{"id":53353,"date":"2023-09-20T09:45:18","date_gmt":"2023-09-20T09:45:18","guid":{"rendered":"https:\/\/medsname.com\/keytruda\/"},"modified":"2026-04-30T10:25:12","modified_gmt":"2026-04-30T10:25:12","slug":"keytruda","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/keytruda\/","title":{"rendered":"Keytruda"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">\u26a1 \u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc \u2014 Keytruda\u3068\u306f\uff1f<\/h3>\n<p style=\"margin:0;\"><strong>Keytruda<\/strong> \u306f\u3001 <strong>\u70b9\u6ef4\u9759\u6ce8<\/strong> \u30e1\u30eb\u30af\uff08MSD\uff09\u306e\u3001\uff5e\u3092\u542b\u3080 <strong>\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6 100 mg\uff0f4 mL<\/strong> \u2014 \u30d2\u30c8\u5316\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3067\u3001 <strong>PD-1\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264<\/strong>. \u3002\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u3001\u514d\u75ab\u7cfb\u306e\u304c\u3093\u7d30\u80de\u8a8d\u8b58\u3092\u963b\u5bb3\u3059\u308b\u4f5c\u7528\u3092\u89e3\u9664\u3057\u307e\u3059\u3002\u627f\u8a8d\u3055\u308c\u3066\u3044\u308b <strong>\u591a\u304f\u306e\u304c\u3093\u7a2e<\/strong>\uff1a\u9032\u884c\u6027\u9ed2\u8272\u816b\u3001\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\uff08NSCLC\uff09\u3001\u982d\u9838\u90e8\u6241\u5e73\u4e0a\u76ae\u304c\u3093\u3001\u53e4\u5178\u7684\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u3001\u5c3f\u8def\u4e0a\u76ae\u304c\u3093\u3001MSI-H\uff0fdMMR\u967d\u6027\u56fa\u5f62\u304c\u3093\uff08\u816b\u760d\u30bf\u30a4\u30d7\u3092\u554f\u308f\u305a\uff09\u3001\u80c3\u304c\u3093\u3001\u98df\u9053\u304c\u3093\u3001\u5b50\u5bae\u9838\u304c\u3093\u3001\u809d\u7d30\u80de\u304c\u3093\u3001\u814e\u7d30\u80de\u304c\u3093\u3001\u5b50\u5bae\u4f53\u304c\u3093\u3001\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u3001\u306a\u3069\u591a\u6570\u3002 <strong>\u6a19\u6e96\u7684\u306a\u6210\u4eba\u7528\u91cf\uff1a<\/strong> \u307e\u305f\u306f <strong>400 mg\u30926\u9031\u9593\u3054\u3068\u306b\u9759\u8108\u5185\u6295\u4e0e<\/strong>, \u300130\u5206\u304b\u3051\u3066\u70b9\u6ef4\u9759\u6ce8\u3057\u307e\u3059\u3002 <strong>\u672c\u5264\u306f\u75c5\u9662\u307e\u305f\u306f\u816b\u760d\u79d1\u30c7\u30a4\u30e6\u30cb\u30c3\u30c8\u306e\u70b9\u6ef4\u30bb\u30f3\u30bf\u30fc\u3067\u306e\u307f\u3001\u8a13\u7df4\u3092\u53d7\u3051\u305f\u533b\u7642\u30b9\u30bf\u30c3\u30d5\u306b\u3088\u3063\u3066\u6295\u4e0e\u3055\u308c\u307e\u3059 \u2014 \u81ea\u5df1\u6295\u4e0e\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/strong> \u4e3b\u306a\u30ea\u30b9\u30af\uff1a <strong>\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAE\uff09<\/strong> \u2014 \u3042\u3089\u3086\u308b\u81d3\u5668\u7cfb\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\uff08\u80ba\u81d3\u708e\u3001\u5927\u8178\u708e\u3001\u809d\u708e\u3001\u5185\u5206\u6ccc\u969c\u5bb3\u3001\u76ae\u819a\u53cd\u5fdc\u3001\u814e\u708e\u3001\u795e\u7d4c\u969c\u5bb3\uff09\u3001\u5168\u8eab\u6027\u526f\u814e\u76ae\u8cea\u30db\u30eb\u30e2\u30f3\u5264\u306e\u6295\u4e0e\u3084\u6c38\u4e45\u7684\u306a\u6295\u4e0e\u4e2d\u6b62\u304c\u5fc5\u8981\u306b\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>MedsBase\u3067\u5f97\u3089\u308c\u308b\u3082\u306e\uff1a<\/strong> WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143 \u00b7 \u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305 \u00b7 \u5168\u4e16\u754c\u914d\u9001 \u00b7 1,400\u4ef6\u4ee5\u4e0a\u306e\u78ba\u8a8d\u6e08\u307f <a href=\"https:\/\/medsbase.com\/ja\/reviews\/\">\u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u3001\u5f53\u5e97\u306e <a href=\"https:\/\/medsbase.com\/ja\/medsbase-re-shipment-assurance-policy\/\"><strong>\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u5546\u54c1\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u306f\u3001\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;\"><strong>\u26a0 \u5c02\u9580\u533b\u306e\u76e3\u7763\u304c\u5fc5\u8981\u3067\u3059\u3002<\/strong> \u6297\u304c\u3093\u5264\u306f\u3001\u78ba\u5b9a\u8a3a\u65ad\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u75c5\u671f\u5206\u985e\u3001\u304a\u3088\u3073\u660e\u78ba\u306a\u6cbb\u7642\u8a08\u753b\u306b\u57fa\u3065\u3044\u3066\u3001\u62c5\u5f53\u306e\u816b\u760d\u533b\u304c\u51e6\u65b9\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u816b\u760d\u533b\u4e3b\u5c0e\u306e\u6cbb\u7642\u8a08\u753b\u5916\u3067\u3001\u6297\u304c\u3093\u5264\u306e\u958b\u59cb\u3001\u4e2d\u6b62\u3001\u7528\u91cf\u5909\u66f4\u3001\u4f7f\u7528\u3092\u884c\u308f\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u307b\u3068\u3093\u3069\u306e\u6297\u304c\u3093\u5264\u306f\u3001\u5b9a\u671f\u7684\u306a\u8840\u6db2\u691c\u67fb\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\uff08FBC\u3001LFT\u3001\u814e\u6a5f\u80fd\uff09\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u598a\u5a20\u4e2d\u306f\u7d76\u5bfe\u7981\u5fcc\u3067\u3042\u308a\u3001\u91cd\u5927\u306a\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002<\/div>\n<div style=\"background:#f4f8fb;border:1px solid #d6e4ec;padding:12px 18px;margin:14px 0;border-radius:4px;font-size:14px;color:#3a5160;text-align:center;\">\n<strong>\ud83d\udd12 \u6697\u53f7\u5316\u3055\u308c\u305f\u30c1\u30a7\u30c3\u30af\u30a2\u30a6\u30c8<\/strong> \u00b7 <strong>\ud83d\udcb3 \u8a8d\u8a3c\u6e08\u307f\u30d7\u30ed\u30bb\u30c3\u30b5\u30fc<\/strong> \u00b7 <strong>\ud83d\ude9a \u5168\u4e16\u754c\u914d\u9001<\/strong> \u00b7 <strong>\u2b50 4.9\/5\uff081,400\u540d\u4ee5\u4e0a\u306e\u304a\u5ba2\u69d8\uff09<\/strong>\n<\/div>\n<h2 class=\"wp-block-heading\">Keytruda\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h2>\n<p>Keytruda\uff08<strong>\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6<\/strong>)\u306f\u30e1\u30eb\u30af\uff08MSD\uff09\u306e\u30d2\u30c8\u5316IgG4\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3067\u3001\u6a19\u7684\u3068\u3059\u308b <strong>\u30d7\u30ed\u30b0\u30e9\u30e0\u7d30\u80de\u6b7b\u30bf\u30f3\u30d1\u30af\u8cea1\uff08PD-1\uff09<\/strong> T\u7d30\u80de\u4e0a\u306e\u53d7\u5bb9\u4f53\u3002PD-1\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u3001\u304c\u3093\u7d30\u80de\u304c\u514d\u75ab\u56de\u907f\u306b\u5229\u7528\u3059\u308b\u514d\u75ab\u30d6\u30ec\u30fc\u30ad\u3092\u89e3\u9664\u3057\u307e\u3059\u30022014\u5e74\u306bFDA\u627f\u8a8d\u3092\u53d6\u5f97\u3057\u305fKeytruda\u306f\u3001\u73fe\u5728\u3001\u4ed6\u306e\u3069\u306e\u514d\u75ab\u7642\u6cd5\u3088\u308a\u3082\u591a\u304f\u306e\u304c\u3093\u7a2e\u306b\u9069\u5fdc\u304c\u8a8d\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u9032\u884c\u671f\u9ed2\u8272\u816b\u3084\u9032\u884c\u671f\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\uff08NSCLC\uff09\u3001\u305d\u306e\u4ed6\u591a\u304f\u306e\u304c\u3093\u7a2e\u306b\u304a\u3051\u308b\u6cbb\u7642\u3092\u5909\u9769\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u3001\u6b21\u306e\u5264\u5f62\u3067 <strong>\u70b9\u6ef4\u9759\u6ce8\u7528\u6fc3\u7e2e\u6db2\uff08100 mg\/4 mL\u30d0\u30a4\u30a2\u30eb\uff09<\/strong> \u3092\u751f\u7406\u98df\u5869\u6db2\u307e\u305f\u306f5%\u30d6\u30c9\u30a6\u7cd6\u6db2\u3067\u5e0c\u91c8\u3057\u3001\u75c5\u9662\u307e\u305f\u306f\u816b\u760d\u5185\u79d1\u30c7\u30a4\u30e6\u30cb\u30c3\u30c8\u306b\u306630\u5206\u304b\u3051\u3066\u7de9\u5f90\u306b\u70b9\u6ef4\u9759\u6ce8\u3057\u307e\u3059\u3002\u672c\u5264\u306f <strong>\u3057\u307e\u305b\u3093<\/strong> \u7d4c\u53e3\u5264\u3068\u3057\u3066\u306e\u5165\u624b\u306f\u3067\u304d\u305a\u3001\u81ea\u5df1\u6295\u4e0e\u306f\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<h2 class=\"wp-block-heading\">Keytruda\u306f\u3069\u306e\u3088\u3046\u306b\u4f5c\u7528\u3057\u307e\u3059\u304b\uff1f<\/h2>\n<p>\u304c\u3093\u7d30\u80de\u306f\u3057\u3070\u3057\u3070\u3001 <strong>PD-L1<\/strong> \u30ea\u30ac\u30f3\u30c9\u3092\u8868\u9762\u306b\u767a\u73fe\u3057\u3066\u3044\u307e\u3059\u3002PD-L1\u304c <strong>PD-1<\/strong> \u816b\u760d\u6d78\u6f64T\u7d30\u80de\u4e0a\u306e\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3059\u308b\u3068\u3001T\u7d30\u80de\u306b\u505c\u6b62\u547d\u4ee4\u3092\u51fa\u3057\u3001\u5b9f\u8cea\u7684\u306b\u6297\u816b\u760d\u514d\u75ab\u5fdc\u7b54\u3092\u30aa\u30d5\u306b\u3057\u307e\u3059\u3002\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u3001\u3053\u306ePD-1\uff0fPD-L1\u76f8\u4e92\u4f5c\u7528\u3092\u963b\u5bb3\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\uff1a<\/p>\n<ul>\n<li><strong>\u514d\u75ab\u30d6\u30ec\u30fc\u30ad\u3092\u89e3\u9664\u3057\u307e\u3059<\/strong> \u2014 PD-1\u306e\u963b\u5bb3\u306b\u3088\u308a\u3001\u816b\u760d\u7279\u7570\u7684T\u7d30\u80de\u306f\u304c\u3093\u7d30\u80de\u3092\u8a8d\u8b58\u3057\u3066\u7834\u58ca\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u816b\u760d\u306ePD-L1\u767a\u73fe\u306f\u6cbb\u7642\u53cd\u5fdc\u6027\u3092\u4e88\u6e2c\u3059\u308b\u3053\u3068\u304c\u591a\u3044<\/strong> \u2014 PD-L1\u67d3\u8272\u5f37\u5ea6\u304c\u9ad8\u3044\u816b\u760d\uff08TPS 50%\u4ee5\u4e0a\uff09\u306f\u3001PD-L1\u9670\u6027\u816b\u760d\u3088\u308a\u3082\u9ad8\u3044\u594f\u52b9\u7387\u3092\u793a\u3057\u3001\u7279\u306b\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\uff08NSCLC\uff09\u3067\u9855\u8457\u3067\u3059\u3002\u4e00\u90e8\u306e\u9069\u5fdc\u75c7\u3067\u306f\u3001\u6cbb\u7642\u524d\u306bPD-L1\u691c\u67fb\u304c\u5fc5\u8981\u3068\u306a\u308a\u307e\u3059\u3002<\/li>\n<li><strong>MSI-H \/ dMMR\u304c\u3093\u306fPD-L1\u767a\u73fe\u306b\u95a2\u4fc2\u306a\u304f\u594f\u52b9\u3059\u308b<\/strong> \u2014 \u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u6b20\u640d\u307e\u305f\u306f\u30de\u30a4\u30af\u30ed\u30b5\u30c6\u30e9\u30a4\u30c8\u4e0d\u5b89\u5b9a\u6027\u3092\u6709\u3059\u308b\u816b\u760d\u306f\u3001PD-L1\u306e\u767a\u73fe\u72b6\u614b\u306b\u304b\u304b\u308f\u3089\u305a\u3001\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u85ac\u306b\u9ad8\u3044\u611f\u53d7\u6027\u3092\u793a\u3057\u307e\u3059\u3002Keytruda\u306f\u3001MSI-H\/dMMR\u304c\u3093\u306b\u5bfe\u3057\u3066\u816b\u760d\u7a2e\u6a2a\u65ad\u7684\u306a\u9069\u5fdc\u3092\u53d6\u5f97\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n<li><strong>\u816b\u760d\u907a\u4f1d\u5b50\u5909\u7570\u91cf\uff08TMB\uff09<\/strong> \u2014 TMB\u304c\u9ad8\u3044\u816b\u760d\u306f\u3001\u514d\u75ab\u7cfb\u304c\u8a8d\u8b58\u3059\u308b\u30cd\u30aa\u30a2\u30f3\u30c1\u30b2\u30f3\u3092\u3088\u308a\u591a\u304f\u751f\u6210\u3057\u307e\u3059\u3002\u4e00\u90e8\u306eKeytruda\u306e\u9069\u5fdc\u75c7\u3067\u306f\u3001TMB 10 mut\/Mb\u4ee5\u4e0a\u304c\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3068\u3057\u3066\u7528\u3044\u3089\u308c\u307e\u3059\u3002<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u4f7f\u7528\u76ee\u7684\u3068\u9069\u5fdc\u75c7<\/h2>\n<p>Keytruda\u306f\u3001\u4e3b\u8981\u306a\u898f\u5236\u5f53\u5c40\uff08FDA\u3001EMA\u3001MHRA\u306a\u3069\uff09\u306b\u3088\u308a\u3001\u6975\u3081\u3066\u5e83\u7bc4\u306a\u304c\u3093\u7a2e\u3067\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e3b\u306a\u6210\u4eba\u306e\u9069\u5fdc\u75c7\u306f\u4ee5\u4e0b\u306e\u901a\u308a\u3067\u3059\u3002<\/p>\n<ul>\n<li><strong>\u60aa\u6027\u9ed2\u8272\u816b<\/strong> \u2014 \u5207\u9664\u4e0d\u80fd\u306a\u9032\u884c\u30fb\u8ee2\u79fb\u6027\u60aa\u6027\u9ed2\u8272\u816b\u3001\u5b8c\u5168\u5207\u9664\u5f8c\u306e\u30b9\u30c6\u30fc\u30b8IIB\/IIC\/III\u306b\u5bfe\u3059\u308b\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5<\/li>\n<li><strong>\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\uff08NSCLC\uff09<\/strong> \u2014 PD-L1 TPS 50%\u4ee5\u4e0a\u306e\u8ee2\u79fb\u6027NSCLC\u306b\u5bfe\u3059\u308b\u4e00\u6b21\u5358\u72ec\u7642\u6cd5\u3001PD-L1\u767a\u73fe\u91cf\u306b\u95a2\u308f\u3089\u306a\u3044\u4e00\u6b21\u5316\u5b66\u7642\u6cd5\u3068\u306e\u4f75\u7528\u3001PD-L1 1%\u4ee5\u4e0a\u306b\u5bfe\u3059\u308b\u4e8c\u6b21\u5358\u72ec\u7642\u6cd5\u3001\u5207\u9664\u5f8c\u306e\u8853\u5f8c\u88dc\u52a9\u7642\u6cd5<\/li>\n<li><strong>\u982d\u9838\u90e8\u6241\u5e73\u4e0a\u76ae\u304c\u3093\uff08HNSCC\uff09<\/strong> \u2014 \u4e00\u6b21\u6cbb\u7642\u306e\u8ee2\u79fb\u30fb\u518d\u767a\u4f8b\uff08\u5316\u5b66\u7642\u6cd5\u306e\u6709\u7121\u3092\u554f\u308f\u306a\u3044\uff09<\/li>\n<li><strong>\u53e4\u5178\u7684\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b<\/strong> \u2014 \u591a\u5264\u5316\u5b66\u7642\u6cd5\u5f8c\u306e\u518d\u767a\u307e\u305f\u306f\u96e3\u6cbb\u4f8b<\/li>\n<li><strong>\u5c3f\u8def\u4e0a\u76ae\u304c\u3093<\/strong> \u2014 \u30b7\u30b9\u30d7\u30e9\u30c1\u30f3\u4e0d\u9069\u683c\u4f8b\u306b\u304a\u3051\u308b\u4e00\u6b21\u8ee2\u79fb\u6cbb\u7642\uff1b\u30d7\u30e9\u30c1\u30ca\u7cfb\u5316\u5b66\u7642\u6cd5\u5f8c\u306e\u4e8c\u6b21\u6cbb\u7642\uff1b\u9ad8\u30ea\u30b9\u30af\u975e\u7b4b\u5c64\u6d78\u6f64\u6027\u8180\u80f1\u304c\u3093\uff08BCG\u4e0d\u5fdc\uff09<\/li>\n<li><strong>MSI-H\uff0fdMMR\u56fa\u5f62\u304c\u3093<\/strong> \u2014 MSI-High\u307e\u305f\u306f\u30df\u30b9\u30de\u30c3\u30c1\u4fee\u5fa9\u6a5f\u69cb\u6b20\u640d\u3092\u6709\u3059\u308b\u3059\u3079\u3066\u306e\u56fa\u5f62\u304c\u3093\u306b\u5bfe\u3059\u308b\u3001\u816b\u760d\u7a2e\u3092\u554f\u308f\u306a\u3044\u9069\u5fdc\uff1b\u7279\u306b\u5927\u8178\u304c\u3093\u3001\u5b50\u5bae\u4f53\u304c\u3093\u3001\u80c3\u304c\u3093\u306b\u304a\u3044\u3066\u91cd\u8981<\/li>\n<li><strong>\u80c3\u304c\u3093\u304a\u3088\u3073\u80c3\u98df\u9053\u63a5\u5408\u90e8\u304c\u3093<\/strong> \u2014 \u4e00\u6b21HER2\u967d\u6027\uff08\u5316\u5b66\u7642\u6cd5\u4f75\u7528\uff09\u304a\u3088\u3073HER2\u9670\u6027\uff08\u5316\u5b66\u7642\u6cd5\u4f75\u7528\uff09<\/li>\n<li><strong>\u98df\u9053\u304c\u3093<\/strong><\/li>\n<li><strong>\u5b50\u5bae\u9838\u304c\u3093<\/strong> \u2014 \u4e00\u6b21PD-L1\u967d\u6027\u306e\u6301\u7d9a\u6027\u3001\u518d\u767a\u6027\u307e\u305f\u306f\u8ee2\u79fb\u6027\u5b50\u5bae\u9838\u304c\u3093\uff08\u5316\u5b66\u7642\u6cd5\u00b1\u30d9\u30d0\u30b7\u30ba\u30de\u30d6\u4f75\u7528\uff09<\/li>\n<li><strong>\u809d\u7d30\u80de\u304c\u3093\uff08\u809d\u81d3\uff09<\/strong><\/li>\n<li><strong>\u814e\u7d30\u80de\u304c\u3093<\/strong> \u2014 \u30a2\u30ad\u30b7\u30c1\u30cb\u30d6\u307e\u305f\u306f\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u3068\u306e\u4f75\u7528\u306b\u3088\u308b\u4e00\u6b21\u6cbb\u7642<\/li>\n<li><strong>\u5b50\u5bae\u4f53\u304c\u3093<\/strong> \u2014 pMMR\uff08\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u4f75\u7528\uff09\u304a\u3088\u3073dMMR\/MSI-H\uff08\u5358\u5264\u7642\u6cd5\uff09<\/li>\n<li><strong>\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\uff08TNBC\uff09<\/strong> \u2014 \u9ad8\u30ea\u30b9\u30af\u65e9\u671f\u30b9\u30c6\u30fc\u30b8\u306b\u5bfe\u3059\u308b\u8853\u524d\u88dc\u52a9\u7642\u6cd5\uff08\u5316\u5b66\u7642\u6cd5\u4f75\u7528\uff09\u304a\u3088\u3073\u8ee2\u79fb\u6027PD-L1\u967d\u6027\uff08CPS \u2265 