<\/p>\n
Biciphage 1000 SR<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03b9\u03b1 \u03bc\u03ac\u03c1\u03ba\u03b1 metformin hydrochloride<\/strong> (1000 mg SR), a first-line oral medicine for \u03b4\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 \u03c4\u03cd\u03c0\u03bf\u03c5 2<\/strong>. It works by reducing glucose production in the liver and improving how the body responds to insulin — it does not cause hypoglycaemia on its own<\/strong> and is weight-neutral or modestly weight-reducing. Metformin is the most widely prescribed antidiabetic worldwide, recommended as first-line therapy by ADA, EASD, NICE and IDF guidelines. Also used off-label for polycystic ovary syndrome (PCOS), prediabetes and gestational diabetes. Take with food to reduce GI upset. Most common side effects: diarrhoea, nausea, metallic taste — usually improve after 1–2 weeks or switching to SR. Avoid in eGFR < 30 mL\/min\/1.73 m²<\/strong>; dose-reduce if eGFR 30–45. Safe long-term; monitor vitamin B12 annually.<\/p>\n<\/div>\n \ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n \u03a4\u03b1 \u03b3\u03b5\u03bd\u03cc\u03c3\u03b7\u03bc\u03b1 \u03c6\u03ac\u03c1\u03bc\u03b1\u03ba\u03ac \u03bc\u03b1\u03c2 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ad\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd WHO-GMP \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b1\u03b3\u03ba\u03bf\u03c3\u03bc\u03af\u03c9\u03c2 \u03c3\u03b5 \u03b4\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae, \u03b1\u03c0\u03bb\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u2014 \u03c7\u03c9\u03c1\u03af\u03c2 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5 \u03c3\u03c4\u03bf \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c4\u03bf\u03c5 \u03b4\u03ad\u03bc\u03b1\u03c4\u03bf\u03c2. \u039f\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u03b4\u03c1\u03bf\u03bc\u03bf\u03bb\u03bf\u03b3\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03bc\u03ad\u03c3\u03c9 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf\u03c5 \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae (\u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03b5\u03ba\u03ba\u03b1\u03b8\u03ac\u03c1\u03b9\u03c3\u03b7\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03b5\u03c0\u03b5\u03be\u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ce\u03bd \u03bc\u03b5 \u03ba\u03ac\u03c1\u03c4\u03b1 \u2014 \u03c0\u03bf\u03c4\u03ad \u201cMedsBase\u201d \u03ae \u03bf\u03c0\u03bf\u03b9\u03bf\u03b4\u03ae\u03c0\u03bf\u03c4\u03b5 \u03cc\u03bd\u03bf\u03bc\u03b1 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5). \u0393\u03af\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b5\u03ba\u03c4\u03ad\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03bb\u03b7\u03c1\u03c9\u03bc\u03ad\u03c2 \u03bc\u03b5 \u03ba\u03c1\u03c5\u03c0\u03c4\u03bf\u03bd\u03bf\u03bc\u03af\u03c3\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03b1\u03c0\u03b5\u03b6\u03b9\u03ba\u03ae \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac SEPA. \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u0395\u03be\u03b1\u03c3\u03c6\u03b1\u03bb\u03af\u03c3\u03b5\u03ce\u03c2 \u03bc\u03b1\u03c2.<\/p>\n Biciphage 1000 SR is an oral antidiabetic medicine containing metformin hydrochloride<\/strong> (1000 mg SR), manufactured by WHO-GMP certified manufacturer. Sustained-release (SR) formulation — releases metformin gradually over 8–10 hours, reducing GI side effects and allowing once-daily dosing. It is prescribed for adults and children 10 years and older with type 2 diabetes mellitus, typically alongside diet and exercise. Available in packs of 30, 60, 90 or 180 tablets.<\/p>\n Metformin belongs to the biguanide class<\/strong> and has been in clinical use since 1957. It is the single most prescribed diabetes medicine in the world and is on the WHO Essential Medicines List.<\/p>\n Metformin has three overlapping mechanisms that together lower blood glucose without causing hypoglycaemia in non-diabetic states:<\/p>\n Metformin typically lowers HbA1c by 1,0\u20131,5 \u03c0\u03bf\u03c3\u03bf\u03c3\u03c4\u03b9\u03b1\u03af\u03b5\u03c2 \u03bc\u03bf\u03bd\u03ac\u03b4\u03b5\u03c2<\/strong> as monotherapy. It is weight-neutral or results in modest weight loss (2–3 kg on average) and has favourable cardiovascular outcomes (UKPDS, long-term follow-up).<\/p>\n Metformin SR dosing:<\/strong> Usual starting dose is 500 mg once daily with the evening meal. Titrate up in 500 mg increments weekly if tolerated. Maximum dose is 2,000 mg once daily (or split into two doses of 1,000 mg twice daily if GI upset). Always take Biciphage 1000 SR with or immediately after food<\/strong> — this dramatically reduces the risk of nausea and diarrhoea.<\/p>\n Metformin is generally well-tolerated. The most common side effects (affecting 10–25% of users, usually in the first 2 weeks) are:<\/p>\n These are usually mild and self-limiting. Switching to an SR formulation or taking with larger meals resolves GI symptoms in most cases.<\/p>\n \u03a3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ac:<\/strong><\/p>\n \u03a3\u03b5 pregnancy<\/strong>, metformin is widely used for gestational diabetes and PCOS and has a strong safety record; discuss with your obstetrician. It passes into breast milk in tiny amounts and is generally considered compatible with breastfeeding.