{"id":66715,"date":"2025-05-01T14:00:13","date_gmt":"2025-05-01T14:00:13","guid":{"rendered":"https:\/\/medsbase.com\/?post_type=product&#038;p=66715"},"modified":"2026-04-30T10:23:27","modified_gmt":"2026-04-30T10:23:27","slug":"barinat","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/barinat\/","title":{"rendered":"Barinat"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">\u26a1 \u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc \u2014 Barinat\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h3>\n<p style=\"margin:0;\"><strong>Barinat<\/strong> \u306f\u3001Cipla\u793e\u306e\u7d4c\u53e3\u9320\u3067\u3001\u542b\u6709\u6210\u5206\u306f <strong>\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6<\/strong> \u2014 \u7d4c\u53e3 <strong>\u30e4\u30cc\u30b9\u30ad\u30ca\u30fc\u30bc\uff08JAK\uff09\u963b\u5bb3\u5264<\/strong> JAK1\u304a\u3088\u3073JAK2\u3092\u4ecb\u3057\u3066\u7d30\u80de\u5185\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u963b\u5bb3\u3057\u307e\u3059\u3002\u5165\u624b\u53ef\u80fd <strong>2mg\u304a\u3088\u30734mg<\/strong>. \u3002\u6a19\u6e96\u7528\u91cf\uff1a <strong>1\u65e51\u56de4mg\uff08\u4e2d\u7b49\u5ea6\u306e\u814e\u6a5f\u80fd\u969c\u5bb3\u307e\u305f\u306f\u611f\u67d3\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u60a3\u8005\u3067\u306f2mg\uff09<\/strong>. \u3002\u4f7f\u7528\u76ee\u7684\uff1a <strong>\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1<\/strong> \u304a\u3088\u3073\u3001\u5f93\u6765\u306eDMARDs\u304c\u7121\u52b9\u3068\u306a\u3063\u305f\u5f8c\u306e\u4ed6\u306e\u3044\u304f\u3064\u304b\u306e\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3002 <strong>FDA\u306e\u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a\u306e\u5bfe\u8c61\u3067\u3059<\/strong> \u91cd\u5ea6\u306e\u611f\u67d3\u75c7\u3001\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09\u3001\u8840\u6813\u75c7\u3001\u60aa\u6027\u816b\u760d \u2014 \u7279\u306b50\u6b73\u4ee5\u4e0a\u3067\u5c11\u306a\u304f\u3068\u30821\u3064\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u6301\u3064\u60a3\u8005\u306b\u304a\u3044\u3066\u3002 <strong>\u6cbb\u7642\u524d\u306e\u5fc5\u9808\u691c\u67fb\uff1a\u6f5c\u5728\u6027\u7d50\u6838\u3001B\u578b\u809d\u708e\u3001C\u578b\u809d\u708e\u3001\u8840\u7403\u5206\u753b\u3092\u542b\u3080\u5168\u8840\u7403\u7b97\u5b9a\uff08CBC\uff09\u3001\u809d\u6a5f\u80fd\u691c\u67fb\uff08LFTs\uff09\u3001\u8102\u8cea\u30d1\u30cd\u30eb\u3001\u304a\u3088\u3073\u6c34\u75d8\u5e2f\u72b6\u75b1\u75b9\u306e\u72b6\u614b\u3002<\/strong> \u7b2c\u4e00\u9078\u629e\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093 \u2014 \u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u307e\u305f\u306f\u751f\u7269\u5b66\u7684DMARDs\u3067\u52b9\u679c\u4e0d\u5341\u5206\u306a\u60a3\u8005\u306b\u9650\u3063\u3066\u4f7f\u7528\u3057\u307e\u3059\u3002<\/p>\n<\/div>\n<p><!-- medsbase-specialist-strip --><\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:0 0 24px 0;border-radius:4px;font-size:14px;\"><strong>\u2695 \u5c02\u9580\u533b\u306e\u76e3\u7763\u4e0b\u3067\u4f7f\u7528\u3059\u308b\u85ac \u2014 \u533b\u5e2b\u306e\u7ba1\u7406\u304c\u5fc5\u8981\u3067\u3059\u3002<\/strong> \u3053\u308c\u306f\u3001\u7279\u5b9a\u306e\u6cbb\u7642\u524d\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u8981\u4ef6\u3001\u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a\u3001\u304a\u3088\u3073\u5fc5\u9808\u306e\u81e8\u5e8a\u691c\u67fb\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3092\u4f34\u3046\u5f37\u529b\u306a\u514d\u75ab\u8abf\u7bc0\u85ac\u3067\u3059\u3002\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\u3001\u6d88\u5316\u5668\u75c5\u5c02\u9580\u533b\u3001\u76ae\u819a\u79d1\u5c02\u9580\u533b\u3001\u307e\u305f\u306f\u305d\u306e\u4f7f\u7528\u7d4c\u9a13\u306e\u3042\u308b\u305d\u306e\u4ed6\u306e\u5c02\u9580\u533b\u306b\u3088\u3063\u3066\u51e6\u65b9\u30fb\u76e3\u7763\u3055\u308c\u308b\u3079\u304d\u3067\u3059\u3002Do <strong>\u3057\u307e\u305b\u3093<\/strong> self-prescribe, self-adjust the dose, or start\/stop without a prescriber's direction. MedsBase\u3067\u3054\u6ce8\u6587\u524d\u306b\u3001\u5fc5\u305a\u4e3b\u6cbb\u533b\u306b\u73fe\u5728\u306e\u51e6\u65b9\u3092\u63d0\u793a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f6f8;border:1px solid #e1e4e8;border-radius:4px;padding:14px 18px;margin:18px 0;display:flex;flex-wrap:wrap;gap:14px;font-size:0.95em;\"><span>\u2705 <strong>WHO-GMP\u8a8d\u8a3c<\/strong> \u88fd\u9020\u5143<\/span><span>\ud83d\udce6 <strong>\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305<\/strong><\/span><span>\ud83c\udf0d <strong>\u5168\u4e16\u754c\u914d\u9001<\/strong><\/span><span>\ud83d\udcac <a href=\"\/ja\/reviews\/\">1,400\u4ef6\u4ee5\u4e0a\u306e\u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a><\/span><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u3001\u5f53\u5e97\u306e <a href=\"https:\/\/medsbase.com\/ja\/medsbase-re-shipment-assurance-policy\/\"><strong>\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u5546\u54c1\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u306f\u3001\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<h3>MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n<p>\u5f53\u5e97\u306e\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u533b\u85ac\u54c1\u306f\u3001WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4ed5\u5165\u308c\u3001\u5168\u4e16\u754c\u3078\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u7121\u5730\u306e\u68b1\u5305\u3067\u767a\u9001\u3055\u308c\u307e\u3059\u3002\u914d\u9001\u7bb1\u306e\u5916\u5074\u306b\u306f\u533b\u85ac\u54c1\u540d\u306f\u4e00\u5207\u8a18\u8f09\u3055\u308c\u307e\u305b\u3093\u3002\u30ab\u30fc\u30c9\u6c7a\u6e08\u306f\u3001\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u3092\u7d4c\u7531\u3057\u3066\u51e6\u7406\u3055\u308c\uff08\u660e\u7d30\u66f8\u306e\u8868\u793a\u306b\u306f\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u306e\u307f\u304c\u8a18\u8f09\u3055\u308c\u3001\u300cMedsBase\u300d\u3084\u533b\u85ac\u54c1\u540d\u304c\u8868\u793a\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\uff09\u3001\u6697\u53f7\u8cc7\u7523\u3084SEPA\u9280\u884c\u632f\u8fbc\u3082\u3054\u5229\u7528\u3044\u305f\u3060\u3051\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306b\u306f\u3001\u5f53\u5e97\u306e\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc\u304c\u9069\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<h2 class=\"wp-block-heading\">Barinat\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h2>\n<p>Barinat\u306f\u3001Cipla\u304c\u88fd\u9020\u3059\u308b\u7d4c\u53e3\u9320\u3067\u3001\u542b\u6709\u3059\u308b <strong>\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6<\/strong>, \u3001\u4f4e\u5206\u5b50 <strong>\u30e4\u30cc\u30b9\u30ad\u30ca\u30fc\u30bc\uff08JAK\uff09\u963b\u5bb3\u5264<\/strong>. \u3002JAK\u963b\u5bb3\u85ac\u306f\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u304c\u514d\u75ab\u7d30\u80de\u4e0a\u306e\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3059\u308b\u969b\u306b\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u7d30\u80de\u5185\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30ab\u30b9\u30b1\u30fc\u30c9\u3092\u906e\u65ad\u3059\u308b\u3001\u65b0\u3057\u3044\u30af\u30e9\u30b9\u306e\u6a19\u7684\u5408\u6210\u75be\u60a3\u4fee\u98fe\u6027\u6297\u30ea\u30a6\u30de\u30c1\u85ac\uff08tsDMARDs\uff09\u3067\u3059\u3002<\/p>\n<p>Barinat\u306f\u3001Cipla\u306e\u30b8\u30a7\u30cd\u30ea\u30c3\u30af\u306e\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6 \u2014 \u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306b\u5bfe\u3057\u3066\u6700\u521d\u306b\u627f\u8a8d\uff08Olumiant\u3001Lilly\u793e\uff09\u3055\u308c\u305f\u9078\u629e\u7684JAK1\/JAK2\u963b\u5bb3\u85ac\u3067\u3042\u308a\u3001\u305d\u306e\u5f8c\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\u3001\u91cd\u75c7\u5186\u5f62\u8131\u6bdb\u75c7\u3001\u304a\u3088\u3073\u5165\u9662\u3092\u8981\u3059\u308bCOVID-19\u306b\u3082\u9069\u5fdc\u304c\u62e1\u5927\u3055\u308c\u307e\u3057\u305f\u30021\u65e51\u56de\u306e\u6295\u4e0e\u3067\u3001\u5229\u7528\u53ef\u80fd\u306a\u6a19\u7684RA\u6cbb\u7642\u306e\u4e2d\u3067\u6700\u3082\u5229\u4fbf\u6027\u306e\u9ad8\u3044\u6cbb\u7642\u306e1\u3064\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u5f93\u6765\u306e\u6ce8\u5c04\u53ef\u80fd\u306a\u751f\u7269\u5b66\u7684\u88fd\u5264\uff08TNF\u963b\u5bb3\u85ac\u3001IL-6\u963b\u5bb3\u85ac\uff09\u3068\u306f\u7570\u306a\u308a\u3001\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306f\u9320\u5264\u3067\u670d\u7528\u3057\u3001\u52b9\u679c\u767a\u73fe\u304c\u901f\u304f\uff082\u301c4\u9031\u9593\u4ee5\u5185\u306b\u81e8\u5e8a\u7684\u306a\u6539\u5584\u304c\u898b\u3089\u308c\u307e\u3059\uff09\u3001\u7570\u306a\u308b\u5206\u5b50\u7d4c\u8def\u3067\u4f5c\u7528\u3059\u308b\u305f\u3081\u3001\u5f93\u6765\u306eDMARDs\u307e\u305f\u306f1\u7a2e\u985e\u4ee5\u4e0a\u306e\u751f\u7269\u5b66\u7684\u88fd\u5264\u3067\u52b9\u679c\u304c\u4e0d\u5341\u5206\u306a\u60a3\u8005\u306b\u3068\u3063\u3066\u6709\u7528\u306a\u9078\u629e\u80a2\u3068\u306a\u308a\u307e\u3059\u3002\u4e3b\u306a\u30a8\u30d3\u30c7\u30f3\u30b9\uff1aRA-BEAM\u304a\u3088\u3073RA-BEACON\uff08\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\uff09\u3001BREEZE-AD\uff08\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\uff09\u3001COV-BARRIER\uff08COVID-19\u5165\u9662\u60a3\u8005\uff09\u3002<\/p>\n<h2 class=\"wp-block-heading\">Barinat\u306f\u3069\u306e\u3088\u3046\u306b\u4f5c\u7528\u3057\u307e\u3059\u304b\uff1f<\/h2>\n<p>\u591a\u304f\u306e\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\uff08IL-6\u3001IFN-\u03b3\u3001GM-CSF\u3001IL-2\u3001IL-4\u3001IL-15\u3001IL-21\u306a\u3069\uff09\u306f\u3001\u7d30\u80de\u5185\u3067\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u884c\u3046\u969b\u306b\u3001 <strong>JAK-STAT\u7d4c\u8def<\/strong>. \u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u304c\u53d7\u5bb9\u4f53\u306b\u7d50\u5408\u3059\u308b\u3068\u3001JAK\u9175\u7d20\u304cSTAT\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30ea\u30f3\u9178\u5316\u3057\u3001\u305d\u308c\u304c\u6838\u5185\u3078\u79fb\u884c\u3057\u3066\u708e\u75c7\u3001T\u7d30\u80de\u6d3b\u6027\u5316\u3001\u6ed1\u819c\u5897\u6b96\u3092\u5f15\u304d\u8d77\u3053\u3059\u907a\u4f1d\u5b50\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u5165\u308c\u307e\u3059\u3002<\/p>\n<ul>\n<li><strong>\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306fJAK1\u3068JAK2\u3092\u963b\u5bb3\u3057<\/strong> \u7d30\u80de\u5185\u3067\u3001\u8907\u6570\u306e\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u540c\u6642\u306b\u906e\u65ad\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u306b\u5bfe\u3059\u308b\u5e83\u7bc4\u306a\u52b9\u679c<\/strong> \u2014 \u591a\u304f\u306e\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u53d7\u5bb9\u4f53\u304cJAK1\/JAK2\/JAK3\/TYK2\u3092\u69d8\u3005\u306a\u7d44\u307f\u5408\u308f\u305b\u3067\u5229\u7528\u3059\u308b\u305f\u3081\u3001\u5358\u4e00\u306eJAK\u963b\u5bb3\u85ac\u306f\u4e00\u5ea6\u306b\u591a\u304f\u306e\u708e\u75c7\u7d4c\u8def\u3092\u6291\u5236\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u901f\u3084\u304b\u306a\u81e8\u5e8a\u52b9\u679c\u304c\u5f97\u3089\u308c\u307e\u3059\u304c\u3001\u611f\u67d3\u75c7\u3084\u60aa\u6027\u816b\u760d\u306e\u30b7\u30b0\u30ca\u30eb\u304c\u751f\u3058\u308b\u7406\u7531\u3067\u3082\u3042\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u53ef\u9006\u7684\u306a\u963b\u5bb3<\/strong> \u2014 \u85ac\u306e\u670d\u7528\u3092\u4e2d\u6b62\u3059\u308b\u30681\uff5e2\u65e5\u4ee5\u5185\u306b\u52b9\u679c\u304c\u6d88\u5931\u3057\u307e\u3059\u3002\u624b\u8853\u524d\u3084\u611f\u67d3\u75c7\u7f79\u60a3\u6642\u306b\u6709\u7528\u3067\u3059\u3002<\/li>\n<\/ul>\n<p>\u75c7\u72b6\u6539\u5584\u306e\u958b\u59cb\u6642\u671f\uff1a\u95a2\u7bc0\u75db\u306e\u6539\u5584\u306f\u3001 <strong>2\uff5e4\u9031\u9593<\/strong>; \uff1b\u81e8\u5e8a\u7684\u53cd\u5fdc\u306e\u30d4\u30fc\u30af\u306f3\uff5e6\u304b\u6708\u5f8c\u3067\u3059\u3002\u95a2\u7bc0\u7834\u58ca\u306e\u9032\u884c\u6291\u5236\u304c\u753b\u50cf\u3067\u78ba\u8a8d\u3067\u304d\u308b\u307e\u3067\u306b\u306f\u300112\u304b\u6708\u9593\u306e\u7d99\u7d9a\u670d\u7528\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p>\n<h2 class=\"wp-block-heading\">\u4f7f\u7528\u76ee\u7684\u3068\u9069\u5fdc\u75c7<\/h2>\n<ul>\n<li><strong>\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1<\/strong> \u2014 1\u7a2e\u985e\u4ee5\u4e0a\u306eDMARD\uff08\u901a\u5e38\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\uff09\u3067\u52b9\u679c\u4e0d\u5341\u5206\u306a\u5834\u5408<\/li>\n<li><strong>\u91cd\u5ea6\u306e\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\uff08\u6e7f\u75b9\uff09<\/strong> \u6210\u4eba\u304a\u3088\u3073\u9752\u5c11\u5e74\u306b\u304a\u3044\u3066<\/li>\n<li><strong>\u91cd\u5ea6\u306e\u5186\u5f62\u8131\u6bdb\u75c7<\/strong> \u6210\u4eba\u306b\u304a\u3044\u3066<\/li>\n<li><strong>\u5165\u9662\u3092\u8981\u3059\u308bCOVID-19<\/strong> \u9178\u7d20\u5438\u5165\u3092\u5fc5\u8981\u3068\u3059\u308b\u5834\u5408\uff08FDA\u7dca\u6025\u4f7f\u7528\u8a31\u53ef\uff1b2024\u5e74\u6642\u70b9\u3067\u306f\u6a19\u6e96\u6cbb\u7642\u306b\u307b\u307c\u7f6e\u304d\u63db\u3048\u3089\u308c\u3066\u3044\u307e\u3059\uff09<\/li>\n<\/ul>\n<p>Barinat\u306f <strong>\u3057\u307e\u305b\u3093<\/strong> \u3053\u308c\u3089\u306e\u3044\u305a\u308c\u304b\u306e\u75be\u60a3\u306b\u5bfe\u3059\u308b\u7b2c\u4e00\u9078\u629e\u85ac\u3067\u3059\u3002\u672c\u5264\u306f <strong>\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8<\/strong> \u304c\u7121\u52b9\u307e\u305f\u306f\u5fcd\u5bb9\u3067\u304d\u306a\u3044\u60a3\u8005\u306b\u9650\u308a\u4f7f\u7528\u3055\u308c\u3001\u73fe\u884c\u306eFDA\u30ac\u30a4\u30c0\u30f3\u30b9\u306b\u5f93\u3048\u3070\u3001\u7406\u60f3\u7684\u306b\u306f <strong>TNF\u963b\u5bb3\u85ac<\/strong> \u306b\u3088\u308b\u6cbb\u7642\u3092\u7d4c\u305f\u5f8c\u306bJAK\u963b\u5bb3\u85ac\u306e\u6295\u4e0e\u3092\u958b\u59cb\u3057\u307e\u3059\u3002\u7279\u306b\u300150\u6b73\u4ee5\u4e0a\u3067\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\u30921\u3064\u4ee5\u4e0a\u6709\u3059\u308b\u60a3\u8005\u3067\u306f\u3001ORAL Surveillance\u8a66\u9a13\u306b\u304a\u3044\u3066TNF\u963b\u5bb3\u85ac\u3068\u6bd4\u8f03\u3057\u3066\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09\u304a\u3088\u3073\u60aa\u6027\u816b\u760d\u306e\u767a\u73fe\u7387\u304c\u9ad8\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h2 class=\"wp-block-heading\">Barinat\u958b\u59cb\u524d\u306e\u5fc5\u9808\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb<\/h2>\n<p>\u3059\u3079\u3066\u306e\u60a3\u8005\u306f\u3001\u521d\u56de\u6295\u4e0e\u524d\u306b\u4ee5\u4e0b\u306e\u691c\u67fb\u3092\u5b8c\u4e86\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u3092\u7701\u7565\u3059\u308b\u3053\u3068\u304c\u3001JAK\u963b\u5bb3\u85ac\u306b\u3088\u308b\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306e\u6700\u3082\u4e00\u822c\u7684\u306a\u539f\u56e0\u3067\u3059\u3002<\/p>\n<ul>\n<li><strong>\u6f5c\u5728\u6027\u7d50\u6838\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0<\/strong> \u2014 \u30af\u30a9\u30f3\u30c6\u30a3\u30d5\u30a7\u30ed\u30f3TB\u30b4\u30fc\u30eb\u30c9\u307e\u305f\u306fT-SPOT\uff08\u63a8\u5968\uff09\u3001\u3082\u3057\u304f\u306f\u30c4\u30d9\u30eb\u30af\u30ea\u30f3\u53cd\u5fdc\u691c\u67fb\u3002JAK\u963b\u5bb3\u306b\u3088\u308a\u3001\u7d041\uff05\u306e\u60a3\u8005\u3067\u6f5c\u4f0f\u7d50\u6838\u304c\u518d\u6d3b\u6027\u5316\u3057\u307e\u3059\u3002\u967d\u6027\u306e\u5834\u5408\u306f\u3001\u672c\u5264\u958b\u59cb\u524d\u306b\u5c11\u306a\u304f\u3068\u30821\u304b\u6708\u9593\u306e\u30a4\u30bd\u30cb\u30a2\u30b8\u30c9\uff08\u307e\u305f\u306f\u540c\u7b49\u85ac\uff09\u306b\u3088\u308b\u6cbb\u7642\u3092\u5b8c\u4e86\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>B\u578b\u809d\u708e<\/strong> \u2014 