{"id":58482,"date":"2024-02-27T18:38:32","date_gmt":"2024-02-27T18:38:32","guid":{"rendered":"https:\/\/medsname.com\/lukotas\/"},"modified":"2026-04-30T10:24:12","modified_gmt":"2026-04-30T10:24:12","slug":"lukotas","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nb\/product\/lukotas\/","title":{"rendered":"Lukotas"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Lukotas?<\/h3>\n<p><strong>Lukotas<\/strong> inneholder <strong>montelukast<\/strong>, an oral preventer for asthma and allergic rhinitis. Montelukast blocks <strong>cysteinyl leukotriene receptors (CysLT1)<\/strong>, mediators released by mast cells and eosinophils that drive bronchoconstriction, mucus production, and airway oedema. Used as add-on preventer therapy for asthma, especially exercise-induced and allergy-triggered asthma, and for allergic rhinitis. Each tablet contains <strong>4 \/ 5 \/ 10 mg<\/strong>, produsert av <strong>Intas Pharmaceuticals<\/strong>. Taken <strong>once daily in the evening<\/strong>.<\/p>\n<p><strong>Important \u2014 neuropsychiatric warning:<\/strong> the FDA added a black-box warning in 2020 noting reports of mood changes, sleep disturbance, anxiety, depression, and (rarely) suicidal ideation with montelukast. Discuss any new mood symptoms with your prescriber.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Hva du f\u00e5r med MedsBase:<\/strong> WHO-GMP-sertifisert produsent \u00b7 Diskret emballasje \u00b7 Verdensomspennende levering \u00b7 1 400+ verifiserte <a href=\"https:\/\/medsbase.com\/nb\/reviews\/\">kundeanmeldelser<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis pakken din ikke ankommer innen 20 virkedager, sender vi ny.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>V\u00e5re generiske legemidler kommer fra WHO-GMP-sertifiserte produsenter og sendes over hele verden i diskret, n\u00f8ytral emballasje \u2014 ingen legemiddelnavn p\u00e5 utsiden av pakken. Kortbetalinger h\u00e5ndteres av en regulert betalingsbehandler (kontoutskrifter viser en regulert kortbetalingsprosessor \u2014 aldri \u201cMedsBase\u201d eller noe legemiddelnavn). Krypto og SEPA bankoverf\u00f8rsel godtas ogs\u00e5. Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Kryptert kasse<\/strong> \u00b7 <strong>\ud83d\udcb3 Verifisert betalingsbehandler<\/strong> \u00b7 <strong>\ud83d\ude9a Verdensomspennende frakt<\/strong> \u00b7 <strong>\u2b50 4,9\/5 fra 1 400+ kunder<\/strong>\n<\/div>\n<h2>What Is Lukotas?<\/h2>\n<p>Lukotas is a montelukast (LTRA) preparation manufactured by Intas Pharmaceuticals at WHO-GMP certified facilities. Internationally montelukast is sold as Singulair (MSD). Available as 4 mg, 5 mg, and 10 mg tablets \u2014 strengths chosen by age and indication.<\/p>\n<h2>How Does Lukotas Work?<\/h2>\n<p>Cysteinyl leukotrienes (LTC4, LTD4, LTE4) are inflammatory lipid mediators released by mast cells, eosinophils, and basophils when activated by allergen, exercise, cold air, or aspirin. They bind CysLT1 receptors on airway smooth muscle, eosinophils, and bronchial epithelium \u2014 driving bronchoconstriction, eosinophil recruitment, airway oedema, and mucus hypersecretion. Montelukast selectively blocks CysLT1, breaking this cascade.<\/p>\n<h2>Bruk og indikasjoner<\/h2>\n<ul>\n<li><strong>Persisterende astma<\/strong> \u2014 add-on preventer in patients not controlled by ICS alone (alternative to LABA or LAMA add-on)<\/li>\n<li><strong>Belastningsutl\u00f8st astma<\/strong> \u2014 particularly effective; taken 2 hours before exercise<\/li>\n<li><strong>Aspirin-exacerbated respiratory disease (AERD)<\/strong> \u2014 leukotrienes are central to this phenotype<\/li>\n<li><strong>Allergisk rhinit<\/strong> \u2014 both seasonal (hay fever) and perennial<\/li>\n<li><strong>Allergic conjunctivitis adjunct<\/strong><\/li>\n<li><strong>Kronisk urtikaria<\/strong> \u2014 montelukast as adjunct to high-dose antihistamine<\/li>\n<\/ul>\n<h2>Lukotas Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Pasient<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dose<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Frekvens<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Adults &amp; children &gt;15 yr<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>10 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">En gang daglig om