{"id":59206,"date":"2024-02-28T05:46:21","date_gmt":"2024-02-28T05:46:21","guid":{"rendered":"https:\/\/medsname.com\/nasdep\/"},"modified":"2026-05-01T10:49:15","modified_gmt":"2026-05-01T10:49:15","slug":"nasdep","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/nasdep\/","title":{"rendered":"Nasdep"},"content":{"rendered":"

<\/p>\n

\n

\u26a1 \u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc \u2014 Nasdep\u3068\u306f\uff1f<\/h3>\n
\n

Nasdep<\/strong> \u542b\u6709 \u30df\u30eb\u30bf\u30b6\u30d4\u30f3 30 mg<\/strong> WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\uff08Lupin Pharmaceuticals\uff09\u3088\u308a \u2014 \u52b9\u679c\u306e \u56db\u74b0\u7cfbNaSSA\u6297\u3046\u3064\u85ac\u3067<\/strong> \u72ec\u81ea\u306e\u4f5c\u7528\u6a5f\u5e8f\u3092\u6301\u3061\u307e\u3059\uff1a\u03b12\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u81ea\u5df1\u53d7\u5bb9\u4f53\u304a\u3088\u3073\u30d8\u30c6\u30ed\u53d7\u5bb9\u4f53\u3078\u306e\u62ee\u6297\u4f5c\u7528\u304c\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u3068\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u4e21\u65b9\u306e\u904a\u96e2\u3092\u4fc3\u9032\u3057\u30015-HT2\uff0f5-HT3\u53d7\u5bb9\u4f53\u3078\u306e\u62ee\u6297\u4f5c\u7528\u304c\u6d3b\u6027\u5316\u3055\u308c\u305f\u30bb\u30ed\u30c8\u30cb\u30f3\u3092SSRI\u306e\u526f\u4f5c\u7528\u3092\u5f15\u304d\u8d77\u3053\u3059\u53d7\u5bb9\u4f53\u304b\u3089\u9060\u3056\u3051\u307e\u3059\u3002\u6a19\u6e96\u7528\u91cf\uff1a \u5c31\u5bdd\u524d\u306b15\uff5e45 mg<\/strong> \uff08\u958b\u59cb\u7528\u91cf15 mg\u3001\u76ee\u6a19\u7528\u91cf30\uff5e45 mg\uff09\u3002\u4ee5\u4e0b\u306e\u75c7\u72b6\u3092\u4f34\u3046\u5927\u3046\u3064\u75c5\u6027\u969c\u5bb3\u306b\u7279\u306b\u63a8\u5968\u3055\u308c\u307e\u3059\uff1a \u4e0d\u7720\u3001\u98df\u6b32\u4f4e\u4e0b\u3001\u4f53\u91cd\u6e1b\u5c11\u3001\u307e\u305f\u306f\u6cbb\u7642\u62b5\u6297\u6027\u306e\u7126\u71e5\u6027\u3046\u3064\u75c5<\/strong>. \u9006\u8aac\u7684\u93ae\u9759\u30d1\u30bf\u30fc\u30f3<\/strong>\uff1a\u9ad8\u7528\u91cf\uff0845 mg\uff09\u6642\u3088\u308a\u3082\u4f4e\u7528\u91cf\uff0815 mg\uff09\u6642\u306e\u307b\u3046\u304c\u93ae\u9759\u4f5c\u7528\u304c\u5f37\u304f\u73fe\u308c\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u9ad8\u7528\u91cf\u3067\u306f\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u6d3b\u6027\u304c\u3088\u308a\u52d5\u54e1\u3055\u308c\u308b\u305f\u3081\u3067\u3059\u3002\u30d1\u30ed\u30ad\u30bb\u30c1\u30f3\u3068\u4e26\u3093\u3067\u6297\u3046\u3064\u85ac\u306e\u4e2d\u3067\u6700\u3082\u9855\u8457\u306a\u4f53\u91cd\u5897\u52a0\u304c\u8a8d\u3081\u3089\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n

\nMedsBase\u3067\u5f97\u3089\u308c\u308b\u3082\u306e\uff1a<\/strong> WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143 \u00b7 \u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305 \u00b7 \u5168\u4e16\u754c\u914d\u9001 \u00b7 1,400\u4ef6\u4ee5\u4e0a\u306e\u78ba\u8a8d\u6e08\u307f \u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a>\n<\/div>\n

\ud83d\udce6 \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u3001\u5f53\u5e97\u306e \u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u5546\u54c1\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u306f\u3001\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n

MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n

\u5f53\u5e97\u306e\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306f\u3001WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4ed5\u5165\u308c\u3001\u5168\u4e16\u754c\u3078\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u7121\u5730\u306e\u68b1\u5305\u3067\u767a\u9001\u3055\u308c\u307e\u3059\u3002\u914d\u9001\u7bb1\u306e\u5916\u5074\u306b\u306f\u533b\u85ac\u54c1\u540d\u306f\u4e00\u5207\u8a18\u8f09\u3055\u308c\u307e\u305b\u3093\u3002\u30ab\u30fc\u30c9\u6c7a\u6e08\u306f\u3001\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u3092\u7d4c\u7531\u3057\u3066\u51e6\u7406\u3055\u308c\uff08\u660e\u7d30\u66f8\u306e\u8868\u793a\u306b\u306f\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u306e\u307f\u304c\u8a18\u8f09\u3055\u308c\u3001\u300cMedsBase\u300d\u3084\u533b\u85ac\u54c1\u540d\u304c\u8868\u793a\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\uff09\u3001\u6697\u53f7\u8cc7\u7523\u3084SEPA\u9280\u884c\u632f\u8fbc\u3082\u3054\u5229\u7528\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306b\u306f\u3001\u5f53\u5e97\u306e\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc\u304c\u9069\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n

\u91cd\u8981 \u2014 \u3053\u308c\u306f\u72b6\u6cc1\u306b\u5fdc\u3058\u305f\u4e0d\u5b89\u306b\u5bfe\u3059\u308b\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/strong> Nasdep\u306f\u3001 \u56db\u74b0\u7cfb\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u30fb\u7279\u7570\u7684\u30bb\u30ed\u30c8\u30cb\u30f3\u4f5c\u52d5\u6027\u6297\u3046\u3064\u85ac\uff08NaSSA\uff09\u3067\u3042\u308a\u3001<\/strong>, \u3067\u3042\u308a\u3001\u6570\u9031\u9593\u304b\u3051\u3066\u51e6\u65b9\u30fb\u6f38\u5897\u3055\u308c\u308b\u3001 \u5927\u3046\u3064\u75c5\u6027\u969c\u5bb3\uff08MDD\uff09\u3001\u7279\u306b\u9855\u8457\u306a\u4e0d\u7720\u3001\u98df\u6b32\u4f4e\u4e0b\u3001\u4f53\u91cd\u6e1b\u5c11\u3001\u307e\u305f\u306f\u7126\u71e5\u3092\u4f34\u3046\u5834\u5408\u306b\u7528\u3044\u3089\u308c\u307e\u3059<\/strong>. \u306e\u6cbb\u7642\u85ac\u3067\u3059\u3002\u3053\u308c\u306f \u3057\u307e\u305b\u3093<\/strong> \u98db\u884c\u6a5f\u642d\u4e57\u3001\u4eba\u524d\u3067\u306e\u30b9\u30d4\u30fc\u30c1\u3001\u8a66\u9a13\u306a\u3069\u3001\u6025\u6027\u306e\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u4e0d\u5b89\u306b\u5bfe\u3059\u308b\u9069\u5207\u306a\u85ac\u5264\u306f\u3001\u30d9\u30fc\u30bf\u906e\u65ad\u85ac\uff08\u30d7\u30ed\u30d7\u30e9\u30ce\u30ed\u30fc\u30eb\uff09\u3001\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u7cfb\u85ac\u3001\u307e\u305f\u306f\u30d2\u30c9\u30ed\u30ad\u30b7\u30b8\u30f3\u304c\u81e8\u5e8a\u7684\u306b\u9069\u5207\u3067\u3059\u3002\u6c17\u5206\u969c\u5bb3\u3001\u4e0d\u5b89\u969c\u5bb3\u3001\u7cbe\u795e\u969c\u5bb3\u306e\u8a3a\u65ad\u3092\u53d7\u3051\u3066\u3044\u306a\u3044\u5834\u5408\u306f\u3001\u3053\u306e\u85ac\u306e\u670d\u7528\u3092\u958b\u59cb\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/div>\n
FDA\u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a \u2014 \u81ea\u6bba\u5ff5\u616e\u3002<\/strong> \u3059\u3079\u3066\u306e\u6297\u3046\u3064\u85ac\u306f\u300125\u6b73\u672a\u6e80\u306e\u5c0f\u5150\u3001\u9752\u5e74\u3001\u82e5\u5e74\u6210\u4eba\u306b\u304a\u3044\u3066\u3001\u7279\u306b\u6cbb\u7642\u958b\u59cb\u5f8c\u6570\u9031\u9593\u307e\u305f\u306f\u7528\u91cf\u5909\u66f4\u5f8c\u306b\u3001\u81ea\u6bba\u5ff5\u616e\u3084\u81ea\u6bba\u884c\u52d5\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u3044\u3046FDA\u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a\u3092\u4f34\u3044\u307e\u3059\u3002\u3054\u5bb6\u65cf\u3084\u51e6\u65b9\u533b\u306f\u3001\u3053\u306e\u5e74\u9f62\u5c64\u306b\u304a\u3044\u3066\u6c17\u5206\u306e\u60aa\u5316\u3001\u7126\u71e5\u3001\u81ea\u6bba\u5ff5\u616e\u304c\u307f\u3089\u308c\u306a\u3044\u304b\u6ce8\u610f\u6df1\u304f\u89b3\u5bdf\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/div>\n

