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Brimolol Eye Drop combines brimonidine 0.2% (alpha-2 agonist) with timolol 0.5% (beta-blocker) in one bottle for advanced glaucoma. Twice daily. Avoid in asthma, severe COPD, bradycardia, AV block, and children < 2 years.<\/p>\n<\/div>\n
\ud83d\udce6 Every order is covered by our Reshipment Assurance Policy<\/strong><\/a> \u2014 if your parcel does not arrive within 20 business days, we reship it.<\/p>\n Brimolol Eye Drop is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our Reshipment Assurance Policy<\/a> \u2014 if it has not arrived after 20 business days we reship at no extra cost. Backed by 1,400+ verified customer reviews.<\/p>\n Brimolol Eye Drop is a fixed-dose combination eye drop manufactured by Sun Pharma, containing brimonidine tartrate 0.2% and timolol maleate 0.5% in a 5 mL bottle. The two ingredients reduce aqueous humour production through complementary mechanisms \u2014 alpha-2 agonism and beta-adrenergic blockade \u2014 for additive ~25\u201328% IOP reduction in twice-daily dosing.<\/p>\n Brimonidine<\/strong> activates alpha-2 receptors at the ciliary epithelium, decreasing cAMP and aqueous secretion, while also increasing uveoscleral outflow. Timolol<\/strong> blocks beta-1\/beta-2 receptors at the same epithelium, further reducing aqueous production. The combination is more potent than either monotherapy.<\/p>\n One drop in affected eye(s) twice daily, ideally 12 hours apart. Wait 5 minutes if using other eye drops. Practise punctal occlusion for 1\u20132 minutes after each drop. Remove contact lenses; reinsert after 15 minutes.<\/p>\n Local:<\/strong> conjunctival hyperaemia, allergic conjunctivitis (late-onset, brimonidine signature), stinging, blurred vision, ocular pruritus.<\/p>\n Systemic:<\/strong> dry mouth, fatigue, somnolence, hypotension, bradycardia, bronchospasm in reactive airways.<\/p>\n Store at 15\u201325\u00b0C. Discard 28 days after first opening.<\/p>\n Twice daily, ideally 12 hours apart.<\/p>\n Brimonidine and timolol both reduce aqueous production but through different mechanisms. The combination is moderately additive (more than either alone) and replaces two separate bottles.<\/p>\n No \u2014 the timolol component is contraindicated. Switch to a non-beta-blocker option.<\/p>\n Press the inner corner of your eye for 1\u20132 minutes after instillation. This blocks tear drainage and reduces systemic absorption of both ingredients by ~70%.<\/p>\n Brimonidine readily crosses the blood-brain barrier and can cause life-threatening apnoea, bradycardia, and hypotension in children < 2 years. Use is contraindicated in this age group.<\/p>\n Yes \u2014 brimonidine has a characteristic late-onset allergic conjunctivitis (6\u201318 months in). Eye redness and itching after months of smooth use is a typical pattern.<\/p>\n Brimonidine can cause systemic somnolence, dry mouth, and mild hypotension. Punctal occlusion reduces this.<\/p>\n Yes \u2014 additive with prostaglandins and CAIs. Wait 5 minutes between bottles.<\/p>\n Avoid \u2014 additive sedation and hypotension are possible. Disclose to your prescriber.<\/p>\n Take it as soon as you remember unless the next dose is close.<\/p>\n <\/p>\n Customers viewing this product also consider these alternatives in our Eye Care<\/a> range:<\/p>\n The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight \u2014 sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.<\/p>\n","protected":false},"excerpt":{"rendered":" Brimolol (brimonidine + timolol 0.5%) \u2014 fixed-combination alpha-2 agonist + beta-blocker. Twice-daily IOP control for open-angle glaucoma. Paediatric apnoea contraindication.<\/p>\n","protected":false},"featured_media":55880,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3343,3342],"product_tag":[4003,3350],"class_list":{"0":"post-55879","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-eye-care","8":"product_cat-general-health","9":"product_tag-brimolol","10":"product_tag-brimonidine-tartrate","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product\/55879","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/comments?post=55879"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media\/55880"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media?parent=55879"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_brand?post=55879"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_cat?post=55879"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_tag?post=55879"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Why order from MedsBase<\/h3>\n
What is Brimolol Eye Drop?<\/h2>\n
How It Works<\/h2>\n
Dosing<\/h2>\n
Side Effects<\/h2>\n
Warnings & Contraindications<\/h2>\n
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Storage<\/h2>\n
Frequently Asked Questions<\/h2>\n
When should I take Brimolol Eye Drop?<\/h3>\n
Why combine these two drugs?<\/h3>\n
Can I use Brimolol Eye Drop if I have asthma?<\/h3>\n
What is punctal occlusion?<\/h3>\n
Why is brimonidine unsafe in young children?<\/h3>\n
Can I expect a late allergic reaction?<\/h3>\n
Will I feel tired?<\/h3>\n
Can I combine Brimolol Eye Drop with other glaucoma drops?<\/h3>\n
What if I take an MAO inhibitor?<\/h3>\n
What if I miss a dose?<\/h3>\n
Other Eye-Care Medications<\/h3>\n
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Medical Disclaimer<\/h3>\n