{"id":59417,"date":"2024-02-28T05:57:20","date_gmt":"2024-02-28T05:57:20","guid":{"rendered":"https:\/\/medsname.com\/nilol\/"},"modified":"2026-05-01T10:49:15","modified_gmt":"2026-05-01T10:49:15","slug":"nilol","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nb\/product\/nilol\/","title":{"rendered":"Nilol"},"content":{"rendered":"<p><!-- medsbase-tldr-answer --><\/p>\n<div style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 24px 0;border-radius:4px;\">\n<h2 id=\"faqs\">Vanlige sp\u00f8rsm\u00e5l<\/h2>\n<h3 class=\"wp-block-heading\" style=\"margin:0 0 8px 0;font-size:16px;font-weight:700;\">&#9889; Quick Answer &mdash; What is Nilol?<\/h3>\n<p style=\"margin:0;\"><strong>Nilol<\/strong> er en <strong>fixed-dose combination of atenolol (beta-blocker) + nifedipine (dihydropyridine calcium-channel blocker)<\/strong> from a WHO-GMP certified manufacturer &mdash; widely prescribed in India and the subcontinent for combined hypertension and angina, particularly in patients where a single-drug regimen has failed. The two drugs work via complementary mechanisms: atenolol reduces cardiac output and heart rate (beta-1 blockade); nifedipine causes direct arterial vasodilation via L-type calcium channel blockade. The beta-blocker blunts the reflex tachycardia that bare nifedipine would otherwise produce. Typical dose: <strong>\u00e9n tablett \u00e9n gang daglig<\/strong>. Contraindications inherit from both components: <strong>asthma \/ severe COPD \/ second-third degree heart block \/ acute heart failure \/ severe aortic stenosis \/ recent MI \/ cardiogenic shock<\/strong>.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Hva du f\u00e5r med MedsBase:<\/strong> WHO-GMP-sertifisert produsent \u00b7 Diskret emballasje \u00b7 Verdensomspennende levering \u00b7 1 400+ verifiserte <a href=\"https:\/\/medsbase.com\/nb\/reviews\/\">kundeanmeldelser<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis pakken din ikke ankommer innen 20 virkedager, sender vi ny.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>V\u00e5re generiske legemidler kommer fra WHO-GMP-sertifiserte produsenter og sendes over hele verden i diskret, n\u00f8ytral emballasje \u2014 ingen legemiddelnavn p\u00e5 utsiden av pakken. Kortbetalinger h\u00e5ndteres av en regulert betalingsbehandler (kontoutskrifter viser en regulert kortbetalingsprosessor \u2014 aldri \u201cMedsBase\u201d eller noe legemiddelnavn). Krypto og SEPA bankoverf\u00f8rsel godtas ogs\u00e5. Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy.<\/p>\n<h2 class=\"wp-block-heading\">What Is Nilol?<\/h2>\n<p>Nilol is an oral tablet from a WHO-GMP certified manufacturer containing:<\/p>\n<ul>\n<li><strong>Atenolol 50 mg<\/strong> &mdash; a cardioselective beta-1 blocker (the same molecule in <a href=\"https:\/\/medsbase.com\/nb\/atenheal\/\">Atenheal<\/a>)<\/li>\n<li><strong>Nifedipine 20 mg<\/strong> &mdash; a dihydropyridine calcium-channel blocker (extended-release; same molecule in <a href=\"https:\/\/medsbase.com\/nb\/depin\/\">Depin<\/a>, <a href=\"https:\/\/medsbase.com\/nb\/nicardia-retard\/\">Nicardia Retard<\/a>)<\/li>\n<\/ul>\n<p>The combination originated in 1980s European cardiology (brand Tenif, Tenoretic) and remains popular in India for patients with both hypertension and stable angina. The two drugs target different mechanisms: atenolol for heart-rate and contractility reduction; nifedipine for direct arterial vasodilation. The beta-blocker prevents the reflex tachycardia that nifedipine monotherapy would otherwise cause.<\/p>\n<h2 class=\"wp-block-heading\">How Nilol Works<\/h2>\n<ul>\n<li><strong>Atenolol<\/strong> &mdash; beta-1 blockade in the SA node reduces heart rate; blockade in ventricular myocardium reduces contractility. Lower cardiac output = lower blood pressure; lower myocardial oxygen demand = less angina.