{"id":57192,"date":"2024-02-27T17:28:31","date_gmt":"2024-02-27T17:28:31","guid":{"rendered":"https:\/\/medsname.com\/gate-p-eye-drops\/"},"modified":"2026-04-30T10:24:30","modified_gmt":"2026-04-30T10:24:30","slug":"gate-p-eye-drops","status":"publish","type":"product","link":"https:\/\/medsbase.com\/gate-p-eye-drops\/","title":{"rendered":"Gate P Eye Drops"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"background:#fffbe6;border-left:4px solid #f5a623;padding:14px 18px;margin:14px 0 22px;border-radius:6px;font-size:15px;line-height:1.55;\">\n<h3 style=\"margin:0 0 6px;font-size:17px;color:#8a6d3b;\">\u26a1 Quick Answer \u2014 What is Gate P Eye Drops?<\/h3>\n<p style=\"margin:0;\">Gate P Eye Drops combines Gatifloxacin 0.3% (a 4th-generation fluoroquinolone antibiotic) with Prednisolone acetate 1% (a corticosteroid) for bacterial eye infection complicated by significant inflammation. Used after cataract surgery, in bacterial blepharoconjunctivitis with marked redness, and selected post-operative regimens. Avoid in viral, fungal, or amoebic keratitis.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f6f7fb;border:1px solid #e3e5ee;border-radius:8px;padding:14px 18px;margin:18px 0;font-size:14px;line-height:1.55;\"><strong style=\"color:#1f3661;\">Why order from MedsBase?<\/strong> Sourced from a WHO-GMP certified manufacturer \u00b7 Discreet packaging \u00b7 Worldwide Shipping \u00b7 <a href=\"\/reviews\/\" rel=\"noopener\">1,400+ verified customer reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Every order is covered by our <a href=\"https:\/\/medsbase.com\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 if your parcel does not arrive within 20 business days, we reship it.<\/p>\n<h3>Why order from MedsBase<\/h3>\n<p>Gate P Eye Drops is sourced from a WHO-GMP certified manufacturer and shipped worldwide in plain, discreet packaging. Every order is covered by our <a href=\"\/medsbase-re-shipment-assurance-policy\/\" rel=\"noopener\">Reshipment Assurance Policy<\/a> \u2014 if it has not arrived after 20 business days we reship at no extra cost. Backed by 1,400+ verified customer reviews.<\/p>\n<h2>What is Gate P Eye Drops?<\/h2>\n<p>Gate P Eye Drops is manufactured by Sun Pharma \u2014 a sterile fixed combination of Gatifloxacin 0.3% and Prednisolone acetate 1% in a single ophthalmic solution. The dual mechanism kills susceptible bacterial pathogens while suppressing the inflammatory response that contributes to redness, swelling, and discomfort. Reserved for situations where both bacterial infection and clinically significant inflammation are confirmed.<\/p>\n<h2>How It Works<\/h2>\n<p>Gatifloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, the enzymes that supercoil and uncoil bacterial DNA during replication and repair. Without functional enzymes, the bacterial chromosome fragments and the cell dies. As a 4th-generation fluoroquinolone, gatifloxacin has expanded Gram-positive coverage compared with older agents and remains active against many fluoroquinolone-resistant Streptococcus and Staphylococcus strains. Prednisolone acetate binds intracellular glucocorticoid receptors and suppresses transcription of pro-inflammatory cytokines, reducing leukocyte trafficking, capillary permeability, and tissue oedema.<\/p>\n<h2>Indications<\/h2>\n<ul>\n<li><strong>Bacterial conjunctivitis with significant inflammation<\/strong> \u2014 mucopurulent discharge plus marked redness\/oedema<\/li>\n<li><strong>Bacterial blepharoconjunctivitis<\/strong><\/li>\n<li><strong>Post-cataract surgery<\/strong> \u2014 antibiotic prophylaxis bundled with steroid for inflammation control<\/li>\n<li><strong>Post-corneal-transplant regimens<\/strong> \u2014 under specialist supervision<\/li>\n<li><strong>Bacterial keratitis with corneal oedema<\/strong> \u2014 specialist setting only; combination only after culture\/diagnosis<\/li>\n<\/ul>\n<h2>Dosing<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indication<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Dose<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Bacterial conjunctivitis with inflammation<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1\u20132 drops every 4 