{"id":3567,"count":26,"description":"\u80c3\u9178\u9006\u6d41\u3001\u80f8\u3084\u3051\u3001\u6d88\u5316\u6027\u6f70\u760d\u3001\u3073\u3089\u3093\u6027\u98df\u9053\u708e\u306f\u3001\u4e16\u754c\u4e2d\u3067\u6700\u3082\u4e00\u822c\u7684\u306a\u6162\u6027\u75be\u60a3\u306e\u4e00\u90e8\u3067\u3042\u308a\u3001\u6b27\u7c73\u306e\u6210\u4eba\u306e10\uff5e30\uff05\u3001\u5357\u30a2\u30b8\u30a2\u3084\u6771\u30a2\u30b8\u30a2\u3067\u3082\u540c\u7a0b\u5ea6\u306e\u5272\u5408\u3067\u5f71\u97ff\u3092\u53ca\u307c\u3057\u3066\u3044\u307e\u3059\u3002\u73fe\u4ee3\u306e\u9178\u95a2\u9023\u75be\u60a3\u306f\u975e\u5e38\u306b\u6cbb\u7642\u53ef\u80fd\u3067\u3042\u308a\u3001\u5e83\u304f\u5165\u624b\u53ef\u80fd\u306a\u5185\u670d\u85ac\u306b\u3088\u308a\u80c3\u5185pH\u3092\u78ba\u5b9f\u304b\u3064\u5b89\u5168\u306b\u4e0a\u6607\u3055\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u3001\u6839\u672c\u539f\u56e0\uff08\u30d8\u30ea\u30b3\u30d0\u30af\u30bf\u30fc\u30fb\u30d4\u30ed\u30ea\u611f\u67d3\u3001NSAIDs\u306b\u3088\u308b\u640d\u50b7\u3001\u751f\u6d3b\u7fd2\u6163\u8981\u56e0\u3001\u98df\u9053\u88c2\u5b54\u30d8\u30eb\u30cb\u30a2\uff09\u306e\u8a3a\u65ad\u3068\u5bfe\u51e6\u3082\u53ef\u80fd\u3067\u3059\u3002MedsBase\u306e\u80c3\u9178\u9006\u6d41\u30ab\u30c6\u30b4\u30ea\u30fc\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u75be\u60a3\u306b\u4f7f\u7528\u3055\u308c\u308b3\u3064\u306e\u85ac\u5264\u30af\u30e9\u30b9\u3059\u3079\u3066\u306b\u52a0\u3048\u3001\u7c98\u819c\u4fdd\u8b77\u5264\u3068\u30c1\u30e5\u30a2\u30d6\u30eb\u5236\u9178\u5264\u3092\u53d6\u308a\u6271\u3063\u3066\u304a\u308a\u3001WHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\u304b\u3089\u306e26\u88fd\u54c1\u304c\u63c3\u3063\u3066\u3044\u307e\u3059\u3002\n\n<strong>\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u963b\u5bb3\u85ac\uff08PPI\uff09<\/strong> \u6700\u3082\u5f37\u529b\u306a\u80c3\u9178\u5206\u6ccc\u6291\u5236\u30af\u30e9\u30b9\u3067\u3042\u308a\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u80c3\u98df\u9053\u9006\u6d41\u75c7\uff08GERD\uff09\u3001\u3073\u3089\u3093\u6027\u98df\u9053\u708e\u3001\u6d88\u5316\u6027\u6f70\u760d\u306e\u6cbb\u7652\u3001NSAID\u6f70\u760d\u4e88\u9632\u3001\u30d8\u30ea\u30b3\u30d0\u30af\u30bf\u30fc\u30fb\u30d4\u30ed\u30ea\u9664\u83cc\u7642\u6cd5\u306b\u304a\u3051\u308b\u7b2c\u4e00\u9078\u629e\u6cbb\u7642\u3067\u3059\u3002\u80c3\u58c1\u7d30\u80de\u306eH+\/K+-ATPase\u30d7\u30ed\u30c8\u30f3\u30dd\u30f3\u30d7\u3092\u4e0d\u53ef\u9006\u7684\u306b\u906e\u65ad\u3059\u308b\u3053\u3068\u3067\u4f5c\u7528\u3057\u307e\u3059\u3002\u4ee5\u4e0b\u306e6\u7a2e\u985e\u306ePPI\u5206\u5b50\u3092\u53d6\u308a\u63c3\u3048\u3066\u3044\u307e\u3059\uff1a <strong>\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/strong> \uff08Omeeforce\u3001Omeford\u3001Omesec\u3001Omez\u3001Omez 20 \u2014 \u6700\u521d\u306ePPI\u3001\u4e16\u754c\u7684\u306aOTC\u6a19\u6e96\u85ac\uff09, <strong>\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb<\/strong> (Esoprol\u3001Neksium\u3001Nexpro \u2014 \u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb\u306eS\u7570\u6027\u4f53\u3067\u3001AUC\u304c30%\u9ad8\u304f\u3001\u91cd\u5ea6\u306e\u3073\u3089\u3093\u6027\u75be\u60a3\u306e\u6cbb\u7652\u304c\u3088\u308a\u901f\u3084\u304b\u3067\u3059\u3002), <strong>\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb<\/strong> \uff08Pan\u3001Pantodac\u3001Pentab\u3001Penlip\u3001Walapan-40 \u2014 \u30af\u30e9\u30b9\u5185\u3067\u6700\u3082\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u306e\u5c11\u306a\u3044\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3067\u3001\u30af\u30ed\u30d4\u30c9\u30b0\u30ec\u30eb\u670d\u7528\u8005\u3084\u8907\u96d1\u306a\u591a\u5264\u4f75\u7528\u306b\u597d\u307e\u308c\u307e\u3059\uff09\u3001, <strong>\u30e9\u30f3\u30bd\u30d7\u30e9\u30be\u30fc\u30eb<\/strong> \uff08Lan\u3001Lanzol\u3001Pepzol \u2014 \u521d\u65e5\u304b\u3089\u52b9\u679c\u767a\u73fe\u304c\u65e9\u3044\uff09\u3001, <strong>\u30e9\u30d9\u30d7\u30e9\u30be\u30fc\u30eb<\/strong> \uff08Rabium\u3001Razo \u2014 \u4e00\u90e8\u975e\u9175\u7d20\u7684\u306b\u6d3b\u6027\u5316\u3055\u308c\u3001CYP2C19\u4f9d\u5b58\u6027\u304c\u4f4e\u3044\uff09\u3001\u304a\u3088\u3073 <strong>\u30a4\u30e9\u30d7\u30e9\u30be\u30fc\u30eb<\/strong> \uff08Ilapro \u2014 \u534a\u6e1b\u671f\u304c\u7d049\u6642\u9593\u3068\u9577\u304f\u300124\u6642\u9593\u6301\u7d9a\u7684\u306a\u80c3\u9178\u6291\u5236\u3092\u5b9f\u73fe\uff09\u3002\n\n<strong>Pantocid Injection<\/strong> \u306f\u3001\u75c5\u9662\u7528\u9759\u6ce8\u88fd\u5264\u306e\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb40mg\uff0f\u30d0\u30a4\u30a2\u30eb\u3067\u3001\u4e0a\u90e8\u6d88\u5316\u7ba1\u51fa\u8840\uff08\u5185\u8996\u93e1\u7684\u6b62\u8840\u5f8c80mg\u30dc\u30fc\u30e9\u30b9\uff0b8mg\uff0f\u6642\u70b9\u6ef4\u00d772\u6642\u9593\uff09\u3001\u7d76\u98df\u60a3\u8005\u3001ICU\u30b9\u30c8\u30ec\u30b9\u6f70\u760d\u4e88\u9632\u306b\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002 <strong>Pantocid