{"id":58688,"date":"2024-02-28T05:23:07","date_gmt":"2024-02-28T05:23:07","guid":{"rendered":"https:\/\/medsname.com\/lupimeb\/"},"modified":"2026-05-07T07:15:50","modified_gmt":"2026-05-07T07:15:50","slug":"lupimeb","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nb\/product\/lupimeb\/","title":{"rendered":"Lupimeb"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div class=\"medsbase-tldr-answer\" style=\"margin:0 0 22px;padding:16px 20px;background:#fff8e1;border-left:4px solid #f5a623;border-radius:4px;\">\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px;font-size:18px;color:#2c3e50;\">Quick Answer &mdash; What is Lupimeb?<\/h3>\n<div style=\"margin:0;font-size:15px;line-height:1.55;color:#333;\">\n<p><strong>Lupimeb<\/strong> er en oral <strong>mebendazole 100&nbsp;mg chewable tablet<\/strong> fra <strong>Lupin<\/strong>. Mebendazole is a WHO Essential Medicine for <strong>pinworm, roundworm, hookworm, and whipworm<\/strong>. Standard voksendose: <strong>100&nbsp;mg as a single dose for pinworm, repeat in 2 weeks<\/strong>. For mixed infection or whipworm: <strong>100&nbsp;mg twice daily for 3 days<\/strong>.<\/p>\n<\/div>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"margin:24px 0;padding:14px 18px;background:#f4f4f4;border:1px solid #e1e1e1;border-radius:4px;font-size:14px;color:#444;line-height:1.55;\"><strong>Hvorfor bestille fra MedsBase:<\/strong> \u2713 Sourced from <strong>WHO-GMP-sertifiserte produsenter<\/strong> \u00b7 \u2713 Diskret emballasje \u00b7 \u2713 Verdensomspennende frakt \u00b7 \u2713 <strong>1,400+ kundeanmeldelser<\/strong> p\u00e5 <a href=\"https:\/\/medsbase.com\/nb\/reviews\/\">medsbase.com\/reviews<\/a><\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis pakken din ikke ankommer innen 20 virkedager, sender vi ny.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>V\u00e5re generiske legemidler kommer fra WHO-GMP-sertifiserte produsenter og sendes over hele verden i diskret, n\u00f8ytral emballasje \u2014 ingen legemiddelnavn p\u00e5 utsiden av pakken. Kortbetalinger h\u00e5ndteres av en regulert betalingsbehandler (kontoutskrifter viser en regulert kortbetalingsprosessor \u2014 aldri \u201cMedsBase\u201d eller noe legemiddelnavn). Krypto og SEPA bankoverf\u00f8rsel godtas ogs\u00e5. Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What is Lupimeb?<\/h2>\n<p><strong>Lupimeb<\/strong> is mebendazole 100&nbsp;mg chewable from <strong>Lupin<\/strong>. Mebendazole was the first benzimidazole anthelmintic in routine human use and remains a WHO Essential Medicine. Albendazole has overtaken it as first-line in most settings, but mebendazole has a niche role: it is preferred in patients with concurrent moderate-to-severe hepatic impairment (less hepatic metabolism) and is the agent of choice in some paediatric whipworm protocols.<\/p>\n<h2 class=\"wp-block-heading\">Mekanisme for virkning<\/h2>\n<p>Mebendazole binds <strong>\u03b2-tubulin<\/strong> in parasite cells, preventing microtubule polymerisation. This blocks parasite glucose uptake and depletes glycogen stores &mdash; the worm starves over 2&ndash;3 days. Mebendazole&rsquo;s oral bioavailability is very low (&lt; 10%), which is therapeutically useful: high concentrations stay in the gut lumen where intestinal worms live, with minimal systemic exposure.<\/p>\n<h2 class=\"wp-block-heading\">Lupimeb indications and dose<\/h2>\n<table style=\"width:100%;border-collapse:collapse;margin:14px 0;font-size:14px;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Indikasjon<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Dose<\/th>\n<th style=\"padding:8px;text-align:left;border:1px solid #ddd;\">Doseringsskjema<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Pinworm (Enterobius)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100 mg<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">Single dose, repeat at 2 weeks<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Roundworm (Ascaris)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Hookworm (Ancylostoma, Necator)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:8px;border:1px solid #ddd;\">Piskeorm (Trichuris)<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days; may extend to 5&ndash;7 days for heavy load<\/td>\n<\/tr>\n<tr>\n<td style=\"padding:8px;border:1px solid #ddd;\">Mixed nematode infection<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">100&nbsp;mg BID<\/td>\n<td style=\"padding:8px;border:1px solid #ddd;\">For 3 days<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Tablets can be chewed, swallowed whole, or crushed and mixed with food.