{"id":51987,"date":"2023-09-20T09:27:34","date_gmt":"2023-09-20T09:27:34","guid":{"rendered":"https:\/\/medsname.com\/vymada\/"},"modified":"2026-05-01T10:49:12","modified_gmt":"2026-05-01T10:49:12","slug":"vymada","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/vymada\/","title":{"rendered":"Vymada"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">\u26a1 \u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc \u2014 Vymada\u3068\u306f\uff1f<\/h3>\n<p style=\"margin:0;\"><strong>Vymada<\/strong> \u306f50mg\u3068100mg <strong>\u30b5\u30af\u30d3\u30c8\u30ea\u30eb\/\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3<\/strong> \u30ce\u30d0\u30eb\u30c6\u30a3\u30b9\u793e\u306e\u9320\u5264 \u2014 \u3053\u308c\u306f <strong>\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53-\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\uff08ARNI\uff09<\/strong>. \u30b5\u30af\u30d3\u30c8\u30ea\u30eb\u6210\u5206\u306f\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\uff08\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\u3001\u30d6\u30e9\u30b8\u30ad\u30cb\u30f3\u3001\u30a2\u30c9\u30ec\u30ce\u30e1\u30c7\u30e5\u30ea\u30f3\u3092\u5206\u89e3\u3059\u308b\u9175\u7d20\uff09\u3092\u963b\u5bb3\u3057\u3001\u6709\u76ca\u306a\u8840\u7ba1\u62e1\u5f35\u3068\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\u7d4c\u8def\u3092\u5897\u5f37\u3057\u307e\u3059\u3002\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3\u6210\u5206\u306f\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u53d7\u5bb9\u4f53\u3092\u906e\u65ad\u3057\u3001\u8840\u7ba1\u53ce\u7e2e\u3068\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u306b\u3088\u308b\u30ca\u30c8\u30ea\u30a6\u30e0\u8caf\u7559\u3092\u9632\u304e\u307e\u3059\u3002 <strong>HF-REF\uff08\u99c6\u51fa\u7387\u226440%\uff09\u306b\u5bfe\u3059\u308b\u7b2c\u4e00\u9078\u629e\u7642\u6cd5<\/strong> 2021 ESC\u304a\u3088\u30732022 AHA\/ACC\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u57fa\u3065\u304f \u2014 \u5b89\u5b9a\u3057\u305fHF-REF\u60a3\u8005\u306e\u591a\u304f\u3067ACE\u963b\u5bb3\u85ac\u307e\u305f\u306fARB\u3092\u4ee3\u66ff\u3057\u307e\u3059\uff08PARADIGM-HF 2014\u8a66\u9a13\u3067\u306f\u3001\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\u3068\u6bd4\u8f03\u3057\u3066\u5fc3\u8840\u7ba1\u6b7b\u307e\u305f\u306fHF\u5165\u9662\u304c20\uff05\u4f4e\u4e0b\uff09\u3002\u7528\u91cf\uff1a50mg\u3068100mg\u30921\u65e52\u56de\uff1b2\u301c4\u9031\u3054\u3068\u306b\u6f38\u5897\u3057\u3001\u76ee\u6a1997\/103mg\u30921\u65e52\u56de\u3002 <strong>\u598a\u5a20\u4e2d\u3001ACE\u963b\u5bb3\u85ac\u307e\u305f\u306fARB\u306b\u3088\u308b\u8840\u7ba1\u6d6e\u816b\u306e\u65e2\u5f80\u3001\u304a\u3088\u3073ACE\u963b\u5bb3\u85ac\u306e\u670d\u7528\u304b\u308936\u6642\u9593\u4ee5\u5185\u306f\u7d76\u5bfe\u7981\u5fcc\u3067\u3059\u3002<\/strong> \uff08\u8840\u7ba1\u6d6e\u816b\u3092\u907f\u3051\u308b\u305f\u3081\u306e\u30a6\u30a9\u30c3\u30b7\u30e5\u30a2\u30a6\u30c8\u671f\u9593\u304c\u5fc5\u8981\u3067\u3059\uff09\u3002<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>MedsBase\u3067\u5f97\u3089\u308c\u308b\u3082\u306e\uff1a<\/strong> WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143 \u00b7 \u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305 \u00b7 \u5168\u4e16\u754c\u914d\u9001 \u00b7 1,400\u4ef6\u4ee5\u4e0a\u306e\u78ba\u8a8d\u6e08\u307f <a