{"id":60221,"date":"2024-02-28T06:39:05","date_gmt":"2024-02-28T06:39:05","guid":{"rendered":"https:\/\/medsname.com\/primaquine\/"},"modified":"2026-04-30T10:23:49","modified_gmt":"2026-04-30T10:23:49","slug":"primaquine","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/primaquine\/","title":{"rendered":"Primaquine"},"content":{"rendered":"

<\/p>\n

\n

\u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc<\/h3>\n

Primaquine<\/strong> \u542b\u6709 \u30d7\u30ea\u30de\u30ad\u30f3\u30ea\u30f3\u9178\u5869 15 mg\uff08\u5869\u57fa\u63db\u7b97\uff09<\/strong> \uff08Sanofi India\uff09\u3002\u3053\u308c\u306f\u3001\u5e83\u304f\u5728\u5eab\u3055\u308c\u3066\u3044\u308b\u552f\u4e00\u306e\u85ac\u5264\u3067\u3001 \u4e09\u65e5\u71b1\u30de\u30e9\u30ea\u30a2\uff08P. vivax\uff09\u304a\u3088\u3073\u5375\u5f62\u30de\u30e9\u30ea\u30a2\uff08P. ovale\uff09\u306b\u3088\u308b\u518d\u767a\u6027\u30de\u30e9\u30ea\u30a2\u306e\u6839\u6cbb\u7642\u6cd5<\/strong> \u2014 \u4f11\u7720\u4e2d\u306e \u30d2\u30d7\u30ce\u30be\u30a4\u30c8<\/em> \u809d\u7d30\u80de\u671f\u3092\u6b7b\u6ec5\u3055\u305b\u307e\u3059\u3002\u3053\u306e\u6bb5\u968e\u306f\u4ed6\u306e\u6297\u30de\u30e9\u30ea\u30a2\u85ac\u3067\u306f\u52b9\u679c\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u6a19\u6e96\u7684\u306a\u7528\u6cd5\uff1a 1\u65e530 mg\uff08\u5869\u57fa\u63db\u7b97\uff09\u309214\u65e5\u9593<\/strong> \u30af\u30ed\u30ed\u30ad\u30f3\u306e3\u65e5\u9593\u6295\u4e0e\u306b\u3088\u308a\u8840\u4e2d\u6bb5\u968e\u306e\u539f\u866b\u3092\u9664\u53bb\u3057\u305f\u5f8c\u306b\u3002\u307e\u305f\u3001\u6b21\u306e\u76ee\u7684\u306b\u3082\u4f7f\u7528\u3055\u308c\u307e\u3059\uff1a P. falciparum<\/em> \u30ac\u30e1\u30c8\u30b5\u30a4\u30c8\u9664\u53bb\uff08\u5358\u56de0.25 mg\/kg\u6295\u4e0e\u3001\u611f\u67d3\u4f1d\u64ad\u963b\u6b62\uff09\u304a\u3088\u3073\uff5e\u306e\u9078\u629e\u80a2\u3068\u3057\u3066 \u30cb\u30e5\u30fc\u30e2\u30b7\u30b9\u30c1\u30b9\u30fb\u30a4\u30ed\u30d9\u30c1\u30a4\uff08Pneumocystis jirovecii\uff09<\/em> \u30b9\u30eb\u30d5\u30a1\u7cfb\u30a2\u30ec\u30eb\u30ae\u30fc\u60a3\u8005\u306e\u80ba\u708e\uff08\u30af\u30ea\u30f3\u30c0\u30de\u30a4\u30b7\u30f3\u4f75\u7528\uff09\u3002 \u4f7f\u7528\u524d\u306eG6PD\u691c\u67fb\u304c\u5fc5\u9808<\/strong> \u2014 \u30d7\u30ea\u30de\u30ad\u30f3\u306fG6PD\u6b20\u640d\u75c7\u60a3\u8005\u306b\u91cd\u5ea6\u306e\u6eb6\u8840\u6027\u8ca7\u8840\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u6d88\u5316\u5668\u75c7\u72b6\u3092\u8efd\u6e1b\u3059\u308b\u305f\u3081\u3001\u98df\u4e8b\u3068\u3068\u3082\u306b\u670d\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n

