{"id":59417,"date":"2024-02-28T05:57:20","date_gmt":"2024-02-28T05:57:20","guid":{"rendered":"https:\/\/medsname.com\/nilol\/"},"modified":"2026-05-01T10:49:15","modified_gmt":"2026-05-01T10:49:15","slug":"nilol","status":"publish","type":"product","link":"https:\/\/medsbase.com\/hu\/product\/nilol\/","title":{"rendered":"Nilol"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h2 id=\"faqs\">Gyakran Ism\u00e9telt K\u00e9rd\u00e9sek<\/h2>\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Nilol?<\/h3>\n<p style=\"margin:0;\"><strong>Nilol<\/strong> egy <strong>fixed-dose combination of atenolol (beta-blocker) + nifedipine (dihydropyridine calcium-channel blocker)<\/strong> from a WHO-GMP certified manufacturer &mdash; widely prescribed in India and the subcontinent for combined hypertension and angina, particularly in patients where a single-drug regimen has failed. The two drugs work via complementary mechanisms: atenolol reduces cardiac output and heart rate (beta-1 blockade); nifedipine causes direct arterial vasodilation via L-type calcium channel blockade. The beta-blocker blunts the reflex tachycardia that bare nifedipine would otherwise produce. Typical dose: <strong>napi egyszer egy tabletta<\/strong>. Contraindications inherit from both components: <strong>asthma \/ severe COPD \/ second-third degree heart block \/ acute heart failure \/ severe aortic stenosis \/ recent MI \/ cardiogenic shock<\/strong>.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Mit kapsz a MedsBase-n\u00e1l:<\/strong> WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3 \u00b7 Diszkr\u00e9t csomagol\u00e1s \u00b7 Vil\u00e1gszerte sz\u00e1ll\u00edt\u00e1s \u00b7 1.400+ hiteles\u00edtett <a href=\"https:\/\/medsbase.com\/hu\/reviews\/\">v\u00e1s\u00e1rl\u00f3i v\u00e9lem\u00e9ny<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Minden rendel\u00e9st fedez a <a href=\"https:\/\/medsbase.com\/hu\/medsbase-re-shipment-assurance-policy\/\"><strong>\u00dajrak\u00fcld\u00e9si Garancia<\/strong><\/a> \u2014 ha a csomagod nem \u00e9rkezik meg 20 munkanapon bel\u00fcl, \u00fajrak\u00fcldj\u00fck.<\/p>\n<h3>Mi\u00e9rt rendelj a MedsBase-r\u00f3l<\/h3>\n<p>Generikus gy\u00f3gyszereink WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3kt\u00f3l sz\u00e1rmaznak, \u00e9s diszkr\u00e9t, egyszer\u0171 csomagol\u00e1sban sz\u00e1ll\u00edtjuk \u0151ket vil\u00e1gszerte \u2014 a csomagon nem szerepel a gy\u00f3gyszer neve. A k\u00e1rty\u00e1s fizet\u00e9sek egy szab\u00e1lyozott feldolgoz\u00f3n kereszt\u00fcl t\u00f6rt\u00e9nnek (a sz\u00e1mlale\u00edr\u00e1sok egy szab\u00e1lyozott k\u00e1rtyafizet\u00e9si feldolgoz\u00f3t tartalmaznak \u2014 soha nem \u201cMedsBase\u201d vagy b\u00e1rmilyen gy\u00f3gyszer neve). Kriptovalut\u00e1t \u00e9s SEPA banki \u00e1tutal\u00e1st is elfogadunk. Minden rendel\u00e9st a Reshipment Assurance Policy biztos\u00edt\u00e9k fedez.<\/p>\n<h2 class=\"wp-block-heading\">What Is Nilol?<\/h2>\n<p>Nilol is an oral tablet from a WHO-GMP certified manufacturer containing:<\/p>\n<ul>\n<li><strong>Atenolol 50 mg<\/strong> &mdash; a cardioselective beta-1 blocker (the same molecule in <a href=\"https:\/\/medsbase.com\/hu\/atenheal\/\">Atenheal<\/a>)<\/li>\n<li><strong>Nifedipine 20 mg<\/strong> &mdash; a dihydropyridine calcium-channel blocker (extended-release; same molecule in <a href=\"https:\/\/medsbase.com\/hu\/depin\/\">Depin<\/a>, <a href=\"https:\/\/medsbase.com\/hu\/nicardia-retard\/\">Nicardia Retard<\/a>)<\/li>\n<\/ul>\n<p>The combination originated in 1980s European cardiology (brand Tenif, Tenoretic) and remains popular in India for patients with both hypertension and stable angina. The two drugs target different mechanisms: atenolol for heart-rate and contractility reduction; nifedipine for direct arterial vasodilation. The beta-blocker prevents the reflex tachycardia that nifedipine monotherapy would otherwise cause.