{"id":60412,"date":"2024-02-28T06:47:45","date_gmt":"2024-02-28T06:47:45","guid":{"rendered":"https:\/\/medsname.com\/rasalect\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"rasalect","status":"publish","type":"product","link":"https:\/\/medsbase.com\/hu\/product\/rasalect\/","title":{"rendered":"Rasalect"},"content":{"rendered":"

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\u26a1 Gyors v\u00e1lasz<\/h3>\n

Rasalect<\/strong> or\u00e1lis rasagiline<\/strong> (1 mg) tablet \u2014 a selective monoamin-oxid\u00e1z-B (MAO-B) g\u00e1tl\u00f3<\/strong> 2-es t\u00edpus\u00fa diabetes kezel\u00e9s\u00e9re haszn\u00e1lj\u00e1k Parkinson-k\u00f3r<\/strong>. By blocking MAO-B in the brain, it slows the breakdown of dopamine and helps lengthen the time levodopa keeps working between doses (reduces “off” time). Unlike selegiline, rasagiline is nem<\/em> metabolised to amphetamine derivatives, so insomnia is much less of a problem. Common side effects: insomnia, headache, dyskinesia, dry mouth, postural hypotension. Fontos:<\/strong> ker\u00fclje a legt\u00f6bb antidepressz\u00e1nssal (SSRI-k, SNRI-k, TCA-k), opioidokkal, mint p\u00e9ld\u00e1ul a pethidin \u00e9s a tramadol, valamint a dextrometorf\u00e1nnal val\u00f3 kombin\u00e1l\u00e1s\u00e1t \u2014 kock\u00e1zata a szerotonin szindr\u00f3ma<\/em>.<\/p>\n<\/div>\n

\nMit kapsz a MedsBase-n\u00e1l:<\/strong> WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3 \u00b7 Diszkr\u00e9t csomagol\u00e1s \u00b7 Vil\u00e1gszerte sz\u00e1ll\u00edt\u00e1s \u00b7 1.400+ hiteles\u00edtett v\u00e1s\u00e1rl\u00f3i v\u00e9lem\u00e9ny<\/a>\n<\/div>\n

\ud83d\udce6 Minden rendel\u00e9st fedez a \u00dajrak\u00fcld\u00e9si Garancia<\/strong><\/a> \u2014 ha a csomagod nem \u00e9rkezik meg 20 munkanapon bel\u00fcl, \u00fajrak\u00fcldj\u00fck.<\/p>\n

Mi\u00e9rt rendelj a MedsBase-r\u00f3l<\/h3>\n

Generikus gy\u00f3gyszereink WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3kt\u00f3l sz\u00e1rmaznak, \u00e9s diszkr\u00e9t, egyszer\u0171 csomagol\u00e1sban sz\u00e1ll\u00edtjuk \u0151ket vil\u00e1gszerte \u2014 a csomagon nem szerepel a gy\u00f3gyszer neve. A k\u00e1rty\u00e1s fizet\u00e9sek egy szab\u00e1lyozott feldolgoz\u00f3n kereszt\u00fcl t\u00f6rt\u00e9nnek (a sz\u00e1mlale\u00edr\u00e1sok egy szab\u00e1lyozott k\u00e1rtyafizet\u00e9si feldolgoz\u00f3t tartalmaznak \u2014 soha nem \u201cMedsBase\u201d vagy b\u00e1rmilyen gy\u00f3gyszer neve). Kriptovalut\u00e1t \u00e9s SEPA banki \u00e1tutal\u00e1st is elfogadunk. Minden rendel\u00e9st a Reshipment Assurance Policy biztos\u00edt\u00e9k fedez.<\/p>\n

What Is Rasalect?<\/h2>\n

Rasalect is an oral tablet containing rasagiline 1 mg<\/strong>. rasagiline is a selective monoamin-oxid\u00e1z-B (MAO-B) g\u00e1tl\u00f3<\/strong> eredetileg Azilect<\/strong>. Rasalect is manufactured by a WHO-GMP certified facility and is bioequivalent to the originator brand at the same strength.<\/p>\n

