{"id":53698,"date":"2023-09-20T09:49:34","date_gmt":"2023-09-20T09:49:34","guid":{"rendered":"https:\/\/medsname.com\/vorier\/"},"modified":"2026-04-30T10:25:10","modified_gmt":"2026-04-30T10:25:10","slug":"vorier","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/vorier\/","title":{"rendered":"Vorier"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:14px 20px;margin:18px 0;border-radius:6px;\">\n<h3 style=\"margin-top:0;\">\ud83d\udca1 \u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc<\/h3>\n<p style=\"margin-bottom:0;\">Vorier \u306f\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb 200 mg \u7d4c\u53e3\u9320 \u2014 \u7b2c2\u4e16\u4ee3\u30c8\u30ea\u30a2\u30be\u30fc\u30eb\u7cfb\u6297\u771f\u83cc\u85ac\u3067\u3042\u308a\u3001 <strong>\u4fb5\u8972\u6027\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u75c7\u306e\u7b2c\u4e00\u9078\u629e\u6cbb\u7642\u3067\u3059\u3002<\/strong>. \u3002\u307e\u305f\u3001\u30ab\u30f3\u30b8\u30c0\uff08\u4e00\u90e8\u306e\u30d5\u30eb\u30b3\u30ca\u30be\u30fc\u30eb\u8010\u6027\u682a\u3092\u542b\u3080\uff09\u3001Scedosporium\u3001Fusarium\u306b\u3082\u6709\u52b9\u3067\u3059\u3002\u5c02\u9580\u75c5\u9662\u3067\u958b\u59cb\u3055\u308c\u308b\u85ac\u5264\u3067\u3042\u308a\u3001TDM\uff08\u30c8\u30e9\u30d5\u50241\uff5e5.5 mg\/L\uff09\u304c\u5fc5\u8981\u3067\u3001\u5fc5\u9808\u306e\u773c\u79d1\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u691c\u67fb\uff08\u8996\u899a\u969c\u5bb3\u304c\u3088\u304f\u307f\u3089\u308c\u308b\uff09\u3068\u983b\u7e41\u306a\u809d\u6a5f\u80fd\u691c\u67fb\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002\u975e\u5e38\u306b\u8907\u96d1\u306a\u85ac\u7269\u52d5\u614b\uff1a\u975e\u7dda\u5f62\uff08CYP2C19\u907a\u4f1d\u5b50\u591a\u578b\uff09\u3001\u5f37\u529b\u306aCYP3A4\u963b\u5bb3\u4f5c\u7528\u3001\u5149\u7dda\u904e\u654f\u75c7\u2192\u9577\u671f\u4f7f\u7528\u3067\u76ae\u819a\u304c\u3093\u30ea\u30b9\u30af\u3002<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f5f5f5;border:1px solid #e1e1e1;padding:18px 22px;margin:24px 0;border-radius:8px;display:flex;flex-wrap:wrap;justify-content:space-around;gap:16px;align-items:center;font-size:0.95em;\">\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udfed<br \/><strong>WHO-GMP<\/strong><br \/>\u8a8d\u8a3c\u88fd\u9020\u5143<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u3001\u5f53\u5e97\u306e <a href=\"https:\/\/medsbase.com\/ja\/medsbase-re-shipment-assurance-policy\/\"><strong>\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u5546\u54c1\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u306f\u3001\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<h3>MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n<p>\u5f53\u5e97\u306e\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306f\u3001WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4ed5\u5165\u308c\u3001\u5168\u4e16\u754c\u3078\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u7121\u5730\u306e\u68b1\u5305\u3067\u767a\u9001\u3055\u308c\u307e\u3059\u3002\u914d\u9001\u7bb1\u306e\u5916\u5074\u306b\u306f\u533b\u85ac\u54c1\u540d\u306f\u4e00\u5207\u8a18\u8f09\u3055\u308c\u307e\u305b\u3093\u3002\u30ab\u30fc\u30c9\u6c7a\u6e08\u306f\u3001\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u3092\u7d4c\u7531\u3057\u3066\u51e6\u7406\u3055\u308c\uff08\u660e\u7d30\u66f8\u306e\u8868\u793a\u306b\u306f\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u306e\u307f\u304c\u8a18\u8f09\u3055\u308c\u3001\u300cMedsBase\u300d\u3084\u533b\u85ac\u54c1\u540d\u304c\u8868\u793a\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\uff09\u3001\u6697\u53f7\u8cc7\u7523\u3084SEPA\u9280\u884c\u632f\u8fbc\u3082\u3054\u5229\u7528\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306b\u306f\u3001\u5f53\u5e97\u306e\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc\u304c\u9069\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83d\udce6<br \/><strong>\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305<\/strong><br \/>\u7121\u5730\u306e\u5c01\u7b52<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\ud83c\udf0d<br \/><strong>\u5168\u4e16\u754c\u914d\u9001<\/strong><br \/>\u307b\u3068\u3093\u3069\u306e\u56fd\u3078<\/div>\n<div style=\"text-align:center;flex:1;min-width:140px;\">\u2b50<br \/><strong>1,400\u4eba\u4ee5\u4e0a\u306e\u304a\u5ba2\u69d8<\/strong><br \/><a