href=\"https:\/\/medsbase.com\/ja\/reviews\/\">\u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u3001\u5f53\u5e97\u306e <a href=\"https:\/\/medsbase.com\/ja\/medsbase-re-shipment-assurance-policy\/\"><strong>\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u5546\u54c1\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u306f\u3001\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<h3>MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n<p>\u5f53\u5e97\u306e\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306f\u3001WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4ed5\u5165\u308c\u3001\u5168\u4e16\u754c\u3078\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u7121\u5730\u306e\u68b1\u5305\u3067\u767a\u9001\u3055\u308c\u307e\u3059\u3002\u914d\u9001\u7bb1\u306e\u5916\u5074\u306b\u306f\u533b\u85ac\u54c1\u540d\u306f\u4e00\u5207\u8a18\u8f09\u3055\u308c\u307e\u305b\u3093\u3002\u30ab\u30fc\u30c9\u6c7a\u6e08\u306f\u3001\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u3092\u7d4c\u7531\u3057\u3066\u51e6\u7406\u3055\u308c\uff08\u660e\u7d30\u66f8\u306e\u8868\u793a\u306b\u306f\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u306e\u307f\u304c\u8a18\u8f09\u3055\u308c\u3001\u300cMedsBase\u300d\u3084\u533b\u85ac\u54c1\u540d\u304c\u8868\u793a\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\uff09\u3001\u6697\u53f7\u8cc7\u7523\u3084SEPA\u9280\u884c\u632f\u8fbc\u3082\u3054\u5229\u7528\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306b\u306f\u3001\u5f53\u5e97\u306e\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc\u304c\u9069\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<h2 class=\"wp-block-heading\">Vymada\uff08\u30f4\u30a3\u30de\u30c0\uff09\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h2>\n<p>Vymada\u306f\u3001\u30ce\u30d0\u30eb\u30c6\u30a3\u30b9\u793e\u306e50mg\u3068100mg\u306e\u30b5\u30af\u30d3\u30c8\u30ea\u30eb\/\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3\u9320\u3067\u300128\u301c84\u9320\u3067\u4f9b\u7d66\u3055\u308c\u307e\u3059\u3002\u3082\u3068\u3082\u3068\u306fNovartis Entresto\uff082015\u5e74\uff09\u3068\u3057\u3066\u767a\u58f2\u3055\u308c\u305f\u3001\u6700\u521d\u306e\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53-\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\uff08ARNI\uff09\u30af\u30e9\u30b9\u3067\u3059\u3002<\/p>\n<h2 class=\"wp-block-heading\">ARNI\u306e\u4f5c\u7528\u6a5f\u5e8f<\/h2>\n<p>2\u3064\u306e\u88dc\u5b8c\u7684\u30e1\u30ab\u30cb\u30ba\u30e0\uff1a<\/p>\n<ul>\n<li><strong>\u30b5\u30af\u30d3\u30c8\u30ea\u30eb<\/strong> \uff08LBQ657\u306b\u5909\u63db\u3055\u308c\u308b\u30d7\u30ed\u30c9\u30e9\u30c3\u30b0\u304c\uff09\u963b\u5bb3\u3059\u308b <strong>neprilysin<\/strong>, \u3001\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u30da\u30d7\u30c1\u30c9\uff08ANP\u3001BNP\u3001CNP\uff09\u3001\u30d6\u30e9\u30b8\u30ad\u30cb\u30f3\u3001\u30a2\u30c9\u30ec\u30ce\u30e1\u30c7\u30e5\u30ea\u30f3\u3092\u5206\u89e3\u3059\u308b\u819c\u7d50\u5408\u578b\u30a8\u30f3\u30c9\u30da\u30d7\u30c1\u30c0\u30fc\u30bc\u3067\u3059\u3002\u963b\u5bb3\u306b\u3088\u308a\u3053\u308c\u3089\u306e\u6709\u76ca\u306a\u30da\u30d7\u30c1\u30c9\u306e\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u8840\u7ba1\u62e1\u5f35\u3001\u30ca\u30c8\u30ea\u30a6\u30e0\u5229\u5c3f\u3001\u6297\u7dda\u7dad\u5316\u4f5c\u7528\u3001\u304a\u3088\u3073\u4ea4\u611f\u795e\u7d4c\u7dca\u5f35\u306e\u4f4e\u4e0b\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3<\/strong> \u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II