{"id":59232,"date":"2024-02-28T05:47:25","date_gmt":"2024-02-28T05:47:25","guid":{"rendered":"https:\/\/medsname.com\/sertima\/"},"modified":"2026-05-01T10:49:15","modified_gmt":"2026-05-01T10:49:15","slug":"sertima","status":"publish","type":"product","link":"https:\/\/medsbase.com\/hu\/product\/sertima\/","title":{"rendered":"Sertima"},"content":{"rendered":"

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⚡ Quick Answer — What is Sertima?<\/h3>\n
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Sertima<\/strong> tartalmaz sertraline hydrochloride (50 mg \/ 100 mg)<\/strong> from a WHO-GMP certified manufacturer (made by Intas Pharmaceuticals) — an SSRI<\/strong> with broad evidence across depression and anxiety-spectrum disorders. Standard adult dose: 50 mg naponta egyszer<\/strong> with food (range 50–200 mg\/day; titrate by 50 mg every 1–2 weeks). Onset is gradual: anxiety\/sleep often improve in 1–2 weeks; full mood response at 4–6 weeks. Common early side effects<\/strong> — nausea, loose stools, headache, jitteriness, transient insomnia or somnolence — usually subside within 7–14 days. Persistent<\/strong>: sexual dysfunction (~40%), sweating, and modest weight changes. Sertraline has the cleanest CYP profile of the SSRIs<\/strong> — weaker CYP2D6 inhibition than paroxetine or fluoxetine, making it a sensible choice in patients on multiple medicines.<\/p>\n<\/div>\n

\nMit kapsz a MedsBase-n\u00e1l:<\/strong> WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3 \u00b7 Diszkr\u00e9t csomagol\u00e1s \u00b7 Vil\u00e1gszerte sz\u00e1ll\u00edt\u00e1s \u00b7 1.400+ hiteles\u00edtett v\u00e1s\u00e1rl\u00f3i v\u00e9lem\u00e9ny<\/a>\n<\/div>\n

\ud83d\udce6 Minden rendel\u00e9st fedez a \u00dajrak\u00fcld\u00e9si Garancia<\/strong><\/a> \u2014 ha a csomagod nem \u00e9rkezik meg 20 munkanapon bel\u00fcl, \u00fajrak\u00fcldj\u00fck.<\/p>\n

Mi\u00e9rt rendelj a MedsBase-r\u00f3l<\/h3>\n

Generikus gy\u00f3gyszereink WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3kt\u00f3l sz\u00e1rmaznak, \u00e9s diszkr\u00e9t, egyszer\u0171 csomagol\u00e1sban sz\u00e1ll\u00edtjuk \u0151ket vil\u00e1gszerte \u2014 a csomagon nem szerepel a gy\u00f3gyszer neve. A k\u00e1rty\u00e1s fizet\u00e9sek egy szab\u00e1lyozott feldolgoz\u00f3n kereszt\u00fcl t\u00f6rt\u00e9nnek (a sz\u00e1mlale\u00edr\u00e1sok egy szab\u00e1lyozott k\u00e1rtyafizet\u00e9si feldolgoz\u00f3t tartalmaznak \u2014 soha nem \u201cMedsBase\u201d vagy b\u00e1rmilyen gy\u00f3gyszer neve). Kriptovalut\u00e1t \u00e9s SEPA banki \u00e1tutal\u00e1st is elfogadunk. Minden rendel\u00e9st a Reshipment Assurance Policy biztos\u00edt\u00e9k fedez.<\/p>\n<\/div>\n

Important — this is not a situational-anxiety medication.<\/strong> Sertima is a szerotonin visszav\u00e9tel-g\u00e1tl\u00f3 (SSRI)<\/strong>, prescribed and titrated over weeks for major depressive disorder (MDD), obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD)<\/strong>. It is nem<\/strong> the right drug for acute, performance-related anxiety (flying, public speaking, exams) — for those use cases beta-blockers (propranolol), benzodiazepines, or hydroxyzine are clinically appropriate. If you do not have a diagnosed mood, anxiety, or psychiatric disorder, do not start this medication.<\/div>\n
FDA black-box warning — suicidality.<\/strong> All antidepressants carry an FDA black-box warning for increased risk of suicidal thinking and behaviour in children, adolescents, and young adults under 25, particularly during the first weeks of treatment or after dose changes. Family members and prescribers should monitor closely for worsening mood, agitation, or suicidal ideation in this age group.<\/div>\n