HBs\u6297\u539f\u3001HBc\u6297\u4f53\u3001HBs\u6297\u4f53\u3002\u6162\u6027B\u578b\u809d\u708e\u304c\u967d\u6027\u306e\u5834\u5408\u306f\u3001\u809d\u81d3\u5c02\u9580\u533b\u306e\u8a3a\u5bdf\u3068\u3001JAK\u963b\u5bb3\u85ac\u6295\u4e0e\u671f\u9593\u4e2d\u306e\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\uff08\u30a8\u30f3\u30c6\u30ab\u30d3\u30eb\u307e\u305f\u306f\u30c6\u30ce\u30db\u30d3\u30eb\uff09\u306b\u3088\u308b\u4e88\u9632\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>C\u578b\u809d\u708e<\/strong> \u2014 HCV\u6297\u4f53\u3001\u967d\u6027\u306e\u5834\u5408\u306fHCV RNA\u3067\u78ba\u8a8d\u3002C\u578b\u809d\u708e\u304c\u5b58\u5728\u3059\u308b\u5834\u5408\u306f\u3001\u307e\u305a\u305d\u306e\u6cbb\u7642\u3092\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>HIV\u611f\u67d3\u72b6\u6cc1<\/strong> \u2014 \u7d76\u5bfe\u7684\u306a\u7981\u5fcc\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u5c02\u9580\u533b\u306e\u5224\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u5206\u753b\u3092\u542b\u3080\u5168\u8840\u7403\u8a08\u7b97<\/strong> \u2014 \u597d\u4e2d\u7403\u7d76\u5bfe\u6570\u304c1.0\u00d710\u2079\/L\u672a\u6e80\u3001\u30ea\u30f3\u30d1\u7403\u7d76\u5bfe\u6570\u304c0.5\u00d710\u2079\/L\u672a\u6e80\u3001\u307e\u305f\u306f\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u304c9 g\/dL\u672a\u6e80\u306e\u5834\u5408\u306f\u958b\u59cb\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u809d\u6a5f\u80fd<\/strong> \u2014 ALT\/AST\u304c\u6b63\u5e38\u4e0a\u9650\u306e3\u500d\u3092\u8d85\u3048\u308b\u5834\u5408\u306f\u958b\u59cb\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u814e\u6a5f\u80fd<\/strong> \u2014 eGFR\u306b\u5fdc\u3058\u3066\u7528\u91cf\u3092\u6c7a\u5b9a\u3057\u307e\u3059\uff08\u7528\u6cd5\u30fb\u7528\u91cf\u306e\u9805\u76ee\u3092\u53c2\u7167\uff09\u3002<\/li>\n<li><strong>\u8102\u8cea\u30d1\u30cd\u30eb<\/strong> \u2014 \u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u306e\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3001LDL\u3001HDL\u3001\u30c8\u30ea\u30b0\u30ea\u30bb\u30ea\u30c9\u3002JAK\u963b\u5bb3\u85ac\u306f\u8102\u8cea\u3092\u4e0a\u6607\u3055\u305b\u307e\u3059\u30028\u9031\u5f8c\u304a\u3088\u3073\u305d\u306e\u5f8c\u306f\u5e741\u56de\u518d\u691c\u67fb\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u598a\u5a20\u691c\u67fb\u85ac<\/strong> \u598a\u5a20\u53ef\u80fd\u306a\u5973\u6027\u306e\u5834\u5408\u3002\u6cbb\u7642\u4e2d\u304a\u3088\u3073\u6700\u7d42\u6295\u4e0e\u5f8c\u7d041\u9031\u9593\u306f\u3001\u52b9\u679c\u7684\u306a\u907f\u598a\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u6c34\u75d8\u30fb\u5e2f\u72b6\u75b1\u75b9\u30a6\u30a4\u30eb\u30b9\u306e\u6297\u4f53\u4fdd\u6709\u72b6\u6cc1<\/strong> \u2014 \u6c34\u75d8\u306e\u65e2\u5f80\u6b74\u307e\u305f\u306fVZV\u8840\u6e05\u691c\u67fb\u3002\u8840\u6e05\u9670\u6027\u306e\u5834\u5408\u306f\u3001JAK\u963b\u5bb3\u85ac\u306b\u3088\u308b\u6cbb\u7642\u3092\u958b\u59cb\u3059\u308b\u5c11\u306a\u304f\u3068\u30824\u9031\u9593\u524d\u306b\u6c34\u75d8\u30ef\u30af\u30c1\u30f3\u3092\u63a5\u7a2e\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306e\u78ba\u8a8d<\/strong> \u2014 \u4ee5\u4e0b\u3092\u3059\u3079\u3066\u6700\u65b0\u306e\u72b6\u614b\u306b\u3059\u308b <em>\u4e0d\u6d3b\u5316<\/em> \u30ef\u30af\u30c1\u30f3\uff08\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3001\u80ba\u708e\u7403\u83cc\u3001COVID-19\u3001HPV\u3001\u5e2f\u72b6\u75b1\u75b9\uff08\u7d44\u63db\u3048\u4e0d\u6d3b\u5316\u30ef\u30af\u30c1\u30f3\uff1aShingrix\uff09\uff09\u3002 <strong>\u6cbb\u7642\u4e2d\u306f\u751f\u30ef\u30af\u30c1\u30f3\u306e\u63a5\u7a2e\u306f\u7981\u5fcc\u3067\u3059\u3002<\/strong> \u2014 \u6cbb\u7642\u958b\u59cb\u306e\u5c11\u306a\u304f\u3068\u30824\u9031\u9593\u524d\u306b\u63a5\u7a2e\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Barinat\u306e\u7528\u6cd5\u30fb\u7528\u91cf\u3068\u670d\u7528\u65b9\u6cd5<\/h2>\n<p>Barinat\u306e\u898f\u683c\uff1a <strong>2mg\u304a\u3088\u30734mg<\/strong>. \u3002\u7528\u91cf\u306f\u3001\u9069\u5fdc\u75c7\u3001\u814e\u6a5f\u80fd\u3001\u4f75\u7528\u85ac\u306b\u5fdc\u3058\u3066\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n<ul>\n<li><strong>\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3001\u30a2\u30c8\u30d4\u30fc\u6027\u76ae\u819a\u708e\uff1a<\/strong> 1\u65e51\u56de4mg\u3092\u670d\u7528\u3057\u3001\u6301\u7d9a\u7684\u306a\u5bdb\u89e3\u304c\u5f97\u3089\u308c\u305f\u5834\u5408\u3084\u611f\u67d3\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u60a3\u8005\u3067\u306f1\u65e51\u56de2mg\u306b\u6e1b\u91cf\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u5186\u5f62\u8131\u6bdb\u75c7\uff1a<\/strong> 1\u65e51\u56de4mg\u3092\u670d\u7528\u3057\u3001\u5341\u5206\u306a\u52b9\u679c\u304c\u5f97\u3089\u308c\u305f\u5f8c\u306b1\u65e51\u56de2mg\u306b\u6e1b\u91cf\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u814e\u6a5f\u80fd\u306b\u5fdc\u3058\u305f\u7528\u91cf\u8abf\u6574\uff1a<\/strong> eGFR 30\uff5e60mL\/\u5206 \u2192 1\u65e51\u56de\u6700\u59272mg\uff1beGFR 15\uff5e29mL\/\u5206 \u2192 1\u65e51\u56de1mg\uff08\u5c02\u9580\u533b\u306e\u307f\uff09\uff1beGFR 15mL\/\u5206\u672a\u6e80 \u2192 \u4f7f\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u809d\u6a5f\u80fd\u969c\u5bb3\uff1a<\/strong> \u8efd\u5ea6\u809d\u969c\u5bb3\u3067\u306f\u7528\u91cf\u8abf\u6574\u4e0d\u8981\uff1b\u91cd\u5ea6\uff08Child-Pugh C\uff09\u3067\u306f\u63a8\u5968\u3055\u308c\u307e\u305b\u3093\u3002<\/li>\n<li><strong>\u98df\u4e8b\u306e\u6709\u7121\u306b\u95a2\u308f\u3089\u305a\uff1a<\/strong> \u98df\u4e8b\u3068\u4e00\u7dd2\u306b\u3001\u307e\u305f\u306f\u7a7a\u8179\u6642\u306b\u670d\u7528\u3067\u304d\u307e\u3059\u3002\u6bce\u65e5\u540c\u3058\u6642\u9593\u306b\u670d\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<\/ul>\n<h3 class=\"wp-block-heading\">Barinat\uff08\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\uff09\u306e\u6b63\u3057\u3044\u670d\u7528\u65b9\u6cd5<\/h3>\n<ol>\n<li><strong>\u4e0a\u8a18\u306e\u6cbb\u7642\u524d\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u691c\u67fb\u3092\u5b9f\u65bd\u305b\u305a\u306b\u670d\u7528\u3092\u958b\u59cb\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/strong> \u5fc5\u8981\u306a\u691c\u67fb\u30921\u3064\u6020\u308b\u305f\u3073\u306b\u3001\u91cd\u7be4\u306a\u4e8b\u8c61\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u9320\u5264\u306f\u6c34\u3068\u3068\u3082\u306b\u4e38\u3054\u3068\u98f2\u307f\u8fbc\u3093\u3067\u304f\u3060\u3055\u3044\u3002<\/strong> \u2014 \u7815\u3044\u305f\u308a\u3001\u5206\u5272\u3057\u305f\u308a\u3001\u565b\u3093\u3060\u308a\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u9320\u306f\u30d5\u30a3\u30eb\u30e0\u30b3\u30fc\u30c6\u30a3\u30f3\u30b0\u9320\u3067\u3059\u3002<\/li>\n<li><strong>\u6bce\u65e5\u540c\u3058\u6642\u9593\u306b\u3002<\/strong> \u98df\u4e8b\u306e\u30bf\u30a4\u30df\u30f3\u30b0\u3088\u308a\u3082\u3001\u898f\u5247\u6b63\u3057\u304f\u670d\u7528\u3059\u308b\u3053\u3068\u306e\u307b\u3046\u304c\u91cd\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u70b9\u773c\u3092\u5fd8\u308c\u305f\u5834\u5408<\/strong>, \u3001\u5f53\u65e5\u4e2d\u306b\u601d\u3044\u51fa\u3057\u305f\u6642\u70b9\u3067\u76f4\u3061\u306b\u670d\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u6b21\u306e\u670d\u7528\u4e88\u5b9a\u6642\u523b\u304c\u8feb\u3063\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u98f2\u307f\u5fd8\u308c\u305f\u5206\u306f\u98db\u3070\u3057\u3066\u30012\u56de\u5206\u3092\u4e00\u5ea6\u306b\u670d\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u611f\u67d3\u75c7\u4e2d\u306f\u4f11\u85ac<\/strong> \u2014 \u91cd\u7be4\u306a\u611f\u67d3\u75c7\u306e\u6700\u521d\u306e\u5146\u5019\uff08\u9ad8\u71b1\u3001\u6e7f\u6027\u54b3\u55fd\u3001\u814e\u76c2\u814e\u708e\u3001\u8702\u7aa9\u7e54\u708e\u3001\u5e2f\u72b6\u75b1\u75b9\uff09\u304c\u73fe\u308c\u305f\u3089Barinat\u3092\u4e2d\u6b62\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u611f\u67d3\u75c7\u304c\u6cbb\u7652\u3057\u3001\u51e6\u65b9\u533b\u304c\u518d\u958b\u3092\u5224\u65ad\u3057\u305f\u5f8c\u306b\u306e\u307f\u670d\u7528\u3092\u518d\u958b\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u4e88\u5b9a\u624b\u8853\u306e\u524d\u306f\u4f11\u85ac\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong> \u5927\u624b\u8853\u306e1\u9031\u9593\u524d\u304b\u3089\u4f11\u85ac\u3057\u3001\u5275\u50b7\u6cbb\u7652\u304c\u9032\u307f\u611f\u67d3\u306e\u306a\u3044\u3053\u3068\u3092\u78ba\u8a8d\u3057\u3066\u304b\u30891\uff5e2\u9031\u9593\u5f8c\u306b\u518d\u958b\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u7d99\u7d9a\u7684\u306a\u81e8\u5e8a\u691c\u67fb\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0<\/strong> \u2014 CBC\uff08\u5168\u8840\u7403\u8a08\u7b97\uff09\u3068LFT\uff08\u809d\u6a5f\u80fd\u691c\u67fb\uff09\u3092 <strong>4\u9031\u76ee\u30018\u9031\u76ee\u300112\u9031\u76ee<\/strong>, \u3001\u305d\u306e\u5f8c3\u304b\u6708\u3054\u3068\u3002 \u8102\u8cea\u30d1\u30cd\u30eb\u691c\u67fb\u3092 <strong>8\u9031\u76ee<\/strong>, \u3001\u305d\u306e\u5f8c\u306f\u6bce\u5e74\u3002\u3053\u308c\u3089\u306e\u691c\u67fb\u3092\u9003\u3055\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u65b0\u305f\u306a\u54b3\u3001\u767a\u71b1\u3001\u5bdd\u6c57\u3001\u539f\u56e0\u4e0d\u660e\u306e\u4f53\u91cd\u6e1b\u5c11\u3001\u80f8\u75db\u3001\u811a\u306e\u3080\u304f\u307f\u3001\u3075\u304f\u3089\u306f\u304e\u306e\u5727\u75db\u3001\u307e\u305f\u306f\u606f\u5207\u308c\u304c\u73fe\u308c\u305f\u5834\u5408\u306f\u76f4\u3061\u306b\u5831\u544a\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/strong> \u2014 \u3053\u308c\u3089\u306f\u91cd\u7be4\u306a\u611f\u67d3\u75c7\u3001MACE\uff08\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff09\u3001\u307e\u305f\u306f\u8840\u6813\u75c7\u306e\u5146\u5019\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u751f\u30ef\u30af\u30c1\u30f3\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/strong> \u4e0d\u6d3b\u5316\u30ef\u30af\u30c1\u30f3\u306f\u554f\u984c\u306a\u304f\u3001\u63a8\u5968\u3055\u308c\u307e\u3059\uff08\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3001\u80ba\u708e\u7403\u83cc\u3001Shingrix\uff09\u3002<\/li>\n<li><strong>\u6bce\u65e5\u306eSPF 50\u306e\u65e5\u713c\u3051\u6b62\u3081<\/strong> \u2014 JAK\u963b\u5bb3\u5264\u306f\u975e\u9ed2\u8272\u816b\u76ae\u819a\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u307e\u3059\u3002\u76ae\u819a\u304c\u8272\u767d\u306e\u65b9\u3001\u76ae\u819a\u304c\u3093\u306e\u65e2\u5f80\u304c\u3042\u308b\u65b9\u3001\u307e\u305f\u306f12\u30f6\u6708\u4ee5\u4e0a\u306e\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u65b9\u306f\u3001\u6bce\u5e74\u306e\u76ae\u819a\u79d1\u691c\u8a3a\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002<\/li>\n<\/ol>\n<h2 class=\"wp-block-heading\">Barinat\u306e\u526f\u4f5c\u7528<\/h2>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:12px 0;border-radius:4px;font-size:14px;\"><strong>\u26a0\ufe0f FDA\u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a\u3002<\/strong> ORAL Surveillance\u8a66\u9a13\uff082021\u5e74\uff09\u306b\u57fa\u3065\u304d\u300150\u6b73\u4ee5\u4e0a\u3067\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u5c11\u306a\u304f\u3068\u30821\u3064\u6709\u3059\u308b\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6\u3068TNF\u963b\u5bb3\u5264\u3092\u6bd4\u8f03\u3057\u305f\u3082\u306e \u2014 \u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306b\u5916\u633f\uff1a<\/p>\n<ul style=\"margin:8px 0 0 0;\">\n<li><strong>\u91cd\u7be4\u306a\u611f\u67d3\u75c7<\/strong> \u2014 \u7d30\u83cc\u6027\u3001\u771f\u83cc\u6027\u3001\u30a6\u30a4\u30eb\u30b9\u6027\u3001\u6297\u9178\u83cc\u6027\uff08\u7d50\u6838\u518d\u6d3b\u6027\u5316\u3092\u542b\u3080\uff09\u3001\u65e5\u548c\u898b\u611f\u67d3\u75c7<\/li>\n<li><strong>\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09<\/strong> \u2014 \u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u8840\u7ba1\u6b7b\uff08\u9ad8\u30ea\u30b9\u30af\u96c6\u56e3\u3067\u306fTNF\u963b\u5bb3\u85ac\u3088\u308a\u9ad8\u7387\uff09<\/li>\n<li><strong>\u8840\u6813\u75c7<\/strong> \u2014 \u6df1\u90e8\u9759\u8108\u8840\u6813\u75c7\u3001\u80ba\u585e\u6813\u75c7\u3001\u52d5\u8108\u8840\u6813\u75c7<\/li>\n<li><strong>\u60aa\u6027\u816b\u760d<\/strong> \u2014 \u30ea\u30f3\u30d1\u816b\u3001\u80ba\u304c\u3093\uff08\u7279\u306b\u73fe\u55ab\u7159\u8005\uff0f\u5143\u55ab\u7159\u8005\u306b\u304a\u3044\u3066\uff09\u3001\u975e\u9ed2\u8272\u816b\u76ae\u819a\u304c\u3093<\/li>\n<li><strong>\u6b7b\u4ea1<\/strong> \u2014 \u9ad8\u30ea\u30b9\u30af\u30b3\u30db\u30fc\u30c8\u306b\u304a\u3044\u3066\u3001\u5168\u6b7b\u56e0\u6b7b\u4ea1\u7387\u306f\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6\u7fa4\u3067TNF\u963b\u5bb3\u85ac\u7fa4\u3088\u308a\u6570\u5024\u7684\u306b\u9ad8\u304b\u3063\u305f\u3002<\/li>\n<\/ul>\n<p style=\"margin:8px 0 0 0;\">\u73fe\u5728\u306eFDA\u30e9\u30d9\u30eb\u306b\u5f93\u3044\u3001JAK\u963b\u5bb3\u85ac\u306f\u30011\u3064\u4ee5\u4e0a\u306eTNF\u963b\u5bb3\u85ac\u306b\u5bfe\u3057\u3066\u52b9\u679c\u4e0d\u5341\u5206\u307e\u305f\u306f\u4e0d\u8010\u5bb9\u306e\u60a3\u8005\u306b\u9650\u308a\u4f7f\u7528\u3057\u3001\u4ee3\u66ff\u85ac\u304c\u4e0d\u9069\u5207\u306a\u5834\u5408\u3092\u9664\u304d\u307e\u3059\u3002<\/p>\n<\/div>\n<p><strong>\u4e00\u822c\u7684\u306a\u526f\u4f5c\u7528\uff1a<\/strong><\/p>\n<ul>\n<li>\u4e0a\u6c17\u9053\u611f\u67d3\u75c7\u3001\u9f3b\u54bd\u982d\u708e\u3001\u526f\u9f3b\u8154\u708e<\/li>\n<li>\u60aa\u5fc3\u3001\u4e0b\u75e2<\/li>\n<li>\u982d\u75db<\/li>\n<li>\u767a\u75b9\u3001\u3056\u7621\uff08\u7279\u306b4 mg\u6295\u4e0e\u6642\uff09<\/li>\n<li>\u5358\u7d14\u30d8\u30eb\u30da\u30b9\u304a\u3088\u3073 <strong>\u5e2f\u72b6\u75b1\u75b9\uff08\u5e2f\u72b6\u75b1\u75b9\uff09\u518d\u6d3b\u6027\u5316<\/strong> \u2014 \u30d0\u30c3\u30af\u30b0\u30e9\u30a6\u30f3\u30c9\u3088\u308a\u3082\u6709\u610f\u306b\u9ad8\u3044\u767a\u751f\u7387\u3001\u7279\u306b\u30a2\u30b8\u30a2\u4eba\u96c6\u56e3\u306b\u304a\u3044\u3066<\/li>\n<li>LDL\u3001HDL\u3001\u7dcf\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u306e\u4e0a\u6607<\/li>\n<li>ALT\/AST\u304a\u3088\u3073\u30af\u30ec\u30a2\u30c1\u30f3\u30ad\u30ca\u30fc\u30bc\u306e\u4e0a\u6607<\/li>\n<li>\u30ea\u30f3\u30d1\u7403\u6e1b\u5c11\u75c7\u3001\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7\u3001\u8ca7\u8840<\/li>\n<\/ul>\n<p><strong>\u983b\u5ea6\u306f\u4f4e\u3044\u304c\u91cd\u8981\u306a\u3082\u306e\uff1a<\/strong><\/p>\n<ul>\n<li>\u80ba\u708e\uff08\u7d30\u83cc\u6027\u304a\u3088\u3073\u65e5\u548c\u898b\u611f\u67d3\u3001 <em>\u30cb\u30e5\u30fc\u30e2\u30b7\u30b9\u30c1\u30b9<\/em>)<\/li>\n<li>\u8702\u7aa9\u7e54\u708e\u3001\u5c3f\u8def\u611f\u67d3\u75c7\u3001\u61a9\u5ba4\u708e\uff08\u9ad8\u9f62\u8005\u306b\u304a\u3051\u308b\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6\u306e\u7a7f\u5b54\u30ea\u30b9\u30af\u304c\u9ad8\u3044\uff09<\/li>\n<li>B\u578b\u809d\u708e\u306e\u518d\u6d3b\u6027\u5316<\/li>\n<li>\u9593\u8cea\u6027\u80ba\u75be\u60a3<\/li>\n<li>\u6d88\u5316\u7ba1\u7a7f\u5b54\uff08\u7279\u306bNSAIDs\u307e\u305f\u306f\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f75\u7528\u6642\uff09<\/li>\n<\/ul>\n<p><strong>\u307e\u308c\u3067\u3059\u304c\u91cd\u7be4\u2014\u76f4\u3061\u306b\u533b\u5e2b\u306e\u8a3a\u5bdf\u3092\u53d7\u3051\u3066\u304f\u3060\u3055\u3044\uff1a<\/strong><\/p>\n<ul>\n<li>\u6d3b\u52d5\u6027\u7d50\u6838\u307e\u305f\u306f\u64ad\u7a2e\u6027\u771f\u83cc\u611f\u67d3\u75c7\uff08\u767a\u71b1\u3001\u5bdd\u6c57\u3001\u6e7f\u6027\u54b3\u55fd\u3001\u4f53\u91cd\u6e1b\u5c11\uff09<\/li>\n<li>\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\uff08\u80f8\u75db\u3001\u8155\u3084\u984e\u306e\u75db\u307f\u3001\u7a81\u7136\u306e\u7247\u5074\u306e\u8131\u529b\u3001\u9854\u9762\u306e\u9ebb\u75fa\uff09<\/li>\n<li>\u6df1\u90e8\u9759\u8108\u8840\u6813\u75c7\uff0f\u80ba\u585e\u6813\u75c7\uff08\u7247\u811a\u306e\u816b\u308c\u3068\u3075\u304f\u3089\u306f\u304e\u306e\u5727\u75db\u3001\u7a81\u7136\u306e\u606f\u5207\u308c\u3001\u80f8\u819c\u6027\u80f8\u75db\uff09<\/li>\n<li>\u64ad\u7a2e\u6027\u5e2f\u72b6\u75b1\u75b9\u3001\u8133\u708e<\/li>\n<li>\u65b0\u305f\u306a\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\u307e\u305f\u306f\u539f\u56e0\u4e0d\u660e\u306e\u4f53\u91cd\u6e1b\u5c11\uff08\u30ea\u30f3\u30d1\u816b\u306e\u53ef\u80fd\u6027\uff09<\/li>\n<li>\u91cd\u7be4\u306a\u76ae\u819a\u53cd\u5fdc\uff08SJS\u3001TEN\u3001DRESS\uff09<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u8b66\u544a\u304a\u3088\u3073\u4f7f\u7528\u4e0a\u306e\u6ce8\u610f<\/h2>\n<ul>\n<li><strong>65\u6b73\u4ee5\u4e0a\u304b\u3064\uff0f\u307e\u305f\u306f\u73fe\u5728\uff0f\u904e\u53bb\u306e\u55ab\u7159\u8005<\/strong> \u2014 \u4e3b\u8981\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08MACE\uff09\u3001\u60aa\u6027\u816b\u760d\u304a\u3088\u3073\u6b7b\u4ea1\u306e\u30ea\u30b9\u30af\u304c\u8457\u3057\u304f\u9ad8\u3044\u3002\u4ee3\u66ff\u85ac\uff08TNF\u963b\u5bb3\u5264\u3001IL-6\u963b\u5bb3\u5264\uff09\u304c\u9069\u3055\u306a\u3044\u5834\u5408\u306b\u306e\u307f\u4f7f\u7528\u3057\u3001\u6709\u52b9\u6700\u4f4e\u7528\u91cf\u3092\u512a\u5148\u3059\u308b\u3053\u3068\u3002<\/li>\n<li><strong>\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3001\u9759\u8108\u8840\u6813\u585e\u6813\u75c7\uff08VTE\uff09\u3001\u6d3b\u52d5\u6027\u60aa\u6027\u816b\u760d\u3001\u307e\u305f\u306f\u30ea\u30f3\u30d1\u5897\u6b96\u6027\u75be\u60a3\u306e\u65e2\u5f80\u6b74<\/strong> \u2014 \u76f8\u5bfe\u7684\u307e\u305f\u306f\u7d76\u5bfe\u7684\u7981\u5fcc\uff1b\u5c02\u9580\u533b\u306e\u5224\u65ad\u3002<\/li>\n<li><strong>\u6d3b\u52d5\u6027\u306e\u91cd\u7be4\u306a\u611f\u67d3\u75c7<\/strong> \u2014 \u6295\u4e0e\u3092\u958b\u59cb\u3057\u306a\u3044\u3053\u3068\u3002\u767a\u71b1\u6027\u75be\u60a3\u4e2d\u306f\u4f11\u85ac\u3059\u308b\u3053\u3068\u3002<\/li>\n<li><strong>\u5e2f\u72b6\u75b1\u75b9\u518d\u6d3b\u6027\u5316<\/strong> \u2014 \u7279\u306b\u591a\u3044\u300250\u6b73\u4ee5\u4e0a\u307e\u305f\u306f\u305d\u306e\u4ed6\u306e\u63a5\u7a2e\u5bfe\u8c61\u8005\u3067\u3042\u308c\u3070\u3001\u958b\u59cb\u306e\u5c11\u306a\u304f\u3068\u30824\u9031\u9593\u524d\u306b\u7d44\u63db\u3048\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\uff08\u30b7\u30f3\u30b0\u30ea\u30c3\u30af\u30b9\uff09\u3092\u63a5\u7a2e\u3059\u308b\u3053\u3068\u3002<\/li>\n<li><strong>\u6162\u6027\uff0f\u518d\u767a\u6027\u611f\u67d3\u75c7\u3001\u7559\u7f6e\u30ab\u30c6\u30fc\u30c6\u30eb\u3001\u6700\u8fd1\u306e\u982d\u84cb\u5185\uff0f\u8179\u8154\u5185\u624b\u8853<\/strong> \u2014 \u500b\u5225\u306e\u30ea\u30b9\u30af\u30fb\u30d9\u30cd\u30d5\u30a3\u30c3\u30c8\u8a55\u4fa1\uff1b\u5c02\u9580\u533b\u306e\u30ec\u30d3\u30e5\u30fc\u3002<\/li>\n<li><strong>\u30ea\u30f3\u30d1\u7403\u6e1b\u5c11\u75c7\u3001\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7\u3001\u8ca7\u8840<\/strong> \u2014 ALC &lt; 0.5\u3001ANC &lt; 1.0\u3001\u307e\u305f\u306f Hb &lt; 8 g\/dL \u306e\u5834\u5408\u306f\u4e2d\u65ad\u3057\u3001\u56de\u5fa9\u5f8c\u306b\u4f4e\u7528\u91cf\u3067\u518d\u958b\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u8102\u8cea\u4e0a\u6607<\/strong> \u2014 \u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u306b\u57fa\u3065\u3044\u3066\u6cbb\u7642\u3057\u307e\u3059\u3002\u30b9\u30bf\u30c1\u30f3\u7cfb\u85ac\u5264\u306f\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u3068\u81e8\u5e8a\u7684\u306b\u91cd\u8981\u306a\u76f8\u4e92\u4f5c\u7528\u3092\u793a\u3057\u307e\u305b\u3093\u3002<\/li>\n<li><strong>\u61a9\u5ba4\u75be\u60a3<\/strong> \u2014 \u8178\u7ba1\u7a7f\u5b54\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u3001\u7279\u306b\u9ad8\u9f62\u8005\u3067\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6\u3068NSAIDs\u307e\u305f\u306f\u526f\u814e\u76ae\u8cea\u30b9\u30c6\u30ed\u30a4\u30c9\u3092\u4f75\u7528\u3057\u3066\u3044\u308b\u5834\u5408\u306b\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u598a\u5a20\u4e2d\u304a\u3088\u3073\u6388\u4e73\u4e2d<\/strong> \u2014 \u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002\u6cbb\u7642\u4e2d\u304a\u3088\u3073\u6700\u7d42\u6295\u4e0e\u5f8c\u5c11\u306a\u304f\u3068\u30821\u9031\u9593\u306f\u52b9\u679c\u7684\u306a\u907f\u598a\u304c\u5fc5\u8981\u3067\u3059\u3002\u6388\u4e73\u4e2d\u306e\u4f7f\u7528\u306f\u63a8\u5968\u3055\u308c\u307e\u305b\u3093\u3002<\/li>\n<li><strong>\u5c0f\u5150\u3078\u306e\u4f7f\u7528<\/strong> \u2014 \u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306f2\u6b73\u672a\u6e80\u306b\u306f\u9069\u5fdc\u304c\u306a\u304f\u30012\u6b73\u4ee5\u4e0a\u3067\u3082\u5c02\u9580\u533b\u306e\u5224\u65ad\u306b\u9650\u308a\u307e\u3059\u3002<\/li>\n<li><strong>\u751f\u30ef\u30af\u30c1\u30f3<\/strong> \u2014 \u6cbb\u7642\u4e2d\u306f\u7981\u5fcc\u3067\u3059\u3002\u751f\u30ef\u30af\u30c1\u30f3\uff08\u9ec4\u71b1\u3001MMR\u8ffd\u52a0\u63a5\u7a2e\u3001\u6c34\u75d8\u3001\u5e2f\u72b6\u75b1\u75b9\u751f\u30ef\u30af\u30c1\u30f3Zostavax\uff08\u30be\u30b9\u30bf\u30d0\u30c3\u30af\u30b9\uff09\u3001\u7d4c\u9f3b\u751f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\uff09\u304c\u5fc5\u8981\u306a\u5834\u5408\u306f\u3001\u6295\u4e0e\u958b\u59cb4\u9031\u9593\u524d\u307e\u3067\u306b\u63a5\u7a2e\u3057\u3001\u6295\u4e0e\u4e2d\u6b62\u5f8c1\uff5e2\u9031\u9593\u5f85\u3063\u3066\u304b\u3089\u518d\u63a5\u7a2e\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u7981\u5fcc \u2014 Barinat\uff08\u30d0\u30ea\u30ca\u30c3\u30c8\uff09\u3092\u670d\u7528\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u65b9<\/h2>\n<ul>\n<li>\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u307e\u305f\u306f\u6dfb\u52a0\u7269\u306b\u5bfe\u3059\u308b\u904e\u654f\u75c7\u306e\u65e2\u5f80<\/li>\n<li>\u6d3b\u52d5\u6027\u306e\u91cd\u7be4\u306a\u611f\u67d3\u75c7\uff08\u7d30\u83cc\u3001\u30a6\u30a4\u30eb\u30b9\u3001\u771f\u83cc\u3001\u6297\u9178\u83cc \u2014 \u6d3b\u52d5\u6027\u7d50\u6838\u3092\u542b\u3080\uff09<\/li>\n<li>\u672a\u6cbb\u7642\u306e\u6162\u6027B\u578b\u809d\u708e<\/li>\n<li>\u91cd\u5ea6\u809d\u969c\u5bb3\uff08Child-Pugh\u5206\u985eC\uff09<\/li>\n<li>\u91cd\u5ea6\u306e\u814e\u6a5f\u80fd\u969c\u5bb3\uff08eGFR &lt; 15 mL\/\u5206\uff09<\/li>\n<li>\u91cd\u5ea6\u306e\u30ea\u30f3\u30d1\u7403\u6e1b\u5c11\u75c7\uff08ALC &lt; 0.5\uff09\u3001\u597d\u4e2d\u7403\u6e1b\u5c11\u75c7\uff08ANC &lt; 1.0\uff09\u3001\u307e\u305f\u306f\u8ca7\u8840\uff08Hb &lt; 8 g\/dL\uff09<\/li>\n<li>\u598a\u5a20<\/li>\n<li>\u6700\u8fd16\u304b\u6708\u4ee5\u5185\u306e\u91cd\u5927\u306a\u5fc3\u8840\u7ba1\u6709\u5bb3\u4e8b\u8c61\uff08MACE\uff1a\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\uff09<\/li>\n<li>\u6d3b\u52d5\u6027\u60aa\u6027\u816b\u760d\uff08\u6cbb\u7642\u6e08\u307f\u306e\u975e\u30e1\u30e9\u30ce\u30fc\u30de\u76ae\u819a\u304c\u3093\u3092\u9664\u304f\uff09<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">\u85ac\u7269\u76f8\u4e92\u4f5c\u7528<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u4f75\u7528<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u52b9\u679c<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">\u5bfe\u51e6\u6cd5<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u5f37\u529b\u306aOAT3\u963b\u5bb3\u85ac\uff08\u30d7\u30ed\u30d9\u30cd\u30b7\u30c9\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306e\u8840\u4e2d\u6fc3\u5ea6\u3092\u7d042\u500d\u306b\u4e0a\u6607\u3055\u305b\u308b<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u7528\u91cf\u30921\u65e51\u56de2mg\u306b\u6e1b\u91cf\u3059\u308b.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u4ed6\u306e\u751f\u7269\u5b66\u7684DMARDs\uff08\u30a2\u30c0\u30ea\u30e0\u30de\u30d6\u3001\u30a8\u30bf\u30cd\u30eb\u30bb\u30d7\u30c8\u3001\u30a4\u30f3\u30d5\u30ea\u30ad\u30b7\u30de\u30d6\u3001\u30c8\u30b7\u30ea\u30ba\u30de\u30d6\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3001\u30a2\u30d0\u30bf\u30bb\u30d7\u30c8\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u76f8\u52a0\u7684\u306a\u514d\u75ab\u6291\u5236 \u2014 \u91cd\u5ea6\u306e\u611f\u67d3\u75c7\u30ea\u30b9\u30af<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>\u4f75\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/strong> \u5207\u308a\u66ff\u3048\u524d\u306b\u9069\u5207\u306a\u30a6\u30a9\u30c3\u30b7\u30e5\u30a2\u30a6\u30c8\u671f\u9593\u3092\u8a2d\u3051\u308b.