{"id":68897,"date":"2026-03-02T18:06:52","date_gmt":"2026-03-02T18:06:52","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&#038;p=68897"},"modified":"2026-05-21T07:14:11","modified_gmt":"2026-05-21T07:14:11","slug":"ipamorelin","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/ipamorelin\/","title":{"rendered":"\u0399\u03c0\u03b1\u03bc\u03bf\u03c1\u03b5\u03bb\u03af\u03bd\u03b7"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background: #fff8e1; border-left: 4px solid #f5a623; padding: 18px 22px; margin: 18px 0; border-radius: 4px;\">\n<h3 style=\"margin: 0 0 8px 0; font-size: 16px; color: #1a4a6b;\">Quick Answer \u2014 What is Ipamorelin?<\/h3>\n<p style=\"margin: 0;\"><strong>\u0399\u03c0\u03b1\u03bc\u03bf\u03c1\u03b5\u03bb\u03af\u03bd\u03b7<\/strong> is a synthetic pentapeptide growth-hormone secretagogue that binds the ghrelin receptor (GHS-R1a) to trigger pulsatile GH release <strong>\u03c7\u03c9\u03c1\u03af\u03c2<\/strong> raising cortisol or prolactin \u2014 a selectivity that distinguishes it from older GHRPs. In research it is frequently stacked with CJC-1295 to amplify GH pulse amplitude. Supplied in 2\u00a0mg to 10\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background: #f4f8fb; border: 1px solid #d8e3eb; padding: 12px 16px; margin: 16px 0; border-radius: 4px; font-size: 14px;\"><strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u0395\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03bb\u03c5\u03bf\u03c6\u03b9\u03bb\u03b9\u03c9\u03bc\u03ad\u03bd\u03b1 \u03c0\u03b5\u03c0\u03c4\u03af\u03b4\u03b9\u03b1 \u00b7 HPLC \u03ba\u03b1\u03b8\u03b1\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1 \u226599% (COA \u03ba\u03b1\u03c4\u03cc\u03c0\u03b9\u03bd \u03b1\u03b9\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2) \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03c3\u03b5 \u03b8\u03b5\u03c1\u03bc\u03bf\u03ba\u03c1\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03af\u03c9\u03bd \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size: 14px; color: #444; margin: 8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<table class=\"medsbase-spec-table\" style=\"width: 100%; border-collapse: collapse; margin: 18px 0; font-size: 14px;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 8px 12px; text-align: left; width: 30%;\">\u03a0\u03c1\u03bf\u03b4\u03b9\u03b1\u03b3\u03c1\u03b1\u03c6\u03ae<\/th>\n<th style=\"padding: 8px 12px; text-align: left;\">\u039b\u03b5\u03c0\u03c4\u03bf\u03bc\u03ad\u03c1\u03b5\u03b9\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u0391\u03c1\u03b9\u03b8\u03bc\u03cc\u03c2 CAS<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">170851-70-4<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u039c\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc\u03c2 \u03a4\u03cd\u03c0\u03bf\u03c2<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">C<sub>38<\/sub>H<sub>49<\/sub>N<sub>9<\/sub>O<sub>5<\/sub><\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u039c\u03bf\u03c1\u03b9\u03b1\u03ba\u03cc \u0392\u03ac\u03c1\u03bf\u03c2<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">711.86 Da<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u0391\u03ba\u03bf\u03bb\u03bf\u03c5\u03b8\u03af\u03b1<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">Aib-His-D-2-Nal-D-Phe-Lys-NH<sub>2<\/sub><\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u039c\u03bf\u03c1\u03c6\u03ae<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u03a5\u03b1\u03bb\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03b7 \u03c3\u03ba\u03cc\u03bd\u03b7 (\u03ae \u03cc\u03c0\u03c9\u03c2 