<\/p>\n<h2 class=\"wp-block-heading\">How Nilol Works<\/h2>\n<ul>\n<li><strong>Atenolol<\/strong> &mdash; beta-1 blockade in the SA node reduces heart rate; blockade in ventricular myocardium reduces contractility. Lower cardiac output = lower blood pressure; lower myocardial oxygen demand = less angina.<\/li>\n<li><strong>Nifedipin<\/strong> &mdash; L-type calcium channel blockade in arterial smooth muscle causes direct arterial dilation. Reduces systemic vascular resistance and coronary vasospasm.<\/li>\n<li><strong>Kieg\u00e9sz\u00edt\u0151 p\u00e1ros\u00edt\u00e1s<\/strong> &mdash; bare nifedipine would cause reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control without the palpitation side effect.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Alkalmaz\u00e1s \u00e9s adagol\u00e1s<\/h2>\n<ul>\n<li><strong>Combined hypertension + stable angina<\/strong> \u2014 els\u0151dleges indik\u00e1ci\u00f3<\/li>\n<li><strong>Rezisztens hypertonia<\/strong> &mdash; step-up therapy when single-agent has failed<\/li>\n<li><strong>Hypertension with coronary artery disease<\/strong><\/li>\n<\/ul>\n<p><strong>Adagol\u00e1s:<\/strong> one tablet once daily, usually morning. Maximum 2 tablets\/day. Target BP &lt;140\/90 (or &lt;130\/80 with comorbidity).<\/p>\n<p><strong>Monitoroz\u00e1s:<\/strong> baseline + periodic ECG (atenolol bradycardia \/ nifedipine effect on PR interval), pulse, BP, peripheral oedema (nifedipine commonly causes ankle swelling).<\/p>\n<h2 class=\"wp-block-heading\">Mell\u00e9khat\u00e1sok<\/h2>\n<p><strong>Atenolol-related:<\/strong> fatigue, cold extremities, bradycardia, exercise intolerance, mild fatigue, erectile dysfunction, masked hypoglycaemia in diabetics.<\/p>\n<p><strong>Nifedipine-related:<\/strong><\/p>\n<ul>\n<li><strong>L\u00e1bsz\u00edvarced\u00e9s<\/strong> (peripheral swelling) &mdash; dose-related; occurs in up to 25% of long-term users<\/li>\n<li>Flushing, headache (vasodilation)<\/li>\n<li>Gingival hyperplasia (gum overgrowth)<\/li>\n<li>Sz\u00e9kreked\u00e9s<\/li>\n<li>Hot flashes, particularly at onset of therapy<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Ellenjavallatok<\/h2>\n<ul>\n<li>Asthma \/ severe COPD (atenolol component)<\/li>\n<li>Second\/third-degree heart block, sinus bradycardia &lt;50, sick sinus syndrome<\/li>\n<li>Acute decompensated heart failure, cardiogenic shock<\/li>\n<li>Severe aortic stenosis (nifedipine can worsen)<\/li>\n<li>Recent myocardial infarction, unstable angina (short-acting nifedipine concern; the ER form is safer)<\/li>\n<li>Severe renal impairment (eGFR &lt;15 &mdash; atenolol dose reduction needed; prefer non-renally-cleared beta-blocker)<\/li>\n<li>Pregnancy (both components)<\/li>\n<li>Hyperszenzitivit\u00e1s b\u00e1rmely komponensre<\/li>\n<\/ul>\n<h2>T\u00e1rol\u00e1s<\/h2>\n<p>Store below 25&deg;C; protect from light.<\/p>\n<h3 class=\"wp-block-heading\">Why combine atenolol with nifedipine?<\/h3>\n<p>Complementary mechanisms and side-effect-mitigation. Bare nifedipine causes reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control. For patients with both hypertension AND stable angina, the two drugs target both diseases simultaneously.<\/p>\n<h3 class=\"wp-block-heading\">What about the ankle swelling from nifedipine?<\/h3>\n<p>Dose-related peripheral oedema occurs in up to 25% of long-term nifedipine users. It is NOT from fluid overload &mdash; it is from pre-capillary vasodilation increasing hydrostatic pressure in the lower legs. Treatment: dose reduction, leg elevation, compression stockings, or switch to a non-dihydropyridine CCB (verapamil, diltiazem) or a different vasodilator class (ACE inhibitor, ARB).<\/p>\n<h3 class=\"wp-block-heading\">Why not use this in pregnancy?