DSR<\/strong> \u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb40mg\u3068\u30c9\u30f3\u30da\u30ea\u30c9\u30f330mg\u5f90\u653e\u6027\u30921\u30ab\u30d7\u30bb\u30eb\u306b\u914d\u5408\u3057\u3001\u904b\u52d5\u6a5f\u80fd\u969c\u5bb3\u304c\u4e3b\u306a\u554f\u984c\uff08\u9006\u6d41\u3092\u4f34\u3046GERD\u3001\u80c3\u4e0d\u5168\u9ebb\u75fa\u3001\u98df\u5f8c\u81a8\u6e80\u611f\uff09\u306b\u6709\u7528\u3067\u3059\u304c\u3001\u30c9\u30f3\u30da\u30ea\u30c9\u30f3\u306eQT\u9593\u9694\u5ef6\u9577\u30ea\u30b9\u30af\u306e\u305f\u3081\u3001\u5fc3\u81d3\u5b89\u5168\u6027\u3078\u306e\u914d\u616e\u304c\u5fc5\u9808\u3067\u3059\u3002\n\n<strong>\u30d2\u30b9\u30bf\u30df\u30f3H2\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac<\/strong> \u306f\u3001\u58c1\u7d30\u80de\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u7d4c\u8def\u306e\u7570\u306a\u308b\u30dd\u30a4\u30f3\u30c8\u3067\u80c3\u9178\u5206\u6ccc\u3092\u6291\u5236\u3057\u307e\u3059\u3002PPI\u3088\u308a\u3082\u901f\u304f\u4f5c\u7528\u3057\uff0830\u5206\u4ee5\u5185\uff09\u3001\u6700\u5927\u6291\u5236\u52b9\u679c\u306f\u6d45\u304f\u3001\u9023\u75287\uff5e14\u65e5\u3067\u30bf\u30ad\u30d5\u30a3\u30e9\u30ad\u30b7\u30fc\u304c\u751f\u3058\u307e\u3059\u3002 <strong>Famocid<\/strong> \uff08Sun Pharma\u793e\u306e\u30d5\u30a1\u30e2\u30c1\u30b8\u30f320\uff0f40mg\uff09\u306f\u3001\u73fe\u4ee3\u3067\u597d\u307e\u308c\u308bH2\u62ee\u6297\u85ac\u3067\u3001\u5fc5\u8981\u6642\u306e\u670d\u7528\u306b\u3088\u308b\u8efd\u5ea6GERD\u3001PPI\u4f7f\u7528\u4e2d\u306e\u7a81\u51fa\u75c7\u72b6\uff08\u7279\u306b\u591c\u9593\uff09\u3001NSAID\u6f70\u760d\u4e88\u9632\u3001\u598a\u5a20\u4e2d\u306e\u9006\u6d41\u306b\u6709\u7528\u3067\u3059\u3002 <strong>\u30d5\u30a1\u30e2\u30c1\u30b8\u30f3\u306f\u30e9\u30cb\u30c1\u30b8\u30f3\u306e\u63a8\u5968\u4ee3\u66ff\u85ac\u3067\u3059\u3002<\/strong>, \u30012020\u5e74\u306bN-\u30cb\u30c8\u30ed\u30bd\u30b8\u30e1\u30c1\u30eb\u30a2\u30df\u30f3\uff08NDMA\uff09\u306e\u767a\u304c\u3093\u6027\u7269\u8cea\u6c5a\u67d3\u306e\u305f\u3081\u3001\u7c73\u56fd\u3001EU\u3001\u82f1\u56fd\u3001\u30ab\u30ca\u30c0\u5e02\u5834\u304b\u3089\u64a4\u9000\u3057\u307e\u3057\u305f\u3002 <strong>Aciloc<\/strong> \uff08Cadila\u793e\u306e\u30e9\u30cb\u30c1\u30b8\u30f3150\/300 mg\uff09\u304a\u3088\u3073 <strong>Rantac 300<\/strong> \uff08\u30e9\u30cb\u30c1\u30b8\u30f3300 mg\uff09\u306f\u30a4\u30f3\u30c9\u5e02\u5834\u3067\u306f\u5f15\u304d\u7d9a\u304d\u5165\u624b\u53ef\u80fd\u3067\u3059\u3002\u30a4\u30f3\u30c9\u306e\u898f\u5236\u5f53\u5c40CDSCO\u306f\u6b63\u5f0f\u306a\u64a4\u9000\u3092\u884c\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u5404\u88fd\u54c1\u30da\u30fc\u30b8\u306b\u306fNDMA\u306b\u95a2\u3059\u308b\u660e\u78ba\u306a\u8b66\u544a\u304c\u8a18\u8f09\u3055\u308c\u