{"id":61710,"date":"2024-03-05T14:54:47","date_gmt":"2024-03-05T14:54:47","guid":{"rendered":"https:\/\/medsname.com\/dutas-t\/"},"modified":"2026-05-01T05:31:51","modified_gmt":"2026-05-01T05:31:51","slug":"dutas-t","status":"publish","type":"product","link":"https:\/\/medsbase.com\/hu\/product\/dutas-t\/","title":{"rendered":"Dutas T"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:18px 0;border-radius:4px;\">\n<p style=\"margin:0 0 8px 0;\"><strong>\ud83d\udca1 Gyors v\u00e1lasz<\/strong><\/p>\n<p style=\"margin:0;\"><strong>Dutas-T<\/strong> kombin\u00e1lja <strong>tamsulosin 0,4 mg<\/strong> (an alpha-blocker for immediate urinary symptom relief) with <strong>dutasteride 0.5 mg<\/strong> (a dual 5-alpha-reductase inhibitor that shrinks the prostate over 3\u20136 months). This dual-MOA single-capsule approach is preferred for men with moderate\u2013severe BPH, enlarged prostates (&gt;40 mL), or at risk of acute urinary retention. Once-daily dosing.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Mit kapsz a MedsBase-n\u00e1l:<\/strong> WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3 \u00b7 Diszkr\u00e9t csomagol\u00e1s \u00b7 Vil\u00e1gszerte sz\u00e1ll\u00edt\u00e1s \u00b7 1.400+ hiteles\u00edtett <a href=\"https:\/\/medsbase.com\/hu\/reviews\/\">v\u00e1s\u00e1rl\u00f3i v\u00e9lem\u00e9ny<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Minden rendel\u00e9st fedez a <a href=\"https:\/\/medsbase.com\/hu\/medsbase-re-shipment-assurance-policy\/\"><strong>\u00dajrak\u00fcld\u00e9si Garancia<\/strong><\/a> \u2014 ha a csomagod nem \u00e9rkezik meg 20 munkanapon bel\u00fcl, \u00fajrak\u00fcldj\u00fck.<\/p>\n<h3>Mi\u00e9rt rendelj a MedsBase-r\u00f3l<\/h3>\n<p>Generikus gy\u00f3gyszereink WHO-GMP min\u0151s\u00edt\u00e9s\u0171 gy\u00e1rt\u00f3kt\u00f3l sz\u00e1rmaznak, \u00e9s diszkr\u00e9t, egyszer\u0171 csomagol\u00e1sban sz\u00e1ll\u00edtjuk \u0151ket vil\u00e1gszerte \u2014 a csomagon nem szerepel a gy\u00f3gyszer neve. A k\u00e1rty\u00e1s fizet\u00e9sek egy szab\u00e1lyozott feldolgoz\u00f3n kereszt\u00fcl t\u00f6rt\u00e9nnek (a sz\u00e1mlale\u00edr\u00e1sok egy szab\u00e1lyozott k\u00e1rtyafizet\u00e9si feldolgoz\u00f3t tartalmaznak \u2014 soha nem \u201cMedsBase\u201d vagy b\u00e1rmilyen gy\u00f3gyszer neve). Kriptovalut\u00e1t \u00e9s SEPA banki \u00e1tutal\u00e1st is elfogadunk. Minden rendel\u00e9st a Reshipment Assurance Policy biztos\u00edt\u00e9k fedez.<\/p>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.95em;\">\n<strong>\ud83d\udd12 Mi\u00e9rt \u00e9rdemes a MedsBase-t\u0151l rendelni:<\/strong> Hiteles\u00edtett gy\u00e1rt\u00f3i forr\u00e1s \u00b7 Diszkr\u00e9t vil\u00e1gszerte sz\u00e1ll\u00edt\u00e1s \u00b7 Biztons\u00e1gos fizet\u00e9s (bankk\u00e1rtya, kriptovaluta) \u00b7 1 400+ \u00fcgyf\u00e9l \u00e1ltal 4,9\u2605-os \u00e9rt\u00e9kel\u00e9s\n<\/div>\n<h2><strong>What Is Dutas-T?<\/strong><\/h2>\n<p>Dutas-T is a fixed-dose combination capsule containing <strong>tamsulosin hydrochloride 0.4 mg + dutasteride 0.5 mg<\/strong>. The combination attacks BPH via two complementary mechanisms:<\/p>\n<ul>\n<li><strong>Tamsulosin (alpha-1A blocker):<\/strong> relaxes prostate and bladder-neck smooth muscle \u2014 rapid symptom relief within 1\u20132 weeks<\/li>\n<li><strong>Dutasteride (dual 5-ARI):<\/strong> blocks both type-1 and type-2 5-alpha-reductase enzymes, reducing DHT by ~90% and shrinking the prostate over 3\u20136 months<\/li>\n<\/ul>\n<p>The CombAT (Combination of Avodart and Tamsulosin) trial showed this combination reduced BPH progression, acute urinary retention, and surgery need more than either drug alone. Available strength: <strong>0.4 mg tamsulosin + 0.5 mg dutasteride<\/strong>. Manufactured by Dr. Reddy&#039;s Laboratories.