{"id":71742,"date":"2026-05-23T13:13:05","date_gmt":"2026-05-23T13:13:05","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&#038;p=71742"},"modified":"2026-05-23T13:13:06","modified_gmt":"2026-05-23T13:13:06","slug":"trivon","status":"publish","type":"product","link":"https:\/\/medsbase.com\/el\/trivon\/","title":{"rendered":"Trivon Tablet &#8211; Tranylcypromine"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background: #fff8e1; border-left: 4px solid #f5a623; padding: 18px 22px; margin: 0 0 24px 0; border-radius: 4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin: 0 0 8px 0; font-size: 16px; font-weight: bold;\">\u26a1 Quick Answer \u2014 What is Trivon Tablet?<\/h3>\n<p style=\"margin: 0;\"><strong>Trivon<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>tranylcypromine 10\u00a0mg<\/strong> tablet \u2014 a <strong>monoamine oxidase inhibitor (MAOI)<\/strong> antidepressant used mainly for <strong>treatment-resistant major depression<\/strong> \u03ba\u03b1\u03b9 <strong>atypical depression<\/strong> that has not responded to SSRIs, SNRIs, or other antidepressants. It works by blocking the monoamine oxidase enzyme, raising brain levels of <strong>serotonin, noradrenaline, and dopamine<\/strong>. Trivon is the generic equivalent of <strong>Parnate<sup>\u00ae<\/sup><\/strong>. Because of its food and drug interactions, it requires a <strong>tyramine-restricted diet<\/strong> and specialist supervision.<\/p>\n<\/div>\n<p><!-- medsbase-specialist-strip --><\/p>\n<div style=\"background: #fff3f3; border-left: 4px solid #d9534f; padding: 16px 20px; margin: 0 0 24px 0; border-radius: 4px; font-size: 14px;\"><strong>\u2695 Specialist-supervised medicine \u2014 clinician oversight required.<\/strong> Tranylcypromine is a non-selective irreversible MAO inhibitor with a <strong>strict tyramine-restricted diet<\/strong>, a risk of <strong>hypertensive (tyramine) crisis<\/strong>, and mandatory <strong>washout periods<\/strong> when switching to or from other antidepressants. It should be started and supervised by a psychiatrist or doctor experienced with MAOIs. Do <strong>\u03b4\u03b5\u03bd<\/strong> self-adjust the dose, combine it with other serotonergic or stimulant medicines, or start\/stop without your prescriber&#8217;s direction. Always tell your treating doctor every medicine and supplement you take before ordering from MedsBase.<\/div>\n<p><strong>Trivon<\/strong> \u03b5\u03af\u03bd\u03b1\u03b9 <strong>tranylcypromine<\/strong> \u03b4\u03b9\u03c3\u03ba\u03af\u03bf \u03c0\u03bf\u03c5 \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 <strong>depression<\/strong>, particularly forms that have not improved with newer antidepressants. Each tablet contains <strong>10\u00a0mg of tranylcypromine sulfate<\/strong>. It belongs to the oldest class of antidepressants \u2014 the <strong>monoamine oxidase inhibitors (MAOIs)<\/strong> \u2014 and is the generic equivalent of <strong>Parnate<sup>\u00ae<\/sup><\/strong>.<\/p>\n<p>Tranylcypromine is reserved for <strong>treatment-resistant depression (TRD)<\/strong> \u03ba\u03b1\u03b9 <strong>atypical depression<\/strong> (depression with mood reactivity, increased sleep and appetite, leaden paralysis, and rejection sensitivity), where MAOIs are often more effective than SSRIs. Its structure is related to amphetamine, which gives it a mild activating, energising quality some patients find helpful for low energy and anhedonia.<\/p>\n<h2 class=\"wp-block-heading\">What Is Trivon (Tranylcypromine)?<\/h2>\n<p>Trivon is an <strong>MAOI antidepressant<\/strong> that irreversibly inhibits the enzyme <strong>monoamine oxidase (both MAO-A and MAO-B)<\/strong>. By blocking the enzyme that breaks down monoamine neurotransmitters, it increases the available pool of <strong>serotonin (5-HT)<\/strong>, <strong>noradrenaline (norepinephrine)<\/strong>, \u03ba\u03b1\u03b9 <strong>dopamine<\/strong> in the brain.