Nasdep\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h2>\n

Nasdep\u306f\u7d4c\u53e3\u9320\u3067\u3001 \u30df\u30eb\u30bf\u30b6\u30d4\u30f3 30 mg<\/strong> Lupin Pharmaceuticals\u306b\u3088\u3063\u3066\u88fd\u9020\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\uff08\u7c73\u56fd\u3067\u306e\u30d6\u30e9\u30f3\u30c9\u540d\u306f Remeron<\/strong>) \u306f \u56db\u74b0\u7cfb\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u30fb\u7279\u7570\u7684\u30bb\u30ed\u30c8\u30cb\u30f3\u4f5c\u52d5\u6027\u6297\u3046\u3064\u85ac\uff08NaSSA\uff09\u3067\u3042\u308a\u3001<\/strong> 1994\u5e74\u306bOrganon\u306b\u3088\u308a\u767a\u58f2\u3055\u308c\u307e\u3057\u305f\u3002\u305d\u306e\u4f5c\u7528\u6a5f\u5e8f\u306f\u3001\u65e5\u5e38\u7684\u306b\u4f7f\u7528\u3055\u308c\u308b\u4ed6\u306e\u6297\u3046\u3064\u85ac\u3068\u306f\u7570\u306a\u308a\u307e\u3059\uff1a\u518d\u53d6\u308a\u8fbc\u307f\u3092\u963b\u5bb3\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u30b7\u30ca\u30d7\u30b9\u524d\u03b12\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u53d7\u5bb9\u4f53\u306b\u62ee\u6297\u3057\uff08\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u306e\u653e\u51fa\u3092\u4fc3\u9032\uff09\u3001\u3055\u3089\u306b\u30bb\u30ed\u30c8\u30cb\u30f3\u4f5c\u52d5\u6027\u795e\u7d4c\u7d42\u672b\u306e\uff08\u7570\u7a2e\u53d7\u5bb9\u4f53\u52b9\u679c\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u306e\u653e\u51fa\u3092\u4fc3\u9032\uff09\u3001\u540c\u6642\u306b5-HT\u306b\u62ee\u6297\u3057\u307e\u30592A<\/sub>, \u30015-HT2C<\/sub>, \u3001\u304a\u3088\u30735-HT3<\/sub> \u53d7\u5bb9\u4f53\u30025-HT2<\/sub> \u304a\u3088\u30735-HT3<\/sub> \u906e\u65ad\u306b\u3088\u308a\u3001\u5897\u52a0\u3057\u305f\u30bb\u30ed\u30c8\u30cb\u30f3\u304cSSRI\u306e\u526f\u4f5c\u7528\uff08\u6027\u6a5f\u80fd\u969c\u5bb3\u3001\u4e0d\u5b89\u3001\u80c3\u8178\u4e0d\u5feb\u611f\uff09\u306e\u539f\u56e0\u53d7\u5bb9\u4f53\u304b\u3089\u9038\u3089\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u3053\u308c\u306f\u5f37\u529b\u306aH1<\/sub> \u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u3067\u3042\u308a\u3001\u93ae\u9759\u3068\u98df\u6b32\u523a\u6fc0\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/p>\n

\u627f\u8a8d\u3055\u308c\u305f\u9069\u5fdc\u75c7<\/h2>\n
    \n
  • \u5927\u3046\u3064\u75c5\u6027\u969c\u5bb3\uff08MDD\uff09<\/strong> \u2014 \u7279\u306b\u4e0d\u7720\u3001\u98df\u6b32\u4e0d\u632f\u3001\u4f53\u91cd\u6e1b\u5c11\u3001\u307e\u305f\u306f\u7126\u71e5\u611f\u304c\u9855\u8457\u306a\u5834\u5408<\/li>\n
  • \u9069\u5fdc\u5916\u4f7f\u7528\uff1a\u4e0d\u5b89\u969c\u5bb3\uff08\u5168\u822c\u6027\u4e0d\u5b89\u969c\u5bb3\u3001\u793e\u4ea4\u4e0d\u5b89\u969c\u5bb3\u3001\u5fc3\u7684\u5916\u50b7\u5f8c\u30b9\u30c8\u30ec\u30b9\u969c\u5bb3\uff09\u3001\u6162\u6027\u4e0d\u7720\u75c7\uff08\u4f4e\u7528\u91cf7.5\uff5e15 mg\uff09\u3001\u96e3\u6cbb\u6027\u306e\u304b\u3086\u307f\u3001\u6162\u6027\u5410\u304d\u6c17\u3001\u98df\u6b32\u4e0d\u632f\/\u60aa\u6db2\u8cea\u3001\u30db\u30c3\u30c8\u30d5\u30e9\u30c3\u30b7\u30e5<\/li>\n
  • \u6cbb\u7642\u62b5\u6297\u6027\u3046\u3064\u75c5\uff1a\u5c02\u9580\u533b\u306e\u76e3\u7763\u4e0b\u3067\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\u3068\u4f75\u7528\uff08\u300c\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u30fb\u30ed\u30b1\u30c3\u30c8\u71c3\u6599\u300d\uff09<\/li>\n<\/ul>\n