<\/h3>\n<p>Atenolol is associated with intrauterine growth restriction in pregnancy (more so than other beta-blockers) and neonatal bradycardia\/hypoglycaemia. For antihypertensive use in pregnancy, <a href=\"https:\/\/medsbase.com\/hu\/labebet\/\">labetalol<\/a>, methyldopa, and nifedipine-monotherapy (not this FDC) are the preferred options.<\/p>\n<h3 class=\"wp-block-heading\">Where can I buy Nilol online?<\/h3>\n<p>You can buy Nilol (atenolol + nifedipine 50 mg + 20 mg, 30-180 tablets) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n<h2 class=\"wp-block-heading\">Kapcsol\u00f3d\u00f3 b\u00e9ta-blokkol\u00f3k \u00e9s antihipertenz\u00edvek<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/hu\/beloc\/\">Beloc \u2014 Propranolol 10\/20\/40 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/betapro-sr\/\">Betapro SR \u2014 Propranolol 80 mg SR<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/metolar\/\">Metolar \u2014 Metoprolol-tartar\u00e1t 25\/50\/100 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/metomac\/\">Metomac \u2014 Metoprolol 25 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/p-nolol\/\">P-Nolol \u2014 Propranolol 20\/40 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/topme\/\">Topme \u2014 Metoprolol 50 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/high-blood-pressure-medication\/\"><strong>\u00d6sszes magas v\u00e9rnyom\u00e1sra szolg\u00e1l\u00f3 gy\u00f3gyszer b\u00f6ng\u00e9sz\u00e9se<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 Orvosi nyilatkozat.<\/strong> Ez az oldal t\u00e1j\u00e9koztat\u00f3 jelleg\u0171, \u00e9s nem helyettes\u00edti a k\u00e9pzett eg\u00e9szs\u00e9g\u00fcgyi szakember tan\u00e1cs\u00e1t. A hypertonia, sz\u00edvel\u00e9gtelens\u00e9g \u00e9s sz\u00edvritmuszavarok diagnosztiz\u00e1l\u00e1st, monitoroz\u00e1st \u00e9s d\u00f3zis-individualiz\u00e1l\u00e1st ig\u00e9nyelnek orvosi r\u00e9sz\u00e9r\u0151l \u2014 mindig orvosi utas\u00edt\u00e1s szerint haszn\u00e1ljon b\u00e9ta-blokkol\u00f3kat.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Kapcsol\u00f3d\u00f3 alternat\u00edv\u00e1k<\/h3>\n<p>Egy\u00e9b term\u00e9kek a <strong>Kr\u00f3nikus betegs\u00e9gek<\/strong> v\u00e1s\u00e1rl\u00f3k \u00e1ltal szint\u00e9n megtekintett term\u00e9kek:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/hu\/gtn-spray\/\">GTN Spray<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/vilano\/\">Vilano<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/symbicort-turbohaler\/\">Symbicort Turbohaler<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/olmezest-am\/\">Olmezest AM<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/cosart\/\">Cosart<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Nilol is a fixed-dose combination of atenolol 50 mg + nifedipine 20 mg \u2014 beta-blocker plus dihydropyridine calcium-channel blocker for combined hypertension and stable angina. Complementary mechanisms; atenolol blocks reflex tachycardia from nifedipine vasodilation. Once daily, morning. Not for pregnancy.<\/p>","protected":false},"featured_media":59418,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260,3356],"product_tag":[3365,3390,4693],"class_list":{"0":"post-59417","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_cat-high-blood-pressure-medication","10":"product_tag-atenolol","11":"product_tag-nifedipine","12":"product_tag-nilol","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product\/59417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/comments?post=59417"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/media\/59418"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/media?parent=59417"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product_brand?post=59417"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product_cat?post=59417"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product_tag?post=59417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}