What Is Sertima?<\/h2>\n

Sertima is an oral tablet of sertraline hydrochloride (50 mg \/ 100 mg)<\/strong> manufactured by Intas Pharmaceuticals under WHO-GMP certification. Sertraline (brand name Zoloft<\/strong> in the US, Lustral<\/strong> in the UK) is a szerotonin visszav\u00e9tel-g\u00e1tl\u00f3 (SSRI)<\/strong> launched by Pfizer in 1991 and one of the most-prescribed antidepressants worldwide. It selectively blocks the presynaptic serotonin transporter (SERT), increasing synaptic serotonin available to bind to postsynaptic 5-HT receptors over weeks of treatment.<\/p>\n

Sertraline is a first-line treatment recommendation in NICE, APA, and WFSBP guidelines for major depression in adults and the FDA-approved first-line SSRI for paediatric OCD (age ≥ 6).<\/p>\n

J\u00f3v\u00e1hagyott indik\u00e1ci\u00f3k<\/h2>\n
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  • Major depressive disorder (MDD)<\/strong> in adults; sertraline-paroxetine and sertraline-mirtazapine combinations are commonly used in treatment-resistant depression.<\/li>\n
  • K\u00e9nyszerbetegs\u00e9g (OCD)<\/strong> in adults and children aged 6+; doses typically titrated higher than for MDD (100–200 mg\/day).<\/li>\n
  • P\u00e1nikzavar<\/strong> with or without agoraphobia; start lower (12.5–25 mg) to avoid early panic exacerbation.<\/li>\n
  • Social anxiety disorder (social phobia)<\/strong> — chronic \/ generalised type, not performance-only.<\/li>\n
  • Poszttraum\u00e1s stressz zavar (PTSD)<\/strong> — one of two FDA-approved SSRIs for this indication (with paroxetine).<\/li>\n
  • Premenstrual dysphoric disorder (PMDD)<\/strong> — can be dosed continuously or only luteal-phase (cycle days 14–28).<\/li>\n<\/ul>\n

    Standard Dosing by Indication<\/h2>\n\n\n\n\n\n\n\n\n\n
    Agoprex is a 25 mg agomelatine tablet supplied by Sun Pharma. Agomelatine is mechanistically unique among antidepressants: it acts as an agonist at melatonin MT1 and MT2 receptors and an antagonist at 5-HT2C serotonin receptors. The dual mechanism resynchronises disrupted circadian rhythms (a feature of major depression) while indirectly increasing dopamine and noradrenaline release in the frontal cortex.<\/th>\nKezel\u00e9s ind\u00edt\u00e1sa<\/th>\nIndications and dosing<\/th>\nTitr\u00e1l\u00e1s<\/th>\n<\/tr>\n<\/thead>\n
    MDD, social anxiety, PTSD, PMDD<\/td>\n50 mg once daily with food<\/td>\n50–200 mg\/day<\/td>\nIncrease by 50 mg every 1–2 weeks if tolerated and partial response<\/td>\n<\/tr>\n
    P\u00e1nikzavar<\/td>\n12.5–25 mg\/day × 1 week<\/td>\n50–200 mg\/day<\/td>\nSlower up-titration to minimise early jitteriness and panic exacerbation<\/td>\n<\/tr>\n
    OCD (adult)<\/td>\n50 mg naponta egyszer<\/td>\n100–200 mg\/day<\/td>\nOften requires the upper end of the dose range; allow 8–12 weeks for response assessment<\/td>\n<\/tr>\n
    OCD (paediatric 6–12 y)<\/td>\n25 mg naponta egyszer<\/td>\n25–200 mg\/day<\/td>\nUp-titrate slowly; weight-based caps in younger children<\/td>\n<\/tr>\n
    M\u00e1jk\u00e1rosod\u00e1s<\/td>\n25 mg naponta egyszer<\/td>\nUp to 100 mg with care<\/td>\nReduced clearance — use the lowest effective dose<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Mell\u00e9khat\u00e1sok<\/h2>\n

