u03ac\u03bd\u03bd\u03b7<\/strong> &mdash; avoid; serotonin syndrome risk.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Maxtan vs Other Triptans<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Triptan<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Onset (oral)<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u0397\u03bc\u03b9\u03b6\u03c9\u03ae<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u039a\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03bf \u03b3\u03b9\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>Rizatriptan 10 mg<\/strong> (<a href=\"https:\/\/medsbase.com\/el\/maxtan\/\">Maxtan<\/a> \/ <a href=\"https:\/\/medsbase.com\/el\/rizatop\/\">Rizatop<\/a>)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~30-60 min<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">2-3 h<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Fastest oral onset; highest 2h pain-freedom rate<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>Sumatriptan 50-100 mg<\/strong> (<a href=\"https:\/\/medsbase.com\/el\/sumitop\/\">Sumitop<\/a> \/ <a href=\"https:\/\/medsbase.com\/el\/leemigran\/\">Leemigran<\/a>)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~30-60 min<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">2 h<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Most evidence; price-anchor of the class<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>Zolmitriptan 2.5-5 mg<\/strong> (<a href=\"https:\/\/medsbase.com\/el\/zolitas-ods\/\">Zolitas ODS<\/a> \/ <a href=\"https:\/\/medsbase.com\/el\/zolmist-nasal-spray\/\">Zolmist Nasal<\/a>)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~30-60 min (ODS), 10-15 min (nasal)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">3 h<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Good for migraine with heavy CNS symptoms; ODS useful with nausea<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Naratriptan 2.5 mg<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">2-4 h (slowest)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">6 h (longest)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Long-lasting attacks; lower recurrence rate<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Eletriptan 40-80 mg<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~30-60 min<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">4 h<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">High efficacy; second-line when others fail<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Sumatriptan-naproxen (<a href=\"https:\/\/medsbase.com\/el\/headset\/\">Headset<\/a>)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">~30-60 min<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a3\u03cd\u03bd\u03b8\u03b5\u03c4\u03bf<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Superior to either component alone in RCTs<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>If one triptan does not work, another might.<\/strong> The Lancet 2021 network meta-analysis on migraine shows ~25% of non-responders to one triptan will respond to a different triptan or a different formulation (e.g. nasal instead of oral). Try at least 2 triptans at adequate doses before concluding they don&#8217;t work for you.<\/p>\n<h2 class=\"wp-block-heading\">\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n<p>Store Maxtan below 25&deg;C in the original blister or bottle. Protect from light and moisture. Keep out of reach of children. Use before the expiry date.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">When should I take Maxtan?<\/h3>\n<p>At the very first sign of migraine pain or aura. Triptans are most effective when taken early &mdash; the sooner you dose, the higher the probability of complete pain freedom. Waiting to see if the headache will go away on its own reduces response rates by about 30%.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Maxtan for a tension headache or sinus pain?<\/h3>\n<p>No &mdash; triptans only work on migraine pain. They are not effective for tension headache, sinus pain, or non-migraine headache types. Many &#8220;sinus headaches&#8221; are actually migraines with nasal symptoms, so if your &#8220;sinus headache&#8221; responds to Maxtan, it is probably migraine; get a diagnostic review.<\/p>\n<h3 class=\"wp-block-heading\">What if Maxtan doesn&#8217;t work on an attack?<\/h3>\n<p>If the first dose has no effect after 2 hours, a second dose for the same attack is unlikely to help. Switch to a rescue NSAID (<a href=\"https:\/\/medsbase.com\/el\/naprosyn\/\">naproxen 500 mg<\/a>) or a different abortive strategy. For the next attack, try a different triptan or a different formulation (nasal spray, ODS); ~25% of non-responders to one triptan respond to another.<\/p>\n<h3 class=\"wp-block-heading\">How often can I use Maxtan?<\/h3>\n<p>\u039c\u03ad\u03b3\u03b9\u03c3\u03c4\u03bf <strong>10 days per month<\/strong> across all triptans, ergots, and combination analgesics combined. Over that threshold, triptans cause medication-overuse headache &mdash; a paradoxical rebound headache on top of the underlying migraine. If you are using acute medication more than 10 days\/month, you need a preventive drug (<a href=\"https:\/\/medsbase.com\/el\/topicon\/\">\u03c4\u03bf\u03c0\u03b9\u03c1\u03b1\u03bc\u03ac\u03c4\u03b7<\/a>, <a href=\"https:\/\/medsbase.com\/el\/inderal\/\">\u03c0\u03c1\u03bf\u03c0\u03c1\u03b1\u03bd\u03cc\u03bb\u03bf\u03bb\u03b7<\/a>, <a href=\"https:\/\/medsbase.com\/el\/sibelium\/\">flunarizine<\/a>, <a href=\"https:\/\/medsbase.com\/el\/encorate\/\">valproate<\/a>, amitriptyline, or a CGRP antagonist).