<\/p>\n<p>Trivon is most commonly used for:<\/p>\n<ul>\n<li><strong>Treatment-resistant major depression<\/strong> \u2014 depression that has failed two or more adequate trials of other antidepressants<\/li>\n<li><strong>Atypical depression<\/strong> \u2014 mood reactivity, hypersomnia, increased appetite, and rejection sensitivity, where MAOIs have historically shown superior response<\/li>\n<li><strong>Depression with marked anergia and anhedonia<\/strong> \u2014 its mild stimulant character can help with low drive and motivation<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">How Does Trivon Work?<\/h2>\n<p>Tranylcypromine acts as a <strong>non-selective, irreversible monoamine oxidase inhibitor<\/strong>:<\/p>\n<ul>\n<li>It binds to and permanently inactivates both <strong>MAO-A<\/strong> \u03ba\u03b1\u03b9 <strong>MAO-B<\/strong>, the enzymes that metabolise serotonin, noradrenaline, dopamine, and dietary amines such as tyramine<\/li>\n<li>Because the inhibition is <strong>irreversible<\/strong>, the effect lasts until the body synthesises new enzyme \u2014 which takes roughly <strong>1\u20132 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong> after the last dose<\/li>\n<li>The resulting rise in synaptic monoamines is thought to underlie its antidepressant effect, especially in atypical and treatment-resistant presentations<\/li>\n<li>Its cyclopropylamine structure is related to amphetamine, contributing a mild stimulant-like activating effect<\/li>\n<\/ul>\n<p>Antidepressant benefit usually begins within <strong>1\u20133 weeks<\/strong>, with full effect over <strong>4\u20136 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong>. Because MAO-A inhibition also reduces breakdown of dietary <strong>tyramine<\/strong>, \u03ad\u03bd\u03b1 <strong>tyramine-restricted diet is mandatory<\/strong> throughout treatment and for two weeks after stopping.<\/p>\n<h2 class=\"wp-block-heading\">\u03a7\u03c1\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03bd\u03b4\u03b5\u03af\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Treatment-resistant major depressive disorder<\/strong> \u2014 a recognised option after multiple failed antidepressant trials<\/li>\n<li><strong>Atypical depression<\/strong> \u2014 a historically strong indication for MAOIs<\/li>\n<li><strong>Depression with prominent low energy, hypersomnia, and anhedonia<\/strong><\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Trivon Dosage and Administration<\/h2>\n<table>\n<thead>\n<tr>\n<th>Situation<\/th>\n<th>Starter Dose<\/th>\n<th>Target \/ Max Dose<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>Major \/ treatment-resistant depression<\/strong><\/td>\n<td>10 mg twice daily (morning &amp; midday)<\/td>\n<td>Increase by 10 mg every 1\u20133 weeks; usual 20\u201340 mg\/day; max 60 mg\/day<\/td>\n<\/tr>\n<tr>\n<td><strong>Maintenance after response<\/strong><\/td>\n<td>Lowest effective dose<\/td>\n<td>Often 10\u201320 mg\/day<\/td>\n<\/tr>\n<tr>\n<td><strong>Elderly patients<\/strong><\/td>\n<td>10 mg \u03bc\u03b9\u03b1 \u03c6\u03bf\u03c1\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03ad\u03c1\u03b1<\/td>\n<td>Titrate slowly; lower ceiling, watch postural blood pressure<\/td>\n<\/tr>\n<tr>\n<td><strong>Last dose timing<\/strong><\/td>\n<td colspan=\"2\">Avoid late-afternoon or evening dosing \u2014 the activating effect commonly causes insomnia<\/td>\n<\/tr>\n<tr>\n<td><strong>Stopping treatment<\/strong><\/td>\n<td colspan=\"2\">Taper gradually under supervision; maintain the tyramine diet for 14 days after the last dose<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"wp-block-heading\">How to Take Trivon Properly<\/h3>\n<ul>\n<li>Take with or after food to reduce stomach upset<\/li>\n<li>Take the <strong>last dose by early afternoon<\/strong> to avoid