    Common, persistent, and rare side effects<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
    Gyakoris\u00e1g<\/th>\nHat\u00e1s<\/th>\nNotes \/ management<\/th>\n<\/tr>\n<\/thead>\n
    Common (>10%)<\/td>\nNausea, diarrhoea, loose stools<\/td>\nTake with food; usually subsides within 1–2 weeks<\/td>\n<\/tr>\n
    Gyakori<\/td>\n\u00c1lmatlans\u00e1g vagy \u00e1lmoss\u00e1g<\/td>\nVariable — if activating, dose in the morning; if sedating, dose at bedtime<\/td>\n<\/tr>\n
    Gyakori<\/td>\nFejf\u00e1j\u00e1s, sz\u00e9d\u00fcl\u00e9s<\/td>\nAdequate hydration; usually transient<\/td>\n<\/tr>\n
    Gyakori<\/td>\nSzexu\u00e1lis diszfunkci\u00f3 (k\u00e9sleltetett orgazmus, cs\u00f6kkent libid\u00f3)<\/td>\nPersistent in up to 40%; consider drug holiday, dose reduction, or switch to bupropion \/ mirtazapine if intolerable<\/td>\n<\/tr>\n
    Gyakori<\/td>\nIzzad\u00e1s, sz\u00e1jsz\u00e1razs\u00e1g<\/td>\nPersistent low-grade nuisance<\/td>\n<\/tr>\n
    Kevesebb gyakoris\u00e1g\u00fa<\/td>\nWeight gain (modest, +1–3 kg over months)<\/td>\nLess than paroxetine or mirtazapine<\/td>\n<\/tr>\n
    Kevesebb gyakoris\u00e1g\u00fa<\/td>\nBruising, GI bleeding<\/td>\nSSRIs reduce platelet serotonin uptake; caution with NSAIDs \/ anticoagulants<\/td>\n<\/tr>\n
    Ritka<\/td>\nHyponatraemia (SIADH)<\/td>\nOlder adults at greatest risk; check Na+ if confusion or seizure<\/td>\n<\/tr>\n
    Ritka<\/td>\nSzerotonin szindr\u00f3ma<\/td>\nSee drug interactions section<\/td>\n<\/tr>\n
    Ritka<\/td>\nQT prolongation at high dose<\/td>\nDocument baseline ECG in patients with cardiac risk<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Gy\u00f3gyszerk\u00f6lcs\u00f6nhat\u00e1sok<\/h2>\n

    Absolute contraindications<\/strong>: monoamine oxidase inhibitors (MAOIs) including selegiline, rasagiline, linezolid (an antibiotic with MAOI activity), methylene blue — allow 14 nap<\/strong> washout before or after sertraline. Concurrent pimozide is contraindicated due to QT risk.<\/p>\n

    Serotonin syndrome risk — combine with caution and only under prescriber direction<\/strong>: triptans (sumatriptan, rizatriptan), tramadol, pethidine (meperidine), dextromethorphan, St John’s wort, lithium, other serotonergic antidepressants.<\/p>\n

    Bleeding risk — combine with caution<\/strong>: NSAIDs, aspirin, warfarin, DOACs — SSRIs reduce platelet serotonin uptake.<\/p>\n

    Plasma-level shifts<\/strong>: sertraline mildly inhibits CYP2D6 (less than paroxetine \/ fluoxetine) — modest interaction with metoprolol, codeine, tamoxifen, atomoxetine.<\/p>\n

    Discontinuation Syndrome<\/h2>\n

    Sertraline has a moderate-half-life (~26 h)<\/strong> — discontinuation symptoms are milder than paroxetine or venlafaxine but real<\/strong>. Symptoms (FINISH mnemonic): Flu-like aches, Insomnia, Nausea, Imbalance \/ dizziness, Sensory disturbance (the “brain zaps”), Hyperarousal. Typically begin 2–4 days after a missed dose or abrupt stop and resolve in 1–3 weeks. Taper<\/strong>: reduce by 25–50 mg every 2–4 weeks; for long-term users (> 12 months), taper more slowly using hyperbolic step-downs to avoid prolonged withdrawal.<\/p>\n

    Terhess\u00e9g \u00e9s szoptat\u00e1s<\/h2>\n

    Sertraline is one of the preferred SSRIs in pregnancy<\/strong> when antidepressant treatment is indicated — the largest registry data and ACOG guidance support continued use in moderate-to-severe MDD. Late-third-trimester exposure carries a small risk of neonatal adaptation syndrome<\/strong> (jitteriness, feeding difficulties — usually resolves within 1–2 weeks). Sertraline transfers minimally into breast milk and is the preferred SSRI in breastfeeding<\/strong>.<\/p>\n