AT\u53d7\u5bb9\u4f53\u3092\u906e\u65ad<sub>1<\/sub> \u53d7\u5bb9\u4f53\u3092\u906e\u65ad\u3057\u3001\u8840\u7ba1\u53ce\u7e2e\u3068\u30a2\u30eb\u30c9\u30b9\u30c6\u30ed\u30f3\u306b\u3088\u308b\u30ca\u30c8\u30ea\u30a6\u30e0\u8caf\u7559\u3092\u9632\u304e\u307e\u3059\u3002<\/li>\n<li><strong>\u306a\u305c\u4f75\u7528\u3059\u308b\u306e\u3067\u3059\u304b\uff1f<\/strong> \u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u306f\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u3082\u5206\u89e3\u3057\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u306e\u307f\u3067\u306f\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3II\u304c\u4e0a\u6607\u3057\u307e\u3059\u3002ARB\u3068\u4f75\u7528\u3059\u308b\u3053\u3068\u3067\u305d\u306e\u554f\u984c\u3092\u9632\u304e\u307e\u3059\u3002\uff08\u4ee5\u524d\u306e\u5408\u5264\u3067\u3042\u308b\u30aa\u30de\u30d1\u30c8\u30ea\u30e9\u30c3\u30c8\u306f\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u3068ACE\u963b\u5bb3\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u304a\u308a\u3001\u8a31\u5bb9\u3067\u304d\u306a\u3044\u8840\u7ba1\u6d6e\u816b\u306e\u767a\u751f\u7387\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3057\u305f \u2014 \u305d\u306e\u305f\u3081ARNI\u306fACE\u963b\u5bb3\u85ac\u306e\u4ee3\u308f\u308a\u306bARB\u3092\u4f7f\u7528\u3057\u3001\u5207\u308a\u66ff\u3048\u524d\u306bACE\u963b\u5bb3\u85ac\u306e\u30a6\u30a9\u30c3\u30b7\u30e5\u30a2\u30a6\u30c8\u304c\u5fc5\u8981\u3067\u3059\u3002\uff09<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u30a8\u30d3\u30c7\u30f3\u30b9<\/h2>\n<p><strong>PARADIGM-HF (2014)<\/strong> \u2014 8,442\u4eba \u306eHF-REF\u60a3\u8005\uff08EF\u226640%\uff09\u304c\u65e2\u306b\u6700\u9069\u306a\u85ac\u7269\u7642\u6cd5\u3092\u53d7\u3051\u3066\u304a\u308a\u3001\u30b5\u30af\u30d3\u30c8\u30ea\u30eb\uff0f\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3\u307e\u305f\u306f\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb10mg 1\u65e52\u56de\u306b\u7121\u4f5c\u70ba\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u307e\u3057\u305f\u3002\u6709\u52b9\u6027\u306e\u305f\u3081\u65e9\u671f\u306b\u4e2d\u6b62\u3055\u308c\u307e\u3057\u305f\uff1a <strong>\u5fc3\u8840\u7ba1\u6b7b\u307e\u305f\u306f\u5fc3\u4e0d\u5168\u5165\u9662\u309220%\u6e1b\u5c11<\/strong> \uff08\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\uff09\u3001\u5168\u6b7b\u56e0\u6b7b\u4ea1\u306e16%\u6e1b\u5c11\u3002\u3053\u308c\u306fHF-REF\u306b\u304a\u3044\u3066\u30d5\u30eb\u30c9\u30fc\u30ba\u306eACE\u963b\u5bb3\u85ac\u3092\u76f4\u63a5\u6bd4\u8f03\u3067\u4e0a\u56de\u3063\u305f\u521d\u3081\u3066\u306e\u6cbb\u7642\u6cd5\u3067\u3057\u305f\u30022016\u5e74\u4ee5\u964d\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067ARNI\u3092HF-REF\u306e\u7b2c\u4e00\u9078\u629e\u6cbb\u7642\u3068\u3057\u3066\u78ba\u7acb\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><strong>PARAGON-HF (2019)<\/strong> \u2014 4,822\u4eba \u306eHF-PEF\u60a3\u8005\uff08EF\u226745%\uff09\uff1b\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\u9054\u6210\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u304c\uff0813%\u6e1b\u5c11\u3001p=0.06\uff09\u3001EF 