{"id":61394,"date":"2024-02-28T07:38:54","date_gmt":"2024-02-28T07:38:54","guid":{"rendered":"https:\/\/medsname.com\/epiduo-gel\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"epiduo-gel","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/epiduo-gel\/","title":{"rendered":"Epiduo Gel"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Epiduo Gel?<\/h3>\n<p style=\"margin:0;\"><strong>Epiduo Gel<\/strong> is a topical fixed-dose combination gel from Galderma containing <strong>adapalene 0.1% + benzoyl peroxide 2.5%<\/strong> &mdash; the gold-standard fixed-dose combination for moderate acne, combining a third-generation topical retinoid with the broad-spectrum antibacterial benzoyl peroxide. Apply a <strong>\u03bb\u03b5\u03c0\u03c4\u03ae \u03c3\u03c4\u03c1\u03ce\u03c3\u03b7 \u03bc\u03b9\u03b1 \u03c6\u03bf\u03c1\u03ac \u03ba\u03ac\u03b8\u03b5 \u03b2\u03c1\u03ac\u03b4\u03c5<\/strong> \u03c3\u03b5 \u03ba\u03b1\u03b8\u03b1\u03c1\u03cc \u03ba\u03b1\u03b9 \u03be\u03b7\u03c1\u03cc \u03b4\u03ad\u03c1\u03bc\u03b1. \u0391\u03c5\u03be\u03ae\u03c3\u03c4\u03b5 \u03c4\u03b7\u03bd \u03b1\u03bd\u03bf\u03c7\u03ae \u03c3\u03b5 2\u20134 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2. \u03a3\u03c5\u03bd\u03b4\u03c5\u03ac\u03c3\u03c4\u03b5 \u03bc\u03b5 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c7\u03c1\u03ae\u03c3\u03b7 SPF 30+. \u039f\u03c1\u03b1\u03c4\u03ae \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c3\u03b5 <strong>4\u20138 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong>; \u00b7 \u03bc\u03ad\u03b3\u03b9\u03c3\u03c4\u03b7 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b9\u03c2 12 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2. \u0394\u03b5\u03bd \u03c0\u03c1\u03bf\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03ae \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03ba\u03bf\u03bc\u03b2\u03bf\u03ba\u03c5\u03c3\u03c4\u03b9\u03ba\u03ae \u03b1\u03ba\u03bc\u03ae (\u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03c4\u03b5 <a href=\"https:\/\/medsbase.com\/el\/isotroin\/\">\u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 isotretinoin<\/a> \u03b1\u03bd\u03c4\u03af \u03b1\u03c5\u03c4\u03bf\u03cd).<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>\u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n<h2 class=\"wp-block-heading\">What Is Epiduo Gel?<\/h2>\n<p>Epiduo Gel is a topical combination gel from Galderma containing <strong>adapalene 0.1% + benzoyl peroxide 2.5%<\/strong>. the gold-standard fixed-dose combination for moderate acne, combining a third-generation topical retinoid with the broad-spectrum antibacterial benzoyl peroxide. The fixed-dose format means you get all the active ingredients in a single bedtime application instead of layering 2&ndash;3 separate products &mdash; significantly improving real-world adherence and reducing the chance of irritation from over-application.<\/p>\n<h2 class=\"wp-block-heading\">How Does Epiduo Gel Work?<\/h2>\n<p>Epiduo Gel targets multiple acne drivers simultaneously:<\/p>\n<ul>\n<li><strong>\u0391\u03b4\u03b1\u03c0\u03b1\u03bb\u03ad\u03bd\u03b7<\/strong> &mdash; a third-generation retinoid that binds RAR-&beta; and RAR-&gamma; receptors. Comedolytic, anti-inflammatory, and significantly less irritating than tretinoin.<\/li>\n<li><strong>Benzoyl peroxide (BPO)<\/strong> &mdash; oxidative antibacterial that kills <em>C. acnes<\/em> on contact. Unlike topical antibiotics, BPO does not produce bacterial resistance.<\/li>\n<li><strong>\u03a3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/strong> &mdash; targets all three drivers of inflammatory acne: comedone formation (adapalene), bacterial inflammation (BPO), and keratin plugging (both).<\/li>\n<\/ul>\n<p>\u039f \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc\u03c2 \u03c5\u03c0\u03b5\u03c1\u03c4\u03b5\u03c1\u03b5\u03af \u03bf\u03c0\u03bf\u03b9\u03b1\u03c3\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03bc\u03b5\u03bc\u03bf\u03bd\u03c9\u03bc\u03ad\u03bd\u03b7\u03c2 \u03bf\u03c5\u03c3\u03af\u03b1\u03c2 \u03c9\u03c2 \u03bc\u03bf\u03bd\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c3\u03b5 \u03c3\u03c5\u03b3\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2, \u03bc\u03b5 \u03c3\u03c5\u03b3\u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03b7 \u03b5\u03c1\u03b5\u03b8\u03b9\u03c3\u03bc\u03cc.