10\uff09<\/li>\n<li><strong>\u76ae\u819a\u6709\u68d8\u7d30\u80de\u304c\u3093<\/strong>, \u3001\u30e1\u30eb\u30b1\u30eb\u7d30\u80de\u304c\u3093\u3001\u539f\u767a\u6027\u7e26\u9694\u5927\u7d30\u80de\u578bB\u7d30\u80de\u30ea\u30f3\u30d1\u816b\u3001\u304a\u3088\u3073\u8907\u6570\u306e\u5e0c\u5c11\u306a\u816b\u760d\u6a2a\u65ad\u7684\u9069\u5fdc\u75c7<\/li>\n<\/ul>\n<p>\u9069\u5207\u306aKeytruda\u306e\u9069\u5fdc\u75c7\u3068\u4f75\u7528\u7642\u6cd5\u306f\u3001\u816b\u760d\u306e\u7a2e\u985e\u3001\u75c5\u671f\u3001\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u72b6\u614b\uff08PD-L1 TPS\u307e\u305f\u306fCPS\u3001MSI\/dMMR\u3001TMB\u3001HER2\uff09\u3001\u304a\u3088\u3073\u524d\u6cbb\u7642\u6b74\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002 <strong>\u3053\u308c\u306f\u3001\u75c5\u7406\u691c\u67fb\u3068\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u691c\u67fb\u306e\u7d50\u679c\u304c\u5b8c\u4e86\u3057\u305f\u5f8c\u306b\u3001\u5c02\u9580\u306e\u816b\u760d\u533b\u304c\u5224\u65ad\u3059\u308b\u3082\u306e\u3067\u3059\u3002<\/strong><\/p>\n<h2 class=\"wp-block-heading\">Keytruda\u306e\u7528\u6cd5\u30fb\u7528\u91cf<\/h2>\n<p>\u6a19\u6e96\u7684\u306a\u6210\u4eba\u7528\u91cf\uff1a<\/p>\n<ul>\n<li><strong>200 mg\u30923\u9031\u9593\u3054\u3068\u306b\u70b9\u6ef4\u9759\u6ce8<\/strong> \uff08\u5f53\u521d\u306e\u6295\u4e0e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\uff09\u307e\u305f\u306f<\/li>\n<li><strong>400 mg\u30926\u9031\u9593\u3054\u3068\u306b\u70b9\u6ef4\u9759\u6ce8<\/strong> \uff08Q6W\u56fa\u5b9a\u7528\u91cf\u6295\u4e0e \u2014 \u540c\u7b49\u306e\u6709\u52b9\u6027\u3067\u53d7\u8a3a\u983b\u5ea6\u3092\u4f4e\u6e1b\uff09<\/li>\n<li>\u5c0f\u5150\u7528\u91cf\uff1a2 mg\/kg\uff08\u6700\u5927200 mg\uff09\u30923\u9031\u9593\u3054\u3068\u306b\u9759\u8108\u5185\u6295\u4e0e<\/li>\n<li>\u5404\u6ce8\u5165\u306e\u6240\u8981\u6642\u9593\uff1a <strong>30\u5206<\/strong> 0.2\uff5e5 \u00b5m\u306e\u30a4\u30f3\u30e9\u30a4\u30f3\u30d5\u30a3\u30eb\u30bf\u30fc\u3092\u4f7f\u7528<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\">Keytruda\u306e\u6295\u4e0e\u65b9\u6cd5<\/h3>\n<ol>\n<li><strong>\u75c5\u9662\u307e\u305f\u306f\u816b\u760d\u79d1\u30c7\u30a4\u30e6\u30cb\u30c3\u30c8\u306e\u307f\u3067\u306e\u6295\u4e0e\u3068\u306a\u308a\u307e\u3059\u3002<\/strong> Keytruda\u306f\u3001\u5c02\u9580\u306e\u816b\u760d\u533b\u306e\u76e3\u7763\u4e0b\u3067\u3001\u8a13\u7df4\u3092\u53d7\u3051\u305f\u770b\u8b77\u5e2b\u307e\u305f\u306f\u533b\u7642\u30b9\u30bf\u30c3\u30d5\u306b\u3088\u3063\u3066\u6295\u4e0e\u3055\u308c\u307e\u3059\u3002\u81ea\u5df1\u6295\u4e0e\u3084\u5728\u5b85\u6295\u4e0e\u306f\u4e00\u5207\u884c\u308f\u308c\u307e\u305b\u3093\u3002<\/li>\n<li><strong>\u6295\u4e0e\u524d\u306e\u691c\u67fb<\/strong> \u5404\u30b5\u30a4\u30af\u30eb\u3054\u3068\uff1a\u5168\u8840\u7403\u8a08\u7b97\u3001\u5305\u62ec\u7684\u4ee3\u8b1d\u30d1\u30cd\u30eb\uff08\u809d\u6a5f\u80fd\u691c\u67fb\u3001\u814e\u6a5f\u80fd\uff09\u30016\u9031\u9593\u3054\u3068\u306b\u7532\u72b6\u817a\u6a5f\u80fd\uff08TSH\u3001\u904a\u96e2T4\uff09\u3001\u8840\u7cd6\u5024\u3002\u65b0\u305f\u306a\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u306e\u75c7\u72b6\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3002<\/li>\n<li><strong>\u901a\u5e38\u3001\u524d\u6295\u85ac\u306f\u5fc5\u8981\u3042\u308a\u307e\u305b\u3093\u3002<\/strong> \u2014 \u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u901a\u5e38\u306e\u5316\u5b66\u7642\u6cd5\u306b\u3088\u308b\u60aa\u5fc3\u3084\u904e\u654f\u75c7\u53cd\u5fdc\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u305b\u3093\u3002\u5236\u5410\u5264\u306f\u4e0d\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u30d0\u30a4\u30a2\u30eb\u306e\u8abf\u88fd\u65b9\u6cd5\uff1a<\/strong> \u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u3092\u751f\u7406\u98df\u5869\u6c34\u307e\u305f\u306f5%\u30d6\u30c9\u30a6\u7cd6\u6db2\u3067\u5e0c\u91c8\u3057\u3001\u6700\u7d42\u6fc3\u5ea61\uff5e10 mg\/mL\u306b\u8abf\u6574\u3057\u307e\u3059\u3002\u8abf\u88fd\u5f8c\u3001\u5ba4\u6e29\u4fdd\u5b58\u306e\u5834\u5408\u306f6\u6642\u9593\u4ee5\u5185\u3001\u51b7\u8535\u4fdd\u5b58\u306e\u5834\u5408\u306f24\u6642\u9593\u4ee5\u5185\u306b\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>30\u5206\u9593\u306e\u9759\u8108\u5185\u6ce8\u5165<\/strong> 0.2\uff5e5 \u00b5m\u306e\u30a4\u30f3\u30e9\u30a4\u30f3\u30d5\u30a3\u30eb\u30bf\u30fc\u3092\u4ecb\u3057\u3066\u6295\u4e0e\u3057\u307e\u3059\u3002IV\u30d7\u30c3\u30b7\u30e5\u307e\u305f\u306f\u30dc\u30fc\u30e9\u30b9\u6295\u4e0e\u306f\u884c\u308f\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u6cbb\u7642\u30b5\u30a4\u30af\u30eb\u983b\u5ea6<\/strong> \u4e88\u5b9a\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\uff08Q3W\u307e\u305f\u306fQ6W\uff09\u3067\u6295\u4e0e\u3057\u3001\u75c5\u52e2\u9032\u884c\u3001\u8a31\u5bb9\u3067\u304d\u306a\u3044\u6bd2\u6027\u3001\u307e\u305f\u306f\u8a08\u753b\u3055\u308c\u305f\u6cbb\u7642\u671f\u9593\u306e\u5b8c\u4e86\uff08\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u7642\u6cd5\u3067\u306f\u901a\u5e3824\u304b\u6708\u3001\u8ee2\u79fb\u6027\u3067\u306f\u9032\u884c\u307e\u3067\uff09\u307e\u3067\u7d99\u7d9a\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u5fc5\u9808\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/strong> \u5404\u6765\u9662\u6642\u306b\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAE\uff09\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\uff1a\u76ae\u819a\uff08\u767a\u75b9\u3001\u767d\u6591\u3001\u76ae\u819a\u708e\uff09\u3001\u6d88\u5316\u5668\uff08\u4e0b\u75e2\u3001\u8179\u75db\uff09\u3001\u547c\u5438\u5668\uff08\u54b3\u55fd\u3001\u547c\u5438\u56f0\u96e3\uff09\u3001\u5185\u5206\u6ccc\uff08\u75b2\u52b4\u3001\u4f53\u91cd\u5909\u5316\u3001\u7532\u72b6\u817a\u708e\u307e\u305f\u306f\u4e0b\u5782\u4f53\u708e\u306b\u3088\u308b\u52d5\u60b8\uff09\u3001\u809d\u81d3\uff08\u9ec4\u75b8\uff09\u3001\u814e\u81d3\uff08\u30af\u30ec\u30a2\u30c1\u30cb\u30f3\uff09\u3001\u795e\u7d4c\uff08\u8131\u529b\u611f\u3001\u611f\u899a\u7570\u5e38\uff09\u3002<\/li>\n<li><strong>\u6c38\u7d9a\u7684\u4e2d\u6b62<\/strong> \u30b0\u30ec\u30fc\u30c93\uff5e4\u306e\u80ba\u81d3\u708e\u3001\u809d\u708e\u3001\u814e\u708e\u3001\u76ae\u819a\u708e\u3001\u795e\u7d4c\u6bd2\u6027\u3001\u5fc3\u7b4b\u708e\u306eirAE\uff1b\u3044\u305a\u308c\u304b\u306e\u81d3\u5668\u3067\u518d\u767a\u3059\u308b\u30b0\u30ec\u30fc\u30c92\uff5e3\u306eirAE\uff1b\u307e\u305f\u306f\u30b0\u30ec\u30fc\u30c94\u306eirAE\u3002<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Keytruda\u306e\u526f\u4f5c\u7528<\/h2>\n<p>\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u3001\u7d30\u80de\u50b7\u5bb3\u6027\u5316\u5b66\u7642\u6cd5\u3068\u306f\u6839\u672c\u7684\u306b\u7570\u306a\u308b\u6bd2\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6709\u3057\u307e\u3059\u3002\u4e3b\u306a\u526f\u4f5c\u7528\u306e\u30ab\u30c6\u30b4\u30ea\u30fc\u306f\u3001 <strong>\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAE\uff09<\/strong> \u2014\u6b63\u5e38\u7d44\u7e54\u306b\u5bfe\u3059\u308b\u5236\u5fa1\u4e0d\u80fd\u306a\u514d\u75ab\u6d3b\u6027\u306b\u3088\u3063\u3066\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u81ea\u5df1\u514d\u75ab\u69d8\u53cd\u5fdc\u3002<\/p>\n<p><strong>\u4e00\u822c\uff08\u975eirAE\uff09\uff1a<\/strong> \u75b2\u52b4\u3001\u98df\u6b32\u4f4e\u4e0b\u3001\u60aa\u5fc3\uff08\u8efd\u5ea6\uff09\u3001\u4fbf\u79d8\u3001\u4e0b\u75e2\u3001\u95a2\u7bc0\u75db\u3001\u305d\u3046\u75d2\u75c7\u3001\u767a\u75b9\u3001\u8efd\u5ea6\u306e\u982d\u75db\u3002<\/p>\n<p><strong>\u4e00\u822c\u7684\u306a\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAEs\uff09\uff1a<\/strong><\/p>\n<ul>\n<li><strong>\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7<\/strong> \uff0810\uff5e15%\uff09\u304a\u3088\u3073\u7532\u72b6\u817a\u6a5f\u80fd\u4ea2\u9032\u75c7\uff084\uff5e6%\uff09\u2014 \u514d\u75ab\u7532\u72b6\u817a\u708e\u306b\u3088\u308b\u3002\u901a\u5e38\u3001\u751f\u6daf\u306b\u308f\u305f\u308b\u30ec\u30dc\u30c1\u30ed\u30ad\u30b7\u30f3\u6295\u4e0e\u304c\u5fc5\u8981\u3067\u3059\u3002TSH\u306f6\u9031\u9593\u3054\u3068\u306b\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u76ae\u819a\u53cd\u5fdc<\/strong> \u2014 \u767a\u75b9\u3001\u305d\u3046\u75d2\u75c7\u3001\u767d\u6591\u3001\u82d4\u766c\u69d8\u76ae\u75b9\u30021\uff5e3%\u3067\u91cd\u5ea6\u3002<\/li>\n<li><strong>\u4e0b\u75e2\/\u5927\u8178\u708e<\/strong> \u2014 1\uff5e3%\u3067\u91cd\u5ea6\u3002\u672a\u6cbb\u7642\u306e\u5834\u5408\u3001\u8178\u7a7f\u5b54\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u80ba\u81d3\u708e<\/strong> \uff08\u5168\u30b0\u30ec\u30fc\u30c9\u7d043%\u3001\u91cd\u5ea6&lt;1%\uff09\u2014 \u65b0\u305f\u306a\u547c\u5438\u56f0\u96e3\u307e\u305f\u306f\u54b3\u304c\u3042\u308c\u3070\u7dca\u6025\u306e\u80f8\u90e8CT\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u809d\u708e<\/strong> \uff08\u91cd\u5ea6\u7d041%\uff09\u2014 LFT\u4e0a\u6607\u3002<\/li>\n<li><strong>\u526f\u814e\u4e0d\u5168\u3001\u4e0b\u5782\u4f53\u708e<\/strong> \u2014 \u75b2\u52b4\u3001\u4f4e\u8840\u5727\u3001\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7\u3002\u751f\u6daf\u306b\u308f\u305f\u308b\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\u88dc\u5145\u304c\u5fc5\u8981\u3068\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<li><strong>1\u578b\u7cd6\u5c3f\u75c5<\/strong> \u2014 \u65b0\u898f\u767a\u75c7\u306e\u30b1\u30c8\u30a2\u30b7\u30c9\u30fc\u30b7\u30b9\u3002\u307b\u3068\u3093\u3069\u4e0d\u53ef\u9006\u7684\u3067\u3001\u751f\u6daf\u30a4\u30f3\u30b9\u30ea\u30f3\u6cbb\u7642\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u814e\u708e<\/strong> \u2014 \u30af\u30ec\u30a2\u30c1\u30cb\u30f3\u4e0a\u6607\u3002<\/li>\n<\/ul>\n<p><strong>\u307e\u308c\u3067\u306f\u3042\u308b\u304c\u91cd\u8981\u306a\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAE\uff09\uff1a<\/strong> \u5fc3\u7b4b\u708e\uff08\u307e\u308c\u3067\u3059\u304c\u6b7b\u4ea1\u7387\u304c\u9ad8\u3044\uff09\u3001\u672b\u68a2\u795e\u7d4c\u969c\u5bb3\u30fb\u8133\u795e\u7d4c\u969c\u5bb3\u3001\u30ae\u30e9\u30f3\u30fb\u30d0\u30ec\u30fc\u75c7\u5019\u7fa4\u3001\u91cd\u75c7\u7b4b\u7121\u529b\u75c7\u3001\u8133\u708e\u3001\u30ea\u30a6\u30de\u30c1\u6027\u591a\u767a\u7b4b\u75db\u75c7\u3001\u3076\u3069\u3046\u819c\u708e\u3001\u91cd\u5ea6\u306e\u76ae\u819a\u53cd\u5fdc\uff08\u30b9\u30c6\u30a3\u30fc\u30d6\u30f3\u30b9\u30fb\u30b8\u30e7\u30f3\u30bd\u30f3\u75c7\u5019\u7fa4\u3001\u4e2d\u6bd2\u6027\u8868\u76ae\u58ca\u6b7b\u75c7\uff09\u3001\u6eb6\u8840\u6027\u8ca7\u8840\u3001\u8840\u7403\u6e1b\u5c11\u75c7\u304c\u542b\u307e\u308c\u307e\u3059\u3002<\/p>\n<p><strong>irAE\uff08\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff09\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u306e\u57fa\u672c\u539f\u5247\uff1a<\/strong> \u30b0\u30ec\u30fc\u30c91\u3067\u306f\u652f\u6301\u7642\u6cd5\u3068\u7d4c\u904e\u89b3\u5bdf\u3001\u30b0\u30ec\u30fc\u30c92\u3067\u306f\u6cbb\u7642\u306e\u4e00\u6642\u4e2d\u6b62\uff0b\u5168\u8eab\u6027\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\uff08\u30d7\u30ec\u30c9\u30cb\u30be\u30f30.5\uff5e1 mg\/kg\uff09\u3092\u958b\u59cb\u3001\u30b0\u30ec\u30fc\u30c93\uff5e4\u3067\u306f\u6cbb\u7642\u306e\u4e00\u6642\u4e2d\u6b62\u307e\u305f\u306f\u6c38\u7d9a\u7684\u4e2d\u6b62\uff0b\u9ad8\u7528\u91cf\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\uff081\uff5e2 mg\/kg\uff09\uff0b\u5185\u5206\u6ccc\u79d1\uff0f\u6d88\u5316\u5668\u79d1\uff0f\u547c\u5438\u5668\u79d1\uff0f\u5faa\u74b0\u5668\u79d1\u306e\u5c02\u9580\u533b\u306b\u3088\u308b\u8a55\u4fa1\u3092\u9069\u5b9c\u884c\u3044\u307e\u3059\u3002\u307b\u3068\u3093\u3069\u306eirAE\u306f\u9069\u5207\u306a\u30b9\u30c6\u30ed\u30a4\u30c9\u7642\u6cd5\u306b\u3088\u308a\u6539\u5584\u3057\u307e\u3059\u3002\u5185\u5206\u6ccc\u969c\u5bb3\uff08\u7532\u72b6\u817a\u3001\u526f\u814e\u30011\u578b\u7cd6\u5c3f\u75c5\uff09\u306f\u901a\u5e38\u6c38\u7d9a\u7684\u3067\u3042\u308a\u3001\u751f\u6daf\u306b\u308f\u305f\u308b\u30db\u30eb\u30e2\u30f3\u88dc\u5145\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n<h2 class=\"wp-block-heading\">\u8b66\u544a\u304a\u3088\u3073\u4f7f\u7528\u4e0a\u306e\u6ce8\u610f<\/h2>\n<ul>\n<li><strong>\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAE\uff09\uff1a<\/strong> \u3042\u3089\u3086\u308b\u81d3\u5668\u7cfb\u7d71\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u6cbb\u7642\u4e2d\uff08\u6cbb\u7642\u7d42\u4e86\u5f8c\u6570\u304b\u6708\u9593\u3092\u542b\u3080\uff09\u306e\u3044\u3064\u3067\u3082\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u60a3\u8005\u3055\u3093\u3068\u4ecb\u8b77\u8005\u3078\u306eirAE\u75c7\u72b6\u306b\u95a2\u3059\u308b\u6559\u80b2\u304c\u5fc5\u9808\u3067\u3059\u3002\u4ee5\u4e0b\u306e\u75c7\u72b6\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u5f53\u65e5\u4e2d\u306e\u53d7\u8a3a\u304c\u5fc5\u8981\u3067\u3059\uff1a\u91cd\u5ea6\u306e\u4e0b\u75e2\uff08\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3088\u308a4\u56de\u4ee5\u4e0a\u306e\u6392\u4fbf\u5897\u52a0\uff09\u3001\u65b0\u305f\u306a\u606f\u5207\u308c\u3001\u4f4e\u8840\u5727\u3092\u4f34\u3046\u91cd\u5ea6\u306e\u5026\u6020\u611f\u3001\u9ec4\u75b8\u3001\u91cd\u5ea6\u306e\u8179\u75db\u3001\u80f8\u75db\u3001\u8131\u529b\u611f\u307e\u305f\u306f\u3057\u3073\u308c\u3001\u91cd\u5ea6\u306e\u76ae\u75b9\u3001\u65b0\u305f\u306a\u982d\u75db\u3068\u8996\u899a\u306e\u5909\u5316\u3002<\/li>\n<li><strong>\u65e2\u5b58\u306e\u81ea\u5df1\u514d\u75ab\u75be\u60a3<\/strong> \uff08\u4f8b\uff1a\u708e\u75c7\u6027\u8178\u75be\u60a3\u3001\u30eb\u30fc\u30d7\u30b9\u3001\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3001\u4e7e\u766c\u3001\u591a\u767a\u6027\u786c\u5316\u75c7\u30011\u578b\u7cd6\u5c3f\u75c5\uff09\uff1aKeytruda\uff08\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\uff09\u306f\u3053\u308c\u3089\u306e\u57fa\u790e\u75be\u60a3\u3092\u91cd\u7be4\u306b\u60aa\u5316\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u816b\u760d\u5c02\u9580\u533b\u3068\u95a2\u9023\u3059\u308b\u5c02\u9580\u533b\u306b\u3088\u308b\u30ea\u30b9\u30af\u3068\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u306e\u5224\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u56fa\u5f62\u81d3\u5668\u307e\u305f\u306f\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u3092\u53d7\u3051\u305f\u65b9\uff1a<\/strong> Keytruda\uff08\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\uff09\u306f\u79fb\u690d\u62d2\u7d76\u53cd\u5fdc\u3084\u79fb\u690d\u7247\u5bfe\u5bbf\u4e3b\u75c5\u3092\u8a98\u767a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u5c02\u9580\u533b\u306b\u3088\u308b\u76e3\u7763\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u598a\u5a20\u4e2d\uff1a<\/strong> \u7981\u5fcc\uff1a\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u80ce\u76e4\u3092\u901a\u904e\u3057\u3001\u80ce\u5150\u306e\u514d\u75ab\u5bdb\u5bb9\u3092\u59a8\u3052\u3001\u6b7b\u7523\u3084\u81ea\u5df1\u514d\u75ab\u5408\u4f75\u75c7\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u6cbb\u7642\u4e2d\u304a\u3088\u3073\u6700\u7d42\u6295\u4e0e\u5f8c4\u304b\u6708\u9593\u306f\u78ba\u5b9f\u306a\u907f\u598a\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u6388\u4e73\u4e2d\uff1a<\/strong> \u6388\u4e73\u306f\u907f\u3051\u308b \u2014 \u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u304c\u6bcd\u4e73\u4e2d\u306b\u6392\u6cc4\u3055\u308c\u307e\u3059\u3002\u6700\u7d42\u6295\u4e0e\u5f8c4\u304b\u6708\u9593\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u751f\u30ef\u30af\u30c1\u30f3\uff1a<\/strong> \u7981\u5fcc\u3067\u3059\u3002<\/li>\n<li><strong>\u6d3b\u52d5\u6027\u611f\u67d3\u75c7\uff1a<\/strong> \u91cd\u7be4\u306a\u611f\u67d3\u75c7\u306e\u9593\u306f\u6cbb\u7642\u3092\u4e00\u6642\u4e2d\u65ad\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u91cd\u5ea6\u306e\u809d\u6a5f\u80fd\u969c\u5bb3\uff0f\u814e\u6a5f\u80fd\u969c\u5bb3\uff1a<\/strong> \u9650\u3089\u308c\u305f\u30c7\u30fc\u30bf; \u5c02\u9580\u533b\u306e\u5224\u65ad\u3002<\/li>\n<li><strong>\u30b3\u30fc\u30eb\u30c9\u30c1\u30a7\u30fc\u30f3\u4fdd\u7ba1:<\/strong> \u30d0\u30a4\u30a2\u30eb\u306f2\uff5e8\u2103\u3067\u51b7\u8535\u3057\u3001\u51cd\u7d50\u3055\u305b\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u30b3\u30fc\u30eb\u30c9\u30c1\u30a7\u30fc\u30f3\u304c\u9014\u7d76\u3048\u305f\u5834\u5408\u3001\u30d0\u30a4\u30a2\u30eb\u306f\u7121\u52b9\u3068\u306a\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u8cbb\u7528\u3068\u511f\u9084:<\/strong> Keytruda\uff08\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\uff09\u306f\u6700\u3082\u9ad8\u4fa1\u306a\u304c\u3093\u6cbb\u7642\u85ac\u306e1\u3064\u3067\u3059\uff08\u5148\u767a\u54c1\u4fa1\u683c\u30671\u56de\u6295\u4e0e\u3042\u305f\u308a\u7d0410,000\uff5e14,000\u7c73\u30c9\u30eb\uff09\u3002\u60a3\u8005\u30a2\u30af\u30bb\u30b9\u30d7\u30ed\u30b0\u30e9\u30e0\u3001\u5229\u7528\u53ef\u80fd\u306a\u5834\u5408\u306f\u30d0\u30a4\u30aa\u30b7\u30df\u30e9\u30fc\u306e\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u3001\u539f\u7523\u56fd\u306e\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u3067\u306f\u3001\u4fa1\u683c\u304c\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059\u3002<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u7981\u5fcc<\/h2>\n<ul>\n<li>\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u307e\u305f\u306f\u30d0\u30a4\u30a2\u30eb\u306e\u6dfb\u52a0\u5264\u306b\u5bfe\u3059\u308b\u904e\u654f\u75c7\u306e\u65e2\u5f80<\/li>\n<li>\u598a\u5a20\u4e2d\u307e\u305f\u306f\u598a\u5a20\u3092\u8a08\u753b\u3057\u3066\u3044\u308b<\/li>\n<li>\u6388\u4e73\u4e2d<\/li>\n<li>\u91cd\u5ea6\u306e\u65e2\u5f80\u81ea\u5df1\u514d\u75ab\u75be\u60a3\uff08\u76f8\u5bfe\u7684\u7981\u5fcc; \u5c02\u9580\u533b\u306e\u5224\u65ad\uff09<\/li>\n<li>\u56fa\u5f62\u81d3\u5668\u79fb\u690d\u306e\u30ec\u30b7\u30d4\u30a8\u30f3\u30c8\uff08\u76f8\u5bfe\u7684\u7981\u5fcc; \u5c02\u9580\u533b\u306e\u5224\u65ad; \u79fb\u690d\u62d2\u7d76\u53cd\u5fdc\u306e\u30ea\u30b9\u30af\uff09<\/li>\n<li>\u5236\u5fa1\u4e0d\u80fd\u306a\u6d3b\u52d5\u6027\u611f\u67d3\u75c7<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u85ac\u7269\u76f8\u4e92\u4f5c\u7528<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;\">\u4f75\u7528<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">\u52b9\u679c<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;\">\u5bfe\u51e6\u6cd5<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u5168\u8eab\u6027\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\uff08\u6162\u6027\u3001\u30d7\u30ec\u30c9\u30cb\u30be\u30f310 mg\/\u65e5\u4ee5\u4e0a\u76f8\u5f53\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u514d\u75ab\u5fdc\u7b54\u3092\u6291\u5236\u3057\u3001Keytruda\u304c\u5897\u5f37\u3057\u3088\u3046\u3068\u3059\u308b\u4f5c\u7528\u3092\u5f31\u3081\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u2014 \u6709\u52b9\u6027\u304c\u4f4e\u4e0b\u3059\u308b\u6050\u308c\u304c\u3042\u308a\u307e\u3059\u3002<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u53ef\u80fd\u3067\u3042\u308c\u3070\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u6162\u6027\u30b9\u30c6\u30ed\u30a4\u30c9\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002irAE\uff08\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff09\u7ba1\u7406\u3084\u4ed6\u306e\u9069\u5fdc\u75c7\u306e\u305f\u3081\u306e\u77ed\u671f\u6295\u4e0e\u306f\u9069\u5207\u3067\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u305d\u306e\u4ed6\u306e\u514d\u75ab\u6291\u5236\u5264\uff08\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u3001\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u3001\u30a2\u30b6\u30c1\u30aa\u30d7\u30ea\u30f3\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u4e0a\u8a18\u3068\u540c\u69d8\u306b\u3001Keytruda\u306e\u6709\u52b9\u6027\u304c\u4f4e\u4e0b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u5c02\u9580\u533b\u306e\u8a55\u4fa1\u304c\u5fc5\u8981\u3067\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u751f\u30ef\u30af\u30c1\u30f3\uff08MMR\u3001\u9ec4\u71b1\u3001BCG\u3001\u7d4c\u53e3\u30dd\u30ea\u30aa\u3001\u6c34\u75d8\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u751f\u30ef\u30af\u30c1\u30f3\u30a6\u30a4\u30eb\u30b9\u306b\u3088\u308b\u64ad\u7a2e\u6027\u611f\u67d3\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Keytruda\u6cbb\u7642\u4e2d\u304a\u3088\u3073\u6cbb\u7642\u5f8c\u6570\u304b\u6708\u9593\u306f\u7981\u5fcc\u3067\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u4e0d\u6d3b\u5316\u30ef\u30af\u30c1\u30f3\uff08\u6bce\u5e74\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3001\u80ba\u708e\u7403\u83cc\u3001COVID-19\u3001B\u578b\u809d\u708e\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u5b89\u5168\u3067\u3042\u308a\u3001\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u6a19\u6e96\u7684\u306a\u8a3a\u7642\u3067\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u4f75\u7528\u5316\u5b66\u7642\u6cd5\uff08\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\uff0f\u30d1\u30af\u30ea\u30bf\u30ad\u30bb\u30eb\u3001\u30ec\u30f3\u30d0\u30c1\u30cb\u30d6\u3001\u30a2\u30ad\u30b7\u30c1\u30cb\u30d6\u3001\u305d\u306e\u4ed6\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u591a\u304f\u306e\u9069\u5fdc\u75c7\u3067\u6a19\u6e96\u7684\u306a\u4f75\u7528\u7642\u6cd5\u3067\u3042\u308a\u3001\u76f8\u52a0\u7684\u306a\u6709\u52b9\u6027\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u5c02\u9580\u533b\u304c\u30ec\u30b8\u30e1\u30f3\u306b\u5fdc\u3058\u3066\u5224\u65ad\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">CTLA-4\u963b\u5bb3\u85ac\uff08\u30a4\u30d4\u30ea\u30e0\u30de\u30d6\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">PD-1\u3068CTLA-4\u306e\u4f75\u7528\u906e\u65ad\u7642\u6cd5\u306f\u3001\u4e00\u90e8\u306e\u9069\u5fdc\u75c7\u3067\u594f\u52b9\u7387\u3092\u5411\u4e0a\u3055\u305b\u307e\u3059\u304c\u3001irAE\u306e\u30ea\u30b9\u30af\u304c\u8457\u3057\u304f\u9ad8\u307e\u308a\u307e\u3059\u3002<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u5c02\u9580\u533b\u306b\u3088\u308b\u96c6\u4e2d\u7684\u306a\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u4e0b\u3067\u306e\u4f75\u7528\u7642\u6cd5\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">\u4fdd\u7ba1\u65b9\u6cd5<\/h2>\n<ul>\n<li>\u672a\u958b\u5c01\u306e\u30d0\u30a4\u30a2\u30eb\u306f <strong>2\uff5e8\u00b0C<\/strong> \u76f4\u5c04\u65e5\u5149\u3092\u907f\u3051\u3001\u5143\u306e\u30ab\u30fc\u30c8\u30f3\u306b\u5165\u308c\u3066. <strong>\u51cd\u7d50\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/strong><\/li>\n<li>\u30d0\u30a4\u30a2\u30eb\u3092\u632f\u3089\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u5e0c\u91c8\u3057\u305f\u8f38\u6db2\uff1a\u51b7\u8535\u306724\u6642\u9593\u3001\u5ba4\u6e29\u30676\u6642\u9593\u5b89\u5b9a\u3002\u51cd\u7d50\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u30b3\u30fc\u30eb\u30c9\u30c1\u30a7\u30fc\u30f3\u304c\u9014\u7d76\u3048\u305f\u5834\u5408\uff088\u2103\u8d85\u306724\u6642\u9593\u4ee5\u4e0a\uff09\u3001\u30d0\u30a4\u30a2\u30eb\u306f\u7121\u52b9\u3068\u306a\u308a\u307e\u3059\u306e\u3067\u4f7f\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u304a\u5b50\u69d8\u3084\u30da\u30c3\u30c8\u306e\u624b\u306e\u5c4a\u304b\u306a\u3044\u5834\u6240\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u672a\u4f7f\u7528\u306e\u30d0\u30a4\u30a2\u30eb\u306f\u3001\u9069\u5207\u306b\u5ec3\u68c4\u3059\u308b\u305f\u3081\u85ac\u5c40\u307e\u305f\u306f\u816b\u760d\u79d1\u30e6\u30cb\u30c3\u30c8\u306b\u8fd4\u5374\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">MedsBase\u3067\u3054\u89a7\u3044\u305f\u3060\u3051\u308b\u95a2\u9023\u4ee3\u66ff\u54c1<\/h2>\n<p>\u672c\u88fd\u54c1\u3068\u5408\u308f\u305b\u3066\u53d6\u308a\u6271\u3063\u3066\u3044\u308b\u305d\u306e\u4ed6\u306e\u304c\u3093\u6cbb\u7642\u85ac\uff1a<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ja\/anaridex\/\"><strong>Anaridex\uff08\u30a2\u30ca\u30b9\u30c8\u30ed\u30be\u30fc\u30eb1mg\uff09<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/xtane\/\"><strong>Xtane\uff08\u30a8\u30ad\u30bb\u30e1\u30b9\u30bf\u30f3 25 mg\uff09<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/fempro\/\"><strong>Fempro\uff08\u30ec\u30c8\u30ed\u30be\u30fc\u30eb2.5mg\uff09<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/letroheal\/\"><strong>Letroheal\uff08\u30ec\u30c8\u30ed\u30be\u30fc\u30eb2.5mg\uff09<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/tamilong\/\"><strong>Tamilong\uff08\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f310\/20mg\uff09<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/tamodex\/\"><strong>Tamodex\uff08\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f310\/20mg\uff09<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/tamoxilon\/\"><strong>Tamoxilon\uff08\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3 10 \/ 20 mg\uff09<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/cytotam\/\"><strong>Cytotam\uff08\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3 10 \/ 20 mg\uff09<\/strong><\/a><\/li>\n<\/ul>\n<p><a href=\"https:\/\/medsbase.com\/ja\/anti-cancer-medication\/\">\u3059\u3079\u3066\u306e\u6297\u304c\u3093\u5264\u3092\u898b\u308b \u2192<\/a><\/p>\n<h2 id=\"faqs\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n<h3 class=\"wp-block-heading\">Keytruda\u306f\u5316\u5b66\u7642\u6cd5\u3068\u3069\u306e\u3088\u3046\u306b\u7570\u306a\u308a\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u5316\u5b66\u7642\u6cd5\u306f\u3001\u6025\u901f\u306b\u5206\u88c2\u3059\u308b\u7d30\u80de\uff08\u304c\u3093\u7d30\u80de\u3060\u3051\u3067\u306a\u304f\u3001\u9aa8\u9ac4\u3001\u6bdb\u5305\u3001\u6d88\u5316\u7ba1\u7c98\u819c\u306a\u3069\uff09\u3092\u76f4\u63a5\u6bba\u50b7\u3059\u308b\u305f\u3081\u3001\u9aa8\u9ac4\u6291\u5236\u3001\u8131\u6bdb\u3001\u7c98\u819c\u708e\u3001\u60aa\u5fc3\u3068\u3044\u3063\u305f\u5178\u578b\u7684\u306a\u526f\u4f5c\u7528\u30d1\u30bf\u30fc\u30f3\u304c\u751f\u3058\u307e\u3059\u3002Keytruda <strong>\u60a3\u8005\u81ea\u8eab\u306e\u514d\u75ab\u7cfb\u3092\u6d3b\u6027\u5316\u3057\u3001\u304c\u3093\u3092\u8a8d\u8b58\u30fb\u7834\u58ca\u3055\u305b\u307e\u3059\u3002<\/strong> \u2014 \u76f4\u63a5\u7d30\u80de\u3092\u6bba\u50b7\u3059\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u305f\u304c\u3063\u3066\u526f\u4f5c\u7528\u306f\u6839\u672c\u7684\u306b\u7570\u306a\u308a\u3001\u4e3b\u4f53\u306f <strong>\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAE\uff09<\/strong> \u2014 \u3042\u3089\u3086\u308b\u81d3\u5668\u7cfb\u306b\u751f\u3058\u308b\u81ea\u5df1\u514d\u75ab\u69d8\u53cd\u5fdc\u3067\u3059\u3002Keytruda\u3092\u6295\u4e0e\u3055\u308c\u308b\u60a3\u8005\u306e\u307b\u3068\u3093\u3069\u306f\u3001\u5178\u578b\u7684\u306a\u5316\u5b66\u7642\u6cd5\u306e\u6bd2\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u7d4c\u9a13\u3057\u307e\u305b\u3093\u304c\u3001\u591a\u304f\u306e\u6cbb\u7642\u30ec\u30b8\u30e1\u30f3\u3067\u306fKeytruda\u304c\u5316\u5b66\u7642\u6cd5\u3068\u4f75\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">Keytruda\u6cbb\u7642\u306b\u304a\u3044\u3066\u3001PD-L1\u691c\u67fb\u306f\u3069\u306e\u3088\u3046\u306a\u610f\u5473\u3092\u6301\u3061\u307e\u3059\u304b\uff1f<\/h3>\n<p>PD-L1\u306f\u3001Keytruda\u306e\u4f5c\u7528\u6a5f\u5e8f\u304c\u963b\u5bb3\u3059\u308b\u304c\u3093\u7d30\u80de\u4e0a\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002\u816b\u760d\u306ePD-L1\u767a\u73fe\u306f\u3001\u751f\u691c\u7d44\u7e54\u306e\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u67d3\u8272\u3067\u6e2c\u5b9a\u3055\u308c\u3001\u5831\u544a\u3055\u308c\u307e\u3059\u3002 <strong>TPS\uff08\u816b\u760d\u6bd4\u7387\u30b9\u30b3\u30a2\uff09<\/strong> \u307e\u305f\u306f <strong>CPS\uff08\u8907\u5408\u967d\u6027\u30b9\u30b3\u30a2\uff09<\/strong>. \u3002PD-L1\u767a\u73fe\u304c\u9ad8\u3044\u307b\u3069\u3001\u4e00\u822c\u7684\u306b\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u306e\u52b9\u679c\u306f\u826f\u597d\u3067\u3042\u308a\u3001\u7279\u306b\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\uff08NSCLC\uff09\u3067\u306f\u9855\u8457\u3067\u3059\uff08TPS 50%\u4ee5\u4e0a\u2192\u4e00\u6b21\u6cbb\u7642\u306e\u5358\u5264\u7642\u6cd5\u30011\uff5e49%\u2192\u4e8c\u6b21\u6cbb\u7642\u307e\u305f\u306f\u5316\u5b66\u7642\u6cd5\u3068\u306e\u4f75\u7528\uff09\u3002\u4e00\u90e8\u306e\u9069\u5fdc\u75c7\uff08NSCLC\u3001\u80c3\u304c\u3093\u3001\u5b50\u5bae\u9838\u304c\u3093\u3001\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\uff09\u3067\u306f\u3001\u6cbb\u7642\u524d\u306bPD-L1\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002\u305d\u306e\u4ed6\u306e\u9069\u5fdc\u75c7\uff08MSI-H\/dMMR\u304c\u3093\u3001\u60aa\u6027\u9ed2\u8272\u816b\u3001\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\uff09\u3067\u306f\u3001PD-L1\u306e\u767a\u73fe\u72b6\u6cc1\u306b\u95a2\u308f\u3089\u305a\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u304c\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08irAE\uff09\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f\u307e\u305f\u3001\u306a\u305c\u305d\u308c\u307b\u3069\u91cd\u8981\u3067\u3059\u304b\uff1f<\/h3>\n<p>irAE\u306f\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u306e\u4e3b\u306a\u526f\u4f5c\u7528\u30ab\u30c6\u30b4\u30ea\u30fc\u3067\u3042\u308a\u3001\u30d6\u30ec\u30fc\u30ad\u304c\u89e3\u9664\u3055\u308c\u305f\u514d\u75ab\u7cfb\u304c\u6b63\u5e38\u7d44\u7e54\u3092\u653b\u6483\u3059\u308b\u3053\u3068\u3067\u751f\u3058\u308b\u81ea\u5df1\u514d\u75ab\u69d8\u53cd\u5fdc\u3067\u3059\u3002\u76ae\u819a\u3001\u6d88\u5316\u7ba1\uff08\u5927\u8178\u708e\uff09\u3001\u80ba\uff08\u80ba\u81d3\u708e\uff09\u3001\u809d\u81d3\uff08\u809d\u708e\uff09\u3001\u7532\u72b6\u817a\u3001\u4e0b\u5782\u4f53\u3001\u526f\u814e\u30011\u578b\u7cd6\u5c3f\u75c5\u306e\u81b5\u81d3\u3001\u814e\u81d3\u3001\u672b\u68a2\u795e\u7d4c\u3001\u5fc3\u81d3\uff08\u6b7b\u4ea1\u7387\u306e\u9ad8\u3044\u7a00\u306a\u5fc3\u7b4b\u708e\uff09\u306a\u3069\u3001\u3042\u3089\u3086\u308b\u81d3\u5668\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u306f <strong>\u6cbb\u7642\u4e2d\u306e\u3069\u306e\u6642\u70b9\u3067\u3082\u3001\u307e\u305f\u6700\u7d42\u6295\u4e0e\u304b\u3089\u6570\u304b\u6708\u5f8c\u3067\u3082\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059<\/strong>. \u3002\u91cd\u75c7\u5ea6\u306f\u30b0\u30ec\u30fc\u30c91\uff08\u8efd\u5ea6\uff09\u304b\u3089\u30b0\u30ec\u30fc\u30c94\uff08\u751f\u547d\u3092\u8105\u304b\u3059\uff09\u307e\u3067\u3042\u308a\u307e\u3059\u3002 <strong>\u65e9\u671f\u767a\u898b\u304c\u6975\u3081\u3066\u91cd\u8981\u3067\u3059<\/strong> \u2014 \u307b\u3068\u3093\u3069\u306eirAE\u306f\u3001\u8fc5\u901f\u306b\u6cbb\u7642\u3059\u308c\u3070\u5168\u8eab\u6027\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u3088\u304f\u53cd\u5fdc\u3057\u307e\u3059\u3002\u60a3\u8005\u69d8\u306f24\u6642\u9593\u5bfe\u5fdc\u306e\u816b\u760d\u79d1\u9023\u7d61\u5148\u3092\u4fdd\u6301\u3057\u3001\u65b0\u305f\u306a\u91cd\u5ea6\u306e\u4e0b\u75e2\u3001\u547c\u5438\u56f0\u96e3\u3001\u9ec4\u75b8\u3001\u91cd\u5ea6\u306e\u75b2\u52b4\u611f\u3001\u8131\u529b\u611f\u3001\u8996\u899a\u306e\u5909\u5316\u3001\u307e\u305f\u306f\u80f8\u75db\u304c\u751f\u3058\u305f\u5834\u5408\u306b\u306f\u3001\u5f53\u65e5\u4e2d\u306b\u96fb\u8a71\u9023\u7d61\u3059\u308b\u3088\u3046\u6307\u5c0e\u3092\u53d7\u3051\u308b\u3079\u304d\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u3067\u79c1\u306e\u304c\u3093\u306f\u6cbb\u308a\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u4e00\u90e8\u306e\u60a3\u8005\u69d8\u3001\u4e00\u90e8\u306e\u9069\u5fdc\u75c7\u306b\u304a\u3044\u3066\u3001\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u306f\u6a5f\u80fd\u7684\u6cbb\u7652\u306b\u8fd1\u3065\u304f\u53ef\u80fd\u6027\u306e\u3042\u308b\u6301\u7d9a\u7684\u306a\u52b9\u679c\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002\u7279\u306b\u3001\u9032\u884c\u6027\u60aa\u6027\u9ed2\u8272\u816b\u3001MSI-H\/dMMR\u304c\u3093\u3001\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u3067\u306f\u30015\u5e74\u751f\u5b58\u7387\u304c\u73fe\u5728\u304b\u306a\u308a\u306e\u3082\u306e\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002NSCLC\u3084\u305d\u306e\u4ed6\u306e\u9069\u5fdc\u75c7\u3067\u306f\u3001\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u306f\u4e00\u90e8\u306e\u60a3\u8005\u69d8\u306b\u304a\u3044\u3066\u751f\u5b58\u671f\u9593\u3092\u6709\u610f\u306b\u5ef6\u9577\u3057\u307e\u3059\u3002 <strong>\u6cbb\u7642\u52b9\u679c\u306f\u60a3\u8005\u69d8\u3054\u3068\u306b\u5927\u304d\u304f\u7570\u306a\u308a\u307e\u3059<\/strong> \u816b\u760d\u306e\u7a2e\u985e\u3001PD-L1\u767a\u73fe\u3001MSI\/TMB\u30b9\u30c6\u30fc\u30bf\u30b9\u3001\u524d\u6cbb\u7642\u6b74\u3001\u5168\u8eab\u72b6\u614b\u3001\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u304c\u5358\u5264\u7642\u6cd5\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u308b\u304b\u4f75\u7528\u7642\u6cd5\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u308b\u304b\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002\u3054\u81ea\u8eab\u306e\u816b\u760d\u306b\u7279\u7570\u7684\u306a\u4e88\u60f3\u3055\u308c\u308b\u6cbb\u7642\u52b9\u679c\u306b\u3064\u3044\u3066\u306f\u3001\u62c5\u5f53\u306e\u816b\u760d\u5c02\u9580\u533b\u3068\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u30ad\u30a4\u30c8\u30eb\u30fc\u30c0\u306e\u52b9\u679c\u306f\u3044\u3064\u73fe\u308c\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u753b\u50cf\u4e0a\u306e\u52b9\u679c\u306f\u901a\u5e38\u3001\u6700\u521d\u306b\u6e2c\u5b9a\u53ef\u80fd\u3068\u306a\u308b\u306e\u306f <strong>9\uff5e12\u9031\u9593<\/strong> \uff083\uff5e4\u30b5\u30a4\u30af\u30eb\u5f8c\uff09\u3002\u4e00\u90e8\u306e\u60a3\u8005\u3067\u306f <strong>\u507d\u9032\u884c<\/strong> \u2014 \u521d\u56de\u753b\u50cf\u691c\u67fb\u3067\u306e\u4e00\u898b\u3057\u305f\u62e1\u5927\u306f\u3001\u816b\u760d\u3078\u306e\u514d\u75ab\u7d30\u80de\u6d78\u6f64\u306b\u3088\u308b\u3082\u306e\u3067\u3001\u305d\u306e\u5f8c\u306b\u771f\u306e\u6cbb\u7642\u53cd\u5fdc\u304c\u7d9a\u304d\u307e\u3059\u3002\u521d\u671f\u753b\u50cf\u3067\u6cbb\u7642\u5931\u6557\u3068\u5224\u65ad\u3059\u308b\u524d\u306b\u3001\u5c02\u9580\u533b\u306e\u5224\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">Keytruda\u6295\u4e0e\u4e2d\u306b\u751f\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u3044\u3044\u3048 \u2014 \u751f\u30ef\u30af\u30c1\u30f3\uff08MMR\u3001\u9ec4\u71b1\u75c5\u3001BCG\u3001\u7d4c\u53e3\u30dd\u30ea\u30aa\u3001\u6c34\u75d8\uff09\u306fKeytruda\u7642\u6cd5\u4e2d\u304a\u3088\u3073\u6700\u7d42\u6295\u4e0e\u304b\u3089\u5c11\u306a\u304f\u3068\u30826\u30f6\u6708\u9593\u306f\u7981\u5fcc\u3067\u3059\u3002\u4e0d\u6d3b\u5316\u30ef\u30af\u30c1\u30f3\uff08\u5e741\u56de\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3001\u80ba\u708e\u7403\u83cc\u3001COVID-19\u3001B\u578b\u809d\u708e\uff09\u306f\u5b89\u5168\u3067\u3042\u308b\u3060\u3051\u3067\u306a\u304f\u63a8\u5968\u3055\u308c\u307e\u3059 \u2014 \u304c\u3093\u60a3\u8005\u306f\u611f\u67d3\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u305f\u3081\u3001\u7a4d\u6975\u7684\u306b\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3092\u884c\u3046\u3079\u304d\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">Keytruda\u6295\u4e0e\u4e2d\u306b\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u670d\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n<p>irAE\uff08\u514d\u75ab\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff09\u7ba1\u7406\u306e\u305f\u3081\u306e\u77ed\u671f\u30b9\u30c6\u30ed\u30a4\u30c9\u6295\u4e0e\u306f\u9069\u5207\u304b\u3064\u5fc5\u8981\u3067\u3059\u3002 <strong>\u6162\u6027\u7684\u306a\u9ad8\u7528\u91cf\u30b9\u30c6\u30ed\u30a4\u30c9<\/strong> \uff08\u30d7\u30ec\u30c9\u30cb\u30be\u30f3\u63db\u7b9710 mg\/\u65e5\u8d85\u3092\u9577\u671f\u9593\uff09\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u3067\u6295\u4e0e\u3055\u308c\u3066\u3044\u308b\u3068\u3001Keytruda\u304c\u5897\u5f37\u3057\u3088\u3046\u3068\u8a2d\u8a08\u3055\u308c\u305f\u514d\u75ab\u5fdc\u7b54\u3092\u6291\u5236\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059 \u2014 \u816b\u760d\u533b\u306fKeytruda\u958b\u59cb\u524d\u306b\u3053\u308c\u3089\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u6e1b\u91cf\u3057\u3088\u3046\u3068\u8a66\u307f\u307e\u3059\u3002\u3082\u3057\u4ed6\u306e\u9069\u5fdc\u75c7\uff08\u5598\u606f\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3001\u79fb\u690d\uff09\u3067\u30b9\u30c6\u30ed\u30a4\u30c9\u304c\u5fc5\u8981\u306a\u5834\u5408\u306f\u3001\u816b\u760d\u533b\u3068\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3 class=\"wp-block-heading\">Keytruda\u306f\u598a\u5a20\u4e2d\u306b\u5b89\u5168\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u3044\u3044\u3048 \u2014 \u7d76\u5bfe\u7981\u5fcc\u3067\u3059\u3002\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u80ce\u76e4\u3092\u901a\u904e\u3057\u3001\u80ce\u5150\u306e\u514d\u75ab\u5bdb\u5bb9\u3092\u7834\u58ca\u3057\u3001\u91cd\u7be4\u306a\u7d50\u679c\uff08\u6b7b\u7523\u3001\u80ce\u5150\u81ea\u5df1\u514d\u75ab\u75be\u60a3\uff09\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u4fe1\u983c\u3067\u304d\u308b\u907f\u598a\u304c\u6cbb\u7642\u671f\u9593\u4e2d\u304a\u3088\u3073\u5c11\u306a\u304f\u3068\u3082 <strong>\u6700\u7d42\u6295\u4e0e\u304b\u30894\u30f6\u6708\u9593<\/strong>. \u3002\u6cbb\u7642\u4e2d\u304a\u3088\u3073\u305d\u306e\u5f8c4\u30f6\u6708\u9593\u306f\u6388\u4e73\u3092\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u306a\u305cKeytruda\u306f\u3053\u308c\u307b\u3069\u9ad8\u4fa1\u306a\u306e\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306f\u4e16\u754c\u7684\u306b\u6700\u3082\u9ad8\u4fa1\u306a\u304c\u3093\u6cbb\u7642\u85ac\u306e\u4e00\u3064\u3067\u3059 \u2014 \u5148\u767a\u54c1\u4fa1\u683c\u3067200 mg\u306e\u5358\u56de\u6295\u4e0e\u306f\u3001\u5272\u5f15\u524d\u3067\u9ad8\u6240\u5f97\u5e02\u5834\u3067\u306f1\u4e07\uff5e1\u4e074\u5343\u7c73\u30c9\u30eb\u304b\u304b\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u7406\u7531\uff1a\u8907\u96d1\u306a\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u88fd\u9020\u30012028\u5e74\u307e\u3067\u306e\u5148\u767a\u54c1\u7279\u8a31\u72ec\u5360\u3001\u9ad8\u3044\u7814\u7a76\u958b\u767a\u8cbb\u56de\u53ce\u3001\u30d7\u30ec\u30df\u30a2\u30e0\u4fa1\u683c\u3002\u60a3\u8005\u652f\u63f4\u30d7\u30ed\u30b0\u30e9\u30e0\uff08\u7c73\u56fd\u306eMerck's ACT\u30d7\u30ed\u30b0\u30e9\u30e0\u3001\u591a\u304f\u306e\u56fd\u3067\u306e\u6148\u5584\u30d7\u30ed\u30b0\u30e9\u30e0\uff09\u3001\u5229\u7528\u53ef\u80fd\u306a\u5834\u5408\u306e\u539f\u7523\u56fd\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u3001\u4e00\u90e8\u306e\u5e02\u5834\u3067\u767b\u5834\u3057\u3066\u3044\u308b\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6\u306e\u30d0\u30a4\u30aa\u30b7\u30df\u30e9\u30fc\u304c\u3001\u8cbb\u7528\u3092\u5927\u5e45\u306b\u524a\u6e1b\u3057\u307e\u3059\u3002\u7d4c\u6e08\u7684\u652f\u63f4\u306b\u3064\u3044\u3066\u306f\u3001\u816b\u760d\u30bd\u30fc\u30b7\u30e3\u30eb\u30ef\u30fc\u30ab\u30fc\u307e\u305f\u306f\u85ac\u5c40\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3 class=\"wp-block-heading\">Keytruda\u306e\u6295\u4e0e\u671f\u9593\u306f\u3069\u306e\u304f\u3089\u3044\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u9069\u5fdc\u75c7\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002 <strong>\u88dc\u52a9\u7642\u6cd5<\/strong> \uff08\u30e1\u30e9\u30ce\u30fc\u30de\u3001\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\u306a\u3069\u306b\u304a\u3051\u308b\u6839\u6cbb\u7684\u624b\u8853\u5f8c\uff09\uff1a\u901a\u5e381\u5e74\u9593\uff08Q3W\u306717\u30b5\u30a4\u30af\u30eb\u3001\u307e\u305f\u306fQ6W\u30679\u30b5\u30a4\u30af\u30eb\uff09\u3002 <strong>\u8ee2\u79fb\u6027\u75be\u60a3<\/strong>\uff1a\u75be\u60a3\u9032\u884c\u3001\u8a31\u5bb9\u3067\u304d\u306a\u3044\u6bd2\u6027\u3001\u307e\u305f\u306f\u6301\u7d9a\u7684\u306a\u5b8c\u5168\u594f\u52b9\u304c\u5f97\u3089\u308c\u305f\u60a3\u8005\u306b\u304a\u3051\u308b2\u5e74\u9593\u306e\u6cbb\u7642\u5b8c\u4e86\u307e\u3067\u3002\u5f53\u521d\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u6295\u4e0e\u671f\u9593\u306f2\u5e74\u9593\u306b\u5236\u9650\u3055\u308c\u3066\u304a\u308a\u30012\u5e74\u3067\u4e2d\u6b62\u3057\u305f\u5f8c\u306e\u594f\u52b9\u6301\u7d9a\u6027\u306f\u30e1\u30e9\u30ce\u30fc\u30de\u304a\u3088\u3073\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\u3067\u5b89\u5fc3\u3067\u304d\u308b\u7d50\u679c\u304c\u5f97\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4ed6\u306e\u9069\u5fdc\u75c7\u3067\u306f\u5341\u5206\u306b\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n<p><!-- medsbase-why-order --><\/p>\n<h3>MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n<p>\u3059\u3079\u3066\u306e\u30d0\u30c3\u30c1\u306f\u3001\uff5e\u304b\u3089\u8abf\u9054\u3055\u308c\u3066\u3044\u307e\u3059 <strong>WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4f9b\u7d66\u3055\u308c<\/strong>. \u3054\u6ce8\u6587\u306f\u3001\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305\u3067\u3001\u63d0\u643a\u767a\u9001\u30d1\u30fc\u30c8\u30ca\u30fc\u3088\u308a\u767a\u9001\u3055\u308c\u3001\u5f53\u5e97\u306e <a href=\"\/ja\/medsbase-re-shipment-assurance-policy\/\">\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/a>: 20\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u8377\u7269\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u3001\u7406\u7531\u3092\u554f\u308f\u305a\u7121\u6599\u3067\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u95a2\u9023\u3059\u308b\u6297\u304c\u3093\u5264<\/h3>\n<p>\u672c\u88fd\u54c1\u3068\u5408\u308f\u305b\u3066\u53d6\u308a\u6271\u3063\u3066\u3044\u308b\u305d\u306e\u4ed6\u306e\u304c\u3093\u6cbb\u7642\u85ac\uff1a<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ja\/votrient\/\">Votrient\uff08\u30d1\u30be\u30d1\u30cb\u30d6 200\/400 mg\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/imatib\/\">Imatib\uff08\u30a4\u30de\u30c1\u30cb\u30d6 100mg\/400mg\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/veenat\/\">Veenat\uff08\u30a4\u30de\u30c1\u30cb\u30d6 100mg\/400mg\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/tamilong\/\">Tamilong\uff08\u30bf\u30e2\u30ad\u30b7\u30d5\u30a7\u30f3 10\/20 mg\uff09<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/xtane\/\">Xtane\uff08\u30a8\u30ad\u30bb\u30e1\u30b9\u30bf\u30f3 25 mg\uff09<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 PD-1\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264<br \/>\n\u2705 15\u7a2e\u985e\u4ee5\u4e0a\u306e\u304c\u3093\u9069\u5fdc\u75c7\uff08\u30e1\u30e9\u30ce\u30fc\u30de\u3001\u975e\u5c0f\u7d30\u80de\u80ba\u304c\u3093\u3001MSI-H\/dMMR\u816b\u760d\u975e\u4f9d\u5b58\u6027\u3001\u982d\u9838\u90e8\u6241\u5e73\u4e0a\u76ae\u304c\u3093\u3001\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u3001\u5c3f\u8def\u4e0a\u76ae\u304c\u3093\u3001\u814e\u7d30\u80de\u304c\u3093\u3001\u30c8\u30ea\u30d7\u30eb\u30cd\u30ac\u30c6\u30a3\u30d6\u4e73\u304c\u3093\u3001\u5b50\u5bae\u5185\u819c\u304c\u3093\u306a\u3069\uff09<br \/>\n\u2705 200 mg 3\u9031\u9593\u3054\u3068\u307e\u305f\u306f400 mg 6\u9031\u9593\u3054\u3068\u306e\u70b9\u6ef4\u9759\u6ce8<br \/>\n\u2705 \u75c5\u9662\u307e\u305f\u306f\u816b\u760d\u79d1\u30c7\u30a4\u30e6\u30cb\u30c3\u30c8\u3067\u306e\u307f\u6295\u4e0e<br \/>\n\u2705 \u5c02\u9580\u816b\u760d\u533b\u306e\u76e3\u7763\u304c\u5fc5\u9808<\/p>\n<p>Keytruda\u306f\u30da\u30e0\u30d6\u30ed\u30ea\u30ba\u30de\u30d6100 mg\/4 mL\u3092\u542b\u6709\u3057\u307e\u3059\uff08Merck\/MSD\uff09\u3002PD-1\u3092\u963b\u5bb3\u3057\u3001\u514d\u75ab\u7cfb\u306e\u304c\u3093\u7d30\u80de\u8a8d\u8b58\u3092\u89e3\u653e\u3059\u308b\u30d2\u30c8\u5316\u30e2\u30ce\u30af\u30ed\u30fc\u30ca\u30eb\u6297\u4f53\u3067\u3059\u3002\u958b\u59cb\u524d\u306b\u306f\u5c02\u9580\u306e\u816b\u760d\u533b\u306b\u3088\u308b\u7ba1\u7406\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u75c5\u671f\u5206\u985e\u3001\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\uff08PD-L1\u3001MSI\/dMMR\uff09\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>","protected":false},"featured_media":53354,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3595,3141,3223],"product_tag":[],"class_list":{"0":"post-53353","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-cancer-medication","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","10":"first","11":"instock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product\/53353","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/comments?post=53353"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/media\/53354"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/media?parent=53353"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_brand?post=53353"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_cat?post=53353"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_tag?post=53353"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}