{"id":60795,"date":"2024-02-28T07:08:53","date_gmt":"2024-02-28T07:08:53","guid":{"rendered":"https:\/\/medsname.com\/atrest\/"},"modified":"2026-05-01T10:49:16","modified_gmt":"2026-05-01T10:49:16","slug":"atrest","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/atrest\/","title":{"rendered":"Atrest"},"content":{"rendered":"

<\/p>\n

\n

\u26a1 \u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc \u2014 Atrest\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h3>\n

Atrest<\/strong> \u306f\u7d4c\u53e3 \u30c6\u30c8\u30e9\u30d9\u30ca\u30b8\u30f3<\/strong> (12.5 mg) \u9320 \u2014 a VMAT2\uff08\u5c0f\u80de\u30e2\u30ce\u30a2\u30df\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc2\uff09\u963b\u5bb3\u5264<\/strong> \u306e\u6cbb\u7642\u306b\u7279\u5316\u3057\u3066\u627f\u8a8d\u3055\u308c\u305f \u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u306b\u4f34\u3046\u821e\u8e0f\u904b\u52d5<\/strong>. \u795e\u7d4c\u7d42\u672b\u304b\u3089\u30c9\u30d1\u30df\u30f3\u3092\u67af\u6e07\u3055\u305b\u308b\u3053\u3068\u3067\u4f5c\u7528\u3057\u3001\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u821e\u8e0f\u75c5\u306b\u7279\u5fb4\u7684\u306a\u4e0d\u968f\u610f\u306e\u8eab\u3082\u3060\u3048\u3084\u3051\u3044\u308c\u3093\u69d8\u306e\u52d5\u304d\u3092\u8efd\u6e1b\u3057\u307e\u3059\u3002\u958b\u59cb\u7528\u91cf\uff1a 1\u65e51\u56de12.5mg<\/strong>, \u3001\u6bce\u903112.5 mg\u305a\u3064\u5897\u91cf\u3057\u3001\u6700\u5927 37.5 mg\/\u56de\uff0875\uff5e100 mg\/\u65e5\uff09<\/strong>, \u3001\u5fc5\u305a2\uff5e3\u56de\u306b\u5206\u5272\u6295\u4e0e\u3057\u307e\u3059\u30021\u65e550 mg\u8d85\u3092\u6295\u4e0e\u3055\u308c\u308b\u60a3\u8005\u306f CYP2D6\u907a\u4f1d\u5b50\u578b\u691c\u67fb<\/strong>. \u3002\u4e00\u822c\u7684\u306a\u526f\u4f5c\u7528\uff1a\u7720\u6c17\u3001\u30a2\u30ab\u30b7\u30b8\u30a2\u3001\u6291\u3046\u3064\u3001\u30d1\u30fc\u30ad\u30f3\u30bd\u30f3\u75c7\u5019\u7fa4\u3001\u4e0d\u7720\u75c7\u3002 \u9ed2\u67a0\u8b66\u544a\uff1a<\/strong> \u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u60a3\u8005\u306b\u304a\u3044\u3066\u3046\u3064\u75c5\u304a\u3088\u3073\u81ea\u6bba\u5ff5\u616e\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b \u2014 \u6c17\u5206\u3092\u6ce8\u610f\u6df1\u304f\u76e3\u8996\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n

\nMedsBase\u3067\u5f97\u3089\u308c\u308b\u3082\u306e\uff1a<\/strong> WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143 \u00b7 \u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305 \u00b7 \u5168\u4e16\u754c\u914d\u9001 \u00b7 1,400\u4ef6\u4ee5\u4e0a\u306e\u78ba\u8a8d\u6e08\u307f \u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a>\n<\/div>\n

\ud83d\udce6 \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u3001\u5f53\u5e97\u306e \u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u5546\u54c1\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u306f\u3001\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n

MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n

\u5f53\u5e97\u306e\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306f\u3001WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4ed5\u5165\u308c\u3001\u5168\u4e16\u754c\u3078\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u7121\u5730\u306e\u68b1\u5305\u3067\u767a\u9001\u3055\u308c\u307e\u3059\u3002\u914d\u9001\u7bb1\u306e\u5916\u5074\u306b\u306f\u533b\u85ac\u54c1\u540d\u306f\u4e00\u5207\u8a18\u8f09\u3055\u308c\u307e\u305b\u3093\u3002\u30ab\u30fc\u30c9\u6c7a\u6e08\u306f\u3001\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u3092\u7d4c\u7531\u3057\u3066\u51e6\u7406\u3055\u308c\uff08\u660e\u7d30\u66f8\u306e\u8868\u793a\u306b\u306f\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u306e\u307f\u304c\u8a18\u8f09\u3055\u308c\u3001\u300cMedsBase\u300d\u3084\u533b\u85ac\u54c1\u540d\u304c\u8868\u793a\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\uff09\u3001\u6697\u53f7\u8cc7\u7523\u3084SEPA\u9280\u884c\u632f\u8fbc\u3082\u3054\u5229\u7528\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306b\u306f\u3001\u5f53\u5e97\u306e\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc\u304c\u9069\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n

Atrest\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h2>\n

Atrest\u306f\u3001\u6709\u52b9\u6210\u5206\u3068\u3057\u3066 \u30c6\u30c8\u30e9\u30d9\u30ca\u30b8\u30f312.5mg<\/strong>. \u3002\u30c6\u30c8\u30e9\u30d9\u30ca\u30b8\u30f3\u306f\u3001 \u5c0f\u80de\u30e2\u30ce\u30a2\u30df\u30f3\u30c8\u30e9\u30f3\u30b9\u30dd\u30fc\u30bf\u30fc2\uff08VMAT2\uff09\u963b\u5bb3\u85ac<\/strong> \u2014 \u2026\u306e\u6cbb\u7642\u306b\u7279\u7570\u7684\u306b\u627f\u8a8d\u3055\u308c\u305f\u521d\u3081\u3066\u306e\u85ac\u5264 \u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u306b\u4f34\u3046\u821e\u8e0f\u904b\u52d5<\/strong>.<\/p>\n

\u30c6\u30c8\u30e9\u30d9\u30ca\u30b8\u30f3\u306f\u3001\u30b7\u30ca\u30d7\u30b9\u524d\u30c9\u30d1\u30df\u30f3\u8caf\u8535\u3092\u67af\u6e07\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u306b\u7279\u5fb4\u7684\u306a\u4e0d\u968f\u610f\u306e\u821e\u8e0f\u69d8\u904b\u52d5\uff08\u821e\u8e0f\u904b\u52d5\uff09\u3092\u8efd\u6e1b\u3057\u3001\u5f93\u6765\u306e\u30c9\u30d1\u30df\u30f3\u53d7\u5bb9\u4f53\u906e\u65ad\u85ac\u306e\u3088\u3046\u306a\u9045\u767a\u6027\u30b8\u30b9\u30ad\u30cd\u30b8\u30a2\u306e\u30ea\u30b9\u30af\u3092\u4f34\u3044\u307e\u305b\u3093\u30021970\u5e74\u4ee3\u306b\u6b27\u5dde\u3067\u521d\u3081\u3066\u4f7f\u7528\u3055\u308c\u30012008\u5e74\u306b\u306f Xenazine<\/strong>. \u3002Atrest\u306fWHO-GMP\u8a8d\u8a3c\u65bd\u8a2d\u3067\u88fd\u9020\u3055\u308c\u3001\u540c\u4e00\u7528\u91cf\u306b\u304a\u3044\u3066\u5148\u767a\u30d6\u30e9\u30f3\u30c9\u3068\u751f\u7269\u5b66\u7684\u306b\u540c\u7b49\u3067\u3059\u3002<\/p>\n

Atrest\uff08\u30c6\u30c8\u30e9\u30d9\u30ca\u30b8\u30f3\uff09\u306f\u3069\u306e\u3088\u3046\u306b\u4f5c\u7528\u3057\u307e\u3059\u304b\uff1f<\/h2>\n