\ud83c\udfed WHO-GMP\u8a8d\u8a3c\u30e1\u30fc\u30ab\u30fc<\/strong>  \u00b7  \ud83d\udce6 \u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305<\/strong>  \u00b7  \ud83c\udf0d \u5168\u4e16\u754c\u914d\u9001<\/strong>  \u00b7  \u2b50 1,400\u4ef6\u4ee5\u4e0a\u306e\u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a><\/strong><\/div>\n

\ud83d\udee1\ufe0f \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u5f53\u793e\u306e \u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u304a\u8377\u7269\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u3001EMS\u307e\u305f\u306fITPS\u30af\u30fc\u30ea\u30a8\u3067\u7121\u6599\u306e\u4ee3\u66ff\u54c1\u3092\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n

MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n

\u30d7\u30ea\u30de\u30ad\u30f3\u306fWHO-GMP\u8a8d\u8a3c\u88fd\u9020\u696d\u8005\u304b\u3089\u8abf\u9054\u3057\u3001\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305\u3067\u5168\u4e16\u754c\u914d\u9001\u3044\u305f\u3057\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306b\u306f\u3001\u5f53\u793e\u306e \u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/a> \u3001\u5f53\u793e\u306e 1,400\u4ef6\u4ee5\u4e0a\u306e\u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a>. \u3002\u5168\u4e16\u754c\u914d\u9001\u3001\u51e6\u65b9\u7b8b\u4e0d\u8981\u3002<\/p>\n

\u30d7\u30ea\u30de\u30ad\u30f3\u306b\u3064\u3044\u3066<\/h2>\n

\u30d7\u30ea\u30de\u30ad\u30f3\u306f\u3001Sanofi India\u304cWHO-GMP\u8a8d\u8a3c\u6761\u4ef6\u4e0b\u3067\u88fd\u9020\u3059\u308b\u30d7\u30ea\u30de\u30ad\u30f3\u30ea\u30f3\u9178\u5869\uff08\u5869\u57fa\uff0915 mg\u9320\u3067\u3059\u3002\u30d7\u30ea\u30de\u30ad\u30f3\u306f\u7b2c\u4e8c\u6b21\u4e16\u754c\u5927\u6226\u4e2d\u306b\u7c73\u8ecd\u306b\u3088\u3063\u3066\u521d\u3081\u3066\u958b\u767a\u3055\u308c\u305f8-\u30a2\u30df\u30ce\u30ad\u30ce\u30ea\u30f3\u7cfb\u85ac\u5264\u3067\u3001WHO\u5fc5\u9808\u533b\u85ac\u54c1\u30ea\u30b9\u30c8\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4f11\u7720\u72b6\u614b\u306e\u809d\u81d3\u5185\u4f11\u7720\u4f53\uff08\u30d2\u30d7\u30ce\u30be\u30a4\u30c8\uff09\u3092\u6bba\u6ec5\u3059\u308b\u552f\u4e00\u306e\u5e83\u304f\u5229\u7528\u53ef\u80fd\u306a\u85ac\u5264\u3067\u3042\u308a\u3001 P. vivax<\/em> KYC\uff08Know Your Customer\uff09 P. ovale<\/em> \u2014 \u30d7\u30ea\u30de\u30ad\u30f3\u306b\u3088\u308b\u6cbb\u7642\u3092\u884c\u308f\u306a\u3044\u3068\u3001\u3053\u308c\u3089\u306e\u539f\u866b\u306f\u3001\u8840\u6db2\u30b9\u30c6\u30fc\u30b8\u6cbb\u7642\u5f8c\u6570\u9031\u9593\u304b\u3089\u6570\u304b\u6708\u3067\u518d\u767a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u30d7\u30ea\u30de\u30ad\u30f3\u306e\u4f5c\u7528\u6a5f\u5e8f<\/h2>\n