<\/p>\n<div style=\"background:#eef7ee;border-left:4px solid #4caf50;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Pinworm protocol.<\/strong> Pinworm requires a second 100&nbsp;mg dose at 2 weeks because eggs already laid before the first dose hatch and complete a new cycle. Treat all household contacts on the same days. Wash bedding, towels, and underwear in hot water. Trim and scrub fingernails morning and night during the treatment window.<\/div>\n<h2 class=\"wp-block-heading\">Bivirkninger<\/h2>\n<ul>\n<li><strong>Vanlig:<\/strong> mild abdominal pain, transient diarrhoea, flatulence as worms pass<\/li>\n<li><strong>Mindre vanlige:<\/strong> headache, dizziness, mild rash<\/li>\n<li><strong>Sjeldne:<\/strong> reversible neutropenia (high-dose long courses), elevated transaminases, alopecia (very rare)<\/li>\n<li><strong>Sv\u00e6rt sjeldent:<\/strong> Stevens-Johnson syndrome, toxic epidermal necrolysis<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Legemiddelinteraksjoner<\/h2>\n<ul>\n<li><strong>Cimetidin<\/strong> &mdash; raises mebendazole plasma levels modestly; clinically relevant only in long courses for tissue parasites<\/li>\n<li><strong>Fenytoin, karbamazepin, rifampicin<\/strong> &mdash; reduce mebendazole levels (CYP induction)<\/li>\n<li><strong>Metronidazol<\/strong> &mdash; case reports of Stevens-Johnson syndrome with concurrent use; avoid if possible<\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Graviditet og amming.<\/strong> Albendazol og mebendazol anbefales IKKE i f\u00f8rste trimester (data om teratogenitet fra dyrefors\u00f8k). Bruk er akseptabelt i 2.\/3. trimester ved moderat til tung ormebyrde. Data om ivermectin under graviditet er begrenset, men tilfredsstillende i WHOs massebehandlingsprogrammer; unng\u00e5 i f\u00f8rste trimester der alternativer finnes. Praziquantel og pyrantel er kompatible med graviditet.<\/div>\n<div style=\"background:#f4f8fb;border-left:4px solid #2c7cb0;padding:14px 18px;margin:18px 0;border-radius:4px;font-size:14px;line-height:1.55;color:#444;\"><strong>Pediatrisk merknad.<\/strong> De fleste antihelmintika er trygge fra 2 \u00e5rs alder og oppover; ivermectin er godkjent fra 15 kg kroppsvekt; albendazol 400 mg engangsdose er WHOs standard fra 1 \u00e5rs alder i massebehandlingsprogrammer. Under 2 \u00e5rs alder, velg pediatriske suspensjoner og konsulter en kliniker for vektbasert dosering.<\/div>\n<h2 class=\"wp-block-heading\">Kontraindikasjoner<\/h2>\n<ul>\n<li>Hypersensitivity to mebendazole or other benzimidazoles<\/li>\n<li>Barn under 1 \u00e5r<\/li>\n<li>F\u00f8rste trimester av svangerskap<\/li>\n<li>Alvorlig leversvikt<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Oppbevaring<\/h2>\n<p>Store Lupimeb below 30&deg;C in the original blister, away from light and moisture.<\/p>\n<h3 class=\"wp-block-heading\">Hvorfor bestille fra MedsBase<\/h3>\n<p>Lupimeb is supplied from a <strong>WHO-GMP-sertifisert produsent<\/strong>, diskr\u00e9 pakket og sendt over hele verden. Hver bestilling er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\">Reshipment Assurance Policy<\/a> \u2014 du tar aldri kostnaden for en tapt pakke.<\/p>\n<h2 id=\"faqs\">Vanlige sp\u00f8rsm\u00e5l<\/h2>\n<h3 class=\"wp-block-heading\">Can I just take one tablet?<\/h3>\n<p>For pinworm, yes &mdash; one 100&nbsp;mg dose, then a second at 2 weeks. For roundworm, hookworm, whipworm, or mixed infection, the standard course is 100&nbsp;mg twice daily for 3 days.<\/p>\n<h3 class=\"wp-block-heading\">Do I need to fast before Lupimeb?<\/h3>\n<p>No. Mebendazole works locally in the gut lumen and absorption is intentionally low. Take with or without food.<\/p>\n<h3 class=\"wp-block-heading\">Can my child chew Lupimeb?<\/h3>\n<p>Yes &mdash; the tablet is designed to be chewed, swallowed whole, or crushed into food. Chewing is fine for children old enough to spit out anything they dislike (typically age 4+).<\/p>\n<h3 class=\"wp-block-heading\">How is mebendazole different from albendazole?<\/h3>\n<p>Both are benzimidazoles with the same mechanism. Albendazole has higher systemic absorption (better for tissue-dwelling parasites like echinococcus), while mebendazole stays mostly in the gut lumen (preferred for some paediatric protocols and patients with hepatic impairment). For routine intestinal nematodes, both work.<\/p>\n<h3 class=\"wp-block-heading\">Will Lupimeb treat tapeworm?