Rasagiline was developed as a second-generation MAO-B inhibitor specifically to avoid selegiline’s amphetamine metabolites. It has a clean active metabolite (aminoindan) which itself has neuroprotective properties in laboratory models. Rasagiline can be used as monotherapy in early Parkinson disease or as adjunct to levodopa for end-of-dose wearing-off.<\/p>\n

How Does Rasalect (rasagiline) Work?<\/h2>\n

Rasagiline irreversibly inactivates MAO-B in the brain, slowing the breakdown of dopamine. Like selegiline it is selective for MAO-B at therapeutic doses (1 mg\/day) but loses selectivity above 1.5–2 mg\/day. Its main metabolite, aminoindan, has its own potential neuroprotective activity in preclinical models — the basis for the ADAGIO disease-modification trial, which produced suggestive but not conclusive results.<\/p>\n

Az MAO-B g\u00e1tl\u00f3k \u00f6sszehasonl\u00edt\u00e1sa<\/h2>\n

A Parkinson-k\u00f3r kezel\u00e9s\u00e9ben haszn\u00e1lt h\u00e1rom MAO-B g\u00e1tl\u00f3 \u2014 szelegilin, raszagilin \u00e9s safinamid \u2014 k\u00f6z\u00f6s mechanizmus\u00fa, de jelent\u0151sen elt\u00e9rnek a metabolitjaik, adagol\u00e1suk \u00e9s klinikai pozicion\u00e1l\u00e1suk tekintet\u00e9ben:<\/p>\n\n\n\n\n\n\n\n\n\n
Jellemz\u0151<\/th>\nSzelegilin<\/th>\nRaszagilin<\/th>\nSafinamid<\/th>\n<\/tr>\n<\/thead>\n
Tipikus adag<\/td>\n5\u201310 mg\/nap<\/td>\n0,5\u20131 mg\/nap<\/td>\n50\u2013100 mg\/nap<\/td>\n<\/tr>\n
Akt\u00edv metabolitok<\/td>\nAmfetamin + metamfetamin<\/td>\nAminoind\u00e1n (nem amfetamin-szer\u0171)<\/td>\nNincs akt\u00edv stimul\u00e1ns metabolit<\/td>\n<\/tr>\n
Glutam\u00e1t-hat\u00e1s<\/td>\nNem<\/td>\nNem<\/td>\nIgen<\/strong> \u2014 n\u00e1triumcsatorna\/glutam\u00e1t-felszabadul\u00e1s modul\u00e1ci\u00f3<\/td>\n<\/tr>\n
Agoprex is a 25 mg agomelatine tablet supplied by Sun Pharma. Agomelatine is mechanistically unique among antidepressants: it acts as an agonist at melatonin MT1 and MT2 receptors and an antagonist at 5-HT2C serotonin receptors. The dual mechanism resynchronises disrupted circadian rhythms (a feature of major depression) while indirectly increasing dopamine and noradrenaline release in the frontal cortex.<\/td>\nMonoter\u00e1pia vagy kieg\u00e9sz\u00edt\u0151 kezel\u00e9s<\/td>\nMonoter\u00e1pia vagy kieg\u00e9sz\u00edt\u0151 kezel\u00e9s<\/td>\nCsak kieg\u00e9sz\u00edt\u0151 kezel\u00e9sk\u00e9nt<\/strong> \u2014 levodop\u00e1n szenved\u0151, fluktu\u00e1l\u00f3 PD eset\u00e9n<\/td>\n<\/tr>\n
\u00c1lmatlans\u00e1g kock\u00e1zata<\/td>\nMagasabb (amfetamin metabolitok)<\/td>\nAlacsony<\/td>\nAlacsony<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Who Is Rasalect For?<\/h2>\n

Rasalect is appropriate for adults with Parkinson disease — either as monotherapy in early disease or as adjunct to levodopa in patients with motor fluctuations. Compared with selegiline, rasagiline is preferred when insomnia is a concern. Compared with safinamide, rasagiline is the better monotherapy option (safinamide is licensed only as adjunct).<\/p>\n

