{"id":61476,"date":"2024-02-28T07:42:25","date_gmt":"2024-02-28T07:42:25","guid":{"rendered":"https:\/\/medsname.com\/seretra\/"},"modified":"2026-04-30T10:23:34","modified_gmt":"2026-04-30T10:23:34","slug":"seretra","status":"publish","type":"product","link":"https:\/\/medsbase.com\/nb\/product\/seretra\/","title":{"rendered":"Seretra"},"content":{"rendered":"<div class=\"medsbase-tldr-answer\" style=\"background:#fff8e1;border-left:4px solid #f5a623;padding:18px 22px;margin:0 0 28px 0;border-radius:4px;\">\n<h3 style=\"margin:0 0 10px 0;font-size:18px;color:#1a1a1a;\">\u26a1 Quick Answer \u2014 What is Seretra?<\/h3>\n<p><strong>Seretra<\/strong> inneholder <strong>seratrodast 80 mg<\/strong>, en <strong>selective thromboxane A2 (TXA2) receptor antagonist<\/strong> used as preventer therapy for asthma and allergic rhinitis. Seratrodast blocks the TXA2 receptor on bronchial smooth muscle, eosinophils, and platelets \u2014 preventing TXA2-mediated bronchoconstriction, eosinophil recruitment, and airway hyperresponsiveness. It was developed and is mainly used in Japan; less widely available outside Asia. Used as add-on preventer alongside ICS in patients with persistent asthma. Onset of preventer benefit takes <strong>1\u20132 uker<\/strong> of daily dosing.<\/p>\n<\/div>\n<div class=\"medsbase-trust-strip\" style=\"background:#f4f8fb;border:1px solid #d8e3eb;padding:12px 16px;margin:16px 0;border-radius:4px;font-size:14px;\">\n<strong>Hva du f\u00e5r med MedsBase:<\/strong> WHO-GMP-sertifisert produsent \u00b7 Diskret emballasje \u00b7 Verdensomspennende levering \u00b7 1 400+ verifiserte <a href=\"https:\/\/medsbase.com\/nb\/reviews\/\">kundeanmeldelser<\/a>\n<\/div>\n<p class=\"medsbase-reship-line\" style=\"font-size:14px;color:#444;margin:8px 0 18px;\">\ud83d\udce6 Hver ordre er dekket av v\u00e5r <a href=\"https:\/\/medsbase.com\/nb\/medsbase-re-shipment-assurance-policy\/\"><strong>Reshipment Assurance Policy<\/strong><\/a> \u2014 hvis pakken din ikke ankommer innen 20 virkedager, sender vi ny.<\/p>\n<h3>Hvorfor bestille fra MedsBase<\/h3>\n<p>V\u00e5re generiske legemidler kommer fra WHO-GMP-sertifiserte produsenter og sendes over hele verden i diskret, n\u00f8ytral emballasje \u2014 ingen legemiddelnavn p\u00e5 utsiden av pakken. Kortbetalinger h\u00e5ndteres av en regulert betalingsbehandler (kontoutskrifter viser en regulert kortbetalingsprosessor \u2014 aldri \u201cMedsBase\u201d eller noe legemiddelnavn). Krypto og SEPA bankoverf\u00f8rsel godtas ogs\u00e5. Hver ordre er dekket av v\u00e5r Reshipment Assurance Policy.<\/p>\n<div style=\"background:#f4f8fb;border:1px solid #e0e0e0;padding:12px 18px;margin:0 0 24px 0;border-radius:4px;font-size:14px;text-align:center;\">\n<strong>\ud83d\udd12 Kryptert kasse<\/strong> \u00b7 <strong>\ud83d\udcb3 Verifisert betalingsbehandler<\/strong> \u00b7 <strong>\ud83d\ude9a Verdensomspennende frakt<\/strong> \u00b7 <strong>\u2b50 4,9\/5 fra 1 400+ kunder<\/strong>\n<\/div>\n<h2>What Is Seretra?<\/h2>\n<p>Seretra contains seratrodast \u2014 a niche anti-asthma agent introduced in Japan in 1995. Seratrodast targets the thromboxane A2 (TXA2) receptor \u2014 a contrast to leukotriene receptor antagonists (montelukast) which target the cysteinyl leukotriene receptor. Both TXA2 and leukotrienes are inflammatory mediators released during the allergic cascade.<\/p>\n<h2>How Does Seratrodast Work?