insomnia<\/li>\n<li>Follow the <strong>tyramine-restricted diet<\/strong> strictly \u2014 see the dietary warning below<\/li>\n<li>\u039a\u03ac\u03bd\u03c4\u03b5 <strong>\u03b4\u03b5\u03bd<\/strong> take any other antidepressant, opioid, cough\/cold remedy, or stimulant without checking with your prescriber<\/li>\n<li>\u0395\u03c0\u03b9\u03c4\u03c1\u03ad\u03c8\u03c4\u03b5 <strong>1\u20133 weeks<\/strong> for early response and up to <strong>6 weeks<\/strong> for full effect<\/li>\n<li>Do not stop abruptly; taper under medical supervision<\/li>\n<li>Carry a card or note stating that you take an MAOI, in case of emergency treatment<\/li>\n<\/ul>\n<div style=\"background: #fff3f3; border-left: 4px solid #d9534f; padding: 16px 20px; margin: 24px 0; border-radius: 4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin: 0 0 8px 0;\">\u26a0\ufe0f Tyramine diet \u2014 avoid a hypertensive crisis<\/h3>\n<p style=\"margin: 0 0 8px;\">Because tranylcypromine blocks the enzyme that breaks down dietary <strong>tyramine<\/strong>, eating high-tyramine foods can cause a dangerous surge in blood pressure (\u201c<strong>tyramine<\/strong> \u03ae <strong>cheese reaction<\/strong>\u201d) \u2014 sudden severe headache, palpitations, neck stiffness, nausea, or chest pain. Seek emergency care immediately if these occur.<\/p>\n<p style=\"margin: 0;\"><strong>Avoid:<\/strong> aged or mature cheeses \u00b7 cured, smoked, or fermented meats (salami, pepperoni) \u00b7 fermented soy (soy sauce, miso, tofu left to age) \u00b7 sauerkraut and kimchi \u00b7 draught\/tap beer and unpasteurised beer \u00b7 Marmite\/Vegemite and concentrated yeast extracts \u00b7 broad (fava) beans \u00b7 overripe or spoiled fruit \u00b7 any aged, pickled, or fermented food. Fresh foods eaten promptly are generally safe.<\/p>\n<\/div>\n<h2 class=\"wp-block-heading\">Side Effects of Trivon<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u0392\u03b1\u03c1\u03cd\u03c4\u03b7\u03c4\u03b1<\/th>\n<th>\u03a0\u03b1\u03c1\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>\u03a3\u03c5\u03c7\u03bd\u03ac<\/strong><\/td>\n<td>Insomnia, agitation or restlessness, dizziness, postural (orthostatic) low blood pressure, dry mouth, headache, constipation<\/td>\n<\/tr>\n<tr>\n<td><strong>Less common<\/strong><\/td>\n<td>Weight change, blurred vision, sweating, tremor, sexual dysfunction, oedema, fatigue once the activating effect settles<\/td>\n<\/tr>\n<tr>\n<td><strong>\u03a3\u03c0\u03ac\u03bd\u03b9\u03b1 \u03b1\u03bb\u03bb\u03ac \u03c3\u03bf\u03b2\u03b1\u03c1\u03ae<\/strong><\/td>\n<td>Hypertensive (tyramine) crisis, serotonin syndrome (when combined with other serotonergic drugs), hepatotoxicity, mania in susceptible patients, suicidal ideation (especially in young adults)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Orthostatic hypotension<\/strong> (dizziness on standing) is one of the most common limiting effects \u2014 stand up slowly and stay hydrated. <strong>\u0391\u03cb\u03c0\u03bd\u03af\u03b1<\/strong> is best managed by taking the last dose early in the day.<\/p>\n<h2 class=\"wp-block-heading\">\u03a0\u03c1\u03bf\u03b5\u03b9\u03b4\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03b5\u03b9\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c6\u03c5\u03bb\u03ac\u03be\u03b5\u03b9\u03c2<\/h2>\n<ul>\n<li><strong>Tyramine crisis.<\/strong> Strict dietary compliance is essential (see the diet box above), throughout treatment and for 14 days afterwards<\/li>\n<li><strong>Serotonin syndrome.<\/strong> Do not combine with SSRIs, SNRIs, tricyclics, triptans, tramadol, pethidine, dextromethorphan, St John&#8217;s Wort, or linezolid. Observe washout periods in both directions<\/li>\n<li><strong>Blood pressure.<\/strong> Both high (tyramine reaction) and low (orthostatic) blood pressure are possible \u2014 monitor regularly<\/li>\n<li><strong>Suicidal thoughts.