<\/p>\n<h2><strong>Klinikai alkalmaz\u00e1s<\/strong><\/h2>\n<ul>\n<li><strong>Moderate\u2013severe BPH<\/strong> with enlarged prostate (&gt;30\u201340 mL) and moderate\u2013severe LUTS<\/li>\n<li><strong>Men at risk of acute urinary retention<\/strong> or needing BPH-related surgery<\/li>\n<li><strong>Men in whom tamsulosin alone has plateaued<\/strong> after 3\u20136 months and further progression prevention is desired<\/li>\n<\/ul>\n<h2><strong>Hogyan alkalmazand\u00f3<\/strong><\/h2>\n<ol>\n<li>Swallow the capsule whole with water \u2014 do not crush, chew, or open. The inner contents leak onto skin and this risks exposure to women of reproductive age (dutasteride is teratogenic via skin).<\/li>\n<li>Take once daily, roughly 30 minutes after the same meal each day (usually breakfast).<\/li>\n<li>Tamsulosin effect begins within days; the dutasteride effect builds over 3\u20136 months. Peak combination benefit at <strong>6\u201312 months<\/strong>.<\/li>\n<li>Do not skip doses \u2014 dutasteride has a 5-week half-life but tamsulosin effect is daily.<\/li>\n<li>Tell any ophthalmologist before cataract surgery (tamsulosin IFIS risk).<\/li>\n<li>Tell any clinician ordering PSA \u2014 dutasteride halves PSA readings.<\/li>\n<\/ol>\n<h2><strong>Mell\u00e9khat\u00e1sok<\/strong><\/h2>\n<p><strong>Tamsulosin-related:<\/strong> dizziness, headache, abnormal ejaculation, rhinitis, asthenia.<\/p>\n<p><strong>Dutasteride-related:<\/strong> decreased libido (~4%), erectile dysfunction (~4%), reduced ejaculate volume, gynecomastia, mood changes.<\/p>\n<p><strong>S\u00falyos (ritka):<\/strong> orthostatic hypotension, Intraoperative Floppy Iris Syndrome, priapism, persistent sexual side effects after discontinuation (PFS-equivalent).<\/p>\n<h2><strong>Who Should Not Take Dutas-T<\/strong><\/h2>\n<ul>\n<li><strong>Sz\u00fcl\u0151kor\u00fa n\u0151k<\/strong> \u2014 dutasteride is teratogenic. Do not handle broken capsules.<\/li>\n<li>Men with severe hepatic impairment (both components hepatically cleared)<\/li>\n<li>Orthostatic hypotension history<\/li>\n<li>Planned cataract \/ glaucoma surgery without telling ophthalmologist<\/li>\n<li>Strong CYP3A4 inhibitor co-therapy (ketoconazole, ritonavir)<\/li>\n<li>Known hypersensitivity to tamsulosin, dutasteride, finasteride, or sulphonamides<\/li>\n<\/ul>\n<h2><strong>Gy\u00f3gyszerk\u00f6lcs\u00f6nhat\u00e1sok<\/strong><\/h2>\n<ul>\n<li><strong>PDE5 g\u00e1tl\u00f3k<\/strong>: tamsulosin + sildenafil\/vardenafil = additive hypotension. Tadalafil 5 mg daily is often the pragmatic choice.<\/li>\n<li><strong>Er\u0151s CYP3A4 g\u00e1tl\u00f3k<\/strong>: raise both tamsulosin and dutasteride levels.<\/li>\n<li><strong>Egy\u00e9b alfa-blokkol\u00f3k<\/strong>: avoid \u2014 additive effect.<\/li>\n<li><strong>PSA-vizsg\u00e1lat<\/strong>: dutasteride halves PSA. Double the measured value for interpretation.<\/li>\n<\/ul>\n<h2><strong>Combination vs Monotherapy<\/strong><\/h2>\n<p>The CombAT trial (4-year outcomes) showed combination therapy reduced BPH clinical progression by ~66% vs dutasteride alone and ~41% vs tamsulosin alone. Combination is preferred when prostate is enlarged (&gt;30\u201340 mL) or PSA is elevated, suggesting ongoing glandular growth. For smaller prostates with pure symptom dominance, tamsulosin monotherapy is often sufficient.