kvelden<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Barn 6\u201314 \u00e5r<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>5 mg chewable<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">En gang daglig om kvelden<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Barn 2\u20135 \u00e5r<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>4 mg chewable \/ granules<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">En gang daglig om kvelden<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Children 6 mo \u2013 2 yr<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>4 mg granules<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">En gang daglig \u2014 spesialistoverv\u00e5kning<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Side Effects of Lukotas<\/h2>\n<ul>\n<li>Hodepine<\/li>\n<li>Mild magesmerte eller kvalme<\/li>\n<li>Sleep disturbance (vivid dreams, insomnia)<\/li>\n<li>Mood changes \u2014 irritability, anxiety, depression (FDA black-box warning, 2020)<\/li>\n<li>Upper respiratory infection symptoms<\/li>\n<li>Utslett<\/li>\n<\/ul>\n<p><strong>Alvorlig \u2014 stopp og s\u00f8k hjelp:<\/strong><\/p>\n<ul>\n<li>Alvorlig allergisk reaksjon \/ angio\u00f8dem<\/li>\n<li>Suicidal ideation or severe depression \u2014 STOP and seek urgent psychiatric review<\/li>\n<li>Churg-Strauss syndrome (eosinophilic vasculitis) \u2014 rare; suspect in ICS-tapering patients with new vasculitic features (rash, neuropathy, eosinophilia)<\/li>\n<li>Hepatitis (rare)<\/li>\n<\/ul>\n<h2>Advarsler og forholdsregler<\/h2>\n<ul>\n<li><strong>Black-box warning \u2014 neuropsychiatric events.<\/strong> If new mood changes, anxiety, sleep disturbance, agitation, depression, or suicidal thoughts occur, stop Lukotas and contact your prescriber.<\/li>\n<li><strong>Ikke et akuttmedikament.<\/strong> Do not use in acute asthma attacks \u2014 onset is too slow.<\/li>\n<li><strong>Fortsett med ICS<\/strong> if previously prescribed; montelukast does not replace inhaled corticosteroids.<\/li>\n<li><strong>Leverfunksjonssvikt:<\/strong> use cautiously in moderate-to-severe disease.<\/li>\n<li><strong>Graviditet og amming:<\/strong> reasonable safety data; use when benefits outweigh risks.<\/li>\n<li><strong>Barn<\/strong> may show increased risk of behavioural changes \u2014 counsel parents to monitor mood.<\/li>\n<\/ul>\n<h2>Kontraindikasjoner<\/h2>\n<ul>\n<li>Hypersensitivity to montelukast or excipients<\/li>\n<li>Severe hepatic impairment \u2014 relative<\/li>\n<li><\/li>\n<\/ul>\n<h2>Legemiddelinteraksjoner<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Interagerende legemiddel<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Effekt<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Hva du b\u00f8r gj\u00f8re<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Phenobarbital, phenytoin, rifampicin<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Induce CYP enzymes \u2014 reduce montelukast levels<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor asthma control<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Gemfibrozil<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Inhibits CYP2C8 \u2014 increases montelukast levels<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Bruk med forsiktighet<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Warfarin<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Theoretical INR change reported in case reports<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Monitor INR after starting\/stopping<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Oppbevaring<\/h2>\n<ul>\n<li>Oppbevar under <strong>25\u00b0C<\/strong> p\u00e5 et kj\u00f8lig, t\u00f8rt sted unna direkte sollys.<\/li>\n<li>Oppbevar i originalemballasje til bruk for \u00e5 beskytte mot fuktighet og lys.<\/li>\n<li>Ikke bruk etter utl\u00f8psdatoen som st\u00e5r p\u00e5 strimlen.<\/li>\n<li>Oppbevar utilgjengelig for barn.<\/li>\n<\/ul>\n<h2>Relaterte alternativer p\u00e5 MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/asthalin-inhaler\/\"><strong>Asthalin Inhaler \u2014 salbutamol lindringsmiddel<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/budecort-inhaler\/\"><strong>Budecort Inhaler \u2014 budesonide ICS forebyggende<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/foracort-inhaler\/\"><strong>Foracort Inhaler \u2014 budesonide + formoterol ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/tiova-inhaler\/\"><strong>Tiova Inhaler \u2014 tiotropium LAMA for KOLS<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/montair\/\"><strong>Montair \u2014 montelukast LTRA tablett<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Vanlige sp\u00f8rsm\u00e5l<\/h2>\n<h3>When should I take montelukast?