<\/strong> Like all antidepressants, carries a warning for suicidal ideation in those under 25; monitor closely early in treatment and after dose changes<\/li>\n<li><strong>Surgery \/ anaesthesia.<\/strong> Tell any surgeon, dentist, or anaesthetist that you take an MAOI well in advance<\/li>\n<li><strong>Pregnancy \/ breastfeeding.<\/strong> Use only if the benefit clearly outweighs the risk and under specialist advice<\/li>\n<li><strong>\u0391\u03bb\u03ba\u03bf\u03cc\u03bb.<\/strong> Avoid \u2014 some alcoholic drinks are also high in tyramine<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Contraindications \u2014 Who Should NOT Take Trivon<\/h2>\n<ul>\n<li><strong>\u03a6\u03b1\u03b9\u03bf\u03c7\u03c1\u03c9\u03bc\u03bf\u03ba\u03cd\u03c4\u03c4\u03c9\u03bc\u03b1<\/strong> (catecholamine-secreting tumour)<\/li>\n<li><strong>Cerebrovascular disease, established cardiovascular disease, or uncontrolled hypertension<\/strong><\/li>\n<li><strong>Concurrent use of other antidepressants, opioids (especially pethidine), or sympathomimetics<\/strong><\/li>\n<li><strong>\u03a3\u03bf\u03b2\u03b1\u03c1\u03ae \u03b7\u03c0\u03b1\u03c4\u03b9\u03ba\u03ae \u03b4\u03c5\u03c3\u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1<\/strong><\/li>\n<li>Within the required <strong>washout window<\/strong> of another serotonergic drug (e.g. 5 weeks after fluoxetine)<\/li>\n<li>Known hypersensitivity to tranylcypromine<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03b9\u03b4\u03c1\u03ac\u03c3\u03b5\u03b9\u03c2 \u03a6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd<\/h2>\n<table>\n<thead>\n<tr>\n<th>\u03a6\u03ac\u03c1\u03bc\u03b1\u03ba\u03bf \/ \u03a4\u03ac\u03be\u03b7<\/th>\n<th>\u0391\u03bb\u03bb\u03b7\u03bb\u03b5\u03c0\u03af\u03b4\u03c1\u03b1\u03c3\u03b7<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong>SSRIs, SNRIs, tricyclics (sertraline, venlafaxine, amitriptyline)<\/strong><\/td>\n<td><strong>\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03c4\u03b1\u03b9<\/strong> \u2014 serotonin syndrome risk. 14-day washout after stopping the MAOI; <strong>5 weeks<\/strong> after fluoxetine before starting it<\/td>\n<\/tr>\n<tr>\n<td><strong>Other MAOIs \/ linezolid \/ methylene blue<\/strong><\/td>\n<td><strong>\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03c4\u03b1\u03b9<\/strong> \u2014 additive MAO inhibition<\/td>\n<\/tr>\n<tr>\n<td><strong>Triptans, tramadol, pethidine, dextromethorphan<\/strong><\/td>\n<td>Serotonin syndrome risk \u2014 avoid<\/td>\n<\/tr>\n<tr>\n<td><strong>Sympathomimetics &amp; decongestants (pseudoephedrine, phenylephrine, ephedrine, stimulants)<\/strong><\/td>\n<td>Hypertensive crisis \u2014 avoid all OTC cold\/flu and decongestant products<\/td>\n<\/tr>\n<tr>\n<td><strong>Bupropion<\/strong><\/td>\n<td><strong>\u0391\u03bd\u03c4\u03b5\u03bd\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03c4\u03b1\u03b9<\/strong> \u2014 14-day washout either direction<\/td>\n<\/tr>\n<tr>\n<td><strong>\u0391\u03bd\u03c4\u03b9\u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03ac<\/strong><\/td>\n<td>Additive blood-pressure lowering \u2014 monitor for hypotension<\/td>\n<\/tr>\n<tr>\n<td><strong>Alcohol &amp; tyramine-rich foods<\/strong><\/td>\n<td>Hypertensive reaction \u2014 see diet box<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Always share a full list of prescription medicines, over-the-counter products, herbal supplements, and recreational drugs with your prescriber before starting Trivon.<\/p>\n<h2 class=\"wp-block-heading\">\u03a4\u03b9 \u03bd\u03b1 \u039a\u03ac\u03bd\u03b5\u03c4\u03b5 \u03c3\u03b5 \u03a0\u03b5\u03c1\u03af\u03c0\u03c4\u03c9\u03c3\u03b7 \u03a5\u03c0\u03b5\u03c1\u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2<\/h2>\n<p>MAOI overdose can be serious and its effects may be <strong>delayed up to 12 hours<\/strong>. Symptoms include agitation, severe headache, hypertension or hypotension, rapid heartbeat, hyperthermia, muscle rigidity, and seizures. There is no specific antidote \u2014 treatment is supportive in hospital with cardiovascular and temperature monitoring. Seek emergency care immediately if an overdose is suspected, even if the person seems well at first.