<\/p>\n
App-Up<\/strong> er et merkevarenavn for cyproheptadine hydrochloride<\/strong> (4 mg), a first-generation (sedating) oral antihistamine<\/strong> of the piperidine class (also a serotonin 5-HT2<\/sub> antagonist). Used for allergic rhinitis, urticaria (hives), itchy skin, insect-bite reactions, and mild allergic reactions<\/strong>. Onset: 30–60 minutes; duration: 4–6 hours — so doses are typically spread 2–3 times daily. A dual H1 + 5-HT2<\/sub> antagonist<\/strong>. Strongest anti-itch effect of the 1st-gen antihistamines, but with prominent sedation, appetite stimulation, and weight gain. Widely used in India, Latin America, and Asia — less common in Western countries, where 2nd-generation antihistamines dominate. Causes drowsiness<\/strong> in most users — do not drive or operate machinery after a dose until you know how it affects you. Avoid in narrow-angle glaucoma, bladder-outflow obstruction, severe asthma attack, and in older adults where alternatives exist. Not a treatment for anaphylaxis — severe allergic reactions need adrenaline.<\/p>\n<\/div>\n \ud83d\udce6 Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis pakken din ikke ankommer innen 20 virkedager, sender vi ny.<\/p>\n V\u00e5re generiske legemidler kommer fra WHO-GMP-sertifiserte produsenter og sendes over hele verden i diskret, n\u00f8ytral emballasje \u2014 ingen legemiddelnavn p\u00e5 utsiden av pakken. Kortbetalinger h\u00e5ndteres av en regulert betalingsbehandler (kontoutskrifter viser en regulert kortbetalingsprosessor \u2014 aldri \u201cMedsBase\u201d eller noe legemiddelnavn). Krypto og SEPA bankoverf\u00f8rsel godtas ogs\u00e5. Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy.<\/p>\n App-Up is an oral antihistamine containing cyproheptadine hydrochloride<\/strong> (4 mg), manufactured by WHO-GMP certified manufacturer. Supplied in packs of 30, 60, 90 or 180 tablets. Originator brand: Periactin (Merck, 1961).<\/p>\n cyproheptadine hydrochloride belongs to the first-generation H1 antihistamine class<\/strong> — the original antihistamines developed in the 1940s and 50s. They are effective but, unlike newer agents, cross the blood-brain barrier readily, which causes sedation and anticholinergic side effects. First-generation antihistamines are still useful for acute allergic episodes, short-term night-time itch, and specialised uses (motion sickness, certain migraine protocols, appetite stimulation).<\/p>\n Allergic rhinitis, urticaria, itchy skin, serotoninsyndrom<\/strong> (antidote use), cyproheptadine is also widely used off-label as an appetite stimulant<\/strong> in poor-appetite states and failure-to-thrive. Historically used in migraine prevention, carcinoid syndrome (for diarrhoea\/flushing), and SSRI-induced sexual dysfunction.<\/p>\n cyproheptadine hydrochloride blocks histamine H1 receptors<\/strong> throughout the body. Histamine is released from mast cells and basophils during allergic reactions and causes the classic symptoms: sneezing, runny nose, itchy eyes, vasodilation, urticaria, bronchoconstriction, and mucus secretion. Blocking H1 receptors interrupts these effects.<\/p>\n Unlike newer (2nd-generation) antihistamines, first-generation agents readily cross the blood-brain barrier and bind central H1 receptors — producing sedation. They also have appreciable affinity for muscarinic acetylcholine receptors<\/strong>, causing classic anticholinergic effects (dry mouth, urinary hesitancy, blurred vision, constipation). Cyproheptadine additionally blocks serotonin 5-HT2<\/sub> reseptorer<\/strong>, giving it unique uses in serotonin syndrome, carcinoid syndrome, and appetite stimulation.<\/p>\n Dose:<\/strong> Adults: 4 mg 3 times daily (usual range 4–20 mg\/day; max 32 mg\/day). Children 7–14: 4 mg 2–3 times daily. Children 2–6: 2 mg 2–3 times daily.<\/p>\n Sedation:<\/strong> Cyproheptadine is markant sedativ<\/strong> and commonly causes drowsiness. Most patients experience sedation at standard doses; tolerance may develop partially over 1–2 weeks.<\/p>\n Anticholinergic:<\/strong> Moderate — dry mouth, blurred vision, urinary hesitancy, constipation. Avoid in narrow-angle glaucoma, bladder-outflow obstruction, and elderly with falls risk.<\/p>\n Vekt:<\/strong> Significant appetite stimulation and weight gain<\/strong> are characteristic effects — cyproheptadine is routinely prescribed off-label as a weight-gain aid in children with anorexia or failure to thrive. Can be a desired or undesired effect depending on context.<\/p>\n Other common side effects:<\/strong><\/p>\n Sjeldne, men viktige:<\/strong><\/p>\n Graviditet:<\/strong> first-generation antihistamines have been used for decades with a reasonable safety record, but 2nd-generation agents (loratadine, cetirizine) are preferred first-line. Discuss with your obstetrician before starting.