    \u7528\u6cd5<\/h2>\n\n\n\n\n\n\n\n\n
    \u9069\u5fdc\u75c7<\/th>\n\u958b\u59cb<\/th>\n\u76ee\u6a19\u7528\u91cf<\/th>\n\u6700\u5927<\/th>\n\u5099\u8003<\/th>\n<\/tr>\n<\/thead>\n
    MDD<\/td>\n\u5c31\u5bdd\u524d\u306b15 mg\u30921\u9031\u9593<\/td>\n\u5c31\u5bdd\u524d\u306b30\uff5e45 mg<\/td>\n45 mg\/\u65e5<\/td>\n\u9ad8\u7528\u91cf\u3067\u306f\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u304c\u9ad8\u307e\u308a\u3001\u9006\u8aac\u7684\u306b\u93ae\u9759\u4f5c\u7528\u306f\u5f31\u307e\u308a\u307e\u3059\u3002<\/td>\n<\/tr>\n
    \u9069\u5fdc\u5916\u4f7f\u7528\uff1a\u4e0d\u7720\u75c7<\/td>\n\u5c31\u5bdd\u524d\u306b7.5\uff5e15 mg<\/td>\n\u5c31\u5bdd\u524d\u306b7.5\uff5e15 mg<\/td>\n\u2014<\/td>\n\u77ed\u671f\u4f7f\u7528\u306b\u9650\u3063\u3066\u304f\u3060\u3055\u3044\u3002\u4f4e\u7528\u91cf\u3067\u3082\u4f53\u91cd\u5897\u52a0\u306f\u5b9f\u969b\u306b\u751f\u3058\u307e\u3059\u3002<\/td>\n<\/tr>\n
    \u9ad8\u9f62\u8005<\/td>\n\u5c31\u5bdd\u524d\u306b7.5\uff5e15 mg<\/td>\n\u5c31\u5bdd\u524d\u306b15\uff5e30mg<\/td>\n1\u65e530mg<\/td>\n\u958b\u59cb\u7528\u91cf\u3092\u6e1b\u3089\u3059\uff1b\u8d77\u7acb\u6027\u4f4e\u8840\u5727\u3068\u93ae\u9759\u4f5c\u7528\u304c\u5f37\u304f\u306a\u308b<\/td>\n<\/tr>\n
    \u809d\u969c\u5bb3\/\u814e\u969c\u5bb3<\/td>\n\u5c31\u5bdd\u524d\u306b15mg<\/td>\n1\u65e5\u6700\u592730mg<\/td>\n\u2014<\/td>\n\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u4f4e\u4e0b \u2014 \u3088\u308a\u7de9\u3084\u304b\u306a\u7528\u91cf\u6f38\u5897<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u526f\u4f5c\u7528<\/h2>\n

    \u6a5f\u5e8f\u5225 \u526f\u4f5c\u7528\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n
    \u4f5c\u7528\u6a5f\u5e8f<\/th>\n\u526f\u4f5c\u7528<\/th>\n\u5099\u8003<\/th>\n<\/tr>\n<\/thead>\n
    H1<\/sub> \u906e\u65ad<\/td>\n\u93ae\u9759\u30fb\u4f53\u91cd\u5897\u52a0\uff08\u98df\u6b32\u523a\u6fc0\uff09<\/td>\n\u4f53\u91cd\u5897\u52a0\u306f\u9855\u8457\u3067\u3001\u901a\u5e386\u304b\u6708\u30674\uff5e7kg\u5897\u52a0\u3057\u307e\u3059\u3002\u93ae\u9759\u4f5c\u7528\u306f\u9ad8\u7528\u91cf\u3067\u306f\u9006\u8aac\u7684\u306b\u8efd\u6e1b\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n
    \u03b11\u906e\u65ad<\/td>\n\u8d77\u7acb\u6027\u4f4e\u8840\u5727\u3001\u3081\u307e\u3044<\/td>\n\u7279\u306b\u9ad8\u9f62\u8005\u3067\u306f \u2014 \u81e5\u4f4d\u30fb\u7acb\u4f4d\u8840\u5727\u3092\u78ba\u8a8d<\/td>\n<\/tr>\n
    \u6297\u30b3\u30ea\u30f3\u4f5c\u7528\uff08\u8efd\u5ea6\uff09<\/td>\n\u53e3\u306e\u6e07\u304d<\/td>\n\u4e09\u74b0\u7cfb\u6297\u3046\u3064\u85ac\u3088\u308a\u5c11\u306a\u3044<\/td>\n<\/tr>\n
    5-HT3<\/sub> antagonism<\/td>\n\u5236\u5410\u4f5c\u7528\uff1b\u6d88\u5316\u5668\u75c7\u72b6\u306e\u8efd\u6e1b<\/td>\n\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u304cSSRI\/SNRI\u3088\u308a\u5410\u304d\u6c17\u304c\u306f\u308b\u304b\u306b\u5c11\u306a\u3044\u7406\u7531<\/td>\n<\/tr>\n
    \u305d\u306e\u4ed6<\/td>\n\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001\u4e2d\u6027\u8102\u80aa\u3001\u8840\u7cd6\u5024\u306e\u4e0a\u6607<\/td>\n6\uff5e12\u304b\u6708\u6642\u70b9\u3067\u306e\u4ee3\u8b1d\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u304c\u6709\u7528<\/td>\n<\/tr>\n
    \u307e\u308c<\/td>\n\u7121\u9846\u7c92\u7403\u75c7\uff081\/1000\uff09<\/td>\n\u6700\u521d\u306e6\u9031\u9593\u306b\u6301\u7d9a\u3059\u308b\u767a\u71b1\u3001\u54bd\u982d\u75db\u3001\u7c98\u819c\u6f70\u760d\u304c\u3042\u308c\u3070\u4e2d\u6b62\u3057\u3001\u5168\u8840\u7403\u8a08\u7b97\uff08FBC\uff09\u3092\u78ba\u8a8d<\/td>\n<\/tr>\n
    \u307e\u308c<\/td>\n\u4f4e\u30ca\u30c8\u30ea\u30a6\u30e0\u8840\u75c7\uff08SIADH\uff09<\/td>\n\u9ad8\u9f62\u8005\u3067\u30ea\u30b9\u30af\u304c\u6700\u3082\u9ad8\u3044<\/td>\n<\/tr>\n
    \u307e\u308c<\/td>\n\u3080\u305a\u3080\u305a\u811a\u75c7\u5019\u7fa4\u3001\u9bae\u660e\u306a\u5922<\/td>\n\u60a3\u8005\u3055\u3093\u3078\u306e\u670d\u85ac\u6307\u5c0e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    \u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306e\u93ae\u9759\u4f5c\u7528\u306e\u30d1\u30e9\u30c9\u30c3\u30af\u30b9<\/h2>\n