<\/p>\n<h2 class=\"wp-block-heading\">\u039f\u03b4\u03b7\u03b3\u03af\u03b5\u03c2 \u0391\u03c0\u03bf\u03b8\u03ae\u03ba\u03b5\u03c5\u03c3\u03b7\u03c2<\/h2>\n<ul>\n<li>Store below 25\u00a0\u00b0C in a dry place, away from direct sunlight<\/li>\n<li>\u0394\u03b9\u03b1\u03c4\u03b7\u03c1\u03ae\u03c3\u03c4\u03b5 \u03c3\u03c4\u03b7\u03bd \u03b1\u03c1\u03c7\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u03c6\u03c5\u03c3\u03b1\u03bb\u03af\u03b4\u03c9\u03bd<\/li>\n<li>\u039c\u03b1\u03ba\u03c1\u03b9\u03ac \u03b1\u03c0\u03cc \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac<\/li>\n<li>\u039c\u03b7\u03bd \u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03b9\u03b5\u03af\u03c4\u03b5 \u03bc\u03b5\u03c4\u03ac \u03c4\u03b7\u03bd \u03b7\u03bc\u03b5\u03c1\u03bf\u03bc\u03b7\u03bd\u03af\u03b1 \u03bb\u03ae\u03be\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03b1\u03bd\u03b1\u03b3\u03c1\u03ac\u03c6\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1<\/li>\n<li>\u0391\u03c0\u03bf\u03c1\u03c1\u03af\u03c8\u03c4\u03b5 \u03c4\u03b1 \u03b1\u03c7\u03c1\u03b7\u03c3\u03b9\u03bc\u03bf\u03c0\u03bf\u03af\u03b7\u03c4\u03b1 \u03b4\u03b9\u03c3\u03ba\u03af\u03b1 \u03bc\u03ad\u03c3\u03c9 \u03c3\u03c5\u03c3\u03c4\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u03b5\u03c0\u03b9\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae\u03c2 \u03c3\u03b5 \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03af\u03bf, \u03cc\u03c0\u03bf\u03c5 \u03b1\u03c5\u03c4\u03cc \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u03a3\u03c7\u03b5\u03c4\u03b9\u03ba\u03ad\u03c2 \u0395\u03bd\u03b1\u03bb\u03bb\u03b1\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u039b\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c3\u03c4\u03bf MedsBase<\/h2>\n<p>Looking for other antidepressant options?<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/el\/selgin\/\" rel=\"noopener\">Selgin<\/a> \u2014 selegiline, a selective MAO-B inhibitor with a lower dietary-tyramine burden at low doses<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/sertima\/\" rel=\"noopener\">Sertima<\/a> \u2014 sertraline, a first-line SSRI often tried before an MAOI (note the required washout between them)<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/bupron-xl\/\" rel=\"noopener\">Bupron XL<\/a> \u2014 bupropion, an NDRI used for low energy and motivation (contraindicated together with MAOIs)<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/mirtaz\/\" rel=\"noopener\">Mirtaz<\/a> \u2014 mirtazapine, an atypical antidepressant useful for poor sleep and appetite<\/li>\n<li><a href=\"https:\/\/medsbase.com\/el\/mental-health-and-psychiatric-medications\/\" rel=\"noopener\">Browse all Mental Health medications \u2192<\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">\u03a3\u03c5\u03c7\u03bd\u03ad\u03c2 \u0395\u03c1\u03c9\u03c4\u03ae\u03c3\u03b5\u03b9\u03c2<\/h2>\n<h3 class=\"wp-block-heading\">What is Trivon used for?<\/h3>\n<p>Trivon (tranylcypromine 10\u00a0mg) is an MAOI antidepressant used mainly for <strong>\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1-\u03b1\u03bd\u03b8\u03b5\u03ba\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03c4\u03ac\u03b8\u03bb\u03b9\u03c8\u03b7<\/strong> \u03ba\u03b1\u03b9 <strong>atypical depression<\/strong> \u2014 cases that have not responded well to SSRIs, SNRIs, or other antidepressants. MAOIs are often reserved for these situations because of their dietary and drug interactions.<\/p>\n<h3 class=\"wp-block-heading\">How long does Trivon take to work?