href=\"https:\/\/medsbase.com\/ja\/reviews\/\">\u30ec\u30d3\u30e5\u30fc\u3092\u8aad\u3080<\/a><\/div>\n<\/div>\n<h2>\ud83d\udd12 \u306a\u305c MedsBase \u3067 Vorier \u3092\u6ce8\u6587\u3059\u308b\u306e\u3067\u3059\u304b\uff1f<\/h2>\n<ul>\n<li><strong>WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4f9b\u7d66\u3055\u308c<\/strong> \u2014 \u898f\u5236\u3055\u308c\u305f\u65bd\u8a2d\u304b\u3089\u8abf\u9054\u3055\u308c\u305f\u3001\u30ed\u30c3\u30c8\u756a\u53f7\u3068\u4f7f\u7528\u671f\u9650\u5165\u308a\u306e\u6700\u7d42\u5305\u88c5\u54c1\u3067\u3059\u3002<\/li>\n<li><strong>\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305<\/strong> \u2014 \u7121\u5730\u306e\u5c01\u7b52\u3067\u3001\u5916\u5074\u306b\u533b\u85ac\u54c1\u540d\u306f\u8a18\u8f09\u3055\u308c\u307e\u305b\u3093\u3002<\/li>\n<li><strong>\u5168\u4e16\u754c\u914d\u9001<\/strong> \u307b\u3068\u3093\u3069\u306e\u56fd\u3078\u3001 <a href=\"https:\/\/medsbase.com\/ja\/medsbase-re-shipment-assurance-policy\/\">\u518d\u767a\u9001\u4fdd\u8a3c<\/a>.<\/li>\n<li><strong>\u30ed\u30a4\u30e4\u30eb\u30c6\u30a3\u30dd\u30a4\u30f3\u30c8<\/strong> \u2014 \u3054\u5229\u7528\u984d1\u30c9\u30eb\u306b\u3064\u304d1\u30dd\u30a4\u30f3\u30c8\uff08\u30da\u30d7\u30c1\u30c9\uff0f\u914d\u9001\u6599\u3092\u9664\u304f\uff09\u3002100\u30dd\u30a4\u30f3\u30c8\u3067\u6b21\u56de\u6ce8\u6587\u6642\u306b5\u30c9\u30eb\u5272\u5f15\u3002<\/li>\n<\/ul>\n<h2 id=\"uses\">\u7528\u9014\u3068\u9069\u5fdc\u75c7<\/h2>\n<p>Vorier\uff08\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb 200 mg\u3001Glenmark\uff09\u306f\u5c02\u9580\u7684\u306a\u6297\u771f\u83cc\u85ac\u3067\u3042\u308a\u3001\u4fb5\u8972\u6027\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u75c7\u306b\u5bfe\u3059\u308b\u7b2c\u4e00\u9078\u629e\u85ac\uff08Herbrecht 2002\u5e74NEJM\u8a66\u9a13\u3067\u78ba\u7acb\uff09\u3067\u3042\u308a\u3001\u4fb5\u8972\u6027\u30ab\u30f3\u30b8\u30c0\u75c7\u3001Scedosporium\u304a\u3088\u3073Fusarium\u611f\u67d3\u75c7\u3001\u30d5\u30eb\u30b3\u30ca\u30be\u30fc\u30eb\u4e0d\u5fdc\u6027\u306e\u98df\u9053\u30ab\u30f3\u30b8\u30c0\u75c7\u3001\u9078\u629e\u3055\u308c\u305f\u75c7\u4f8b\u306b\u304a\u3051\u308b\u767a\u71b1\u6027\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7\u306b\u5bfe\u3059\u308b\u9078\u629e\u80a2\u3067\u3082\u3042\u308a\u307e\u3059\u3002 <strong>\u3053\u308c\u306f\u3001\u81a3\u30ab\u30f3\u30b8\u30c0\u75c7\u3001\u53e3\u8154\u30ab\u30f3\u30b8\u30c0\u75c7\u3001\u722a\u771f\u83cc\u75c7\u306e\u7b2c\u4e00\u9078\u629e\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong> \u2500\u305d\u308c\u3089\u306b\u306f\u30d5\u30eb\u30b3\u30ca\u30be\u30fc\u30eb\u307e\u305f\u306f\u30c6\u30eb\u30d3\u30ca\u30d5\u30a3\u30f3\u3092\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u9069\u5fdc\u75c7<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u6a19\u6e96\u7684\u306a\u7528\u6cd5<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u4fb5\u8972\u6027\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u75c7<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u9759\u6ce8\u8ca0\u8377\u6295\u4e0e\uff1a6 mg\uff0fkg\u309212\u6642\u9593\u3054\u3068\u306b24\u6642\u9593\u9759\u6ce8\u3001\u305d\u306e\u5f8c4 mg\uff0fkg\u309212\u6642\u9593\u3054\u3068\u306b\u9759\u6ce8\u3002\u307e\u305f\u306f\u7d4c\u53e3\u3067200 mg\u309212\u6642\u9593\u3054\u3068\uff08\u4f53\u91cd40 kg\u4ee5\u4e0a\uff09\uff0f100 mg\u309212\u6642\u9593\u3054\u3068\uff0840 kg\u672a\u6e80\uff09<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30ab\u30f3\u30b8\u30c0\u8840\u75c7\uff08\u975e\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7\uff09<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u540c\u4e00\u7528\u91cf \u2014 \u6700\u521d\u306e\u8840\u6db2\u57f9\u990a\u9670\u6027\u5316\u5f8c\u3001\u6700\u4f4e14\u65e5\u9593<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u98df\u9053\u30ab\u30f3\u30b8\u30c0\u75c7\uff08\u30d5\u30eb\u30b3\u30ca\u30be\u30fc\u30eb\u62b5\u6297\u6027\uff09<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">200 mg\u309212\u6642\u9593\u3054\u3068\u306b14\uff5e21\u65e5\u9593<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30b9\u30b1\u30c9\u30b9\u30dd\u30ea\u30a6\u30e0\uff0f\u30d5\u30b6\u30ea\u30a6\u30e0\u611f\u67d3\u75c7<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">200 