<\/li>\n<li><strong>Nifedipin<\/strong> &mdash; L-type calcium channel blockade in arterial smooth muscle causes direct arterial dilation. Reduces systemic vascular resistance and coronary vasospasm.<\/li>\n<li><strong>Komplement\u00e6r paring<\/strong> &mdash; bare nifedipine would cause reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control without the palpitation side effect.<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Bruk og dosering<\/h2>\n<ul>\n<li><strong>Combined hypertension + stable angina<\/strong> \u2014 prim\u00e6r indikasjon<\/li>\n<li><strong>Resistent hypertensjon<\/strong> &mdash; step-up therapy when single-agent has failed<\/li>\n<li><strong>Hypertension with coronary artery disease<\/strong><\/li>\n<\/ul>\n<p><strong>Dose:<\/strong> one tablet once daily, usually morning. Maximum 2 tablets\/day. Target BP &lt;140\/90 (or &lt;130\/80 with comorbidity).<\/p>\n<p><strong>Overv\u00e5kning:<\/strong> baseline + periodic ECG (atenolol bradycardia \/ nifedipine effect on PR interval), pulse, BP, peripheral oedema (nifedipine commonly causes ankle swelling).<\/p>\n<h2 class=\"wp-block-heading\">Bivirkninger<\/h2>\n<p><strong>Atenolol-related:<\/strong> fatigue, cold extremities, bradycardia, exercise intolerance, mild fatigue, erectile dysfunction, masked hypoglycaemia in diabetics.<\/p>\n<p><strong>Nifedipine-related:<\/strong><\/p>\n<ul>\n<li><strong>Ankelo\u00f8dem<\/strong> (peripheral swelling) &mdash; dose-related; occurs in up to 25% of long-term users<\/li>\n<li>Flushing, headache (vasodilation)<\/li>\n<li>Gingival hyperplasia (gum overgrowth)<\/li>\n<li>Forstoppelse<\/li>\n<li>Hot flashes, particularly at onset of therapy<\/li>\n<\/ul>\n<h2 class=\"wp-block-heading\">Kontraindikasjoner<\/h2>\n<ul>\n<li>Asthma \/ severe COPD (atenolol component)<\/li>\n<li>Andre-\/tredjegrads hjerteblokk, sinusbradykardi &lt;50, syk sinussyndrom<\/li>\n<li>Acute decompensated heart failure, cardiogenic shock<\/li>\n<li>Severe aortic stenosis (nifedipine can worsen)<\/li>\n<li>Recent myocardial infarction, unstable angina (short-acting nifedipine concern; the ER form is safer)<\/li>\n<li>Severe renal impairment (eGFR &lt;15 &mdash; atenolol dose reduction needed; prefer non-renally-cleared beta-blocker)<\/li>\n<li>Pregnancy (both components)<\/li>\n<li>Overf\u00f8lsomhet mot en av komponentene<\/li>\n<\/ul>\n<h2>Oppbevaring<\/h2>\n<p>Store below 25&deg;C; protect from light.<\/p>\n<h3 class=\"wp-block-heading\">Why combine atenolol with nifedipine?<\/h3>\n<p>Complementary mechanisms and side-effect-mitigation. Bare nifedipine causes reflex tachycardia (sympathetic response to vasodilation); atenolol blocks that reflex, giving smoother BP control. For patients with both hypertension AND stable angina, the two drugs target both diseases simultaneously.<\/p>\n<h3 class=\"wp-block-heading\">What about the ankle swelling from nifedipine?<\/h3>\n<p>Dose-related peripheral oedema occurs in up to 25% of long-term nifedipine users. It is NOT from fluid overload &mdash; it is from pre-capillary vasodilation increasing hydrostatic pressure in the lower legs. Treatment: dose reduction, leg elevation, compression stockings, or switch to a non-dihydropyridine CCB (verapamil, diltiazem) or a different vasodilator class (ACE inhibitor, ARB).<\/p>\n<h3 class=\"wp-block-heading\">Why not use this in pregnancy?<\/h3>\n<p>Atenolol is associated with intrauterine growth restriction in pregnancy (more so than other beta-blockers) and neonatal bradycardia\/hypoglycaemia. For antihypertensive use in pregnancy, <a href=\"https:\/\/medsbase.com\/nb\/labebet\/\">labetalol<\/a>, methyldopa, and nifedipine-monotherapy (not this FDC) are the preferred options.