<\/p>\n<h2 class=\"wp-block-heading\">\u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Mild to moderate acne vulgaris<\/strong> &mdash; especially mixed comedonal + inflammatory acne<\/li>\n<li><strong>First-line monotherapy<\/strong> for adolescent and adult acne (per AAD 2024 and EDF guidelines)<\/li>\n<li><strong>Maintenance after oral antibiotics or isotretinoin<\/strong> &mdash; prevents relapse<\/li>\n<li><strong>\u039c\u03ad\u03c4\u03c1\u03b9\u03b1 \u03b1\u03ba\u03bc\u03ae \u03c3\u03c4\u03bf\u03bd \u03ba\u03bf\u03c1\u03bc\u03cc<\/strong> (\u03c3\u03c4\u03ae\u03b8\u03bf\u03c2, \u03c0\u03bb\u03ac\u03c4\u03b7, \u03ce\u03bc\u03bf\u03c5\u03c2)<\/li>\n<\/ul>\n<p>Epiduo Gel is <strong>\u03b4\u03b5\u03bd<\/strong> \u03b3\u03b9\u03b1 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03ba\u03bf\u03bd\u03b4\u03c5\u03bb\u03c9\u03c4\u03b9\u03ba\u03ae \u03b1\u03ba\u03bc\u03ae (\u03c3\u03c4\u03bf\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b9\u03c3\u03bf\u03c4\u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u0390\u03bd\u03b7), \u03c1\u03bf\u03b4\u03cc\u03c7\u03c1\u03bf\u03c5 \u03ae \u03b5\u03b3\u03ba\u03b5\u03c6\u03b1\u03bb\u03b9\u03c4\u03b9\u03ba\u03cc \u03b4\u03ad\u03c1\u03bc\u03b1. \u0397 \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b1\u03ba\u03bc\u03ae \u03bc\u03b5 \u03bf\u03c5\u03bb\u03ad\u03c2 \u03b8\u03b1 \u03c0\u03c1\u03ad\u03c0\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03c0\u03b5\u03bc\u03c6\u03b8\u03b5\u03af \u03b3\u03b9\u03b1 <a href=\"https:\/\/medsbase.com\/el\/isotroin\/\">\u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 isotretinoin<\/a>.<\/p>\n<h2 class=\"wp-block-heading\">Epiduo Gel Dosage and How to Apply<\/h2>\n<p>Epiduo Gel comes in 30 g tube tubes containing adapalene 0.1% + benzoyl peroxide 2.5%.<\/p>\n<h3 class=\"wp-block-heading\">How to Apply Epiduo Gel Properly<\/h3>\n<ol>\n<li><strong>\u03a0\u03bb\u03cd\u03bd\u03b5\u03c4\u03b5 \u03b1\u03c0\u03b1\u03bb\u03ac<\/strong> \u03bc\u03b5 \u03ad\u03bd\u03b1 \u03ae\u03c0\u03b9\u03bf \u03ba\u03b1\u03b8\u03b1\u03c1\u03b9\u03c3\u03c4\u03b9\u03ba\u03cc \u03c7\u03c9\u03c1\u03af\u03c2 \u03b1\u03c6\u03c1\u03cc, \u03c3\u03c4\u03b7 \u03c3\u03c5\u03bd\u03ad\u03c7\u03b5\u03b9\u03b1 \u03c3\u03c4\u03b5\u03b3\u03bd\u03ce\u03c3\u03c4\u03b5 \u03bc\u03b5 \u03b5\u03bb\u03b1\u03c6\u03c1\u03ac \u03c0\u03b9\u03ad\u03c3\u03b5\u03b9\u03c2. <strong>\u03a0\u03b5\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c4\u03b5 20\u201330 \u03bb\u03b5\u03c0\u03c4\u03ac<\/strong> \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03c3\u03c4\u03b5\u03b3\u03bd\u03ce\u03c3\u03b5\u03b9 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1.<\/li>\n<li><strong>\u0395\u03c6\u03b1\u03c1\u03bc\u03cc\u03c3\u03c4\u03b5 \u03bc\u03b9\u03b1 \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03c4\u03bf \u03bc\u03ad\u03b3\u03b5\u03b8\u03bf\u03c2 \u03bc\u03c0\u03b9\u03b6\u03b5\u03bb\u03b9\u03bf\u03cd<\/strong> \u03c3\u03b5 \u03bf\u03bb\u03cc\u03ba\u03bb\u03b7\u03c1\u03b7 \u03c4\u03b7\u03bd \u03c0\u03bb\u03b7\u03b3\u03b5\u03af\u03c3\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae \u2014 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03c3\u03b5 \u03cc\u03bb\u03bf \u03c4\u03bf \u03c0\u03c1\u03cc\u03c3\u03c9\u03c0\u03bf. \u03a0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c4\u03b6\u03b5\u03bb \u03b4\u03b5\u03bd \u03b4\u03c1\u03b1 \u03c0\u03b9\u03bf \u03b3\u03c1\u03ae\u03b3\u03bf\u03c1\u03b1.<\/li>\n<li><strong>\u0391\u03c0\u03bb\u03ce\u03c3\u03c4\u03b5 \u03bb\u03b5\u03c0\u03c4\u03cc \u03c3\u03c4\u03c1\u03ce\u03bc\u03b1<\/strong> \u03c3\u03c4\u03bf \u03bc\u03ad\u03c4\u03c9\u03c0\u03bf, \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b1 \u03b4\u03cd\u03bf \u03bc\u03ac\u03b3\u03bf\u03c5\u03bb\u03b1, \u03c4\u03b7 \u03bc\u03cd\u03c4\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03c0\u03b7\u03b3\u03bf\u03cd\u03bd\u03b9. \u0391\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5 \u03c4\u03b1 \u03b2\u03bb\u03ad\u03c6\u03b1\u03c1\u03b1, \u03c4\u03b1 \u03c7\u03b5\u03af\u03bb\u03b7, \u03c4\u03b9\u03c2 \u03b3\u03c9\u03bd\u03af\u03b5\u03c2 \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03bf \u03b5\u03c3\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03b7\u03c2 \u03bc\u03cd\u03c4\u03b7\u03c2.