45-57%\u306e\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u3067\u306f\u6709\u76ca\u6027\u304c\u307f\u3089\u308c\u307e\u3057\u305f\u3002FDA\u306f2021\u5e74\u306bHF-PEF\u3092\u542b\u3080\u3088\u308a\u5e83\u7bc4\u306aHF\u9069\u5fdc\u3092\u627f\u8a8d\u3057\u307e\u3057\u305f\u3002\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3067\u306f\u3001EF\u304c\u4e2d\u7b49\u5ea6\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u5834\u5408\u306eHF-PEF\u306b\u304a\u3051\u308bARNI\u3092\u3088\u308a\u614e\u91cd\u306b\u4f4d\u7f6e\u3065\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><strong>TRANSITION and PIONEER-HF (2019)<\/strong> \u2014 \u6025\u6027\u5fc3\u4e0d\u5168\u5165\u9662\u4e2d\u306bARNI\u3092\u958b\u59cb\u3059\u308b\u3053\u3068\u306f\u5b89\u5168\u3067\u3042\u308a\u3001\u5f8c\u3067\u5207\u308a\u66ff\u3048\u308b\u3088\u308a\u3082\u5927\u304d\u306aNT-proBNP\u306e\u4f4e\u4e0b\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/p>\n<h2 class=\"wp-block-heading\">\u9069\u5fdc\u75c7<\/h2>\n<ul>\n<li><strong>\u5de6\u5ba4\u99c6\u51fa\u7387\u304c\u4f4e\u4e0b\u3057\u305f\u5fc3\u4e0d\u5168\uff08HF-REF\u3001EF\u226640%\uff09<\/strong> \u2014 \u307b\u3068\u3093\u3069\u306e\u60a3\u8005\u3067ACE\u963b\u5bb3\u85ac\u307e\u305f\u306fARB\u306b\u4ee3\u308f\u308b\u7b2c\u4e00\u9078\u629e\u6cbb\u7642<\/li>\n<li><strong>\u5de6\u5ba4\u99c6\u51fa\u7387\u304c\u4fdd\u305f\u308c\u305f\u3001\u307e\u305f\u306f\u8efd\u5ea6\u4f4e\u4e0b\u3057\u305f\u5fc3\u4e0d\u5168<\/strong> \u2014 FDA\u627f\u8a8d\u3002EF\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u306b\u3088\u308a\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u4e0a\u306e\u4f4d\u7f6e\u4ed8\u3051\u306f\u7570\u306a\u308a\u307e\u3059\u3002<\/li>\n<li>\u6025\u6027\u5fc3\u4e0d\u5168\u5165\u9662\u4e2d\u306e\u6295\u4e0e\u958b\u59cb\uff08TRANSITION\u3001PIONEER-HF\uff09<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u7528\u91cf<\/h2>\n<p>\u898f\u683c\uff08\u30b5\u30af\u30d3\u30c8\u30ea\u30eb mg\uff0f\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3 mg\uff09\uff1a<\/p>\n<ul>\n<li>24\/26 mg\uff08\u4f4e\u7528\u91cf\uff09<\/li>\n<li>49\/51 mg\uff08\u4e2d\u7528\u91cf\uff09<\/li>\n<li>97\/103 mg\uff08\u76ee\u6a19\u7528\u91cf\uff09<\/li>\n<\/ul>\n<p><strong>\u6a19\u6e96\u7684\u306a\u6f38\u5897\uff1a<\/strong> ACE\u963b\u5bb3\u85ac\u307e\u305f\u306fARB\u3067\u5b89\u5b9a\u3057\u3066\u3044\u308b\u60a3\u8005\u3067\u306f49\/51 mg 1\u65e52\u56de\u304b\u3089\u3001ACE\u963b\u5bb3\u85ac\u672a\u4f7f\u7528\u3001\u4f4e\u8840\u5727\u3001\u814e\u6a5f\u80fd\u969c\u5bb3\u3001\u307e\u305f\u306f75\u6b73\u4ee5\u4e0a\u306e\u60a3\u8005\u3067\u306f24\/26 mg 1\u65e52\u56de\u304b\u3089\u958b\u59cb\u3057\u30012\uff5e4\u9031\u9593\u3054\u3068\u306b97\/103 mg 1\u65e52\u56de\u307e\u3067\u6f38\u5897\u3057\u307e\u3059\u3002<\/p>\n<p><strong>ACE\u963b\u5bb3\u85ac\u304b\u3089\u306e\u5207\u308a\u66ff\u3048\u306b\u95a2\u3059\u308b\u91cd\u8981\u306a\u30eb\u30fc\u30eb\uff1a<\/strong> <strong>36\u6642\u9593\u306e\u30a6\u30a9\u30c3\u30b7\u30e5\u30a2\u30a6\u30c8\u671f\u9593\u3092\u8a2d\u3051\u307e\u3059\u3002<\/strong> Vymada\u958b\u59cb\u524d\u306b\u6700\u5f8c\u306eACE\u963b\u5bb3\u85ac\u6295\u4e0e\u5f8c\u2014ACE\u963b\u5bb3\u85ac\u3068\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u306e\u4f75\u7528\u306f\u8840\u7ba1\u6d6e\u816b\u306e\u30ea\u30b9\u30af\u3092\u5927