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03c4\u03b1\u03b9)<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u039a\u03b1\u03b8\u03b1\u03c1\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u226599% (HPLC \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03bf, COA \u03ba\u03b1\u03c4\u03cc\u03c0\u03b9\u03bd \u03b1\u03b9\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2)<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u039b\u03c5\u03bf\u03c6\u03b9\u03bb\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf: 2\u20138 \u00b0C (\u03c8\u03c5\u03b3\u03b5\u03af\u03bf) \u03b3\u03b9\u03b1 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b9\u03ba\u03cc \u03b1\u03c0\u03cc\u03b8\u03b5\u03bc\u03b1\u00b7 \u221220 \u00b0C \u03b3\u03b9\u03b1 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c0\u03c1\u03cc\u03b8\u03b5\u03c3\u03bc\u03b7 \u03b1\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7 \u03b1\u03bd\u03bf\u03b9\u03c7\u03c4\u03ce\u03bd \u03c6\u03b9\u03b1\u03bb\u03ce\u03bd. \u0391\u03bd\u03b1\u03c3\u03c5\u03bd\u03c4\u03b5\u03b8\u03b5\u03b9\u03bc\u03ad\u03bd\u03bf: 2\u20138 \u00b0C, \u03c7\u03c1\u03ae\u03c3\u03b7 \u03b5\u03bd\u03c4\u03cc\u03c2 ~30 \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd. \u03a0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1 \u03b1\u03c0\u03cc \u03c4\u03bf \u03c6\u03c9\u03c2. \u039c\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03c8\u03cd\u03c7\u03b5\u03c4\u03b5-\u03b1\u03c0\u03bf\u03c8\u03cd\u03c7\u03b5\u03c4\u03b5 \u03c4\u03bf \u03b1\u03bd\u03b1\u03c3\u03c5\u03bd\u03c4\u03b5\u03b8\u03b5\u03b9\u03bc\u03ad\u03bd\u03bf \u03b4\u03b9\u03ac\u03bb\u03c5\u03bc\u03b1.<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u0394\u03b9\u03b1\u03bb\u03c5\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u0392\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03bf\u03c3\u03c4\u03b1\u03c4\u03b9\u03ba\u03cc \u03bd\u03b5\u03c1\u03cc (\u03c0\u03c1\u03bf\u03c4\u03b5\u03af\u03bd\u03b5\u03c4\u03b1\u03b9) \u03ae \u03c3\u03c4\u03b5\u03b9\u03c1\u03c9\u03bc\u03ad\u03bd\u03bf \u03bd\u03b5\u03c1\u03cc \u03b3\u03b9\u03b1 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b1 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ac \u03b4\u03b9\u03b1\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c7\u03c1\u03ae\u03c3\u03b7\u03c2<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u0395\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03a7\u03c1\u03ae\u03c3\u03b7<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u039c\u03cc\u03bd\u03bf \u03b3\u03b9\u03b1 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1. \u0394\u03b5\u03bd \u03c0\u03c1\u03bf\u03bf\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ae \u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c3\u03b5 \u03b1\u03bd\u03b8\u03c1\u03ce\u03c0\u03bf\u03c5\u03c2 \u03ae \u03b6\u03ce\u03b1.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><!-- \/medsbase-tldr-answer --><\/p>\n<h2>What Is Ipamorelin?<\/h2>\n<p><strong>\u0399\u03c0\u03b1\u03bc\u03bf\u03c1\u03b5\u03bb\u03af\u03bd\u03b7<\/strong> is a synthetic pentapeptide belonging to the growth-hormone-releasing peptide (GHRP) family. Developed by Novo Nordisk in the 1990s and first characterised by Raun et al. (Eur J Endocrinol, 1998), it is classified as a <strong>growth hormone secretagogue<\/strong> \u2014 a compound that triggers endogenous GH release by activating the ghrelin receptor (GHS-R1a) on pituitary somatotropes.