<\/li>\n<li><strong>\u039c\u03af\u03b1 \u03c6\u03bf\u03c1\u03ac \u03ba\u03ac\u03b8\u03b5 \u03b2\u03c1\u03ac\u03b4\u03c5<\/strong> \u03c3\u03b5 \u03ad\u03bd\u03b1 \u03c0\u03c1\u03cc\u03b3\u03c1\u03b1\u03bc\u03bc\u03b1 \u03c3\u03c4\u03b1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7\u03c2: <strong>2\u20133 \u03b2\u03c1\u03ac\u03b4\u03b9\u03b1\/\u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1<\/strong> \u03c4\u03b9\u03c2 \u03c0\u03c1\u03ce\u03c4\u03b5\u03c2 2 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2, \u03bc\u03b5\u03c4\u03ac <strong>\u03bc\u03af\u03b1 \u03bc\u03ad\u03c1\u03b1 \u03bd\u03b1\u03b9 \u03bc\u03af\u03b1 \u03cc\u03c7\u03b9<\/strong>, \u03bc\u03b5\u03c4\u03ac <strong>\u03ba\u03ac\u03b8\u03b5 \u03b2\u03c1\u03ac\u03b4\u03c5<\/strong>.<\/li>\n<li><strong>\u03a0\u03c1\u03bf\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03ae \u03bc\u03ad\u03b8\u03bf\u03b4\u03bf\u03c2 sandwich<\/strong> for sensitive skin: moisturiser &rarr; wait 5 min &rarr; Epiduo Gel &rarr; wait 5 min &rarr; moisturiser.<\/li>\n<li><strong>\u0397\u03bc\u03b5\u03c1\u03ae\u03c3\u03b9\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b7 SPF 30+ \u03c4\u03bf \u03c0\u03c1\u03c9\u03af \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03bf\u03c7\u03c1\u03b5\u03c9\u03c4\u03b9\u03ba\u03ae.<\/strong> \u03a4\u03cc\u03c3\u03bf \u03b7 \u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u03b5\u03b9\u03b4\u03ae\u03c2 \u03bf\u03c5\u03c3\u03af\u03b1 (\u03b1\u03b4\u03b1\u03c0\u03b1\u03bb\u03ad\u03bd\u03b7) \u03cc\u03c3\u03bf \u03ba\u03b1\u03b9 \u03b7 \u03b2\u03ac\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b3\u03ad\u03bb\u03b7\u03c2 \u03b1\u03c5\u03be\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c5\u03c0\u03b5\u03c1\u03b9\u03ce\u03b4\u03b7 \u03b1\u03ba\u03c4\u03b9\u03bd\u03bf\u03b2\u03bf\u03bb\u03af\u03b1.<\/li>\n<li><strong>\u03a0\u03bb\u03cd\u03bd\u03b5\u03c4\u03b5 \u03c4\u03b1 \u03c7\u03ad\u03c1\u03b9\u03b1<\/strong> \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae.<\/li>\n<li><strong>Watch for fabric bleaching:<\/strong> use white pillowcases and white towels at night. BPO permanently bleaches dark fabric.<\/li>\n<li><strong>\u039a\u03b1\u03c4\u03b1\u03c0\u03bf\u03bd\u03b7\u03b8\u03b5\u03af\u03c4\u03b5.<\/strong> \u03a0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03bf\u03c1\u03b1\u03c4\u03ae \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03bd \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1 4\u20138; \u03bc\u03ad\u03b3\u03b9\u03c3\u03c4\u03b7 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c4\u03b7\u03bd \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1 12.<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Side Effects of Epiduo Gel<\/h2>\n<p><strong>\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 (\u03c7\u03b5\u03b9\u03c1\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03c4\u03b9\u03c2 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 1\u20134, \u03b5\u03be\u03bf\u03bc\u03b1\u03bb\u03cd\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac):<\/strong><\/p>\n<ul>\n<li>\u039e\u03b7\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2, \u03b1\u03c0\u03bf\u03bb\u03ad\u03c0\u03b9\u03c3\u03b7, \u03ae\u03c0\u03b9\u03b1 \u03b1\u03c0\u03bf\u03be\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7<\/li>\n<li>\u039a\u03ac\u03c8\u03b9\u03bc\u03bf \u03ae \u03c4\u03c3\u03bf\u03cd\u03be\u03b9\u03bc\u03bf \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7\u03bd \u03b5\u03c6\u03b1\u03c1\u03bc\u03bf\u03b3\u03ae<\/li>\n<li>\u0389\u03c0\u03b9\u03b1 \u03b5\u03c1\u03c5\u03b8\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1<\/li>\n<li>\u0391\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03bf\u03bd \u03ae\u03bb\u03b9\u03bf<\/li>\n<li>\u0391\u03c1\u03c7\u03b9\u03ba\u03ae \u03ad\u03be\u03b1\u03c1\u03c3\u03b7 \u03b1\u03ba\u03bc\u03ae\u03c2 \u03ae \u201c\u03ba\u03ac\u03b8\u03b1\u03c1\u03c3\u03b7\u201d \u03c4\u03b9\u03c2 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 2\u20136<\/li>\n<\/ul>\n<p><strong>\u039b\u03b9\u03b3\u03cc\u03c4\u03b5\u03c1\u03bf \u03c3\u03c5\u03c7\u03bd\u03ad\u03c2:<\/strong><\/p>\n<ul>\n<li>\u0394\u03b5\u03c1\u03bc\u03b1\u03c4\u03af\u03c4\u03b9\u03b4\u03b1 \u03b5\u03c0\u03b1\u03c6\u03ae\u03c2<\/li>\n<li>\u0395\u03ba\u03b6\u03b5\u03bc\u03b1\u03c4\u03ce\u03b4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/li>\n<li>\u03a0\u03c1\u03bf\u03c3\u03c9\u03c1\u03b9\u03bd\u03ae \u03c5\u03c0\u03b5\u03c1\u03c7\u03c1\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7 \u03c3\u03b5 \u03b4\u03ad\u03c1\u03bc\u03b1 Fitzpatrick III\u2013VI<\/li>\n<li>Severe peeling or eczema-like irritation if used too frequently<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u03a0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03ac\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03ba\u03b1\u03b9 \u03b8\u03b7\u03bb\u03b1\u03c3\u03bc\u03cc\u03c2:<\/strong> FDA Pregnancy Category C (adapalene); BPO is Category C in pregnancy. <strong>Not recommended in pregnancy.<\/strong> Switch to topical clindamycin or azelaic acid.<\/li>\n<li><strong>\u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03b5 UV. \u0397\u03bc\u03b5\u03c1\u03ae\u03c3\u03b9\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b5\u03c5\u03c1\u03ad\u03bf\u03c2 \u03c6\u03ac\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 SPF 30+ \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03bf\u03c7\u03c1\u03b5\u03c9\u03c4\u03b9\u03ba\u03ae. \u0391\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5 \u03c4\u03b1 \u03c3\u03bf\u03bb\u03ac\u03c1\u03b9\u03bf\u03c5\u03bc.<\/strong> \u0395\u03ba\u03b6\u03ad\u03bc\u03b1, \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03c1\u03bf\u03b4\u03cc\u03c7\u03c1\u03bf\u03b1, \u03c4\u03c1\u03b1\u03c5\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1:.<\/li>\n<li><strong>Eczema, severe rosacea, broken skin:<\/strong> \u03c0\u03b5\u03c1\u03b9\u03bc\u03ad\u03bd\u03b5\u03c4\u03b5 \u03bc\u03ad\u03c7\u03c1\u03b9 \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1 \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03bf\u03c5\u03bb\u03c9\u03b8\u03b5\u03af \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2.<\/li>\n<li><strong>\u0391\u03c0\u03bf\u03c4\u03c1\u03af\u03c7\u03c9\u03c3\u03b7 \u03bc\u03b5 \u03ba\u03b5\u03c1\u03af, \u03bc\u03b5 \u03bd\u03ae\u03bc\u03b1, \u03bb\u03ad\u03b9\u03b6\u03b5\u03c1 \u03ae \u03c7\u03b7\u03bc\u03b9\u03ba\u03ac \u03c0\u03b9\u03bb\u03af\u03bd\u03b3\u03ba:<\/strong> stop Epiduo Gel for 7&ndash;10 days before any of these procedures.<\/li>\n<li><strong>\u0386\u03bb\u03bb\u03b1 \u03c4\u03bf\u03c0\u03b9\u03ba\u03ac \u03b4\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ac \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03ac:<\/strong> \u03b1\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03bc\u03b5 \u03c3\u03ad\u03c1\u03bf\u03c5\u03b1 \u03c5\u03c8\u03b7\u03bb\u03ae\u03c2 \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c3\u03b5 AHA\/BHA, \u03c4\u03cc\u03bd\u03b5\u03c1 \u03bc\u03b5 \u03b1\u03bb\u03ba\u03bf\u03cc\u03bb\u03b7 \u03ae \u03ac\u03bb\u03bb\u03b1 \u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u03b5\u03b9\u03b4\u03ae.<\/li>\n<li><strong>Bleaching:<\/strong> BPO will <strong>permanently bleach fabrics<\/strong> &mdash; pillowcases, towels, dark clothing, hair. Apply at night to white pillowcases or after the morning routine has dried.<\/li>\n<li><strong>\u03a0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03ac\u03c4\u03c9 \u03c4\u03c9\u03bd 12 \u03b5\u03c4\u03ce\u03bd:<\/strong> \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c3\u03c4\u03b5 \u03bc\u03cc\u03bd\u03bf \u03c5\u03c0\u03cc \u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b2\u03bb\u03b5\u03c8\u03b7.