<\/h2>\n<ul>\n<li><strong>TXA2 receptor blockade<\/strong> on bronchial smooth muscle prevents TXA2-mediated bronchoconstriction<\/li>\n<li><strong>Reduces eosinophil recruitment<\/strong> to airways<\/li>\n<li><strong>Decreases airway hyperresponsiveness<\/strong> over 1\u20132 weeks of dosing<\/li>\n<li><strong>Mild platelet inhibition<\/strong> \u2014 TXA2 is a potent platelet aggregator; this effect is rarely clinically significant<\/li>\n<\/ul>\n<h2>Bruk og indikasjoner<\/h2>\n<ul>\n<li><strong>Persisterende astma<\/strong> \u2014 add-on preventer when ICS alone is inadequate<\/li>\n<li><strong>Allergisk rhinit<\/strong> \u2014 tilskudd<\/li>\n<li><strong>Hostevariant astma<\/strong><\/li>\n<li><strong>Aspirin-exacerbated respiratory disease<\/strong> (AERD) \u2014 niche use<\/li>\n<\/ul>\n<h2>Seretra Dosage<\/h2>\n<table style=\"border-collapse:collapse;width:100%;margin:12px 0;\">\n<thead>\n<tr style=\"background:#2c7cb0;color:#fff;\">\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Pasient<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Dose<\/th>\n<th style=\"padding:10px;border:1px solid #ddd;text-align:left;\">Frekvens<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding:10px;border:1px solid #ddd;\">Voksne<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\"><strong>80 mg<\/strong><\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Once daily after dinner<\/td>\n<\/tr>\n<tr style=\"background:#f9f9f9;\">\n<td style=\"padding:10px;border:1px solid #ddd;\">Leverfunksjonsnedsettelse<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">Reduser dose med 50 %<\/td>\n<td style=\"padding:10px;border:1px solid #ddd;\">En gang daglig<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Side Effects of Seretra<\/h2>\n<ul>\n<li>Nausea, dyspepsia<\/li>\n<li>Hodepine<\/li>\n<li>Mild dizziness<\/li>\n<li>Mild forh\u00f8yelse av leverenzymer<\/li>\n<li>Rarely: rash, fatigue<\/li>\n<\/ul>\n<p><strong>Alvorlig \u2014 stopp og s\u00f8k hjelp:<\/strong><\/p>\n<ul>\n<li>Hepatitis (jaundice, dark urine, RUQ pain)<\/li>\n<li>Alvorlig allergisk reaksjon<\/li>\n<li>Alvorlig vedvarende oppkast<\/li>\n<\/ul>\n<h2>Advarsler og forholdsregler<\/h2>\n<ul>\n<li><strong>Overv\u00e5king av leverfunksjon:<\/strong> baseline LFTs and periodic monitoring during long-term use.<\/li>\n<li><strong>Fortsett med ICS<\/strong> if previously prescribed; seratrodast is add-on, not replacement.<\/li>\n<li><strong>Ikke et akuttmedikament.<\/strong> Use SABA (Asthalin, Levolin) for acute attacks.<\/li>\n<li><strong>Graviditet og amming:<\/strong> limited data; avoid unless benefit clear.<\/li>\n<li><strong>Bleeding disorders:<\/strong> mild TXA2 inhibition could theoretically prolong bleeding; rarely clinically significant.<\/li>\n<\/ul>\n<h2>Kontraindikasjoner<\/h2>\n<ul>\n<li>Hypersensitivity to seratrodast<\/li>\n<li>Alvorlig leversvikt<\/li>\n<li>Active hepatitis<\/li>\n<\/ul>\n<h2>Legemiddelinteraksjoner<\/h2>\n<ul>\n<li>Aspirin and other antiplatelet agents \u2014 additive bleeding risk (rarely clinically significant)<\/li>\n<li>Warfarin \u2014 monitor INR<\/li>\n<li>Other hepatotoxic drugs \u2014 monitor LFTs<\/li>\n<\/ul>\n<h2>Oppbevaring<\/h2>\n<ul>\n<li>Oppbevar under <strong>25\u00b0C<\/strong> p\u00e5 et kj\u00f8lig, t\u00f8rt sted unna direkte sollys.<\/li>\n<li>Oppbevar i originalemballasje til bruk for \u00e5 beskytte mot fuktighet og lys.<\/li>\n<li>Ikke bruk etter utl\u00f8psdatoen som st\u00e5r p\u00e5 strimlen.<\/li>\n<li>Oppbevar utilgjengelig for barn.<\/li>\n<\/ul>\n<h2>Relaterte alternativer p\u00e5 MedsBase<\/h2>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/asthalin-inhaler\/\"><strong>Asthalin Inhaler \u2014 salbutamol lindringsmiddel<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/budecort-inhaler\/\"><strong>Budecort Inhaler \u2014 budesonide ICS forebyggende<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/foracort-inhaler\/\"><strong>Foracort Inhaler \u2014 budesonide + formoterol ICS-LABA<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/montair\/\"><strong>Montair \u2014 montelukast LTRA tablett<\/strong><\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/tiova-inhaler\/\"><strong>Tiova Inhaler \u2014 tiotropium LAMA for KOLS<\/strong><\/a><\/li>\n<\/ul>\n<h2 id=\"faqs\">Vanlige sp\u00f8rsm\u00e5l<\/h2>\n<h3>How is seratrodast different from montelukast?<\/h3>\n<p>Both block specific allergic mediators. Montelukast (Montair) blocks the cysteinyl leukotriene CysLT1 receptor. Seratrodast blocks the thromboxane A2 receptor. Different mediators, different targets, similar add-on niche. Montelukast has more global use and a stronger evidence base; seratrodast is mainly used in Japan and parts of Asia.