{"id":71388,"date":"2026-05-20T08:30:59","date_gmt":"2026-05-20T08:30:59","guid":{"rendered":"https:\/\/medsbase.com\/ara-290\/"},"modified":"2026-05-21T07:14:09","modified_gmt":"2026-05-21T07:14:09","slug":"ara-290","status":"publish","type":"product","link":"https:\/\/medsbase.com\/ja\/product\/ara-290\/","title":{"rendered":"ARA-290 (Cibinetide)"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background: #fff8e1; border-left: 4px solid #f5a623; padding: 18px 22px; margin: 18px 0; border-radius: 4px;\">\n<h3 style=\"margin: 0 0 8px 0; font-size: 16px; color: #1a4a6b;\">\u30af\u30a4\u30c3\u30af\u30a2\u30f3\u30b5\u30fc \u2014 ARA-290\u3068\u306f\uff1f<\/h3>\n<p style=\"margin: 0;\"><strong>ARA-290<\/strong> \uff08\u30b7\u30d3\u30cd\u30c1\u30c9; Helix B Surface Peptide, HBSP\uff09\u306f\u3001\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\uff08EPO\uff09\u306e\u30d8\u30ea\u30c3\u30af\u30b9B\u306b\u7531\u6765\u3059\u308b11\u30a2\u30df\u30ce\u9178\u306e\u5408\u6210\u30da\u30d7\u30c1\u30c9\u3067\u3059\u3002Brines &amp; Cerami\u306b\u3088\u3063\u3066\u8a2d\u8a08\u3055\u308c\u3001EPO\u306e\u7d30\u80de\u4fdd\u8b77\u4f5c\u7528\u3068\u9020\u8840\u4f5c\u7528\u3092\u5206\u96e2\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3001ARA-290\u306f\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08IRR\uff09\u2014EPO\u53d7\u5bb9\u4f53\u3068\u03b2\u5171\u901a\u53d7\u5bb9\u4f53\uff08CD131\uff09\u306e\u30d8\u30c6\u30ed\u8907\u5408\u4f53\u2014\u306b\u7d50\u5408\u3057\u3001\u8d64\u8840\u7403\u91cf\u3092\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u306a\u304f\u3001\u6297\u708e\u75c7\u3001\u6297\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3001\u7d44\u7e54\u4fee\u5fa9\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002Araim Pharmaceuticals\u306b\u3088\u308a\u958b\u767a\uff1b\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u95a2\u9023\u5c0f\u5f84\u7dda\u7dad\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u306b\u5bfe\u3059\u308b\u30aa\u30fc\u30d5\u30a1\u30f3\u6307\u5b9a\u300210 mg\u306e\u51cd\u7d50\u4e7e\u71e5\u30d0\u30a4\u30a2\u30eb\u3067\u4f9b\u7d66\u3055\u308c\u3001\u7814\u7a76\u5ba4\u7814\u7a76\u7528\u306e\u307f\u306b\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background: #f4f8fb; border: 1px solid #d8e3eb; padding: 12px 16px; margin: 16px 0; border-radius: 4px; font-size: 14px;\"><strong>MedsBase\u3067\u5f97\u3089\u308c\u308b\u3082\u306e\uff1a<\/strong> \u7814\u7a76\u30b0\u30ec\u30fc\u30c9\u306e\u51cd\u7d50\u4e7e\u71e5\u30da\u30d7\u30c1\u30c9 \u00b7 HPLC\u7d14\u5ea699%\u4ee5\u4e0a\uff08COA\u306f\u3054\u8981\u671b\u306b\u5fdc\u3058\u3066\uff09 \u00b7 \u4e2d\u8eab\u304c\u308f\u304b\u3089\u306a\u3044\u6e29\u5ea6\u5b89\u5b9a\u6027\u5305\u88c5 \u00b7 \u30da\u30d7\u30c1\u30c9\u306e\u5168\u4e16\u754c\u914d\u9001 \u00b7 1,400\u4ef6\u4ee5\u4e0a\u306e\u691c\u8a3c\u6e08\u307f <a href=\"https:\/\/medsbase.com\/ja\/reviews\/\">\u30ab\u30b9\u30bf\u30de\u30fc\u30ec\u30d3\u30e5\u30fc<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size: 14px; color: #444; margin: 8px 0 18px;\">\ud83d\udce6 \u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306f\u3001\u5f53\u5e97\u306e <a href=\"https:\/\/medsbase.com\/ja\/medsbase-re-shipment-assurance-policy\/\"><strong>\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong><\/a> \u2014 \u4e07\u304c\u4e00\u300120\u55b6\u696d\u65e5\u4ee5\u5185\u306b\u5546\u54c1\u304c\u5c4a\u304b\u306a\u3044\u5834\u5408\u306f\u3001\u518d\u767a\u9001\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<table class=\"medsbase-spec-table\" style=\"width: 100%; border-collapse: collapse; margin: 18px 0; font-size: 14px;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 8px 12px; text-align: left; width: 30%;\">\u4ed5\u69d8<\/th>\n<th style=\"padding: 8px 12px; text-align: left;\">\u8a73\u7d30<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>CAS\u756a\u53f7<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">1208243-50-8\uff08\u30b7\u30d3\u30cd\u30c1\u30c9\uff09<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u30bf\u30a4\u30d7<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u9020\u8840\u4f5c\u7528\u306e\u306a\u3044\u3001\u30d2\u30c8\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\uff08EPO\uff09\u306e\u30d8\u30ea\u30c3\u30af\u30b9B\u306b\u7531\u6765\u3059\u308b11\u30a2\u30df\u30ce\u9178\u5408\u6210\u30da\u30d7\u30c1\u30c9\uff08Helix B Surface Peptide, HBSP\uff09\uff1b\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08IRR\uff09\u30a2\u30b4\u30cb\u30b9\u30c8\uff1b\u958b\u767a\u30b3\u30fc\u30c9\uff1aARA-290\uff0f\u30b7\u30d3\u30cd\u30c1\u30c9\uff08Araim Pharmaceuticals\uff09<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u5206\u5b50\u5f0f<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">C<sub>51<\/sub>H<sub>84<\/sub>N<sub>16<\/sub>O<sub>21<\/sub><\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u5206\u5b50\u91cf<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">~1,257.4 Da<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u914d\u5217<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">H-pyroGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH\uff08pyrEEQLERALNSS\uff09\u2014 \u30d2\u30c8\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u30d8\u30ea\u30c3\u30af\u30b9B\u306e\u6c34\u76f8\u9732\u51fa\u9762\u306b\u76f8\u5f53\u3059\u308b\u76f4\u9396\u72b611\u6b8b\u57fa\u914d\u5217\u3002N\u672b\u7aef\u306e\u30b0\u30eb\u30bf\u30df\u30f3\u306f\u81ea\u767a\u7684\u306b\u30d4\u30ed\u30b0\u30eb\u30bf\u30df\u30f3\u9178\u306b\u74b0\u5316\u3057\u307e\u3059\uff08\u516c\u8868\u3055\u308c\u3066\u3044\u308b\u5206\u5b50\u91cf1,257.4 