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications &mdash; Who Should NOT Use Epiduo Gel<\/h2>\n<ul>\n<li>Known hypersensitivity to adapalene, benzoyl peroxide, or any component of the gel base<\/li>\n<li>\u0395\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7 \u03ae \u03c3\u03c7\u03b5\u03b4\u03b9\u03b1\u03c3\u03bc\u03cc\u03c2 \u03b5\u03b3\u03ba\u03c5\u03bc\u03bf\u03c3\u03cd\u03bd\u03b7\u03c2 (\u03bb\u03cc\u03b3\u03c9 \u03c4\u03b7\u03c2 \u03b1\u03b4\u03b1\u03c0\u03b1\u03bb\u03ad\u03bd\u03b7\u03c2)<\/li>\n<li>\u0395\u03bd\u03b5\u03c1\u03b3\u03cc \u03ad\u03ba\u03b6\u03b5\u03bc\u03b1, \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03c1\u03bf\u03b4\u03cc\u03c7\u03c1\u03bf\u03b1, \u03b4\u03b9\u03b1\u03bb\u03c5\u03bc\u03ad\u03bd\u03bf \u03ae \u03c5\u03b3\u03c1\u03cc \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03af\u03c4\u03b9\u03b4\u03b1 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b5\u03c1\u03b9\u03bf\u03c7\u03ae \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b5\u03af<\/li>\n<li>\u03a4\u03b1\u03c5\u03c4\u03cc\u03c7\u03c1\u03bf\u03bd\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b9\u03c3\u03bf\u03c4\u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u0390\u03bd\u03b7<\/li>\n<li>\u03a0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03ac\u03c4\u03c9 \u03c4\u03c9\u03bd 12 \u03b5\u03c4\u03ce\u03bd<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03ba\u03b1\u03b9 \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1\u03c2<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u03a3\u03c5\u03bd\u03b4\u03c5\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u0391\u03c0\u03bf\u03c4\u03ad\u03bb\u03b5\u03c3\u03bc\u03b1<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u03a4\u03b9 \u03bd\u03b1 \u03ba\u03ac\u03bd\u03b5\u03c4\u03b5<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0391\u03c0\u03bf\u03bb\u03cd\u03bc\u03b1\u03bd\u03c3\u03b7 \u03bc\u03b5 \u03c3\u03b1\u03bb\u03b9\u03ba\u03c5\u03bb\u03b9\u03ba\u03cc \u03bf\u03be\u03cd<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a3\u03c5\u03bc\u03b2\u03b1\u03c4\u03cc \u2014 \u03c3\u03c5\u03bc\u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03bf\u03af \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03af<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Use SA wash morning; Epiduo Gel at night.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u039f\u03c1\u03bf\u03cd\u03c2 \u03bc\u03b5 \u03c5\u03c8\u03b7\u03bb\u03ae \u03c0\u03b5\u03c1\u03b9\u03b5\u03ba\u03c4\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c3\u03b5 AHA\/BHA<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03c3\u03c5\u03c3\u03c3\u03c9\u03c1\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03b5\u03c1\u03b5\u03b8\u03b9\u03c3\u03bc\u03cc\u03c2<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0391\u03c0\u03bf\u03c6\u03cd\u03b3\u03b5\u03c4\u03b5 \u03c4\u03b7\u03bd \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03ae \u03c3\u03c4\u03af\u03b2\u03b1\u03c3\u03b7.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0392\u03b9\u03c4\u03b1\u03bc\u03af\u03bd\u03b7 C (L-\u03b1\u03c3\u03ba\u03bf\u03c1\u03b2\u03b9\u03ba\u03cc \u03bf\u03be\u03cd)<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a3\u03c5\u03bc\u03b2\u03b1\u03c4\u03cc<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Vitamin C in morning, Epiduo Gel at night.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Niacinamide<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0395\u03be\u03b1\u03b9\u03c1\u03b5\u03c4\u03b9\u03ba\u03cc\u03c2 \u03c3\u03cd\u03bd\u03c4\u03c1\u03bf\u03c6\u03bf\u03c2 \u2014 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03bf\u03bd \u03c6\u03c1\u03b1\u03b3\u03bc\u03cc<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Niacinamide morning, Epiduo Gel at night.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u0391\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b9\u03c3\u03bf\u03c4\u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u0390\u03bd\u03b7<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u03a0\u03bb\u03b5\u03bf\u03bd\u03b1\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u03b5\u03b9\u03b4\u03ce\u03bd \u2014 \u03cc\u03c7\u03b7 \u03b1\u03b8\u03c1\u03bf\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Stop Epiduo Gel during oral isotretinoin course.