<\/p>\n<p>Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH<sub>2<\/sub>. Molecular weight approximately 711.9\u00a0Da. Unlike earlier GHRPs (GHRP-2, GHRP-6, hexarelin), ipamorelin is remarkable for its <strong>clean hormonal selectivity<\/strong> \u2014 it releases GH without meaningfully raising cortisol, prolactin, or ACTH. This selectivity is why ipamorelin has become the most-studied GHRP of the 21st century. It is supplied as a high-purity lyophilized powder for reconstitution with bacteriostatic water. Ipamorelin is <strong>for laboratory research use only<\/strong> and is not intended for human or veterinary diagnosis or therapy. For mechanism, published research, and stacking protocols, see our <a href=\"https:\/\/medsbase.com\/el\/ipamorelin-cjc-1295-stack-guide\/\">Ipamorelin &amp; CJC-1295 research guide<\/a>.<\/p>\n<h2>Mechanism of Action \u2014 Selective Ghrelin-Receptor Agonism<\/h2>\n<p>Ipamorelin binds the <strong>growth hormone secretagogue receptor type 1a (GHS-R1a)<\/strong>, the endogenous receptor for ghrelin. The receptor is expressed on pituitary somatotropes and in the hypothalamic arcuate nucleus, and activation triggers a pulsatile release of growth hormone from pituitary storage granules.<\/p>\n<ul>\n<li><strong>Pulsatile GH release<\/strong> \u2014 unlike continuous recombinant GH administration, ipamorelin produces a <em>pulsatile<\/em> GH profile that more closely mimics endogenous nocturnal GH bursts. This pulsatility is important mechanistically because IGF-1 signaling is more responsive to pulsed than continuous GH exposure.<\/li>\n<li><strong>Clean hormonal selectivity<\/strong> \u2014 the defining feature of ipamorelin. Older GHRPs (GHRP-2, GHRP-6, hexarelin) also raise cortisol and prolactin, producing off-target effects that complicate research interpretation. Ipamorelin does not, making it the preferred GHRP for research where those confounders matter.<\/li>\n<li><strong>GHRH complementarity<\/strong> \u2014 ipamorelin acts via the ghrelin-receptor pathway; GHRH analogs such as <a href=\"https:\/\/medsbase.com\/el\/cjc-1295-with-dac\/\">CJC-1295<\/a> act via a parallel GHRH-receptor pathway. Co-administration produces synergistic GH pulse amplification greater than either peptide alone \u2014 the basis of the classic &#8220;ipamorelin + CJC-1295&#8221; research stack.<\/li>\n<\/ul>\n<p>Because ipamorelin works through the body&#8217;s own pituitary GH supply, it is subject to normal negative-feedback regulation by somatostatin and IGF-1. This auto-regulation is a research-relevant safety feature distinguishing secretagogues from exogenous recombinant GH.<\/p>\n<h2>Published Research Applications<\/h2>\n<p>Ipamorelin is used in laboratory research contexts that investigate:<\/p>\n<ul>\n<li><strong>GH pulse research<\/strong> \u2014 pulsatile growth-hormone release kinetics and IGF-1 response in rodent models (Raun et al., Eur J Endocrinol 1998)<\/li>\n<li><strong>Skeletal muscle recovery<\/strong> \u2014 post-injury and post-exercise recovery, often stacked with <a href=\"https:\/\/medsbase.com\/el\/bpc-157\/\">BPC-157<\/a> \u03ba\u03b1\u03b9 <a href=\"https:\/\/medsbase.com\/el\/tb-500\/\">TB-500<\/a><\/li>\n<li><strong>Body composition research<\/strong> \u2014 lean-mass preservation and fat-mass research, often in caloric-deficit or disuse-atrophy models<\/li>\n<li><strong>Sleep research<\/strong> \u2014 slow-wave sleep and nocturnal GH-surge research; pre-sleep dosing is the typical research timing<\/li>\n<li><strong>Bone density research<\/strong> \u2014 osteoblast activity and bone mineral density via GH\/IGF-1 axis modulation<\/li>\n<li><strong>CJC-1295 stacking research<\/strong> \u2014 synergistic GH amplification protocols with GHRH analogs (see the <a href=\"https:\/\/medsbase.com\/el\/ipamorelin-cjc-1295-stack-guide\/\">Ipamorelin + CJC-1295 stack guide<\/a>)<\/li>\n<\/ul>\n<p>For broader context on the GH-axis peptide landscape, see <a href=\"https:\/\/medsbase.com\/el\/peptides\/\">the research peptides catalog<\/a>.