D\u00f3zis \u00e9s alkalmaz\u00e1s<\/h2>\n

A szok\u00e1sos feln\u0151tt adag 1 mg naponta egyszer<\/strong>, taken in the morning with or without food. There is no need for titration — full effect is reached within 1–2 weeks. Doses above 1 mg\/day are generally avoided as MAO-B selectivity is lost. In moderate hepatic impairment reduce to 0.5 mg\/day; in severe hepatic impairment avoid.<\/p>\n\n\n\n\n\n\n\n
Popul\u00e1ci\u00f3<\/th>\nDose<\/th>\n<\/tr>\n<\/thead>\n
Standard adult<\/td>\n1 mg once daily, morning<\/td>\n<\/tr>\n
Enyhe m\u00e1jk\u00e1rosod\u00e1s<\/td>\n0.5 mg once daily<\/td>\n<\/tr>\n
Moderate-severe hepatic impairment<\/td>\nKer\u00fclje<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
\u26a0 Tiramin \u00e9s a \u201csajt hat\u00e1s\u201d<\/strong> Szabv\u00e1nyos MAO-B szelekt\u00edv adagokn\u00e1l \u00e1ltal\u00e1ban sz\u00fcks\u00e9ges nem<\/em> a tiraminban gazdag \u00e9telek korl\u00e1toz\u00e1sa. Azonban az MAO-B szelektivit\u00e1s adagf\u00fcgg\u0151 \u2013 a szelgilin 10 mg\/nap, a razagilin 1 mg\/nap, a szafinamid pedig 100 mg\/nap felett vesz\u00edti el szelektivit\u00e1s\u00e1t \u00e9s perif\u00e9ri\u00e1s MAO-A-t is g\u00e1tol. Ezekn\u00e9l az adagokn\u00e1l a tiraminban gazdag \u00e9telek (\u00e9rlelt sajtok, p\u00e1colt h\u00fasok, l\u00f3bab, erjesztett sz\u00f3ja, csapolt s\u00f6r) hypertoni\u00e1s kr\u00edzist v\u00e1lthatnak ki. Maradjon a fel\u00edrt adagon, hogy elker\u00fclje ezt a kock\u00e1zatot.<\/div>\n

Gyakori mell\u00e9khat\u00e1sok<\/h2>\n

Headache (the most common — usually transient), arthralgia, dyspepsia, depression, postural hypotension, flu-like symptoms. Less common: hallucinations, insomnia (much less than selegiline), weight loss, falls. With levodopa: increased dyskinesia.<\/p>\n

\u26a0 Szerotonin szindr\u00f3ma \u2014 vesz\u00e9lyes k\u00f6lcs\u00f6nhat\u00e1sok<\/strong> MAO-B g\u00e1tl\u00f3 \u00e9s szerotonerg gy\u00f3gyszerek egy\u00fcttes alkalmaz\u00e1sa szerotonin szindr\u00f3ma<\/em>a k\u00f6vetkez\u0151ket okozhatja: izgatotts\u00e1g, izzad\u00e1s, remeg\u00e9s, hiperreflexia, l\u00e1z, hasmen\u00e9s, s\u00falyos esetben g\u00f6rcs\u00f6k \u00e9s hal\u00e1l. Ker\u00fclje:<\/strong> SSRI-k (fluoxetin, sertralin, paroxetin, citalopram, escitalopram), SNRI-k (venlafaxin, duloxetin), triciklikusok (amitriptilin, imipramin), petidin (meperidin), tramadol, dextrometorf\u00e1n, metadon, Szent J\u00e1nos kenyere, MDMA. Kiv\u00e1l\u00e1si id\u0151szakok:<\/strong> a fluoxetin abbahagy\u00e1sa 5 h\u00e9ttel a MAO-B g\u00e1tl\u00f3 kezd\u00e9se el\u0151tt; m\u00e1s SSRI\/SNRI abbahagy\u00e1sa legal\u00e1bb 2 h\u00e9ttel el\u0151tte; fluoxetin ne kezd\u0151dj\u00f6n 2 h\u00e9ten bel\u00fcl a MAO-B g\u00e1tl\u00f3 abbahagy\u00e1sa ut\u00e1n.<\/div>\n

Gy\u00f3gyszer-\u00e9tel k\u00f6lcs\u00f6nhat\u00e1sok<\/h2>\n