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Tretinoin or other topical retinoids<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Redundant with adapalene<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Use only one topical retinoid.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">\u039f\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2<\/h2>\n<ul>\n<li>\u03a6\u03c5\u03bb\u03ac\u03be\u03c4\u03b5 \u03c3\u03b5 \u03b8\u03b5\u03c1\u03bc\u03bf\u03ba\u03c1\u03b1\u03c3\u03af\u03b1 \u03b4\u03c9\u03bc\u03b1\u03c4\u03af\u03bf\u03c5, <strong>15\u201325\u00b0C<\/strong>. \u039c\u03b7\u03bd \u03c4\u03bf \u03c8\u03cd\u03c7\u03b5\u03c4\u03b5 \u03ae \u03c4\u03bf \u03ba\u03b1\u03c4\u03b1\u03c8\u03cd\u03c7\u03b5\u03c4\u03b5.<\/li>\n<li>\u039a\u03c1\u03b1\u03c4\u03ae\u03c3\u03c4\u03b5 \u03c4\u03bf \u03c3\u03c9\u03bb\u03ae\u03bd\u03b1 \u03c3\u03c6\u03b9\u03c7\u03c4\u03ac \u03ba\u03bb\u03b5\u03b9\u03c3\u03c4\u03cc.<\/li>\n<li>BPO is light-sensitive &mdash; keep tube in original carton, away from direct sunlight.<\/li>\n<li>\u0391\u03c0\u03bf\u03c1\u03c1\u03af\u03c8\u03c4\u03b5 6 \u03bc\u03ae\u03bd\u03b5\u03c2 \u03bc\u03b5\u03c4\u03ac \u03c4\u03bf \u03c0\u03c1\u03ce\u03c4\u03bf \u03ac\u03bd\u03bf\u03b9\u03b3\u03bc\u03b1.<\/li>\n<li>\u039a\u03c1\u03b1\u03c4\u03ae\u03c3\u03c4\u03b5 \u03bc\u03b1\u03ba\u03c1\u03b9\u03ac \u03b1\u03c0\u03cc \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03bf\u03b9\u03ba\u03af\u03b4\u03b9\u03b1.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u039b\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf MedsBase<\/h2>\n<p>\u0386\u03bb\u03bb\u03b5\u03c2 \u03c4\u03bf\u03c0\u03b9\u03ba\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03bf\u03c5 \u03c3\u03c4\u03cc\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03b1\u03ba\u03bc\u03ae\u03c2 \u03c0\u03bf\u03c5 \u03b4\u03b9\u03b1\u03c4\u03af\u03b8\u03b5\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf MedsBase:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/deriva-cms-gel\/\"><strong>Deriva CMS Gel (adapalene + clindamycin + moisturizer)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/clincitop-gel\/\"><strong>Clincitop Gel (clindamycin 1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/saslic-foaming-face-wash\/\"><strong>Saslic \u0391\u03c6\u03c1\u03ce\u03b4\u03b5\u03c2 \u03a0\u03bb\u03cd\u03c3\u03b9\u03bc\u03bf \u03a0\u03c1\u03bf\u03c3\u03ce\u03c0\u03bf\u03c5 (salicylic acid 2%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/retino-a-cream\/\"><strong>Retino-A \u039a\u03c1\u03ad\u03bc\u03b1 (tretinoin 0.025% \/ 0.05%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/retino-a-micro-gel\/\"><strong>Retino-A Micro Gel (tretinoin microspheres 0.04% \/ 0.1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tretiheal-cream\/\"><strong>Tretiheal \u039a\u03c1\u03ad\u03bc\u03b1 (tretinoin 0.025% \/ 0.05% \/ 0.1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tazret-forte-cream\/\"><strong>Tazret Forte \u039a\u03c1\u03ad\u03bc\u03b1 (tazarotene 0.1%)<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/isotroin\/\"><strong>Isotroin (oral isotretinoin 5\/10\/20\/30 mg)<\/strong><\/a><\/li>\n<\/ul>\n<p>\u03a7\u03c1\u03ae\u03c3\u03b9\u03bc\u03b7 \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7: <a href=\"https:\/\/medsbase.com\/el\/tretinoin-cream-vs-gel\/\">\u039a\u03c1\u03ad\u03bc\u03b1 \u03c4\u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u0390\u03bd\u03b7\u03c2 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03b3\u03ad\u03bb\u03b7\u03c2<\/a> \u00b7 <a href=\"https:\/\/medsbase.com\/el\/isotretinoin-vs-tretinoin\/\">\u0399\u03c3\u03bf\u03c4\u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u0390\u03bd\u03b7 \u03ad\u03bd\u03b1\u03bd\u03c4\u03b9 \u03c4\u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u0390\u03bd\u03b7\u03c2<\/a> \u00b7 <a href=\"https:\/\/medsbase.com\/el\/everything-you-want-to-know-about-acne\/\">\u038c\u03bb\u03b1 \u03cc\u03c3\u03b1 \u03b8\u03ad\u03bb\u03b5\u03c4\u03b5 \u03bd\u03b1 \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03b5\u03c4\u03b5 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03b1\u03ba\u03bc\u03ae<\/a>.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">Why is benzoyl peroxide important in Epiduo Gel?