\u30c6\u30c8\u30e9\u30d9\u30ca\u30b8\u30f3\u306f\u3001\u4e0d\u53ef\u9006\u7684\u306b VMAT2<\/strong>, \uff08\u30c9\u30d1\u30df\u30f3\u3001\u30bb\u30ed\u30c8\u30cb\u30f3\u3001\u30ce\u30eb\u30a8\u30d4\u30cd\u30d5\u30ea\u30f3\u3092\u30b7\u30ca\u30d7\u30b9\u5c0f\u80de\u306b\u53d6\u308a\u8fbc\u3080\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u3092\u963b\u5bb3\u3057\u307e\u3059\u3002VMAT2\u3092\u906e\u65ad\u3059\u308b\u3053\u3068\u3067\u3001\u3053\u306e\u85ac\u5264\u306f\u30b7\u30ca\u30d7\u30b9\u524d\u30e2\u30ce\u30a2\u30df\u30f3\u8caf\u8535\u3092\u67af\u6e07\u3055\u305b\u3001\u7279\u306b\u5927\u8133\u57fa\u5e95\u6838\u3067\u306f\u30c9\u30d1\u30df\u30f3\u304c\u4e2d\u5fc3\u3068\u306a\u308a\u307e\u3059\u3002\u7dda\u6761\u4f53\u306b\u304a\u3051\u308b\u904e\u5270\u306a\u30c9\u30d1\u30df\u30f3\u4f5c\u52d5\u6027\u6d3b\u52d5\u304c\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u306e\u821e\u8e0f\u904b\u52d5\u306e\u4e3b\u306a\u539f\u56e0\u3067\u3042\u308b\u305f\u3081\u3001\u30b7\u30ca\u30d7\u30b9\u5f8c\u53d7\u5bb9\u4f53\u3067\u306e\u30c9\u30d1\u30df\u30f3\u306e\u5229\u7528\u53ef\u80fd\u6027\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3053\u3068\u3067\u821e\u8e0f\u904b\u52d5\u304c\u76f4\u63a5\u6291\u5236\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u85ac\u5264\u306fCYP2D6\u306b\u3088\u3063\u3066\u5e83\u7bc4\u306b\u4ee3\u8b1d\u3055\u308c\u30012\u3064\u306e\u6d3b\u6027\u4ee3\u8b1d\u7269\uff08\u03b1-HTBZ\u304a\u3088\u3073\u03b2-HTBZ\uff09\u3092\u751f\u6210\u3057\u3001\u3053\u308c\u3089\u304c\u81e8\u5e8a\u52b9\u679c\u306e\u5927\u90e8\u5206\u3092\u62c5\u3063\u3066\u3044\u307e\u3059\u3002 CYP2D6\u4f4e\u4ee3\u8b1d\u80fd\u8005<\/strong> \u306f\u8840\u6f3f\u4e2d\u6fc3\u5ea6\u304c\u6709\u610f\u306b\u9ad8\u304f\u306a\u308b\u305f\u3081\u300150 mg\/\u65e5\u3092\u8d85\u3048\u308b\u524d\u306b\u907a\u4f1d\u5b50\u578b\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

\u7528\u6cd5\u30fb\u7528\u91cf<\/h2>\n\n\n\n\n\n\n\n\n
\u9031<\/th>\n1\u65e5\u306e\u7528\u91cf<\/th>\n\u6295\u4e0e\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb<\/th>\n<\/tr>\n<\/thead>\n
\u7b2c1\u9031<\/td>\n12.5 mg<\/td>\n1\u65e51\u56de\uff08\u671d\uff09<\/td>\n<\/tr>\n
\u7b2c2\u9031<\/td>\n25 mg<\/td>\n12.5 mg 1\u65e52\u56de<\/td>\n<\/tr>\n
3\u9031\u76ee\u4ee5\u964d<\/td>\n37.5\uff5e50 mg<\/td>\n2\uff5e3\u56de\u306b\u5206\u3051\u3066\u670d\u7528<\/td>\n<\/tr>\n
\u6700\u5927<\/td>\n75\uff5e100 mg\/\u65e5*<\/td>\n*50 mg\/\u65e5\u3092\u8d85\u3048\u308b\u5834\u5408\u306fCYP2D6\u907a\u4f1d\u5b50\u578b\u691c\u67fb\u304c\u5fc5\u8981<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u98df\u4e8b\u306e\u6709\u7121\u306b\u304b\u304b\u308f\u3089\u305a\u670d\u7528\u3067\u304d\u307e\u3059\u3002 1\u56de\u306e\u7528\u91cf\u306f37.5 mg\u3092\u8d85\u3048\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/strong> \u6cbb\u7642\u304c5\u65e5\u4ee5\u4e0a\u4e2d\u65ad\u3055\u308c\u305f\u5834\u5408\u306f\u300112.5 mg\u304b\u3089\u518d\u6f38\u5897\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n