<\/p>\n<h3 class=\"wp-block-heading\">I felt chest pressure after my first dose &mdash; should I stop?<\/h3>\n<p>Chest pressure, tightness, or warmth after a triptan is common (triptan sensations) and usually benign in patients without cardiac disease. But it is clinically indistinguishable from angina on symptoms alone. After a first episode of chest symptoms, get an ECG and cardiology review before your next triptan dose. If chest pain is severe, radiating, lasts &gt;20 minutes, or comes with sweating or breathlessness, treat as potential cardiac emergency.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Maxtan with my antidepressant?<\/h3>\n<p>Mostly yes, with caution. MAOIs (phenelzine, tranylcypromine) are <strong>absolute contraindications<\/strong> &mdash; do not combine. SSRIs and SNRIs (fluoxetine, sertraline, citalopram, venlafaxine, duloxetine) carry a small theoretical serotonin syndrome risk per a 2006 FDA advisory, but real-world data shows the risk is very low. Most neurologists allow the combination with monitoring. Avoid St John&#8217;s Wort.<\/p>\n<h3 class=\"wp-block-heading\">Is Maxtan safe in pregnancy?<\/h3>\n<p>Sumatriptan has the most pregnancy data; registry evidence is broadly reassuring (FDA Category C). Zolmitriptan and rizatriptan have less data. For severe migraine in pregnancy where non-drug measures fail, sumatriptan is the usual first choice. Discuss with your obstetrician before using any triptan in pregnancy.<\/p>\n<h3 class=\"wp-block-heading\">What are CGRP antagonists and do I need one instead of a triptan?<\/h3>\n<p>CGRP antagonists (erenumab, galcanezumab, fremanezumab, eptinezumab injectable monoclonals; rimegepant, ubrogepant, atogepant oral gepants) are a newer class that don&#8217;t cause vasoconstriction and are safe in patients with cardiovascular contraindications to triptans. They are typically reserved for: (a) patients who cannot take triptans due to CV disease, (b) patients who need preventive therapy beyond propranolol \/ topiramate \/ amitriptyline, or (c) patients with 4+ migraine days per month. Most people do well on triptans at much lower cost.<\/p>\n<h3 class=\"wp-block-heading\">Where can I buy Maxtan online?<\/h3>\n<p>You can buy Maxtan (rizatriptan 5 mg \/ 10 mg oral tablet, 10-180 tablet packs) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n<h2 class=\"wp-block-heading\">Related Migraine Treatments on MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/zolmist-nasal-spray\/\">Zolmist Nasal Spray &mdash; Zolmitriptan 5 mg (fast onset)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/zolitas-ods\/\">Zolitas ODS &mdash; Zolmitriptan 2.5\/5 mg oro-dispersible<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/rizatop\/\">Rizatop &mdash; Rizatriptan 10 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/rizact\/\">Rizact &mdash; Rizatriptan (Cipla)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/sumitop\/\">Sumitop &mdash; Sumatriptan 25\/50\/100 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/leemigran\/\">Leemigran &mdash; Sumatriptan 50\/100 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/anti-migraine\/\"><strong>Browse all Anti-Migraine Treatments<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 \u0399\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u0391\u03c0\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u0395\u03c5\u03b8\u03cd\u03bd\u03b7\u03c2.<\/strong> This page is for informational purposes only and does not replace medical advice from a qualified healthcare professional. Always consult your doctor before starting, changing, or stopping any migraine medication.<\/div>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 <strong>\u03a7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/inderal\/\">Inderal<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/montel\/\">Montel<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/etibo\/\">Etibo<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/lox-10-spray\/\">Lox 10% Spray<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/etoford\/\">Etoford<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Maxtan is rizatriptan 5 mg \/ 10 mg oral tablets from Sun Pharma \u2014 the fastest-onset oral triptan (peak plasma 1-1.5 h) and highest probability of 2-hour pain freedom in network meta-analysis (Cameron 2015). First choice when speed matters. Caution: dose limit 5 mg max if also on propranolol (70% level increase).<\/p>","protected":false},"featured_media":60464,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3553,3141,3223,3342,3554],"product_tag":[4867,3559],"class_list":{"0":"post-60463","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-migraine","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_cat-general-health","10":"product_cat-migraine-treatment","11":"product_tag-maxtan","12":"product_tag-rizatriptan","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/60463","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=60463"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/60464"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=60463"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=60463"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=60463"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=60463"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}