3001\u30d5\u30a1\u30e2\u30c1\u30b8\u30f3\u3078\u306e\u5207\u308a\u66ff\u3048\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u307e\u3059\u3002\n\n<strong>\u7c98\u819c\u4fdd\u8b77\u5264\u3068\u5236\u9178\u5264<\/strong> \u5c40\u6240\u7684\u306b\u4f5c\u7528\u3057\u3001\u9178\u5206\u6ccc\u6291\u5236\u3092\u88dc\u5b8c\u3059\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u305d\u308c\u306b\u53d6\u3063\u3066\u4ee3\u308f\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002 <strong>Macralfate\uff08\u30de\u30af\u30e9\u30eb\u30d5\u30a7\u30fc\u30c8\uff09\u61f8\u6fc1\u6db2<\/strong> \u30b9\u30af\u30e9\u30eb\u30d5\u30a1\u30fc\u30c81 g\/10 mL\u3067\u3059\u3002\u3053\u308c\u306f\u30a2\u30eb\u30df\u30cb\u30a6\u30e0-\u30b9\u30af\u30ed\u30fc\u30b9-\u30aa\u30af\u30bf\u786b\u9178\u8907\u5408\u4f53\u3067\u3001\u80c3\u9178\u4e2d\u3067\u91cd\u5408\u3057\u3001\u6f70\u760d\u3092\u7269\u7406\u7684\u306b\u88ab\u8986\u3057\u3066\u6cbb\u7652\u3092\u4fc3\u9032\u3057\u307e\u3059\u3002\u6d88\u5316\u6027\u6f70\u760d\u3001\u80c6\u6c41\u9006\u6d41\u6027\u80c3\u708e\uff08PPI\u306e\u52b9\u679c\u304c\u4f4e\u3044\u5834\u5408\uff09\u3001NSAID\u80c3\u708e\u3001\u653e\u5c04\u7dda\u98df\u9053\u708e\u3001\u5316\u5b66\u7642\u6cd5\u306b\u3088\u308b\u53e3\u8154\u7c98\u819c\u708e\u306b\u6709\u7528\u3067\u3059\u3002 <strong>Acigene<\/strong> \u306f\u3001\u6c34\u9178\u5316\u30a2\u30eb\u30df\u30cb\u30a6\u30e0\uff0b\u6c34\u9178\u5316\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\uff0b\u30b7\u30e1\u30c1\u30b3\u30f3\uff0b\u30b1\u30a4\u9178\u30a2\u30eb\u30df\u30cb\u30a6\u30e0\u30de\u30b0\u30cd\u30b7\u30a6\u30e0\u3092\u914d\u5408\u3057\u305f\u30c1\u30e5\u30a2\u30d6\u30eb\u5236\u9178\u5264\u3067\u3059\u3002\u7a81\u51fa\u75c7\u72b6\u3084PPI\u304c\u5341\u5206\u306a\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u307e\u3067\u306e\u6a4b\u6e21\u3057\u7642\u6cd5\u3068\u3057\u3066\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u5236\u9178\u5264\u306f\u6570\u5206\u3067\u52b9\u679c\u304c\u73fe\u308c\u307e\u3059\u304c\u3001\u6301\u7d9a\u6642\u9593\u306f30\uff5e60\u5206\u3067\u3059\u3002\n\n<strong>\u9078\u3073\u65b9\uff1a<\/strong> \u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u6162\u6027\u9006\u6d41\u3001\u6d88\u5316\u6027\u6f70\u760d\u3001\u3073\u3089\u3093\u6027\u98df\u9053\u708e\u3001\u307e\u305f\u306f\u30d4\u30ed\u30ea\u83cc\u9664\u83cc\u306b\u306f\u3001PPI\u304c\u7b2c\u4e00\u9078\u629e\u3067\u3059\u3002\u85ac\u7269\u76f8\u4e92\u4f5c\u7528\u304c\u61f8\u5ff5\u3055\u308c\u308b\u5834\u5408\u306f\u30d1\u30f3\u30c8\u30d7\u30e9\u30be\u30fc\u30eb\uff