\u5e45\u306b\u9ad8\u3081\u307e\u3059\u3002ARB\u304b\u3089\u306e\u30a6\u30a9\u30c3\u30b7\u30e5\u30a2\u30a6\u30c8\u306f\u4e0d\u8981\u3067\u3059\u3002<\/p>\n<p><strong>\u7d4c\u904e\u89b3\u5bdf\uff1a<\/strong> \u8840\u5727\u3001\u30ab\u30ea\u30a6\u30e0\u3001\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u3092\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u30011\uff5e2\u9031\u9593\u5f8c\u3001\u304a\u3088\u30733\uff5e4\u304b\u6708\u3054\u3068\u306b\u78ba\u8a8d\u3057\u307e\u3059\u3002\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u306e\u8efd\u5ea6\u4e0a\u6607\u304c\u4e88\u60f3\u3055\u308c\u307e\u3059\uff08ACE\u963b\u5bb3\u85ac\uff0fARB\u3068\u540c\u69d8\uff09\u3002\u53cd\u5fdc\u306e\u8ffd\u8de1\u306b\u306fNT-proBNP\u3092\u4f7f\u7528\u3057\u307e\u3059\uff08\u6ce8\uff1aBNP\u306f\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u306b\u3088\u308a\u5206\u89e3\u3055\u308c\u308b\u305f\u3081\u4f7f\u7528\u3067\u304d\u307e\u305b\u3093\u3002\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u306e\u57fa\u8cea\u3067\u306a\u3044NT-proBNP\u3092\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\uff09\u3002<\/p>\n<h2 class=\"wp-block-heading\">\u526f\u4f5c\u7528<\/h2>\n<ul>\n<li><strong>\u4f4e\u8840\u5727<\/strong> \u2014 ACE\u963b\u5bb3\u85ac\uff0fARB\u5358\u72ec\u3088\u308a\u591a\u304f\u3001\u591a\u304f\u306e\u60a3\u8005\u3067\u7528\u91cf\u5236\u9650\u56e0\u5b50\u3068\u306a\u308b<\/li>\n<li><strong>\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7<\/strong> \u2014 \u30ab\u30ea\u30a6\u30e0\u5024\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/li>\n<li><strong>\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u4e0a\u6607<\/strong> \u2014 \u4e88\u60f3\u3055\u308c\u3001ACE\u963b\u5bb3\u85ac\/ARB\u3068\u540c\u69d8<\/li>\n<li><strong>\u8840\u7ba1\u6d6e\u816b<\/strong> \u2014 \u307e\u308c\uff08\u7d040.5%\uff09\uff1b\u9ed2\u4eba\u60a3\u8005\u3067\u9ad8\u7387<\/li>\n<li><strong>\u54b3<\/strong> \u2014 ACE\u963b\u5bb3\u85ac\u3088\u308a\u307e\u308c<\/li>\n<li>\u3081\u307e\u3044\u3001\u75b2\u52b4\u3001\u5931\u795e<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u7981\u5fcc<\/h2>\n<ul>\n<li>ACE\u963b\u5bb3\u85ac\u307e\u305f\u306fARB\u306b\u3088\u308b\u8840\u7ba1\u6d6e\u816b\u306e\u65e2\u5f80<\/li>\n<li>ACE\u963b\u5bb3\u85ac\u306e\u4f75\u7528\u3001\u307e\u305f\u306f\u6700\u5f8c\u306eACE\u963b\u5bb3\u85ac\u6295\u4e0e\u304b\u308936\u6642\u9593\u4ee5\u5185<\/li>\n<li>\u598a\u5a20\uff08\u50ac\u5947\u5f62\u6027\u2014\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3\u6210\u5206\uff09<\/li>\n<li>\u91cd\u5ea6\u809d\u969c\u5bb3\uff08Child-Pugh\u5206\u985eC\uff09<\/li>\n<li>\u904e\u654f\u75c7\u306e\u65e2\u5f80\u304c\u3042\u308b\u65b9<\/li>\n<li>\u7cd6\u5c3f\u75c5\u60a3\u8005\u306b\u304a\u3051\u308b\u30a2\u30ea\u30b9\u30ad\u30ec\u30f3\u4f75\u7528<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u85ac\u7269\u76f8\u4e92\u4f5c\u7528<\/h2>\n<ul>\n<li><strong>ACE\u963b\u5bb3\u85ac \u2014 \u91cd\u8981\u3002<\/strong> ARNI\u306b\u5207\u308a\u66ff\u3048\u308b\u524d\u306b36\u6642\u9593\u306e\u4f11\u85ac\u671f\u9593\u304c\u5fc5\u8981\u3067\u3059\u3002\u4f75\u7528\u306f\u7d76\u5bfe\u306b\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u30a2\u30ea\u30b9\u30ad\u30ec\u30f3<\/strong> \u2014 \u7cd6\u5c3f\u75c5\u3067\u306f\u7981\u5fcc\u306e\u7d44\u307f\u5408\u308f\u305b\u3067\u3059\u3002\u305d\u308c\u4ee5\u5916\u306e\u5834\u5408\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u30ab\u30ea\u30a6\u30e0\u88dc\u7d66\u5264\u3001\u30ab\u30ea\u30a6\u30e0\u4fdd\u6301\u6027\u5229\u5c3f\u85ac<\/strong> \u2014 \u76f8\u52a0\u7684\u306a\u9ad8\u30ab\u30ea\u30a6\u30e0\u8840\u75c7\u3002<\/li>\n<li><strong>NSAIDs<\/strong> \u2014 \u964d\u5727\u52b9\u679c\u3092\u6e1b\u5f31\u3055\u305b\u3001AKI\u30ea\u30b9\u30af\u3092\u4e0a\u6607\u3055\u305b\u307e\u3059\uff08\u5229\u5c3f\u85ac\u3068\u306e\u30c8\u30ea\u30d7\u30eb\u30ef\u30fc\u30df\u30fc\uff09\u3002<\/li>\n<li><strong>\u30ea\u30c1\u30a6\u30e0<\/strong> \u2014 \u814e\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u304c\u4f4e\u4e0b\u3059\u308b\u305f\u3081\u3001\u8840\u4e2d\u6fc3\u5ea6\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>PDE5\u963b\u5bb3\u85ac<\/strong> \u2014 \u76f8\u52a0\u7684\u306a\u4f4e\u8840\u5727\u30ea\u30b9\u30af\u3002<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u4fdd\u7ba1\u65b9\u6cd5<\/h2>\n<p>Vymada\u306f25\u2103\u4ee5\u4e0b\u3067\u3001\u5143\u306e\u30d6\u30ea\u30b9\u30bf\u30fc\u5305\u88c5\u306e\u307e\u307e\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u304a\u5b50\u69d8\u306e\u624b\u306e\u5c4a\u304b\u306a\u3044\u5834\u6240\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h2 id=\"faqs\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n<h3 class=\"wp-block-heading\">Vymada\u3092\u958b\u59cb\u3059\u308b\u524d\u306bACE\u963b\u5bb3\u85ac\u3092\u4e2d\u6b62\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u306f\u3044 \u2014 ACE\u963b\u5bb3\u85ac\u3092\u4e2d\u6b62\u3057\u3001Vymada\u3092\u958b\u59cb\u3059\u308b\u524d\u306b36\u6642\u9593\u304a\u5f85\u3061\u304f\u3060\u3055\u3044\u3002\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u3068ACE\u963b\u5bb3\u306e\u4f75\u7528\u306f\u3001\u8a31\u5bb9\u3067\u304d\u306a\u3044\u8840\u7ba1\u6d6e\u816b\u306e\u767a\u73fe\u7387\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\uff08\u30aa\u30de\u30d1\u30c8\u30ea\u30e9\u30c3\u30c8\u306e\u5931\u6557\u3057\u305fOVERTURE\u8a66\u9a13\u304b\u3089\u306e\u6559\u8a13\u3067\u3059\uff09\u3002ARB\u304b\u3089\u5207\u308a\u66ff\u3048\u308b\u5834\u5408\u3001\u4f11\u85ac\u671f\u9593\u306f\u4e0d\u8981\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">Vymada\u306f\u4ed6\u306e\u5fc3\u4e0d\u5168\u6cbb\u7642\u85ac\u306e\u4ee3\u308f\u308a\u306b\u306a\u308a\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u3044\u3044\u3048\u3002Vymada\u306f\u5fc3\u4e0d\u5168\u6cbb\u7642\u306b\u304a\u3051\u308bACE\u963b\u5bb3\u85ac\u307e\u305f\u306fARB\u306e\u5f79\u5272\u3092\u4ee3\u66ff\u3057\u307e\u3059\u3002\u30d9\u30fc\u30bf\u906e\u65ad\u85ac\u3001\u30df\u30cd\u30e9\u30eb\u30b3\u30eb\u30c1\u30b3\u30a4\u30c9\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\uff08\u30b9\u30d4\u30ed\u30ce\u30e9\u30af\u30c8\u30f3\u3001\u30a8\u30d7\u30ec\u30ec\u30ce\u30f3\uff09\u3001SGLT2\u963b\u5bb3\u85ac\u3001\u304a\u3088\u3073\u5229\u5c3f\u85ac\u306f\u305d\u306e\u307e\u307e\u7d99\u7d9a\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u73fe\u4ee3\u306eHFrEF\u306b\u304a\u3051\u308b\u300c\u56db\u5264\u4f75\u7528\u7642\u6cd5\u300d\u306f\u3001ARNI + \u30d9\u30fc\u30bf\u906e\u65ad\u85ac + MR\u62ee\u6297\u85ac + SGLT2\u963b\u5bb3\u85ac\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u306a\u305cBNP\u3067\u306f\u306a\u304fNT-proBNP\u304c\u6e2c\u5b9a\u3055\u308c\u308b\u306e\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\uff08Vymada\u304c\u963b\u5bb3\u3059\u308b\u9175\u7d20\uff09\u306fBNP\u3092\u5206\u89e3\u3057\u307e\u3059\u304c\u3001NT-proBNP\u306f\u5206\u89e3\u3057\u307e\u305b\u3093\u3002ARNI\u7642\u6cd5\u4e2d\u306f\u3001BNP\u306e\u5206\u89e3\u304c\u6291\u5236\u3055\u308c\u308b\u305f\u3081BNP\u5024\u304c\u4eba\u70ba\u7684\u306b\u4e0a\u6607\u3057\u3001\u6e2c\u5b9a\u5024\u306e\u89e3\u91c8\u304c\u56f0\u96e3\u306b\u306a\u308a\u307e\u3059\u3002NT-proBNP\u306f\u5207\u65ad\u7523\u7269\u3067\u3042\u308a\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u306e\u57fa\u8cea\u3067\u306f\u306a\u3044\u305f\u3081\u3001ARNI\u7642\u6cd5\u4e2d\u3082\u5fc3\u4e0d\u5168\u306e\u91cd\u75c7\u5ea6\u3092\u53cd\u6620\u3057\u7d9a\u3051\u307e\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u598a\u5a20\u4e2d\u306bVymada\u3092\u670d\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u3044\u3044\u3048\u3001\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3\u6210\u5206\u306b\u306f\u50ac\u5947\u5f62\u6027\u304c\u3042\u308a\u307e\u3059\uff08\u80ce\u5150\u814e\u7121\u767a\u751f\u3001\u7f8a\u6c34\u904e\u5c11\uff09\u3002\u8a08\u753b\u598a\u5a20\u524d\u3001\u307e\u305f\u306f\u4e88\u671f\u305b\u306c\u598a\u5a20\u304c\u78ba\u8a8d\u3055\u308c\u305f\u6642\u70b9\u3067ARNI\u3092\u4e2d\u6b62\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3 class=\"wp-block-heading\">Vymada\u3092\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u3069\u3053\u3067\u8cfc\u5165\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n<p>Vymada\uff08\u30b5\u30af\u30d3\u30c8\u30ea\u30eb\uff0f\u30d0\u30eb\u30b5\u30eb\u30bf\u30f3 50mg\u304a\u3088\u3073100mg\u300128\u301c84\u9320\uff09\u306f\u3001MedsBase\u306b\u3066\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305\u3068\u5168\u4e16\u754c\u914d\u9001\u3067\u3054\u8cfc\u5165\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2 class=\"wp-block-heading\">\u95a2\u9023\u3059\u308b\u5fc3\u8840\u7ba1\u6cbb\u7642\u85ac<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ja\/abana\/\">Abana \u2014 \u30a2\u30fc\u30e6\u30eb\u30f4\u30a7\u30fc\u30c0\u306e\u5fc3\u81d3\u7528\u88fd\u5264<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/ambrican\/\">Ambrican \u2014 \u30a2\u30f3\u30d6\u30ea\u30bb\u30f3\u30bf\u30f35mg\uff08ERA\uff1aPAH\u6cbb\u7642\u85ac\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/cardace\/\">Cardace \u2014 \u30e9\u30df\u30d7\u30ea\u30eb\uff08ACE\u963b\u5bb3\u85ac\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/cordarone\/\">Cordarone \u2014 \u30a2\u30df\u30aa\u30c0\u30ed\u30f3 100\/200 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/lonitab\/\">Lonitab \u2014 \u30df\u30ce\u30ad\u30b7\u30b8\u30eb5mg\uff08\u7d4c\u53e3\u8840\u7ba1\u62e1\u5f35\u85ac\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/xarelto-20\/\">Xarelto 20 \u2014 \u30ea\u30d0\u30fc\u30ed\u30ad\u30b5\u30d0\u30f320mg\uff08DOAC\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/high-blood-pressure-medication\/\"><strong>\u3059\u3079\u3066\u306e\u9ad8\u8840\u5727\u6cbb\u7642\u85ac\u3092\u898b\u308b<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 \u533b\u7642\u4e0a\u306e\u514d\u8cac\u4e8b\u9805.