\u526f\u4f5c\u7528<\/h2>\n
\u26a0 \u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a \u2014 \u3046\u3064\u75c5\u3068\u81ea\u6bba\u5ff5\u616e\uff1a<\/strong> \u30c6\u30c8\u30e9\u30d9\u30ca\u30b8\u30f3\u306f\u3001\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u60a3\u8005\u306b\u304a\u3044\u3066\u3046\u3064\u75c5\u304a\u3088\u3073\u81ea\u6bba\u5ff5\u616e\u30fb\u81ea\u6bba\u884c\u52d5\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002\u73fe\u5728\u81ea\u6bba\u5ff5\u616e\u306e\u3042\u308b\u60a3\u8005\u3001\u307e\u305f\u306f\u672a\u6cbb\u7642\u3042\u308b\u3044\u306f\u6cbb\u7642\u4e0d\u5341\u5206\u306a\u3046\u3064\u75c5\u306e\u3042\u308b\u60a3\u8005\u306b\u306f\u4f7f\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u60a3\u8005\u304a\u3088\u3073\u4ecb\u8b77\u8005\u306f\u3001\u65b0\u305f\u306a\u3046\u3064\u75c5\u3084\u305d\u306e\u60aa\u5316\u3001\u81ea\u6bba\u5ff5\u616e\u3001\u307e\u305f\u306f\u7570\u5e38\u306a\u884c\u52d5\u5909\u5316\u304c\u751f\u3058\u3066\u3044\u306a\u3044\u304b\u6ce8\u610f\u6df1\u304f\u89b3\u5bdf\u3059\u308b\u3088\u3046\u6307\u5c0e\u3055\u308c\u308b\u3079\u304d\u3067\u3059\u3002<\/div>\n

\u3088\u304f\u898b\u3089\u308c\u308b\uff0810\uff05\u4ee5\u4e0a\uff09\uff1a<\/strong> \u93ae\u9759\uff0f\u50be\u7720\u3001\u75b2\u52b4\u3001\u4e0d\u7720\u3001\u3046\u3064\u75c5\u3001\u30a2\u30ab\u30b7\u30b8\u30a2\uff08\u9759\u5750\u4e0d\u80fd\uff09\u3001\u4e0d\u5b89\u3001\u60aa\u5fc3\u3002<\/p>\n

\u91cd\u7be4\uff1a<\/strong> \u30d1\u30fc\u30ad\u30f3\u30bd\u30cb\u30ba\u30e0\uff08\u7528\u91cf\u4f9d\u5b58\u6027\uff09\u3001\u60aa\u6027\u75c7\u5019\u7fa4\uff08\u307e\u308c\uff09\u3001QTc\u5ef6\u9577\uff08\u5148\u5929\u6027QT\u5ef6\u9577\u75c7\u5019\u7fa4\u3067\u306f\u4f7f\u7528\u56de\u907f\uff09\u3001\u56a5\u4e0b\u969c\u5bb3\uff08\u30cf\u30f3\u30c1\u30f3\u30c8\u30f3\u75c5\u60a3\u8005\u3067\u306f\u8aa4\u56a5\u30ea\u30b9\u30af\u5897\u52a0\uff09\u3002<\/p>\n

\u8b66\u544a\u304a\u3088\u3073\u4f7f\u7528\u4e0a\u306e\u6ce8\u610f<\/h2>\n