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u4ed6\u306eJAK\u963b\u5bb3\u85ac\uff08\u30a6\u30d1\u30c0\u30b7\u30c1\u30cb\u30d6\u3001\u30d5\u30a3\u30eb\u30b4\u30c1\u30cb\u30d6\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u76f8\u52a0\u7684\u306a\u6bd2\u6027\u304c\u3042\u308a\u3001\u8ffd\u52a0\u306e\u6709\u76ca\u6027\u306f\u8a8d\u3081\u3089\u308c\u306a\u3044<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u4e00\u5ea6\u306b1\u7a2e\u985e\u306eJAK\u963b\u5bb3\u85ac\u306e\u307f\u4f7f\u7528\u3059\u308b.<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u79fb\u690d\u4ee5\u5916\u3067\u306e\u5f37\u529b\u306a\u514d\u75ab\u6291\u5236\u5264\uff08\u30a2\u30b6\u30c1\u30aa\u30d7\u30ea\u30f3\u3001\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u3001\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\u3001\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u611f\u67d3\u75c7\u304a\u3088\u3073\u30ea\u30f3\u30d1\u816b\u306e\u30ea\u30b9\u30af\u304c\u76f8\u52a0\u7684\u306b\u5897\u52a0<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u79fb\u690d\u4ee5\u5916\u306e\u72b6\u6cc1\u3067\u306f\u4f7f\u7528\u3092\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002\u79fb\u690d\u60a3\u8005\uff1a\u5c02\u9580\u533b\u306e\u5224\u65ad\u304c\u5fc5\u8981\u3067\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u751f\u30ef\u30af\u30c1\u30f3\uff08MMR\u3001\u6c34\u75d8\u3001\u5e2f\u72b6\u75b1\u75b9\u751f\u30ef\u30af\u30c1\u30f3\u3001\u7d4c\u9f3b\u751f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\u3001\u9ec4\u71b1\u3001BCG\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u30ef\u30af\u30c1\u30f3\u682a\u64ad\u7a2e\u6027\u611f\u67d3\u306e\u30ea\u30b9\u30af<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>\u6cbb\u7642\u4e2d\u306f\u7981\u5fcc\u3067\u3059\u3002<\/strong> \u958b\u59cb\u306e4\u9031\u9593\u4ee5\u4e0a\u524d\u306b\u63a5\u7a2e\u3059\u308b\u304b\u3001\u4e2d\u6b62\u5f8c1\uff5e2\u9031\u9593\u5f85\u3061\u307e\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">NSAIDs\u3068\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u4f75\u7528<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u6d88\u5316\u7ba1\u7a7f\u5b54\u30ea\u30b9\u30af\u306e\u5897\u52a0\uff08\u7279\u306b\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6\uff0b\u9ad8\u9f62\u8005\uff0b\u61a9\u5ba4\u75be\u60a3\u3067\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u4e21\u5264\u3092\u6700\u5c0f\u6709\u52b9\u91cf\u3067\u4f7f\u7528\u3057\u3001\u9577\u671f\u4f75\u7528\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\uff08\u4f4e\u7528\u91cf\u3001\u90311\u56de\uff09<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306b\u304a\u3051\u308b\u6a19\u6e96\u7684\u306a\u4f75\u7528 \u2014 \u85ac\u7269\u52d5\u614b\u5b66\u7684\u76f8\u4e92\u4f5c\u7528\u306f\u3042\u308a\u307e\u305b\u3093<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">\u80cc\u666fDMARD\u3068\u3057\u3066\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u3092\u7d99\u7d9a\u3057\u3001CBC\u3068LFT\u3092\u5408\u308f\u305b\u3066\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 class=\"wp-block-heading\">\u4fdd\u7ba1\u65b9\u6cd5<\/h2>\n<ul>\n<li>\u5ba4\u6e29\u3067\u4fdd\u5b58\u3057\u3001, <strong>30\u00b0C\u4ee5\u4e0b<\/strong>, \u3001\u5143\u306e\u30d6\u30ea\u30b9\u30bf\u30fc\u5305\u88c5\u306e\u307e\u307e\u3002<\/li>\n<li>\u5149\u3068\u6e7f\u6c17\u304b\u3089\u4fdd\u8b77\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u6d74\u5ba4\u3067\u306e\u4fdd\u7ba1\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u304a\u5b50\u69d8\u306e\u624b\u306e\u5c4a\u304b\u306a\u3044\u5834\u6240\u306b\u4fdd\u7ba1\u3057\u3066\u304f\u3060\u3055\u3044 \u2014 \u8aa4\u3063\u3066\u670d\u7528\u3059\u308b\u3068\u91cd\u5ea6\u306e\u514d\u75ab\u6291\u5236\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<li>\u30d1\u30c3\u30b1\u30fc\u30b8\u306b\u8a18\u8f09\u3055\u308c\u305f\u4f7f\u7528\u671f\u9650\u3092\u904e\u304e\u305f\u3082\u306e\u306f\u4f7f\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u672a\u4f7f\u7528\u306e\u9320\u5264\u306f\u85ac\u5c40\u306b\u8fd4\u5374\u3057\u3066\u5ec3\u68c4\u3057\u3066\u304f\u3060\u3055\u3044 \u2014 \u30c8\u30a4\u30ec\u306b\u6d41\u3057\u305f\u308a\u5bb6\u5ead\u3054\u307f\u3068\u3057\u3066\u6368\u3066\u305f\u308a\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">MedsBase\u3067\u3054\u89a7\u3044\u305f\u3060\u3051\u308b\u95a2\u9023\u4ee3\u66ff\u54c1<\/h2>\n<p>\u3053\u306e\u88fd\u54c1\u3068\u4e00\u7dd2\u306b\u53d6\u308a\u6271\u3063\u3066\u3044\u308b\u3001\u6297\u708e\u75c7\u304a\u3088\u3073\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u6cbb\u7642\u306b\u4f7f\u7528\u3055\u308c\u308b\u305d\u306e\u4ed6\u306e\u533b\u85ac\u54c1\uff1a<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ja\/tofe\/\"><strong>Tofe\uff08\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6 5 mg\uff09\u2014 RA\u3001UC\u3001PsA\u306b\u5bfe\u3059\u308bJAK1\/3\u963b\u5bb3\u5264<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/azoran\/\"><strong>Azoran\uff08\u30a2\u30b6\u30c1\u30aa\u30d7\u30ea\u30f3 50 mg\uff09\u2014 \u53e4\u5178\u7684\u306a\u514d\u75ab\u6291\u5236\u6027DMARD<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/lefuheal\/\"><strong>Lefuheal\uff08\u30ec\u30d5\u30eb\u30ce\u30df\u30c9\uff09\u2014 \u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306b\u5bfe\u3059\u308b\u7d4c\u53e3DMARD<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/conimune-me\/\"><strong>Conimune ME\uff08\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\uff09\u2014 \u30ab\u30eb\u30b7\u30cb\u30e5\u30fc\u30ea\u30f3\u963b\u5bb3\u5264<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/wysolone\/\"><strong>Wysolone\uff08\u30d7\u30ec\u30c9\u30cb\u30be\u30ed\u30f3 5 \/ 10 \/ 20 mg\uff09\u2014 \u7d4c\u53e3\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/medrol\/\"><strong>Medrol\uff08\u30e1\u30c1\u30eb\u30d7\u30ec\u30c9\u30cb\u30be\u30ed\u30f3 4 \/ 8 \/ 16 mg\uff09\u2014 \u7d4c\u53e3\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/predniheal\/\"><strong>Predniheal\uff08\u30d7\u30ec\u30c9\u30cb\u30be\u30ed\u30f3\uff09\u2014 \u7d4c\u53e3\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/hisone\/\"><strong>Hisone\uff08\u30d2\u30c9\u30ed\u30b3\u30eb\u30c1\u30be\u30f3\uff09\u2014 \u751f\u7406\u7684\u88dc\u5145\u30b9\u30c6\u30ed\u30a4\u30c9<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/budez-cr\/\"><strong>Budez CR\uff08\u30d6\u30c7\u30bd\u30cb\u30c9\uff09\u2014 \u30af\u30ed\u30fc\u30f3\u75c5\u306b\u5bfe\u3059\u308b\u8178\u7ba1\u6a19\u7684\u578b\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/kenacort\/\"><strong>Kenacort\uff08\u30c8\u30ea\u30a2\u30e0\u30b7\u30ce\u30ed\u30f3\uff09\u2014 \u5168\u8eab\u6027\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9<\/strong><\/a><\/li>\n<\/ul>\n<p>\u3059\u3079\u3066\u3092\u898b\u308b <a href=\"https:\/\/medsbase.com\/ja\/anti-inflammatory-autoimmune-care\/\">DMARDs\u3001\u751f\u7269\u5b66\u7684\u88fd\u5264\u306e\u88dc\u52a9\u85ac\u3001\u514d\u75ab\u8abf\u7bc0\u85ac\u306a\u3069\u3092\u53d6\u308a\u6271\u3063\u3066\u3044\u307e\u3059\u3002<\/a> \u30ab\u30c6\u30b4\u30ea\u30fc\u3002<\/p>\n<h2 id=\"faqs\">\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n<h3 class=\"wp-block-heading\">Barinat\uff08\u30d0\u30ea\u30ca\u30c3\u30c8\uff09\u306e\u52b9\u679c\u3092\u611f\u3058\u59cb\u3081\u308b\u306e\u306f\u3044\u3064\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u95a2\u7bc0\u75db\u3068\u671d\u306e\u3053\u308f\u3070\u308a\u306f\u3001\u901a\u5e38\u3001\u6539\u5584\u3059\u308b\u307e\u3067\u306b <strong>2\uff5e4\u9031\u9593<\/strong>. \u81e8\u5e8a\u53cd\u5fdc\u306e\u30d4\u30fc\u30af\u306f3\uff5e6\u304b\u6708\u3067\u73fe\u308c\u307e\u3059\u3002\u9069\u5207\u306a\u7528\u91cf\u306712\uff5e16\u9031\u9593\u3092\u7d4c\u904e\u3057\u3066\u3082\u6709\u610f\u306a\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u306a\u3044\u5834\u5408\u3001\u307b\u3068\u3093\u3069\u306e\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\u306f\u3001\u6f2b\u7136\u3068\u7d99\u7d9a\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u4ed6\u306e\u6a19\u7684\u7642\u6cd5\u3078\u306e\u5207\u308a\u66ff\u3048\u3092\u691c\u8a0e\u3057\u307e\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">Barinat\uff08\u30d0\u30ea\u30ca\u30c3\u30c8\uff09\u306e\u6295\u4e0e\u958b\u59cb\u524d\u306b\u3001\u7d50\u6838\uff08TB\uff09\u304a\u3088\u3073B\u578b\u809d\u708e\u306e\u691c\u67fb\u304c\u5fc5\u8981\u306a\u306e\u306f\u306a\u305c\u3067\u3059\u304b\uff1f<\/h3>\n<p>JAK\u963b\u5bb3\u85ac\u306f\u6f5c\u4f0f\u611f\u67d3\u3092\u518d\u6d3b\u6027\u5316\u3055\u305b\u307e\u3059\u3002\u6f5c\u5728\u6027\u7d50\u6838\u306f\u60a3\u8005\u306e\u7d041\uff05\u3067\u518d\u71c3\u3057\u3001\u6162\u6027B\u578b\u809d\u708e\u306f\u7206\u767a\u7684\u306b\u518d\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u3092\u9632\u3050\u552f\u4e00\u306e\u65b9\u6cd5\u306f\u3001\u521d\u56de\u6295\u4e0e\u524d\u306e\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3068\u3001\u967d\u6027\u3068\u306a\u3063\u305f\u65b9\u306e\u6cbb\u7642\uff08\u307e\u305f\u306f\u6297\u30a6\u30a4\u30eb\u30b9\u85ac\u306b\u3088\u308b\u4e88\u9632\u7684\u5bfe\u5fdc\uff09\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u691c\u67fb\u3092\u7701\u7565\u3059\u308b\u3053\u3068\u306f\u3001JAK\u7642\u6cd5\u306b\u304a\u3044\u3066\u56de\u907f\u53ef\u80fd\u306a\u91cd\u7be4\u306a\u5bb3\u306e\u3001\u6700\u3082\u4e00\u822c\u7684\u306a\u539f\u56e0\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">Barinat\uff08\u30d0\u30ea\u30ca\u30c3\u30c8\uff09\u306b\u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a\u304c\u3042\u308b\u306e\u306f\u306a\u305c\u3067\u3059\u304b\uff1f<\/h3>\n<p>FDA\u306f2021\u5e749\u6708\u306b\u3001\u30af\u30e9\u30b9\u5168\u4f53\u3092\u5bfe\u8c61\u3068\u3059\u308b\u30d6\u30e9\u30c3\u30af\u30dc\u30c3\u30af\u30b9\u8b66\u544a\u3092\u8ffd\u52a0\u3057\u307e\u3057\u305f\u304c\u3001\u305d\u308c\u306f <strong>ORAL Surveillance\uff08\u30aa\u30fc\u30e9\u30eb\u30fb\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\uff09<\/strong> \u8a66\u9a13\u3067\u306f\u3001\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u306b\u627f\u8a8d\u3055\u308c\u305f\u7528\u91cf\u306e\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6\u304c\u3001TNF\u963b\u5bb3\u5264\u3068\u6bd4\u8f03\u3057\u3066\u3001\u4e3b\u8981\u6709\u5bb3\u5fc3\u8840\u7ba1\u30a4\u30d9\u30f3\u30c8\uff08\u5fc3\u7b4b\u6897\u585e\u3001\u8133\u5352\u4e2d\u3001\u5fc3\u8840\u7ba1\u6b7b\uff09\u3001\u60aa\u6027\u816b\u760d\uff08\u7279\u306b\u55ab\u7159\u8005\u306b\u304a\u3051\u308b\u80ba\u304c\u3093\uff09\u3001\u8840\u6813\u3001\u5168\u6b7b\u4ea1\u304c\u3088\u308a\u591a\u304f\u767a\u751f\u3057\u305f\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f \u2014 \u7279\u306b50\u6b73\u4ee5\u4e0a\u3067\u5c11\u306a\u304f\u3068\u30821\u3064\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u6709\u3059\u308bRA\u60a3\u8005\u306b\u304a\u3044\u3066\u3002\u3053\u306e\u8b66\u544a\u306fJAK\u963b\u5bb3\u85ac\u30af\u30e9\u30b9\u5168\u4f53\u306b\u62e1\u5927\u3055\u308c\u307e\u3057\u305f\u3002\u73fe\u884c\u306eFDA\u30ac\u30a4\u30c0\u30f3\u30b9\u3067\u306f\u3001JAK\u963b\u5bb3\u85ac\u306f\u3001TNF\u963b\u5bb3\u5264\u304c\u7121\u52b9\u307e\u305f\u306f\u4f7f\u7528\u3067\u304d\u306a\u3044\u60a3\u8005\u306b\u9650\u308a\u6700\u521d\u306b\u4f7f\u7528\u3059\u308b\u3053\u3068\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u30d0\u30ea\u30ca\u30c3\u30c8\u306f\u9577\u671f\u4f7f\u7528\u3057\u3066\u3082\u5b89\u5168\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u9577\u671f\u30c7\u30fc\u30bf\uff08\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d6\u6700\u95779.5\u5e74\uff09\u3067\u306f\u3001\u6a19\u6e96\u30ea\u30b9\u30af\u60a3\u8005\u306b\u304a\u3051\u308b\u5fc3\u8840\u7ba1\u304a\u3088\u3073\u60aa\u6027\u816b\u760d\u306e\u767a\u751f\u7387\u306f\u3001\u4e00\u822c\u96c6\u56e3\u3068\u540c\u7a0b\u5ea6\u306b\u7559\u307e\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002ORAL Surveillance\u8a66\u9a13\u304b\u3089\u306e\u30b7\u30b0\u30ca\u30eb\u306f\u3001\u65e2\u5b58\u306e\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\u3092\u6709\u3059\u308b\u9ad8\u9f62\u60a3\u8005\u306b\u96c6\u4e2d\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u4ed6\u306e\u5065\u5eb7\u306a\u82e5\u5e74\u306eRA\u60a3\u8005\u3067\u306f\u3001\u9577\u671f\u306e\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306f\u59a5\u5f53\u306a\u9078\u629e\u80a2\u3067\u3059\u304c\u3001\u5e74\u306b1\u56de\u306e\u76ae\u819a\u691c\u67fb\u3001\u8102\u8cea\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3001\u8840\u7b97\u3001\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u72b6\u6cc1\u306e\u78ba\u8a8d\u306f\u5f15\u304d\u7d9a\u304d\u5fc5\u9808\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u30d0\u30ea\u30ca\u30c3\u30c8\u3067\u5e2f\u72b6\u75b1\u75b9\u306b\u306a\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u6f5c\u4f0f\u6027\u6c34\u75d8\u30fb\u5e2f\u72b6\u75b1\u75b9\u30a6\u30a4\u30eb\u30b9\u306e\u518d\u6d3b\u6027\u5316\uff08\u5e2f\u72b6\u75b1\u75b9\uff09\u306f\u3001JAK\u963b\u5bb3\u85ac\u3067\u306fTNF\u963b\u5bb3\u85ac\u3084\u4e00\u822c\u96c6\u56e3\u3088\u308a\u3082\u6709\u610f\u306b\u9ad8\u983b\u5ea6\u3067\u767a\u751f\u3057\u307e\u3059 \u2014 \u767a\u751f\u7387\u306f2\uff5e5\u500d\u9ad8\u304f\u3001\u30a2\u30b8\u30a2\u4eba\u60a3\u8005\u3067\u6700\u3082\u30ea\u30b9\u30af\u304c\u9ad8\u304f\u306a\u308a\u307e\u3059\u300250\u6b73\u4ee5\u4e0a\u307e\u305f\u306f\u514d\u75ab\u4e0d\u5168\u306e\u65b9\u306f\u3001\u30d0\u30ea\u30ca\u30c3\u30c8\u958b\u59cb\u306e\u5c11\u306a\u304f\u3068\u30824\u9031\u9593\u524d\u306b\u3001\u7d44\u63db\u3048\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\uff08Shingrix\u30012\u56de\u63a5\u7a2e\uff09\u3092\u63a5\u7a2e\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u5f31\u6bd2\u751f\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\uff08Zostavax\uff09\u306fJAK\u963b\u5bb3\u7642\u6cd5\u4e2d\u306f\u7981\u5fcc\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u30d0\u30ea\u30ca\u30c3\u30c8\u306f\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u3068\u4f75\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u306f\u3044 \u2014 \u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u306f\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\u3067\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u3068\u4f75\u7528\u3055\u308c\u308b\u6a19\u6e96\u7684\u306a\u80cc\u666fDMARD\u3067\u3042\u308a\u3001\u4f75\u7528\u7642\u6cd5\u306f\u307b\u3068\u3093\u3069\u306e\u8a66\u9a13\u3067\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u5358\u72ec\u3088\u308a\u3082\u826f\u597d\u306a\u7d50\u679c\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002\u85ac\u7269\u52d5\u614b\u5b66\u7684\u76f8\u4e92\u4f5c\u7528\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u4e21\u5264\u306e\u4f7f\u7528\u4e2d\u306f\u5b9a\u671f\u7684\u306b\u8840\u7b97\u3068\u809d\u6a5f\u80fd\u691c\u67fb\uff08LFT\uff09\u3092\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002JAK\u963b\u5bb3\u85ac\u306f <strong>\u3057\u307e\u305b\u3093<\/strong> \u751f\u7269\u5b66\u7684DMARD\uff08TNF\u963b\u5bb3\u85ac\u3001IL-6\u963b\u5bb3\u85ac\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3001\u30a2\u30d0\u30bf\u30bb\u30d7\u30c8\uff09\u3068\u4f75\u7528\u3059\u308b\u3053\u3068 \u2014 \u611f\u67d3\u30ea\u30b9\u30af\u304c\u5bb9\u8a8d\u3067\u304d\u307e\u305b\u3093\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u598a\u5a20\u4e2d\u304a\u3088\u3073\u6388\u4e73\u4e2d\u306e\u4f7f\u7528\u306b\u3064\u3044\u3066\u306f\u3069\u3046\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306f <strong>\u63a8\u5968\u3055\u308c\u307e\u305b\u3093<\/strong> \u598a\u5a20\u4e2d \u2014 \u52d5\u7269\u5b9f\u9a13\u3067\u306f\u9aa8\u683c\u304a\u3088\u3073\u5185\u81d3\u306e\u50ac\u5947\u5f62\u6027\u304c\u793a\u3055\u308c\u3066\u304a\u308a\u3001\u30d2\u30c8\u306e\u30c7\u30fc\u30bf\u306f\u4e0d\u5341\u5206\u3067\u3059\u3002\u6cbb\u7642\u4e2d\u304a\u3088\u3073\u6700\u7d42\u6295\u4e0e\u5f8c\u5c11\u306a\u304f\u3068\u30821\u9031\u9593\u306f\u3001\u52b9\u679c\u7684\u306a\u907f\u598a\u3092\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002\u6388\u4e73\u4e2d\u306f\u4f7f\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044 \u2014 \u30d0\u30ea\u30b7\u30c1\u30cb\u30d6\u306f\u6bcd\u4e73\u4e2d\u306b\u79fb\u884c\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3001\u4e73\u5150\u306b\u5f71\u97ff\u3092\u53ca\u307c\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u598a\u5a20\u3092\u8a08\u753b\u3059\u308b\u5834\u5408\u306f\u3001\u30ea\u30a6\u30de\u30c1\u5c02\u9580\u533b\u3068\u76f8\u8ac7\u3057\u3001\u598a\u5a20\u306b\u9069\u5408\u3057\u305fDMARD\uff08\u30d2\u30c9\u30ed\u30ad\u30b7\u30af\u30ed\u30ed\u30ad\u30f3\u3001\u30bb\u30eb\u30c8\u30ea\u30ba\u30de\u30d6\u3001\u30b9\u30eb\u30d5\u30a1\u30b5\u30e9\u30b8\u30f3\uff09\u306b\u598a\u5a20\u524d\u306b\u5207\u308a\u66ff\u3048\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u98a8\u90aa\u3084\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u304b\u304b\u3063\u305f\u5834\u5408\u3001\u30d0\u30ea\u30ca\u30c3\u30c8\u3092\u4e2d\u6b62\u3059\u3079\u304d\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u767a\u71b1\u306e\u306a\u3044\u8efd\u5ea6\u306e\u4e0a\u6c17\u9053\u611f\u67d3\u306e\u5834\u5408\u306f\u3001\u85ac\u3092\u7d9a\u3051\u3066\u7d4c\u904e\u89b3\u5bdf\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u3088\u308a\u6df1\u523b\u306a\u5834\u5408 \u2014 38\u2103\u4ee5\u4e0a\u306e\u767a\u71b1\u3001\u6e7f\u6027\u54b3\u55fd\u3001\u814e\u76c2\u814e\u708e\u306e\u75c7\u72b6\u3001\u8702\u7aa9\u7e54\u708e\u3001\u5e2f\u72b6\u75b1\u75b9\u306e\u767a\u75c7\u3001\u80ba\u708e\u306e\u7591\u3044\u3001\u307e\u305f\u306f\u6cbb\u7642\u3092\u8981\u3059\u308bCOVID-19 \u2014 \u76f4\u3061\u306b\u30d0\u30ea\u30ca\u30c3\u30c8\u3092\u4e2d\u6b62\u3057\u3001\u51e6\u65b9\u533b\u306b\u9023\u7d61\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u611f\u67d3\u304c\u5b8c\u5168\u306b\u6cbb\u7652\u3057\u305f\u5f8c\u306b\u518d\u958b\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u3053\u306e\u300c\u611f\u67d3\u4e2d\u306f\u4e00\u6642\u4f11\u6b62\u300d\u3068\u3044\u3046\u30eb\u30fc\u30eb\u306f\u3001JAK\u963b\u5bb3\u7642\u6cd5\u306b\u304a\u3051\u308b\u6700\u3082\u91cd\u8981\u306a\u81ea\u5df1\u7ba1\u7406\u30b9\u30ad\u30eb\u3067\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">\u3069\u306e\u3088\u3046\u306a\u81e8\u5e8a\u691c\u67fb\u304c\u5fc5\u8981\u3067\u3001\u3069\u306e\u304f\u3089\u3044\u306e\u983b\u5ea6\u3067\u884c\u3046\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u30d0\u30ea\u30ca\u30c3\u30c8\u958b\u59cb\u5f8c\u306e\u6a19\u6e96\u7684\u306a\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\uff1a <strong>4\u9031\u76ee\u30018\u9031\u76ee\u300112\u9031\u76ee\u306b\u767d\u8840\u7403\u5206\u753b\u3092\u542b\u3080\u5168\u8840\u7403\u8a08\u7b97\u3068\u809d\u6a5f\u80fd\u691c\u67fb\u3092\u5b9f\u65bd\u3057\u3001\u305d\u306e\u5f8c\u306f3\u304b\u6708\u3054\u3068\u306b\u691c\u67fb\u3057\u307e\u3059\u3002<\/strong> <strong>8\u9031\u76ee\u306b\u8102\u8cea\u30d1\u30cd\u30eb\u3092\u5b9f\u65bd\u3057\u3001\u305d\u306e\u5f8c\u306f\u5e741\u56de\u691c\u67fb\u3057\u307e\u3059\u3002<\/strong> <strong>\u814e\u6a5f\u80fd\u306f3\uff5e6\u304b\u6708\u3054\u3068\u306b\u691c\u67fb\u3057\u307e\u3059\u3002<\/strong> \u8272\u767d\u306e\u60a3\u8005\u3001\u76ae\u819a\u304c\u3093\u306e\u65e2\u5f80\u304c\u3042\u308b\u60a3\u8005\u3001\u307e\u305f\u306f\u6cbb\u7642\u958b\u59cb\u304b\u308912\u304b\u6708\u3092\u7d4c\u904e\u3057\u305f\u60a3\u8005\u3067\u306f\u3001\u5e741\u56de\u306e\u76ae\u819a\u79d1\u53d7\u8a3a\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u3002\u30ea\u30f3\u30d1\u7403\u304c0.5\u00d710\u2079\/L\u672a\u6e80\u3001\u597d\u4e2d\u7403\u304c1.0\u672a\u6e80\u3001\u307e\u305f\u306fALT\u304c\u6b63\u5e38\u4e0a\u9650\u306e3\u500d\u3092\u8d85\u3048\u305f\u5834\u5408\u306f\u3001\u3044\u305a\u308c\u3082\u56de\u5fa9\u3059\u308b\u307e\u3067\u6cbb\u7642\u3092\u4e2d\u65ad\u3057\u307e\u3059\u3002<\/p>\n<h3 class=\"wp-block-heading\">MedsBase\u3067\u6ce8\u6587\u3059\u308b\u7406\u7531<\/h3>\n<p>Barinat\u306f\u3001\u5b8c\u5168\u306aCOA\u6587\u66f8\u3092\u5099\u3048\u305fWHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u4f9b\u7d66\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u68b1\u5305\u3067\u5168\u4e16\u754c\u914d\u9001\u3092\u884c\u3044\u3001\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u5f53\u5e97\u306e <a href=\"\/ja\/medsbase-re-shipment-assurance-policy\/\">\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/a>. \u30ab\u30fc\u30c9\u3067\u306e\u304a\u652f\u6255\u3044\u6642\u306e\u660e\u7d30\u306b\u306f\u3001\u898f\u5236\u4e0b\u306e\u30ab\u30fc\u30c9\u6c7a\u6e08\u51e6\u7406\u696d\u8005\u304c\u8868\u793a\u3055\u308c\u307e\u3059\u3002\u300cMedsBase\u300d\u3084\u533b\u85ac\u54c1\u540d\u304c\u8868\u793a\u3055\u308c\u308b\u3053\u3068\u306f\u4e00\u5207\u3054\u3056\u3044\u307e\u305b\u3093\u3002<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">\u305d\u306e\u4ed6\u306e\u6297\u708e\u75c7\u85ac\u30fb\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u6cbb\u7642\u85ac<\/h3>\n<p>Barinat\u304c\u3054\u72b6\u6cc1\u306b\u5408\u308f\u306a\u3044\u5834\u5408\u3001\u3053\u306e\u30ab\u30c6\u30b4\u30ea\u30fc\u3067\u306f\u4ee5\u4e0b\u306e\u9078\u629e\u80a2\u3082\u3054\u5229\u7528\u3044\u305f\u3060\u3051\u307e\u3059\uff1a<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/ja\/tofe\/\">Tofe\uff08\u30c8\u30d5\u30a1\u30b7\u30c1\u30cb\u30d65 mg\u3001Intas\uff09\u2014 RA\u3001UC\u3001PsA\u306b\u9069\u5fdc\u306e\u3042\u308b\u6c4eJAK\u963b\u5bb3\u85ac<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/wysolone\/\">Wysolone\uff08\u30d7\u30ec\u30c9\u30cb\u30be\u30ed\u30f35\/10\/20 mg\u3001Wyeth\uff09\u2014 \u6025\u6027\u5897\u60aa\u6642\u306e\u6a4b\u6e21\u3057\u7684\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/kenacort\/\">Kenacort\uff08\u30c8\u30ea\u30a2\u30e0\u30b7\u30ce\u30ed\u30f34 mg\u3001Abbott\uff09\u2014 \u7d4c\u53e3\u30b3\u30eb\u30c1\u30b3\u30b9\u30c6\u30ed\u30a4\u30c9<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/azoran\/\">Azoran\uff08\u30a2\u30b6\u30c1\u30aa\u30d7\u30ea\u30f3 50 mg\u3001RPG\uff09\u2014 \u30d7\u30ea\u30f3\u4ee3\u8b1d\u62ee\u6297\u85ac\u3001\u5f93\u6765\u578bDMARD<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/ja\/lefuheal\/\">Lefuheal\uff08\u30ec\u30d5\u30eb\u30ce\u30df\u30c910\/20 mg\u3001Healing Pharma\uff09\u2014 \u30d4\u30ea\u30df\u30b8\u30f3\u5408\u6210\u963b\u5bb3\u85ac<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 \u95a2\u7bc0\u306e\u816b\u308c\u3092\u8efd\u6e1b<br \/>\n\u2705 \u30ea\u30a6\u30de\u30c1\u306e\u3053\u308f\u3070\u308a\u3092\u7de9\u548c<br \/>\n\u2705 \u514d\u75ab\u8abf\u7bc0\u3092\u6539\u5584<br \/>\n\u2705 \u95a2\u7bc0\u640d\u50b7\u306e\u9032\u884c\u3092\u9045\u5ef6<br \/>\n\u2705 \u6bce\u65e5\u306e\u53ef\u52d5\u6027\u3092\u5411\u4e0a<\/p>\n<p><strong>Barinat<\/strong> \u542b\u6709 <strong>\u30d0\u30ea\u30b7\u30c1\u30cb\u30d6<\/strong>.<\/p>","protected":false},"featured_media":66716,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3897,3141,3223],"product_tag":[5361,5360],"class_list":{"0":"post-66715","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-inflammatory-autoimmune-care","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-baricitinib","10":"product_tag-barinat","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product\/66715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/comments?post=66715"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/media\/66716"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/media?parent=66715"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_brand?post=66715"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_cat?post=66715"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/ja\/wp-json\/wp\/v2\/product_tag?post=66715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}