Da\u3068\u4e00\u81f4\uff09\u3002C\u672b\u7aef\u306f\u904a\u96e2\u9178\u3067\u3042\u308a\u3001\u30b8\u30b9\u30eb\u30d5\u30a3\u30c9\u7d50\u5408\u3001\u8102\u80aa\u9178\u30a2\u30b7\u30eb\u5316\u3001PEG\u5316\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u5f62\u614b<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u51cd\u7d50\u4e7e\u71e5\u7c89\u672b\uff08\u767d\u8272\u301c\u5fae\u9ec4\u8272\uff09<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u7d14\u5ea6<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u226599%\uff08HPLC\u691c\u8a3c\u6e08\u307f\u3001COA\u306f\u3054\u8981\u671b\u306b\u5fdc\u3058\u3066\u63d0\u4f9b\uff09<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u4fdd\u7ba1\u65b9\u6cd5<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u51cd\u7d50\u4e7e\u71e5\u54c1\uff1a\u30ef\u30fc\u30ad\u30f3\u30b0\u30b9\u30c8\u30c3\u30af\u306f2\uff5e8\u00b0C\uff08\u51b7\u8535\u5eab\uff09\u3001\u672a\u958b\u5c01\u30d0\u30a4\u30a2\u30eb\u306e\u9577\u671f\u4fdd\u5b58\u306f\u221220\u00b0C\u3002\u518d\u6eb6\u89e3\u5f8c\uff1a2\uff5e8\u00b0C\u3001\u7d0414\uff5e28\u65e5\u4ee5\u5185\u306b\u4f7f\u7528\u3002\u5149\u304b\u3089\u4fdd\u8b77\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u518d\u6eb6\u89e3\u6db2\u306e\u51cd\u7d50\u878d\u89e3\u306e\u7e70\u308a\u8fd4\u3057\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u6eb6\u89e3\u6027<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u9759\u83cc\u6c34\uff08\u63a8\u5968\uff09\u307e\u305f\u306f\u6ec5\u83cc\u6c34\u3002\u6eb6\u89e3\u6027\u304c\u9ad8\u304f\u3001\u672a\u4fee\u98fe\u306e11\u91cf\u4f53\u306f\u7a4f\u3084\u304b\u306b\u6e26\u5dfb\u304d\u652a\u62cc\u3059\u308b\u3053\u3068\u3067\u901f\u3084\u304b\u306b\u6eb6\u89e3\u3057\u307e\u3059\u3002<\/td>\n<\/tr>\n<tr style=\"background: #fff;\">\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0; width: 30%;\"><strong>\u7814\u7a76\u7528\u9014<\/strong><\/td>\n<td style=\"padding: 8px 12px; border-bottom: 1px solid #e0e0e0;\">\u5b9f\u9a13\u5ba4\u7814\u7a76\u7528\u306e\u307f\u3067\u3059\u3002\u30d2\u30c8\u307e\u305f\u306f\u52d5\u7269\u306e\u8a3a\u65ad\u30fb\u6cbb\u7642\u76ee\u7684\u306b\u306f\u4f7f\u7528\u3057\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><!-- \/medsbase-tldr-answer --><\/p>\n<h2>ARA-290\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h2>\n<p><strong>ARA-290<\/strong> \uff08cibinetide\uff09\u306f\u3001\u30d2\u30c8\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\uff08EPO\uff09\u306e\u30d8\u30ea\u30c3\u30af\u30b9B\u306e\u6c34\u6eb6\u6027\u9732\u51fa\u9762\u306b\u5bfe\u5fdc\u3059\u308b11\u30a2\u30df\u30ce\u9178\u306e\u76f4\u9396\u72b6\u5408\u6210\u30da\u30d7\u30c1\u30c9\u3067\u3059\u3002\u3053\u308c\u306f\u3001\u53e4\u5178\u7684\u306a\u30db\u30e2\u4e8c\u91cf\u4f53EPO\u53d7\u5bb9\u4f53\uff08EPOR<sub>2<\/sub>\uff09\u304c\u8d64\u8840\u7403\u7523\u751f\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002ARA-290\u306f\u3001Araim Pharmaceuticals\u306eMichael Brines\u3068Anthony Cerami\u306b\u3088\u3063\u3066\u5408\u7406\u7684\u306b\u8a2d\u8a08\u3055\u308c\u3001\u6b74\u53f2\u7684\u306b\u5358\u4e00\u5206\u5b50\u306b\u7d61\u307f\u5408\u3063\u3066\u3044\u305f2\u3064\u306e\u85ac\u7406\u5b66\u7684\u306b\u7570\u306a\u308bEPO\u6d3b\u6027\u3092\u5206\u96e2\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u307e\u3057\u305f\uff1a <strong>\u8d64\u8840\u7403\u751f\u6210<\/strong> \uff08\u8840\u6813\u585e\u6813\u75c7\u306e\u30ea\u30b9\u30af\u304c\u3042\u308b\u305f\u3081\u7d44\u7e54\u4fdd\u8b77\u85ac\u3068\u3057\u3066\u306eEPO\u306e\u4f7f\u7528\u3092\u5236\u9650\u3059\u308b\u30d8\u30de\u30c8\u30af\u30ea\u30c3\u30c8\u4e0a\u6607\u4f5c\u7528\uff09\u3068 <strong>\u7d44\u7e54\u4fdd\u8b77<\/strong> \uff08\u7570\u306a\u308b\u30d8\u30c6\u30ed\u30de\u30fc\u53d7\u5bb9\u4f53\u3092\u4ecb\u3057\u305f\u6297\u708e\u75c7\u3001\u6297\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3001\u304a\u3088\u3073\u4fee\u5fa9\u4fc3\u9032\u4f5c\u7528\uff09\u3002<\/p>\n<p>\u30da\u30d7\u30c1\u30c9\u914d\u5217\u3092\u30d8\u30ea\u30c3\u30af\u30b9B\u8868\u9762\u306b\u5236\u9650\u3059\u308b\u3053\u3068\u3067\u3001ARA-290\u304c\u89aa\u548c\u6027\u3092\u4fdd\u6301\u3059\u308b\u306e\u306f\u3001 <strong>\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08IRR\uff09<\/strong> \u2014 EPO\u53d7\u5bb9\u4f53\uff08EPOR\uff09\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3068\u03b2\u5171\u901a\u53d7\u5bb9\u4f53\uff08\u03b2cR\u3001CD131\uff1bGM-CSF\u3001IL-3\u3001IL-5\u53d7\u5bb9\u4f53\u306e\u5171\u6709\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\uff09\u304b\u3089\u306a\u308b\u30d8\u30c6\u30ed\u8907\u5408\u4f53\u3067\u3042\u308a\u3001EPOR\u3078\u306e\u7d50\u5408\u3092\u6d88\u5931\u3055\u305b\u307e\u3059<sub>2<\/sub> \u8d64\u8840\u7403\u9020\u8840\u3092\u62c5\u3046\u30db\u30e2\u4e8c\u91cf\u4f53\u3067\u3059\u3002\u305d\u306e\u7d50\u679c\u5f97\u3089\u308c\u308b\u30da\u30d7\u30c1\u30c9\u306f\u3001\u30d8\u30de\u30c8\u30af\u30ea\u30c3\u30c8\u3092\u4e0a\u6607\u3055\u305b\u308b\u3053\u3068\u306a\u304f\u3001\u307e\u305f\u6cbb\u7642\u7528EPO\u306e\u4f7f\u7528\u3092\u5236\u9650\u3059\u308b\u8840\u6813\u585e\u6813\u75c7\u3084\u9ad8\u8840\u5727\u306e\u30ea\u30b9\u30af\u3092\u4f34\u3046\u3053\u3068\u306a\u304f\u3001\u7d44\u7e54\u5185\u3067EPO\u306e\u7d30\u