    \u591a\u304f\u306e\u60a3\u8005\u304c\u6df7\u4e71\u3057\u3066\u3044\u308b\u306e\u306f\u3001\u30df\u30eb\u30bf\u30b6\u30d4\u30f315mg\u304c \u3088\u308a\u93ae\u9759\u4f5c\u7528\u304c\u5f37\u3044<\/strong> \u30df\u30eb\u30bf\u30b6\u30d4\u30f330\uff5e45mg\u3088\u308a\u3082\u3002\u3053\u308c\u306f\u5b9f\u969b\u306b\u3042\u308a\u3001\u85ac\u7406\u5b66\u7684\u306b\u5341\u5206\u8aac\u660e\u3055\u308c\u3066\u3044\u307e\u3059\uff1a\u4f4e\u7528\u91cf\u3067\u306f\u3001H1<\/sub> \u906e\u65ad\u304c\u512a\u4f4d\u306b\u306a\u308a\u307e\u3059\uff08\u93ae\u9759\u4f5c\u7528\uff09\u3002\u9ad8\u7528\u91cf\u3067\u306f\u3001\u03b12\u906e\u65ad\u306b\u3088\u308b\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u306e\u5897\u5f37\u304c\u3088\u308a\u6d3b\u6027\u5316\u3092\u4fc3\u3057\u3001\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u4f5c\u7528\u306b\u3088\u308b\u93ae\u9759\u3092\u90e8\u5206\u7684\u306b\u76f8\u6bba\u3057\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u300115mg\u3067\u958b\u59cb\u3057\u3066\u904e\u5ea6\u306e\u7720\u6c17\u3092\u611f\u3058\u308b\u60a3\u8005\u3055\u3093\u306f\u3001\u6642\u306b 30mg\u306b\u5897\u91cf\u3059\u308b\u3053\u3068\u3067<\/strong>, \u3001\u6e1b\u91cf\u3067\u306f\u306a\u304f\u3002\u3053\u308c\u306f\u76f4\u611f\u306b\u53cd\u3057\u3066\u304a\u308a\u3001\u51e6\u65b9\u6642\u306b\u8aac\u660e\u3059\u308b\u4fa1\u5024\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

    \u85ac\u7269\u76f8\u4e92\u4f5c\u7528<\/h2>\n

    \u7d76\u5bfe\u7981\u5fcc<\/strong>\uff1aMAO\u963b\u5bb3\u85ac\uff0814\u65e5\u9593\u306e\u4f11\u85ac\u671f\u9593\uff09\u3002\u30bb\u30ed\u30c8\u30cb\u30f3\u75c7\u5019\u7fa4\u306e\u30ea\u30b9\u30af\u306fSSRI\u3088\u308a\u4f4e\u3044\u3067\u3059\u3002\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306f\u518d\u53d6\u308a\u8fbc\u307f\u963b\u5bb3\u3092\u4ecb\u3057\u3066\u30b7\u30ca\u30d7\u30b9\u9593\u9699\u306e\u30bb\u30ed\u30c8\u30cb\u30f3\u3092\u5897\u52a0\u3055\u305b\u306a\u3044\u305f\u3081\u3067\u3059\u304c\u3001\u8b66\u544a\u306f\u4f9d\u7136\u3068\u3057\u3066\u6709\u52b9\u3067\u3059\u3002<\/p>\n

    \u76f8\u52a0\u7684\u306a\u4e2d\u67a2\u795e\u7d4c\u6291\u5236\u4f5c\u7528<\/strong>\uff1a\u30a2\u30eb\u30b3\u30fc\u30eb\u3001\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u7cfb\u85ac\u3001\u30aa\u30d4\u30aa\u30a4\u30c9\u3001\u93ae\u9759\u4f5c\u7528\u306e\u3042\u308b\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u3001\u7761\u7720\u85ac\u3002<\/p>\n