<\/p>\n Store Biciphage 1000 SR below 25°C in a dry place, in the original blister. Keep out of reach of children.<\/p>\n Yes. Biciphage 1000 SR contains the same active ingredient (metformin hydrochloride) as the originator brand Glucophage and every other metformin generic. Bioequivalence is required by regulatory authorities, so clinical effect is the same at the same dose.<\/p>\n Metformin produces modest weight loss (typically 2–3 kg over 6–12 months) in people with type 2 diabetes or insulin resistance. It is not a weight-loss drug in non-diabetic adults — effects are small and most studies show weight loss only in those with elevated insulin levels or PCOS.<\/p>\n Yes — metformin is widely used off-label for polycystic ovary syndrome to improve insulin sensitivity, restore ovulation, and reduce androgen symptoms. Typical dose is 1,500–2,000 mg\/day.<\/p>\n Not on its own. Metformin does not stimulate insulin release, so it does not cause hypoglycaemia as monotherapy. Low blood sugar becomes a concern only when metformin is combined with a sulfonylurea, meglitinide, or insulin.<\/p>\n Fasting glucose usually falls within 1–2 weeks. Maximal HbA1c effect is seen at 2–3 months. If HbA1c has not fallen by 0.5% or more after 3 months at maximum tolerated dose, additional therapy is usually added.<\/p>\n Moderate alcohol (1–2 drinks per day) is generally safe. Heavy or binge drinking should be avoided — it increases lactic acidosis risk and can cause hypoglycaemia, especially without food.<\/p>\n You can order Biciphage 1000 SR (1000 mg SR) from MedsBase in packs of 30, 60, 90 or 180 tablets. We ship worldwide, with discreet packaging and genuine WHO-GMP certified manufacturer stock.<\/p>\n Biciphage 1000 SR users often add a sulfonylurea step-up tablet once metformin monotherapy is no longer controlling HbA1c; for the bundled first-line + step-up regimen see our \u03a3\u03c4\u03b1\u03c1\u03c4\u03b5\u03c1 \u03a0\u03b1\u03ba\u03ad\u03c4\u03bf \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7 (Glycomet SR 1000 mg + Glycomet-GP)<\/a> with both tiers shipped together.<\/p>\n Patients managed on Biciphage 1000 SR<\/a> who require flexible SR dosing \u2014 including 250 mg, 500 mg, or 850 mg strengths \u2014 may consider Glycomet SR (metformin hydrochloride 250\u20131000 mg SR)<\/a> as a WHO-GMP-certified alternative offering the same extended-release metformin backbone across a broader strength range.<\/p>\n <\/p>\n \u2705 Lowers blood sugar Biciphage 1000 SR contains \u039c\u03b5\u03c4\u03c6\u03bf\u03c1\u03bc\u03af\u03bd\u03b7<\/strong>.<\/p>","protected":false},"featured_media":64535,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3230,3231],"product_tag":[5310,3255],"class_list":{"0":"post-64534","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-diabetes","7":"product_cat-diabetes-medication","8":"product_tag-biciphage","9":"product_tag-metformin","11":"first","12":"instock","13":"shipping-taxable","14":"purchasable","15":"product-type-variable","16":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/64534","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=64534"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/64535"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=64534"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=64534"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=64534"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=64534"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n
What Is Biciphage 1000 SR?<\/h2>\n
How Does Biciphage 1000 SR Work?<\/h2>\n
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\u0394\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03a7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7<\/h2>\n
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\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b5\u03c2<\/h2>\n
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\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n
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Who Should Not Take Biciphage 1000 SR?<\/h2>\n
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\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/h2>\n
\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n
Is Biciphage 1000 SR the same as metformin?<\/h3>\n
Will Biciphage 1000 SR help me lose weight?<\/h3>\n
Can I take Biciphage 1000 SR for PCOS?<\/h3>\n
Does Biciphage 1000 SR cause hypoglycaemia (low blood sugar)?<\/h3>\n
How long does Biciphage 1000 SR take to work?<\/h3>\n
Can I drink alcohol while taking Biciphage 1000 SR?<\/h3>\n
Where can I buy Biciphage 1000 SR online?<\/h3>\n
\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ac \u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03b1 \u03b3\u03b9\u03b1 \u0394\u03b9\u03b1\u03b2\u03ae\u03c4\u03b7<\/h2>\n
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\n\u2705 Manages type 2 diabetes
\n\u2705 \u03a5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c7\u03b5\u03af\u03c1\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03b2\u03ac\u03c1\u03bf\u03c5\u03c2
\n\u2705 \u0392\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03c5\u03b1\u03b9\u03c3\u03b8\u03b7\u03c3\u03af\u03b1 \u03c3\u03c4\u03b7\u03bd \u03b9\u03bd\u03c3\u03bf\u03c5\u03bb\u03af\u03bd\u03b7
\n\u2705 Reduces risk of complications<\/p>\n