<\/p>\n<h2>Available Strengths and Concentrations<\/h2>\n<p>MedsBase stocks ipamorelin in the following lyophilized vial sizes. Each variation ships in 10-vial, 20-vial, or 30-vial pack formats:<\/p>\n<table style=\"width: 100%; border-collapse: collapse; margin: 16px 0;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">Vial Strength<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">Typical Use Case<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">Pack Sizes<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>2\u00a0mg<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Short research protocols, pilot dosing<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">10, 20, or 30 vials<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>5\u00a0mg<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Standard research strength, most commonly ordered<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">10, 20, or 30 vials<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>10\u00a0mg<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Extended research, lowest per-mg cost<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">10, 20, or 30 vials<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>All three strengths are the same chemical form (lyophilized powder, 99%+ HPLC purity). A 5\u00a0mg vial at 2.5\u00a0mg\/mL dilution delivers approximately 16 administrations of 300\u00a0mcg, matching common research protocols.<\/p>\n<h2>How It Compares \u2014 Ipamorelin vs CJC-1295<\/h2>\n<p>Ipamorelin and <a href=\"https:\/\/medsbase.com\/el\/cjc-1295-with-dac\/\">CJC-1295 with DAC<\/a> are the two most-studied GH-axis peptides. They are near-universally co-administered rather than substituted, because they act on <em>parallel<\/em> receptor systems that produce synergy together:<\/p>\n<table style=\"width: 100%; border-collapse: collapse; margin: 16px 0;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">Criterion<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">\u0399\u03c0\u03b1\u03bc\u03bf\u03c1\u03b5\u03bb\u03af\u03bd\u03b7<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">CJC-1295 with DAC<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Peptide class<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">GHRP (growth-hormone-releasing peptide)<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">GHRH analog (growth-hormone-releasing hormone)<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Receptor<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">GHS-R1a (ghrelin receptor)<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">GHRH receptor on somatotropes<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Effect on GH<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Pulsatile burst release<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Sustained baseline elevation<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Half-life<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">~2 hours<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">~7 days (albumin-bound)<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u03a7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">200\u2013300\u00a0mcg, 2\u20133x daily<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">1\u20132\u00a0mg weekly<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>Stacking<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Canonical pairing with CJC-1295<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">Canonical pairing with ipamorelin<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>The full stacking rationale, dose-timing, and synergy-mechanism analysis are in our <a href=\"https:\/\/medsbase.com\/el\/ipamorelin-cjc-1295-stack-guide\/\">Ipamorelin and CJC-1295 stack research guide<\/a>.