80de\u4fdd\u8b77\u4f5c\u7528\u3001\u6297\u708e\u75c7\u4f5c\u7528\u3001\u795e\u7d4c\u4fdd\u8b77\u4f5c\u7528\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n<p>ARA-290\u306e\u8840\u6f3f\u4e2d\u534a\u6e1b\u671f\u306f\u7d042\u5206\u3068\u77ed\u304f\u3001\u5206\u5b50\u306f\u901f\u3084\u304b\u306b\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u3055\u308c\u307e\u3059\u304c\u3001\u751f\u7269\u5b66\u7684\u52b9\u679c\u306f\u4e0b\u6d41\u306e\u7d30\u80de\u4fdd\u8b77\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30ab\u30b9\u30b1\u30fc\u30c9\uff08JAK2\/STAT3\u3001PI3K\/Akt\u3001\u6297\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9Bcl-2\u30d5\u30a1\u30df\u30ea\u30fc\u306e\u30a2\u30c3\u30d7\u30ec\u30ae\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\uff09\u306e\u6d3b\u6027\u5316\u3092\u901a\u3058\u306624\uff5e72\u6642\u9593\u6301\u7d9a\u3057\u307e\u3059\u3002\u3053\u306e\u85ac\u7269\u52d5\u614b\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3001\u52b9\u679c\u306e\u6301\u7d9a\u6642\u9593\u304c\u6301\u7d9a\u7684\u306a\u8840\u6f3f\u4e2d\u6fc3\u5ea6\u3067\u306f\u306a\u304f\u3001\u30b7\u30b0\u30ca\u30eb\u30ab\u30b9\u30b1\u30fc\u30c9\u306e\u52d5\u614b\u306b\u3088\u3063\u3066\u6c7a\u5b9a\u3055\u308c\u308b\u53d7\u5bb9\u4f53\u30c8\u30ea\u30ac\u30fc\u30da\u30d7\u30c1\u30c9\u306b\u7279\u5fb4\u7684\u306a\u3082\u306e\u3067\u3059\u3002ARA-290\u306f <strong>\u30aa\u30fc\u30d5\u30a1\u30f3\u30c9\u30e9\u30c3\u30b0\u6307\u5b9a\uff08\u5e0c\u5c11\u75be\u75c5\u7528\u533b\u85ac\u54c1\u6307\u5b9a\uff09<\/strong> \u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u306b\u95a2\u9023\u3059\u308b\u5c0f\u5f84\u7dda\u7dad\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3001\u7c73\u56fd\u304a\u3088\u3073\u6b27\u5dde\u9023\u5408\u306b\u304a\u3044\u3066\u53d6\u5f97\u3057\u3066\u304a\u308a\u3001\u7cd6\u5c3f\u75c5\u6027\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u304a\u3088\u3073\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u95a2\u9023\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\u306b\u95a2\u3059\u308b\u8907\u6570\u306e\u7b2c2\u76f8\u81e8\u5e8a\u8a66\u9a13\u3067\u8a55\u4fa1\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002FDA\u3001EMA\u3001MHRA\u3001\u307e\u305f\u306f\u305d\u306e\u4ed6\u306e\u4e3b\u8981\u306a\u898f\u5236\u5f53\u5c40\u306b\u3088\u308b <strong>\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u305b\u3093<\/strong> \u30d2\u30c8\u6cbb\u7642\u7528\u9014\u306e\u627f\u8a8d\u306f\u53d7\u3051\u3066\u3044\u307e\u305b\u3093\u3002\u3053\u3053\u3067\u8ca9\u58f2\u3055\u308c\u3066\u3044\u308b\u7814\u7a76\u30b0\u30ec\u30fc\u30c9\u306eARA-290\u306f\u4f9b\u7d66\u3055\u308c\u307e\u3059 <strong>\u7814\u7a76\u5ba4\u7814\u7a76\u7528\u306e\u307f\u3067\u3059<\/strong> \u30d2\u30c8\u307e\u305f\u306f\u52d5\u7269\u3078\u306e\u6295\u4e0e\u3092\u76ee\u7684\u3068\u3057\u305f\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<h2>\u4f5c\u7528\u6a5f\u5e8f \u2014 \u8d64\u8840\u7403\u9020\u8840\u3092\u4f34\u308f\u306a\u3044\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\u30a2\u30b4\u30cb\u30ba\u30e0<\/h2>\n<p>ARA-290\u306e\u85ac\u7406\u5b66\u7684\u7279\u5fb4\u306f\u3001\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u306e\u8d64\u8840\u7403\u9020\u8840\u7d4c\u8def\u3092\u8fc2\u56de\u3057\u3064\u3064\u3001\u7d30\u80de\u4fdd\u8b77\u7d4c\u8def\u3092\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u516c\u8868\u3055\u308c\u305f\u7814\u7a76\u3067\u306f\u3001\u4ee5\u4e0b\u306e3\u3064\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<ul>\n<li><strong>\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08IRR\uff09\u30a2\u30b4\u30cb\u30ba\u30e0 \u2014 EPOR + \u03b2cR \/ CD131\u30d8\u30c6\u30ed\u8907\u5408\u4f53<\/strong> \u2014 \u708e\u75c7\u307e\u305f\u306f\u4f4e\u9178\u7d20\u640d\u50b7\u6761\u4ef6\u4e0b\u3067\u306f\u3001\u7d44\u7e54\u7d30\u80de\u306f\u30d9\u30fc\u30bf\u5171\u901a\u53d7\u5bb9\u4f53\uff08\u03b2cR\u3001CD131\uff09\u3092\u30a2\u30c3\u30d7\u30ec\u30ae\u30e5\u30ec\u30fc\u30c8\u3057\u3001EPO\u53d7\u5bb9\u4f53\uff08EPOR\uff09\u3068\u306e\u30d8\u30c6\u30ed\u8907\u5408\u4f53\u3092\u5f62\u6210\u3057\u307e\u3059\u3002\u3053\u306eIRR\u30d8\u30c6\u30ed\u8907\u5408\u4f53\u304cARA-290\u306e\u5206\u5b50\u6a19\u7684\u3067\u3059\u3002\u7d50\u5408\u306b\u3088\u308aJAK2\u306e\u30ea\u30f3\u9178\u5316\u3068\u4e0b\u6d41\u306eSTAT3 \/ STAT5 \/ PI3K-Akt\u306e\u6d3b\u6027\u5316\u304c\u5f15\u304d\u8d77\u3053\u3055\u308c\u3001\u6297\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u30bf\u30f3\u30d1\u30af\u8cea\uff08Bcl-2\u3001Bcl-xL\uff09\u306e\u30a2\u30c3\u30d7\u30ec\u30ae\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u7523\u751f\uff08TNF-\u03b1\u3001IL-1\u03b2\u3001IL-6\uff09\u306e\u6291\u5236\u3001\u304a\u3088\u3073\u7d44\u7e54\u4fee\u5fa9\u30d7\u30ed\u30b0\u30e9\u30e0\u306e\u52d5\u54e1\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002IRR\u306f\u69cb\u6210\u7684\u306b\u767a\u73fe\u3055\u308c\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u640d\u50b7\u3084\u708e\u75c7\u306e\u90e8\u4f4d\u3067\u5c40\u6240\u7684\u306b\u30a2\u30c3\u30d7\u30ec\u30ae\u30e5\u30ec\u30fc\u30c8\u3055\u308c\u308b\u305f\u3081\u3001ARA-290\u306f\u3001\u5fc5\u8981\u306a\u5834\u6240\u3067\u7279\u7570\u7684\u306b\u4fee\u5fa9\u30b7\u30b0\u30ca\u30eb\u3092\u6d3b\u6027\u5316\u3059\u308b\u3001\u72b6\u6cc1\u4f9d\u5b58\u7684\u30a2\u30b4\u30cb\u30b9\u30c8\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u30db\u30e2\u4e8c\u91cf\u4f53EPOR\u3078\u306e\u7d50\u5408\u306a\u3057<sub>2<\/sub> \u2014 \u8d64\u8840\u7403\u9020\u8840\u306a\u3057<\/strong> \u2014 \u9aa8\u9ac4\u8d64\u8840\u7403\u524d\u99c6\u7d30\u80de\u4e0a\u306e\u53e4\u5178\u7684\u306a\u8d64\u8840\u7403\u9020\u8840\u53d7\u5bb9\u4f53\u306f\u3001CD131\u306e\u95a2\u4e0e\u304c\u306a\u30442\u3064\u306eEPOR\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u304b\u3089\u306a\u308b\u30db\u30e2\u4e8c\u91cf\u4f53\u3067\u3059\u3002ARA-290\u306f\u3053\u306e\u30db\u30e2\u4e8c\u91cf\u4f53\u306b\u5bfe\u3057\u3066\u7121\u8996\u3067\u304d\u308b\u7a0b\u5ea6\u306e\u89aa\u548c\u6027\u3057\u304b\u6301\u305f\u305a\u3001\u305d\u306e\u305f\u3081\u3001\u81e8\u5e8a\u8a66\u9a13\u3067\u306e\u53cd\u5fa9\u6295\u4e0e\u306b\u304a\u3044\u3066\u3082\u3001\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u3001\u30d8\u30de\u30c8\u30af\u30ea\u30c3\u30c8\u3001\u307e\u305f\u306f\u7db2\u72b6\u8d64\u8840\u7403\u6570\u306b\u691c\u51fa\u53ef\u80fd\u306a\u5909\u5316\u306f\u751f\u3058\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u3001ARA-290\u3092\u5b8c\u5168\u9577EPO\u3084\u8d64\u8840\u7403\u9020\u8840\u6d3b\u6027\u3092\u4fdd\u6301\u3057\u3066\u3044\u305f\u521d\u671f\u306e\u6539\u5909\u578bEPO\u985e\u4f3c\u4f53\uff08\u30c0\u30eb\u30d9\u30dd\u30a8\u30c1\u30f3\u3001CERA\uff09\u3068\u533a\u5225\u3059\u308b\u4e2d\u5fc3\u7684\u306a\u8a2d\u8a08\u4e0a\u306e\u7279\u5fb4\u3067\u3059\u3002<\/li>\n<li><strong>\u4e0b\u6d41\u306e\u6297\u708e\u75c7\u4f5c\u7528\u304a\u3088\u3073\u7d44\u7e54\u4fee\u5fa9\u52b9\u679c<\/strong> \u2014 \u524d\u81e8\u5e8a\u304a\u3088\u3073\u81e8\u5e8a\u7814\u7a76\u306b\u304a\u3044\u3066\u3001ARA-290\u306f\u6d3b\u6027\u5316\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306b\u3088\u308b\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u7523\u751f\u3092\u6e1b\u5c11\u3055\u305b\u3001\u5c0f\u5f84\u7dda\u7dad\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\u30b9\u30b3\u30a2\u3092\u4f4e\u4e0b\u3055\u305b\u3001\u89d2\u819c\u5275\u50b7\u6cbb\u7652\u3092\u4fc3\u9032\u3057\u3001\u814e\u81d3\u304a\u3088\u3073\u5fc3\u81d3\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u865a\u8840\u518d\u704c\u6d41\u969c\u5bb3\u3092\u8efd\u6e1b\u3057\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u524d\u81e8\u5e8a\u30e2\u30c7\u30eb\u306b\u304a\u3044\u3066\u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u6539\u5584\u3057\u307e\u3059\u3002\u3053\u306e\u52b9\u679c\u306e\u5e83\u7bc4\u3055\u306f\u3001\u7d44\u7e54\u7279\u7570\u7684\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u306f\u306a\u304f\u3001\u708e\u75c7\u72b6\u614b\u4e0b\u3067\u306eIRR\u306e\u5e83\u7bc4\u306a\u7d44\u7e54\u5206\u5e03\u3092\u53cd\u6620\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<p>\u77ed\u3044\u8840\u6f3f\u4e2d\u534a\u6e1b\u671f\uff08\u7d042\u5206\uff09\u3068\u6301\u7d9a\u7684\u306a\u751f\u7269\u5b66\u7684\u52b9\u679c\uff0824\uff5e72\u6642\u9593\uff09\u306e\u7d44\u307f\u5408\u308f\u305b\u306f\u3001ARA-290\u306e\u7814\u7a76\u30d7\u30ed\u30c8\u30b3\u30eb\u304c\u3001\u5206\u5b50\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u304c\u8fc5\u901f\u3067\u3042\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u901a\u5e38\u3001\u6bce\u65e5\u307e\u305f\u306f\u9694\u65e5\u306e\u6295\u4e0e\u3092\u63a1\u7528\u3059\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002\u85ac\u529b\u5b66\u7684\u6301\u7d9a\u6642\u9593\u306f\u3001\u8840\u6f3f\u4e2d\u6ede\u7559\u6642\u9593\u3067\u306f\u306a\u304f\u3001\u4e0b\u6d41\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30ab\u30b9\u30b1\u30fc\u30c9\u306b\u3088\u3063\u3066\u8a2d\u5b9a\u3055\u308c\u308b\u304b\u3089\u3067\u3059\u3002\u76ae\u4e0b\u6295\u4e0e\u306f\u6a19\u6e96\u7684\u306a\u7814\u7a76\u6295\u4e0e\u7d4c\u8def\u3067\u3042\u308a\u3001\u81e8\u5e8a\u958b\u767a\u3067\u4f7f\u7528\u3055\u308c\u305f\u7d4c\u8def\u3067\u3059\u3002<\/p>\n<h2>\u516c\u8868\u3055\u308c\u305f\u7814\u7a76\u7528\u9014<\/h2>\n<p>ARA-290\u306f\u3001\u4ee5\u4e0b\u306e\u7814\u7a76\u3092\u76ee\u7684\u3068\u3057\u305f\u5b9f\u9a13\u5ba4\u7814\u7a76\u3067\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\uff1a<\/p>\n<ul>\n<li><strong>\u7cd6\u5c3f\u75c5\u6027\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u304a\u3088\u3073\u5c0f\u5f84\u7dda\u7dad\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u306e\u7814\u7a76<\/strong> \u2014 \u89d2\u819c\u795e\u7d4c\u7dda\u7dad\u5bc6\u5ea6\u8a55\u4fa1\u3001\u8868\u76ae\u5185\u795e\u7d4c\u7dda\u7dad\u5bc6\u5ea6\uff08IENFD\uff09\u3001\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\u30b9\u30b3\u30a2\u30ea\u30f3\u30b0\uff1b\u4e3b\u8981\u306a\u81e8\u5e8a\u7814\u7a76\u9069\u5fdc\u3067\u3042\u308a\u30012\u578b\u7cd6\u5c3f\u75c5\u6027\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2c2\u76f8\u8a66\u9a13\u3067\u306f\u3001\u795e\u7d4c\u7dda\u7dad\u518d\u751f\u3068\u75bc\u75db\u30b9\u30b3\u30a2\u306e\u6539\u5584\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li><strong>\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u95a2\u9023\u5c0f\u5f84\u7dda\u7dad\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc<\/strong> \u2014 ARA-290\u304c\u7c73\u56fd\u304a\u3088\u3073EU\u3067\u5e0c\u5c11\u75be\u75c5\u7528\u533b\u85ac\u54c1\u6307\u5b9a\u3092\u53d7\u3051\u3066\u3044\u308b\u9069\u5fdc\u75c7\uff1b\u8089\u82bd\u816b\u6027\u708e\u75c7\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u524d\u81e8\u5e8a\u304a\u3088\u3073\u7b2c2\u76f8\u7814\u7a76<\/li>\n<li><strong>\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\u306e\u7814\u7a76<\/strong> \u2014 \u5316\u5b66\u7642\u6cd5\u8a98\u767a\u6027\u672b\u68a2\u795e\u7d4c\u969c\u5bb3\u3001\u8853\u5f8c\u795e\u7d4c\u969c\u5bb3\u3001IRR\u4ecb\u5728\u6027\u75bc\u75db\u7d4c\u8def\u306e\u6a5f\u69cb\u89e3\u660e<\/li>\n<li><strong>\u865a\u8840\u518d\u704c\u6d41\u969c\u5bb3\u306e\u7814\u7a76<\/strong> \u2014 \u814e\u3001\u5fc3\u81d3\u3001\u8133\u306e\u865a\u8840\u518d\u704c\u6d41\u30e2\u30c7\u30eb\uff1b\u6297\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u4f5c\u7528\u304a\u3088\u3073\u6297\u708e\u75c7\u4f5c\u7528\u306e\u7279\u6027\u8a55\u4fa1<\/li>\n<li><strong>\u708e\u75c7\u304a\u3088\u3073\u81ea\u7136\u514d\u75ab\u306e\u7814\u7a76<\/strong> \u2014 \u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u6975\u6027\u5316\u3001\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u6291\u5236\u30a2\u30c3\u30bb\u30a4\u3001IRR\u4f9d\u5b58\u7684 vs IRR\u975e\u4f9d\u5b58\u7684\u30b7\u30b0\u30ca\u30eb\u89e3\u6790<\/li>\n<li><strong>2\u578b\u7cd6\u5c3f\u75c5\u306e\u4ee3\u8b1d\u7814\u7a76<\/strong> \u2014 \u8840\u7cd6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u03b2\u7d30\u80de\u4fdd\u8b77\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u306e\u6bd4\u8f03<\/li>\n<li><strong>\u89d2\u819c\u5275\u50b7\u6cbb\u7652\u304a\u3088\u3073\u773c\u79d1\u7814\u7a76<\/strong> \u2014 \u89d2\u819c\u4e0a\u76ae\u5275\u50b7\u9589\u9396\u901f\u5ea6\u3001\u89d2\u819c\u306b\u304a\u3051\u308b\u795e\u7d4c\u7dda\u7dad\u306e\u518d\u751f\uff08\u6700\u3082\u5bc6\u306b\u795e\u7d4c\u652f\u914d\u3055\u308c\u308b\u7d44\u7e54\u306e\u4e00\u3064\u3067\u3001IRR\u99c6\u52d5\u578b\u4fee\u5fa9\u306e\u92ed\u654f\u306a\u30a2\u30a6\u30c8\u30d7\u30c3\u30c8\uff09<\/li>\n<\/ul>\n<p>\u95a2\u9023\u3059\u308b\u6297\u708e\u75c7\u304a\u3088\u3073\u7d44\u7e54\u4fee\u5fa9\u306e\u7814\u7a76\u7528\u30da\u30d7\u30c1\u30c9\u306b\u3064\u3044\u3066\u3001\u3088\u308a\u5e83\u3044\u6587\u8108\u3092\u304a\u6c42\u3081\u306e\u5834\u5408\u306f\u3001\u4ee5\u4e0b\u3092\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\u3002 <a href=\"https:\/\/medsbase.com\/ja\/bpc-157\/\">BPC-157<\/a> (\u80c3\u30da\u30d7\u30c1\u30c9\u7531\u6765\u306eMSK\/GI\u7d44\u7e54\u4fee\u5fa9), <a href=\"https:\/\/medsbase.com\/ja\/tb-500\/\">TB-500<\/a> (Thymosin Beta-4\u65ad\u7247\u3001\u5e83\u7bc4\u306a\u7d44\u7e54\u4fee\u5fa9) <a href=\"https:\/\/medsbase.com\/ja\/kpv-lysine-proline-valine\/\">KPV<\/a> (\u03b1-MSH\u7531\u6765\u306e\u6297\u708e\u75c7\u30c8\u30ea\u30da\u30d7\u30c1\u30c9)\u3002\u3059\u3079\u3066\u3092\u8868\u793a <a href=\"https:\/\/medsbase.com\/ja\/peptides\/\">\u7814\u7a76\u7528\u30da\u30d7\u30c1\u30c9\u30ab\u30bf\u30ed\u30b0<\/a> \u5316\u5408\u7269\u9078\u629e\u306e\u305f\u3081\u306b\u3002<\/p>\n<h2>\u5229\u7528\u53ef\u80fd\u306a\u529b\u4fa1\u3068\u6fc3\u5ea6<\/h2>\n<p>MedsBase\u3067\u306f\u3001ARA-290\uff0810 mg\u51cd\u7d50\u4e7e\u71e5\u30d0\u30a4\u30a2\u30eb\uff09\u3092\u3001\u4e00\u822c\u7684\u306a\u7814\u7a76\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u5408\u308f\u305b\u3066\u3054\u7528\u610f\u3057\u3066\u304a\u308a\u307e\u3059\u300210\u30d0\u30a4\u30a2\u30eb\u307e\u305f\u306f20\u30d0\u30a4\u30a2\u30eb\u306e\u30d1\u30c3\u30af\u5f62\u5f0f\u3067\u3001\u518d\u6eb6\u89e3\u306b\u95a2\u3059\u308b\u5b8c\u5168\u306a\u30ac\u30a4\u30c0\u30f3\u30b9\u4ed8\u304d\u3067\u5165\u624b\u53ef\u80fd\u3067\u3059\u3002<\/p>\n<table style=\"width: 100%; border-collapse: collapse; margin: 16px 0;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">\u30d0\u30a4\u30a2\u30eb\u529b\u4fa1<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">\u5178\u578b\u7684\u306a\u7814\u7a76\u4f7f\u7528\u4f8b<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">\u30d1\u30c3\u30af\u30b5\u30a4\u30ba<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>10 mg<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u6a19\u6e96\u7814\u7a76\u6fc3\u5ea6 \u2014 \u7cd6\u5c3f\u75c5\u6027\u795e\u7d4c\u969c\u5bb3\u3001\u865a\u8840\u518d\u704c\u6d41\u3001\u89d2\u819c\u4fee\u5fa9\u3001\u708e\u75c7\u306e\u5404\u30e2\u30c7\u30eb\u3067\u8907\u6570\u9031\u306e\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u5bfe\u5fdc\u3002mg\u5f53\u305f\u308a\u306e\u30b3\u30b9\u30c8\u304c\u6700\u3082\u4f4e\u3044\u3002<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">10\u307e\u305f\u306f20\u30d0\u30a4\u30a2\u30eb<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u516c\u8868\u3055\u308c\u305f\u8a66\u9a13\u306b\u304a\u3051\u308b\u81e8\u5e8a\u7b2c2\u76f8\u7528\u91cf\u306f\u3001\u7cd6\u5c3f\u75c5\u6027\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u304a\u3088\u3073\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9\u95a2\u9023\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u306b\u5bfe\u3057\u3066\u30011\u65e51\u56de4 mg\u3092\u76ae\u4e0b\u6295\u4e0e\u3059\u308b\u3082\u306e\u3067\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u7814\u7a76\u7528\u306e10 mg\u30d0\u30a4\u30a2\u30eb1\u672c\u306f\u3001\u751f\u4f53\u5185\u7814\u7a76\u306b\u304a\u3051\u308b\u81e8\u5e8a\u76f8\u5f53\u91cf\u306e\u8907\u6570\u65e5\u5206\u306e\u4f9b\u7d66\u306b\u76f8\u5f53\u3057\u307e\u3059\u3002ARA-290\u306f\u4fee\u98fe\u306e\u306a\u3044\u76f4\u9396\u72b611\u30a2\u30df\u30ce\u9178\u30da\u30d7\u30c1\u30c9\u3068\u3057\u3066\u4f9b\u7d66\u3055\u308c\u3066\u304a\u308a\u3001\u30a2\u30b7\u30eb\u9396\u3001PEG\u5316\u3001\u30b8\u30b9\u30eb\u30d5\u30a3\u30c9\u7d50\u5408\u306f\u4e00\u5207\u306a\u304f\u3001\u3088\u308a\u9577\u3044\u30da\u30d7\u30c1\u30c9\u3084\u4fee\u98fe\u30da\u30d7\u30c1\u30c9\u306b\u6bd4\u3079\u3066\u518d\u6eb6\u89e3\u304c\u5bb9\u6613\u3067\u3059\u3002<\/p>\n<h2>\u6bd4\u8f03\u306e\u30dd\u30a4\u30f3\u30c8 \u2014 ARA-290 vs BPC-157<\/h2>\n<p>ARA-290 \u3068 <a href=\"https:\/\/medsbase.com\/ja\/bpc-157\/\">BPC-157<\/a> \u306f\u3001\u3069\u3061\u3089\u3082\u7d44\u7e54\u4fee\u5fa9\u304a\u3088\u3073\u6297\u708e\u75c7\u7814\u7a76\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u30892\u3064\u306e\u30da\u30d7\u30c1\u30c9\u306f\u307e\u3063\u305f\u304f\u7570\u306a\u308b\u5206\u5b50\u6a5f\u69cb\u3092\u6a19\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002ARA-290\u306fEPO\u7531\u6765\u306e\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\u30a2\u30b4\u30cb\u30b9\u30c8\u3067\u3001JAK2\/STAT3\u306e\u7d30\u80de\u4fdd\u8b77\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u99c6\u52d5\u3057\u307e\u3059\u3002BPC-157\u306f\u3001\u30d2\u30c8\u80c3\u6db2\u30bf\u30f3\u30d1\u30af\u8ceaBPC\u306e\u65ad\u7247\u306b\u7531\u6765\u3059\u308b15\u30a2\u30df\u30ce\u9178\u306e\u5408\u6210\u5b89\u5b9a\u6027\u80c3\u30da\u30f3\u30bf\u30c7\u30ab\u30da\u30d7\u30c1\u30c9\u3067\u3001\u4e00\u9178\u5316\u7a92\u7d20\u5408\u6210\u9175\u7d20\u8abf\u7bc0\u3001VEGF\u30a2\u30c3\u30d7\u30ec\u30ae\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u3001\u6210\u9577\u56e0\u5b50\u53d7\u5bb9\u4f53\u30af\u30ed\u30b9\u30c8\u30fc\u30af\u306a\u3069\u3001\u8907\u96d1\u306a\u591a\u7d4c\u8def\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u901a\u3058\u3066\u4f5c\u7528\u3057\u307e\u3059\u3002<\/p>\n<table style=\"width: 100%; border-collapse: collapse; margin: 16px 0;\">\n<thead>\n<tr style=\"background: #2c7cb0; color: #fff;\">\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">\u8a55\u4fa1\u9805\u76ee<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">ARA-290<\/th>\n<th style=\"padding: 10px; border: 1px solid #ddd; text-align: left;\">BPC-157<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u7531\u6765<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u30d2\u30c8\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u306e\u30d8\u30ea\u30c3\u30af\u30b9B\uff08HBSP\uff09<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u30d2\u30c8\u80c3\u6db2\u30bf\u30f3\u30d1\u30af\u8ceaBPC\u306e\u65ad\u7247<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u30a2\u30df\u30ce\u9178\u6570<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">11\u30a2\u30df\u30ce\u9178<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">15\u30a2\u30df\u30ce\u9178<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u53d7\u5bb9\u4f53\uff0f\u6a19\u7684<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08EPOR\uff0b\u03b2cR\uff0fCD131\uff09<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u8907\u6570\u306e\u7d4c\u8def\uff1aNO\u5408\u6210\u9175\u7d20\u3001VEGF\u3001\u6210\u9577\u56e0\u5b50\u306e\u30af\u30ed\u30b9\u30c8\u30fc\u30af<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u4e3b\u306a\u7814\u7a76\u5bfe\u8c61\u7d44\u7e54<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u672b\u68a2\u795e\u7d4c\u3001\u89d2\u819c\u3001\u865a\u8840\u7d44\u7e54\u3001\u708e\u75c7\u7d44\u7e54<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u8171\u3001\u976d\u5e2f\u3001\u8178\u7c98\u819c\u3001\u7b4b\u8089<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u8d64\u8840\u7403\u7523\u751f\u4fc3\u9032\u52b9\u679c<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u306a\u3057\uff08\u8a2d\u8a08\u4e0a\u306e\u91cd\u8981\u306a\u7279\u5fb4\uff09<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">N\/A\uff08EPO\u7d4c\u8def\u30da\u30d7\u30c1\u30c9\u3067\u306f\u306a\u3044\uff09<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u8840\u6f3f\u4e2d\u534a\u6e1b\u671f<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u7d042\u5206\uff08\u52b9\u679c\u306f24\uff5e72\u6642\u9593\u6301\u7d9a\uff09<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u7d0430\u5206\uff08\u524d\u81e8\u5e8a\u3067\u7d4c\u53e3\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3\u304c\u793a\u5506\uff09<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u81e8\u5e8a\u958b\u767a<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u7b2c2\u76f8\uff08\u7cd6\u5c3f\u75c5\u6027\u30cb\u30e5\u30fc\u30ed\u30d1\u30c1\u30fc\u3001\u30b5\u30eb\u30b3\u30a4\u30c9\u30fc\u30b7\u30b9SFN\uff09\uff1b\u5e0c\u5c11\u75be\u75c5\u7528\u533b\u85ac\u54c1\u6307\u5b9a<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u524d\u81e8\u5e8a\u6bb5\u968e\u306e\u307f\uff08\u4e3b\u8981\u898f\u5236\u5f53\u5c40\u306e\u81e8\u5e8a\u8a66\u9a13\u306a\u3057\uff09<\/td>\n<\/tr>\n<tr style=\"background: #f9f9f9;\">\n<td style=\"padding: 10px; border: 1px solid #ddd;\"><strong>\u4fee\u98fe<\/strong><\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u975e\u4fee\u98fe\u76f4\u9396\u72b611-mer<\/td>\n<td style=\"padding: 10px; border: 1px solid #ddd;\">\u975e\u4fee\u98fe\u76f4\u9396\u72b615-mer\uff08\u5b89\u5b9a\u306a\u9162\u9178\u5869\u307e\u305f\u306f\u30a2\u30eb\u30ae\u30f3\u9178\u5869\uff09<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u795e\u7d4c\u969c\u5bb3\u6027\u75bc\u75db\u3001\u672b\u68a2\u795e\u7d4c\u518d\u751f\u3001\u307e\u305f\u306fIRR\u4ecb\u5728\u6027\u7d30\u80de\u4fdd\u8b77\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u7814\u7a76\u3067\u306f\u3001ARA-290\u304c\u6a19\u7684\u53c2\u7167\u30da\u30d7\u30c1\u30c9\u3067\u3059\u3002\u7b4b\u9aa8\u683c\u7cfb\u306e\u8171\u30fb\u976d\u5e2f\u4fee\u5fa9\u307e\u305f\u306f\u6d88\u5316\u7ba1\u7c98\u819c\u6cbb\u7652\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u7814\u7a76\u3067\u306f\u3001, <a