\u30d7\u30ea\u30de\u30ad\u30f3\u306e\u6b63\u78ba\u306a\u5206\u5b50\u6a19\u7684\u306f\u5b8c\u5168\u306b\u306f\u89e3\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u6709\u529b\u306a\u4eee\u8aac\u3067\u306f\u3001CYP2D6\u306b\u3088\u308a\u751f\u6210\u3055\u308c\u308b\u4ee3\u8b1d\u7269\u306e\u4e00\u3064\u304c\u6d3b\u6027\u9178\u7d20\u7a2e\u3084\u30d5\u30ea\u30fc\u30e9\u30b8\u30ab\u30eb\u3092\u751f\u6210\u3057\u3001\u809d\u81d3\u5185\u4f11\u7720\u4f53\u306e\u539f\u866b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u819c\u306b\u640d\u50b7\u3092\u4e0e\u3048\u308b\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u540c\u3058\u9178\u5316\u5316\u5b66\u53cd\u5fdc\u306f\u3001G6PD\u6b20\u640d\u8d64\u8840\u7403\uff08\u9084\u5143\u578b\u30b0\u30eb\u30bf\u30c1\u30aa\u30f3\u304c\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u4e2d\u548c\u3059\u308b\u305f\u3081\u306b\u518d\u751f\u3067\u304d\u306a\u3044\u72b6\u614b\uff09\u306b\u3082\u30c0\u30e1\u30fc\u30b8\u3092\u4e0e\u3048\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u30d7\u30ea\u30de\u30ad\u30f3\u306e\u6297\u5bc4\u751f\u866b\u6d3b\u6027\u3068\u6eb6\u8840\u6bd2\u6027\u304c\u4e26\u884c\u3057\u3066\u8d77\u3053\u308b\u7406\u7531\u304c\u8aac\u660e\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u30d7\u30ea\u30de\u30ad\u30f3\u306f\u8840\u6db2\u30b9\u30c6\u30fc\u30b8\u306e\u539f\u866b\u306b\u5bfe\u3059\u308b\u6d3b\u6027\u306f\u5f31\u3044\u305f\u3081\u3001\u307e\u305a\u8840\u6db2\u30b9\u30c6\u30fc\u30b8\u3092\u9664\u53bb\u3059\u308b\u305f\u3081\u306b\u3001\u30af\u30ed\u30ed\u30ad\u30f3\uff08\u30af\u30ed\u30ed\u30ad\u30f3\u611f\u53d7\u6027\u306e\u4e09\u65e5\u71b1\u30de\u30e9\u30ea\u30a2\/\u5375\u5f62\u30de\u30e9\u30ea\u30a2\u5730\u57df\uff09\u307e\u305f\u306f\u30a2\u30eb\u30c6\u30df\u30b7\u30cb\u30f3\u4f75\u7528\u7642\u6cd5\u3068\u4f75\u7528\u3057\u307e\u3059\u3002\u30d7\u30ea\u30de\u30ad\u30f3\u5358\u72ec\u306f\u6025\u6027\u75c7\u5019\u6027\u30de\u30e9\u30ea\u30a2\u306e\u6cbb\u7642\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u9069\u5fdc\u75c7\u3068\u7528\u6cd5\u30fb\u7528\u91cf<\/h2>\n
\n\n\n\n\n\n\n\n\n\n\n
\u9069\u5fdc\u75c7<\/th>\n\u7528\u91cf\uff08mg\u5869\u57fa\uff09<\/th>\n\u5099\u8003<\/th>\n<\/tr>\n<\/thead>\n
P. vivax\uff0fP. ovale \u6839\u6cbb\u6cbb\u7642\uff08G6PD\u6b63\u5e38\uff09<\/td>\n1\u65e530 mg\uff08\u5869\u57fa\u63db\u7b97\uff09\u309214\u65e5\u9593<\/td>\n\u8840\u6db2\u30b9\u30c6\u30fc\u30b8\u306e\u30af\u30ed\u30ed\u30ad\u30f3\uff08\u307e\u305f\u306fACT\uff09\u6cbb\u7642\u5f8c\u3002\u516814\u65e5\u9593\u306e\u670d\u85ac\u9075\u5b88\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u2014\u2014\u65e9\u671f\u4e2d\u6b62\u304c\u518d\u767a\u306e\u6700\u3082\u4e00\u822c\u7684\u306a\u7406\u7531\u3067\u3059\u3002<\/td>\n<\/tr>\n