mg\u309212\u6642\u9593\u3054\u3068\u306b\u3001\u6cbb\u7642\u53cd\u5fdc\u306b\u5fdc\u3058\u3066\u6295\u4e0e\u671f\u9593\u3092\u8a2d\u5b9a<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u767a\u71b1\u6027\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7\u306b\u304a\u3051\u308b\u7d4c\u9a13\u7684\u6cbb\u7642<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">200 mg\u309212\u6642\u9593\u3054\u3068\u306b<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"how-to-take\">\u670d\u7528\u65b9\u6cd5<\/h2>\n<ul>\n<li>\u98df\u524d1\u6642\u9593\u307e\u305f\u306f\u98df\u5f8c1\u6642\u9593\u306b\u670d\u7528\u3057\u3066\u304f\u3060\u3055\u3044 \u2014 \u98df\u4e8b\u306b\u3088\u308a\u5438\u53ce\u304c\u7d0422%\u4f4e\u4e0b\u3057\u307e\u3059\u3002<\/li>\n<li>\u30b3\u30c3\u30d7\u4e00\u676f\u306e\u6c34\u3067\u4e38\u3054\u3068\u304a\u98f2\u307f\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u8ca0\u8377\u6295\u4e0e\u306f\u91cd\u8981\u3067\u3059 \u2014 \u3053\u308c\u3092\u884c\u308f\u306a\u3044\u5834\u5408\u3001\u5b9a\u5e38\u72b6\u614b\u306b\u9054\u3059\u308b\u307e\u3067\u306b5\uff5e7\u65e5\u304b\u304b\u308a\u307e\u3059\u3002<\/li>\n<li>\u6cbb\u7642\u85ac\u7269\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\uff08\u30c8\u30e9\u30d5\u50241\uff5e5.5 mg\uff0fL\uff09\u3092\u6295\u4e0e\u958b\u59cb5\uff5e7\u65e5\u5f8c\u304a\u3088\u3073\u7528\u91cf\u5909\u66f4\u5f8c\u306b\u5b9f\u65bd\u3057\u307e\u3059\u3002<\/li>\n<\/ul>\n<h2 id=\"mechanism\">\u3069\u306e\u3088\u3046\u306a\u4ed5\u7d44\u307f\u3067\u3059\u304b\uff1f<\/h2>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306f\u30d5\u30eb\u30b3\u30ca\u30be\u30fc\u30eb\u3088\u308a\u3082\u9ad8\u3044\u89aa\u548c\u6027\u3067\u771f\u83cc\u306eCYP51\u3092\u963b\u5bb3\u3057\u3001\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u3084\u307b\u3068\u3093\u3069\u306e\u975e\u30a2\u30eb\u30d3\u30ab\u30f3\u30b9\u30ab\u30f3\u30b8\u30c0\u306b\u307e\u3067\u6297\u83cc\u30b9\u30da\u30af\u30c8\u30eb\u3092\u62e1\u5927\u3057\u307e\u3059\u3002\u6210\u4eba\u3067\u306f\u85ac\u7269\u52d5\u614b\u304c\u975e\u7dda\u5f62\u3067\u3042\u308a\u3001\u5c11\u91cf\u306e\u7528\u91cf\u5909\u66f4\u304c\u5927\u304d\u306a\u6fc3\u5ea6\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002CYP2C19\u907a\u4f1d\u5b50\u591a\u578b\uff1a\u4f4e\u4ee3\u8b1d\u7fa4\uff08\u6771\u30a2\u30b8\u30a2\u4eba\u306e15%\u3001\u767d\u4eba\u3067\u306f3%\uff09\u3067\u306f\u8840\u6f3f\u4e2d\u6fc3\u5ea6\u304c4\u500d\u9ad8\u304f\u306a\u308a\u3001\u8d85\u9ad8\u901f\u4ee3\u8b1d\u7fa4\u3067\u306f\u6cbb\u7642\u57df\u306b\u9054\u3057\u306a\u3044\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002 <strong>\u3053\u308c\u304c\u3001TDM\u304c\u5fc5\u9808\u3067\u3042\u308b\u7406\u7531\u3067\u3059\u3002<\/strong><\/p>\n<h2 id=\"side-effects\">\u526f\u4f5c\u7528\u3068\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u983b\u5ea6<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u526f\u4f5c\u7528<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u975e\u5e38\u306b\u591a\u3044<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\"><strong>\u8996\u899a\u969c\u5bb3<\/strong> \u2014 \u304b\u3059\u307f\u76ee\u3001\u5149\u8996\u75c7\u3001\u8272\u899a\u7570\u5e38\uff08\u7d0430\uff05\u3001\u7279\u306b\u521d\u9031\u306b\u767a\u73fe\u3001\u53ef\u9006\u7684\uff09<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u4e00\u822c\u7684<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u767a\u75b9\u3001\u60aa\u5fc3\u3001\u5614\u5410\u3001\u8179\u75db\u3001\u4e0b\u75e2\u3001\u672b\u68a2\u6027\u6d6e\u816b\u3001\u767a\u71b1\u3001\u809d\u6a5f\u80fd\u691c\u67fb\u5024\u4e0a\u6607<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u307e\u308c\u306b\u3042\u308b<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u5149\u7dda\u904e\u654f\u75c7\uff0f\u5149\u6bd2\u6027\u3001\u5e7b\u899a\u3001\u932f\u4e71\u3001\u4f4e\u30ab\u30ea\u30a6\u30e0\u8840\u75c7<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u307e\u308c\u3060\u304c\u91cd\u7be4<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u809d\u6bd2\u6027\uff08\u81f4\u6b7b\u7684\u809d\u708e\u3092\u542b\u3080\uff09\u3001QT\u5ef6\u9577\uff0f\u30c8\u30eb\u30b5\u30fc\u30c9\u30fb\u30c9\u30fb\u30dd\u30a2\u30f3\u30c8\u3001\u30b9\u30c6\u30a3\u30fc\u30d6\u30f3\u30b9\u30fb\u30b8\u30e7\u30f3\u30bd\u30f3\u75c7\u5019\u7fa4\uff0f\u4e2d\u6bd2\u6027\u8868\u76ae\u58ca\u6b7b\u878d\u89e3\u75c7\u3001\u9aa8\u819c\u708e\uff08\u9577\u671f\u6295\u4e0e\u6642\u2014\u30d5\u30c3\u7d20\u84c4\u7a4d\uff09\u3001\u6709\u68d8\u7d30\u80de\u764c\uff08\u9577\u671f\u306e\u5149\u7dda\u904e\u654f\u75c7\u306b\u3088\u308b\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 