<\/h3>\n<p>Once daily in the evening, with or without food. Evening dosing matches the typical overnight rise in leukotriene mediators and gives best protection against early-morning symptoms.<\/p>\n<h3>How long until montelukast works?<\/h3>\n<p>Some symptom relief within 24\u201348 hours. Full effect on asthma exacerbation rate develops over 4\u20138 weeks.<\/p>\n<h3>Should I worry about the FDA black-box warning?<\/h3>\n<p>The 2020 FDA black-box warning highlighted reports of mood changes, sleep disturbance, anxiety, depression, and rarely suicidal ideation \u2014 particularly in children. The absolute risk is low but real. Watch for any new mood symptoms in yourself or your child; stop the drug and contact your prescriber if they appear.<\/p>\n<h3>Can montelukast replace my inhaler?<\/h3>\n<p>No \u2014 montelukast is an add-on preventer. It does not replace inhaled corticosteroids (Budecort, Beclate, Foracort, Seretide). Continue ICS as prescribed.<\/p>\n<h3>Is montelukast a rescue medication?<\/h3>\n<p>No \u2014 onset is too slow. Use a SABA (Asthalin, Levolin) for acute attacks.<\/p>\n<h3>Can children take montelukast?<\/h3>\n<p>Yes from 6 months of age in age-appropriate strengths (4 mg granules, 4 mg or 5 mg chewable, 10 mg tablet). Counsel parents to monitor mood and behaviour.<\/p>\n<h3>Is montelukast safe in pregnancy?<\/h3>\n<p>Reasonable observational data; use when benefits outweigh risks, particularly in patients whose asthma is well-controlled on it.<\/p>\n<h3>Does montelukast help allergic rhinitis?<\/h3>\n<p>Yes \u2014 montelukast is licensed for both asthma and allergic rhinitis. Particularly useful when both coexist (United Airways disease).<\/p>\n<h3>Should I stop montelukast if I feel better?<\/h3>\n<p>No \u2014 continue daily for as long as your prescriber advises. Stopping leads to gradual return of symptoms over days-to-weeks.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medisinsk ansvarsfraskrivelse:<\/strong> Denne siden er opplysningsmessig og erstatter ikke profesjonell medisinsk r\u00e5dgivning. Alltid konsulter en kvalifisert helsepersonell f\u00f8r du starter, stopper eller endrer enhver inhalator eller respirasjonsmedisin, spesielt hvis du har andre medisinske tilstander, tar andre reseptbelagte legemidler, er gravid eller ammer, eller er over 65 \u00e5r.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Relaterte alternativer<\/h3>\n<p>Andre produkter innen <strong>Kroniske tilstander<\/strong> som kunder ogs\u00e5 ser p\u00e5:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/calpol\/\">Calpol<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/hivus-lr\/\">Hivus LR<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/rami-race\/\">Rami Race<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/dynapar\/\">Dynapar<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/indicid-75-sr\/\">Indicid-75 SR<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 H\u00e5ndterer allergier<br \/>\n\u2705 Lindrer astmasymptomer<br \/>\n\u2705 Reduces bronchoconstriction<br \/>\n\u2705 Controls wheezing<br \/>\n\u2705 Prevents airway inflammation<\/p>\n<p>Lukotas contains Montelukast.<\/p>","protected":false},"featured_media":58483,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[4501,4499],"class_list":{"0":"post-58482","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-lukotas","10":"product_tag-montelukast","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product\/58482","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/comments?post=58482"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media\/58483"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media?parent=58482"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_brand?post=58482"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_cat?post=58482"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_tag?post=58482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}