<\/h3>\n<p>Benzoyl peroxide kills <em>C. acnes<\/em> by oxidative damage that bacteria cannot develop resistance to &mdash; unlike clindamycin or erythromycin. It is the only acne ingredient that suppresses bacterial resistance development. The combination with adapalene means BPO blocks resistance even if you ever pair this with topical or oral antibiotics later.<\/p>\n<h3 class=\"wp-block-heading\">\u03a0\u03cc\u03c4\u03b5 \u03b8\u03b1 \u03b4\u03c9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1;<\/h3>\n<p>\u039f\u03c1\u03b1\u03c4\u03ae \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ce\u03b4\u03c9\u03bd \u03c0\u03b1\u03c0\u03bf\u03c5\u03bb\u03ce\u03bd \u03c3\u03b5 <strong>4\u20136 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong>. \u039c\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03ba\u03c9\u03bc\u03af\u03b4\u03c9\u03bd \u03c3\u03b5 <strong>8\u201312 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong>. \u039c\u03ad\u03b3\u03b9\u03c3\u03c4\u03b7 \u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7 \u03c3\u03c4\u03b9\u03c2 <strong>12 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong>. \u039f\u03b9 \u03c0\u03c1\u03ce\u03c4\u03b5\u03c2 2\u20136 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c3\u03c9\u03c1\u03b9\u03bd\u03ae \u03ad\u03be\u03b1\u03c1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03bc\u03ae\u03c2 \u2014 \u03bc\u03b7\u03bd \u03c3\u03c4\u03b1\u03bc\u03b1\u03c4\u03ae\u03c3\u03b5\u03c4\u03b5. \u0397 \u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd 4\u03b7 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b1.<\/p>\n<h3 class=\"wp-block-heading\">\u0395\u03af\u03bd\u03b1\u03b9 \u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae \u03b7 \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03ad\u03be\u03b1\u03c1\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03bc\u03ae\u03c2;<\/h3>\n<p>Yes &mdash; about 30&ndash;50% of patients have a temporary worsening in weeks 2&ndash;6 as adapalene surfaces existing microcomedones. Drop frequency to every other night until the flare settles, then resume nightly. Stopping for the flare is the most common reason Epiduo Gel &ldquo;does not work&rdquo;.<\/p>\n<h3 class=\"wp-block-heading\">Is Epiduo Gel safe in pregnancy?<\/h3>\n<p>FDA Pregnancy Category C (adapalene); BPO is Category C in pregnancy. <strong>Not recommended in pregnancy.<\/strong> Switch to topical clindamycin or azelaic acid.<\/p>\n<h3 class=\"wp-block-heading\">Will Epiduo Gel bleach my pillowcase?<\/h3>\n<p>Yes &mdash; permanently. Benzoyl peroxide bleaches dark fabric, hair colour, and dyed towels on contact. Use white pillowcases at night and white towels for face-drying while on this product.<\/p>\n<h3 class=\"wp-block-heading\">Do I really need sunscreen with Epiduo Gel?<\/h3>\n<p>\u039d\u03b1\u03b9 \u2014 \u03bc\u03b7 \u03b4\u03b9\u03b1\u03c0\u03c1\u03b1\u03b3\u03bc\u03b1\u03c4\u03b5\u03cd\u03c3\u03b9\u03bc\u03bf. \u03a4\u03bf \u03c3\u03c5\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03cc \u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u03b5\u03b9\u03b4\u03bf\u03cd\u03c2 \u03bb\u03b5\u03c0\u03c4\u03b1\u03af\u03bd\u03b5\u03b9 \u03c4\u03bf \u03b1\u03bd\u03ce\u03c4\u03b5\u03c1\u03bf \u03c3\u03c4\u03c1\u03ce\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b1\u03c0\u03cc UV \u03bc\u03b5\u03bb\u03b1\u03bd\u03b9\u03bd\u03bf\u03ba\u03ac\u03c0\u03b5\u03c2. \u03a7\u03c9\u03c1\u03af\u03c2 \u03ba\u03b1\u03b8\u03b7\u03bc\u03b5\u03c1\u03b9\u03bd\u03cc \u03b5\u03c5\u03c1\u03cd\u03c6\u03bb\u03b5\u03ba\u03c4\u03bf SPF 30+, \u03b1\u03bd\u03b1\u03bc\u03ad\u03bd\u03b5\u03c4\u03b5 \u03b7\u03bb\u03b9\u03b1\u03ba\u03cc \u03ad\u03b3\u03ba\u03b1\u03c5\u03bc\u03b1, \u03c5\u03c0\u03b5\u03c1\u03c7\u03c1\u03c9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03cc\u03c9\u03c1\u03b7 \u03b3\u03ae\u03c1\u03b1\u03bd\u03c3\u03b7 \u2014 \u03c4\u03bf \u03b1\u03bd\u03c4\u03af\u03b8\u03b5\u03c4\u03bf \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03b8\u03ad\u03bb\u03b1\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03b1\u03ba\u03bc\u03ae\u03c2.<\/p>\n<h3 class=\"wp-block-heading\">Can I wax, get laser hair removal, or have a chemical peel while on Epiduo Gel?