20px;margin:20px 0;border-radius:6px;\"><strong>\u76ae\u819a\u304c\u3093\u306b\u95a2\u3059\u308b\u8b66\u544a<\/strong><\/p>\n<div>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306f\u91cd\u5ea6\u306e\u5149\u7dda\u904e\u654f\u75c7\u3092\u8a98\u767a\u3057\u3001\u9577\u671f\u6cbb\u7642\uff08\u5927\u534a\u304c6\u304b\u6708\u8d85\u306e\u7d99\u7d9a\u4f7f\u7528\uff09\u3067\u306f\u6709\u68d8\u7d30\u80de\u764c\u3068\u306e\u95a2\u9023\u304c\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u3092\u9577\u671f\u670d\u7528\u3059\u308b\u60a3\u8005\u69d8\u306f\u3001SPF50\u4ee5\u4e0a\u306e\u5e83\u57df\u30b9\u30da\u30af\u30c8\u30e9\u30e0\u65e5\u713c\u3051\u6b62\u3081\u3092\u6bce\u65e5\u4f7f\u7528\u3057\u3001\u76f4\u5c04\u65e5\u5149\u3092\u907f\u3051\u3001\u5e74\u306b\u4e00\u5ea6\u306e\u76ae\u819a\u79d1\u691c\u8a3a\u3092\u53d7\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u65e5\u5149\u9732\u51fa\u90e8\u306b\u65b0\u305f\u306a\u76ae\u819a\u75c5\u5909\u304c\u751f\u3058\u305f\u5834\u5408\u306f\u3001\u76f4\u3061\u306b\u76ae\u819a\u79d1\u3092\u53d7\u8a3a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/div>\n<\/div>\n<h2 id=\"interactions\">\u85ac\u7269\u76f8\u4e92\u4f5c\u7528 \u2014 \u591a\u5c90\u306b\u308f\u305f\u308b<\/h2>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306fCYP2C19\u3001CYP2C9\u3001CYP3A4\u3067\u4ee3\u8b1d\u3055\u308c\u3001\u304b\u3064\u3053\u308c\u30893\u7a2e\u3059\u3079\u3066\u306e\u5f37\u529b\u306a\u963b\u5bb3\u5264\u3067\u3082\u3042\u308a\u307e\u3059\u3002\u4e3b\u306a\u6ce8\u610f\u70b9\uff1a<\/p>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:0.95em;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u85ac\u5264<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u52b9\u679c<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ccc;\">\u5bfe\u5fdc<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30ea\u30d5\u30a1\u30f3\u30d4\u30b7\u30f3\uff0f\u30ea\u30d5\u30a1\u30d6\u30c1\u30f3\uff0f\u30ab\u30eb\u30d0\u30de\u30bc\u30d4\u30f3\uff0f\u30d5\u30a7\u30ce\u30d0\u30eb\u30d3\u30bf\u30fc\u30eb<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u5f37\u529b\u306a\u8a98\u5c0e \u2192 \u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u304c\u691c\u51fa\u9650\u754c\u4ee5\u4e0b\u306b<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u7981\u5fcc<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30bb\u30f3\u30c8\u30fb\u30b8\u30e7\u30fc\u30f3\u30ba\u30fb\u30ef\u30fc\u30c8<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u540c\u69d8\u306e\u8a98\u5c0e\u4f5c\u7528<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u7981\u5fcc<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30b7\u30ed\u30ea\u30e0\u30b9<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">8\u500d\u306b\u4e0a\u6607 \u2014 \u91cd\u7be4\u306a\u6bd2\u6027<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u7981\u5fcc<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30d4\u30e2\u30b8\u30c9\uff0f\u30ad\u30cb\u30b8\u30f3\uff0f\u30c6\u30eb\u30d5\u30a7\u30ca\u30b8\u30f3\uff0f\u30b7\u30b5\u30d7\u30ea\u30c9<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">QT\u5ef6\u9577<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u7981\u5fcc<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u9ea6\u89d2\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u8840\u7ba1\u53ce\u7e2e \u2192 \u9ea6\u89d2\u4e2d\u6bd2<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u7981\u5fcc<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\uff0f\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">2\uff5e3\u500d\u306b\u4e0a\u6607<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u6e1b\u91cf\uff1b\u30c8\u30e9\u30d5\u5024\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30ef\u30eb\u30d5\u30a1\u30ea\u30f3<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">INR\u306f\u4e0a\u6607\u3059\u308b<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">INR\u3092\u53b3\u91cd\u306b\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30b9\u30bf\u30c1\u30f3\u7cfb\u85ac\u5264\uff08\u30b7\u30f3\u30d0\u30b9\u30bf\u30c1\u30f3\u3001\u30a2\u30c8\u30eb\u30d0\u30b9\u30bf\u30c1\u30f3\uff09<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u6a2a\u7d0b\u7b4b\u878d\u89e3\u75c7\u306e\u30ea\u30b9\u30af<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u4e2d\u6b62\u3059\u308b\u304b\u3001\u30d7\u30e9\u30d0\u30b9\u30bf\u30c1\u30f3\u306b\u5207\u308a\u66ff\u3048<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30d5\u30a7\u30cb\u30c8\u30a4\u30f3<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u53cc\u65b9\u5411\u6027 \u2014 \u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u6fc3\u5ea6\u304c\u4f4e\u4e0b\u3057\u3001\u30d5\u30a7\u30cb\u30c8\u30a4\u30f3\u6fc3\u5ea6\u304c\u4e0a\u6607<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u4f75\u7528\u56de\u907f\uff1b\u3084\u3080\u3092\u5f97\u305a\u4f7f\u7528\u3059\u308b\u5834\u5408\u306f\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u3092100%\u5897\u91cf\u3057\u3001\u30d5\u30a7\u30cb\u30c8\u30a4\u30f3\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb\uff0f\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">PPI\u6fc3\u5ea6\u304c\u4e0a\u6607\uff1b\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u3078\u306e\u5f71\u97ff\u306f\u8efd\u5ea6<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">PPI\u306e\u7528\u91cf\u3092\u534a\u6e1b<\/td>\n<\/tr>\n<tr style=\"background:#fff;\">\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30e1\u30b5\u30c9\u30f3\u3001\u30aa\u30d4\u30aa\u30a4\u30c9<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u4e2d\u67a2\u795e\u7d4c\u6291\u5236\u4f5c\u7528\u306e\u5897\u5f37<\/td>\n<td style=\"padding:8px;border:1px solid #ccc;\">\u30aa\u30d4\u30aa\u30a4\u30c9\u306e\u7528\u91cf\u3092\u6e1b\u91cf<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 id=\"monitoring\">\u5fc5\u9808\u306e\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/h2>\n<ul>\n<li><strong>\u6cbb\u7642\u85ac\u7269\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/strong> \u2014 \u30c8\u30e9\u30d5\u8840\u6f3f\u4e2d\u6fc3\u5ea6\u3092\u6295\u4e0e5\uff5e7\u65e5\u76ee\u304a\u3088\u3073\u7528\u91cf\u5909\u66f4\u306e\u305f\u3073\u306b\u6e2c\u5b9a\u3002\u76ee\u6a19\u5024\u306f1.0\uff5e5.5 mg\/L\uff08\u4fb5\u8972\u6027\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u75c7\u3067\u306f\u4e00\u90e8\u306e\u691c\u67fb\u6a5f\u95a2\u30672.0\uff5e5.5\uff09\u3002<\/li>\n<li><strong>\u809d\u6a5f\u80fd<\/strong> \u2014 \u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u3001\u305d\u306e\u5f8c2\uff5e4\u9031\u9593\u306f\u6bce\u9031\u3001\u4ee5\u964d\u306f\u6cbb\u7642\u4e2d\u306f\u6bce\u6708\u3002<\/li>\n<li><strong>\u8996\u6a5f\u80fd<\/strong> \u2014 28\u65e5\u3092\u8d85\u3048\u308b\u6cbb\u7642\u304c\u898b\u8fbc\u307e\u308c\u308b\u5834\u5408\u306f\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u6642\u306b\u773c\u79d1\u691c\u67fb\u3092\u5b9f\u65bd\u3002<\/li>\n<li><strong>\u814e\u6a5f\u80fd<\/strong> \u2014 \u9759\u6ce8\u88fd\u5264\u306f\u30b7\u30af\u30ed\u30c7\u30ad\u30b9\u30c8\u30ea\u30f3\u3092\u542b\u6709\u3002\u7d4c\u53e3\u5264\u306f\u554f\u984c\u306a\u3044\u304c\u3001CrCl 50\u672a\u6e80\u3067\u306f\u6709\u76ca\u6027\u304c\u30ea\u30b9\u30af\u3092\u660e\u3089\u304b\u306b\u4e0a\u56de\u308b\u5834\u5408\u3092\u9664\u304d\u56de\u907f\u3002<\/li>\n<li><strong>\u76ae\u819a\uff0f\u76ae\u819a\u79d1<\/strong> \u2014 \u9577\u671f\u6cbb\u7642\u4e2d\u306f\u5e741\u56de\u306e\u8a3a\u5bdf\u3092\u5b9f\u65bd\u3002<\/li>\n<\/ul>\n<h2 id=\"contraindications\">\u7981\u5fcc<\/h2>\n<ul>\n<li>\u30ea\u30d5\u30a1\u30f3\u30d4\u30b7\u30f3\u3001\u30ea\u30d5\u30a1\u30d6\u30c1\u30f3\u3001\u30ab\u30eb\u30d0\u30de\u30bc\u30d4\u30f3\u3001\u30d5\u30a7\u30ce\u30d0\u30eb\u30d3\u30bf\u30fc\u30eb\u3001\u30bb\u30f3\u30c8\u30b8\u30e7\u30fc\u30f3\u30ba\u30ef\u30fc\u30c8\u306e\u4f75\u7528\u3002<\/li>\n<li>\u30d4\u30e2\u30b8\u30c9\u3001\u30ad\u30cb\u30b8\u30f3\u3001\u30c6\u30eb\u30d5\u30a7\u30ca\u30b8\u30f3\u3001\u30b7\u30b5\u30d7\u30ea\u30c9\u3001\u9ea6\u89d2\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u3001\u30b7\u30ed\u30ea\u30e0\u30b9\u306e\u4f75\u7528\u3002<\/li>\n<li>\u598a\u5a20\uff08\u50ac\u5947\u5f62\u6027\uff09\u3002<\/li>\n<li>\u91cd\u5ea6\u306e\u809d\u6a5f\u80fd\u969c\u5bb3\u3002<\/li>\n<li>\u4ed6\u306e\u30a2\u30be\u30fc\u30eb\u7cfb\u85ac\u5264\u306b\u5bfe\u3059\u308b\u904e\u654f\u75c7\u3002<\/li>\n<\/ul>\n<h2 