{"id":69013,"date":"2026-03-13T11:58:53","date_gmt":"2026-03-13T11:58:53","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&p=69013"},"modified":"2026-05-21T07:14:11","modified_gmt":"2026-05-21T07:14:11","slug":"kpv-lysine-proline-valine","status":"publish","type":"product","link":"https:\/\/medsbase.com\/hu\/product\/kpv-lysine-proline-valine\/","title":{"rendered":"KPV (Lizin-Prolin-Valin)"},"content":{"rendered":"

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Quick Answer \u2014 What is KPV?<\/h3>\n

KPV<\/strong> is the Lys-Pro-Val tripeptide \u2014 the C-terminal anti-inflammatory fragment of alpha-melanocyte stimulating hormone (\u03b1-MSH). Unlike broader melanocortin analogs, KPV has no pigmentation activity<\/strong>; its research signal is purely anti-inflammatory via NFkB inhibition and mast-cell stabilization. Studied for IBD, allergic inflammation, and skin-inflammation research. Supplied in 5\u00a0mg and 10\u00a0mg lyophilized vials for laboratory research use only.<\/p>\n<\/div>\n

Mit kapsz a MedsBase-n\u00e1l:<\/strong> Kutat\u00e1si min\u0151s\u00e9g\u0171 liofiliz\u00e1lt peptidok \u00b7 HPLC \u226599% tisztas\u00e1g (tan\u00fas\u00edtv\u00e1ny k\u00e9r\u00e9sre) \u00b7 Diszkr\u00e9t, h\u0151m\u00e9rs\u00e9klet-stabil csomagol\u00e1s \u00b7 Vil\u00e1gszerte peptid fut\u00e1rszolg\u00e1lat \u00b7 1,400+ hiteles\u00edtett v\u00e1s\u00e1rl\u00f3i v\u00e9lem\u00e9ny<\/a><\/div>\n

\ud83d\udce6 Minden rendel\u00e9st fedez a \u00dajrak\u00fcld\u00e9si Garancia<\/strong><\/a> \u2014 ha a csomagod nem \u00e9rkezik meg 20 munkanapon bel\u00fcl, \u00fajrak\u00fcldj\u00fck.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Specifik\u00e1ci\u00f3<\/th>\nR\u00e9szlet<\/th>\n<\/tr>\n<\/thead>\n
CAS sz\u00e1m<\/strong><\/td>\n67727-97-3<\/td>\n<\/tr>\n
Molekul\u00e1ris k\u00e9plet<\/strong><\/td>\nC16<\/sub>H30<\/sub>N4<\/sub>O4<\/sub><\/td>\n<\/tr>\n
Molekulat\u00f6meg<\/strong><\/td>\n342.43 Da<\/td>\n<\/tr>\n
Szekvencia<\/strong><\/td>\nLys-Pro-Val (\u03b1-MSH 11\u201313)<\/td>\n<\/tr>\n
Forma<\/strong><\/td>\nLiofiliz\u00e1lt por (vagy a sz\u00e1ll\u00edtott form\u00e1ban)<\/td>\n<\/tr>\n
Tisztas\u00e1g<\/strong><\/td>\n\u226599% (HPLC-vel ellen\u0151rizve, COA ig\u00e9ny szerint)<\/td>\n<\/tr>\n
T\u00e1rol\u00e1s<\/strong><\/td>\nLiofiliz\u00e1lt: 2\u20138 \u00b0C (h\u0171t\u0151szekr\u00e9ny) munkak\u00e9szletk\u00e9nt; \u221220 \u00b0C hossz\u00fa t\u00e1v\u00fa t\u00e1rol\u00e1sra lez\u00e1ratlan \u00fcvegek eset\u00e9n. Rekonstitu\u00e1lt: 2\u20138 \u00b0C, haszn\u00e1lat ~30 napon bel\u00fcl. V\u00e9dj\u00fck a f\u00e9nyt\u0151l. Ne fagyassza-v\u00e1lassza fel az \u00fajra\u00e1ll\u00edtott oldatot.<\/td>\n<\/tr>\n
Oldhat\u00f3s\u00e1g<\/strong><\/td>\nBakt\u00e9riumstatikus v\u00edz (aj\u00e1nlott) vagy steril v\u00edz r\u00f6videbb haszn\u00e1latra<\/td>\n<\/tr>\n
Kutat\u00e1si c\u00e9lra<\/strong><\/td>\nCsak laborat\u00f3riumi kutat\u00e1si c\u00e9lra. Nem haszn\u00e1lhat\u00f3 hum\u00e1n vagy \u00e1llatgy\u00f3gy\u00e1szati diagnosztikai vagy ter\u00e1pi\u00e1s c\u00e9lra.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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What Is KPV?<\/h2>\n

KPV<\/strong> is the three-letter one-letter-code shorthand for the Lys-Pro-Val tripeptide<\/strong> \u2014 the C-terminal three amino acids (positions 11\u201313) of alpha-melanocyte stimulating hormone (\u03b1-MSH). In the 1980s\u20131990s, multiple research groups noticed that the full \u03b1-MSH molecule produced two functionally separable effects: the well-known N-terminal MC-receptor pigmentation\/arousal activity, and a C-terminal gyullad\u00e1scs\u00f6kkent\u0151<\/strong> activity. When the C-terminal KPV tripeptide was synthesised and tested in isolation, it reproduced the anti-inflammatory effects without the pigmentation side-effects.<\/p>\n

Molecular weight approximately 342.4\u00a0Da. KPV is one of the smallest peptides in the melanocortin family and one of the most-studied anti-inflammatory research tripeptides. It is supplied as a high-purity lyophilized powder. KPV is laborat\u00f3riumi kutat\u00e1si c\u00e9lra szolg\u00e1l<\/strong> and is not intended for human or veterinary diagnosis or therapy. For mechanism, IBD research history, and stacking context, see our KPV research guide<\/a>.<\/p>\n

Mechanism of Action \u2014 Three Anti-Inflammatory Pathways<\/h2>\n

KPV’s anti-inflammatory activity operates through at least three complementary pathways, all of which converge on reducing inflammatory signaling without affecting other melanocortin functions:<\/p>\n