<\/h3>\n<p>An early lift in energy and mood is often noticed within <strong>1\u20133 weeks<\/strong>, with the full antidepressant effect developing over <strong>4\u20136 \u03b5\u03b2\u03b4\u03bf\u03bc\u03ac\u03b4\u03b5\u03c2<\/strong>. If there is no benefit after an adequate dose and duration, your prescriber may adjust the dose or reconsider treatment.<\/p>\n<h3 class=\"wp-block-heading\">Why do I have to avoid certain foods on Trivon?<\/h3>\n<p>Tranylcypromine blocks the enzyme that breaks down <strong>tyramine<\/strong> in food. If you eat high-tyramine foods (aged cheese, cured meats, fermented products, tap beer, yeast extracts), tyramine builds up and can cause a sudden, dangerous rise in blood pressure. A tyramine-restricted diet is essential during treatment and for 14 days after stopping.<\/p>\n<h3 class=\"wp-block-heading\">What is a tyramine or hypertensive crisis?<\/h3>\n<p>It is a sharp spike in blood pressure triggered by tyramine-rich food or certain medicines while taking an MAOI. Warning signs are a sudden severe (often throbbing) headache, neck stiffness, palpitations, sweating, nausea, or chest pain. It is a medical emergency \u2014 <strong>seek urgent care immediately<\/strong>.<\/p>\n<h3 class=\"wp-block-heading\">Can I take Trivon with other antidepressants?<\/h3>\n<p><strong>\u038c\u03c7\u03b9.<\/strong> Combining an MAOI with SSRIs, SNRIs, tricyclics, or other serotonergic drugs can cause serotonin syndrome. A washout period is required \u2014 usually <strong>14 days<\/strong> after stopping the MAOI, and <strong>5 weeks<\/strong> after stopping fluoxetine before starting it. Your prescriber will plan any switch.<\/p>\n<h3 class=\"wp-block-heading\">Can I take cold or flu medicine while on Trivon?<\/h3>\n<p>Avoid over-the-counter decongestants and many cough\/cold remedies \u2014 products containing <strong>pseudoephedrine, phenylephrine, ephedrine, or dextromethorphan<\/strong> can cause a hypertensive crisis or serotonin syndrome with an MAOI. Always check with a pharmacist or your prescriber first.<\/p>\n<h3 class=\"wp-block-heading\">Is Trivon the same as Parnate?<\/h3>\n<p>Yes in active ingredient \u2014 Trivon contains tranylcypromine sulfate, the same molecule as the brand <strong>Parnate<sup>\u00ae<\/sup><\/strong>. It is a generic equivalent at a lower price.<\/p>\n<h3 class=\"wp-block-heading\">When should I take my dose?<\/h3>\n<p>Tranylcypromine is activating, so it is usually taken in the <strong>morning and around midday<\/strong>. Taking it in the late afternoon or evening commonly causes insomnia. Follow the schedule your prescriber gives you.<\/p>\n<h3 class=\"wp-block-heading\">Does Trivon cause weight gain or sexual side effects?<\/h3>\n<p>Weight changes and sexual side effects can occur but are generally <strong>less pronounced than with many other antidepressants<\/strong>. The most common limiting effects are insomnia and dizziness from low blood pressure on standing.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop Trivon suddenly?<\/h3>\n<p>No \u2014 <strong>taper gradually<\/strong> under medical supervision to avoid discontinuation effects. Importantly, keep following the tyramine-restricted diet for <strong>14 days<\/strong> after your last dose, because the enzyme stays blocked until your body makes new enzyme.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol while taking Trivon?<\/h3>\n<p>It is best avoided. Beyond the usual effects on mood and sedation, some alcoholic drinks \u2014 especially tap\/draught beer, certain wines, and unpasteurised products \u2014 are high in tyramine and can trigger a hypertensive reaction.<\/p>\n<p><!