    CYP2D6 \\\/ CYP3A4 \u57fa\u8cea<\/strong>\uff1a\u5f37\u529b\u306a\u963b\u5bb3\u5264\u306b\u3088\u308a\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u307e\u3059\uff1b\u30d1\u30ed\u30ad\u30bb\u30c1\u30f3\u3001\u30d5\u30eb\u30aa\u30ad\u30bb\u30c1\u30f3\u3001\u30b1\u30c8\u30b3\u30ca\u30be\u30fc\u30eb\u3001\u30ea\u30c8\u30ca\u30d3\u30eb\u3068\u306e\u4f75\u7528\u306b\u306f\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

    \u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n

    Nasdep\uff08\u30ca\u30b9\u30c7\u30c3\u30d7\uff09\u306f\u52b9\u679c\u304c\u73fe\u308c\u308b\u307e\u3067\u3069\u306e\u304f\u3089\u3044\u304b\u304b\u308a\u307e\u3059\u304b\uff1f<\/h3>\n

    \u7761\u7720\u3068\u98df\u6b32\u306f\u901a\u5e381\uff5e2\u9031\u9593\u4ee5\u5185\u306b\u6539\u5584\u3057\u307e\u3059\u3002\u5b8c\u5168\u306a\u6c17\u5206\u53cd\u5fdc\u306f\u3046\u3064\u75c5\uff08MDD\uff09\u3067\u306f\u901a\u5e384\uff5e6\u9031\u9593\u3067\u73fe\u308c\u307e\u3059\u3002\u591a\u304f\u306e\u51e6\u65b9\u533b\u306f\u3001\u4e0d\u7720\u3068\u4f53\u91cd\u6e1b\u5c11\u306e\u3042\u308b\u60a3\u8005\u306b\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u3092\u8003\u616e\u3057\u307e\u3059\u3002\u306a\u305c\u306a\u3089\u3001\u597d\u307e\u3057\u3044\u526f\u4f5c\u7528\u304c\u60a3\u8005\u3055\u3093\u306b\u3068\u3063\u3066\u4e0d\u5229\u306b\u3067\u306f\u306a\u304f\u3001\u3080\u3057\u308d\u6709\u5229\u306b\u50cd\u304f\u304b\u3089\u3067\u3059\u3002<\/p>\n

    Nasdep\uff08\u30ca\u30b9\u30c7\u30c3\u30d7\uff09\u304c\u4f53\u91cd\u5897\u52a0\u3092\u5f15\u304d\u8d77\u3053\u3059\u306e\u306f\u306a\u305c\u3067\u3059\u304b\uff1f<\/h3>\n

    \u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306f\u5f37\u529b\u306aH1<\/sub> \u6297\u30d2\u30b9\u30bf\u30df\u30f3\u85ac\u304a\u3088\u30735-HT2C<\/sub> \u62ee\u6297\u4f5c\u7528\u306b\u3088\u308a\u98df\u6b32\u304c\u523a\u6fc0\u3055\u308c\u307e\u3059\u3002\u4f53\u91cd\u5897\u52a0\u306f\u7528\u91cf\u306b\u4f9d\u5b58\u305b\u305a\u3001\u591a\u304f\u306e\u5834\u54086\u304b\u6708\u30674\uff5e7 kg\u3068\u9855\u8457\u3067\u3059\u3002\u3046\u3064\u75c5\u306b\u95a2\u9023\u3057\u305f\u4f53\u91cd\u6e1b\u5c11\u304c\u3042\u308b\u60a3\u8005\u306b\u306f\u6cbb\u7642\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u305d\u3046\u3067\u306a\u3044\u60a3\u8005\u306b\u3068\u3063\u3066\u306f\u85ac\u5264\u5909\u66f4\u306e\u4e3b\u306a\u7406\u7531\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n

    \u3046\u3064\u75c5\u3067\u306f\u306a\u3044\u4e0d\u7720\u306b\u5bfe\u3057\u3066Nasdep\u3092\u670d\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n

    \u4ed6\u306e\u7761\u7720\u85ac\u304c\u52b9\u679c\u3092\u793a\u3055\u306a\u304b\u3063\u305f\u6162\u6027\u4e0d\u7720\u75c7\u306e\u60a3\u8005\u306b\u5bfe\u3057\u3066\u3001\u4f4e\u7528\u91cf\uff087.5\uff5e15 mg\uff09\u3067\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4f53\u91cd\u5897\u52a0\u3068\u93ae\u9759\u4f5c\u7528\u304c\u9577\u671f\u306b\u308f\u305f\u3063\u3066\u6301\u7d9a\u3059\u308b\u305f\u3081\u3001\u7b2c\u4e00\u9078\u629e\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

    \u7528\u91cf\u306b\u3088\u308b\u9006\u8aac\u7684\u306a\u4f5c\u7528\u304c\u751f\u3058\u308b\u306e\u306f\u306a\u305c\u3067\u3059\u304b\uff1f<\/h3>\n