href=\"https:\/\/medsbase.com\/ja\/bpc-157\/\">BPC-157<\/a> \u304c\u3088\u308a\u5e83\u304f\u7814\u7a76\u3055\u308c\u3066\u3044\u308b\u9078\u629e\u80a2\u3067\u3059\u3002\u3053\u308c\u30892\u3064\u306e\u30da\u30d7\u30c1\u30c9\u306f\u3001\u4e2d\u67a2\u795e\u7d4c\u7cfb\/\u672b\u68a2\u795e\u7d4c\u7d44\u7e54\u3068\u7d50\u5408\u7d44\u7e54\u306e\u4e21\u65b9\u306b\u308f\u305f\u308b\u76f8\u88dc\u7684\u306a\u4fee\u5fa9\u7d4c\u8def\u3092\u52d5\u54e1\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u7814\u7a76\u30d7\u30ed\u30c8\u30b3\u30fc\u30eb\u3067\u4f75\u7528\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u4ee5\u4e0b\u3082\u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044 <a href=\"https:\/\/medsbase.com\/ja\/tb-500\/\">TB-500<\/a> \uff08Thymosin Beta-4\u30d5\u30e9\u30b0\u30e1\u30f3\u30c8\u3001\u5e83\u7bc4\u306a\u7d44\u7e54\u4fee\u5fa9\u30d9\u30f3\u30c1\u30de\u30fc\u30af\uff09\u304a\u3088\u3073 <a href=\"https:\/\/medsbase.com\/ja\/kpv-lysine-proline-valine\/\">KPV<\/a> \uff08\u03b1-MSH\u7531\u6765\u6297\u708e\u75c7\u30c8\u30ea\u30da\u30d7\u30c1\u30c9\uff09\u3002<\/p>\n<div style=\"background: #f4f8fb; border-left: 4px solid #2c7cb0; padding: 14px 18px; margin: 18px 0;\"><strong class=\"mb-bac-water-callout\">\ud83d\udca7 BAC\u6c34\u304c\u5fc5\u8981\u3067\u3059\u304b\uff1f<\/strong> \u51cd\u7d50\u4e7e\u71e5\u54c1\u306e\u5fa9\u5143\u306b\u306f\u6ec5\u83cc\u9759\u83cc\u6c34\u304c\u5fc5\u8981\u3067\u3059\u3002\u672c\u88fd\u54c1\u3068\u4f75\u305b\u3066\u5f53\u793e\u306e <a href=\"\/ja\/bac-water\/\"><strong>BAC Water\uff08\u9759\u83cc\u6c34\uff09<\/strong><\/a> \u2014 30 mL\u30de\u30eb\u30c1\u30c9\u30fc\u30ba\u30d0\u30a4\u30a2\u30eb\u30010.9%\u30d9\u30f3\u30b8\u30eb\u30a2\u30eb\u30b3\u30fc\u30eb\u4fdd\u5b58\u3001USP\u30b0\u30ec\u30fc\u30c9\u3002<\/div>\n<h2>\u4fdd\u7ba1\u65b9\u6cd5\u3068\u518d\u6eb6\u89e3<\/h2>\n<p><strong>\u518d\u6eb6\u89e3\u524d\uff1a<\/strong> \u77ed\u671f\u4f7f\u7528\u306e\u30ef\u30fc\u30ad\u30f3\u30b0\u30b9\u30c8\u30c3\u30af\u3068\u3057\u3066\u306f\u3001\u51cd\u7d50\u4e7e\u71e5\u30d0\u30a4\u30a2\u30eb\u3092\u5143\u306e\u5305\u88c5\u306e\u307e\u307e2\uff5e8 \u00b0C\u3067\u51b7\u8535\u4fdd\u5b58\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u672a\u958b\u5c01\u306e\u9577\u671f\u4fdd\u5b58\u306e\u5834\u5408\u306f\u3001\u221220 \u00b0C\u3067\u51cd\u7d50\u4fdd\u5b58\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u51cd\u7d50\u4e7e\u71e5\u72b6\u614b\u306eARA-290\u306f\u3001\u51b7\u8535\u4fdd\u5b58\u3067\u6700\u592724\u304b\u6708\u9593\u3001\u221220 \u00b0C\u3067\u6700\u592736\u304b\u6708\u9593\u5b89\u5b9a\u3067\u3059\u3002\u51cd\u7d50\u4e7e\u71e5\u7c89\u672b\u306e\u51cd\u7d50\u878d\u89e3\u30b5\u30a4\u30af\u30eb\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002ARA-290\u306f\u30b8\u30b9\u30eb\u30d5\u30a3\u30c9\u67b6\u6a4b\u3084\u30a2\u30b7\u30eb\u9396\u3092\u6301\u305f\u306a\u3044\u975e\u4fee\u98fe\u76f4\u9396\u72b6\u30da\u30d7\u30c1\u30c9\u3067\u3042\u308b\u305f\u3081\u3001\u30ab\u30b0\u30ea\u30ea\u30f3\u30c1\u30c9\u3084\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306e\u3088\u3046\u306a\u69cb\u9020\u7684\u306b\u8907\u96d1\u306a\u30da\u30d7\u30c1\u30c9\u3068\u6bd4\u8f03\u3057\u3066\u53d6\u308a\u6271\u3044\u304c\u5bb9\u6613\u3067\u3059\u3002<\/p>\n<p><strong>\u518d\u6eb6\u89e3\u624b\u9806\uff1a<\/strong> \u6ce8\u5c04\u7528\u9759\u83cc\u6c34\u3092\u30d0\u30a4\u30a2\u30eb\u306e\u5074\u58c1\u306b\u6cbf\u3063\u3066\u6ce8\u5165\u3057\u3066\u304f\u3060\u3055\u3044\uff08\u51cd\u7d50\u4e7e\u71e5\u30b1\u30fc\u30ad\u306b\u76f4\u63a5\u304b\u3051\u306a\u3044\u3067\u304f\u3060\u3055\u3044\uff09\u300210 mg\u30d0\u30a4\u30a2\u30eb\u306e\u5834\u5408\u30012.0 mL\u306e\u6ce8\u5c04\u7528\u9759\u83cc\u6c34\u30675 mg\/mL\u306e\u4f5c\u696d\u6fc3\u5ea6\u304c\u5f97\u3089\u308c\u307e\u3059\u30020.08 mL\u3067400 mcg\u304c\u6295\u4e0e\u3055\u308c\uff081 mg\u7528\u91cf\u306b\u306f0.2 mL\u304c\u5fc5\u8981\uff09\u30010.8 mL\u3067\u81e8\u5e8a\u540c\u7b49\u306e4 mg\u7814\u7a76\u7528\u91cf\u304c\u6295\u4e0e\u3055\u308c\u307e\u3059\u3002\u9759\u304b\u306b\u65cb\u56de\u3055\u305b\u3066\u304f\u3060\u3055\u3044\u3002\u6ce1\u7acb\u3061\u306f\u7a7a\u6c17\u3092\u5dfb\u304d\u8fbc\u307f\u30da\u30d7\u30c1\u30c9\u9396\u3092\u5909\u6027\u3055\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u6fc0\u3057\u304f\u632f\u3089\u306a\u3044\u3067\u304f\u3060\u3055\u3044\u3002\u7c89\u672b\u304c\u5b8c\u5168\u306b\u6eb6\u89e3\u3059\u308b\u307e\u3067\u5f85\u3063\u3066\u304b\u3089\uff08ARA-290\u306e\u5834\u5408\u901a\u5e381\u5206\u672a\u6e80\uff09\u5438\u5f15\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u518d\u69cb\u6210\u5f8c\u306f\u3001\u30d0\u30a4\u30a2\u30eb\u30922\uff5e8 \u00b0C\u3067\u4fdd\u5b58\u3057\u300114\uff5e28\u65e5\u4ee5\u5185\u306b\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u5149\u304b\u3089\u4fdd\u8b77\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u6fc1\u308a\u3001\u5fae\u7c92\u5b50\u3001\u307e\u305f\u306f\u8272\u306e\u5909\u5316\u304c\u73fe\u308c\u305f\u5834\u5408\u306f\u5ec3\u68c4\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<h2>\u3088\u304f\u3042\u308b\u8cea\u554f<\/h2>\n<h3>ARA-290\u306fEPO\u985e\u4f3c\u4f53\u3067\u3059\u304b\uff1f\u30d8\u30de\u30c8\u30af\u30ea\u30c3\u30c8\u3092\u4e0a\u6607\u3055\u305b\u307e\u3059\u304b\uff1f<\/h3>\n<p>ARA-290\u306f\u30a8\u30ea\u30b9\u30ed\u30dd\u30a8\u30c1\u30f3\u306e\u30d8\u30ea\u30c3\u30af\u30b9B\u306b\u7531\u6765\u3057\u307e\u3059\u304c\u3001\u7279\u306b <em>\u3057\u307e\u305b\u3093<\/em> \u30d8\u30de\u30c8\u30af\u30ea\u30c3\u30c8\u3092\u4e0a\u6607\u3055\u305b\u306a\u3044\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\u3002EPO\u306e\u53e4\u5178\u7684\u306a\u8d64\u8840\u7403\u9020\u8840\u4f5c\u7528\u306f\u3001\u9aa8\u9ac4\u8d64\u8840\u7403\u524d\u99c6\u7d30\u80de\u4e0a\u306e\u30db\u30e2\u4e8c\u91cf\u4f53EPO\u53d7\u5bb9\u4f53\uff08EPOR<sub>2<\/sub>\uff09\u306b\u3088\u3063\u3066\u5a92\u4ecb\u3055\u308c\u307e\u3059\u3002ARA-290\u306f\u4ee3\u308f\u308a\u306b\u30d8\u30c6\u30ed\u30de\u30fc\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08EPOR + \u03b2cR\/CD131\uff09\u306b\u7d50\u5408\u3057\u3001EPOR\u306b\u5bfe\u3059\u308b\u89aa\u548c\u6027\u306f\u7121\u8996\u3067\u304d\u308b\u7a0b\u5ea6\u3067\u3059<sub>2<\/sub>. \u3002\u516c\u8868\u3055\u308c\u3066\u3044\u308b\u7b2c2\u76f8\u8a66\u9a13\u3067\u306f\u3001\u53cd\u5fa9\u6295\u4e0e\u5f8c\u306b\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u3001\u30d8\u30de\u30c8\u30af\u30ea\u30c3\u30c8\u3001\u7db2\u72b6\u8d64\u8840\u7403\u6570\u306b\u5909\u5316\u306f\u8a8d\u3081\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n<h3>\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08IRR\uff09\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/h3>\n<p>\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\u306f\u3001EPO\u53d7\u5bb9\u4f53\uff08EPOR\uff09\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3068\u30d9\u30fc\u30bf\u5171\u901a\u53d7\u5bb9\u4f53\uff08\u03b2cR\u3001CD131\u3068\u3057\u3066\u3082\u77e5\u3089\u308c\u3001GM-CSF\u3001IL-3\u3001IL-5\u53d7\u5bb9\u4f53\u306e\u5171\u6709\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\uff09\u306e\u30d8\u30c6\u30ed\u8907\u5408\u4f53\u3067\u3059\u3002IRR\u306f\u6052\u5e38\u7684\u306b\u767a\u73fe\u3059\u308b\u306e\u3067\u306f\u306a\u304f\u3001\u30b9\u30c8\u30ec\u30b9\u3092\u53d7\u3051\u305f\u7d44\u7e54\u3001\u640d\u50b7\u3057\u305f\u7d44\u7e54\u3001\u307e\u305f\u306f\u708e\u75c7\u3092\u8d77\u3053\u3057\u305f\u7d44\u7e54\u3067\u5c40\u6240\u7684\u306b\u4e0a\u65b9\u5236\u5fa1\u3055\u308c\u308b\u305f\u3081\u3001ARA-290\u306f\u5168\u8eab\u6027\u30a2\u30b4\u30cb\u30b9\u30c8\u3067\u306f\u306a\u304f\u3001\u72b6\u6cc1\u4f9d\u5b58\u7684\u306b\u7d44\u7e54\u4fee\u5fa9\u30b7\u30b0\u30ca\u30eb\u3068\u3057\u3066\u4f5c\u7528\u3057\u307e\u3059\u3002<\/p>\n<h3>ARA-290\u304c\u30b7\u30d3\u30cd\u30c1\u30c9\u3068\u3082\u547c\u3070\u308c\u308b\u306e\u306f\u306a\u305c\u3067\u3059\u304b\uff1f<\/h3>\n<p>ARA-290\u306f\u3001Araim Pharmaceuticals\uff08\u5f53\u521d\u306e\u958b\u767a\u4f01\u696d\uff09\u306b\u3088\u308a\u4ed8\u4e0e\u3055\u308c\u305f\u958b\u767a\u30b3\u30fc\u30c9\u3067\u3059\u3002\u30b7\u30d3\u30cd\u30c1\u30c9\u306f\u3001\u81e8\u5e8a\u8a66\u9a13\u3084\u898f\u5236\u5f53\u5c40\u306e\u6587\u8108\u3067\u5f8c\u306b\u5272\u308a\u5f53\u3066\u3089\u308c\u305f\u56fd\u969b\u4e00\u822c\u540d\uff08INN\uff09\u3067\u3059\u3002\u3053\u308c\u30892\u3064\u306e\u540d\u79f0\u306f\u3001\u540c\u305811\u30a2\u30df\u30ce\u9178\u30da\u30d7\u30c1\u30c9\uff08CAS\u756a\u53f7 1208243-50-8\uff09\u3092\u6307\u3057\u307e\u3059\u3002<\/p>\n<h3>\u8840\u6f3f\u4e2d\u534a\u6e1b\u671f\u304c\u52b9\u679c\u6301\u7d9a\u6642\u9593\u306b\u6bd4\u3079\u3066\u975e\u5e38\u306b\u77ed\u3044\u306e\u306f\u306a\u305c\u3067\u3059\u304b\uff1f<\/h3>\n<p>ARA-290\u306e\u8840\u6f3f\u4e2d\u534a\u6e1b\u671f\u306f\u7d042\u5206\u3067\u3001\u30da\u30d7\u30c1\u30c9\u306f\u5faa\u74b0\u304b\u3089\u901f\u3084\u304b\u306b\u6d88\u5931\u3057\u307e\u3059\u304c\u3001\u751f\u7269\u5b66\u7684\u52b9\u679c\u306fJAK2\\\/STAT3\u3001PI3K\\\/Akt\u3001\u6297\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u6027Bcl-2\u30d5\u30a1\u30df\u30ea\u30fc\u30b7\u30b0\u30ca\u30eb\u30ab\u30b9\u30b1\u30fc\u30c9\u306e\u4e0b\u6d41\u6d3b\u6027\u5316\u3092\u901a\u3058\u306624\uff5e72\u6642\u9593\u6301\u7d9a\u3057\u307e\u3059\u3002\u3053\u306e\u85ac\u7269\u52d5\u614b\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3001\u52b9\u679c\u6301\u7d9a\u6642\u9593\u304c\u8840\u6f3f\u4e2d\u6fc3\u5ea6\u306e\u6301\u7d9a\u3067\u306f\u306a\u304f\u30b7\u30b0\u30ca\u30eb\u30ab\u30b9\u30b1\u30fc\u30c9\u306e\u52d5\u614b\u306b\u3088\u3063\u3066\u6c7a\u307e\u308b\u53d7\u5bb9\u4f53\u30c8\u30ea\u30ac\u30fc\u30da\u30d7\u30c1\u30c9\u306b\u5178\u578b\u7684\u3067\u3059\u3002<\/p>\n<h3>\u7d44\u7e54\u4fee\u5fa9\u7814\u7a76\u306b\u304a\u3044\u3066\u3001ARA-290\u306fBPC-157\u3068\u3069\u306e\u3088\u3046\u306b\u6bd4\u8f03\u3055\u308c\u307e\u3059\u304b\uff1f<\/h3>\n<p>\u4e21\u65b9\u306e\u30da\u30d7\u30c1\u30c9\u306f\u7d44\u7e54\u4fee\u5fa9\u7814\u7a76\u306b\u7528\u3044\u3089\u308c\u307e\u3059\u304c\u3001\u6a19\u7684\u3068\u3059\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u7d44\u7e54\u304c\u7570\u306a\u308a\u307e\u3059\u3002ARA-290\u306f\u81ea\u7136\u4fee\u5fa9\u53d7\u5bb9\u4f53\uff08EPOR + CD131\uff09\u3092\u4ecb\u3057\u3066\u4f5c\u7528\u3057\u3001\u672b\u68a2\u795e\u7d4c\u3001\u89d2\u819c\u3001\u865a\u8840\u7d44\u7e54\u306e\u7814\u7a76\u3067\u6700\u3082\u3088\u304f\u7279\u5fb4\u4ed8\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002 <a href=\"https:\/\/medsbase.com\/ja\/bpc-157\/\">BPC-157<\/a> 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