id=\"pregnancy\">\u598a\u5a20\u4e2d\u30fb\u6388\u4e73\u4e2d<\/h2>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306f\u52d5\u7269\u5b9f\u9a13\u3067\u50ac\u5947\u5f62\u6027\u304c\u8a8d\u3081\u3089\u308c\u3066\u304a\u308a\u3001\u751f\u547d\u3092\u8105\u304b\u3059\u5168\u8eab\u6027\u771f\u83cc\u75c7\u306e\u5834\u5408\u3092\u9664\u304d\u3001\u598a\u5a20\u4e2d\u306f\u7981\u5fcc\u3067\u3059\u3002\u52b9\u679c\u7684\u306a\u907f\u598a\u304c\u5fc5\u8981\u3067\u3059\u3002\u6bcd\u4e73\u4e2d\u3078\u306e\u79fb\u884c\u306f\u4e0d\u660e\u3067\u3042\u308a\u3001\u6388\u4e73\u4e2d\u306f\u4ee3\u66ff\u85ac\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002<\/p>\n<h2 id=\"faqs\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n<h3>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u3092\u670d\u7528\u3059\u308b\u3068\u5149\u306e\u30d5\u30e9\u30c3\u30b7\u30e5\u304c\u898b\u3048\u308b\u306e\u3067\u3059\u304c\u3001\u3053\u308c\u306f\u6b63\u5e38\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u306f\u3044 \u2014 \u8996\u899a\u969c\u5bb3\uff08\u5149\u8996\u75c7\u3001\u304b\u3059\u307f\u76ee\u3001\u8272\u899a\u5909\u5316\uff09\u306f\u60a3\u8005\u306e\u7d0430%\u306b\u767a\u751f\u3057\u3001\u901a\u5e38\u306f\u670d\u7528\u5f8c2\u6642\u9593\u4ee5\u5185\u306b\u73fe\u308c\u3001\u6cbb\u7642\u7d99\u7d9a\u4e2d\u3067\u3082\u6570\u65e5\u304b\u3089\u6570\u9031\u9593\u3067\u6d88\u5931\u3057\u307e\u3059\u3002\u5f71\u97ff\u304c\u306f\u3063\u304d\u308a\u3059\u308b\u307e\u3067\u306f\u591c\u9593\u306e\u904b\u8ee2\u3092\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002\u91cd\u5ea6\u307e\u305f\u306f\u6301\u7d9a\u3059\u308b\u5834\u5408\u306f\u3001TDM\uff08\u6cbb\u7642\u85ac\u7269\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\uff09\u3092\u4f9d\u983c\u3057\u3066\u304f\u3060\u3055\u3044 \u2014 \u30c8\u30e9\u30d5\u5024\u304c\u9ad8\u3044\u3068\u60aa\u5316\u3057\u307e\u3059\u3002<\/p>\n<h3>\u306a\u305c\u79c1\u306eCYP2C19\u306e\u72b6\u614b\u304c\u305d\u3093\u306a\u306b\u5fc3\u914d\u3055\u308c\u308b\u306e\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306fCYP2C19\u306b\u3088\u3063\u3066\u4ee3\u8b1d\u3055\u308c\u307e\u3059\u3002\u4ee3\u8b1d\u4e0d\u826f\u7fa4\uff08\u6771\u30a2\u30b8\u30a2\u7cfb\u306e15%\u3001\u767d\u4eba\u7cfb\u306e3%\uff09\u3067\u306f\u3001\u6a19\u6e96\u7528\u91cf\u3067\u66dd\u9732\u91cf\u304c4\u500d\u306b\u4e0a\u6607\u3057\u3001\u6bd2\u6027\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002\u8d85\u9ad8\u901f\u4ee3\u8b1d\u7fa4\u3067\u306f\u6cbb\u7642\u6fc3\u5ea6\u306b\u9054\u305b\u305a\u3001\u6cbb\u7642\u5931\u6557\u3068\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u85ac\u7406\u907a\u4f1d\u5b66\u7684\u691c\u67fb\u3001\u307e\u305f\u306f\u5358\u306b5\uff5e7\u65e5\u76ee\u306eTDM\u3067\u3053\u306e\u554f\u984c\u306f\u89e3\u6c7a\u3057\u307e\u3059\u3002<\/p>\n<h3>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306e\u9759\u6ce8\u304b\u3089\u7d4c\u53e3\u306b\u5207\u308a\u66ff\u3048\u3089\u308c\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u306f\u3044 \u2014 \u60a3\u8005\u304c\u5b89\u5b9a\u3057\u3001\u7d4c\u53e3\u6295\u4e0e\u306b\u8010\u3048\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u308c\u3070\u53ef\u80fd\u3067\u3059\u3002\u6210\u4eba\u306b\u304a\u3051\u308b\u7d4c\u53e3\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u306f\u7d0496%\u3067\u3042\u308b\u305f\u3081\u3001\u7528\u91cf\u306f\u540c\u3058\u3067\u3059\uff08\u4f53\u91cd40kg\u4ee5\u4e0a\u306e\u6210\u4eba\u306e\u5834\u5408\u3001200mg\u309212\u6642\u9593\u3054\u3068\uff09\u3002<\/p>\n<h3>\u3069\u306e\u65e5\u713c\u3051\u6b62\u3081\u3092\u4f7f\u7528\u3059\u308c\u3070\u3088\u3044\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u6700\u4f4e\u3067\u3082\u30d6\u30ed\u30fc\u30c9\u30b9\u30da\u30af\u30c8\u30e9\u30e0\uff08\u7d2b\u5916\u7ddaA\u6ce2\u30fbB\u6ce2\u9632\u6b62\uff09\u306eSPF50+\u3092\u3001\u6bce\u65e5\u3001\u66c7\u308a\u306e\u65e5\u3067\u3082\u304a\u4f7f\u3044\u304f\u3060\u3055\u3044\u3002\u5c4b\u5916\u306b\u3044\u308b\u5834\u5408\u306f2\u6642\u9593\u3054\u3068\u306b\u5857\u308a\u76f4\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u9577\u6642\u9593\u306e\u9732\u51fa\u306b\u306f\u9577\u8896\u306eUV\u30ab\u30c3\u30c8\u8863\u985e\u3092\u7740\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u65e5\u713c\u3051\u30de\u30b7\u30f3\u306f\u5b8c\u5168\u306b\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3>\u300c\u9aa8\u819c\u708e\u300d\u3068\u300c\u30d5\u30c3\u5316\u7269\u6bd2\u6027\u300d\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306b\u306f\u30d5\u30c3\u5316\u7269\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u9577\u671f\u6cbb\u7642\uff08\u6570\u304b\u6708\uff09\u3067\u306f\u3001\u30a2\u30eb\u30ab\u30ea\u30db\