    15 mg\u3067\u306fH\u2081\u53d7\u5bb9\u4f53\u906e\u65ad\uff08\u93ae\u9759\u4f5c\u7528\uff09\u304c\u512a\u52e2\u306b\u306a\u308a\u307e\u3059\u300230\uff5e45 mg\u3067\u306f\u3001\u03b1\u2082\u53d7\u5bb9\u4f53\u62ee\u6297\u4f5c\u7528\u306b\u3088\u308b\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u306e\u5897\u5f37\u304c\u3088\u308a\u6d3b\u6027\u5316\u3092\u3082\u305f\u3089\u3057\u3001\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u4f5c\u7528\u306b\u3088\u308b\u93ae\u9759\u3092\u90e8\u5206\u7684\u306b\u76f8\u6bba\u3057\u307e\u3059\u300215 mg\u3067\u3075\u3089\u3064\u304d\u304c\u6b8b\u308b\u60a3\u8005\u306f\u300130 mg\u306b\u5897\u91cf\u3059\u308b\u3053\u3068\u3067\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u30021<\/sub> \u906e\u65ad\u4f5c\u7528\uff08\u93ae\u9759\uff09\u304c\u512a\u52e2\u3067\u3059\u300230\uff5e45mg\u3067\u306f\u3001\u03b12\u53d7\u5bb9\u4f53\u62ee\u6297\u4f5c\u7528\u306b\u3088\u308b\u30ce\u30eb\u30a2\u30c9\u30ec\u30ca\u30ea\u30f3\u4f5c\u52d5\u6027\u306e\u5897\u5f37\u304c\u3088\u308a\u6d3b\u6027\u5316\u3092\u4fc3\u3057\u3001\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u4f5c\u7528\u306b\u3088\u308b\u93ae\u9759\u3092\u90e8\u5206\u7684\u306b\u76f8\u6bba\u3057\u307e\u3059\u3002\u60a3\u8005\u69d8\u306f\u300115mg\u3067\u611f\u3058\u308b\u7720\u6c17\u309230mg\u306b\u5897\u91cf\u3059\u308b\u3053\u3068\u3067\u89e3\u6d88\u3067\u304d\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

    Nasdep\u306f\u6027\u7684\u306a\u526f\u4f5c\u7528\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u304b\uff1f<\/h3>\n

    SSRI\u3088\u308a\u306f\u308b\u304b\u306b\u5c11\u306a\u3044 \u2014 5-HT2<\/sub> \u306f\u3044\u3002\u30d9\u30f3\u30e9\u30d5\u30a1\u30ad\u30b7\u30f3\u3068\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306e\u4f75\u7528\u306f\u3001\u975e\u516c\u5f0f\u306b\u300c\u30ab\u30ea\u30d5\u30a9\u30eb\u30cb\u30a2\u30fb\u30ed\u30b1\u30c3\u30c8\u71c3\u6599\u300d\u3068\u547c\u3070\u308c\u3001\u6cbb\u7642\u62b5\u6297\u6027\u3046\u3064\u75c5\u306b\u5bfe\u3059\u308b\u6700\u3082\u30a8\u30d3\u30c7\u30f3\u30b9\u306e\u3042\u308b\u6226\u7565\u306e\u4e00\u3064\u3067\u3059\u3002\u5c02\u9580\u533b\u306e\u76e3\u7763\u4e0b\u3067\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n

    Nasdep\u306f\u598a\u5a20\u4e2d\u306b\u5b89\u5168\u3067\u3059\u304b\uff1f<\/h3>\n

    \u5b89\u5168\u6027\u30c7\u30fc\u30bf\u306f\u9650\u3089\u308c\u3066\u304a\u308a\u3001\u7b2c\u4e00\u9078\u629e\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002SSRI\uff08\u30bb\u30eb\u30c8\u30e9\u30ea\u30f3\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\uff09\u306b\u306f\u3001\u3088\u308a\u5927\u898f\u6a21\u306a\u767b\u9332\u30c7\u30fc\u30bf\u304c\u3042\u308a\u307e\u3059\u3002\u51e6\u65b9\u533b\u3068\u500b\u5225\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n

    Nasdep\u306f\u598a\u5a20\u4e2d\u306b\u5b89\u5168\u3067\u3059\u304b\uff1f<\/h3>\n

    \u5b89\u5168\u6027\u30c7\u30fc\u30bf\u304c\u9650\u3089\u308c\u3066\u3044\u308b \u2015 \u7b2c\u4e00\u9078\u629e\u85ac\u3067\u306f\u306a\u3044\u3002SSRI\uff08\u30bb\u30eb\u30c8\u30e9\u30ea\u30f3\u304c\u671b\u307e\u3057\u3044\uff09\u306f\u3001\u3088\u308a\u591a\u304f\u306e\u30ec\u30b8\u30b9\u30c8\u30ea\u30c7\u30fc\u30bf\u304c\u3042\u308a\u307e\u3059\u3002\u51e6\u65b9\u533b\u3068\u500b\u5225\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/p>\n

    \u70b9\u773c\u3092\u5fd8\u308c\u305f\u5834\u5408\u306f\u3069\u3046\u306a\u308a\u307e\u3059\u304b\uff1f<\/h3>\n