-- medsbase-faq-h3-converted --><\/p>\n<div class=\"medsbase-trust-strip\" style=\"background: #f4f8fb; border: 1px solid #d8e3eb; padding: 12px 16px; margin: 16px 0; border-radius: 4px; font-size: 14px;\"><strong>\u0391\u03c5\u03c4\u03cc \u03c0\u03bf\u03c5 \u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03c4\u03b5 \u03bc\u03b5 \u03c4\u03b7\u03bd MedsBase:<\/strong> \u03a0\u03b9\u03c3\u03c4\u03bf\u03c0\u03bf\u03b9\u03b7\u03bc\u03ad\u03bd\u03bf\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03c4\u03ae\u03c2 WHO-GMP \u00b7 \u0394\u03b9\u03b1\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03c3\u03c5\u03c3\u03ba\u03b5\u03c5\u03b1\u03c3\u03af\u03b1 \u00b7 \u03a0\u03b1\u03b3\u03ba\u03cc\u03c3\u03bc\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae \u00b7 1,400+ \u03b5\u03c0\u03b1\u03bb\u03b7\u03b8\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 <a href=\"https:\/\/medsbase.com\/el\/reviews\/\">\u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b5\u03bb\u03b1\u03c4\u03ce\u03bd<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size: 14px; color: #444; margin: 8px 0 18px;\">\ud83d\udce6 \u039a\u03ac\u03b8\u03b5 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03bb\u03af\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c0\u03c4\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\"><strong>\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/strong><\/a> \u2014 \u03b5\u03ac\u03bd \u03c4\u03bf \u03b4\u03ad\u03bc\u03b1 \u03c3\u03b1\u03c2 \u03b4\u03b5\u03bd \u03c6\u03c4\u03ac\u03c3\u03b5\u03b9 \u03b5\u03bd\u03c4\u03cc\u03c2 20 \u03b5\u03c1\u03b3\u03ac\u03c3\u03b9\u03bc\u03c9\u03bd \u03b7\u03bc\u03b5\u03c1\u03ce\u03bd, \u03c4\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03ad\u03bb\u03bb\u03bf\u03c5\u03bc\u03b5.<\/p>\n<h3>\u0393\u03b9\u03b1\u03c4\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03b3\u03b5\u03af\u03bb\u03b5\u03c4\u03b5 \u03b1\u03c0\u03cc \u03c4\u03b7 MedsBase<\/h3>\n<p>Trivon (tranylcypromine 10\u00a0mg) at MedsBase is supplied directly from a WHO-GMP certified manufacturer in plain, discreet packaging. Every order is covered by our <a href=\"https:\/\/medsbase.com\/el\/medsbase-re-shipment-assurance-policy\/\">\u03a0\u03bf\u03bb\u03b9\u03c4\u03b9\u03ba\u03ae \u0395\u03b3\u03b3\u03cd\u03b7\u03c3\u03b7\u03c2 \u0395\u03c0\u03b1\u03bd\u03b1\u03c0\u03bf\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2<\/a> \u2014 20-business-day arrival window or we reship at no charge \u2014 and qualifies for our customer loyalty programme. Worldwide shipping is available to most destinations.<\/p>","protected":false},"excerpt":{"rendered":"<p>Trivon (Tranylcypromine 10 mg) \u2014 MAOI antidepressant for treatment-resistant and atypical depression. Generic Parnate. Requires a tyramine-restricted diet.<\/p>","protected":false},"featured_media":71748,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3906],"product_tag":[6626,6625,5681,6621,6622,6623,6620,6624,6619],"class_list":{"0":"post-71742","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-mental-health-and-psychiatric-medications","9":"product_tag-antidepressant","10":"product_tag-atypical-depression","11":"product_tag-major-depression","12":"product_tag-maoi","13":"product_tag-monoamine-oxidase-inhibitor","14":"product_tag-parnate-generic","15":"product_tag-tranylcypromine","16":"product_tag-treatment-resistant-depression","17":"product_tag-trivon","19":"first","20":"instock","21":"shipping-taxable","22":"purchasable","23":"product-type-variable","24":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product\/71742","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/comments?post=71742"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media\/71748"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/media?parent=71742"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_brand?post=71742"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_cat?post=71742"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/el\/wp-json\/wp\/v2\/product_tag?post=71742"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}