hours while awake for 7\u201310 days<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Severe inflammation (first 24\u201348 h)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1\u20132 drops every 2 hours, then taper<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Post-cataract surgery<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">1 drop QID for 7 days, then taper over 2\u20134 weeks per surgeon<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Bacterial keratitis (specialist)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">As directed; intensive frequency may be needed<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Tapering is essential \u2014 abrupt steroid withdrawal can cause inflammatory rebound. Course length is set by the prescribing ophthalmologist; typical total exposure is 7\u201314 days, with longer regimens reserved for surgical recovery and reviewed regularly.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 16px;margin:14px 0;border-radius:4px;font-size:14px;line-height:1.55;\"><strong style=\"color:#a94442;\">Critical contraindications.<\/strong> Gate P Eye Drops is contraindicated in <strong>herpes simplex keratitis<\/strong> (steroids can devastate herpetic corneal disease \u2014 risk of corneal melt and permanent vision loss), <strong>fungal keratitis<\/strong> (steroids accelerate fungal proliferation), <strong>vaccinia, varicella, and other viral keratitis<\/strong>, and <strong>mycobacterial or amoebic eye infection<\/strong>. Always confirm bacterial diagnosis before adding the steroid component. If diagnosis is unclear, antibiotic monotherapy is safer.<\/div>\n<h2>Side Effects<\/h2>\n<p><strong>Steroid-related:<\/strong> elevated intraocular pressure (steroid response \u2014 typically appears 2+ weeks into therapy; about 30% of the population are &#8216;steroid responders&#8217;), posterior subcapsular cataract with prolonged use, delayed corneal\/conjunctival wound healing, secondary infection from immune suppression (especially fungal and herpetic).<\/p>\n<p><strong>Antibiotic-related:<\/strong> stinging or burning on instillation (most common), conjunctival hyperaemia, lid margin crusting, foreign body sensation, photophobia, rare hypersensitivity-type reactions.<\/p>\n<p><strong>Allergic reactions:<\/strong> rare but reported. Discontinue if rash, severe itching, or lid swelling develops.<\/p>\n<h2>Warnings &amp; Contraindications<\/h2>\n<ul>\n<li>Herpes simplex keratitis (dendritic \/ geographic ulcer) \u2014 absolute<\/li>\n<li>Fungal keratitis \u2014 absolute<\/li>\n<li>Varicella, vaccinia, mycobacterial, or amoebic eye disease \u2014 absolute<\/li>\n<li>Hypersensitivity to fluoroquinolones or to the corticosteroid<\/li>\n<li>Children \u2014 only with specialist supervision and IOP monitoring<\/li>\n<li>Pregnancy \/ breastfeeding \u2014 discuss with prescriber; topical absorption minimal but steroid Category C<\/li>\n<li>Open-angle glaucoma \u2014 relative contraindication; monitor IOP closely<\/li>\n<li>Prolonged use beyond 14 days \u2014 escalates all risks above<\/li>\n<li>Contact-lens wear \u2014 stop lenses for the duration of treatment<\/li>\n<\/ul>\n<h2>Storage<\/h2>\n<p>Store at 15\u201325\u00b0C protected from light. Shake before each use if the suspension formulation. Do not touch the dropper tip to your eye, lid, or any surface. Discard 28 days after first opening.<\/p>\n<h2 id=\"faqs\">Frequently Asked Questions<\/h2>\n<h3>When is Gate P Eye Drops the right choice?<\/h3>\n<p>Bacterial eye infection where inflammation is contributing significantly to symptoms \u2014 classically post-cataract surgery, post-corneal-transplant regimens, or significantly inflamed bacterial conjunctivitis confirmed by your prescriber. If unsure whether the infection is bacterial, antibiotic monotherapy is safer.<\/p>\n<h3>Why not always combine an antibiotic with a steroid?<\/h3>\n<p>Steroids mask infection signs and accelerate viral and fungal corneal disease. Adding steroid to a missed herpes simplex ulcer or fungal keratitis can blind the eye within days. Always confirm bacterial diagnosis first.<\/p>\n<h3>What is steroid response?