    Choosing Sertraline vs Other SSRIs<\/h2>\n

    Compared with other commonly-used SSRIs<\/h2>\n\n\n\n\n\n\n\n\n
    Gy\u00f3gyszer<\/th>\nNotable strengths<\/th>\nNotable weaknesses<\/th>\n<\/tr>\n<\/thead>\n
    Sertraline<\/td>\nCleanest CYP profile; preferred in pregnancy \/ breastfeeding; broad indications<\/td>\nGI side effects more prominent at start<\/td>\n<\/tr>\n
    Paroxetine (Xepar)<\/td>\nGood for GAD and panic; sedating — helpful with insomnia<\/td>\nWorst discontinuation syndrome; weight gain; pregnancy category D<\/td>\n<\/tr>\n
    Escitalopram<\/td>\nCleanest tolerability; well-studied for GAD<\/td>\nDose-dependent QT prolongation; max 20 mg, 10 mg in elderly<\/td>\n<\/tr>\n
    Fluoxetine<\/td>\nLong half-life cushions discontinuation; activating<\/td>\nCYP2D6 inhibition; takes longer to wash out for switches<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Gyakran Ism\u00e9telt K\u00e9rd\u00e9sek<\/h2>\n

    How long does Sertima take to work?<\/h3>\n

    Anxiety, sleep, and somatic symptoms often improve within 1–2 weeks. Full mood response in MDD typically appears at 4–6 weeks. OCD often requires 8–12 weeks at the upper dose range. Do not judge effectiveness before 6 weeks at an adequate dose.<\/p>\n

    Can I stop Sertima once I feel better?<\/h3>\n

    For a first episode of MDD, guidelines recommend continuing for at least 6–9 months after remission. For recurrent MDD or chronic anxiety, longer courses (1–2+ years) are common. Always taper rather than stop abruptly.<\/p>\n

    Will Sertima cause weight gain?<\/h3>\n

    Sertraline causes only modest weight gain over months — far less than paroxetine or mirtazapine. Some patients lose weight initially due to GI side effects.<\/p>\n

    Does Sertima cause sexual side effects?<\/h3>\n

    Yes — SSRIs as a class can cause delayed orgasm, reduced libido, and erectile difficulty in around 40% of users. If persistent and bothersome, options include dose reduction, drug holidays (with prescriber input), or switching to bupropion or mirtazapine.<\/p>\n

    Can I drink alcohol on Sertima?<\/h3>\n

    Light, occasional alcohol is generally tolerated, but alcohol worsens depression and anxiety, increases sedation, and is implicated in disinhibited or impulsive behaviour during the first weeks of treatment. Avoid heavy use.<\/p>\n

    Mi t\u00f6rt\u00e9nik, ha kihagyok egy adagot?<\/h3>\n

    Take it as soon as you remember unless it is close to the next dose — never double up. Missing a single dose rarely causes problems given sertraline’s 26-hour half-life.<\/p>\n

    Is Sertima safe in pregnancy?<\/h3>\n

    Sertraline is one of the preferred SSRIs when antidepressant treatment is needed in pregnancy. Discuss benefit and risk individually with the prescriber, especially in the first trimester and around delivery.<\/p>\n

    Can Sertima be combined with other antidepressants?<\/h3>\n

    Combinations (e.g. with mirtazapine in “California rocket fuel”) are used in treatment-resistant depression but only under prescriber direction. Combining with MAOIs, linezolid, methylene blue, or excessive serotonergic agents (triptans, tramadol, St John’s wort) risks serotonin syndrome.<\/p>\n

    How is Sertima different from Sertima alternatives like Sertima or Zosert?<\/h3>\n

    All sertraline brands are pharmacologically identical at the molecule level. Brand differences come down to manufacturer, tablet appearance, excipients, and pricing. We supply WHO-GMP certified Indian generics across multiple brand names so customers can pick what is in stock.<\/p>\n

    How should Sertima be stored?<\/h3>\n

    Store at 15–30 °C in the original blister packaging, away from moisture and direct sunlight. Keep out of reach of children — sertraline overdose, while less dangerous than TCAs, is medically significant.<\/p>\n

    Orvosi felel\u0151ss\u00e9gi nyilatkozat:<\/strong> Information on this page is intended for adults using prescribed psychiatric medication and is not a substitute for individualised medical care. Antidepressants, antipsychotics, and related medications can interact with other drugs, alcohol, and pre-existing conditions. Discuss any new medication, dose change, or planned discontinuation with a qualified prescriber. If you experience suicidal thoughts, mania, severe akathisia, signs of serotonin syndrome (high fever, confusion, muscle rigidity, rapid heart rate), or neuroleptic malignant syndrome, seek emergency care immediately.<\/div>\n

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    Kapcsol\u00f3d\u00f3 alternat\u00edv\u00e1k<\/h3>\n

    Egy\u00e9b term\u00e9kek a Kr\u00f3nikus betegs\u00e9gek<\/strong> v\u00e1s\u00e1rl\u00f3k \u00e1ltal szint\u00e9n megtekintett term\u00e9kek:<\/p>\n