08Pan\u3001Pantodac\u3001Walapan-40\uff09\u3001\u91cd\u5ea6\u306e\u3073\u3089\u3093\u6027\u75be\u60a3\u306b\u306f\u30a8\u30bd\u30e1\u30d7\u30e9\u30be\u30fc\u30eb\uff08Esoprol\u3001Neksium\u3001Nexpro\uff09\u3001\u30b3\u30b9\u30c8\u30d1\u30d5\u30a9\u30fc\u30de\u30f3\u30b9\u306b\u512a\u308c\u305f\u4e3b\u529b\u85ac\u3068\u3057\u3066\u30aa\u30e1\u30d7\u30e9\u30be\u30fc\u30eb\uff08Omez\u3001Omesec\uff09\u3001\u6a19\u6e96\u7684\u306aPPI\u3067\u591c\u9593\u9178\u7a81\u7834\u304c\u898b\u3089\u308c\u308b\u5834\u5408\u306b\u306f\u30a4\u30e9\u30d7\u30e9\u30be\u30fc\u30eb\uff08Ilapro\uff09\u3001CYP2C19\u4f4e\u4ee3\u8b1d\u578b\u306b\u306f\u30e9\u30d9\u30d7\u30e9\u30be\u30fc\u30eb\uff08Razo\u3001Rabium\uff09\u3092\u9078\u629e\u3057\u307e\u3059\u3002\u8efd\u5ea6\u306e\u5fc5\u8981\u6642\u9006\u6d41\u3084PPI\u670d\u7528\u4e2d\u306e\u7a81\u51fa\u75c7\u72b6\u306b\u306f\u3001H2\u62ee\u6297\u85ac\u3068\u3057\u3066\u30d5\u30a1\u30e2\u30c1\u30b8\u30f3\uff08Famocid\uff09\u304c\u9078\u629e\u3055\u308c\u307e\u3059\u3002\u7c98\u819c\u88ab\u8986\u304c\u6709\u52b9\u306a\u6d88\u5316\u6027\u6f70\u760d\u306e\u6cbb\u7652\u3084\u80c6\u6c41\u9006\u6d41\u6027\u80c3\u708e\u306b\u306f\u3001\u30b9\u30af\u30e9\u30eb\u30d5\u30a1\u30fc\u30c8\uff08Macralfate\uff09\u3092\u8ffd\u52a0\u3057\u307e\u3059\u3002\u98df\u5f8c\u306e\u4e0d\u5b9a\u671f\u306a\u80f8\u3084\u3051\u3084PPI\u306e\u52b9\u679c\u767a\u73fe\u307e\u3067\u306e\u6a4b\u6e21\u3057\u306b\u306f\u3001\u5236\u9178\u5264\uff08Acigene\uff09\u304c\u6700\u3082\u8fc5\u901f\u306a\u7de9\u548c\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002 <strong>\u30a2\u30e9\u30fc\u30e0\u75c7\u72b6<\/strong> \u2014 \u539f\u56e0\u4e0d\u660e\u306e\u4f53\u91cd\u6e1b\u5c11\u3001\u56a5\u4e0b\u56f0\u96e3\u3001\u5410\u8840\u3001\u9ed2\u8272\u4fbf\u3001\u8ca7\u8840\u300155\u6b73\u4ee5\u4e0a\u306e\u65b0\u898f\u767a\u75c7\u306e\u9006\u6d41\u75c7\u72b6 \u2014 \u3053\u308c\u3089\u306e\u75c7\u72b6\u306b\u306f\u7d4c\u9a13\u7684\u306a\u80c3\u9178\u6291\u5236\u7642\u6cd5\u3067\u306f\u306a\u304f\u3001\u7cbe\u67fb\u304c\u5fc5\u8981\u3067\u3059\u3002\\n\\n\u516826\u88fd\u54c1\u306fWHO-GMP\u8a8d\u8a3c\u306e\u88fd\u9020\u5143\uff08Sun Pharma\u3001Cipla\u3001Dr. Reddy\u2019s\u3001AstraZeneca India\u3001Torrent\u3001Zydus Cadila\u3001Alkem\u3001Intas\u3001JB Chemicals\u306a\u3069\uff09\u3088\u308a\u767a\u9001\u3055\u308c\u307e\u3059\u3002\u3059\u3079\u3066\u306e\u3054\u6ce8\u6587\u306b\u306f\u3001\u5f53\u5e97\u306e <strong>\u518d\u767a\u9001\u4fdd\u8a3c\u30dd\u30ea\u30b7\u30fc<\/strong> \u2014 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