<\/p>\n Amming:<\/strong> 1st-generation antihistamines pass into breast milk and may sedate the infant. They can also reduce milk supply. Prefer loratadine or cetirizine when treatment is needed in a breastfeeding mother.<\/p>\n Barn:<\/strong> age cutoffs in the Dosage section. Paradoxical excitation can occur in young children.<\/p>\n Store App-Up below 25°C in a dry place, in the original blister. Keep out of reach of children.<\/p>\n Yes — App-Up contains the active ingredient cyproheptadine hydrochloride. Bioequivalence to the originator brand (Periactin (Merck, 1961)) is required by regulatory authorities.<\/p>\n Yes — cyproheptadine is one of the most commonly prescribed off-label appetite stimulants in children with failure-to-thrive, poor appetite, or cachexia, and sometimes in adults. Typical dose is 2–4 mg 2–3 times daily; weight gain of 1–3 kg over 4–8 weeks is typical. It is not approved as a weight-gain agent<\/strong> in most countries, and the effect is driven by H1 blockade and serotonin antagonism in the hypothalamic appetite centre. Discuss with a doctor before using for this purpose.<\/p>\n Cyproheptadine is markant sedativ<\/strong> and commonly causes drowsiness. Most patients experience sedation at standard doses; tolerance may develop partially over 1–2 weeks. Plan your first dose for a time when you do not need to drive or operate machinery for at least 6–8 hours. Effect is dose-dependent; smaller split doses often cause less sedation than a single large dose.<\/p>\n First-generation antihistamines are generally not recommended for long-term daily use when 2nd-generation agents are available — the anticholinergic burden and sedation add up. For chronic hay fever or urticaria, switch to loratadine, cetirizine, or fexofenadine. Short courses are safe for acute episodes.<\/p>\n No. Alcohol and first-generation antihistamines both depress the central nervous system; combining them significantly increases drowsiness, impaired coordination, and risk of accidents.<\/p>\n Age cutoffs differ by formulation — see the dosage section. Paradoxical excitation (irritability, hyperactivity, trouble sleeping) is a recognised reaction in young children; if it occurs, stop and consult a doctor. For routine allergies in children, cetirizine or loratadine are preferred first-line.<\/p>\n You can order App-Up (4 mg) from MedsBase in packs of 30, 60, 90 or 180 tablets. We ship worldwide with discreet packaging and genuine WHO-GMP certified manufacturer stock.<\/p>\n <\/p>\n Andre produkter innen Kroniske tilstander<\/strong> som kunder ogs\u00e5 ser p\u00e5:<\/p>\n \u2705 Boosts appetite App-Up contains Cyproheptadine.<\/p>","protected":false},"featured_media":56525,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3975],"product_tag":[4109,4110],"class_list":{"0":"post-56524","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-hay-fever-allergies-treatment","9":"product_tag-app-up","10":"product_tag-cyproheptadine","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product\/56524","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/comments?post=56524"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media\/56525"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media?parent=56524"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_brand?post=56524"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_cat?post=56524"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_tag?post=56524"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Hvorfor bestille fra MedsBase<\/h3>\n
What Is App-Up?<\/h2>\n
What Is App-Up Used For?<\/h2>\n
How Does App-Up Work?<\/h2>\n
Dosering og administrering<\/h2>\n
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Bivirkninger<\/h2>\n
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Legemiddelinteraksjoner<\/h2>\n
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Who Should Not Take App-Up?<\/h2>\n
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Use in Pregnancy and Children<\/h2>\n
Oppbevaring<\/h2>\n
Vanlige sp\u00f8rsm\u00e5l<\/h2>\n
Is App-Up the same as cyproheptadine hydrochloride?<\/h3>\n
Is cyproheptadine used for weight gain?<\/h3>\n
How drowsy will App-Up make me?<\/h3>\n
Can I take App-Up every day?<\/h3>\n
Can I drink alcohol with App-Up?<\/h3>\n
Can I give App-Up to my child?<\/h3>\n
Where can I buy App-Up online?<\/h3>\n
Relaterte allergimedisiner<\/h2>\n
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Relaterte alternativer<\/h3>\n
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\n\u2705 Enhances weight gain
\n\u2705 Manages allergies
\n\u2705 Relieves itching
\n\u2705 Treats migraine<\/p>\n