<\/strong> \u3053\u306e\u30da\u30fc\u30b8\u306f\u60c5\u5831\u63d0\u4f9b\u306e\u307f\u3092\u76ee\u7684\u3068\u3057\u3066\u304a\u308a\u3001\u8cc7\u683c\u3092\u6301\u3064\u533b\u7642\u5c02\u9580\u5bb6\u306b\u3088\u308b\u533b\u5b66\u7684\u30a2\u30c9\u30d0\u30a4\u30b9\u306b\u4ee3\u308f\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u9ad8\u8840\u5727\u3001\u5fc3\u4e0d\u5168\u3001\u4e0d\u6574\u8108\u306f\u3001\u533b\u5e2b\u306b\u3088\u308b\u8a3a\u65ad\u3001\u7d4c\u904e\u89b3\u5bdf\u3001\u7528\u91cf\u306e\u500b\u5225\u8abf\u6574\u304c\u5fc5\u8981\u3067\u3059\u3002\u30d9\u30fc\u30bf\u906e\u65ad\u85ac\u306f\u5fc5\u305a\u533b\u5e2b\u306e\u6307\u5c0e\u306e\u3082\u3068\u3067\u3054\u4f7f\u7528\u304f\u3060\u3055\u3044\u3002<\/div>","protected":false},"excerpt":{"rendered":"<p>Vymada\u306f\u3001\u30ce\u30d0\u30eb\u30c6\u30a3\u30b9\u793e\u306e\u30b5\u30af\u30d3\u30c8\u30ea\u30eb\uff0f\u30d0\u30eb\u30b5\u30eb\u30bf\u30f350\uff0f100mg\u9320\u3067\u3042\u308a\u3001\u4e16\u754c\u521d\u306e\u30a2\u30f3\u30b8\u30aa\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f53\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\u963b\u5bb3\u85ac\uff08ARNI\uff09\u3067\u3001\u5168\u4e16\u754c\u3067Entresto\u3068\u3057\u3066\u8ca9\u58f2\u3055\u308c\u3066\u3044\u307e\u3059\u3002PARADIGM-HF\u8a66\u9a13\uff082014\u5e74\uff09\u3067\u306f\u3001HFrEF\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u30a8\u30ca\u30e9\u30d7\u30ea\u30eb\u3068\u6bd4\u8f03\u3057\u3066\u5fc3\u8840\u7ba1\u6b7b\u307e\u305f\u306f\u5fc3\u4e0d\u5168\u5165\u9662\u306e\u8907\u5408\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u309220\uff05\u6e1b\u5c11\u3055\u305b\u308b\u3053\u3068\u304c\u78ba\u7acb\u3055\u308c\u307e\u3057\u305f\u30022021\u5e74ESC\u304a\u3088\u30732022\u5e74AHA\uff0fACC\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u57fa\u3065\u304d\u3001\u5b89\u5b9a\u3057\u305fHFrEF\u60a3\u8005\u306b\u304a\u3051\u308bACE\u963b\u5bb3\u85ac\uff0fARB\u306b\u4ee3\u308f\u308b\u7b2c\u4e00\u9078\u629e\u85ac\u3068\u3057\u3066\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u91cd\u8981\uff1aACE\u963b\u5bb3\u85ac\u304b\u3089\u306e\u5207\u308a\u66ff\u3048\u306b\u306f\u300136\u6642\u9593\u306e\u4f11\u85ac\u671f\u9593\u304c\u5fc5\u8981\u3067\u3059\uff08\u8840\u7ba1\u6027\u6d6e\u816b\u306e\u30ea\u30b9\u30af\uff09\u3002BNP\u3067\u306f\u6cbb\u7642\u52b9\u679c\u3092\u8ffd\u8de1\u3067\u304d\u306a\u3044\u305f\u3081\u3001NT-proBNP\u3092\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>","protected":false},"featured_media":51988,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260,3356],"product_tag":[3437,3438,3439],"class_list":{"0":"post-51987","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_cat-high-blood-pressure-medication","10":"product_tag-sacubitril","11":"product_tag-valsartan","12":"product_tag-vymada","14":"first","15":"outofstock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product\/51987","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/comments?post=51987"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/media\/51988"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/media?parent=51987"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_brand?post=51987"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_cat?post=51987"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_tag?post=51987"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}