<\/p>\n<h3>Can I take Seretra alongside montelukast?<\/h3>\n<p>Combination is not standard. Discuss with your prescriber \u2014 there is no established additional benefit over ICS-LABA + LTRA.<\/p>\n<h3>How long until Seretra works?<\/h3>\n<p>1\u20132 weeks for noticeable improvement; 4\u20138 weeks for full preventer effect on exacerbation rate.<\/p>\n<h3>Is Seretra a rescue inhaler?<\/h3>\n<p>No \u2014 onset is far too slow. Use a SABA (Asthalin, Levolin) for acute attacks.<\/p>\n<h3>Why monitor liver function?<\/h3>\n<p>Mild liver enzyme elevation is a known side effect. Baseline LFTs and periodic monitoring are recommended.<\/p>\n<h3>Will Seretra replace my inhaler?<\/h3>\n<p>No \u2014 seratrodast is an oral add-on. Continue ICS or ICS-LABA inhaler therapy.<\/p>\n<h3>Is Seretra evidence-based?<\/h3>\n<p>Yes, but mainly through Japanese trials. Evidence base is smaller than for montelukast or ICS-LABA combinations. Reasonable as add-on in selected patients.<\/p>\n<h3>Can children take Seretra?<\/h3>\n<p>Limited paediatric data; specialist supervision required.<\/p>\n<h3>Is Seretra safe in pregnancy?<\/h3>\n<p>Limited data; avoid unless benefit clear.<\/p>\n<div style=\"background:#fff3f3;border-left:4px solid #d9534f;padding:14px 18px;margin:24px 0;border-radius:4px;font-size:13px;\"><strong>Medisinsk ansvarsfraskrivelse:<\/strong> Denne siden er opplysningsmessig og erstatter ikke profesjonell medisinsk r\u00e5dgivning. Alltid konsulter en kvalifisert helsepersonell f\u00f8r du starter, stopper eller endrer enhver inhalator eller respirasjonsmedisin, spesielt hvis du har andre medisinske tilstander, tar andre reseptbelagte legemidler, er gravid eller ammer, eller er over 65 \u00e5r.<\/div>\n<p><!-- medsbase-related-alts-v1 --><\/p>\n<h3 class=\"wp-block-heading\">Relaterte alternativer<\/h3>\n<p>Andre produkter innen <strong>Kroniske tilstander<\/strong> som kunder ogs\u00e5 ser p\u00e5:<\/p>\n<ul>\n<li><a href=\"https:\/\/medsbase.com\/nb\/tenof-em\/\">Tenof EM<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/headset\/\">Headset<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/maxiflo-rotacaps\/\">Maxiflo Rotacaps<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/neomercazole\/\">Neomercazole<\/a><\/li>\n<li><a href=\"https:\/\/medsbase.com\/nb\/tridon\/\">Tridon<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>\u2705 Reduserer luftveisbetennelse<br \/>\n\u2705 Forbedrer lungefunksjon<br \/>\n\u2705 Lindrer astmasymptomer<br \/>\n\u2705 Prevents bronchoconstriction<br \/>\n\u2705 Enhances respiratory health<\/p>\n<p>Seretra contains Seratrodast.<\/p>","protected":false},"featured_media":61477,"comment_status":"open","ping_status":"open","template":"","meta":[],"product_brand":[],"product_cat":[3681,3141,3223],"product_tag":[5040,5041],"class_list":{"0":"post-61476","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-asthma-copd-treatment","7":"product_cat-category-overview","8":"product_cat-chronic-conditions","9":"product_tag-seratrodast","10":"product_tag-seretra","12":"first","13":"instock","14":"shipping-taxable","15":"purchasable","16":"product-type-variable","17":"has-default-attributes"},"acf":[],"_links":{"self":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product\/61476","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/comments?post=61476"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media\/61477"}],"wp:attachment":[{"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/media?parent=61476"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_brand?post=61476"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_cat?post=61476"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/medsbase.com\/nb\/wp-json\/wp\/v2\/product_tag?post=61476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}