\u71b1\u5e2f\u30fb\u30aa\u30bb\u30a2\u30cb\u30a2\u682a\u306e\u4e09\u65e5\u71b1\u30de\u30e9\u30ea\u30a2\uff08Chesson-like\u3001\u518d\u767a\u50be\u5411\u304c\u9ad8\u3044\uff09<\/td>\n1\u65e530 mg\uff08\u5869\u57fa\uff09\u309214\u65e5\u9593\u3001\u5c02\u9580\u533b\u306e\u5224\u65ad\u306b\u3088\u308a21\u65e5\u9593\u306b\u5ef6\u9577\u3055\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/td>\n\u30af\u30ed\u30ed\u30ad\u30f3\u8010\u6027\u307e\u305f\u306f\u4f11\u7720\u4f53\u304c\u591a\u3044\u682a\u3067\u306f\u3001\u3088\u308a\u9ad8\u3044\u7d2f\u7a4d\u6295\u4e0e\u91cf\u304c\u5fc5\u8981\u3067\u3059\u3002<\/td>\n<\/tr>\n
\u4e09\u65e5\u71b1\u30de\u30e9\u30ea\u30a2\u6839\u6cbb\u6cbb\u7642\uff08G6PD\u4e2d\u7b49\u5ea6\u6b20\u640d\uff09<\/td>\n0.75 mg\/kg\u3092\u90311\u56de\u30018\u9031\u9593\u6295\u4e0e<\/td>\n\u5c02\u9580\u533b\u306b\u3088\u308b\u76e3\u7763\u4e0b\u3067\u884c\u3044\u307e\u3059\u3002\u8840\u6db2\u5b66\u7684\u306a\u7d4c\u904e\u89b3\u5bdf\u304c\u5fc5\u8981\u3067\u3059\u3002<\/td>\n<\/tr>\n
\u71b1\u5e2f\u71b1\u30de\u30e9\u30ea\u30a2\u751f\u6b96\u6bcd\u4f53\u9664\u53bb\uff08\u4f1d\u64ad\u963b\u6b62\u3001WHO\u4f4e\u7528\u91cf\uff09<\/td>\nACT\u3068\u306e\u4f75\u7528\u30670.25 mg\/kg\u3092\u5358\u56de\u6295\u4e0e<\/td>\nG6PD\u6b20\u640d\u60a3\u8005\u306b\u304a\u3044\u3066\u3082\u3001\u3053\u306e\u5358\u56de\u6295\u4e0e\u3067\u306e\u6eb6\u8840\u30ea\u30b9\u30af\u306f\u4f4e\u3044\u3067\u3059\u3002<\/td>\n<\/tr>\n
\u30cb\u30e5\u30fc\u30e2\u30b7\u30b9\u30c1\u30b9\u80ba\u708e\uff08PJP\uff09\u2014 \u30b5\u30eb\u30d5\u30a1\u30a2\u30ec\u30eb\u30ae\u30fc\u306e\u5834\u5408\u306eTMP-SMX\u306e\u4ee3\u66ff<\/td>\n1\u65e530 mg\uff08\u5869\u57fa\uff09\u3068\u30af\u30ea\u30f3\u30c0\u30de\u30a4\u30b7\u30f3600 mg 1\u65e53\u56de\u7d4c\u53e3\u6295\u4e0e\u309221\u65e5\u9593<\/td>\nHIV\uff0f\u514d\u75ab\u4e0d\u5168\u5bbf\u4e3b\u306b\u304a\u3051\u308b\u5c02\u9580\u533b\u306e\u7ba1\u7406\u4e0b\u3067.<\/td>\n<\/tr>\n
\u5c0f\u5150\u4e09\u65e5\u71b1\u30de\u30e9\u30ea\u30a2\u6839\u6cbb\u7642\u6cd5\uff08\u751f\u5f8c6\u30f6\u6708\u4ee5\u4e0a\u3001G6PD\u6b63\u5e38\uff09<\/td>\n0.5 mg\/kg\/\u65e5\u309214\u65e5\u9593\uff08\u6700\u592730 mg\/\u65e5\uff09<\/td>\n\u9320\u5264\u306e\u5206\u5272\u304c\u5fc5\u8981\u306b\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