<\/p>\n<p>L\u00e1sd m\u00e9g: <a href=\"https:\/\/medsbase.com\/hu\/urimax-f\/\">Urimax-F<\/a> (tamsulosin + finasteride alternative) and our <a href=\"https:\/\/medsbase.com\/hu\/finasteride-vs-dutasteride\/\">Finasteride vs Dutasteride \u00fatmutat\u00f3<\/a>.<\/p>\n<h2><strong>T\u00e1rol\u00e1s<\/strong><\/h2>\n<p>Store at room temperature (15\u201330 \u00b0C \/ 59\u201386 \u00b0F), away from moisture and heat. Do not refrigerate. Keep in original blister. Keep away from women of reproductive age.<\/p>\n<h2 id=\"faqs\">Gyakran Ism\u00e9telt K\u00e9rd\u00e9sek<\/h2>\n<h3 class=\"wp-block-heading\">Why the combination pill?<\/h3>\n<p>Tamsulosin and dutasteride attack BPH by different mechanisms \u2014 smooth-muscle relaxation and DHT suppression. Combination therapy reduces BPH progression more than either drug alone (CombAT trial).<\/p>\n<h3 class=\"wp-block-heading\">How soon will symptoms improve?<\/h3>\n<p>Tamsulosin gives urinary symptom relief within 1\u20132 weeks. Dutasteride takes 3\u20136 months for prostate shrinkage. Full combination benefit is seen at 6\u201312 months.<\/p>\n<h3 class=\"wp-block-heading\">Is there a size below which combination is unnecessary?<\/h3>\n<p>For prostates under 30 mL without risk factors, tamsulosin monotherapy often suffices. Combination is strongest for prostates 30 mL and above or men with elevated PSA, bothersome symptoms, and BPH-progression risk factors.<\/p>\n<h3 class=\"wp-block-heading\">What about sexual side effects?<\/h3>\n<p>The dutasteride component contributes decreased libido (~4%) and erectile dysfunction (~4%) risk. The tamsulosin component contributes retrograde ejaculation. Discuss risk-benefit with a clinician, particularly if sexual function is a priority.<\/p>\n<h3 class=\"wp-block-heading\">Can I stop taking Dutas-T abruptly?<\/h3>\n<p>No \u2014 BPH is progressive and symptoms return over weeks to months. Dutasteride has a 5-week half-life, so its effect clears slowly; tamsulosin effect ends within days. For safe discontinuation, discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can I combine Dutas-T with a PDE5 inhibitor?<\/h3>\n<p>With care. Tamsulosin + sildenafil\/vardenafil = additive hypotension risk. Tadalafil 5 mg daily is often preferred \u2014 it also treats BPH symptoms on its own.<\/p>\n<h3 class=\"wp-block-heading\">Mi a helyzet a PSA-monitoroz\u00e1ssal?<\/h3>\n<p>Dutasteride halves PSA readings. Always tell your clinician you are on Dutas-T before any PSA test. Convention is to double the measured PSA for interpretation.<\/p>\n<h3 class=\"wp-block-heading\">Will Dutas-T prevent prostate cancer?<\/h3>\n<p>Not directly. The REDUCE trial suggested dutasteride reduced low-grade prostate cancer risk but slightly raised detection of high-grade tumours. Use dutasteride for BPH indications \u2014 not as prostate cancer prophylaxis.<\/p>\n<h3 class=\"wp-block-heading\">Kapcsol\u00f3d\u00f3 BPH term\u00e9kek<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/hu\/urimax\/\">Urimax (Tamszulosin 0,2 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/urimax-capsule\/\">Urimax kapszula (Tamszuloszin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/tamsuheal\/\">Tamsuheal (Tamszuloszin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/monolosin\/\">Monolosin (Tamszuloszin 0,4 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/urimax-f\/\">Urimax-F (Tamsulosin + Finasteride)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/nafodil\/\">Nafodil (Naftopidil 50 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/deetor\/\">Deetor (Dutasteride 0.5 mg)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:16px 0;border-radius:4px;font-size:0.9em;\">\n<p style=\"margin:0;\"><strong>\u2695\ufe0f Orvosi nyilatkozat:<\/strong> Ez az inform\u00e1ci\u00f3 t\u00e1j\u00e9koztat\u00f3 jelleg\u0171, \u00e9s nem helyettes\u00edti az orvosi tan\u00e1csot. Minden gy\u00f3gyszer szed\u00e9se, abbahagy\u00e1sa vagy m\u00f3dos\u00edt\u00e1sa el\u0151tt konzult\u00e1ljon klinikai szakemberrel. A v\u00e9nyk\u00f6teles term\u00e9keket csak orvosi fel\u00fcgyelet mellett haszn\u00e1lja.<\/p>\n<\/div>\n<p data-mb-link-target=\"minoxytop\" data-mb-anchor-variant=\"v2\" style=\"margin-top:1em;font-size:0.95em;color:#444;border-left:3px solid #2c7cb0;padding:0.5em 0.75em;background:#f4f8fb;\"><strong>L\u00e1sd m\u00e9g:<\/strong> <a href=\"https:\/\/medsbase.com\/hu\/minoxytop\/\"><strong>oral minoxidil (Minoxytop)<\/strong><\/a> \u2014 or\u00e1lis minoxidil a helyi kezel\u00e9sre nem reag\u00e1l\u00f3k sz\u00e1m\u00e1ra \u2014 Curatio Healthcare 1,25 \/ 2,5 \/ 5 mg tablett\u00e1k.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Kapcsol\u00f3d\u00f3 alternat\u00edv\u00e1k<\/h3>\n<p>Egy\u00e9b term\u00e9kek a <strong>F\u00e9rfi eg\u00e9szs\u00e9g<\/strong> v\u00e1s\u00e1rl\u00f3k \u00e1ltal szint\u00e9n megtekintett term\u00e9kek:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/hu\/poxet\/\">Poxet<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/zhewitra-oral-jelly\/\">Zhewitra Oral Jelly<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/vidalista-professional\/\">Vidalista Professional<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/filitra-professional\/\">Filitra Professional<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/hu\/p-force-fort\/\">P-Force Fort<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Jav\u00edtja a vizelet\u00fcr\u00edt\u00e9st<br \/>\n\u2705 Cs\u00f6kkenti a prosztata m\u00e9ret\u00e9t<br \/>\n\u2705 Enyh\u00edti a vizelet\u00fcr\u00edt\u00e9si panaszokat<br \/>\n\u2705 Kezeli a j\u00f3indulat\u00fa prosztatahyperplasi\u00e1t<br \/>\n\u2705 Enhances prostate health<\/p>\n<p>Dutas T contains Tamsulosin and Dutasteride.<\/p>","protected":false},"featured_media":61711,"comment_status":"closed","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3202,3141,3142],"product_tag":[5081,3474,3473],"class_list":{"0":"post-61710","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-benign-prostatic-hyperplasia-bph-treatment","7":"product_cat-category-overview","8":"product_cat-mens-health","9":"product_tag-dutas-t","10":"product_tag-dutasteride","11":"product_tag-tamsulosin","13":"first","14":"instock","15":"shipping-taxable","16":"purchasable","17":"product-type-variable","18":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product\/61710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/comments?post=61710"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/media\/61711"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/media?parent=61710"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product_brand?post=61710"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product_cat?post=61710"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/hu\/wp-json\/wp\/v2\/product_tag?post=61710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}