<\/p>\n<h2>Storage and Reconstitution<\/h2>\n<p><strong>Before reconstitution:<\/strong> store lyophilized vials refrigerated at 2\u20138\u00a0\u00b0C in original packaging, stable up to 36 months. Avoid freeze-thaw cycles on the powder.<\/p>\n<p><strong>Reconstitution procedure:<\/strong> inject bacteriostatic water down the side wall of the peptide vial per the chart above. Swirl gently \u2014 do <strong>\u03b4\u03b5\u03bd<\/strong> shake \u2014 and allow 5\u201310 minutes for full dissolution. A correctly reconstituted solution should be clear and colourless.<\/p>\n<p><strong>After reconstitution:<\/strong> store refrigerated at 2\u20138\u00a0\u00b0C and use within 30 days. Do not freeze reconstituted solution \u2014 freeze-thaw cycles degrade peptide integrity.<\/p>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3>What is ipamorelin used for in research?<\/h3>\n<p>Ipamorelin is used in laboratory research investigating pulsatile growth hormone release, IGF-1 axis signaling, skeletal muscle recovery, body composition, sleep research, bone density, and GH-axis stacking with GHRH analogs. It is <strong>\u03b4\u03b5\u03bd<\/strong> FDA-approved and is sold here strictly for laboratory research use only.<\/p>\n<h3>What is the typical ipamorelin research dose?<\/h3>\n<p>Published preclinical protocols typically use 200\u2013300\u00a0mcg per administration, 2\u20133 times daily, often with one dose timed pre-sleep to align with nocturnal GH-surge research. A 5\u00a0mg vial reconstituted with 2.0\u00a0mL bacteriostatic water yields 2.5\u00a0mg\/mL \u2014 12 ticks on a U-100 syringe delivers 300\u00a0mcg.<\/p>\n<h3>How is ipamorelin different from CJC-1295?<\/h3>\n<p>Ipamorelin is a GHRP (growth-hormone-releasing peptide) that binds the ghrelin receptor for pulsatile GH release. CJC-1295 is a GHRH (growth-hormone-releasing hormone) analog that binds a different receptor on the same pituitary cells for sustained GH elevation. The two are typically stacked because their mechanisms are additive\/synergistic.<\/p>\n<h3>Is ipamorelin FDA approved?<\/h3>\n<p>No. Ipamorelin is not approved by the FDA, EMA, MHRA, or any other regulator for human therapeutic use. It has been studied in early-phase human clinical trials but never advanced to approval. All ipamorelin sold by research-use-only suppliers is for laboratory investigation only.<\/p>\n<h3>Why is ipamorelin preferred over older GHRPs like GHRP-6?<\/h3>\n<p>Ipamorelin&#8217;s defining feature is clean hormonal selectivity \u2014 it releases GH without raising cortisol, prolactin, or ACTH. Older GHRPs (GHRP-2, GHRP-6, hexarelin) raise all three, producing off-target effects that complicate research interpretation and produce unwanted side effects. This selectivity has made ipamorelin the most-studied GHRP of the past two decades.<\/p>\n<h3>How should ipamorelin be stored?<\/h3>\n<p>Lyophilized vials: refrigerated at 2\u20138\u00a0\u00b0C in original packaging, stable up to 36 months. Reconstituted solution: refrigerated at 2\u20138\u00a0\u00b0C, use within 30 days. Do not freeze reconstituted solution \u2014 freeze-thaw cycles degrade the peptide.<\/p>\n<h3>How do I reconstitute ipamorelin?<\/h3>\n<p>Follow the reconstitution chart above. Add bacteriostatic water down the side wall of the vial, swirl gently, and allow 5\u201310 minutes for full dissolution. Do <strong>\u03b4\u03b5\u03bd<\/strong> shake the vial.<\/p>\n<h3>Can ipamorelin and CJC-1295 be stacked in research?