u30b9\u30d5\u30a1\u30bf\u30fc\u30bc\u304a\u3088\u3073\u8840\u6e05\u30d5\u30c3\u5316\u7269\u6fc3\u5ea6\u306e\u4e0a\u6607\u3092\u4f34\u3046\u75db\u307f\u3092\u4f34\u3046\u9aa8\u819c\u708e\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u9aa8\u30b7\u30f3\u30c1\u30b0\u30e9\u30d5\u30a3\u30fc\u3067\u96c6\u7a4d\u304c\u898b\u3089\u308c\u307e\u3059\u3002\u6295\u4e0e\u3092\u4e2d\u6b62\u3059\u308b\u3068\u6539\u5584\u3057\u307e\u3059\u3002\u9577\u671f\u6cbb\u7642\u4e2d\u306b\u65b0\u305f\u306b\u539f\u56e0\u4e0d\u660e\u306e\u9aa8\u75db\u304c\u751f\u3058\u305f\u5834\u5408\u306f\u3001ALP\u3068\u8840\u6e05\u30d5\u30c3\u5316\u7269\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306fVfend\u3068\u540c\u3058\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u306f\u3044\u3001Vfend\u306f\u30d5\u30a1\u30a4\u30b6\u30fc\u306e\u5148\u767a\u30d6\u30e9\u30f3\u30c9\u3067\u3059\u3002Vorier\u306b\u306f\u540c\u3058\u6709\u52b9\u6210\u5206\u304c\u542b\u307e\u308c\u3066\u304a\u308a\u3001WHO-GMP\u8a8d\u8a3c\u306eGlenmark\u793e\u306b\u3088\u3063\u3066\u88fd\u9020\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u751f\u7269\u5b66\u7684\u306b\u540c\u7b49\u3067\u3059\u3002<\/p>\n<h3>\u306a\u305c\u79c1\u306e\u722a\u767d\u766c\u306e\u5c02\u9580\u533b\u306f\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u3092\u4f7f\u308f\u306a\u3044\u306e\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306f\u4fb5\u8972\u6027\u5168\u8eab\u771f\u83cc\u75c7\u306b\u9650\u5b9a\u3057\u3066\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\uff08\u4e00\u822c\u7684\u306a\u539f\u56e0\u3067\u3042\u308b\uff09\u76ae\u819a\u7cf8\u72b6\u83cc\u306b\u3088\u308b\u722a\u611f\u67d3\u75c7\u306b\u306f\u3001\u30c6\u30eb\u30d3\u30ca\u30d5\u30a3\u30f3250mg\/\u65e5\u00d712\u9031\u9593\u304c\u7b2c\u4e00\u9078\u629e\u3067\u3059 \u2014 \u6cbb\u7652\u7387\u304c\u9ad8\u304f\u3001\u76f8\u4e92\u4f5c\u7528\u304c\u5c11\u306a\u304f\u3001\u306f\u308b\u304b\u306b\u5b89\u4fa1\u3067\u3059\u3002\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306f\u3001\u57f9\u990a\u3067\u78ba\u8a8d\u3055\u308c\u305f\u7279\u6b8a\u306a\u771f\u83cc\uff08Scedosporium\u3001Fusarium\u306a\u3069\uff09\u306b\u306e\u307f\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<h3>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u6295\u4e0e\u4e2d\u306b\u809d\u708e\u304c\u767a\u751f\u3057\u305f\u5834\u5408\u306f\u3069\u3046\u3059\u308c\u3070\u3088\u3044\u3067\u3059\u304b\uff1f<\/h3>\n<p>AST\/ALT\u304c\u6b63\u5e38\u4e0a\u9650\u306e5\u500d\u3092\u8d85\u3048\u308b\u5834\u5408\u3001\u307e\u305f\u306f\u3044\u305a\u308c\u304b\u306e\u4e0a\u6607\uff0b\u75c7\u72b6\uff08\u9ec4\u75b8\u3001\u5c3f\u306e\u8272\u306e\u6fc3\u3055\u3001\u53f3\u5b63\u808b\u90e8\u75db\uff09\u304c\u3042\u308b\u5834\u5408\u306f\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u3092\u4e2d\u6b62\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u4ee3\u66ff\u85ac\uff08\u9069\u5fdc\u306b\u5fdc\u3058\u3066\u30ab\u30b9\u30dd\u30d5\u30a1\u30f3\u30ae\u30f3\uff0f\u30df\u30ab\u30d5\u30a1\u30f3\u30ae\u30f3\uff0f\u30a2\u30e0\u30db\u30c6\u30ea\u30b7\u30f3B\uff0f\u30dd\u30b5\u30b3\u30ca\u30be\u30fc\u30eb\uff0f\u30a4\u30b5\u30d6\u30b3\u30ca\u30be\u30fc\u30eb\uff09\u306b\u5207\u308a\u66ff\u3048\u3066\u304f\u3060\u3055\u3044\u3002\u5c11\u91cf\u3067\u306e\u518d\u6295\u4e0e\u306f\u3001\u6ce8\u610f\u6df1\u3044\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306e\u4e0b\u3067\u53ef\u80fd\u306a\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<h3>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u3092PPI\u3068\u4f75\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306fCYP2C19\u3092\u963b\u5bb3\u3057\u3001\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb\u3068\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb\u306e\u8840\u4e2d\u6fc3\u5ea6\u3092\u7d042\u500d\u306b\u4e0a\u6607\u3055\u305b\u307e\u3059\u3002PPI\u3092\u7d99\u7d9a\u3059\u308b\u5834\u5408\u306f\u6295\u4e0e\u91cf\u3092\u534a\u6e1b\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb\u3068\u30e9\u30d9\u30d7\u30e9\u30be\u30fc\u30eb\u306f\u5f71\u97ff\u304c\u5c11\u306a\u3044\u3067\u3059\u3002\u3053\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306e\u8840\u4e2d\u6fc3\u5ea6\u306f\u6709\u610f\u306b\u5909\u5316\u3057\u307e\u305b\u3093\u3002<\/p>\n<h3>TDM\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f\u306a\u305c\u6700\u521d\u306f\u6bce\u9031\u884c\u3046\u306e\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u6cbb\u7642\u85ac\u7269\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\uff08TDM\uff09\u3068\u306f\u3001\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306e\u30c8\u30e9\u30d5\u8840\u6f3f\u4e2d\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u76ee\u6a19\u5024\u306f1\uff5e5.5 