<\/p>\n<h3 class=\"wp-block-heading\">Where can I buy Nilol online?<\/h3>\n<p>You can buy Nilol (atenolol + nifedipine 50 mg + 20 mg, 30-180 tablets) from MedsBase with discreet packaging and worldwide shipping.<\/p>\n<h2 class=\"wp-block-heading\">Relaterte betablokkere og antihypertensiva<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/beloc\/\">Beloc \u2014 Propranolol 10\/20\/40 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/betapro-sr\/\">Betapro SR \u2014 Propranolol 80 mg SR<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/metolar\/\">Metolar \u2014 Metoprololtartrat 25\/50\/100 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/metomac\/\">Metomac \u2014 Metoprolol 25 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/p-nolol\/\">P-Nolol \u2014 Propranolol 20\/40 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/topme\/\">Topme \u2014 Metoprolol 50 mg<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/high-blood-pressure-medication\/\"><strong>Se alle h\u00f8yt blodtrykksmedikamenter<\/strong><\/a><\/li>\n<\/ul>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:16px 20px;margin:24px 0;border-radius:4px;\"><strong>\u2695 Medisinsk ansvarsfraskrivelse.<\/strong> Denne siden er kun til informasjonsform\u00e5l og erstatter ikke medisinsk r\u00e5dgivning fra en kvalifisert helsepersonell. H\u00f8yt blodtrykk, hjertesvikt og arytmier krever diagnose, overv\u00e5kning og dosindividualisering av en lege \u2013 bruk alltid betablokkere under medisinsk veiledning.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Relaterte alternativer<\/h3>\n<p>Andre produkter innen <strong>Kroniske tilstander<\/strong> som kunder ogs\u00e5 ser p\u00e5:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/gtn-spray\/\">GTN-spray<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/vilano\/\">Vilano<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/symbicort-turbohaler\/\">Symbicort Turbohaler<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/olmezest-am\/\">Olmezest AM<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/cosart\/\">Cosart<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Nilol is a fixed-dose combination of atenolol 50 mg + nifedipine 20 mg \u2014 beta-blocker plus dihydropyridine calcium-channel blocker for combined hypertension and stable angina. Complementary mechanisms; atenolol blocks reflex tachycardia from nifedipine vasodilation. Once daily, morning. Not for pregnancy.<\/p>","protected":false},"featured_media":59418,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3141,3223,3260,3356],"product_tag":[3365,3390,4693],"class_list":{"0":"post-59417","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-category-overview","7":"product_cat-chronic-conditions","8":"product_cat-heart-blood-pressure","9":"product_cat-high-blood-pressure-medication","10":"product_tag-atenolol","11":"product_tag-nifedipine","12":"product_tag-nilol","14":"first","15":"instock","16":"shipping-taxable","17":"purchasable","18":"product-type-variable","19":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product\/59417","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/comments?post=59417"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media\/59418"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media?parent=59417"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_brand?post=59417"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_cat?post=59417"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_tag?post=59417"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}