<\/h3>\n<p>\u038c\u03c7\u03b9 \u2014 \u03ba\u03ac\u03bd\u03c4\u03b5 \u03c0\u03b1\u03cd\u03c3\u03b7 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03bb\u03ac\u03c7\u03b9\u03c3\u03c4\u03bf\u03bd 7\u201310 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03bf\u03c0\u03bf\u03b9\u03b1\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03b1\u03c0\u03bf\u03c4\u03c1\u03af\u03c7\u03c9\u03c3\u03b7 \u03bc\u03b5 \u03ba\u03b5\u03c1\u03af, \u03bd\u03ae\u03bc\u03b1, \u03bb\u03ad\u03b9\u03b6\u03b5\u03c1, \u03b4\u03b5\u03c1\u03bc\u03b1\u03c4\u03bf\u03be\u03cd\u03c3\u03b7, \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b5\u03bb\u03cc\u03bd\u03b1 \u03ae \u03c7\u03b7\u03bc\u03b9\u03ba\u03cc \u03be\u03cd\u03c3\u03b9\u03bc\u03bf. \u03a3\u03c5\u03bd\u03b5\u03c7\u03af\u03c3\u03c4\u03b5 \u03b1\u03c6\u03bf\u03cd \u03c4\u03bf \u03b4\u03ad\u03c1\u03bc\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03b1\u03bd\u03b1\u03c1\u03c1\u03ce\u03c3\u03b5\u03b9 \u03c0\u03bb\u03ae\u03c1\u03c9\u03c2 (\u03ac\u03bb\u03bb\u03b5\u03c2 5\u20137 \u03b7\u03bc\u03ad\u03c1\u03b5\u03c2).<\/p>\n<h3 class=\"wp-block-heading\">Epiduo Gel vs oral isotretinoin &mdash; which is right for me?<\/h3>\n<p>Epiduo Gel is for <strong>\u03ae\u03c0\u03b9\u03b1 \u03ad\u03c9\u03c2 \u03bc\u03ad\u03c4\u03c1\u03b9\u03b1 \u03b1\u03ba\u03bc\u03ae<\/strong>. <a href=\"https:\/\/medsbase.com\/el\/isotroin\/\">\u0397 \u03b9\u03c3\u03bf\u03c4\u03c1\u03b5\u03c4\u03b9\u03bd\u03bf\u0390\u03bd\u03b7 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c3\u03c4\u03cc\u03bc\u03b1 (Isotroin)<\/a> \u03b5\u03af\u03bd\u03b1\u03b9 \u03b3\u03b9\u03b1 <strong>\u03c3\u03bf\u03b2\u03b1\u03c1\u03ae \u03ba\u03bf\u03b9\u03bb\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03ba\u03bc\u03ae<\/strong>, scarring acne, or acne that has failed 6+ months of optimised topical therapy. Epiduo Gel will not clear severe cystic acne &mdash; do not waste 12 weeks finding out.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2<\/h3>\n<p>\u0386\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c3\u03b5 <strong>\u0398\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u0391\u03ba\u03bc\u03ae<\/strong> \u03c0\u03bf\u03c5 \u03bf\u03b9 \u03c0\u03b5\u03bb\u03ac\u03c4\u03b5\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03b6\u03bf\u03c5\u03bd \u03b5\u03c0\u03af\u03c3\u03b7\u03c2:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/tretiva\/\">Tretiva<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tazret-forte-cream\/\">Tazret Forte \u039a\u03c1\u03ad\u03bc\u03b1<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/yaz\/\">Yaz<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/melacare-forte-cream\/\">Melacare Forte Cream<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/tretizen\/\">Tretizen<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Clears acne<br \/>\n\u2705 Reduces inflammation<br \/>\n\u2705 Prevents new breakouts<br \/>\n\u2705 Improves skin texture<br \/>\n\u2705 Minimizes pore size<\/p>\n<p>Epiduo Gel contains Adapalene and Benzoyl Peroxide.<\/p>","protected":false},"featured_media":61395,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3215,3642,3141,3223,3342],"product_tag":[3644,5024,5025],"class_list":{"0":"post-61394","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-acne-treatment","7":"product_cat-beauty-skin-care","8":"product_cat-category-overview","9":"product_cat-chronic-conditions","10":"product_cat-general-health","11":"product_tag-adapalene","12":"product_tag-benzoyl-peroxide","13":"product_tag-epiduo-gel","15":"first","16":"instock","17":"shipping-taxable","18":"purchasable","19":"product-type-variable","20":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/61394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=61394"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/61395"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=61394"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=61394"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=61394"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=61394"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}