<\/h3>\n<p>About 30% of the population have a genetic predisposition to develop elevated intraocular pressure when exposed to topical steroids. Onset is typically 2+ weeks into therapy. Your ophthalmologist should check IOP if you use topical steroid for more than 2 weeks.<\/p>\n<h3>How long can I use Gate P Eye Drops?<\/h3>\n<p>Most courses are 7\u201314 days. Post-cataract surgery regimens may extend to 4 weeks with tapering. Indefinite use risks cataract, glaucoma, and opportunistic infection. Always have a defined end-point with ophthalmology review.<\/p>\n<h3>What if my vision worsens during treatment?<\/h3>\n<p>Stop and seek same-day ophthalmology review. Worsening on antibiotic+steroid is a red flag for missed herpetic, fungal, or amoebic keratitis.<\/p>\n<h3>Is Gate P Eye Drops safe in pregnancy?<\/h3>\n<p>Topical absorption is minimal, but the steroid component carries Category C status. Discuss with your prescriber; usually possible with short courses when clearly indicated.<\/p>\n<h3>Can children use Gate P Eye Drops?<\/h3>\n<p>Only under specialist supervision with IOP monitoring. Children are particularly vulnerable to steroid-induced cataract and glaucoma.<\/p>\n<h3>What is the white precipitate I see in the eye?<\/h3>\n<p>Should be uncommon with Gatifloxacin. If you see crystalline deposits or persistent residue, contact your ophthalmologist.<\/p>\n<h3>What if I&#039;m a contact-lens user?<\/h3>\n<p>Stop lenses during treatment and for at least 24 hours after symptoms resolve. Steroid-mediated immunosuppression makes contact-lens microbial keratitis particularly dangerous.<\/p>\n<h3>What if I have a herpes simplex history?<\/h3>\n<p>Disclose this clearly to your prescriber. Steroids can reactivate dormant herpes simplex and convert minor flare-ups into vision-threatening keratitis. A different antibiotic-only regimen is safer.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3>Other Eye-Care Medications<\/h3>\n<p>Customers viewing this product also consider these alternatives in our <a href=\"\/eye-care\/\">Eye Care<\/a> range:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/pred-forte-eye-drops\/\">Pred Forte (prednisolone acetate)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/fml-eye-drop\/\">FML Eye Drop (fluorometholone)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/lotepred-eye-drop\/\">Lotepred Eye Drop (loteprednol)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/acular-ls-drop\/\">Acular LS (ketorolac)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/megabrom-eye-drop\/\">Megabrom (bromfenac)<\/a><\/li>\n<\/ul>\n<h3>Medical Disclaimer<\/h3>\n<p style=\"font-size:13px;color:#555;\">The information on this page is for educational purposes only and is not a substitute for medical advice from a qualified ophthalmologist or optometrist. Eye conditions can rapidly threaten sight \u2014 sudden vision loss, severe pain, or trauma is an ophthalmology emergency. Always consult an eye-care professional before starting, stopping, or changing any treatment.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Gate P (gatifloxacin 0.3% + prednisolone 1%) \u2014 fluoroquinolone + steroid eye drop. Bacterial conjunctivitis with inflammation; post-cataract surgery. Avoid HSV keratitis.<\/p>\n","protected":false},"featured_media":57193,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3484,3141,3343,3342],"product_tag":[4253,4254],"class_list":{"0":"post-57192","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-antibiotics","7":"product_cat-category-overview","8":"product_cat-eye-care","9":"product_cat-general-health","10":"product_tag-gate-p","11":"product_tag-gatifloxacin-prednisolone","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product\/57192","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/comments?post=57192"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media\/57193"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/media?parent=57192"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_brand?post=57192"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_cat?post=57192"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/wp-json\/wp\/v2\/product_tag?post=57192"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}