mg\/L\u3067\u3059\u30021\u672a\u6e80\u3067\u306f\u6cbb\u7642\u5931\u6557\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u30025.5\u8d85\u3067\u306f\u809d\u6bd2\u6027\u3001\u8133\u75c7\u3001\u8996\u899a\u969c\u5bb3\u306e\u30ea\u30b9\u30af\u304c\u3042\u308a\u307e\u3059\u3002CYP2C19\u306e\u907a\u4f1d\u5b50\u591a\u578b\u306b\u3088\u308a\u7528\u91cf\u53cd\u5fdc\u304c\u4e88\u6e2c\u3067\u304d\u306a\u3044\u305f\u3081\u3001\u4fb5\u8972\u6027\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u75c7\u3067\u306fTDM\u306f\u5fc5\u9808\u3067\u3059\u3002<\/p>\n<h2 id=\"storage\">\u4fdd\u7ba1\u65b9\u6cd5<\/h2>\n<p>\u9320\u5264\u306f\u5143\u306e\u5305\u88c5\u306e\u307e\u307e15\uff5e30\u00b0C\u3067\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u5149\u3092\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002\u4f7f\u7528\u671f\u9650\u3092\u904e\u304e\u305f\u3082\u306e\u306f\u4f7f\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u5b50\u4f9b\u306e\u624b\u306e\u5c4a\u304b\u306a\u3044\u3068\u3053\u308d\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h2>\u305d\u306e\u4ed6\u306e\u304a\u3059\u3059\u3081\u6297\u771f\u83cc\u85ac<\/h2>\n<p>\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u306f\u5c02\u9580\u7684\u306a\u6cbb\u7642\u85ac\u3067\u3059\u3002\u4ee5\u4e0b\u306b\u3001\u540c\u3058\u6709\u52b9\u6210\u5206\u3092\u5225\u306e\u30e1\u30fc\u30ab\u30fc\u304c\u88fd\u9020\u3057\u305f\u88fd\u54c1\u3068\u3001\u30dc\u30ea\u30b3\u30ca\u30be\u30fc\u30eb\u304c\u904e\u5270\u6cbb\u7642\u3068\u306a\u308b\u4e00\u822c\u7684\u306a\u9069\u5fdc\u75c7\u306b\u5bfe\u3059\u308b\u7b2c\u4e00\u9078\u629e\u306e\u6297\u771f\u83cc\u85ac\u3092\u63b2\u8f09\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ja\/zocon\/\"><strong>Zocon\uff08\u30d5\u30eb\u30b3\u30ca\u30be\u30fc\u30eb150mg\uff09<\/strong><\/a> \u2014 \u975e\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u6027\u30ab\u30f3\u30b8\u30c0\u306b\u5bfe\u3059\u308b\u7b2c\u4e00\u9078\u629e\u85ac\u3002\u5fcd\u5bb9\u6027\u826f\u597d\u3002<\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/sporanox-capsule\/\"><strong>Sporanox\uff08\u30b9\u30dd\u30e9\u30ce\u30c3\u30af\u30b9\u3001\u30a4\u30c8\u30e9\u30b3\u30ca\u30be\u30fc\u30eb100mg\uff09<\/strong><\/a> \u2014 \u4e8c\u5f62\u6027\u771f\u83cc\u75c7\u304a\u3088\u3073\u975e\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u6027\u7cf8\u72b6\u83cc\u306b\u3002<\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/zimig\/\"><strong>Zimig\uff08\u30b8\u30df\u30b0\u3001\u30c6\u30eb\u30d3\u30ca\u30d5\u30a3\u30f3250mg\uff09<\/strong><\/a> \u2014 \u76ae\u819a\u7cf8\u72b6\u83cc\u306b\u3088\u308b\u722a\u30fb\u76ae\u819a\u611f\u67d3\u75c7\uff08\u4fb5\u8972\u6027\u7cf8\u72b6\u83cc\u611f\u67d3\u75c7\u3067\u306f\u306a\u3044\uff09\u3002<\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/clocip\/\"><strong>Clocip\uff08\u30af\u30ed\u30c8\u30ea\u30de\u30be\u30fc\u30eb1%\uff09<\/strong><\/a> \u2014 \u8868\u5728\u6027\u30ab\u30f3\u30b8\u30c0\u75c7\u3001\u76ae\u819a\u7cf8\u72b6\u83cc\u6027\u767d\u766c\u306b\u3002<\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/loceryl-nail-liq\/\"><strong>Loceryl\uff08\u30a2\u30e2\u30ed\u30eb\u30d5\u30a3\u30f35%\uff09<\/strong><\/a> \u2014 \u8efd\u5ea6\u306e\u722a\u767d\u766c\u306b\u5bfe\u3059\u308b\u5916\u7528\u722a\u7528\u30e9\u30c3\u30ab\u30fc\u3002<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:12px 18px;margin:24px 0;font-size:0.95em;\"><strong>\u533b\u7642\u4e0a\u306e\u514d\u8cac\u4e8b\u9805.<\/strong> 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\u771f\u83cc\u611f\u67d3\u75c7\u306e\u8fc5\u901f\u306a\u7de9\u548c<br \/>\n\u2705 \u771f\u83cc\u306e\u52b9\u679c\u7684\u306a\u6839\u7d76<br \/>\n\u2705 \u5c02\u9580\u5bb6\u30ec\u30d3\u30e5\u30fc\u6e08\u307f\u306e\u4fe1\u983c\u6027<br \/>\n\u2705 \u5fcd\u5bb9\u6027\u306b\u512a\u308c\u3001\u526f\u4f5c\u7528\u306f\u4e00\u822c\u7684\u306a\u3082\u306e<br \/>\n\u2705 \u7c21\u4fbf\u306a\u6295\u4e0e<\/h5>\n<p><span style=\"color: #999999;\">Vorier 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