<\/h3>\n<p>Mebendazole has activity against some intestinal cestodes (Hymenolepis nana) but is NOT first-line for tapeworm. Use niclosamide or praziquantel for confirmed Taenia infection.<\/p>\n<h3 class=\"wp-block-heading\">How long until the worms are gone?<\/h3>\n<p>Adult worms are paralysed within 24&ndash;48&nbsp;hours and pass in faeces over the following 3&ndash;5 days. Visible worms in stool are normal and a sign the drug is working. Itching and other symptoms resolve within 1&ndash;2 weeks.<\/p>\n<h3 class=\"wp-block-heading\">Is Lupimeb safe in pregnancy?<\/h3>\n<p>Avoid in the first trimester. After week 13, mebendazole is acceptable for moderate-to-heavy worm burden &mdash; discuss with a clinician.<\/p>\n<h3 class=\"wp-block-heading\">Can I drink alcohol with Lupimeb?<\/h3>\n<p>There is no specific alcohol interaction. Heavy alcohol use stresses the liver, and if the worm load is heavy enough to cause transient transaminase rise, abstaining for the treatment course is prudent.<\/p>\n<h3 class=\"wp-block-heading\">Does Lupimeb treat lice or scabies?<\/h3>\n<p>No. Mebendazole has no activity against ectoparasites &mdash; use ivermectin or permethrin for scabies and pediculicide shampoos or oral ivermectin for lice.<\/p>\n<h3 class=\"wp-block-heading\">Should I retest after treatment?<\/h3>\n<p>For routine pinworm or hookworm in an immunocompetent person with symptom resolution, no follow-up testing is needed. Persistent eosinophilia, weight loss, or recurring symptoms warrant repeat stool ova-and-parasite testing 2&ndash;4 weeks after treatment.<\/p>\n<p class=\"medsbase-link-boost-2026-05-07\" data-marker=\"mb-link-boost-wormentel\">Patients seeking extended parasite coverage beyond <a href=\"\/nb\/lupimeb\/\">Lupimeb<\/a> (mebendazole 100&nbsp;mg) may consider <a href=\"\/nb\/wormentel\/\">Wormentel (fenbendazol 222 \/ 500 mg)<\/a> as a fenbendazole alternative in the same benzimidazole class but with a broader organism spectrum covering Giardia, tapeworm, and Trichinella.<\/p>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Andre antiparasitt\u00e6re legemidler<\/h3>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/mebex\/\">Mebex (mebendazol 100 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/lupimeb\/\">Lupimeb (mebendazole 100 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/abd-400-albendazole\/\">ABD 400 (albendazol 400 mg)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/nemocid\/\">Nemocid (pyrantelpamoat)<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/iverheal\/\">Iverheal (ivermectin)<\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:22px 0;border-radius:4px;font-size:14px;color:#444;\"><strong>Medisinsk ansvarsfraskrivelse.<\/strong> Denne siden er kun til informasjonsform\u00e5l og erstatter ikke profesjonell medisinsk r\u00e5dgivning. Snakk med en kvalifisert lege f\u00f8r du starter med noen antihelmintisk behandling, spesielt hvis du er gravid eller ammer, har nedsatt immunforsvar, skal behandle et barn under 2 \u00e5r, eller hvis symptomene vedvarer etter en behandlingsperiode. Eosinofili, vekttap, vedvarende magesmerter eller reiserelaterte symptomer krever klinisk vurdering. Alvorlige parasittiske sykdommer (neurocysticerkose, strongyloides hyperinfeksjon, schistosomiasis med organskade) h\u00e5ndteres av spesialister.<\/div>","protected":false},"excerpt":{"rendered":"<p>Lupimeb (mebendazole 100 mg chewable, Lupin) \u2014 benzimidazole anthelmintic for pinworm, roundworm, hookworm, and whipworm. Single-dose for pinworm; 3-day course for roundworm and whipworm.<\/p>","protected":false},"featured_media":58689,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[3141,3342,3856],"product_tag":[4543,4544],"class_list":{"0":"post-58688","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-general-health","8":"product_cat-threadworm-treatment","9":"product_tag-lupimeb","10":"product_tag-mebendazole","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product\/58688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/comments?post=58688"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media\/58689"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media?parent=58688"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_brand?post=58688"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_cat?post=58688"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_tag?post=58688"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}