G6PD\u691c\u67fb\u306f\u5fc5\u9808 \u2014 \u4f7f\u7528\u524d\u306b\u5fc5\u305a\u5b9f\u65bd\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong> \u30d7\u30ea\u30de\u30ad\u30f3\u306fG6PD\u6b20\u640d\u60a3\u8005\u306b\u304a\u3044\u3066\u91cd\u5ea6\u306e\u6025\u6027\u6eb6\u8840\u6027\u8ca7\u8840\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002 \u51e6\u65b9\u524d\u306bG6PD\u6d3b\u6027\u3092\u691c\u67fb\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong>. \u6a19\u6e96\u7684\u306a\u86cd\u5149\u30b9\u30dd\u30c3\u30c8\u30c6\u30b9\u30c8\u307e\u305f\u306f\u5b9a\u91cf\u691c\u67fb\u304c\u4f7f\u7528\u53ef\u80fd\u3067\u3059\u3002 \u91cd\u5ea6\u306eG6PD\u6b20\u640d\u75c7\uff08\u6d3b\u602730%\u672a\u6e80\uff09<\/strong> \u2014 \u30d7\u30ea\u30de\u30ad\u30f3\u306f\u7981\u5fcc\uff1b\u30bf\u30d5\u30a7\u30ce\u30ad\u30f3\uff08\u7570\u306a\u308b8-\u30a2\u30df\u30ce\u30ad\u30ce\u30ea\u30f3\u3001\u5358\u56de\u6295\u4e0e\u3001\u540c\u3058\u304fG6PD\u5236\u9650\u3042\u308a\uff09\u307e\u305f\u306f\u4ee3\u66ff\u6226\u7565\u3092\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002 \u4e2d\u7b49\u5ea6\u306eG6PD\u6b20\u640d\u75c7\uff08\u30d8\u30c6\u30ed\u63a5\u5408\u4f53\u5973\u6027\u3001\u6d3b\u602730\uff5e70%\uff09<\/strong> \u2014 \u75c7\u4f8b\u3054\u3068\u306b\u5224\u65ad\u3057\u307e\u3059\u3002\u4e00\u90e8\u306e\u5c02\u9580\u5bb6\u306f\u3001\u8840\u6db2\u5185\u79d1\u306e\u76e3\u7763\u4e0b\u3067\u4fee\u6b63\u90311\u56de\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\uff080.75 mg\/kg\u3092\u90311\u56de\u00d78\u9031\u9593\uff09\u3092\u4f7f\u7528\u3057\u307e\u3059\u3002\u91cd\u5ea6\u306e\u6eb6\u8840\u306f\u3001\u6697\u8272\uff0f\u30b3\u30fc\u30e9\u8272\u306e\u5c3f\u3001\u9ec4\u75b8\u3001\u84bc\u767d\u3001\u75b2\u52b4\u3001\u547c\u5438\u56f0\u96e3\u3068\u3057\u3066\u73fe\u308c\u307e\u3059 \u2014 \u76f4\u3061\u306b\u85ac\u5264\u3092\u4e2d\u6b62\u3057\u3001\u533b\u5e2b\u306e\u8a3a\u5bdf\u3092\u53d7\u3051\u3066\u304f\u3060\u3055\u3044\u3002G6PD\u6b20\u640d\u75c7\u306e\u6709\u75c5\u7387\u306f\u3001\u30a2\u30d5\u30ea\u30ab\u3001\u5730\u4e2d\u6d77\u3001\u30a4\u30f3\u30c9\u3001\u4e2d\u6771\u3001\u6771\u5357\u30a2\u30b8\u30a2\u306e\u591a\u304f\u306e\u96c6\u56e3\u30675\uff5e10%\u3067\u3042\u308a\u3001\u4e00\u90e8\u306e\u4e9c\u96c6\u56e3\u3067\u306f\u3055\u3089\u306b\u9ad8\u304f\u306a\u308a\u307e\u3059\uff08\u30b5\u30eb\u30c7\u30fc\u30cb\u30e3\u4eba\u3084\u30af\u30eb\u30c9\u4eba\u7537\u6027\u3067\u306f\u6700\u592725%\uff09\u3002<\/div>\n

\u526f\u4f5c\u7528<\/h2>\n