<\/h3>\n<p>Yes. The ipamorelin + CJC-1295 combination is the canonical GH-axis research stack. The two peptides act on parallel receptor systems (ghrelin vs GHRH receptor) and their effects on GH release are synergistic \u2014 combined use produces larger GH pulses than either alone. See our <a href=\"https:\/\/medsbase.com\/el\/ipamorelin-cjc-1295-stack-guide\/\">stack guide<\/a>.<\/p>\n<h3>What strengths does MedsBase stock?<\/h3>\n<p>MedsBase carries ipamorelin in 2\u00a0mg, 5\u00a0mg, and 10\u00a0mg lyophilized vials. Each strength is available in 10-vial, 20-vial, or 30-vial pack sizes. All vials are supplied at 99%+ HPLC purity with a certificate of analysis on request.<\/p>\n<h3>Does ipamorelin cause side effects in research?<\/h3>\n<p>Ipamorelin has been reported with a clean safety profile at typical research doses. Its selective receptor binding avoids the cortisol and prolactin elevation seen with older GHRPs. Long-term human safety data are not available because human trials were not completed.<\/p>\n<h3>Why is pre-sleep timing used in ipamorelin research?<\/h3>\n<p>Endogenous growth-hormone release is naturally pulsatile and strongest during slow-wave sleep. Research protocols typically time one ipamorelin dose 30\u201360 minutes before sleep to amplify the natural nocturnal GH surge rather than compete with daytime somatostatin tone.<\/p>\n<h3>What is the half-life of Ipamorelin?<\/h3>\n<p>Ipamorelin has a short plasma half-life of approximately 2 hours in preclinical research, consistent with the broader GHRP peptide class. This rapid clearance underpins the pulsatile, multiple-daily dosing schedules most commonly used in ipamorelin research protocols.<\/p>\n<h3>How does Ipamorelin compare to GHRP-6 in research?<\/h3>\n<p>Ipamorelin is highly selective for the GHSR-1a receptor and does not significantly elevate cortisol or prolactin in preclinical studies \u2014 a key distinction from GHRP-6, which activates ghrelin receptors more broadly and is associated with transient cortisol and prolactin increases. This selectivity is a primary reason ipamorelin is frequently preferred in published GH-secretagogue research.<\/p>\n<h3>Can I order ipamorelin for international shipping?<\/h3>\n<p>Yes. MedsBase ships ipamorelin worldwide from our dedicated peptide shipping network. Peptide-only orders qualify for our standalone peptide shipping service. Orders ship in temperature-controlled packaging with full tracking.<\/p>\n<p class=\"medsbase-bundle-link-2026-05-01\" data-marker=\"mb-bundle-link-peptide-healing-stack\">If your recovery protocol pairs ipamorelin&#8217;s GH-pulse stimulation with direct tissue-repair peptides for tendon or ligament work, our <a href=\"\/el\/peptide-healing-stack\/\">Peptide Healing Stack (BPC-157 5 mg + TB-500 5 mg)<\/a> covers the angiogenesis + cytoskeletal-repair side of the regimen with bacteriostatic water included for reconstitution.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>\u0386\u03bb\u03bb\u03b1 \u03c0\u03b5\u03c0\u03c4\u03af\u03b4\u03b9\u03b1 \u03b3\u03b9\u03b1 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b1\u03bd\u03ac\u03ba\u03b1\u03bc\u03c8\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03cc\u03b4\u03bf\u03c3\u03b7\u03c2<\/h2>\n<ul>\n<li><a href=\"\/el\/bpc-157\/\"><strong>BPC-157<\/strong><\/a> \u2014 Body Protection Compound \u2014 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b1\u03bd\u03ac\u03ba\u03b1\u03bc\u03c8\u03b7\u03c2 \u03c4\u03ad\u03bd\u03bf\u03bd\u03c4\u03b1, \u03c3\u03c5\u03bd\u03b4\u03ad\u03c3\u03bc\u03bf\u03c5, \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5<\/li>\n<li><a href=\"\/el\/tb-500\/\"><strong>TB-500<\/strong><\/a> \u2014 \u0398\u03c1\u03b1\u03cd\u03c3\u03bc\u03b1 Thymosin Beta-4 \u2014 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b1\u03bd\u03ac\u03ba\u03b1\u03bc\u03c8\u03b7\u03c2 \u03bc\u03b1\u03bb\u03b1\u03ba\u03ce\u03bd \u03b9\u03c3\u03c4\u03ce\u03bd \u03ba\u03b1\u03b9 \u03b1\u03b3\u03b3\u03b5\u03af\u03c9\u03bd<\/li>\n<li><a href=\"\/el\/cjc-1295-with-dac\/\"><strong>CJC-1295 with DAC<\/strong><\/a> \u2014 \u0391\u03bd\u03b1\u03bb\u03bf\u03b3\u03b9\u03ba\u03cc GHRH \u03bc\u03b5 \u03c0\u03b1\u03c1\u03b1\u03c4\u03b5\u03c4\u03b1\u03bc\u03ad\u03bd\u03bf \u03c7\u03c1\u03cc\u03bd\u03bf \u03b7\u03bc\u03b9\u03b6\u03c9\u03ae\u03c2<\/li>\n<li><a href=\"\/el\/ghk-cu\/\"><strong>GHK-Cu<\/strong><\/a> \u2014 \u03a0\u03b5\u03c0\u03c4\u03af\u03b4\u03b9\u03bf \u03c7\u03b1\u03bb\u03ba\u03bf\u03cd \u2014 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03b1\u03b3\u03ad\u03bd\u03bd\u03b7\u03c3\u03b7 \u03b4\u03ad\u03c1\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bd\u03b4\u03b5\u03c4\u03b9\u03ba\u03bf\u03cd \u03b9\u03c3\u03c4\u03bf\u03cd<\/li>\n<li><a href=\"\/el\/igf-1-lr3\/\"><strong>IGF-1 LR3<\/strong><\/a> \u2014 Long-R3 IGF-1 analog \u2014 anabolic \/ regenerative research<\/li>\n<\/ul>\n<p><!-- medsbase-peptide-guide-cta --><\/p>\n<h2>\u03a0\u03b5\u03c1\u03b1\u03b9\u03c4\u03ad\u03c1\u03c9 \u03b1\u03bd\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7<\/h2>\n<div style=\"background: #f4f8fb; border-left: 4px solid #2c7cb0; padding: 18px 22px; margin: 18px 0; border-radius: 4px;\">\n<p style=\"margin: 0 0 8px 0;\"><strong>\ud83d\udcd6 \u039c\u03ac\u03b8\u03b5\u03c4\u03b5 \u03c4\u03b7\u03bd \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03c0\u03af\u03c3\u03c9 \u03b1\u03c0\u03cc \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03c0\u03b5\u03c0\u03c4\u03af\u03b4\u03b9\u03bf<\/strong><\/p>\n<p style=\"margin: 0;\">\u0394\u03b9\u03b1\u03b2\u03ac\u03c3\u03c4\u03b5 \u03c4\u03bf\u03bd \u03c0\u03bb\u03ae\u03c1\u03b7 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03c4\u03b9\u03ba\u03ac \u03c4\u03b5\u03ba\u03bc\u03b7\u03c1\u03b9\u03c9\u03bc\u03ad\u03bd\u03bf \u03bf\u03b4\u03b7\u03b3\u03cc \u03bc\u03b1\u03c2: <a href=\"https:\/\/medsbase.com\/el\/ipamorelin-cjc-1295-stack-guide\/\"><strong>Ipamorelin &amp; CJC-1295 \u2014 mechanism, stacking &amp; protocols<\/strong><\/a>. Covers mechanism of action, ghrelin vs GHRH receptor pharmacology, published stacking protocols, reconstitution, dose-timing, and safety notes.<\/p>\n<\/div>\n<p><!-- pep-seo-v1 --><\/p>","protected":false},"excerpt":{"rendered":"<p>\u2705 Supports lean muscle<br \/>\n\u2705 Enhances recovery pathways<br \/>\n\u2705 Promotes metabolic balance<br \/>\n\u2705 Improves sleep cycles<br \/>\n\u2705 Boosts tissue repair<\/p>\n<p><strong>\u0399\u03c0\u03b1\u03bc\u03bf\u03c1\u03b5\u03bb\u03af\u03bd\u03b7<\/strong> \u03c0\u03b5\u03c1\u03b9\u03ad\u03c7\u03b5\u03b9 \u03c3\u03c5\u03bd\u03b8\u03b5\u03c4\u03b9\u03ba\u03ae \u03c0\u03b5\u03c0\u03c4\u03b9\u03b4\u03b9\u03ba\u03ae \u03ad\u03bd\u03c9\u03c3\u03b7.<\/p>","protected":false},"featured_media":70961,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[5426],"product_tag":[5457],"class_list":{"0":"post-68897","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptides","7":"product_tag-ipamorelin","9":"first","10":"instock","11":"shipping-taxable","12":"purchasable","13":"product-type-variable","14":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/68897","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=68897"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/70961"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=68897"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=68897"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=68897"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=68897"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}