    \u601d\u3044\u51fa\u3057\u305f\u3089\u3059\u3050\u306b\u670d\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u305f\u3060\u3057\u3001\u6b21\u306e\u670d\u7528\u6642\u9593\u304c\u8fd1\u3044\u5834\u5408\u306f\u3001\u4e8c\u91cd\u306b\u670d\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306f\u534a\u6e1b\u671f\u304c\u9577\u304f\uff0820\uff5e40\u6642\u9593\uff09\u30011\u56de\u670d\u7528\u3092\u5fd8\u308c\u3066\u3082\u307b\u3068\u3093\u3069\u554f\u984c\u306b\u306a\u308a\u307e\u305b\u3093\u3002<\/p>\n

    Nasdep\u306f\u3069\u306e\u3088\u3046\u306b\u4e2d\u6b62\u3059\u308c\u3070\u3088\u3044\u3067\u3059\u304b\uff1f<\/h3>\n

    \u30df\u30eb\u30bf\u30b6\u30d4\u30f3\u306fSSRIs\/SNRIs\u3088\u308a\u3082\u96e2\u8131\u75c7\u5019\u7fa4\u304c\u8efd\u5ea6\u3067\u3059\u30022\uff5e4\u9031\u9593\u3054\u3068\u306b15mg\u305a\u3064\u6e1b\u91cf\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u7761\u7720\u3084\u98df\u6b32\u306e\u5909\u5316\u304c\u518d\u3073\u73fe\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059 \u2014 \u3054\u7559\u610f\u304f\u3060\u3055\u3044\u3002<\/p>\n

    Nasdep\u306f\u3069\u306e\u3088\u3046\u306b\u4fdd\u7ba1\u3059\u3079\u304d\u3067\u3059\u304b\uff1f<\/h3>\n

    15\uff5e30\u2103\u3067\u3001\u6e7f\u6c17\u3084\u76f4\u5c04\u65e5\u5149\u3092\u907f\u3051\u3001\u5143\u306e\u30d6\u30ea\u30b9\u30bf\u30fc\u30d1\u30c3\u30b1\u30fc\u30b8\u306b\u5165\u308c\u305f\u307e\u307e\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u304a\u5b50\u69d8\u306e\u624b\u306e\u5c4a\u304b\u306a\u3044\u5834\u6240\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

    \u533b\u7642\u4e0a\u306e\u514d\u8cac\u4e8b\u9805\uff1a<\/strong> \u3053\u306e\u30da\u30fc\u30b8\u306e\u60c5\u5831\u306f\u3001\u51e6\u65b9\u3055\u308c\u305f\u7cbe\u795e\u79d1\u306e\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u6210\u4eba\u3092\u5bfe\u8c61\u3068\u3057\u3066\u304a\u308a\u3001\u500b\u5225\u306e\u533b\u7642\u30b1\u30a2\u306e\u4ee3\u308f\u308a\u3068\u306a\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u6297\u3046\u3064\u85ac\u3001\u6297\u7cbe\u795e\u75c5\u85ac\u3001\u304a\u3088\u3073\u95a2\u9023\u3059\u308b\u85ac\u5264\u306f\u3001\u4ed6\u306e\u85ac\u5264\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u3001\u304a\u3088\u3073\u65e2\u5f80\u75c7\u3068\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u65b0\u3057\u3044\u85ac\u306e\u958b\u59cb\u3001\u7528\u91cf\u5909\u66f4\u3001\u307e\u305f\u306f\u4e2d\u6b62\u306e\u8a08\u753b\u306b\u3064\u3044\u3066\u306f\u3001\u8cc7\u683c\u306e\u3042\u308b\u51e6\u65b9\u533b\u3068\u76f8\u8ac7\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u81ea\u6bba\u5ff5\u616e\u3001\u8e81\u72b6\u614b\u3001\u91cd\u5ea6\u306e\u30a2\u30ab\u30b7\u30b8\u30a2\uff08\u9759\u5750\u4e0d\u80fd\uff09\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u75c7\u5019\u7fa4\u306e\u5146\u5019\uff08\u9ad8\u71b1\u3001\u932f\u4e71\u3001\u7b4b\u8089\u306e\u786c\u76f4\u3001\u983b\u8108\uff09\u3001\u307e\u305f\u306f\u60aa\u6027\u75c7\u5019\u7fa4\u304c\u73fe\u308c\u305f\u5834\u5408\u306f\u3001\u76f4\u3061\u306b\u6551\u6025\u533b\u7642\u3092\u53d7\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/div>\n

    <\/p>\n

    \u3067\u304a\u5ba2\u69d8\u304c\u4f75\u305b\u3066\u95b2\u89a7\u3055\u308c\u308b\u4ed6\u306e\u88fd\u54c1\uff1a<\/h3>\n

    \u305d\u306e\u4ed6\u306e\u88fd\u54c1\u306e \u6162\u6027\u75be\u60a3<\/strong> \u304a\u5ba2\u69d8\u304c\u4f75\u305b\u3066\u3054\u89a7\u306b\u306a\u308b:<\/p>\n